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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:24,25-dihydrolanosterol
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Accession:CHEBI:28113 term browser browse the term
Definition:A 3beta-sterol formed from lanosterol by reduction across the C-24-C-25 double bond.
Synonyms:exact_synonym: lanost-8-en-3beta-ol
 related_synonym: Formula=C30H52O;   InChI=1S/C30H52O/c1-20(2)10-9-11-21(3)22-14-18-30(8)24-12-13-25-27(4,5)26(31)16-17-28(25,6)23(24)15-19-29(22,30)7/h20-22,25-26,31H,9-19H2,1-8H3/t21-,22-,25+,26+,28-,29-,30+/m1/s1;   InChIKey=MBZYKEVPFYHDOH-BQNIITSRSA-N;   Lanostenol;   SMILES=[H][C@@]1(CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]1(C)CC[C@H](O)C(C)(C)[C@]1([H])CC3)[C@H](C)CCCC(C)C
 alt_id: CHEBI:1303;   CHEBI:19807
 xref: Beilstein:2224904;   CAS:79-62-9;   HMDB:HMDB0006839;   KEGG:C05109;   KNApSAcK:C00023781;   LIPID_MAPS_instance:LMST01010087
 xref_mesh: MESH:C015316
 xref: MetaCyc:CPD-8606;   PMID:898228;   Reaxys:2224904


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24,25-dihydrolanosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp51 cytochrome P450, family 51 decreases abundance ISO CYP51A1 mRNA results in decreased abundance of lanostenol CTD PMID:23125191 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases activity ISO lanostenol results in decreased activity of HMGCR protein CTD PMID:18024962 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19917
    role 19887
      biological role 19885
        biochemical role 19569
          metabolite 19577
            eukaryotic metabolite 19378
              plant metabolite 17999
                lanosterol 7
                  24,25-dihydrolanosterol 2
                    eburicol + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19917
    subatomic particle 19915
      composite particle 19915
        hadron 19915
          baryon 19915
            nucleon 19915
              atomic nucleus 19915
                atom 19915
                  main group element atom 19855
                    p-block element atom 19855
                      carbon group element atom 19774
                        carbon atom 19790
                          organic molecular entity 19790
                            organic molecule 19743
                              organic cyclic compound 19533
                                organic polycyclic compound 17311
                                  steroid 14726
                                    hydroxy steroid 14473
                                      3-hydroxy steroid 12810
                                        sterol 467
                                          3beta-sterol 461
                                            lanosterol 7
                                              24,25-dihydrolanosterol 2
                                                eburicol + 0
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