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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:daidzein
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Accession:CHEBI:28197 term browser browse the term
Definition:A member of the class of 7-hydroxyisoflavones that is 7-hydroxyisoflavone substituted by an additional hydroxy group at position 4'.
Synonyms:exact_synonym: 7-hydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one
 related_synonym: 4',7-dihydroxyisoflavone;   7-Hydroxy-3-(4-hydroxyphenyl)-4-benzopyrone;   7-hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one;   Formula=C15H10O4;   InChI=1S/C15H10O4/c16-10-3-1-9(2-4-10)13-8-19-14-7-11(17)5-6-12(14)15(13)18/h1-8,16-17H;   InChIKey=ZQSIJRDFPHDXIC-UHFFFAOYSA-N;   SMILES=Oc1ccc(cc1)-c1coc2cc(O)ccc2c1=O;   daidzeol;   isoaurostatin
 alt_id: CHEBI:23558;   CHEBI:4306
 xref: CAS:486-66-8;   HMDB:HMDB0003312;   KEGG:C10208;   KNApSAcK:C00009380;   LINCS:LSM-2935;   LIPID_MAPS_instance:LMPK12050038
 xref_mesh: MESH:C004742
 xref: MetaCyc:DAIDZEIN;   PMID:11193416;   PMID:16802696;   PMID:23267126;   PMID:23337939;   PMID:23342971;   PMID:23439294;   PMID:9544566;   Reaxys:231523;   Wikipedia:Daidzein
 cyclic_relationship: is_conjugate_acid_of CHEBI:77764


show annotations for term's descendants           Sort by:
daidzein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of ABCA1 mRNA CTD PMID:16963248 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO daidzein inhibits the reaction [Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]] CTD PMID:34217736 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO daidzein promotes the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate] CTD PMID:16156793 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions ISO daidzein inhibits the reaction [ABCC4 protein results in increased export of Cyclic GMP]; daidzein promotes the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate] CTD PMID:16156793 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283 		JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 multiple interactions ISO daidzein inhibits the reaction [ABCC5 protein results in decreased susceptibility to Thioguanine]; daidzein inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein] CTD PMID:16156793 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 affects transport ISO ABCG2 protein affects the transport of daidzein CTD PMID:18322075 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of ACSL3 mRNA CTD PMID:27424125 NCBI chr 9:80,115,164...80,164,636
Ensembl chr 9:80,115,112...80,164,627 		JBrowse link
G Add2 adducin 2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of ADD2 mRNA CTD PMID:16963248 NCBI chr 4:118,444,594...118,538,505
Ensembl chr 4:118,497,416...118,538,505 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
increases activity
affects binding		 ISO daidzein binds to and results in increased activity of AHR protein
daidzein results in increased activity of AHR protein
daidzein binds to AHR protein		 CTD PMID:14644660 PMID:17869316 PMID:20436506 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ALDH1A2 mRNA CTD PMID:27424125 NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107 		JBrowse link
G Alpg alkaline phosphatase, germ cell increases expression ISO daidzein metabolite results in increased expression of ALPG mRNA CTD PMID:15993745 NCBI chr 9:87,748,721...87,761,500
Ensembl chr 9:87,753,648...87,757,836 		JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO [daidzein binds to ESR1 protein] which results in increased activity of ALPL protein; fulvestrant inhibits the reaction [[daidzein binds to ESR1 protein] which results in increased activity of ALPL protein] CTD PMID:12650720 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446 		JBrowse link
G Anpep alanyl aminopeptidase, membrane multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ANPEP mRNA CTD PMID:27424125 NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789 		JBrowse link
G Ar androgen receptor multiple interactions
decreases expression		 ISO
EXP		 daidzein promotes the reaction [TGFB1I1 protein results in increased activity of AR protein]
daidzein results in decreased expression of AR mRNA
daidzein inhibits the reaction [Flutamide results in decreased expression of AR mRNA]; daidzein inhibits the reaction [Flutamide results in decreased expression of AR protein]		 CTD PMID:10822019 PMID:17252558 PMID:23135684 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha decreases expression ISO daidzein results in decreased expression of ARHGDIA mRNA CTD PMID:15757668 NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023 		JBrowse link
G Atoh8 atonal bHLH transcription factor 8 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of ATOH8 mRNA CTD PMID:27424125 NCBI chr 4:104,259,992...104,292,168
Ensembl chr 4:104,259,992...104,292,168 		JBrowse link
G Atp6v0a2 ATPase H+ transporting V0 subunit a2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of ATP6V0A2 mRNA CTD PMID:16963248 NCBI chr12:31,947,220...31,979,875
Ensembl chr12:31,822,733...32,007,069 		JBrowse link
G Baz1a bromodomain adjacent to zinc finger domain, 1A multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of BAZ1A mRNA CTD PMID:16963248 NCBI chr 6:72,389,701...72,512,516
Ensembl chr 6:72,389,703...72,512,459 		JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of BCKDK mRNA CTD PMID:27424125 NCBI chr 1:182,515,335...182,520,007
Ensembl chr 1:182,515,327...182,536,633 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO daidzein results in decreased expression of BCL2 protein CTD PMID:12791511 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO daidzein results in decreased expression of BCL2L1 protein CTD PMID:12791511 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO [daidzein co-treated with ESR1 protein] results in increased expression of BGLAP mRNA; [daidzein co-treated with ESR2 protein] results in increased expression of BGLAP mRNA CTD PMID:19347870 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Bpgm bisphosphoglycerate mutase multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of BPGM mRNA CTD PMID:27424125 NCBI chr 4:63,139,730...63,168,581
Ensembl chr 4:63,140,018...63,168,581 		JBrowse link
G Brca1 BRCA1, DNA repair associated increases expression ISO daidzein results in increased expression of BRCA1 mRNA CTD PMID:17266178 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304 		JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B affects expression ISO daidzein affects the expression of BUB1B mRNA CTD PMID:15721199 NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547 		JBrowse link
G C3 complement C3 increases expression EXP daidzein results in increased expression of C3 mRNA CTD PMID:10822019 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Cabp5 calcium binding protein 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CABP5 mRNA CTD PMID:27424125 NCBI chr 1:74,350,811...74,363,830
Ensembl chr 1:74,350,811...74,363,830 		JBrowse link
G Cacybp calcyclin binding protein multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of CACYBP mRNA CTD PMID:27424125 NCBI chr13:72,437,485...72,447,810
Ensembl chr13:72,437,490...72,450,177 		JBrowse link
G Casp3 caspase 3 increases activity
increases expression		 ISO
EXP		 daidzein results in increased activity of CASP3 protein
daidzein results in increased expression of CASP3 protein		 CTD PMID:12791511 PMID:29217487 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8ap2 caspase 8 associated protein 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CASP8AP2 mRNA CTD PMID:27424125 NCBI chr 5:47,014,501...47,052,276
Ensembl chr 5:47,014,667...47,052,275 		JBrowse link
G Cat catalase multiple interactions ISO
EXP		 [Genistein co-treated with daidzein] inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]
daidzein inhibits the reaction [Flutamide results in decreased activity of CAT protein]		 CTD PMID:22981962 PMID:23135684 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccna2 cyclin A2 decreases expression ISO daidzein results in decreased expression of CCNA2 CTD PMID:21161820 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ccnd1 cyclin D1 increases expression ISO daidzein results in increased expression of CCND1 mRNA CTD PMID:17266178 PMID:19800779 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Cd200r1 CD200 receptor 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CD200R1 mRNA CTD PMID:27424125 NCBI chr11:55,886,937...55,921,217
Ensembl chr11:55,887,717...55,921,285 		JBrowse link
G Cd40 CD40 molecule multiple interactions ISO daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of CD40 protein] CTD PMID:21945492 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534 		JBrowse link
G Cd80 Cd80 molecule multiple interactions ISO daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of CD80 protein] CTD PMID:21945492 NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030 		JBrowse link
G Cd86 CD86 molecule multiple interactions ISO daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of CD86 protein] CTD PMID:21945492 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions
decreases activity		 ISO daidzein promotes the reaction [CDKN1A protein binds to CDK2 protein]
daidzein results in decreased activity of CDK2 protein		 CTD PMID:11322924 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases activity ISO daidzein results in decreased activity of CDK4 protein CTD PMID:21161820 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression		 ISO daidzein promotes the reaction [CDKN1A protein binds to CDK2 protein]; ESR2 affects the reaction [daidzein results in increased expression of CDKN1A] CTD PMID:11322924 PMID:21161820 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cfap251 cilia and flagella associated protein 251 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of CFAP251 mRNA CTD PMID:27424125 NCBI chr12:33,261,622...33,337,028
Ensembl chr12:33,261,476...33,293,932 		JBrowse link
G Chat choline O-acetyltransferase increases activity ISO daidzein results in increased activity of CHAT protein CTD PMID:16428827 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093 		JBrowse link
G Ckb creatine kinase B increases activity
multiple interactions		 ISO daidzein results in increased activity of CKB protein
Glucose inhibits the reaction [daidzein results in increased activity of CKB protein]		 CTD PMID:16621514 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315 		JBrowse link
G Clu clusterin decreases expression EXP daidzein results in decreased expression of CLU mRNA CTD PMID:10822019 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Comt catechol-O-methyltransferase decreases activity
multiple interactions
decreases expression		 ISO daidzein results in decreased activity of COMT protein
daidzein inhibits the reaction [COMT protein results in increased methylation of 4-hydroxyestradiol]; fulvestrant inhibits the reaction [daidzein results in decreased expression of COMT mRNA]		 CTD PMID:18192686 PMID:18497090 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Cox7a2l cytochrome c oxidase subunit 7A2 like increases expression ISO daidzein results in increased expression of COX7A2L mRNA CTD PMID:17266178 NCBI chr 6:11,184,064...11,198,287
Ensembl chr 6:11,184,285...11,198,273 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression ISO daidzein results in increased expression of CPT1A mRNA; daidzein results in increased expression of CPT1A protein CTD PMID:16362726 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP daidzein results in increased phosphorylation of and results in increased activity of CREB1 protein CTD PMID:16972265 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Crp C-reactive protein multiple interactions ISO [Genistein co-treated with daidzein] results in decreased expression of CRP protein CTD PMID:16332659 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Csnk2a2 casein kinase 2 alpha 2 affects expression ISO daidzein affects the expression of CSNK2A2 mRNA CTD PMID:15721199 NCBI chr19:9,556,443...9,596,080
Ensembl chr19:9,556,260...9,596,080 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression
multiple interactions		 ISO daidzein results in increased expression of CXCL12 mRNA
ESR1 protein inhibits the reaction [daidzein results in increased expression of CXCL12 mRNA]		 CTD PMID:23384675 PMID:28396216 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cybrd1 cytochrome b reductase 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CYBRD1 mRNA CTD PMID:27424125 NCBI chr 3:55,934,874...55,962,132
Ensembl chr 3:55,934,874...55,962,108 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of CYP11A1 mRNA CTD PMID:28964809 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity
multiple interactions
decreases expression		 ISO daidzein results in decreased activity of CYP19A1 protein
