Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:11-deoxycortisol
go back to main search page
Accession:CHEBI:28324 term browser browse the term
Definition:A deoxycortisol that is cortisol in which the hydroxy group at position 11 has been replaced by a hydrogen.
Synonyms:exact_synonym: 17,21-dihydroxypregn-4-ene-3,20-dione
 related_synonym: 11-desoxy-17-hydroxycorticosterone;   Cortodoxone;   Formula=C21H30O4;   InChI=1S/C21H30O4/c1-19-8-5-14(23)11-13(19)3-4-15-16(19)6-9-20(2)17(15)7-10-21(20,25)18(24)12-22/h11,15-17,22,25H,3-10,12H2,1-2H3/t15-,16+,17+,19+,20+,21+/m1/s1;   InChIKey=WHBHBVVOGNECLV-OBQKJFGGSA-N;   SMILES=[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@@]1(C)[C@@]2([H])CC[C@]1(O)C(=O)CO
 alt_id: CHEBI:19124;   CHEBI:714
 xref: Beilstein:2511358;   CAS:152-58-9;   HMDB:HMDB0000015;   KEGG:C05488;   KEGG:D03595;   LIPID_MAPS_instance:LMST02030086
 xref_mesh: MESH:D003350
 xref: PMID:18958601;   PMID:24863084;   Reaxys:2511358;   Wikipedia:Cortexolone


show annotations for term's descendants           Sort by:
11-deoxycortisol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO Cortodoxone binds to and results in increased activity of AR protein mutant form CTD PMID:11956172 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 increases metabolic processing
affects metabolic processing		 ISO CYP11B1 protein results in increased metabolism of Cortodoxone
CYP11B1 protein affects the metabolism of Cortodoxone		 CTD PMID:15522937 PMID:15780661 PMID:15985365 PMID:16030167 PMID:16054388 More... NCBI chr 7:106,838,590...106,845,004
Ensembl chr 7:106,838,590...106,845,004 		JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 increases metabolic processing
affects metabolic processing		 ISO CYP11B2 protein results in increased metabolism of Cortodoxone
CYP11B2 protein affects the metabolism of Cortodoxone		 CTD PMID:15743198 PMID:19900470 NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 affects binding ISO Cortodoxone binds to NR3C1 protein CTD PMID:15705660 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 increases activity ISO Cortodoxone results in increased activity of NR3C2 protein CTD PMID:15780662 NCBI chr19:30,715,634...31,059,885
Ensembl chr19:30,715,648...31,059,885 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19922
    role 19894
      application 19735
        anti-inflammatory agent 16628
          anti-inflammatory drug 14978
            cortisol 276
              deoxycortisol 5
                11-deoxycortisol 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19922
    subatomic particle 19892
      composite particle 19892
        hadron 19920
          baryon 19892
            nucleon 19920
              atomic nucleus 19892
                atom 19892
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19805
                        carbon atom 19802
                          organic molecular entity 19775
                            heteroorganic entity 19556
                              organochalcogen compound 19315
                                organooxygen compound 19205
                                  carbonyl compound 18949
                                    ketone 17196
                                      oxyketone 8912
                                        alpha-oxyketone 8917
                                          alpha-hydroxy ketone 8917
                                            primary alpha-hydroxy ketone 7798
                                              cortisol 276
                                                deoxycortisol 5
                                                  11-deoxycortisol 5
paths to the root