|
|
| G
|
A1bg
|
alpha-1-B glycoprotein
|
affects binding
|
ISO
|
A1BG protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr 7:94,383,333...94,387,922
Ensembl chr 7:94,383,333...94,387,496
|
|
| G
|
A2m
|
alpha-2-macroglobulin
|
affects binding
|
ISO
|
A2M protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr 4:156,570,163...156,619,870
Ensembl chr 4:156,569,860...156,619,868
|
|
| G
|
Aacs
|
acetoacetyl-CoA synthetase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of AACS mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr12:36,774,471...36,817,835
Ensembl chr12:36,774,471...36,822,543
|
|
| G
|
Aamdc
|
adipogenesis associated, Mth938 domain containing
|
decreases expression
|
ISO
|
Nickel results in decreased expression of AAMDC mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:161,273,205...161,303,253
Ensembl chr 1:161,262,347...161,299,340
|
|
| G
|
Aamp
|
angio-associated, migratory cell protein
|
decreases expression
|
ISO
|
Nickel results in decreased expression of AAMP mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 9:83,312,519...83,318,325
Ensembl chr 9:83,312,519...83,318,325
|
|
| G
|
Aars1
|
alanyl-tRNA synthetase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of AARS1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr19:55,906,694...55,930,499
Ensembl chr19:55,906,702...55,930,497
|
|
| G
|
Abca13
|
ATP binding cassette subfamily A member 13
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ABCA13 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr14:88,087,146...88,589,868
Ensembl chr14:88,087,801...88,589,392
|
|
| G
|
Abca3
|
ATP binding cassette subfamily A member 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ABCA3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:13,886,948...13,944,286
Ensembl chr10:13,887,083...13,944,285
|
|
| G
|
Abca6
|
ATP binding cassette subfamily A member 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ABCA6 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr10:95,642,026...95,711,535
Ensembl chr10:95,641,900...95,710,899
|
|
| G
|
Abca8
|
ATP binding cassette subfamily A member 8
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ABCA8 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:95,416,984...95,490,647
Ensembl chr10:95,416,205...95,490,452
|
|
| G
|
Abca9
|
ATP binding cassette subfamily A member 9
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ABCA9 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:95,577,079...95,638,706
Ensembl chr10:95,578,350...95,636,405
|
|
| G
|
Abcb1a
|
ATP binding cassette subfamily B member 1A
|
multiple interactions decreases expression
|
ISO
|
Nickel inhibits the reaction [Magnesium results in increased activity of ABCB1 protein] Nickel results in decreased expression of ABCB1 mRNA
|
CTD |
PMID:2900677 PMID:25583101 |
|
NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
|
|
| G
|
Abcc1
|
ATP binding cassette subfamily C member 1
|
increases expression
|
ISO
|
Nickel results in increased expression of ABCC1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404
|
|
| G
|
Abcc6
|
ATP binding cassette subfamily C member 6
|
multiple interactions decreases expression
|
EXP ISO
|
Nickel promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]; Nickel promotes the reaction [beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]] Nickel results in decreased expression of ABCC6 mRNA
|
CTD |
PMID:12069597 PMID:25583101 |
|
NCBI chr 1:105,583,681...105,637,895
Ensembl chr 1:105,583,682...105,637,895
|
|
| G
|
Abcd3
|
ATP binding cassette subfamily D member 3
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of ABCD3 mRNA Nickel results in increased expression of ABCD3 mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr 2:212,536,791...212,590,379
Ensembl chr 2:212,536,791...212,590,504
|
|
| G
|
Abcf2
|
ATP binding cassette subfamily F member 2
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of ABCF2 mRNA Nickel results in increased expression of ABCF2 mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 4:11,485,865...11,500,067
Ensembl chr 4:11,487,395...11,500,053
|
|
| G
|
Abcg1
|
ATP binding cassette subfamily G member 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ABCG1 mRNA
|
CTD |
PMID:12540486 PMID:24768652 PMID:25583101 |
|
NCBI chr20:9,128,056...9,184,312
Ensembl chr20:9,127,803...9,186,563
|
|
| G
|
Abhd5
|
abhydrolase domain containing 5, lysophosphatidic acid acyltransferase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ABHD5 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 8:130,877,834...130,903,947
Ensembl chr 8:130,877,703...130,903,947
|
|
| G
|
Abi3
|
ABI family, member 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ABI3 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr10:81,266,571...81,277,561
Ensembl chr10:81,266,571...81,277,561
|
|
| G
|
Abl2
|
ABL proto-oncogene 2, non-receptor tyrosine kinase
|
increases expression
|
ISO
|
Nickel results in increased expression of ABL2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:71,223,902...71,319,770
Ensembl chr13:71,224,019...71,389,775
|
|
| G
|
Ablim3
|
actin binding LIM protein family, member 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ABLIM3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr18:57,527,917...57,646,936
Ensembl chr18:57,527,917...57,646,710
|
|
| G
|
Acaa2
|
acetyl-CoA acyltransferase 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ACAA2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr18:70,620,310...70,648,417
Ensembl chr18:70,620,110...70,648,420
|
|
| G
|
Acacb
|
acetyl-CoA carboxylase beta
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ACACB mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr12:48,026,394...48,138,214
Ensembl chr12:48,026,394...48,138,214
|
|
| G
|
Acadl
|
acyl-CoA dehydrogenase, long chain
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ACADL mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:75,783,689...75,822,077
Ensembl chr 9:75,783,689...75,822,164
|
|
| G
|
Acadm
|
acyl-CoA dehydrogenase medium chain
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ACADM mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 2:245,518,693...245,542,864
Ensembl chr 2:245,518,693...245,542,864
|
|
| G
|
Acap1
|
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
|
increases expression
|
ISO
|
Nickel results in increased expression of ACAP1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:55,104,040...55,119,280
Ensembl chr10:55,104,040...55,118,185
|
|
| G
|
Acat2
|
acetyl-CoA acetyltransferase 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ACAT2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 1:50,100,840...50,118,886
Ensembl chr 1:50,100,817...50,135,095
|
|
| G
|
Accs
|
1-aminocyclopropane-1-carboxylate synthase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ACCS mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:100,261,940...100,276,400
Ensembl chr 3:100,261,941...100,296,514
|
|
| G
|
Ace2
|
angiotensin converting enzyme 2
|
increases expression
|
ISO
|
Nickel results in increased expression of ACE2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr X:33,925,458...33,972,851
Ensembl chr X:33,925,458...33,971,596
|
|
| G
|
Acer1
|
alkaline ceramidase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ACER1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 9:1,881,361...1,911,439
Ensembl chr 9:1,881,361...1,919,416
|
|
| G
|
Ache
|
acetylcholinesterase
|
decreases expression
|
EXP
|
Nickel results in decreased expression of ACHE mRNA
|
CTD |
PMID:18812211 |
|
NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410
|
|
| G
|
Acin1
|
apoptotic chromatin condensation inducer 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ACIN1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr15:32,072,121...32,117,004
Ensembl chr15:32,072,123...32,117,166
|
|
| G
|
Ackr4
|
atypical chemokine receptor 4
|
increases expression
|
ISO
|
Nickel results in increased expression of ACKR4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:113,595,325...113,599,762
Ensembl chr 8:113,595,293...113,602,372
|
|
| G
|
Aco1
|
aconitase 1
|
multiple interactions decreases expression increases activity
|
ISO
|
ferric sulfate inhibits the reaction [Nickel results in increased activity of ACO1 protein]; Iron inhibits the reaction [Nickel results in increased activity of ACO1 protein] Nickel results in decreased expression of ACO1 mRNA
|
CTD |
PMID:16386771 PMID:16877034 PMID:25583101 |
|
NCBI chr 5:60,055,895...60,111,920
Ensembl chr 5:60,055,866...60,112,600
|
|
| G
|
Acot4
|
acyl-CoA thioesterase 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ACOT4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 6:109,399,032...109,405,138
Ensembl chr 6:109,399,578...109,405,138
|
|
| G
|
Acot7
|
acyl-CoA thioesterase 7
|
increases expression
|
ISO
|
Nickel results in increased expression of ACOT7 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:167,969,284...168,062,033
Ensembl chr 5:167,968,895...168,062,033
|
|
| G
|
Acot9
|
acyl-CoA thioesterase 9
|
increases expression
|
ISO
|
Nickel results in increased expression of ACOT9 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr X:43,922,943...43,973,311
Ensembl chr X:43,914,923...43,973,205
|
|
| G
|
Acox1
|
acyl-CoA oxidase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ACOX1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr10:101,905,083...101,930,136
Ensembl chr10:101,905,083...101,930,136
|
|
| G
|
Acox2
|
acyl-CoA oxidase 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ACOX2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr15:19,090,820...19,122,392
Ensembl chr15:19,090,926...19,122,392
|
|
| G
|
Acp1
|
acid phosphatase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of ACP1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:53,233,937...53,249,576
Ensembl chr 6:53,233,948...53,251,959
|
|
| G
|
Acp6
|
acid phosphatase 6, lysophosphatidic
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ACP6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:187,400,786...187,421,877
Ensembl chr 2:187,349,186...187,422,743
|
|
| G
|
Acsbg1
|
acyl-CoA synthetase bubblegum family member 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ACSBG1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 8:63,887,433...63,943,486
Ensembl chr 8:63,887,435...63,984,178
|
|
| G
|
Acsf2
|
acyl-CoA synthetase family member 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ACSF2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:80,001,389...80,043,796
Ensembl chr10:80,001,389...80,045,050
|
|
| G
|
Acsl4
|
acyl-CoA synthetase long-chain family member 4
|
increases expression
|
ISO
|
Nickel results in increased expression of ACSL4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:110,739,633...110,803,416
Ensembl chr X:110,739,648...110,803,261
|
|
| G
|
Acsm3
|
acyl-CoA synthetase medium-chain family member 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ACSM3 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 1:183,564,652...183,591,328
Ensembl chr 1:183,564,635...183,591,437
|
|
| G
|
Acsm5
|
acyl-CoA synthetase medium-chain family member 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ACSM5 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:183,302,241...183,328,175
Ensembl chr 1:183,294,105...183,329,925
|
|
| G
|
Acss2
|
acyl-CoA synthetase short-chain family member 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ACSS2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:164,464,124...164,507,607
Ensembl chr 3:164,464,055...164,519,830
|
|
| G
|
Acss3
|
acyl-CoA synthetase short-chain family member 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ACSS3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:44,127,725...44,336,707
Ensembl chr 7:44,127,122...44,336,684
|
|
| G
|
Acta2
|
actin alpha 2, smooth muscle
|
multiple interactions decreases expression increases expression
|
ISO
|
[2-quinoxaline-carboxamide-N-adamantan-1-yl binds to and results in decreased activity of CASR protein] inhibits the reaction [Nickel results in increased expression of ACTA2 mRNA] [nickel chloride results in increased abundance of Nickel] which results in increased expression of ACTA2 mRNA; [nickel chloride results in increased abundance of Nickel] which results in increased expression of ACTA2 protein; Acetylcysteine inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of ACTA2 protein] Nickel results in decreased expression of ACTA2 mRNA
|
CTD |
PMID:19781536 PMID:24768652 PMID:25583101 PMID:38488660 |
|
NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503
|
|
| G
|
Actb
|
actin, beta
|
increases expression
|
ISO
|
Nickel results in increased expression of ACTB mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr12:16,776,664...16,779,634
Ensembl chr12:16,776,661...16,780,242
|
|
| G
|
Actg2
|
actin gamma 2, smooth muscle
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ACTG2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:117,579,513...117,604,379
Ensembl chr 4:117,579,514...117,604,295
|
|
| G
|
Actl6a
|
actin-like 6A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ACTL6A mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 2:117,413,206...117,436,758
Ensembl chr 2:117,418,601...117,436,754
|
|
| G
|
Actr2
|
actin related protein 2
|
increases expression
|
ISO
|
Nickel results in increased expression of ACTR2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:98,500,119...98,535,092
Ensembl chr14:98,500,138...98,541,998
|
|
| G
|
Acvr1c
|
activin A receptor type 1C
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ACVR1C mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:63,224,322...63,301,252
Ensembl chr 3:63,227,559...63,301,205
|
|
| G
|
Acvrl1
|
activin A receptor like type 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ACVRL1 mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr 7:134,117,917...134,135,306