[Genistein co-treated with biochanin A co-treated with daidzein] results in decreased activity of CYP19A1 protein; [Genistein co-treated with biochanin A co-treated with daidzein] results in decreased expression of CYP19A1 mRNA
daidzein results in decreased expression of CYP19A1 mRNA		 CTD PMID:16023337 PMID:16965912 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity
multiple interactions
decreases expression		 ISO
EXP		 daidzein results in decreased activity of CYP1A1 protein
daidzein inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; daidzein inhibits the reaction [Omeprazole results in increased expression of CYP1A1 protein]
daidzein results in decreased expression of CYP1A1 mRNA
daidzein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; fulvestrant inhibits the reaction [daidzein results in decreased expression of CYP1A1 mRNA]		 CTD PMID:9395520 PMID:18420780 PMID:18451504 PMID:18497090 PMID:28985473 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO daidzein results in decreased activity of CYP1A2 protein CTD PMID:18420780 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 affects chemical synthesis
decreases activity		 ISO CYP1B1 protein affects the chemical synthesis of daidzein
daidzein results in decreased activity of CYP1B1 protein		 CTD PMID:15479032 PMID:18420780 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 decreases activity ISO daidzein results in decreased activity of CYP2A4 protein CTD PMID:18420780 NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases activity ISO daidzein results in decreased activity of CYP2C29 protein CTD PMID:18420780 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO daidzein results in decreased activity of CYP2D6 protein
daidzein results in decreased activity of CYP2D22 protein		 CTD PMID:18420780 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity
multiple interactions		 ISO
EXP		 daidzein results in decreased activity of CYP2E1 protein
daidzein inhibits the reaction [[CYP2E1 protein results in increased metabolism of 4-nitrophenol] which results in increased chemical synthesis of 4-nitrocatechol]		 CTD PMID:18420780 PMID:31870919 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression
decreases activity		 EXP
ISO		 daidzein results in increased expression of CYP3A4 mRNA
daidzein results in decreased activity of CYP3A4 protein		 CTD PMID:18420780 PMID:31870919 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Dedd death effector domain-containing affects expression ISO daidzein affects the expression of DEDD mRNA CTD PMID:15721199 NCBI chr13:83,755,874...83,769,982
Ensembl chr13:83,756,108...83,769,332 		JBrowse link
G Dennd2d DENN domain containing 2D multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of DENND2D mRNA CTD PMID:27424125 NCBI chr 2:193,973,231...193,992,275
Ensembl chr 2:193,973,231...193,992,270 		JBrowse link
G Dio1 iodothyronine deiodinase 1 affects expression EXP daidzein affects the expression of DIO1 mRNA CTD PMID:24793811 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970 		JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT1 mRNA CTD PMID:28964809 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT3A mRNA CTD PMID:28964809 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Dock3 dedicator of cyto-kinesis 3 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of DOCK3 mRNA CTD PMID:16963248 NCBI chr 8:107,552,462...107,903,527
Ensembl chr 8:107,552,463...107,903,514 		JBrowse link
G Dpp9 dipeptidyl peptidase 9 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of DPP9 mRNA CTD PMID:27424125 NCBI chr 9:1,011,347...1,046,337
Ensembl chr 9:1,011,351...1,046,541 		JBrowse link
G Dusp4 dual specificity phosphatase 4 decreases expression ISO daidzein results in decreased expression of DUSP4 mRNA CTD PMID:16865672 NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138 		JBrowse link
G Ebag9 estrogen receptor binding site associated antigen 9 increases expression ISO daidzein results in increased expression of EBAG9 mRNA CTD PMID:17266178 NCBI chr 7:75,810,950...75,828,902
Ensembl chr 7:75,810,594...75,861,248 		JBrowse link
G Edrf1 erythroid differentiation regulatory factor 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of EDRF1 mRNA CTD PMID:27424125 NCBI chr 1:188,441,514...188,478,743
Ensembl chr 1:188,441,634...188,478,701 		JBrowse link
G Efhd1 EF-hand domain family, member D1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of EFHD1 mRNA CTD PMID:27424125 NCBI chr 9:87,938,259...87,984,917
Ensembl chr 9:87,938,284...87,984,917 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO [daidzein co-treated with ESR1 protein] results in decreased expression of EGFR mRNA; [daidzein co-treated with ESR1 protein] results in decreased expression of EGFR protein; [daidzein co-treated with ESR2 protein] results in decreased expression of EGFR mRNA; [daidzein co-treated with ESR2 protein] results in decreased expression of EGFR protein CTD PMID:19347870 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Elk1 ETS transcription factor ELK1 multiple interactions EXP daidzein results in increased phosphorylation of and results in increased activity of ELK1 protein CTD PMID:16972265 NCBI chr  X:1,138,826...1,155,713
Ensembl chr  X:1,139,756...1,155,713 		JBrowse link
G Eno3 enolase 3 decreases expression ISO daidzein results in decreased expression of ENO3 mRNA CTD PMID:15757668 NCBI chr10:55,370,531...55,375,921
Ensembl chr10:55,366,975...55,375,921 		JBrowse link
G Epha1 Eph receptor A1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of EPHA1 mRNA CTD PMID:16963248 NCBI chr 4:71,246,409...71,260,920
Ensembl chr 4:71,246,409...71,260,846 		JBrowse link
G Ercc5 ERCC excision repair 5, endonuclease affects expression ISO daidzein affects the expression of ERCC5 mRNA CTD PMID:15721199 NCBI chr 9:46,309,477...46,354,478
Ensembl chr 9:46,309,389...46,354,472 		JBrowse link
G Espn espin multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of ESPN mRNA CTD PMID:16963248 NCBI chr 5:162,626,560...162,660,439
Ensembl chr 5:162,626,560...162,660,256 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
increases expression
increases activity
affects response to substance
affects binding
decreases expression		 ISO
EXP		 [daidzein binds to ESR1 protein] which results in increased activity of ALPL protein; [daidzein co-treated with ESR1 protein] results in decreased expression of EGFR mRNA; [daidzein co-treated with ESR1 protein] results in decreased expression of EGFR protein; [daidzein co-treated with ESR1 protein] results in increased expression of BGLAP mRNA; [daidzein co-treated with ESR1 protein] results in increased expression of BSP mRNA; daidzein binds to and results in increased activity of ESR1 protein; daidzein inhibits the reaction [bisphenol A results in decreased expression of ESR1 mRNA]; daidzein inhibits the reaction [Estradiol binds to ESR1 protein]; daidzein metabolite binds to and results in increased activity of ESR1 protein; daidzein metabolite promotes the reaction [NCOA2 protein binds to ESR1 protein]; daidzein promotes the reaction [Estradiol results in increased activity of ESR1 protein]; ESR1 protein affects the reaction [daidzein results in decreased expression of IL6 mRNA]; ESR1 protein affects the reaction [daidzein results in decreased secretion of IL6 protein]; ESR1 protein inhibits the reaction [daidzein results in increased expression of CXCL12 mRNA]; ESR1 protein inhibits the reaction [daidzein results in increased expression of GREB1 mRNA]; ESR1 protein inhibits the reaction [daidzein results in increased expression of PGR mRNA]; ESR1 protein inhibits the reaction [daidzein results in increased expression of PRSS23 mRNA]; ESR1 protein inhibits the reaction [daidzein results in increased expression of TFF1 mRNA]; Estradiol affects the reaction [daidzein metabolite affects the activity of ESR1 protein]; Fulvestrant inhibits the reaction [[daidzein binds to ESR1 protein] which results in increased activity of ALPL protein]
daidzein results in increased expression of ESR1 mRNA; daidzein results in increased expression of ESR1 protein
daidzein results in increased activity of ESR1 protein
ESR1 protein affects the susceptibility to daidzein
daidzein results in decreased expression of ESR1 mRNA; daidzein results in decreased expression of ESR1 protein		 CTD PMID:9751507 PMID:12598185 PMID:12650720 PMID:14579009 PMID:15084758 More... NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
increases expression
affects binding
affects response to substance
increases activity		 ISO
EXP		 [daidzein co-treated with ESR2 protein] results in decreased expression of EGFR mRNA; [daidzein co-treated with ESR2 protein] results in decreased expression of EGFR protein; [daidzein co-treated with ESR2 protein] results in increased expression of BGLAP mRNA; [daidzein co-treated with ESR2 protein] results in increased expression of BSP mRNA; [daidzein co-treated with ESR2 protein] results in increased expression of PTGS2 mRNA; daidzein binds to and results in increased activity of ESR2 protein; daidzein inhibits the reaction [Estradiol binds to ESR2 protein]; daidzein inhibits the reaction [KAT5 protein results in increased activity of ESR2 protein]; daidzein metabolite binds to and results in increased activity of ESR2 protein; daidzein promotes the reaction [Estradiol results in increased activity of ESR2 protein]; ESR2 affects the reaction [daidzein results in increased expression of CDKN1A]; ESR2 gene polymorphism affects the reaction [[Genistein co-treated with daidzein] affects the expression of VCAM1 protein]; ESR2 gene polymorphism affects the susceptibility to [Genistein co-treated with daidzein]; Estradiol affects the reaction [daidzein metabolite affects the activity of ESR2 protein]
daidzein results in increased expression of ESR2 mRNA; daidzein results in increased expression of ESR2 protein
[Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of ESR2 mRNA
daidzein binds to ESR2 protein
ESR2 affects the susceptibility to daidzein
daidzein results in increased activity of ESR2 protein
daidzein results in increased activity of ESR2 protein; daidzein results in increased activity of ESR2 protein alternative form		 CTD PMID:9751507 PMID:12224631 PMID:15084758 PMID:15993745 PMID:16033089 More... NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Esrra estrogen related receptor, alpha multiple interactions ISO daidzein binds to and results in increased activity of ESRRA protein; daidzein binds to and results in increased activity of ESRRA protein mutant form; daidzein promotes the reaction [ESRRA protein binds to PNRC1 protein] CTD PMID:14638870 NCBI chr 1:204,104,100...204,114,182
Ensembl chr 1:204,104,101...204,114,268 		JBrowse link
G Esrrb estrogen-related receptor beta multiple interactions ISO daidzein binds to and results in increased activity of ESRRB protein; daidzein promotes the reaction [ESRRB protein binds to PNRC1 protein] CTD PMID:14638870 NCBI chr 6:106,007,701...106,163,136
Ensembl chr 6:106,008,095...106,160,791 		JBrowse link
G Esrrg estrogen-related receptor gamma multiple interactions ISO daidzein inhibits the reaction [bisphenol A results in increased expression of ESRRG mRNA]; daidzein inhibits the reaction [bisphenol A results in increased expression of ESRRG protein]; daidzein promotes the reaction [ESRRG protein binds to PNRC1 protein] CTD PMID:14638870 PMID:32963737 NCBI chr13:99,167,656...99,788,016
Ensembl chr13:99,564,669...99,783,397 		JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions
increases expression		 ISO 2-chloro-5-nitrobenzanilide inhibits the reaction [daidzein results in increased expression of FABP4 mRNA] CTD PMID:30920877 NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578 		JBrowse link
G Fam171a2 family with sequence similarity 171, member A2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of FAM171A2 mRNA CTD PMID:27424125 NCBI chr10:87,393,888...87,404,051
Ensembl chr10:87,394,007...87,404,053 		JBrowse link
G Fam180a family with sequence similarity 180, member A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FAM180A mRNA CTD PMID:27424125 NCBI chr 4:63,992,867...64,008,047
Ensembl chr 4:63,992,867...64,008,047 		JBrowse link
G Fam210b family with sequence similarity 210, member B multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FAM210B mRNA CTD PMID:27424125 NCBI chr 3:161,118,228...161,128,400
Ensembl chr 3:161,118,239...161,128,397 		JBrowse link
G Fam241b family with sequence similarity 241 member B multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of FAM241B mRNA CTD PMID:27424125 NCBI chr20:30,052,315...30,055,247
Ensembl chr20:30,052,324...30,055,084
Ensembl chr 6:30,052,324...30,055,084 		JBrowse link
G Fermt2 FERM domain containing kindlin 2 affects expression ISO daidzein affects the expression of FERMT2 mRNA CTD PMID:15721199 NCBI chr15:18,682,927...18,751,959
Ensembl chr15:18,682,927...18,751,811 		JBrowse link
G Fgd6 FYVE, RhoGEF and PH domain containing 6 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of FGD6 mRNA CTD PMID:27424125 NCBI chr 7:28,597,609...28,712,908