Ensembl chr 7:134,118,024...134,135,305
|
|
| G
|
Acyp2
|
acylphosphatase 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ACYP2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr14:108,402,837...108,572,367
Ensembl chr14:108,402,544...108,633,318
|
|
| G
|
Adam10
|
ADAM metallopeptidase domain 10
|
increases expression
|
ISO
|
Nickel results in increased expression of ADAM10 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:80,226,862...80,358,728
Ensembl chr 8:80,226,674...80,361,600
|
|
| G
|
Adam12
|
ADAM metallopeptidase domain 12
|
increases expression
|
ISO
|
Nickel results in increased expression of ADAM12 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:198,116,968...198,443,680
Ensembl chr 1:198,116,975...198,447,552
|
|
| G
|
Adam19
|
ADAM metallopeptidase domain 19
|
increases expression
|
ISO
|
Nickel results in increased expression of ADAM19 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:30,992,713...31,084,455
Ensembl chr10:30,992,754...31,084,455
|
|
| G
|
Adam22
|
ADAM metallopeptidase domain 22
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ADAM22 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:26,670,984...26,925,843
Ensembl chr 4:26,671,112...26,925,843
|
|
| G
|
Adam33
|
ADAM metallopeptidase domain 33
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ADAM33 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:138,715,428...138,736,392
Ensembl chr 3:138,724,046...138,736,347
|
|
| G
|
Adam8
|
ADAM metallopeptidase domain 8
|
increases expression
|
ISO
|
Nickel results in increased expression of ADAM8 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:204,206,206...204,218,988
Ensembl chr 1:204,206,199...204,218,485
|
|
| G
|
Adamts1
|
ADAM metallopeptidase with thrombospondin type 1 motif, 1
|
increases expression
|
ISO
|
Nickel results in increased expression of ADAMTS1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr11:38,418,565...38,427,384
Ensembl chr11:38,418,101...38,427,390
|
|
| G
|
Adamts3
|
ADAM metallopeptidase with thrombospondin type 1, motif 3
|
increases expression
|
ISO
|
Nickel results in increased expression of ADAMTS3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr14:18,515,249...18,721,887
Ensembl chr14:18,515,249...18,721,887
|
|
| G
|
Adamts5
|
ADAM metallopeptidase with thrombospondin type 1 motif, 5
|
increases expression
|
ISO
|
Nickel results in increased expression of ADAMTS5 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:38,486,945...38,533,516
Ensembl chr11:38,486,955...38,533,516
|
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| G
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Adamts8
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ADAM metallopeptidase with thrombospondin type 1 motif, 8
|
increases expression
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ISO
|
Nickel results in increased expression of ADAMTS8 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:37,607,001...37,626,597
Ensembl chr 8:37,607,001...37,626,597
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| G
|
Adamts9
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ADAM metallopeptidase with thrombospondin type 1 motif, 9
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increases expression
|
ISO
|
Nickel results in increased expression of ADAMTS9 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:126,847,726...127,019,924
Ensembl chr 4:126,847,729...127,019,876
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| G
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Adamtsl1
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ADAMTS-like 1
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increases expression
|
ISO
|
Nickel results in increased expression of ADAMTSL1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:105,010,471...105,965,792
Ensembl chr 5:105,010,464...105,964,394
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| G
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Adamtsl4
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ADAMTS-like 4
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increases expression
|
ISO
|
Nickel results in increased expression of ADAMTSL4 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 2:185,924,582...185,936,039
Ensembl chr 2:185,924,594...185,935,796
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| G
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Adap2
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ArfGAP with dual PH domains 2
|
increases expression
|
ISO
|
Nickel results in increased expression of ADAP2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:65,635,891...65,665,019
Ensembl chr10:65,622,434...65,664,022
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| G
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Adcy2
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adenylate cyclase 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ADCY2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:36,204,054...36,650,645
Ensembl chr 1:36,204,054...36,650,645
|
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| G
|
Adcy6
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adenylate cyclase 6
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decreases expression
|
ISO
|
Nickel results in decreased expression of ADCY6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:131,621,860...131,642,923
Ensembl chr 7:131,621,860...131,642,770
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| G
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Adgra2
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adhesion G protein-coupled receptor A2
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decreases expression
|
ISO
|
Nickel results in decreased expression of ADGRA2 mRNA
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CTD |
PMID:25583101 |
|
NCBI chr16:71,635,814...71,674,275
Ensembl chr16:71,636,164...71,674,154
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| G
|
Adgrd1
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adhesion G protein-coupled receptor D1
|
increases expression
|
ISO
|
Nickel results in increased expression of ADGRD1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr12:33,124,981...33,239,778
Ensembl chr12:33,125,915...33,272,509
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| G
|
Adgre1
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adhesion G protein-coupled receptor E1
|
multiple interactions
|
ISO
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[Zinc co-treated with Nickel co-treated with Cobalt] affects the reaction [Dietary Fats affects the expression of ADGRE1 mRNA]
|
CTD |
PMID:23503329 |
|
NCBI chr 9:2,329,398...2,484,959
Ensembl chr 9:2,329,438...2,484,959
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| G
|
Adgre5
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adhesion G protein-coupled receptor E5
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decreases expression increases expression
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ISO
|
Nickel results in decreased expression of ADGRE5 mRNA Nickel results in increased expression of ADGRE5 mRNA
|
CTD |
PMID:12540486 PMID:24768652 PMID:25583101 |
|
NCBI chr19:41,302,687...41,332,183
Ensembl chr19:41,303,213...41,324,641
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| G
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Adgrf4
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adhesion G protein-coupled receptor F4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ADGRF4 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 9:25,769,265...25,800,438
Ensembl chr 9:25,769,265...25,800,438
|
|
| G
|
Adgrg1
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adhesion G protein-coupled receptor G1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ADGRG1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr19:10,009,983...10,047,138
Ensembl chr19:10,010,031...10,047,124
|
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| G
|
Adgrl3
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adhesion G protein-coupled receptor L3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ADGRL3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:26,690,891...27,458,132
Ensembl chr14:26,722,194...27,280,418
|
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| G
|
Adgrv1
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adhesion G protein-coupled receptor V1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ADGRV1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:13,067,149...13,647,407
Ensembl chr 2:13,067,150...13,647,372
|
|
| G
|
Adh1c
|
alcohol dehydrogenase 1C (class I), gamma polypeptide
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ADH1 mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr 2:229,470,703...229,482,291
Ensembl chr 2:229,470,703...229,482,291
|
|
| G
|
Adhfe1
|
alcohol dehydrogenase, iron containing, 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ADHFE1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:14,488,784...14,515,405
Ensembl chr 5:14,488,788...14,515,835
|
|
| G
|
Adk
|
adenosine kinase
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multiple interactions affects expression
|
ISO
|
trichostatin A inhibits the reaction [Nickel affects the expression of ADK mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr15:2,912,543...3,295,745
Ensembl chr15:2,912,544...3,295,745
|
|
| G
|
Adora1
|
adenosine A1 receptor
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ADORA1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:48,210,922...48,247,826
Ensembl chr13:48,213,273...48,247,190
|
|
| G
|
Adora2a
|
adenosine A2a receptor
|
increases expression
|
ISO
|
Nickel results in increased expression of ADORA2A mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr20:13,315,270...13,332,802
Ensembl chr20:13,315,270...13,332,802
|
|
| G
|
Adora2b
|
adenosine A2B receptor
|
increases expression
|
ISO
|
Nickel results in increased expression of ADORA2B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:47,439,712...47,456,092
Ensembl chr10:47,439,701...47,456,091
|
|
| G
|
Adpgk
|
ADP-dependent glucokinase
|
increases expression
|
ISO
|
Nickel results in increased expression of ADPGK mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:68,595,194...68,623,179
Ensembl chr 8:68,595,248...68,623,178
|
|
| G
|
Adra2a
|
adrenoceptor alpha 2A
|
increases expression
|
EXP
|
Nickel results in increased expression of ADRA2A mRNA
|
CTD |
PMID:18812211 |
|
NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:263,065,278...263,069,871
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|
| G
|
Adra2c
|
adrenoceptor alpha 2C
|
increases expression
|
EXP
|
Nickel results in increased expression of ADRA2C mRNA
|
CTD |
PMID:18812211 |
|
NCBI chr14:79,695,514...79,697,476
Ensembl chr14:79,694,995...79,706,656
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|
| G
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Adrb1
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adrenoceptor beta 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ADRB1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:265,777,103...265,780,114
Ensembl chr 1:265,766,079...265,849,237
|
|
| G
|
Adrb2
|
adrenoceptor beta 2
|
affects expression
|
EXP
|
Nickel affects the expression of ADRB2 mRNA
|
CTD |
PMID:18812211 |
|
NCBI chr18:57,912,760...57,914,802
Ensembl chr18:57,911,348...57,914,803
|
|
| G
|
Adss1
|
adenylosuccinate synthase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ADSS1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:137,500,549...137,523,087
Ensembl chr 6:137,501,001...137,523,086
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|
| G
|
Aen
|
apoptosis enhancing nuclease
|
increases expression
|
ISO
|
Nickel results in increased expression of AEN mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:142,224,499...142,233,902
Ensembl chr 1:142,224,493...142,233,898
|
|
| G
|
Afap1l1
|
actin filament associated protein 1-like 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of AFAP1L1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr18:57,454,120...57,514,584
Ensembl chr18:57,454,121...57,514,480
|
|
| G
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Afp
|
alpha-fetoprotein
|
decreases expression
|
ISO
|
Nickel analog results in decreased expression of AFP protein
|
CTD |
PMID:25144474 |
|
NCBI chr14:17,857,584...17,875,645
Ensembl chr14:17,857,584...17,875,649
|
|
| G
|
Agbl3
|
AGBL carboxypeptidase 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of AGBL3 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 4:64,416,139...64,498,987
Ensembl chr 4:64,421,397...64,498,985
|
|
| G
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Agfg2
|
ArfGAP with FG repeats 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of AGFG2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr12:24,649,008...24,692,069
Ensembl chr12:24,649,038...24,685,197
|
|
| G
|
Agl
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amylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of AGL mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 2:207,389,949...207,445,959
Ensembl chr 2:207,389,949...207,445,724
|
|
| G
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Ago2
|
argonaute RISC catalytic component 2
|
increases expression
|
ISO
|
Nickel results in increased expression of AGO2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:106,907,209...106,994,124
Ensembl chr 7:106,918,125...106,993,980
|
|
| G
|
Agpat3
|
1-acylglycerol-3-phosphate O-acyltransferase 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of AGPAT3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr20:10,330,650...10,415,026
Ensembl chr20:10,394,465...10,410,632
|
|
| G
|
Agpat5
|
1-acylglycerol-3-phosphate O-acyltransferase 5
|
increases expression
|
ISO
|
Nickel results in increased expression of AGPAT5 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr16:77,641,887...77,688,148
Ensembl chr16:77,641,887...77,688,148
|
|
| G
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Agps
|
alkylglycerone phosphate synthase
|
increases expression
|
ISO
|
Nickel results in increased expression of AGPS mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 3:81,154,599...81,253,099
Ensembl chr 3:81,154,604...81,258,277
|
|
| G
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Agt
|
angiotensinogen
|
affects binding
|
ISO
|
AGT protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944
|
|
| G
|
Agtr1a
|
angiotensin II receptor, type 1a
|
decreases expression
|
ISO
|
Nickel results in decreased expression of AGTR1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,381,467...34,435,660
|
|
| G
|
Ahcyl1
|
adenosylhomocysteinase-like 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of AHCYL1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 2:197,982,335...198,016,770
Ensembl chr 2:197,982,344...198,033,930
|
|
| G
|
Ahr
|
aryl hydrocarbon receptor
|
increases expression
|
ISO
|
Nickel results in increased expression of AHR mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
|
|
| G
|
Ahsg
|
alpha-2-HS-glycoprotein
|
affects binding
|
ISO
|
AHSG protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr11:91,625,975...91,632,583
Ensembl chr11:91,625,975...91,634,039
|
|
| G
|
Aif1
|
allograft inflammatory factor 1
|
increases expression
|
ISO
|
Nickel results in increased expression of AIF1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr20:3,651,435...3,657,341
Ensembl chr20:3,652,243...3,657,339
|
|
| G
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Aim2
|
absent in melanoma 2
|
decreases expression increases expression multiple interactions
|
ISO
|
Nickel results in decreased expression of AIM2 mRNA Nickel results in increased expression of AIM2 mRNA Melatonin affects the reaction [Nickel affects the reaction [SELENOM protein affects the expression of AIM2 mRNA]]; Melatonin inhibits the reaction [Nickel results in increased expression of AIM2 mRNA]; Nickel affects the reaction [Melatonin affects the reaction [SELENOM protein affects the expression of AIM2 mRNA]]; Nickel affects the reaction [SELENOM protein affects the expression of AIM2 mRNA]; Nickel inhibits the reaction [Melatonin results in decreased expression of AIM2 mRNA]
|
CTD |
PMID:23195993 PMID:25583101 PMID:36504304 |
|
NCBI chr13:88,397,516...88,439,325
Ensembl chr13:88,404,048...88,439,318
|
|
| G
|
Ak2
|
adenylate kinase 2
|
increases expression
|
ISO
|
Nickel results in increased expression of AK2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:146,609,469...146,649,008
Ensembl chr 5:146,630,445...146,650,610
|
|
| G
|
Ak9
|
adenylate kinase 9
|
decreases expression
|
ISO
|
Nickel results in decreased expression of AK9 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr20:46,307,100...46,523,537
Ensembl chr20:46,307,119...46,523,536
|
|
| G
|
Akap1
|
A-kinase anchoring protein 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of AKAP1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:74,118,232...74,151,366
Ensembl chr10:74,119,124...74,138,190
|
|
| G
|
Akap12
|
A-kinase anchoring protein 12
|
increases expression
|
ISO
|
Nickel results in increased expression of AKAP12 mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr 1:43,135,515...43,225,245
Ensembl chr 1:43,199,008...43,225,557
|
|
| G
|
Akirin2
|
akirin 2
|
increases expression
|
ISO
|
Nickel results in increased expression of AKIRIN2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:53,897,792...53,918,873
Ensembl chr 5:53,904,285...53,918,934
|
|
| G
|
Akna
|
AT-hook transcription factor
|
increases expression
|
ISO
|
Nickel results in increased expression of AKNA mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:81,792,928...81,839,936
Ensembl chr 5:81,792,929...81,831,528
|
|
| G
|
Akr1b10
|
aldo-keto reductase family 1 member B10
|
increases expression
|
ISO
|
Nickel results in increased expression of AKR1B10 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:64,005,632...64,027,860
Ensembl chr 4:64,007,420...64,020,847
|
|
| G
|
Akr1c3
|
aldo-keto reductase family 1, member C3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of AKR1C3 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr17:71,020,884...71,037,779
Ensembl chr17:70,970,900...71,048,438
|
|
| G
|
Akt1
|
AKT serine/threonine kinase 1
|
multiple interactions
|
ISO
|
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Melatonin inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in decreased expression of AKT1 mRNA]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Melatonin inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in decreased phosphorylation of AKT1 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [[nickel chloride results in increased abundance of Nickel] which results in decreased expression of AKT1 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [[nickel chloride results in increased abundance of Nickel] which results in decreased phosphorylation of AKT1 protein]; [nickel chloride results in increased abundance of Nickel] which results in decreased expression of AKT1 mRNA; [nickel chloride results in increased abundance of Nickel] which results in decreased phosphorylation of AKT1 protein; Melatonin inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in decreased expression of AKT1 mRNA]; Melatonin inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in decreased phosphorylation of AKT1 protein]; Nickel promotes the reaction [Particulate Matter results in decreased phosphorylation of AKT1 protein] [nickel chloride results in increased abundance of Nickel] which results in increased phosphorylation of AKT1 protein
|
CTD |
PMID:23788629 PMID:30724446 PMID:35568058 |
|
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
|
|
| G
|
Akt2
|
AKT serine/threonine kinase 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of AKT2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:92,004,705...92,061,420
Ensembl chr 1:92,014,859...92,061,420
|
|
| G
|
Aktip
|
AKT interacting protein
|
decreases expression
|
ISO
|
Nickel results in decreased expression of AKTIP mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr19:32,039,507...32,059,634
Ensembl chr19:32,039,466...32,067,178
|
|
| G
|
Alas1
|
5'-aminolevulinate synthase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ALAS1 mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr 8:115,755,238...115,768,642
Ensembl chr 8:115,755,238...115,768,642
|
|
| G
|
Alb
|
albumin
|
affects binding multiple interactions increases expression
|
ISO EXP
|
ALB protein binds to Nickel [Zinc co-treated with Copper co-treated with Manganese co-treated with Potassium Dichromate co-treated with Nickel co-treated with Cadmium co-treated with Lead co-treated with Mercury] affects the expression of ALB protein Nickel analog results in increased expression of ALB protein
|
CTD |
PMID:23896426 PMID:25144474 PMID:30090589 |
|
NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865
|
|
| G
|
Aldh1a1
|
aldehyde dehydrogenase 1 family, member A1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ALDH1A1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500
|
|
| G
|
Aldh1a2
|
aldehyde dehydrogenase 1 family, member A2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ALDH1A2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:80,758,641...80,837,891
Ensembl chr 8:80,758,142...80,837,883
|
|
| G
|
Aldh1l1
|
aldehyde dehydrogenase 1 family, member L1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ALDH1L1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:124,617,182...124,663,674
Ensembl chr 4:124,617,217...124,664,704
|
|
| G
|
Aldh3a1
|
aldehyde dehydrogenase 3 family, member A1
|
increases expression
|
ISO
|
Nickel results in increased expression of ALDH3A1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:46,392,464...46,402,151
Ensembl chr10:46,392,411...46,402,151
|
|
| G
|
Aldh5a1
|
aldehyde dehydrogenase 5 family, member A1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ALDH5A1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr17:40,560,373...40,586,711
Ensembl chr17:40,558,347...40,586,714
|
|
| G
|
Aldh6a1
|
aldehyde dehydrogenase 6 family, member A1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ALDH6A1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:109,809,092...109,829,725
Ensembl chr 6:109,809,122...109,829,743
|
|
| G
|
Aldoc
|
aldolase, fructose-bisphosphate C
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ALDOC mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:63,715,544...63,719,133
Ensembl chr10:63,715,489...63,719,133
|
|
| G
|
Alg10
|
ALG10, alpha-1,2-glucosyltransferase
|
increases expression
|
ISO
|
Nickel results in increased expression of ALG10 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:123,214,636...123,225,104
Ensembl chr 7:123,214,636...123,225,104
|
|
| G
|
Alg2
|
ALG2, alpha-1,3/1,6-mannosyltransferase
|
increases expression
|
ISO
|
Nickel results in increased expression of ALG2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:66,564,328...66,568,887
Ensembl chr 5:66,564,330...66,568,887
|
|
| G
|
Alkal2
|
ALK and LTK ligand 2
|
increases expression
|
ISO
|
Nickel results in increased expression of ALKAL2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:53,223,204...53,232,794
Ensembl chr 6:53,223,341...53,233,011
|
|
| G
|
Alkbh7
|
alkB homolog 7
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ALKBH7 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:1,925,896...1,928,048
Ensembl chr 9:1,925,743...1,928,048
|
|
| G
|
Alox12
|
arachidonate 12-lipoxygenase, 12S type
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ALOX12 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr10:55,456,923...55,469,239
Ensembl chr10:55,456,928...55,469,199
|
|
| G
|
Alox15
|
arachidonate 15-lipoxygenase
|
increases expression
|
ISO
|
Nickel results in increased expression of ALOX15 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:55,559,060...55,567,535
Ensembl chr10:55,559,061...55,567,723
|
|
| G
|
Alox15b
|
arachidonate 15-lipoxygenase, type B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ALOX15B mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr10:54,391,331...54,400,648
Ensembl chr10:54,391,302...54,400,648
|
|
| G
|
Alox5
|
arachidonate 5-lipoxygenase
|
increases expression
|
ISO
|
Nickel results in increased expression of ALOX5 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:151,203,948...151,251,126
Ensembl chr 4:151,203,949...151,251,126
|
|
| G
|
Alox5ap
|
arachidonate 5-lipoxygenase activating protein
|
increases expression
|
ISO
|
Nickel results in increased expression of ALOX5AP mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr12:10,785,254...10,809,295
Ensembl chr12:10,785,257...10,817,038
|
|
| G
|
Alyref
|
Aly/REF export factor
|
increases expression
|
ISO
|
Nickel results in increased expression of ALYREF mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:106,369,750...106,373,395
Ensembl chr10:106,369,750...106,373,395
|
|
| G
|
Ambp
|
alpha-1-microglobulin/bikunin precursor
|
affects binding
|
ISO
|
AMBP protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr 5:81,583,621...81,593,938
Ensembl chr 5:81,583,622...81,593,850
|
|
| G
|
Amd1
|
adenosylmethionine decarboxylase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of AMD1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr20:45,250,289...45,324,939
Ensembl chr20:45,250,289...45,265,982
|
|
| G
|
Amigo1
|
adhesion molecule with Ig like domain 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of AMIGO1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:198,511,285...198,516,744
Ensembl chr 2:198,511,039...198,521,146
|
|
| G
|
Amt
|
aminomethyltransferase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of AMT mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:117,859,700...117,866,692
Ensembl chr 8:117,860,345...117,866,803
|
|
| G
|
Ang
|
angiogenin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ANG mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr15:26,786,233...26,796,883
Ensembl chr15:26,786,065...26,801,106
|
|
| G
|
Angpt2
|
angiopoietin 2
|
increases expression
|
ISO
|
Nickel results in increased expression of ANGPT2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr16:77,790,760...77,841,241
Ensembl chr16:77,790,563...77,841,239
|
|
| G
|
Angptl1
|
angiopoietin-like 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ANGPTL1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:71,463,913...71,531,810
Ensembl chr13:71,511,727...71,531,818
|
|
| G
|
Angptl4
|
angiopoietin-like 4
|
increases expression multiple interactions
|
ISO
|
Nickel results in increased expression of ANGPTL4 mRNA [nickel chloride results in increased abundance of Nickel] which results in decreased methylation of ANGPTL4 promoter; [nickel chloride results in increased abundance of Nickel] which results in increased expression of ANGPTL4 mRNA; [nickel chloride results in increased abundance of Nickel] which results in increased expression of ANGPTL4 protein; TET1 protein affects the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of ANGPTL4 mRNA]; TET1 protein affects the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of ANGPTL4 protein]
|
CTD |
PMID:12540486 PMID:25583101 PMID:34571076 |
|
NCBI chr 7:15,252,450...15,259,971
Ensembl chr 7:15,252,473...15,258,681
|
|
| G
|
Angptl6
|
angiopoietin-like 6
|
increases expression
|
ISO
|
Nickel results in increased expression of ANGPTL6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:27,689,804...27,696,172