Ensembl chr 7:28,597,609...28,712,456 		JBrowse link
G Fhl2 four and a half LIM domains 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FHL2 mRNA CTD PMID:27424125 NCBI chr 9:45,388,979...45,462,421
Ensembl chr 9:45,388,981...45,431,192 		JBrowse link
G Fmn2 formin 2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of FMN2 mRNA CTD PMID:16963248 NCBI chr13:86,454,256...86,771,437
Ensembl chr13:86,453,926...86,771,411 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression		 ISO daidzein inhibits the reaction [Estradiol results in increased expression of FOS mRNA]
daidzein results in increased expression of FOS mRNA		 CTD PMID:11473722 PMID:17142977 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Galnt15 polypeptide N-acetylgalactosaminyltransferase 15 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of GALNT15 mRNA CTD PMID:27424125 NCBI chr16:7,227,232...7,267,002
Ensembl chr16:7,227,271...7,267,014 		JBrowse link
G Gnb1 G protein subunit beta 1 multiple interactions EXP daidzein promotes the reaction [GNB1 protein results in increased activity of PLCB2 protein results in increased activity of MAPK1 protein]; daidzein promotes the reaction [GNB1 protein results in increased activity of PLCB2 protein results in increased activity of MAPK3 protein]; daidzein promotes the reaction [GNB1 protein results in increased activity of PLCB2 protein] CTD PMID:16972265 NCBI chr 5:166,075,508...166,142,223
Ensembl chr 5:166,075,629...166,142,124 		JBrowse link
G Gng5 G protein subunit gamma 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of GNG5 mRNA CTD PMID:27424125 NCBI chr 2:235,394,680...235,403,177
Ensembl chr 1:77,292,043...77,292,513
Ensembl chr11:77,292,043...77,292,513 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 multiple interactions ISO daidzein inhibits the reaction [bisphenol A results in decreased expression of GPER1 mRNA] CTD PMID:32963737 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889 		JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 increases expression
multiple interactions		 ISO daidzein results in increased expression of GREB1 mRNA
ESR1 protein inhibits the reaction [daidzein results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [daidzein results in increased expression of GREB1 mRNA]		 CTD PMID:23384675 PMID:33405908 NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP daidzein inhibits the reaction [Flutamide results in decreased activity of GSR protein] CTD PMID:23135684 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Hipk4 homeodomain interacting protein kinase 4 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of HIPK4 mRNA CTD PMID:27424125 NCBI chr 1:82,810,708...82,821,080
Ensembl chr 1:82,810,708...82,821,077 		JBrowse link
G Hmcn1 hemicentin 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of HMCN1 mRNA CTD PMID:27424125 NCBI chr13:62,615,461...63,084,524
Ensembl chr13:62,615,461...63,084,524 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of HSD3B1 mRNA CTD PMID:28964809 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 multiple interactions ISO daidzein inhibits the reaction [Colforsin results in increased expression of HSD3B2 mRNA] CTD PMID:23370353 NCBI chr 2:186,095,897...186,105,354
Ensembl chr 2:186,095,897...186,101,852 		JBrowse link
G Ibsp integrin-binding sialoprotein multiple interactions ISO [daidzein co-treated with ESR1 protein] results in increased expression of BSP mRNA; [daidzein co-treated with ESR2 protein] results in increased expression of BSP mRNA CTD PMID:19347870 NCBI chr14:5,439,825...5,452,570
Ensembl chr14:5,439,829...5,452,693 		JBrowse link
G Ifrd2 interferon-related developmental regulator 2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of IFRD2 mRNA CTD PMID:16963248 NCBI chr 8:108,260,969...108,266,191
Ensembl chr 8:108,260,969...108,266,194 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor decreases expression ISO daidzein results in decreased expression of IGF1R mRNA CTD PMID:16865672 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 increases expression ISO daidzein results in increased expression of IGFBP4 mRNA CTD PMID:15757668 NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225 		JBrowse link
G Il12a interleukin 12A multiple interactions ISO daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of IL12A mRNA] CTD PMID:21945492 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734 		JBrowse link
G Il12b interleukin 12B multiple interactions ISO daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]; daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein] CTD PMID:21945492 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il17a interleukin 17A multiple interactions ISO daidzein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA] CTD PMID:25583575 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO daidzein inhibits the reaction [Estradiol results in increased expression of IL1A mRNA] CTD PMID:11473722 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO daidzein inhibits the reaction [IL1B protein results in increased secretion of IL6 protein]
[Genistein co-treated with daidzein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]		 CTD PMID:17266178 PMID:22981962 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il4 interleukin 4 increases expression ISO daidzein results in increased expression of IL4 mRNA; daidzein results in increased expression of IL4 protein CTD PMID:16108819 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression
decreases secretion		 ISO daidzein inhibits the reaction [IL1B protein results in increased secretion of IL6 protein]; ESR1 protein affects the reaction [daidzein results in decreased expression of IL6 mRNA]; ESR1 protein affects the reaction [daidzein results in decreased secretion of IL6 protein]
[Genistein co-treated with daidzein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; daidzein inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]		 CTD PMID:17266178 PMID:21945492 PMID:21972936 PMID:22981962 PMID:27576059 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Il6r interleukin 6 receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of IL6R mRNA CTD PMID:27424125 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536 		JBrowse link
G Irf2bp1 interferon regulatory factor 2 binding protein 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of IRF2BP1 mRNA CTD PMID:16963248 NCBI chr 1:78,652,736...78,655,437
Ensembl chr 1:78,652,412...78,655,530 		JBrowse link
G Isg20l2 interferon stimulated exonuclease gene 20-like 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ISG20L2 mRNA CTD PMID:27424125 NCBI chr 2:173,396,780...173,407,102
Ensembl chr 2:173,396,780...173,406,614 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO daidzein results in increased expression of JUN mRNA CTD PMID:17266178 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kat5 lysine acetyltransferase 5 multiple interactions ISO daidzein inhibits the reaction [KAT5 protein results in increased activity of ESR2 protein] CTD PMID:23857583 NCBI chr 1:202,895,751...202,903,178
Ensembl chr 1:202,895,751...202,903,458 		JBrowse link
G Kcng2 potassium voltage-gated channel modifier subfamily G member 2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of KCNG2 mRNA CTD PMID:16963248 NCBI chr18:73,742,224...73,810,420
Ensembl chr18:73,743,074...73,808,723 		JBrowse link
G Kdm5a lysine demethylase 5A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of KDM5A mRNA CTD PMID:27424125 NCBI chr 4:153,565,909...153,643,912
Ensembl chr 4:153,565,846...153,642,422 		JBrowse link
G Kitlg KIT ligand multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of KITLG mRNA CTD PMID:27424125 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214 		JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 decreases expression ISO daidzein results in decreased expression of KLK3 mRNA CTD PMID:16865672 NCBI chr 1:94,402,993...94,407,052
Ensembl chr 1:94,402,993...94,407,052 		JBrowse link
G Knstrn kinetochore-localized astrin/SPAG5 binding protein multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of KNSTRN mRNA CTD PMID:27424125 NCBI chr 3:105,800,762...105,820,555
Ensembl chr 3:105,800,954...105,820,715 		JBrowse link
G Lamp3 lysosomal-associated membrane protein 3 decreases expression ISO daidzein results in decreased expression of LAMP3 mRNA CTD PMID:20678512 NCBI chr11:81,153,491...81,224,643
Ensembl chr11:81,193,649...81,221,784 		JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LDLRAP1 mRNA CTD PMID:27424125 NCBI chr 5:146,955,607...146,978,601
Ensembl chr 5:146,955,607...146,978,601 		JBrowse link
G Lmod1 leiomodin 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LMOD1 mRNA CTD PMID:27424125 NCBI chr13:46,754,048...46,796,186
Ensembl chr13:46,754,033...46,794,900 		JBrowse link
G Lrg1 leucine-rich alpha-2-glycoprotein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of LRG1 mRNA CTD PMID:27424125 NCBI chr 9:947,516...949,773
Ensembl chr 9:947,516...949,813 		JBrowse link
G Lsr lipolysis stimulated lipoprotein receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LSR mRNA CTD PMID:27424125 NCBI chr 1:86,185,769...86,201,952
Ensembl chr 1:86,186,431...86,201,952 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation		 ISO
EXP		 AG 1879 inhibits the reaction [daidzein results in increased phosphorylation of MAPK1 protein]
daidzein promotes the reaction [GNB1 protein results in increased activity of PLCB2 protein results in increased activity of MAPK1 protein]; daidzein results in increased phosphorylation of and results in increased activity of MAPK1 protein		 CTD PMID:16840783 PMID:16972265 PMID:24859791 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation		 ISO
EXP		 AG 1879 inhibits the reaction [daidzein results in increased phosphorylation of MAPK3 protein]
daidzein promotes the reaction [GNB1 protein results in increased activity of PLCB2 protein results in increased activity of MAPK3 protein]; daidzein results in increased phosphorylation of and results in increased activity of MAPK3 protein		 CTD PMID:16840783 PMID:16972265 PMID:24859791 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Me1 malic enzyme 1 increases expression ISO daidzein results in increased expression of ME1 mRNA CTD PMID:16865672 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions EXP daidzein inhibits the reaction [Flutamide results in increased expression of MMP9 mRNA] CTD PMID:23135684 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mrpl33 mitochondrial ribosomal protein L33 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of MRPL33 mRNA CTD PMID:27424125 NCBI chr 6:24,825,800...24,833,994
Ensembl chr 6:24,825,827...24,833,834 		JBrowse link
G Mt2A metallothionein 2A increases expression ISO daidzein results in increased expression of MT2A mRNA CTD PMID:10656621 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Mtmr11 myotubularin related protein 11 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of MTMR11 mRNA CTD PMID:27424125 NCBI chr 2:183,721,983...183,732,148
Ensembl chr 2:183,723,530...183,732,148 		JBrowse link
G Mybl1 MYB proto-oncogene like 1 increases expression
multiple interactions		 ISO daidzein results in increased expression of MYBL1 mRNA
Fulvestrant inhibits the reaction [daidzein results in increased expression of MYBL1 mRNA]		 CTD PMID:33405908 NCBI chr 5:9,582,905...9,618,179
Ensembl chr 5:9,582,934...9,618,183 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression ISO daidzein results in increased expression of MYC mRNA CTD PMID:17266178 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Myof myoferlin multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of MYOF mRNA CTD PMID:27424125 NCBI chr 1:235,673,666...235,822,413
Ensembl chr 1:235,673,666...235,822,334 		JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions
increases expression		 ISO [daidzein binds to THRB protein] promotes the reaction [NCOA1 protein binds to THRB protein]; daidzein promotes the reaction [NCOA1 protein binds to THRB protein]
daidzein results in increased expression of NCOA1 mRNA; daidzein results in increased expression of NCOA1 protein		 CTD PMID:27576059 PMID:29688519 NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664 		JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO daidzein metabolite promotes the reaction [NCOA2 protein binds to ESR1 protein] CTD PMID:15084758 NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO daidzein inhibits the reaction [Lipopolysaccharides results in increased localization of NFKB1 protein] CTD PMID:21972936 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO daidzein inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein] CTD PMID:21972936 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nkx3-1 NK3 homeobox 1 decreases expression ISO daidzein results in decreased expression of NKX3-1 mRNA CTD PMID:16865672 NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases activity		 ISO daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
daidzein results in decreased activity of NOS2 protein		 CTD PMID:11308324 PMID:18274639 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nos3 nitric oxide synthase 3 increases activity ISO daidzein results in increased activity of NOS3 protein CTD PMID:16840783 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression ISO daidzein results in decreased expression of NQO1 mRNA CTD PMID:18497090 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO daidzein binds to and results in increased activity of NR1I2 protein
daidzein binds to and results in decreased activity of NR1I2 protein		 CTD PMID:16054614 PMID:33049310 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of NR4A1 mRNA CTD PMID:27424125 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297 		JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 mRNA; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 protein; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased methylation of NR5A1 promoter; decitabine inhibits the reaction [[Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 mRNA] CTD PMID:28964809 NCBI chr 3:22,464,786...22,486,328
Ensembl chr 3:22,465,502...22,486,328 		JBrowse link
G Nrip1 nuclear receptor interacting protein 1 increases expression ISO daidzein results in increased expression of NRIP1 mRNA CTD PMID:15757668 NCBI chr11:14,895,843...14,979,490
Ensembl chr11:14,895,553...14,981,761 		JBrowse link
G Olfml3 olfactomedin-like 3 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of OLFML3 mRNA CTD PMID:16963248 NCBI chr 2:191,244,221...191,247,050
Ensembl chr 2:191,244,221...191,247,050 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO daidzein results in increased cleavage of PARP1 protein CTD PMID:12791511 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression ISO
EXP		 daidzein results in decreased expression of PCNA
daidzein results in decreased expression of PCNA protein		 CTD PMID:21161820 PMID:29217487 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pdlim2 PDZ and LIM domain 2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of PDLIM2 mRNA CTD PMID:16963248 NCBI chr15:45,235,421...45,250,187
Ensembl chr15:45,237,477...45,249,242 		JBrowse link
G Pdzk1 PDZ domain containing 1 increases expression ISO daidzein results in increased expression of PDZK1 mRNA CTD PMID:15757668 NCBI chr 2:184,376,161...184,407,514
Ensembl chr 2:184,376,161...184,407,514 		JBrowse link
G Pgr progesterone receptor increases expression
multiple interactions		 ISO daidzein results in increased expression of PGR mRNA; daidzein results in increased expression of PGR protein
ESR1 protein inhibits the reaction [daidzein results in increased expression of PGR mRNA]		 CTD PMID:17142977 PMID:23384675 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
G Plaur plasminogen activator, urokinase receptor multiple interactions EXP daidzein inhibits the reaction [Flutamide results in increased expression of PLAUR mRNA] CTD PMID:23135684 NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595 		JBrowse link
G Plcb2 phospholipase C, beta 2 multiple interactions EXP daidzein promotes the reaction [GNB1 protein results in increased activity of PLCB2 protein results in increased activity of MAPK1 protein]; daidzein promotes the reaction [GNB1 protein results in increased activity of PLCB2 protein results in increased activity of MAPK3 protein]; daidzein promotes the reaction [GNB1 protein results in increased activity of PLCB2 protein] CTD PMID:16972265 NCBI chr 3:105,683,676...105,704,384
Ensembl chr 3:105,684,815...105,704,302 		JBrowse link
G Pnn pinin, desmosome associated protein multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of PNN mRNA CTD PMID:16963248 NCBI chr 6:76,758,138...76,766,451
Ensembl chr 6:76,758,117...76,766,889 		JBrowse link
G Pnrc1 proline-rich nuclear receptor coactivator 1 multiple interactions ISO daidzein promotes the reaction [ESRRA protein binds to PNRC1 protein]; daidzein promotes the reaction [ESRRB protein binds to PNRC1 protein]; daidzein promotes the reaction [ESRRG protein binds to PNRC1 protein] CTD PMID:14638870 NCBI chr 5:47,647,070...47,657,832
Ensembl chr 5:47,647,071...47,650,161 		JBrowse link
G Pou4f2 POU class 4 homeobox 2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of POU4F2 mRNA CTD PMID:16963248 NCBI chr19:29,486,686...29,490,327
Ensembl chr19:29,486,686...29,490,327 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of PRKACA mRNA CTD PMID:27424125 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430 		JBrowse link
G Prkca protein kinase C, alpha increases activity EXP daidzein results in increased activity of PRKCA protein CTD PMID:16972265 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012 		JBrowse link
G Prkcb protein kinase C, beta increases activity EXP daidzein results in increased activity of PRKCB protein CTD PMID:16972265 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536 		JBrowse link
G Prkcd protein kinase C, delta decreases expression ISO daidzein results in decreased expression of PRKCD mRNA CTD PMID:15757668 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Prkce protein kinase C, epsilon multiple interactions EXP daidzein affects the localization of and results in increased activity of PRKCE protein CTD PMID:16972265 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719 		JBrowse link
G Prkcg protein kinase C, gamma increases activity EXP daidzein results in increased activity of PRKCG protein CTD PMID:16972265 NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384 		JBrowse link
G Prl prolactin increases secretion EXP daidzein results in increased secretion of PRL protein CTD PMID:19400946 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Prpf40a pre-mRNA processing factor 40 homolog A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of PRPF40A mRNA CTD PMID:27424125 NCBI chr 3:37,625,585...37,689,859
Ensembl chr 3:37,627,690...37,690,886 		JBrowse link
G Prss23 serine protease 23 increases expression
multiple interactions		 ISO daidzein results in increased expression of PRSS23 mRNA
ESR1 protein inhibits the reaction [daidzein results in increased expression of PRSS23 mRNA]		 CTD PMID:23384675 NCBI chr 1:143,402,725...143,422,182
Ensembl chr 1:143,401,396...143,422,091 		JBrowse link
G Pspc1 paraspeckle component 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of PSPC1 mRNA CTD PMID:27424125 NCBI chr15:30,828,617...30,911,315
Ensembl chr15:30,828,626...30,911,202 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [daidzein co-treated with ESR2 protein] results in increased expression of PTGS2 mRNA; daidzein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; daidzein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]
daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]		 CTD PMID:16870006 PMID:19347870 PMID:21341175 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Pth1r parathyroid hormone 1 receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of PTH1R mRNA CTD PMID:27424125 NCBI chr 8:110,693,910...110,725,458
Ensembl chr 8:110,697,485...110,719,729 		JBrowse link
G Ptk2 protein tyrosine kinase 2 increases phosphorylation ISO daidzein results in increased phosphorylation of PTK2 protein CTD PMID:12421874 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783 		JBrowse link
G Rac1 Rac family small GTPase 1 increases activity ISO daidzein results in increased activity of RAC1 protein CTD PMID:24859791 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
G Rassf5 Ras association domain family member 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of RASSF5 mRNA CTD PMID:27424125 NCBI chr13:42,637,513...42,703,024
Ensembl chr13:42,637,549...42,703,024 		JBrowse link
G Rbbp8 RB binding protein 8, endonuclease increases expression ISO daidzein results in increased expression of RBBP8 mRNA CTD PMID:15757668 NCBI chr18:2,922,985...2,988,851
Ensembl chr18:2,921,286...2,988,846 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO daidzein inhibits the reaction [Lipopolysaccharides affects the localization of and results in increased activity of RELA protein] CTD PMID:18274639 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Rgs22 regulator of G-protein signaling 22 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of RGS22 mRNA CTD PMID:27424125 NCBI chr 7:67,188,531...67,308,805
Ensembl chr 7:67,188,519...67,308,875 		JBrowse link
G Rps6ka3 ribosomal protein S6 kinase A3 increases expression ISO daidzein results in increased expression of RPS6KA3 mRNA CTD PMID:15757668 NCBI chr  X:35,517,306...35,623,296
Ensembl chr  X:35,517,306...35,623,207 		JBrowse link
G RT1-Bb RT1 class II, locus Bb multiple interactions ISO daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of H2-AB1 protein] CTD PMID:21945492 NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597 		JBrowse link
G S1pr3 sphingosine-1-phosphate receptor 3 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of S1PR3 mRNA CTD PMID:27424125 NCBI chr17:13,781,050...13,794,408
Ensembl chr17:13,781,050...13,794,505 		JBrowse link
G Selplg selectin P ligand multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SELPLG mRNA CTD PMID:27424125 NCBI chr12:42,796,690...42,809,908
Ensembl chr12:42,796,580...42,812,585 		JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 multiple interactions
increases expression		 ISO Fulvestrant inhibits the reaction [daidzein results in increased expression of SGK1 mRNA] CTD PMID:33405908 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283 		JBrowse link
G Sgpp1 sphingosine-1-phosphate phosphatase 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of SGPP1 mRNA CTD PMID:16963248 NCBI chr 6:94,425,339...94,446,534
Ensembl chr 6:94,425,339...94,446,534 		JBrowse link
G Siglec10 sialic acid binding Ig-like lectin 10 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of SIGLEC10 mRNA CTD PMID:27424125 NCBI chr 1:93,817,301...93,826,376
Ensembl chr 1:93,817,335...93,825,931 		JBrowse link
G Slc10a1 solute carrier family 10 member 1 multiple interactions
increases transport		 ISO daidzein metabolite inhibits the reaction [SLC10A1 protein results in increased transport of estrone sulfate]; daidzein metabolite promotes the reaction [SLC10A1 protein results in increased transport of estrone sulfate]; estrone sulfate inhibits the reaction [SLC10A1 protein results in increased transport of daidzein metabolite]; Taurocholic Acid inhibits the reaction [SLC10A1 protein results in increased transport of daidzein metabolite] CTD PMID:25319728 NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670 		JBrowse link
G Slc10a6 solute carrier family 10 member 6 multiple interactions
increases transport		 ISO daidzein inhibits the reaction [SLC10A6 protein results in increased transport of estrone sulfate]; daidzein metabolite inhibits the reaction [SLC10A6 protein results in increased transport of estrone sulfate]; estrone sulfate inhibits the reaction [SLC10A6 protein results in increased transport of daidzein metabolite] CTD PMID:25319728 NCBI chr14:6,080,716...6,102,902
Ensembl chr14:6,080,717...6,103,037 		JBrowse link
G Slc12a2 solute carrier family 12 member 2 decreases expression ISO daidzein results in decreased expression of SLC12A2 mRNA CTD PMID:15757668 NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440 		JBrowse link
G Slc16a1 solute carrier family 16 member 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SLC16A1 mRNA CTD PMID:27424125 NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611 		JBrowse link
G Slc22a8 solute carrier family 22 member 8 increases uptake ISO SLC22A8 protein results in increased uptake of daidzein analog CTD PMID:21244849 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions
decreases activity		 ISO daidzein inhibits the reaction [SLC2A1 protein affects the transport of Glucose]
daidzein results in decreased activity of SLC2A1 protein		 CTD PMID:14642735 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416 		JBrowse link
G Slc7a5 solute carrier family 7 member 5 increases expression ISO daidzein results in increased expression of SLC7A5 mRNA CTD PMID:15757668 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823 		JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 increases transport
multiple interactions		 ISO SLCO2B1 protein results in increased transport of daidzein metabolite
daidzein inhibits the reaction [SLCO2B1 protein results in increased transport of estrone sulfate]; daidzein metabolite inhibits the reaction [SLCO2B1 protein results in increased transport of estrone sulfate]; estrone sulfate inhibits the reaction [SLCO2B1 protein results in increased transport of daidzein metabolite]		 CTD PMID:25319728 NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353 		JBrowse link
G Snx30 sorting nexin family member 30 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of SNX30 mRNA CTD PMID:27424125 NCBI chr 5:74,683,902...74,813,013