Ensembl chr 8:27,689,806...27,696,111
|
|
| G
|
Angptl7
|
angiopoietin like 7
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ANGPTL7 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:164,215,223...164,220,408
Ensembl chr 5:164,215,223...164,220,584
|
|
| G
|
Ank3
|
ankyrin 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ANK3 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr20:18,601,307...19,224,790
Ensembl chr20:18,601,826...19,084,879
|
|
| G
|
Ankdd1a
|
ankyrin repeat and death domain containing 1A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ANKDD1A mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:74,912,707...74,938,870
Ensembl chr 8:74,916,011...74,937,863
|
|
| G
|
Ankle2
|
ankyrin repeat and LEM domain containing 2
|
increases expression
|
ISO
|
Nickel results in increased expression of ANKLE2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr12:52,077,863...52,110,775
Ensembl chr12:52,077,480...52,108,708
|
|
| G
|
Ankrd13c
|
ankyrin repeat domain 13C
|
increases expression
|
ISO
|
Nickel results in increased expression of ANKRD13C mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:249,679,752...249,729,272
Ensembl chr 2:249,681,872...249,729,272
|
|
| G
|
Ankrd29
|
ankyrin repeat domain 29
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ANKRD29 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr18:3,711,052...3,768,997
Ensembl chr18:3,711,059...3,769,098
|
|
| G
|
Ankrd35
|
ankyrin repeat domain 35
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ANKRD35 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:186,895,896...186,915,903
Ensembl chr 2:186,895,945...186,915,902
|
|
| G
|
Ankrd44
|
ankyrin repeat domain 44
|
increases expression
|
ISO
|
Nickel results in increased expression of ANKRD44 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:63,621,193...63,921,999
Ensembl chr 9:63,555,869...63,921,940
|
|
| G
|
Ankrd50
|
ankyrin repeat domain containing 50
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ANKRD50 mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 2:123,394,311...123,428,788
Ensembl chr 2:123,396,606...123,427,340
|
|
| G
|
Anp32e
|
acidic nuclear phosphoprotein 32 family member E
|
increases expression
|
ISO
|
Nickel results in increased expression of ANP32E mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:186,161,520...186,177,984
Ensembl chr 2:186,161,532...186,177,986
|
|
| G
|
Anpep
|
alanyl aminopeptidase, membrane
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of ANPEP mRNA Nickel results in increased expression of ANPEP mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 1:143,176,645...143,219,447
Ensembl chr 1:143,176,645...143,195,101
|
|
| G
|
Antxr1
|
ANTXR cell adhesion molecule 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ANTXR1 mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr 4:121,148,102...121,335,549
Ensembl chr 4:121,148,103...121,336,892
|
|
| G
|
Anxa11
|
annexin A11
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ANXA11 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr16:1,419,627...1,464,590
Ensembl chr16:1,418,351...1,464,839
|
|
| G
|
Anxa2
|
annexin A2
|
increases expression
|
ISO
|
Nickel results in increased expression of ANXA2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:78,986,252...79,022,638
Ensembl chr 8:78,986,242...79,022,631
|
|
| G
|
Anxa4
|
annexin A4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ANXA4 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 4:120,741,750...120,798,534
Ensembl chr 4:120,741,750...120,798,513
|
|
| G
|
Anxa9
|
annexin A9
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ANXA9 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 2:185,562,174...185,572,560
Ensembl chr 2:185,562,174...185,572,560
|
|
| G
|
Aoah
|
acyloxyacyl hydrolase
|
increases expression
|
ISO
|
Nickel results in increased expression of AOAH mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr17:48,503,812...48,745,161
Ensembl chr17:48,503,812...48,745,146
|
|
| G
|
Aoc3
|
amine oxidase, copper containing 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of AOC3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:86,773,018...86,780,961
|
|
| G
|
Ap1s3
|
adaptor related protein complex 1 subunit sigma 3
|
increases expression
|
ISO
|
Nickel results in increased expression of AP1S3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:88,399,109...88,458,396
Ensembl chr 9:88,399,109...88,488,089
|
|
| G
|
Ap2a1
|
adaptor related protein complex 2 subunit alpha 1
|
multiple interactions
|
EXP
|
[Tungsten co-treated with Nickel co-treated with Cobalt] results in decreased expression of AP2A1 mRNA; [Tungsten co-treated with Nickel co-treated with Iron] results in decreased expression of AP2A1 mRNA
|
CTD |
PMID:24619124 |
|
NCBI chr 1:104,520,789...104,550,655
Ensembl chr 1:104,520,792...104,550,655
|
|
| G
|
Ap2b1
|
adaptor related protein complex 2 subunit beta 1
|
increases expression
|
ISO
|
Nickel results in increased expression of AP2B1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr10:68,596,925...68,702,547
Ensembl chr10:68,597,093...68,702,539
|
|
| G
|
Ap3m2
|
adaptor related protein complex 3 subunit mu 2
|
increases expression
|
ISO
|
Nickel results in increased expression of AP3M2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr16:75,908,459...75,937,915
Ensembl chr16:75,920,084...75,937,923
|
|
| G
|
Ap5s1
|
adaptor related protein complex 5 subunit sigma 1
|
increases expression
|
ISO
|
Nickel results in increased expression of AP5S1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:138,882,634...138,885,940
Ensembl chr 3:138,882,634...138,888,899
|
|
| G
|
Apaf1
|
apoptotic peptidase activating factor 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of APAF1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:27,381,855...27,466,772
|
|
| G
|
Apba1
|
amyloid beta precursor protein binding family A member 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of APBA1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:230,790,297...230,995,986
Ensembl chr 1:230,790,297...230,995,986
|
|
| G
|
Apbb1ip
|
amyloid beta precursor protein binding family B member 1 interacting protein
|
increases expression
|
ISO
|
Nickel results in increased expression of APBB1IP mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr17:89,849,474...89,941,099
Ensembl chr17:89,671,716...89,941,089
|
|
| G
|
Apcs
|
amyloid P component, serum
|
affects binding
|
ISO
|
APCS protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr13:87,905,532...87,906,508
Ensembl chr13:87,905,532...87,928,824
|
|
| G
|
Apex2
|
apurinic/apyrimidinic endodeoxyribonuclease 2
|
increases expression
|
ISO
|
Nickel results in increased expression of APEX2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr X:22,914,943...22,937,713
Ensembl chr X:22,914,944...22,936,011
|
|
| G
|
Apln
|
apelin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of APLN mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr X:132,058,739...132,091,518
Ensembl chr X:132,081,759...132,091,246
|
|
| G
|
Aplnr
|
apelin receptor
|
decreases expression
|
ISO
|
Nickel results in decreased expression of APLNR mRNA
|
CTD |
PMID:12540486 PMID:24768652 PMID:25583101 |
|
NCBI chr 3:90,624,055...90,627,700
Ensembl chr 3:90,624,012...90,627,908
|
|
| G
|
Apoa1
|
apolipoprotein A1
|
affects binding
|
ISO
|
APOA1 protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:55,423,825...55,425,729
|
|
| G
|
Apoa2
|
apolipoprotein A2
|
affects binding
|
ISO
|
APOA2 protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr13:86,176,767...86,178,819
Ensembl chr13:86,174,741...86,179,410
|
|
| G
|
Apoa4
|
apolipoprotein A4
|
affects binding decreases expression
|
ISO
|
APOA4 protein binds to Nickel Nickel analog results in decreased expression of APOA4 protein alternative form
|
CTD |
PMID:23896426 PMID:25144474 |
|
NCBI chr 8:55,435,779...55,438,160
Ensembl chr 8:55,434,168...55,438,164
|
|
| G
|
Apob
|
apolipoprotein B
|
affects binding
|
ISO
|
APOB protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr 6:36,563,704...36,603,300
Ensembl chr 6:36,563,704...36,611,814
|
|
| G
|
Apoc1
|
apolipoprotein C1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of APOC1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 1:88,475,018...88,479,052
Ensembl chr 1:88,474,663...88,478,155
|
|
| G
|
Apoc2
|
apolipoprotein C2
|
affects binding
|
ISO
|
APOC2 protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr 1:88,457,397...88,462,365
Ensembl chr 1:88,457,396...88,463,438
|
|
| G
|
Apoc3
|
apolipoprotein C3
|
affects binding
|
ISO
|
APOC3 protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr 8:55,428,172...55,430,352
Ensembl chr 8:55,428,024...55,458,679
|
|
| G
|
Apod
|
apolipoprotein D
|
affects binding
|
ISO
|
APOD protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr11:82,936,216...82,957,264
Ensembl chr11:82,936,038...82,957,263
|
|
| G
|
Apoe
|
apolipoprotein E
|
affects binding decreases expression
|
ISO
|
APOE protein binds to Nickel Nickel results in decreased expression of APOE mRNA
|
CTD |
PMID:23896426 PMID:24768652 PMID:25583101 |
|
NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855
|
|
| G
|
Apol2
|
apolipoprotein L2
|
increases expression
|
ISO
|
Nickel results in increased expression of APOL2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:111,211,944...111,219,209
Ensembl chr 7:111,211,893...111,217,223
|
|
| G
|
Apol9a
|
apolipoprotein L9a
|
increases expression
|
ISO
|
Nickel results in increased expression of APOL4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:111,021,452...111,030,380
Ensembl chr 7:111,021,453...111,028,213
|
|
| G
|
App
|
amyloid beta precursor protein
|
affects binding
|
ISO
|
Nickel binds to APP protein alternative form
|
CTD |
PMID:15699049 |
|
NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971
|
|
| G
|
Aqp3
|
aquaporin 3 (Gill blood group)
|
increases expression
|
ISO
|
Nickel results in increased expression of AQP3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:61,035,165...61,040,683
Ensembl chr 5:61,035,166...61,040,685
|
|
| G
|
Aqp5
|
aquaporin 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of AQP5 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:132,601,528...132,605,060
Ensembl chr 7:132,601,059...132,605,062
|
|
| G
|
Aqp7
|
aquaporin 7
|
decreases expression
|
ISO
|
Nickel results in decreased expression of AQP7 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:60,968,495...60,982,618
Ensembl chr 5:60,967,558...60,982,618
|
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| G
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Ar
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androgen receptor
|
decreases expression
|
ISO
|
Nickel results in decreased expression of AR mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467
|
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| G
|
Arap1
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ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ARAP1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 1:165,160,701...165,226,219
Ensembl chr 1:165,160,678...165,226,218
|
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| G
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Areg
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amphiregulin
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increases expression
|
ISO
|
Nickel results in increased expression of AREG mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:17,256,384...17,265,641
Ensembl chr14:17,256,384...17,265,641
|
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| G
|
Arf3
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ARF GTPase 3
|
increases expression
|
ISO
|
Nickel results in increased expression of ARF3 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 7:131,765,039...131,792,075
Ensembl chr 7:131,750,672...131,770,123
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| G
|
Arfgef1
|
ARF guanine nucleotide exchange factor 1
|
affects expression increases expression multiple interactions
|
ISO
|
Nickel affects the expression of ARFGEF1 mRNA Nickel results in increased expression of ARFGEF1 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of ARFGEF1 mRNA]
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CTD |
PMID:14575637 PMID:25583101 |
|
NCBI chr 5:13,764,507...13,859,237
Ensembl chr 5:13,764,975...13,859,237
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| G
|
Arfgef3
|
ARFGEF family member 3
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decreases expression
|
ISO
|
Nickel results in decreased expression of ARFGEF3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:15,058,574...15,223,742
Ensembl chr 1:15,058,579...15,223,742
|
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| G
|
Arfip1
|
ARF interacting protein 1
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decreases expression
|
ISO
|
Nickel results in decreased expression of ARFIP1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 2:172,141,862...172,224,464
Ensembl chr 2:172,141,859...172,221,280
|
|
| G
|
Arhgap1
|
Rho GTPase activating protein 1
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decreases expression
|
ISO
|
Nickel results in decreased expression of ARHGAP1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 3:98,077,064...98,099,163
Ensembl chr 3:98,077,150...98,099,154
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| G
|
Arhgap15
|
Rho GTPase activating protein 15
|
increases expression
|
ISO
|
Nickel results in increased expression of ARHGAP15 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:48,382,945...49,002,213
Ensembl chr 3:48,382,904...49,011,378
|
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| G
|
Arhgap24
|
Rho GTPase activating protein 24
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decreases expression