Ensembl chr 5:74,684,015...74,792,631 		JBrowse link
G Sod2 superoxide dismutase 2 increases expression
affects response to substance
multiple interactions		 ISO daidzein results in increased expression of SOD2 protein
SOD2 protein affects the susceptibility to daidzein
fulvestrant inhibits the reaction [daidzein results in increased expression of SOD2 protein]		 CTD PMID:23526725 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Ssc5d scavenger receptor cysteine rich family member with 5 domains multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SSC5D mRNA CTD PMID:27424125 NCBI chr 1:68,891,942...68,910,462
Ensembl chr 1:68,891,949...68,909,743 		JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of STAR mRNA; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of STAR protein CTD PMID:28964809 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO daidzein inhibits the reaction [Lipopolysaccharides affects the localization of and results in increased activity of STAT1 protein alternative form]; daidzein inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT1 protein] CTD PMID:18274639 PMID:21972936 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Stc1 stanniocalcin 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of STC1 mRNA CTD PMID:16963248 NCBI chr15:44,299,591...44,311,695
Ensembl chr15:44,299,621...44,310,264 		JBrowse link
G Stk39 serine threonine kinase 39 decreases expression ISO daidzein results in decreased expression of STK39 mRNA CTD PMID:16865672 NCBI chr 3:52,913,583...53,179,060
Ensembl chr 3:52,913,585...53,179,060 		JBrowse link
G Styxl1 serine/threonine/tyrosine interacting-like 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of STYXL1 mRNA CTD PMID:27424125 NCBI chr12:20,907,410...20,940,232
Ensembl chr12:20,907,435...20,939,752 		JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 multiple interactions ISO daidzein inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol] CTD PMID:15531517 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562 		JBrowse link
G Sumo1 small ubiquitin-like modifier 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of SUMO1 mRNA CTD PMID:27424125 NCBI chr 9:61,078,790...61,108,697
Ensembl chr 9:61,077,435...61,108,761 		JBrowse link
G Tacr3 tachykinin receptor 3 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of TACR3 mRNA CTD PMID:16963248 NCBI chr 2:223,266,536...223,363,791
Ensembl chr 2:223,266,536...223,363,791 		JBrowse link
G Tc2n tandem C2 domains, nuclear multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of TC2N mRNA CTD PMID:27424125 NCBI chr 6:120,761,112...120,856,835
Ensembl chr 6:120,761,119...120,849,326 		JBrowse link
G Tff1 trefoil factor 1 increases expression
multiple interactions		 ISO daidzein results in increased expression of TFF1 mRNA
ESR1 protein inhibits the reaction [daidzein results in increased expression of TFF1 mRNA]		 CTD PMID:16965913 PMID:23384675 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597 		JBrowse link
G Tg thyroglobulin decreases expression EXP daidzein results in decreased expression of TG mRNA CTD PMID:24793811 NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210 		JBrowse link
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 multiple interactions ISO daidzein promotes the reaction [TGFB1I1 protein results in increased activity of AR protein] CTD PMID:17252558 NCBI chr 1:182,828,553...182,835,465
Ensembl chr 1:182,828,544...182,837,080 		JBrowse link
G Tgm2 transglutaminase 2 increases expression ISO daidzein results in increased expression of TGM2 mRNA; daidzein results in increased expression of TGM2 protein CTD PMID:24859791 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981 		JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions
affects binding		 ISO daidzein promotes the reaction [Triiodothyronine results in increased activity of THRA protein]
daidzein binds to THRA protein		 CTD PMID:29688519 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936 		JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO [daidzein binds to THRB protein] promotes the reaction [NCOA1 protein binds to THRB protein]; daidzein promotes the reaction [NCOA1 protein binds to THRB protein]; daidzein promotes the reaction [Triiodothyronine results in increased activity of THRB protein] CTD PMID:29688519 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916 		JBrowse link
G Thrsp thyroid hormone responsive increases expression EXP daidzein results in increased expression of THRSP mRNA CTD PMID:24793811 NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [Genistein co-treated with daidzein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:21945492 PMID:22981962 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfaip6 TNF alpha induced protein 6 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of TNFAIP6 mRNA CTD PMID:16963248 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B multiple interactions
increases expression		 ISO Fulvestrant inhibits the reaction [daidzein results in increased expression of TNFRSF11B mRNA]; Fulvestrant inhibits the reaction [daidzein results in increased expression of TNFRSF11B protein]
daidzein results in increased expression of TNFRSF11B mRNA; daidzein results in increased expression of TNFRSF11B protein		 CTD PMID:27576059 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538 		JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions
decreases expression		 ISO Fulvestrant inhibits the reaction [daidzein results in decreased expression of TNFSF11 mRNA]; Fulvestrant inhibits the reaction [daidzein results in decreased expression of TNFSF11 protein]
daidzein results in decreased expression of TNFSF11 mRNA; daidzein results in decreased expression of TNFSF11 protein		 CTD PMID:27576059 NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Tp53 tumor protein p53 increases expression ISO daidzein results in increased expression of TP53 protein CTD PMID:19800779 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp53i11 tumor protein p53 inducible protein 11 decreases expression
multiple interactions		 ISO daidzein results in decreased expression of TP53I11 mRNA
[daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of TP53I11 mRNA		 CTD PMID:15757668 PMID:27424125 NCBI chr 3:79,144,824...79,160,056
Ensembl chr 3:79,144,895...79,160,050 		JBrowse link
G Tpd52l1 TPD52 like 1 increases expression ISO daidzein results in increased expression of TPD52L1 mRNA CTD PMID:15757668 NCBI chr 1:26,172,038...26,290,704
Ensembl chr 1:26,172,170...26,291,109 		JBrowse link
G Tpo thyroid peroxidase decreases expression
decreases activity		 EXP
ISO		 daidzein results in decreased expression of TPO mRNA
daidzein results in decreased activity of TPO protein		 CTD PMID:24793811 PMID:31629072 NCBI chr 6:46,698,402...46,768,199
Ensembl chr 6:46,698,414...46,768,199 		JBrowse link
G Tyr tyrosinase increases expression ISO daidzein results in increased expression of TYR mRNA CTD PMID:21071833 NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207 		JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of UCHL1 mRNA CTD PMID:16963248 NCBI chr14:41,485,031...41,495,590
Ensembl chr14:41,485,031...41,495,590 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation
increases activity		 ISO UGT1A1 protein results in increased glucuronidation of daidzein
daidzein results in increased activity of UGT1A1 protein		 CTD PMID:14557274 PMID:16051636 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of daidzein CTD PMID:14557274 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 increases expression ISO daidzein results in increased expression of UGT2B17 mRNA CTD PMID:16865672 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO ESR2 gene polymorphism affects the reaction [[Genistein co-treated with daidzein] affects the expression of VCAM1 protein] CTD PMID:16332659 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958 		JBrowse link
G Vcpip1 valosin containing protein interacting protein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of VCPIP1 mRNA CTD PMID:27424125 NCBI chr 5:9,534,247...9,560,889
Ensembl chr 5:9,534,129...9,562,040 		JBrowse link
3',4',7-trihydroxyisoflavone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A decreases expression
multiple interactions		 ISO 3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mRNA
3',4',7-trihydroxyisoflavone inhibits the reaction [Epirubicin results in increased expression of ABCB1 mRNA]; Acetylcysteine inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mRNA]; Ascorbic Acid inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mRNA]; CAT protein inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mRNA]		 CTD PMID:22914566 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
decreases expression		 ISO 3',4',7-trihydroxyisoflavone inhibits the reaction [Epirubicin results in increased expression of ABCC1 mRNA]; Acetylcysteine inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC1 mRNA]; Ascorbic Acid inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC1 mRNA]; CAT protein inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC1 mRNA] CTD PMID:22914566 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions
decreases expression		 ISO 3',4',7-trihydroxyisoflavone inhibits the reaction [Epirubicin results in increased expression of ABCC2 mRNA]; Acetylcysteine inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC2 mRNA]; Ascorbic Acid inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC2 mRNA]; CAT protein inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC2 mRNA] CTD PMID:22914566 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions		 ISO 3',4',7-trihydroxyisoflavone results in increased expression of BAX mRNA
3',4',7-trihydroxyisoflavone promotes the reaction [Epirubicin results in increased expression of BAX mRNA]; Epirubicin promotes the reaction [3',4',7-trihydroxyisoflavone results in increased expression of BAX mRNA]		 CTD PMID:22914566 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
increases expression		 ISO 3',4',7-trihydroxyisoflavone promotes the reaction [Epirubicin results in increased expression of CASP3 mRNA]; Epirubicin promotes the reaction [3',4',7-trihydroxyisoflavone results in increased activity of CASP3 protein]; Epirubicin promotes the reaction [3',4',7-trihydroxyisoflavone results in increased expression of CASP3 mRNA] CTD PMID:22914566 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
increases expression		 ISO 3',4',7-trihydroxyisoflavone promotes the reaction [Epirubicin results in increased expression of CASP9 mRNA]; Epirubicin promotes the reaction [3',4',7-trihydroxyisoflavone results in increased activity of CASP9 protein]; Epirubicin promotes the reaction [3',4',7-trihydroxyisoflavone results in increased expression of CASP9 mRNA] CTD PMID:22914566 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase multiple interactions ISO CAT protein inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mRNA]; CAT protein inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC1 mRNA]; CAT protein inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC2 mRNA] CTD PMID:22914566 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression		 ISO 3',4',7-trihydroxyisoflavone promotes the reaction [Epirubicin results in increased expression of TP53 mRNA]; Epirubicin promotes the reaction [3',4',7-trihydroxyisoflavone results in increased expression of TP53 mRNA] CTD PMID:22914566 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
daidzein 7-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase increases expression
multiple interactions		 EXP daidzin results in increased expression of ACHE mRNA
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [daidzin results in increased expression of ACHE mRNA]; 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [daidzin results in increased expression of and results in increased activity of ACHE protein]; daidzin results in increased expression of and results in increased activity of ACHE protein		 CTD PMID:31034797 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of ACSL3 mRNA CTD PMID:27424125 NCBI chr 9:80,115,164...80,164,636
Ensembl chr 9:80,115,112...80,164,627 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ALDH1A2 mRNA CTD PMID:27424125 NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions ISO daidzin inhibits the reaction [ALDH2 protein results in increased hydrolysis of 4-nitrophenyl acetate]; daidzin inhibits the reaction [ALDH2 protein results in increased oxidation of propionaldehyde] CTD PMID:21349255 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Anpep alanyl aminopeptidase, membrane multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ANPEP mRNA CTD PMID:27424125 NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789 		JBrowse link
G Atoh8 atonal bHLH transcription factor 8 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of ATOH8 mRNA CTD PMID:27424125 NCBI chr 4:104,259,992...104,292,168
Ensembl chr 4:104,259,992...104,292,168 		JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of BCKDK mRNA CTD PMID:27424125 NCBI chr 1:182,515,335...182,520,007
Ensembl chr 1:182,515,327...182,536,633 		JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO daidzin inhibits the reaction [Pentylenetetrazole results in decreased expression of BDNF protein] CTD PMID:32450180 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Bpgm bisphosphoglycerate mutase multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of BPGM mRNA CTD PMID:27424125 NCBI chr 4:63,139,730...63,168,581
Ensembl chr 4:63,140,018...63,168,581 		JBrowse link
G Cabp5 calcium binding protein 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CABP5 mRNA CTD PMID:27424125 NCBI chr 1:74,350,811...74,363,830
Ensembl chr 1:74,350,811...74,363,830 		JBrowse link
G Cacybp calcyclin binding protein multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of CACYBP mRNA CTD PMID:27424125 NCBI chr13:72,437,485...72,447,810
Ensembl chr13:72,437,490...72,450,177 		JBrowse link
G Casp8ap2 caspase 8 associated protein 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CASP8AP2 mRNA CTD PMID:27424125 NCBI chr 5:47,014,501...47,052,276
Ensembl chr 5:47,014,667...47,052,275 		JBrowse link
G Cat catalase multiple interactions ISO daidzin inhibits the reaction [Pentylenetetrazole results in decreased activity of CAT protein] CTD PMID:32450180 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cd200r1 CD200 receptor 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CD200R1 mRNA CTD PMID:27424125 NCBI chr11:55,886,937...55,921,217
Ensembl chr11:55,887,717...55,921,285 		JBrowse link
G Cfap251 cilia and flagella associated protein 251 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of CFAP251 mRNA CTD PMID:27424125 NCBI chr12:33,261,622...33,337,028
Ensembl chr12:33,261,476...33,293,932 		JBrowse link
G Cybrd1 cytochrome b reductase 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CYBRD1 mRNA CTD PMID:27424125 NCBI chr 3:55,934,874...55,962,132
Ensembl chr 3:55,934,874...55,962,108 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of CYP11A1 mRNA CTD PMID:28964809 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Dennd2d DENN domain containing 2D multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of DENND2D mRNA CTD PMID:27424125 NCBI chr 2:193,973,231...193,992,275
Ensembl chr 2:193,973,231...193,992,270 		JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT1 mRNA CTD PMID:28964809 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT3A mRNA CTD PMID:28964809 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Dpp9 dipeptidyl peptidase 9 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of DPP9 mRNA CTD PMID:27424125 NCBI chr 9:1,011,347...1,046,337
Ensembl chr 9:1,011,351...1,046,541 		JBrowse link
G Edrf1 erythroid differentiation regulatory factor 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of EDRF1 mRNA CTD PMID:27424125 NCBI chr 1:188,441,514...188,478,743
Ensembl chr 1:188,441,634...188,478,701 		JBrowse link
G Efhd1 EF-hand domain family, member D1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of EFHD1 mRNA CTD PMID:27424125 NCBI chr 9:87,938,259...87,984,917
Ensembl chr 9:87,938,284...87,984,917 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of ESR2 mRNA CTD PMID:28964809 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Fam171a2 family with sequence similarity 171, member A2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of FAM171A2 mRNA CTD PMID:27424125 NCBI chr10:87,393,888...87,404,051
Ensembl chr10:87,394,007...87,404,053 		JBrowse link
G Fam180a family with sequence similarity 180, member A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FAM180A mRNA CTD PMID:27424125 NCBI chr 4:63,992,867...64,008,047
Ensembl chr 4:63,992,867...64,008,047 		JBrowse link
G Fam210b family with sequence similarity 210, member B multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FAM210B mRNA CTD PMID:27424125 NCBI chr 3:161,118,228...161,128,400
Ensembl chr 3:161,118,239...161,128,397 		JBrowse link
G Fam241b family with sequence similarity 241 member B multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of FAM241B mRNA CTD PMID:27424125 NCBI chr20:30,052,315...30,055,247
Ensembl chr20:30,052,324...30,055,084
Ensembl chr 6:30,052,324...30,055,084 		JBrowse link
G Fgd6 FYVE, RhoGEF and PH domain containing 6 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of FGD6 mRNA CTD PMID:27424125 NCBI chr 7:28,597,609...28,712,908
Ensembl chr 7:28,597,609...28,712,456 		JBrowse link
G Fhl2 four and a half LIM domains 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FHL2 mRNA CTD PMID:27424125 NCBI chr 9:45,388,979...45,462,421
Ensembl chr 9:45,388,981...45,431,192 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO daidzin results in increased expression of FOS mRNA CTD PMID:17142977 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Galnt15 polypeptide N-acetylgalactosaminyltransferase 15 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of GALNT15 mRNA CTD PMID:27424125 NCBI chr16:7,227,232...7,267,002
Ensembl chr16:7,227,271...7,267,014 		JBrowse link
G Gng5 G protein subunit gamma 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of GNG5 mRNA CTD PMID:27424125 NCBI chr 2:235,394,680...235,403,177
Ensembl chr 1:77,292,043...77,292,513
Ensembl chr11:77,292,043...77,292,513 		JBrowse link
G Hipk4 homeodomain interacting protein kinase 4 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of HIPK4 mRNA CTD PMID:27424125 NCBI chr 1:82,810,708...82,821,080
Ensembl chr 1:82,810,708...82,821,077 		JBrowse link
G Hmcn1 hemicentin 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of HMCN1 mRNA CTD PMID:27424125 NCBI chr13:62,615,461...63,084,524
Ensembl chr13:62,615,461...63,084,524 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO daidzin inhibits the reaction [Pentylenetetrazole results in decreased expression of HMOX1 protein] CTD PMID:32450180 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of HSD3B1 mRNA CTD PMID:28964809 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Il6r interleukin 6 receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of IL6R mRNA CTD PMID:27424125 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536 		JBrowse link
G Isg20l2 interferon stimulated exonuclease gene 20-like 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ISG20L2 mRNA CTD PMID:27424125 NCBI chr 2:173,396,780...173,407,102
Ensembl chr 2:173,396,780...173,406,614 		JBrowse link
G Kdm5a lysine demethylase 5A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of KDM5A mRNA CTD PMID:27424125 NCBI chr 4:153,565,909...153,643,912
Ensembl chr 4:153,565,846...153,642,422 		JBrowse link
G Kitlg KIT ligand multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of KITLG mRNA CTD PMID:27424125 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214 		JBrowse link
G Knstrn kinetochore-localized astrin/SPAG5 binding protein multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of KNSTRN mRNA CTD PMID:27424125 NCBI chr 3:105,800,762...105,820,555
Ensembl chr 3:105,800,954...105,820,715 		JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LDLRAP1 mRNA CTD PMID:27424125 NCBI chr 5:146,955,607...146,978,601
Ensembl chr 5:146,955,607...146,978,601 		JBrowse link
G Lmod1 leiomodin 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LMOD1 mRNA CTD PMID:27424125 NCBI chr13:46,754,048...46,796,186
Ensembl chr13:46,754,033...46,794,900 		JBrowse link
G Lrg1 leucine-rich alpha-2-glycoprotein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of LRG1 mRNA CTD PMID:27424125 NCBI chr 9:947,516...949,773
Ensembl chr 9:947,516...949,813 		JBrowse link
G Lsr lipolysis stimulated lipoprotein receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LSR mRNA CTD PMID:27424125 NCBI chr 1:86,185,769...86,201,952
Ensembl chr 1:86,186,431...86,201,952 		JBrowse link
G Mrpl33 mitochondrial ribosomal protein L33 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of MRPL33 mRNA CTD PMID:27424125 NCBI chr 6:24,825,800...24,833,994
Ensembl chr 6:24,825,827...24,833,834 		JBrowse link
G Mtmr11 myotubularin related protein 11 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of MTMR11 mRNA CTD PMID:27424125 NCBI chr 2:183,721,983...183,732,148
Ensembl chr 2:183,723,530...183,732,148 		JBrowse link
G Myof myoferlin multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of MYOF mRNA CTD PMID:27424125 NCBI chr 1:235,673,666...235,822,413
Ensembl chr 1:235,673,666...235,822,334 		JBrowse link
G Nefh neurofilament heavy chain increases expression EXP daidzin results in increased expression of NEFH mRNA; daidzin results in increased expression of NEFH protein CTD PMID:31034797 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351 		JBrowse link
G Nefl neurofilament light chain increases expression EXP daidzin results in increased expression of NEFL mRNA; daidzin results in increased expression of NEFL protein CTD PMID:31034797 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793 		JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of NR4A1 mRNA CTD PMID:27424125 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297 		JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 mRNA; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 protein; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased methylation of NR5A1 promoter; decitabine inhibits the reaction [[Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 mRNA] CTD PMID:28964809 NCBI chr 3:22,464,786...22,486,328
Ensembl chr 3:22,465,502...22,486,328 		JBrowse link
G Pgr progesterone receptor increases expression ISO daidzin results in increased expression of PGR protein CTD PMID:17142977 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
G Prima1 proline rich membrane anchor 1 increases expression
multiple interactions		 EXP daidzin results in increased expression of PRIMA1 mRNA
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [daidzin results in increased expression of PRIMA1 mRNA]		 CTD PMID:31034797 NCBI chr 6:122,338,365...122,390,955
Ensembl chr 6:122,338,370...122,389,921 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of PRKACA mRNA CTD PMID:27424125 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430 		JBrowse link
G Prpf40a pre-mRNA processing factor 40 homolog A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of PRPF40A mRNA CTD PMID:27424125 NCBI chr 3:37,625,585...37,689,859
Ensembl chr 3:37,627,690...37,690,886 		JBrowse link
G Pspc1 paraspeckle component 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of PSPC1 mRNA CTD PMID:27424125 NCBI chr15:30,828,617...30,911,315
Ensembl chr15:30,828,626...30,911,202 		JBrowse link
G Pth1r parathyroid hormone 1 receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of PTH1R mRNA CTD PMID:27424125 NCBI chr 8:110,693,910...110,725,458
Ensembl chr 8:110,697,485...110,719,729 		JBrowse link
G Rassf5 Ras association domain family member 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of RASSF5 mRNA CTD PMID:27424125 NCBI chr13:42,637,513...42,703,024
Ensembl chr13:42,637,549...42,703,024 		JBrowse link
G Rgs22 regulator of G-protein signaling 22 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of RGS22 mRNA CTD PMID:27424125 NCBI chr 7:67,188,531...67,308,805
Ensembl chr 7:67,188,519...67,308,875 		JBrowse link
G S1pr3 sphingosine-1-phosphate receptor 3 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of S1PR3 mRNA CTD PMID:27424125 NCBI chr17:13,781,050...13,794,408
Ensembl chr17:13,781,050...13,794,505 		JBrowse link
G Selplg selectin P ligand multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SELPLG mRNA CTD PMID:27424125 NCBI chr12:42,796,690...42,809,908
Ensembl chr12:42,796,580...42,812,585 		JBrowse link
G Siglec10 sialic acid binding Ig-like lectin 10 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of SIGLEC10 mRNA CTD PMID:27424125 NCBI chr 1:93,817,301...93,826,376
Ensembl chr 1:93,817,335...93,825,931 		JBrowse link
G Slc16a1 solute carrier family 16 member 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SLC16A1 mRNA CTD PMID:27424125 NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611 		JBrowse link
G Snx30 sorting nexin family member 30 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of SNX30 mRNA CTD PMID:27424125 NCBI chr 5:74,683,902...74,813,013
Ensembl chr 5:74,684,015...74,792,631 		JBrowse link
G Ssc5d scavenger receptor cysteine rich family member with 5 domains multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SSC5D mRNA CTD PMID:27424125 NCBI chr 1:68,891,942...68,910,462
Ensembl chr 1:68,891,949...68,909,743 		JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of STAR mRNA; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of STAR protein CTD PMID:28964809 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Styxl1 serine/threonine/tyrosine interacting-like 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of STYXL1 mRNA CTD PMID:27424125 NCBI chr12:20,907,410...20,940,232
Ensembl chr12:20,907,435...20,939,752 		JBrowse link