|
ISO
|
Nickel results in decreased expression of ARHGAP24 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr14:7,105,200...7,488,437
Ensembl chr14:7,105,200...7,528,950
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| G
|
Arhgap25
|
Rho GTPase activating protein 25
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decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of ARHGAP25 mRNA Nickel results in increased expression of ARHGAP25 mRNA
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CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 4:121,454,151...121,532,293
Ensembl chr 4:121,454,151...121,552,913
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| G
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Arhgap29
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Rho GTPase activating protein 29
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ARHGAP29 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:212,744,626...212,816,710
Ensembl chr 2:212,755,803...212,986,729
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| G
|
Arhgap30
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Rho GTPase activating protein 30
|
increases expression
|
ISO
|
Nickel results in increased expression of ARHGAP30 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:86,354,448...86,376,552
Ensembl chr13:86,354,547...86,376,888
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| G
|
Arhgap4
|
Rho GTPase activating protein 4
|
increases expression
|
ISO
|
Nickel results in increased expression of ARHGAP4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr X:156,787,566...156,802,841
Ensembl chr X:156,783,776...156,802,450
|
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| G
|
Arhgap44
|
Rho GTPase activating protein 44
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ARHGAP44 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:50,154,724...50,322,027
Ensembl chr10:50,154,724...50,321,897
|
|
| G
|
Arhgap45
|
Rho GTPase activating protein 45
|
increases expression
|
ISO
|
Nickel results in increased expression of ARHGAP45 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:10,325,515...10,340,955
Ensembl chr 7:10,325,539...10,341,890
|
|
| G
|
Arhgap9
|
Rho GTPase activating protein 9
|
increases expression
|
ISO
|
Nickel results in increased expression of ARHGAP9 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:65,034,023...65,042,336
Ensembl chr 7:65,034,144...65,042,336
|
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| G
|
Arhgdia
|
Rho GDP dissociation inhibitor alpha
|
increases expression
|
ISO
|
Nickel results in increased expression of ARHGDIA mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:106,352,858...106,356,347
Ensembl chr10:106,353,491...106,356,347
|
|
| G
|
Arhgdib
|
Rho GDP dissociation inhibitor beta
|
increases expression
|
ISO
|
Nickel results in increased expression of ARHGDIB mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:171,554,139...171,573,057
Ensembl chr 4:171,554,140...171,573,068
|
|
| G
|
Arhgef1
|
Rho guanine nucleotide exchange factor 1
|
increases expression
|
ISO
|
Nickel results in increased expression of ARHGEF1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:89,626,884...89,648,823
Ensembl chr 1:89,628,266...89,649,067
|
|
| G
|
Arhgef12
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Rho guanine nucleotide exchange factor 12
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ARHGEF12 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 8:52,247,047...52,373,158
Ensembl chr 8:52,247,047...52,372,376
|
|
| G
|
Arhgef2
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Rho/Rac guanine nucleotide exchange factor 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ARHGEF2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 2:176,358,909...176,416,178
Ensembl chr 2:176,358,904...176,417,646
|
|
| G
|
Arhgef28
|
Rho guanine nucleotide exchange factor 28
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ARHGEF28 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:30,998,292...31,294,757
Ensembl chr 2:30,998,295...31,294,853
|
|
| G
|
Arhgef3
|
Rho guanine nucleotide exchange factor 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ARHGEF3 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr16:2,308,311...2,588,634
Ensembl chr16:2,308,400...2,588,819
|
|
| G
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Arhgef9
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Cdc42 guanine nucleotide exchange factor 9
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of ARHGEF9 mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr X:63,929,168...64,087,267
Ensembl chr X:63,929,176...64,087,104
|
|
| G
|
Arid3b
|
AT-rich interaction domain 3B
|
increases expression
|
ISO
|
Nickel results in increased expression of ARID3B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:67,089,141...67,136,764
Ensembl chr 8:67,083,802...67,152,245
|
|
| G
|
Arid5a
|
AT-rich interaction domain 5A
|
increases expression
|
ISO
|
Nickel results in increased expression of ARID5A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:46,030,513...46,058,729
Ensembl chr 9:46,030,548...46,045,363
|
|
| G
|
Ark2c
|
arkadia (RNF111) C-terminal like ring finger ubiquitin ligase 2C
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ARK2C mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr18:73,259,736...73,375,987
Ensembl chr18:73,264,901...73,375,987
|
|
| G
|
Arl4a
|
ARF like GTPase 4A
|
increases expression
|
ISO
|
Nickel results in increased expression of ARL4A mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 6:62,809,287...62,811,297
Ensembl chr 6:62,804,548...62,820,760
|
|
| G
|
Arl4c
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ARF like GTPase 4C
|
increases expression
|
ISO
|
Nickel results in increased expression of ARL4C mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:96,748,075...96,751,510
Ensembl chr 9:96,745,069...96,752,772
|
|
| G
|
Arl4d
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ARF like GTPase 4D
|
increases expression
|
ISO
|
Nickel results in increased expression of ARL4D mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:87,092,276...87,103,079
Ensembl chr10:87,077,523...87,106,199
|
|
| G
|
Arl5b
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ARF like GTPase 5B
|
increases expression
|
ISO
|
Nickel results in increased expression of ARL5B mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr17:82,864,315...82,888,458
Ensembl chr17:82,864,287...82,890,646
|
|
| G
|
Armcx4
|
armadillo repeat containing, X-linked 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ARMCX4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:102,153,743...102,164,173
Ensembl chr X:102,153,800...102,164,633
|
|
| G
|
Armh1
|
armadillo-like helical domain containing 1
|
increases expression
|
ISO
|
Nickel results in increased expression of ARMH1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:135,919,057...135,958,653
Ensembl chr 5:135,919,057...135,958,626
|
|
| G
|
Armt1
|
acidic residue methyltransferase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DCPH1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 1:43,299,916...43,323,675
Ensembl chr 1:43,299,826...43,323,670
|
|
| G
|
Arpc1b
|
actin related protein 2/3 complex, subunit 1B
|
increases expression
|
ISO
|
Nickel results in increased expression of ARPC1B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr12:14,595,939...14,609,501
Ensembl chr12:14,595,678...14,609,504
|
|
| G
|
Arpc4
|
actin related protein 2/3 complex, subunit 4
|
increases expression
|
ISO
|
Nickel results in increased expression of ARPC4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:148,077,799...148,088,427
Ensembl chr 4:148,077,240...148,088,428
|
|
| G
|
Arpc5l
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actin related protein 2/3 complex, subunit 5-like
|
increases expression
|
ISO
|
Nickel results in increased expression of ARPC5L mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:43,169,518...43,177,224
Ensembl chr 3:43,169,462...43,177,240 Ensembl chr 9:43,169,462...43,177,240
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|
| G
|
Arrb2
|
arrestin, beta 2
|
increases expression
|
ISO
|
Nickel results in increased expression of ARRB2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,645,357...55,653,487
|
|
| G
|
Arsb
|
arylsulfatase B
|
increases expression
|
ISO
|
Nickel results in increased expression of ARSB mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:26,736,395...26,895,682
Ensembl chr 2:26,736,957...26,897,611
|
|
| G
|
Arv1
|
ARV1 homolog, fatty acid homeostasis modulator
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ARV1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr19:69,589,728...69,601,547
Ensembl chr19:69,589,328...69,601,537
|
|
| G
|
As3mt
|
arsenite methyltransferase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of AS3MT mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:255,536,879...255,569,245
Ensembl chr 1:255,537,109...255,569,249
|
|
| G
|
Asap1
|
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
|
increases expression
|
ISO
|
Nickel results in increased expression of ASAP1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:97,675,354...97,982,523
Ensembl chr 7:97,675,354...97,982,024
|
|
| G
|
Asb9
|
ankyrin repeat and SOCS box-containing 9
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ASB9 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:33,588,484...33,633,285
Ensembl chr X:33,588,484...33,624,397
|
|
| G
|
Ascc3
|
activating signal cointegrator 1 complex subunit 3
|
increases expression
|
ISO
|
Nickel results in increased expression of ASCC3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr20:55,089,430...55,372,374
Ensembl chr20:55,255,503...55,372,374
|
|
| G
|
Ascl2
|
achaete-scute family bHLH transcription factor 2
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of ASCL2 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of ASCL2 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 1:207,578,447...207,665,126
Ensembl chr 1:207,578,449...207,580,856
|
|
| G
|
Asf1b
|
anti-silencing function 1B histone chaperone
|
increases expression
|
ISO
|
Nickel results in increased expression of ASF1B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr19:41,085,786...41,100,352
Ensembl chr19:41,086,114...41,100,352
|
|
| G
|
Asgr2
|
asialoglycoprotein receptor 2
|
increases expression
|
ISO
|
Nickel results in increased expression of ASGR2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:55,320,082...55,333,294
Ensembl chr10:55,320,091...55,333,263
|
|
| G
|
Ash1l
|
ASH1 like histone lysine methyltransferase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ASH1L mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:176,644,393...176,780,848
Ensembl chr 2:176,644,924...176,780,847
|
|
| G
|
Asic5
|
acid sensing ion channel subunit family member 5
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of ASIC5 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of ASIC5 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 2:169,606,059...169,634,885
Ensembl chr 2:169,606,059...169,634,885
|
|
| G
|
Aspa
|
aspartoacylase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ASPA mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:58,390,204...58,443,790
Ensembl chr10:58,379,410...58,443,769
|
|
| G
|
Asphd2
|
aspartate beta-hydroxylase domain containing 2
|
increases expression
|
ISO
|
Nickel results in increased expression of ASPHD2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr12:49,908,539...49,919,060
Ensembl chr12:49,908,241...49,925,254
|
|
| G
|
Astn2
|
astrotactin 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ASTN2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:83,772,988...84,759,439
Ensembl chr 5:83,773,633...84,759,485
|
|
| G
|
Atad2
|
ATPase family, AAA domain containing 2
|
increases expression
|
ISO
|
Nickel results in increased expression of ATAD2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:91,523,626...91,566,238
Ensembl chr 7:91,523,626...91,566,238
|
|
| G
|
Atat1
|
alpha tubulin acetyltransferase 1
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of ATAT1 mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr20:2,849,399...2,862,614
Ensembl chr20:2,849,421...2,862,389
|
|
| G
|
Atf3
|
activating transcription factor 3
|
increases expression
|
ISO
|
Nickel results in increased expression of ATF3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:105,274,103...105,331,653
Ensembl chr13:105,282,440...105,295,750
|
|
| G
|
Atf5
|
activating transcription factor 5
|
increases expression
|
ISO
|
Nickel results in increased expression of ATF5 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:104,432,094...104,437,611
Ensembl chr 1:104,432,094...104,436,183
|
|
| G
|
Atf6
|
activating transcription factor 6
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of ATF6 mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr13:85,460,312...85,639,959
Ensembl chr13:85,462,840...85,640,033
|
|
| G
|
Atf7
|
activating transcription factor 7
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ATF7 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:135,537,351...135,649,188
Ensembl chr 7:135,542,111...135,599,899
|
|
| G
|
Atg12
|
autophagy related 12
|
multiple interactions
|
ISO
|
[Nickel co-treated with austenitic steel analog] results in increased expression of ATG12 mRNA
|
CTD |
PMID:23638002 |
|
NCBI chr18:41,638,841...41,649,311
Ensembl chr18:41,635,835...41,649,261
|
|
| G
|
Atg3
|
autophagy related 3
|
increases expression
|
ISO
|
Nickel results in increased expression of ATG3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr11:69,130,948...69,159,280
Ensembl chr11:69,121,952...69,159,280
|
|
| G
|
Atg5
|
autophagy related 5
|