G Sumo1 small ubiquitin-like modifier 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of SUMO1 mRNA CTD PMID:27424125 NCBI chr 9:61,078,790...61,108,697
Ensembl chr 9:61,077,435...61,108,761 		JBrowse link
G Tc2n tandem C2 domains, nuclear multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of TC2N mRNA CTD PMID:27424125 NCBI chr 6:120,761,112...120,856,835
Ensembl chr 6:120,761,119...120,849,326 		JBrowse link
G Tp53i11 tumor protein p53 inducible protein 11 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of TP53I11 mRNA CTD PMID:27424125 NCBI chr 3:79,144,824...79,160,056
Ensembl chr 3:79,144,895...79,160,050 		JBrowse link
G Vcpip1 valosin containing protein interacting protein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of VCPIP1 mRNA CTD PMID:27424125 NCBI chr 5:9,534,247...9,560,889
Ensembl chr 5:9,534,129...9,562,040 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO daidzin inhibits the reaction [Pentylenetetrazole results in increased expression of VEGFA protein] CTD PMID:32450180 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
formononetin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
decreases activity
increases expression
affects activity		 ISO Acetylcysteine inhibits the reaction [formononetin results in increased expression of ABCB1 mRNA]; formononetin inhibits the reaction [Epirubicin results in increased expression of ABCB1 mRNA]; formononetin promotes the reaction [Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]]
formononetin results in decreased activity of ABCB1 protein
formononetin affects the activity of ABCB1 protein		 CTD PMID:15796199 PMID:23867903 PMID:27996361 PMID:34217736 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 affects activity
decreases expression
multiple interactions		 ISO formononetin affects the activity of ABCC1 protein
formononetin results in decreased expression of ABCC1 mRNA
Acetylcysteine inhibits the reaction [formononetin results in decreased expression of ABCC1 mRNA]; formononetin inhibits the reaction [Epirubicin results in increased expression of ABCC1 mRNA]		 CTD PMID:15796199 PMID:23867903 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions
decreases expression		 ISO
EXP		 Acetylcysteine inhibits the reaction [formononetin results in decreased expression of ABCC2 mRNA]; formononetin inhibits the reaction [Epirubicin results in increased expression of ABCC2 mRNA]
formononetin promotes the reaction [Cisplatin results in increased expression of ABCC2 mRNA]		 CTD PMID:23867903 PMID:28414026 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions EXP formononetin promotes the reaction [Cisplatin results in increased expression of ABCC4 mRNA] CTD PMID:28414026 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283 		JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant multiple interactions ISO formononetin inhibits the reaction [Streptozocin results in increased activity of ACP5 protein]; formononetin inhibits the reaction [Streptozocin results in increased expression of ACP5 mRNA] CTD PMID:35315182 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
increases activity		 ISO fulvestrant promotes the reaction [formononetin results in increased activity of AHR protein] CTD PMID:28985473 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO formononetin results in increased expression of AKR1B10 mRNA CTD PMID:37793997 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases phosphorylation		 ISO formononetin promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of AKT1 protein]; Wortmannin inhibits the reaction [formononetin promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of AKT1 protein]]
formononetin decreases phosphorylation of AKT1 protein in lung 		CTD
RGD		 PMID:34077701 PMID:32276600 RGD:151357000 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO
EXP		 formononetin promotes the reaction [Epirubicin results in increased expression of BAX mRNA]
formononetin inhibits the reaction [Cisplatin results in increased expression of BAX protein]		 CTD PMID:23867903 PMID:28414026 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions		 ISO
EXP		 formononetin results in decreased expression of BCL2 mRNA
formononetin inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein]
formononetin promotes the reaction [Cisplatin results in increased expression of BCL2 protein]		 CTD PMID:23867903 PMID:28414026 PMID:34077701 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
increases expression		 ISO
EXP		 Acetylcysteine inhibits the reaction [formononetin results in increased expression of CASP3 mRNA]; Epirubicin promotes the reaction [formononetin results in increased activity of CASP3 protein]; Epirubicin promotes the reaction [formononetin results in increased expression of CASP3 mRNA]; formononetin inhibits the reaction [Hydrogen Peroxide results in increased cleavage of CASP3 protein]; formononetin promotes the reaction [Epirubicin results in increased activity of CASP3 protein]; formononetin promotes the reaction [Epirubicin results in increased expression of CASP3 mRNA]
formononetin increases activity of CASP3 protein in lung
formononetin inhibits the reaction [Cisplatin results in increased expression of CASP3 protein modified form]		 CTD
RGD		 PMID:23867903 PMID:28414026 PMID:34077701 PMID:32276600 RGD:151357000 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp7 caspase 7 multiple interactions ISO formononetin inhibits the reaction [Hydrogen Peroxide results in increased cleavage of CASP7 protein] CTD PMID:34077701 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Casp8 caspase 8 multiple interactions
increases expression
increases activity		 ISO Acetylcysteine inhibits the reaction [formononetin results in increased expression of CASP8 mRNA]; Epirubicin promotes the reaction [formononetin results in increased activity of CASP8 protein]; Epirubicin promotes the reaction [formononetin results in increased expression of CASP8 mRNA] CTD PMID:23867903 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
increases activity		 ISO Acetylcysteine inhibits the reaction [formononetin results in increased expression of CASP9 mRNA]; Epirubicin promotes the reaction [formononetin results in increased activity of CASP9 protein]; Epirubicin promotes the reaction [formononetin results in increased expression of CASP9 mRNA]; formononetin promotes the reaction [Epirubicin results in increased activity of CASP9 protein]; formononetin promotes the reaction [Epirubicin results in increased expression of CASP9 mRNA] CTD PMID:23867903 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Ccnb1 cyclin B1 increases expression
multiple interactions		 ISO
EXP		 formononetin results in increased expression of CCNB1 protein
XI-006 inhibits the reaction [formononetin results in increased expression of CCNB1 protein]		 CTD PMID:28414026 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccnd1 cyclin D1 increases expression
multiple interactions		 EXP
ISO		 formononetin results in increased expression of CCND1 protein
XI-006 inhibits the reaction [formononetin results in increased expression of CCND1 protein]		 CTD PMID:28414026 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression ISO formononetin results in increased expression of CPT1A mRNA CTD PMID:37793997 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Ctsk cathepsin K multiple interactions ISO formononetin inhibits the reaction [Streptozocin results in increased expression of CTSK mRNA]; formononetin inhibits the reaction [Streptozocin results in increased expression of CTSK protein] CTD PMID:35315182 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases hydroxylation
increases expression
multiple interactions
decreases methylation		 ISO CYP1A1 protein results in increased hydroxylation of formononetin
formononetin results in increased expression of CYP1A1 mRNA
fulvestrant promotes the reaction [formononetin results in increased expression of CYP1A1 mRNA]
CYP1A1 protein results in decreased methylation of formononetin		 CTD PMID:15479032 PMID:28985473 PMID:37793997 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO
EXP		 formononetin results in decreased activity of CYP1A2 protein CTD PMID:26278343 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases methylation
increases expression		 ISO CYP1B1 protein results in decreased methylation of formononetin
formononetin results in increased expression of CYP1B1 mRNA		 CTD PMID:15479032 PMID:28985473 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO formononetin results in decreased activity of CYP2D6 protein CTD PMID:26278343 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Egfr epidermal growth factor receptor decreases phosphorylation ISO formononetin decreases phosphorylation of EGFR protein in lung RGD PMID:32276600 RGD:151357000 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Epo erythropoietin increases expression ISO formononetin results in increased expression of EPO mRNA CTD PMID:21309574 PMID:37348668 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946 		JBrowse link
G Esr1 estrogen receptor 1 affects binding
multiple interactions		 ISO formononetin binds to ESR1 protein
[Lipopolysaccharides co-treated with formononetin] results in increased expression of ESR1 protein
formononetin binds to and results in increased activity of ESR1 protein		 CTD PMID:9751507 PMID:16076101 PMID:16773531 PMID:37269934 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
affects binding		 ISO formononetin binds to and results in increased activity of ESR2 protein
formononetin binds to ESR2 protein		 CTD PMID:9751507 PMID:12224631 PMID:16076101 PMID:16773531 PMID:19913605 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO formononetin inhibits the reaction [Streptozocin results in increased expression of FOS mRNA]; formononetin inhibits the reaction [Streptozocin results in increased expression of FOS protein] CTD PMID:35315182 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions ISO [formononetin co-treated with Hydrogen Peroxide] results in increased expression of GCLM protein; formononetin promotes the reaction [Hydrogen Peroxide results in increased expression of GCLM mRNA]; NFE2L2 protein affects the reaction [formononetin promotes the reaction [Hydrogen Peroxide results in increased expression of GCLM mRNA]]; Wortmannin inhibits the reaction [formononetin promotes the reaction [Hydrogen Peroxide results in increased expression of GCLM mRNA]] CTD PMID:34077701 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions EXP formononetin inhibits the reaction [Cisplatin results in increased expression of HAVCR1 mRNA] CTD PMID:28414026 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression
multiple interactions		 ISO formononetin results in increased expression of HIF1A mRNA; formononetin results in increased expression of HIF1A protein
formononetin results in decreased degradation of and results in increased expression of HIF1A protein modified form; formononetin results in increased expression of and results in decreased degradation of HIF1A protein		 CTD PMID:21309574 PMID:37348668 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO
EXP		 [formononetin co-treated with Hydrogen Peroxide] results in increased expression of HMOX1 protein; formononetin promotes the reaction [Hydrogen Peroxide results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [formononetin promotes the reaction [Hydrogen Peroxide results in increased expression of HMOX1 mRNA]]; Wortmannin inhibits the reaction [formononetin promotes the reaction [Hydrogen Peroxide results in increased expression of HMOX1 mRNA]]
formononetin inhibits the reaction [Glucose results in decreased expression of HMOX1 mRNA]		 CTD PMID:34077701 PMID:37944786 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Il17a interleukin 17A multiple interactions ISO formononetin promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA] CTD PMID:25583575 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889 		JBrowse link
G Il4 interleukin 4 increases expression ISO formononetin results in increased expression of IL4 mRNA; formononetin results in increased expression of IL4 protein CTD PMID:16108819 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO formononetin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] CTD PMID:37269934 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO formononetin inhibits the reaction [Streptozocin results in increased expression of JUN mRNA]; formononetin inhibits the reaction [Streptozocin results in increased expression of JUN protein] CTD PMID:35315182 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO formononetin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein] CTD PMID:34077701 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO formononetin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein] CTD PMID:34077701 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO formononetin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] CTD PMID:34077701 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Matn3 matrilin 3 decreases expression ISO formononetin results in decreased expression of MATN3 mRNA CTD PMID:37793997 NCBI chr 6:31,748,517...31,768,564
Ensembl chr 6:31,748,474...31,768,101 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression ISO formononetin decreases expression of MCL1 protein in lung RGD PMID:32276600 RGD:151357000 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression EXP formononetin results in increased expression of MDM2 protein CTD PMID:28414026 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mdm4 MDM4 regulator of p53 increases expression EXP formononetin results in increased expression of MDM4 protein CTD PMID:28414026 NCBI chr13:44,432,596...44,516,165
Ensembl chr13:44,406,213...44,474,226 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO formononetin inhibits the reaction [Streptozocin results in increased expression of MMP9 mRNA]; formononetin inhibits the reaction [Streptozocin results in increased expression of MMP9 protein] CTD PMID:35315182 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 multiple interactions ISO formononetin inhibits the reaction [Streptozocin results in increased expression of NFATC1 mRNA]; formononetin inhibits the reaction [Streptozocin results in increased expression of NFATC1 protein] CTD PMID:35315182 NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO [formononetin co-treated with Hydrogen Peroxide] results in increased expression of NFE2L2 mRNA; formononetin promotes the reaction [Hydrogen Peroxide affects the localization of NFE2L2 protein]; NFE2L2 protein affects the reaction [[formononetin co-treated with Hydrogen Peroxide] results in increased expression of NQO1 mRNA]; NFE2L2 protein affects the reaction [[formononetin co-treated with Hydrogen Peroxide] results in increased expression of TXNRD1 mRNA]; NFE2L2 protein affects the reaction [formononetin promotes the reaction [Hydrogen Peroxide results in increased expression of GCLM mRNA]]; NFE2L2 protein affects the reaction [formononetin promotes the reaction [Hydrogen Peroxide results in increased expression of HMOX1 mRNA]]; Wortmannin inhibits the reaction [formononetin promotes the reaction [Hydrogen Peroxide affects the localization of NFE2L2 protein]]
formononetin inhibits the reaction [Lipopolysaccharides results in decreased expression of NFE2L2 mRNA]; formononetin inhibits the reaction [Lipopolysaccharides results in decreased expression of NFE2L2 protein]		 CTD PMID:34077701 PMID:37269934 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO formononetin inhibits the reaction [CXCL8 protein results in increased phosphorylation of NFKBIA protein] CTD PMID:22387535 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Ngf nerve growth factor multiple interactions EXP formononetin inhibits the reaction [Glucose results in decreased expression of NGF mRNA]; formononetin inhibits the reaction [Glucose results in decreased secretion of and results in decreased expression of NGF protein] CTD PMID:37944786 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO formononetin inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 mRNA] CTD PMID:37269934 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nos3 nitric oxide synthase 3 increases expression
multiple interactions		 EXP formononetin results in increased expression of NOS3 mRNA
formononetin results in increased phosphorylation of and results in increased activity of NOS3 protein		 CTD PMID:19570671 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [formononetin co-treated with Hydrogen Peroxide] results in increased expression of NQO1 mRNA; [formononetin co-treated with Hydrogen Peroxide] results in increased expression of NQO1 protein; NFE2L2 protein affects the reaction [[formononetin co-treated with Hydrogen Peroxide] results in increased expression of NQO1 mRNA]; Wortmannin inhibits the reaction [[formononetin co-treated with Hydrogen Peroxide] results in increased expression of NQO1 mRNA] CTD PMID:34077701 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Pgc progastricsin decreases expression ISO formononetin results in decreased expression of PGC mRNA CTD PMID:37793997 NCBI chr 9:13,257,462...13,265,682
Ensembl chr 9:13,257,462...13,265,682 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions EXP formononetin inhibits the reaction [Glucose results in decreased expression of PPARGC1A mRNA]; formononetin inhibits the reaction [Glucose results in decreased expression of PPARGC1A protein] CTD PMID:37944786 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 increases phosphorylation
multiple interactions		 ISO formononetin results in increased phosphorylation of PRKAA1 protein
Lipopolysaccharides promotes the reaction [formononetin results in increased phosphorylation of PRKAA1 protein]		 CTD PMID:37269934 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978 		JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 multiple interactions
increases phosphorylation		 ISO Lipopolysaccharides promotes the reaction [formononetin results in increased phosphorylation of PRKAA2 protein] CTD PMID:37269934 NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543 		JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta multiple interactions ISO [Lipopolysaccharides co-treated with formononetin] results in increased phosphorylation of PRKACB protein CTD PMID:37269934 NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198 		JBrowse link
G Ptgr1 prostaglandin reductase 1 increases expression ISO [Formononetin cotreated with gallic acid] increases expression of PTGR1 mRNA in hepatocellular carcinoma cells RGD PMID:26265982 RGD:401959214 NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO formononetin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] CTD PMID:37269934 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Sirt1 sirtuin 1 multiple interactions EXP formononetin inhibits the reaction [Glucose results in decreased expression of SIRT1 mRNA]; formononetin inhibits the reaction [Glucose results in decreased expression of SIRT1 protein] CTD PMID:37944786 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Sirt3 sirtuin 3 affects binding
multiple interactions		 EXP formononetin binds to SIRT3 protein
formononetin inhibits the reaction [Glucose results in decreased expression of SIRT3 mRNA]; formononetin inhibits the reaction [Glucose results in decreased expression of SIRT3 protein]		 CTD PMID:37944786 NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 decreases expression EXP formononetin results in decreased expression of SLC22A2 mRNA CTD PMID:28414026 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Slc6a14 solute carrier family 6 member 14 decreases expression ISO formononetin results in decreased expression of SLC6A14 mRNA CTD PMID:37793997 NCBI chr  X:112,314,643...112,375,412
Ensembl chr  X:112,314,691...112,375,096 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP formononetin inhibits the reaction [Glucose results in decreased expression of SOD1 mRNA]; formononetin inhibits the reaction [Glucose results in decreased expression of SOD1 protein] CTD PMID:37944786 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP formononetin inhibits the reaction [Glucose results in decreased expression of SOD2 mRNA]; formononetin inhibits the reaction [Glucose results in decreased expression of SOD2 protein] CTD PMID:37944786 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Stk11 serine/threonine kinase 11 multiple interactions ISO [Lipopolysaccharides co-treated with formononetin] results in increased phosphorylation of STK11 protein CTD PMID:37269934 NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315 		JBrowse link
G Tagln transgelin decreases expression ISO formononetin results in decreased expression of TAGLN mRNA CTD PMID:37793997 NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668 		JBrowse link
G Tfam transcription factor A, mitochondrial multiple interactions EXP formononetin inhibits the reaction [Glucose results in decreased expression of TFAM mRNA] CTD PMID:37944786 NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292 		JBrowse link
G Tfb2m transcription factor B2, mitochondrial multiple interactions EXP formononetin inhibits the reaction [Glucose results in decreased expression of TFB2M mRNA] CTD PMID:37944786 NCBI chr13:91,278,889...91,296,709
Ensembl chr13:91,278,898...91,296,657 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO formononetin inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein] CTD PMID:37269934 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tp53 tumor protein p53 multiple interactions
decreases expression		 EXP
ISO		 formononetin inhibits the reaction [Cisplatin results in increased expression of TP53 protein]
formononetin results in decreased expression of TP53 protein
XI-006 inhibits the reaction [formononetin results in decreased expression of TP53 protein]		 CTD PMID:28414026 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Trpv5 transient receptor potential cation channel, subfamily V, member 5 multiple interactions ISO formononetin inhibits the reaction [Streptozocin results in decreased expression of TRPV5 mRNA] CTD PMID:35315182 NCBI chr 4:70,536,432...70,562,743
Ensembl chr 4:70,536,440...70,562,745 		JBrowse link
G Trpv6 transient receptor potential cation channel, subfamily V, member 6 multiple interactions ISO formononetin inhibits the reaction [Streptozocin results in decreased expression of TRPV6 mRNA] CTD PMID:35315182 NCBI chr 4:70,507,347...70,523,013
Ensembl chr 4:70,507,348...70,523,017 		JBrowse link
G Txnip thioredoxin interacting protein increases expression ISO formononetin results in increased expression of TXNIP mRNA CTD PMID:37793997 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886 		JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions ISO [formononetin co-treated with Hydrogen Peroxide] results in increased expression of TXNRD1 mRNA; [formononetin co-treated with Hydrogen Peroxide] results in increased expression of TXNRD1 protein; NFE2L2 protein affects the reaction [[formononetin co-treated with Hydrogen Peroxide] results in increased expression of TXNRD1 mRNA]; Wortmannin inhibits the reaction [[formononetin co-treated with Hydrogen Peroxide] results in increased expression of TXNRD1 mRNA] CTD PMID:34077701 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation
increases expression		 ISO UGT1A1 protein results in increased glucuronidation of formononetin
formononetin results in increased expression of UGT1A1 mRNA		 CTD PMID:14557274 PMID:37793997 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of formononetin CTD PMID:14557274 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    role 19850
      application 19695
        pharmaceutical 19532
          drug 19532
            antineoplastic agent 17823
              daidzein 281
                2'-hydroxy-2,3-dihydrodaidzein 0
                2'-hydroxydaidzein 0
                3',4',7-trihydroxyisoflavone 8
                4',6,7-trihydroxyisoflavone 0
                8-prenyldaidzein 0
                daidzein 7-(6-O-acetyl-beta-D-glucoside) 0
                daidzein 7-O-beta-D-glucoside + 74
                daidzein monosulfate 0
                formononetin + 75
                isoformononetin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      carbon group element atom 19757
                        carbon atom 19754
                          organic molecular entity 19754
                            organic molecule 19706
                              organic cyclic compound 19495
                                organic heterocyclic compound 18874
                                  oxacycle 17906
                                    benzopyran 11972
                                      1-benzopyran 11726
                                        isoflavonoid 3827
                                          isoflavones 3808
                                            hydroxyisoflavone 3741
                                              7-hydroxyisoflavones 3719
                                                daidzein 281
                                                  2'-hydroxy-2,3-dihydrodaidzein 0
                                                  2'-hydroxydaidzein 0
                                                  3',4',7-trihydroxyisoflavone 8
                                                  4',6,7-trihydroxyisoflavone 0
                                                  8-prenyldaidzein 0
                                                  daidzein 7-(6-O-acetyl-beta-D-glucoside) 0
                                                  daidzein 7-O-beta-D-glucoside + 74
                                                  daidzein monosulfate 0
                                                  formononetin + 75
                                                  isoformononetin 0
paths to the root