multiple interactions increases expression
|
ISO
|
[Nickel co-treated with austenitic steel analog] results in increased expression of ATG5 mRNA 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Melatonin inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of ATG5 mRNA]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of ATG5 mRNA]; [nickel chloride results in increased abundance of Nickel] which results in increased expression of ATG5 mRNA; Melatonin inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of ATG5 mRNA] Nickel results in increased expression of ATG5 mRNA
|
CTD |
PMID:23638002 PMID:25583101 PMID:35568058 |
|
NCBI chr20:49,380,835...49,471,826
Ensembl chr20:49,380,813...49,471,821
|
|
| G
|
Atg7
|
autophagy related 7
|
decreases expression multiple interactions
|
ISO
|
Nickel results in decreased expression of ATG7 mRNA 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Melatonin inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of ATG7 mRNA]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Melatonin inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of ATG7 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of ATG7 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of ATG7 protein]; [nickel chloride results in increased abundance of Nickel] which results in increased expression of ATG7 mRNA; [nickel chloride results in increased abundance of Nickel] which results in increased expression of ATG7 protein; Melatonin inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of ATG7 mRNA]; Melatonin inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of ATG7 protein] [Nickel co-treated with austenitic steel analog] results in increased expression of ATG7 mRNA
|
CTD |
PMID:23195993 PMID:23638002 PMID:35568058 |
|
NCBI chr 4:149,390,000...149,597,534
Ensembl chr 4:149,391,390...149,598,319
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|
| G
|
Atg9b
|
autophagy related 9B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ATG9B mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 4:11,678,548...11,686,097
Ensembl chr 4:11,678,299...11,686,079
|
|
| G
|
Atl3
|
atlastin GTPase 3
|
increases expression
|
ISO
|
Nickel results in increased expression of ATL3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:214,110,127...214,151,098
Ensembl chr 1:214,109,702...214,152,510
|
|
| G
|
Atp13a1
|
ATPase 13A1
|
increases expression
|
ISO
|
Nickel results in increased expression of ATP13A1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr16:19,649,065...19,665,126
Ensembl chr16:19,649,066...19,665,120
|
|
| G
|
Atp13a2
|
ATPase cation transporting 13A2
|
increases response to substance decreases response to substance
|
ISO
|
ATP13A2 results in increased susceptibility to Nickel ATP13A2 protein results in decreased susceptibility to Nickel
|
CTD |
PMID:22768177 PMID:22847264 |
|
NCBI chr 5:158,575,727...158,595,157
Ensembl chr 5:158,575,749...158,595,156
|
|
| G
|
Atp13a3
|
ATPase 13A3
|
increases expression
|
ISO
|
Nickel results in increased expression of ATP13A3 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr11:83,860,725...83,946,899
Ensembl chr11:83,870,218...83,944,662
|
|
| G
|
Atp13a5
|
ATPase 13A5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ATP13A5 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:84,881,196...85,020,597
Ensembl chr11:84,881,230...85,020,593
|
|
| G
|
Atp1a2
|
ATPase Na+/K+ transporting subunit alpha 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ATP1A2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:87,261,964...87,286,911
Ensembl chr13:87,261,968...87,286,911
|
|
| G
|
Atp1b1
|
ATPase Na+/K+ transporting subunit beta 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ATP1B1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:79,319,708...79,340,226
Ensembl chr13:79,319,706...79,340,549
|
|
| G
|
Atp1b2
|
ATPase Na+/K+ transporting subunit beta 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ATP1B2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:54,817,473...54,823,708
Ensembl chr10:54,817,476...54,823,708
|
|
| G
|
Atp2a3
|
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
|
multiple interactions affects expression
|
ISO
|
trichostatin A inhibits the reaction [Nickel affects the expression of ATP2A3 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr10:58,079,710...58,111,279
Ensembl chr10:58,079,852...58,111,278
|
|
| G
|
Atp6ap1l
|
ATPase H+ transporting accessory protein 1 like
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ATP6AP1L mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:23,772,724...23,814,913
Ensembl chr 2:23,772,745...23,814,618
|
|
| G
|
Atp6v0a4
|
ATPase H+ transporting V0 subunit a4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ATP6V0A4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:67,727,145...67,809,092
Ensembl chr 4:67,727,145...67,809,092
|
|
| G
|
Atp6v1a
|
ATPase H+ transporting V1 subunit A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ATP6V1A mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr11:70,066,800...70,120,603
Ensembl chr11:70,035,134...70,120,603
|
|
| G
|
Atp6v1b1
|
ATPase H+ transporting V1 subunit B1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ATP6V1B1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:117,781,444...117,800,103
Ensembl chr 4:117,781,444...117,800,103
|
|
| G
|
Atp6v1b2
|
ATPase H+ transporting V1 subunit B2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ATP6V1B2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr16:25,384,254...25,408,388
Ensembl chr16:25,384,257...25,408,839
|
|
| G
|
Atp6v1c1
|
ATPase H+ transporting V1 subunit C1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ATP6V1C1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 7:71,719,326...71,757,191
Ensembl chr 7:71,719,404...71,757,184
|
|
| G
|
Atp6v1c2
|
ATPase H+ transporting V1 subunit C2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ATP6V1C2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 6:45,809,269...45,872,914
Ensembl chr 6:45,809,271...45,848,747
|
|
| G
|
Atp7b
|
ATPase copper transporting beta
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ATP7B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr16:76,654,725...76,726,092
Ensembl chr16:76,653,660...76,728,801
|
|
| G
|
Atp8b2
|
ATPase phospholipid transporting 8B2
|
increases expression
|
ISO
|
Nickel results in increased expression of ATP8B2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:177,676,205...177,699,575
Ensembl chr 2:177,676,208...177,699,575
|
|
| G
|
Aurka
|
aurora kinase A
|
increases expression
|
ISO
|
Nickel results in increased expression of AURKA mRNA
|
CTD |
PMID:19031421 |
|
NCBI chr 3:181,546,742...181,562,890
Ensembl chr 3:181,546,742...181,562,771
|
|
| G
|
Avil
|
advillin
|
increases expression
|
ISO
|
Nickel results in increased expression of AVIL mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:64,711,294...64,729,436
Ensembl chr 7:64,711,403...64,729,436
|
|
| G
|
Avl9
|
AVL9 cell migration associated
|
increases expression
|
ISO
|
Nickel results in increased expression of AVL9 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:87,291,062...87,338,537
Ensembl chr 4:87,291,798...87,331,916
|
|
| G
|
Awat1
|
acyl-CoA wax alcohol acyltransferase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of AWAT1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr X:69,708,286...69,714,531
Ensembl chr X:69,708,286...69,714,531
|
|
| G
|
Axdnd1
|
axonemal dynein light chain domain containing 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of AXDND1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr13:71,022,215...71,100,010
Ensembl chr13:71,021,404...71,094,233
|
|
| G
|
Axin2
|
axin 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of AXIN2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr10:94,393,379...94,426,579
Ensembl chr10:94,395,909...94,426,575
|
|
| G
|
Azgp1
|
alpha-2-glycoprotein 1, zinc-binding
|
decreases expression
|
ISO
|
Nickel results in decreased expression of AZGP1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr12:22,044,685...22,051,248
Ensembl chr12:22,044,751...22,053,020
|
|
| G
|
B2m
|
beta-2 microglobulin
|
increases expression
|
ISO
|
Nickel results in increased expression of B2M mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:129,549,236...129,555,354
Ensembl chr 3:129,549,318...129,555,356
|
|
| G
|
B3galt6
|
Beta-1,3-galactosyltransferase 6
|
increases expression
|
ISO
|
Nickel results in increased expression of B3GALT6 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:171,866,428...171,868,564
Ensembl chr 5:171,864,094...171,874,789
|
|
| G
|
Bak1
|
BCL2-antagonist/killer 1
|
increases expression
|
ISO
|
Nickel results in increased expression of BAK1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974
|
|
| G
|
Bambi
|
BMP and activin membrane-bound inhibitor
|
decreases expression
|
ISO
|
Nickel results in decreased expression of BAMBI mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr17:58,816,438...58,821,003
Ensembl chr17:58,816,442...58,821,247
|
|
| G
|
Batf
|
basic leucine zipper ATF-like transcription factor
|
increases expression
|
ISO
|
Nickel results in increased expression of BATF mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:111,084,717...111,107,052
Ensembl chr 6:111,084,717...111,107,052
|
|
| G
|
Batf2
|
basic leucine zipper ATF-like transcription factor 2
|
increases expression
|
ISO
|
Nickel results in increased expression of BATF2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:212,897,076...212,905,740
Ensembl chr 1:212,875,148...212,905,831
|
|
| G
|
Batf3
|
basic leucine zipper ATF-like transcription factor 3
|
increases expression
|
ISO
|
Nickel results in increased expression of BATF3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:105,220,782...105,232,365
Ensembl chr13:105,220,390...105,232,369
|
|
| G
|
Bax
|
BCL2 associated X, apoptosis regulator
|
multiple interactions increases expression affects expression
|
EXP ISO
|
Grape Seed Proanthocyanidins inhibits the reaction [Nickel results in increased expression of BAX protein] [cobalt ferrite binds to Nickel] which results in increased expression of BAX protein; [Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased expression of BAX protein; [nickel chloride results in increased abundance of Nickel] which results in increased expression of BAX protein; Luteolin affects the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased expression of BAX protein]; Nickel results in increased expression of and results in increased cleavage of BAX protein; Resveratrol inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of BAX protein] Nickel results in increased expression of BAX mRNA Nickel analog affects the expression of BAX protein Nickel analog results in increased expression of BAX protein; Nickel results in increased expression of BAX protein
|
CTD |
PMID:21417627 PMID:23776134 PMID:24768652 PMID:25583101 PMID:27257140 PMID:29115570 PMID:31943712 PMID:31953414 PMID:36073959 More...
|
|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
|
|
| G
|
Bbip1
|
BBSome interacting protein 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of BBIP1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:262,950,459...262,964,410
Ensembl chr 1:262,950,462...262,964,394
|
|
| G
|
Bcam
|
basal cell adhesion molecule (Lutheran blood group)
|
decreases expression
|
ISO
|
Nickel results in decreased expression of BCAM mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:88,542,971...88,557,358
Ensembl chr 1:88,542,972...88,557,888
|
|
| G
|
Bcat1
|
branched chain amino acid transaminase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of BCAT1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:179,695,662...179,777,973
Ensembl chr 4:179,695,662...179,777,288
|
|
| G
|
Bche
|
butyrylcholinesterase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of BCHE mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:160,607,289...160,699,760
Ensembl chr 2:160,606,288...160,699,760
|
|
| G
|
Bckdhb
|
branched chain keto acid dehydrogenase E1 subunit beta
|
decreases expression
|
ISO
|
Nickel results in decreased expression of BCKDHB mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:93,725,277...93,907,799
Ensembl chr 8:93,725,275...93,907,798
|
|
| G
|
Bcl11a
|
BCL11 transcription factor A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of BCL11A mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr14:102,230,147...102,325,289
Ensembl chr14:102,231,113...102,325,623
|
|
| G
|
Bcl2
|
BCL2, apoptosis regulator
|
multiple interactions decreases expression affects expression
|
ISO EXP
|
[cobalt ferrite binds to Nickel] which results in decreased expression of BCL2 protein; [Quercetin analog co-treated with Nickel] results in decreased expression of BCL2 protein Nickel results in decreased expression of BCL2 protein Nickel analog results in decreased expression of BCL2 protein Nickel analog affects the expression of BCL2 protein
|
CTD |
PMID:20577783 PMID:23776134 PMID:27257140 PMID:31953414 PMID:36073959 |
|
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
|
|
| G
|
Bcl2a1
|
BCL2-related protein A1
|
increases expression multiple interactions affects expression
|
ISO
|
Nickel results in increased expression of BCL2A1 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of BCL2A1A mRNA]
|
CTD |
PMID:14575637 PMID:24768652 PMID:25583101 |
|
NCBI chr 8:98,596,806...98,604,890
Ensembl chr 8:98,596,650...98,604,890
|
|
| G
|
Bcl2l11
|
Bcl2-like 11
|
multiple interactions affects expression
|
ISO
|
trichostatin A inhibits the reaction [Nickel affects the expression of BCL2L11 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 3:135,820,042...135,857,330
Ensembl chr 3:135,817,562...135,960,695
|
|
| G
|
Bcl2l14
|
Bcl2-like 14
|
increases expression
|
ISO
|
Nickel results in increased expression of BCL2L14 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 4:168,948,919...168,989,450
Ensembl chr 4:168,948,946...168,990,079
|
|
| G
|
Bcl3
|
BCL3, transcription coactivator
|
increases expression
|
ISO
|
Nickel results in increased expression of BCL3 mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 1:88,599,321...88,613,555
Ensembl chr 1:88,599,321...88,614,368
|
|
| G
|
Bcl6b
|
BCL6B, transcription repressor
|
decreases expression
|
ISO
|
Nickel results in decreased expression of BCL6B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:55,439,566...55,444,631
Ensembl chr10:55,432,382...55,444,631
|
|
| G
|
Bdh2
|
3-hydroxybutyrate dehydrogenase 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of BDH2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:226,376,346...226,397,010
Ensembl chr 2:226,376,356...226,397,006
|
|
| G
|
Bdkrb2
|
bradykinin receptor B2
|
increases expression
|
ISO
|
Nickel results in increased expression of BDKRB2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 6:130,237,055...130,267,205
Ensembl chr 6:130,237,255...130,267,209
|
|
| G
|
Bdnf
|
brain-derived neurotrophic factor
|
decreases expression
|
ISO
|
Nickel results in decreased expression of BDNF mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657
|
|
| G
|
Bean1
|
brain expressed, associated with NEDD4, 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of BEAN1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr19:745,993...792,853
Ensembl chr19:745,993...793,039
|
|
| G
|
Becn1
|
beclin 1
|
multiple interactions
|
ISO
|
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Melatonin inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of BECN1 mRNA]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Melatonin inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of BECN1 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of BECN1 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of BECN1 protein]; [nickel chloride results in increased abundance of Nickel] which results in increased expression of BECN1 mRNA; [nickel chloride results in increased abundance of Nickel] which results in increased expression of BECN1 protein; Melatonin inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of BECN1 mRNA]; Melatonin inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of BECN1 protein]
|
CTD |
PMID:35568058 |
|
NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002
|
|
| G
|
Bend2
|
BEN domain containing 2
|
increases expression
|
ISO
|
Nickel results in increased expression of BEND2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr X:36,997,518...37,093,363
Ensembl chr X:36,999,265...37,089,782
|
|
| G
|
Bend7
|
BEN domain containing 7
|
decreases expression
|
ISO
|
Nickel results in decreased expression of BEND7 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr17:78,392,489...78,475,459
Ensembl chr17:78,393,601...78,475,223
|
|
| G
|
Bex3
|
brain expressed X-linked 3
|
decreases expression
|
EXP
|
Nickel results in decreased expression of BEX3 mRNA
|
CTD |
PMID:19130878 |
|
NCBI chr X:104,064,896...104,066,425
Ensembl chr X:104,064,515...104,075,906
|
|
| G
|
Bex4
|
brain expressed, X-linked 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of BEX4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr X:103,923,609...103,925,041
Ensembl chr X:103,923,338...103,925,496
|
|
| G
|
Bhlhe22
|
basic helix-loop-helix family, member e22
|
decreases expression
|
ISO
|
Nickel results in decreased expression of BHLHE22 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 2:102,402,622...102,405,732
Ensembl chr 2:102,400,164...102,420,508
|
|
| G
|
Bhlhe41
|
basic helix-loop-helix family, member e41
|
decreases expression
|
ISO
|
Nickel results in decreased expression of BHLHE41 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 4:180,565,003...180,569,415
Ensembl chr 4:180,565,003...180,569,355
|
|
| G
|
Bicc1
|
BicC family RNA binding protein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of BICC1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr20:17,448,745...17,685,887
Ensembl chr20:17,448,765...17,685,885
|
|
| G
|
Bid
|
BH3 interacting domain death agonist
|
increases expression
|
ISO EXP
|
Nickel results in increased expression of BID mRNA Nickel analog results in increased expression of BID protein
|
CTD |
PMID:24768652 PMID:25583101 PMID:27257140 |
|
NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:155,785,377...155,808,275
|
|
| G
|
Bin2
|
bridging integrator 2
|
increases expression
|
ISO
|
Nickel results in increased expression of BIN2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:133,620,782...133,647,019
Ensembl chr 7:133,620,140...133,647,218
|
|
| G
|
Birc3
|
baculoviral IAP repeat-containing 3
|
increases expression
|
ISO
|
Nickel results in increased expression of BIRC3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:13,285,703...13,298,590
|
|
| G
|
Birc5
|
baculoviral IAP repeat-containing 5
|
multiple interactions increases expression
|
ISO
|
[Quercetin analog co-treated with Nickel] results in decreased expression of BIRC5 protein Nickel results in increased expression of BIRC5 mRNA
|
CTD |
PMID:19031421 PMID:20577783 PMID:25583101 |
|
NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155
|
|
| G
|
Blm
|
BLM RecQ like helicase
|
increases expression
|
ISO
|
Nickel results in increased expression of BLM mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:143,819,072...143,905,300
Ensembl chr 1:143,819,090...143,905,210
|
|
| G
|
Bmal2
|
basic helix-loop-helix ARNT like 2
|
increases expression
|
ISO
|
Nickel results in increased expression of BMAL2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:181,429,097...181,478,384
Ensembl chr 4:181,430,159...181,478,382
|
|
| G
|
Bmp1
|
bone morphogenetic protein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of BMP1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr15:51,961,310...52,005,597
Ensembl chr15:51,961,310...52,005,485
|
|
| G
|
Bmp2
|
bone morphogenetic protein 2
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of BMP2 mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:141,264,646...141,274,760
|
|
| G
|
Bmp2k
|
BMP-2 inducible kinase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of BMP2K mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr14:12,785,169...12,882,676
Ensembl chr14:12,785,169...12,882,657
|
|
| G
|
Bmp6
|
bone morphogenetic protein 6
|
increases expression
|
ISO
|
Nickel results in increased expression of BMP6 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr17:26,523,704...26,785,558
Ensembl chr17:26,523,704...26,675,261
|
|
| G
|
Bmp7
|
bone morphogenetic protein 7
|
decreases expression
|
ISO
|
Nickel results in decreased expression of BMP7 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 3:182,059,318...182,135,273
Ensembl chr 3:182,052,337...182,135,137
|
|
| G
|
Bnc1
|
basonuclin zinc finger protein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of BNC1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:145,326,881...145,352,534
Ensembl chr 1:145,326,892...145,353,510
|
|
| G
|
Bnc2
|
basonuclin zinc finger protein 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of BNC2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:103,724,934...104,061,890
Ensembl chr 5:103,724,934...104,125,428
|
|
| G
|
Bnip3
|
BCL2 interacting protein 3
|
multiple interactions
|
ISO
|
[nickel chloride results in increased abundance of Nickel] which results in increased expression of BNIP3 mRNA; [nickel chloride results in increased abundance of Nickel] which results in increased expression of BNIP3 protein
|
CTD |
PMID:36794572 |
|
NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:203,137,778...203,154,962
|
|
| G
|
Boc
|
BOC cell adhesion associated, oncogene regulated
|
decreases expression
|
ISO
|
Nickel results in decreased expression of BOC mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr11:69,628,703...69,704,009
Ensembl chr11:69,628,660...69,704,004
|
|
| G
|
Bop1
|
BOP1 ribosomal biogenesis factor
|
increases expression
|
ISO
|
Nickel results in increased expression of BOP1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:110,052,716...110,076,529
Ensembl chr 7:110,052,720...110,076,529
|
|
| G
|
Bphl
|
biphenyl hydrolase like
|
decreases expression
|
ISO
|
Nickel results in decreased expression of BPHL mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr17:31,006,283...31,042,631
Ensembl chr17:31,004,972...31,042,632
|
|
| G
|
Bpnt1
|
3'(2'), 5'-bisphosphate nucleotidase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of BPNT1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr13:99,397,127...99,425,056
Ensembl chr13:99,400,115...99,425,053
|
|
| G
|
Bpnt2
|
3'(2'), 5'-bisphosphate nucleotidase 2
|
increases expression
|
ISO
|
Nickel results in increased expression of BPNT2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:22,573,241...22,600,126
Ensembl chr 5:22,570,165...22,600,126
|
|
| G
|
Braf
|
B-Raf proto-oncogene, serine/threonine kinase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of BRAF mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:69,329,772...69,476,931
Ensembl chr 4:69,342,813...69,476,931
|
|
| G
|
Brd8
|
bromodomain containing 8
|
decreases expression
|
ISO
|
Nickel results in decreased expression of BRD8 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr18:26,455,824...26,504,106
Ensembl chr18:26,455,512...26,504,006
|
|
| G
|
Brip1
|
BRCA1 interacting DNA helicase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of BRIP1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:71,402,035...71,528,083
Ensembl chr10:71,401,151...71,575,206
|
|
| G
|
Brix1
|
biogenesis of ribosomes BRX1
|
multiple interactions affects expression
|
ISO
|
trichostatin A inhibits the reaction [Nickel affects the expression of BRIX1 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 2:61,177,769...61,188,647
Ensembl chr 2:61,177,771...61,188,647
|
|
| G
|
Bst2
|
bone marrow stromal cell antigen 2
|
increases expression
|
ISO
|
Nickel results in increased expression of BST2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr16:18,250,593...18,254,967
Ensembl chr16:18,251,847...18,254,967
|
|
| G
|
Btbd1
|
BTB domain containing 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of BTBD1 mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr 1:145,143,806...145,183,653
Ensembl chr 1:145,143,808...145,181,197
|
|
| G
|
Btbd19
|
BTB domain containing 19
|
increases expression
|
ISO
|
Nickel results in increased expression of BTBD19 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:135,834,251...135,843,679
Ensembl chr 5:135,834,508...135,840,903
|
|
| G
|
Btbd8
|
BTB domain containing 8
|
decreases expression
|
ISO
|
Nickel results in decreased expression of BTBD8 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr14:2,410,093...2,483,114
Ensembl chr14:2,410,093...2,479,202
|
|
| G
|
Btc
|
betacellulin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of BTC mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:16,992,668...17,031,178
Ensembl chr14:16,992,193...17,033,078
|
|
| G
|
Btd
|
biotinidase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of BTD mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr16:6,869,448...6,900,711
Ensembl chr16:6,869,291...6,901,410
|
|
| G
|
Btg2
|
BTG anti-proliferation factor 2
|
increases expression
|
ISO
|
Nickel results in increased expression of BTG2 mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr13:48,083,931...48,087,690
Ensembl chr13:48,083,931...48,087,690
|
|
| G
|
Btg3
|
BTG anti-proliferation factor 3
|
increases expression
|
ISO
|
Nickel results in increased expression of BTG3 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr11:30,517,068...30,532,981
Ensembl chr11:30,517,072...30,533,082
|
|
| G
|
Btk
|
Bruton tyrosine kinase
|
increases expression
|
ISO
|
Nickel results in increased expression of BTK mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr X:102,016,070...102,055,448
Ensembl chr X:102,016,074...102,055,143
|
|
| G
|
Btnl2
|
butyrophilin-like 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of BTNL2 mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr20:4,492,100...4,505,932
Ensembl chr20:4,492,111...4,505,932
|
|
| G
|
Btnl9
|
butyrophilin-like 9
|
decreases expression
|
ISO
|
Nickel results in decreased expression of BTNL9 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr10:33,967,098...33,990,304
Ensembl chr10:33,970,675...33,990,354
|
|
| G
|
Bub1
|
BUB1 mitotic checkpoint serine/threonine kinase
|
increases expression
|
ISO
|
Nickel results in increased expression of BUB1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:135,473,525...135,504,921
Ensembl chr 3:135,472,582...135,504,921
|
|
| G
|
Bub1b
|
BUB1 mitotic checkpoint serine/threonine kinase B
|
increases expression
|
ISO
|
Nickel results in increased expression of BUB1B mRNA
|
CTD |
PMID:19031421 PMID:25583101 |
|
NCBI chr 3:126,017,019...126,069,470
Ensembl chr 3:126,017,045...126,069,796
|
|
| G
|
Bysl
|
bystin-like
|
increases expression
|
ISO
|
Nickel results in increased expression of BYSL mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:20,880,341...20,890,092
Ensembl chr 9:20,880,026...20,890,900
|
|
| G
|
C10h16orf89
|
similar to human chromosome 16 open reading frame 89
|
decreases expression
|
ISO
|
Nickel results in decreased expression of C16ORF89 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:10,856,320...10,877,515
Ensembl chr10:10,868,419...10,877,515
|
|
| G
|
C10h17orf100
|
similar to human chromosome 17 open reading frame 100
|
decreases expression
|
ISO
|
Nickel results in decreased expression of C17ORF100 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr10:57,339,186...57,342,233
Ensembl chr10:57,337,035...57,341,474
|
|
| G
|
C10h17orf58
|
similar to human chromosome 17 open reading frame 58
|
increases expression
|
ISO
|
Nickel results in increased expression of C17ORF58 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:92,472,779...92,477,330
Ensembl chr10:92,471,934...92,477,330
|
|
| G
|
C10h5orf58
|
similar to human chromosome 5 open reading frame 58
|
increases expression
|
ISO
|
Nickel results in increased expression of C5ORF58 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:19,195,306...19,203,013
Ensembl chr10:19,193,035...19,205,380
|
|
| G
|
C11h3orf52
|
similar to human chromosome 3 open reading frame 52
|
decreases expression
|
ISO
|
Nickel results in decreased expression of C3ORF52 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr11:68,629,570...68,654,874
Ensembl chr11:68,629,570...68,654,868
|
|
| G
|
C11h3orf70
|
similar to human chromosome 3 open reading frame 70
|
decreases expression
|
ISO
|
Nickel results in decreased expression of C3ORF70 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr11:92,850,327...92,900,608
Ensembl chr11:92,850,327...92,900,608
|
|
| G
|
C13h1orf115
|
similar to human chromosome 1 open reading frame 115
|
decreases expression
|
ISO
|
Nickel results in decreased expression of C1ORF115 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:98,953,841...98,963,577
Ensembl chr13:98,953,843...98,963,810
|
|
| G
|
C15h14orf93
|
similar to human chromosome 14 open reading frame 93
|
decreases expression
|
ISO
|
Nickel results in decreased expression of C14ORF93 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr15:32,007,591...32,034,337
Ensembl chr15:32,007,595...32,034,289
|
|
| G
|
C16h8orf48
|
similar to human chromosome 8 open reading frame 48
|
increases expression
|
ISO
|
Nickel results in increased expression of C8ORF48 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr16:61,948,170...61,950,066
Ensembl chr16:61,879,158...61,971,067
|
|
| G
|
C18h5orf46
|
similar to human chromosome 5 open reading frame 46
|
decreases expression
|
ISO
|
Nickel results in decreased expression of C5ORF46 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr18:36,199,309...36,220,409
Ensembl chr18:36,199,309...36,220,409
|
|
| G
|
C1galt1
|
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
|
increases expression
|
ISO
|
Nickel results in increased expression of C1GALT1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:36,894,440...36,932,434
Ensembl chr 4:36,894,488...36,932,441
|
|
| G
|
C1h16orf54
|
similar to human chromosome 16 open reading frame 54
|
increases expression
|
ISO
|
Nickel results in increased expression of C16ORF54 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:191,132,972...191,135,653
Ensembl chr 1:191,132,030...191,135,910
|
|
| G
|
C1h19orf18
|
similar to human chromosome 19 open reading frame 18
|
decreases expression
|
ISO
|
Nickel results in decreased expression of C19ORF18 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:82,094,513...82,122,109
Ensembl chr 1:82,098,305...82,122,119
|
|
| G
|
C1h9orf85
|
similar to human chromosome 9 open reading frame 85
|
decreases expression
|
ISO
|
Nickel results in decreased expression of C9ORF85 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:228,562,621...228,624,472
Ensembl chr 1:228,564,731...228,624,278
|
|
| G
|
C1qb
|
complement C1q B chain
|
affects binding increases expression
|
ISO
|
C1QB protein binds to Nickel Nickel results in increased expression of C1QB mRNA
|
CTD |
PMID:23896426 PMID:24768652 PMID:25583101 |
|
NCBI chr 5:154,402,276...154,407,827
Ensembl chr 5:154,402,279...154,407,840
|
|
| G
|
C1qbp
|
complement C1q binding protein
|
increases expression
|
ISO
|
Nickel results in increased expression of C1QBP mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:56,198,534...56,203,185
Ensembl chr10:56,198,540...56,203,235
|
|
| G
|
C1qc
|
complement C1q C chain
|
increases expression
|
ISO
|
Nickel results in increased expression of C1QC mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:154,410,845...154,414,208
Ensembl chr 5:154,410,848...154,414,468
|
|
| G
|
C1qtnf1
|
C1q and TNF related 1
|
increases expression
|
ISO
|
Nickel results in increased expression of C1QTNF1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:104,159,021...104,180,253
Ensembl chr10:104,158,886...104,180,251
|
|
| G
|
C1qtnf3
|
C1q and TNF related 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of C1QTNF3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:61,644,225...61,666,640
Ensembl chr 2:61,644,276...61,666,559
|
|
| G
|
C1qtnf7
|
C1q and TNF related 7
|
decreases expression
|
ISO
|
Nickel results in decreased expression of C1QTNF7 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr14:71,680,415...71,792,931
Ensembl chr14:71,680,479...71,792,865
|
|
| G
|
C1r
|
complement C1r
|
affects binding increases expression
|
ISO
|
C1R protein binds to Nickel Nickel results in increased expression of C1R mRNA
|
CTD |
PMID:23896426 PMID:25583101 |
|
NCBI chr 4:159,099,013...159,109,770
Ensembl chr 4:159,098,918...159,109,714
|
|
| G
|
C1s
|
complement C1s
|
affects binding increases expression
|
ISO
|
C1S protein binds to Nickel Nickel results in increased expression of C1S mRNA
|
CTD |
PMID:23896426 PMID:25583101 |
|
NCBI chr 4:159,116,549...159,128,736
Ensembl chr 4:159,116,549...159,128,736
|
|
| G
|
C2
|
complement C2
|
increases expression
|
ISO
|
Nickel results in increased expression of C2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr20:3,944,722...3,975,006
Ensembl chr20:3,955,776...3,981,740
|
|
| G
|
C2cd4b
|
C2 calcium-dependent domain containing 4B
|
increases expression
|
ISO
|
Nickel results in increased expression of C2CD4B mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:77,254,327...77,277,620
Ensembl chr 8:77,238,551...77,279,879
|
|
| G
|
C2cd5
|
C2 calcium-dependent domain containing 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of C2CD5 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 4:177,700,515...177,790,576
Ensembl chr 4:177,700,516...177,786,717
|
|
| G
|
C2h1orf162
|
similar to human chromosome 1 open reading frame 162
|
increases expression
|
ISO
|
Nickel results in increased expression of C1ORF162 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:196,101,669...196,107,404
Ensembl chr 2:196,100,702...196,106,832
|
|
| G
|
C2h3orf80
|
similar to human chromosome 3 open reading frame 80
|
decreases expression
|
ISO
|
Nickel results in decreased expression of C3ORF80 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:155,435,287...155,438,099
Ensembl chr 2:155,434,073...155,437,507
|
|
| G
|
C2h4orf46
|
similar to human chromosome 4 open reading frame 46
|
increases expression
|
ISO
|
Nickel results in increased expression of C4ORF46 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:167,061,141...167,064,273
Ensembl chr 2:167,060,941...167,064,271
|
|
| G
|
C3
|
complement C3
|
affects binding increases expression
|
ISO
|
C3 protein binds to Nickel Nickel results in increased expression of C3 mRNA
|
CTD |
PMID:23896426 PMID:25583101 |
|
NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,174,412...2,201,339
|
|
| G
|
C3ar1
|
complement C3a receptor 1
|
increases expression
|
ISO
|
Nickel results in increased expression of C3AR1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:157,747,419...157,756,609
Ensembl chr 4:157,746,089...157,776,323
|
|
| G
|
C3h15orf48
|
similar to human chromosome 15 open reading frame 48
|
increases expression
|
ISO
|
Nickel results in increased expression of COXFA4L3 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 3:130,173,535...130,177,088
Ensembl chr 3:130,173,416...130,177,089
|
|
| G
|
C4b
|
complement C4B
|
affects binding
|
ISO
|
C4B protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr20:4,201,979...4,216,292
Ensembl chr20:4,201,961...4,216,289
|
|
| G
|
C4bpa
|
complement component 4 binding protein, alpha
|
affects binding
|
ISO
|
C4BPA protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr13:44,627,959...44,663,552
Ensembl chr13:44,627,982...44,663,471
|
|
| G
|
C4h2orf42
|
similar to human chromosome 2 open reading frame 42
|
decreases expression
|
ISO
|
Nickel results in decreased expression of C2ORF42 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 4:120,445,032...120,474,227
Ensembl chr 4:120,445,830...120,474,396
|
|
| G
|
C5
|
complement C5
|
decreases expression affects binding
|
ISO
|
Nickel results in decreased expression of HC mRNA C5 protein binds to Nickel
|
CTD |
PMID:12540486 PMID:23896426 |
|
NCBI chr 3:38,668,174...38,759,468
Ensembl chr 3:38,668,174...38,759,468
|
|
| G
|
C5ar1
|
complement C5a receptor 1
|
increases expression
|
ISO
|
Nickel results in increased expression of C5AR1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:86,077,309...86,088,001
|
|
| G
|
C5h1orf210
|
similar to human chromosome 1 open reading frame 210
|
decreases expression
|
ISO
|
Nickel results in decreased expression of C1ORF210 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 5:137,334,142...137,337,300
Ensembl chr 5:137,334,142...137,337,300
|
|
| G
|
C5h6orf163
|
similar to human chromosome 6 open reading frame 163
|
decreases expression
|
ISO
|
Nickel results in decreased expression of C6ORF163 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:54,113,073...54,132,787
Ensembl chr 5:54,112,859...54,126,074
|
|
| G
|
C5h8orf34
|
similar to human chromosome 8 open reading frame 34
|
decreases expression
|
ISO
|
Nickel results in decreased expression of C8ORF34 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:12,021,000...12,560,212
Ensembl chr 5:12,021,007...12,559,772
|
|
| G
|
C5h8orf88
|
similar to human chromosome 8 open reading frame 88
|
decreases expression
|
ISO
|
Nickel results in decreased expression of C8ORF88 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:33,127,385...33,152,914
Ensembl chr 5:33,126,632...33,174,768
|
|
| G
|
C5h9orf152
|
similar to human chromosome 9 open reading frame 152
|
decreases expression
|
ISO
|
Nickel results in decreased expression of C9ORF152 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:77,455,701...77,463,069
Ensembl chr 5:77,455,710...77,463,069
|
|
| G
|
C6
|
complement C6
|
affects binding
|
ISO
|
C6 protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr 2:55,573,596...55,648,857
Ensembl chr 2:55,573,653...55,649,120
|
|
| G
|
C6h14orf132
|
similar to human chromosome 14 open reading frame 132
|
decreases expression
|
ISO
|
Nickel results in decreased expression of C14ORF132 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 6:130,130,176...130,163,153
Ensembl chr 6:130,130,794...130,158,762
|
|
| G
|
C7
|
complement C7
|
affects binding decreases expression
|
ISO
|
C7 protein binds to Nickel Nickel results in decreased expression of C7 mRNA
|
CTD |
PMID:23896426 PMID:25583101 |
|
NCBI chr 2:55,815,687...55,892,605
Ensembl chr 2:55,816,807...55,892,672
|
|
| G
|
C7h8orf33
|
similar to human chromosome 8 open reading frame 33
|
increases expression
|
ISO
|
Nickel results in increased expression of C8ORF33 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:110,562,735...110,564,985
Ensembl chr 7:110,562,531...110,564,985
|
|
| G
|
C8a
|
complement C8 alpha chain
|
affects binding
|
ISO
|
C8A protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr 5:124,812,131...124,866,631
Ensembl chr 5:124,812,131...124,866,710
|
|
| G
|
C8b
|
complement C8 beta chain
|
affects binding
|
ISO
|
C8B protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr 5:124,763,974...124,801,522
Ensembl chr 5:124,761,790...124,801,516
|
|
| G
|
C8g
|
complement C8 gamma chain
|
affects binding
|
ISO
|
C8G protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr 3:28,718,648...28,720,232
|
|
| G
|
C8h11orf52
|
similar to human chromosome 11 open reading frame 52
|
decreases expression
|
ISO
|
Nickel results in decreased expression of C11ORF52 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:59,977,717...59,984,706
Ensembl chr 8:59,976,623...59,990,901
|
|
| G
|
C9
|
complement C9
|
affects binding
|
ISO
|
C9 protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr 2:57,300,510...57,348,759
Ensembl chr 2:57,300,427...57,348,752
|
|
| G
|
C9h2orf72
|
similar to human chromosome 2 open reading frame 72
|
decreases expression
|
ISO
|
Nickel results in decreased expression of C2ORF72 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:94,139,808...94,147,919
Ensembl chr 9:94,139,849...94,147,918
|
|
| G
|
C9h2orf88
|
similar to human chromosome 2 open reading frame 88
|
decreases expression
|
ISO
|
Nickel results in decreased expression of AKAP19 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:56,037,234...56,076,793
Ensembl chr 9:56,031,114...56,131,839
|
|
| G
|
C9h2orf92
|
similar to human chromosome 2 open reading frame 92
|
decreases expression
|
ISO
|
Nickel results in decreased expression of C2ORF92 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:46,439,554...46,480,735
Ensembl chr 9:46,440,408...46,480,733
|
|
| G
|
C9h6orf141
|
similar to human chromosome 6 open reading frame 141
|
decreases expression
|
ISO
|
Nickel results in decreased expression of C6ORF141 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:27,521,466...27,525,644
Ensembl chr 9:27,521,466...27,525,644
|
|
| G
|
Ca6
|
carbonic anhydrase 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CA6 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 5:165,941,028...165,959,566
Ensembl chr 5:165,941,029...165,959,566
|
|
| G
|
Cab39l
|
calcium binding protein 39-like
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CAB39L mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr15:37,782,778...37,885,191
Ensembl chr15:37,782,870...37,919,742
|
|
| G
|
Cables1
|
Cdk5 and Abl enzyme substrate 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CABLES1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr18:3,349,681...3,455,956
Ensembl chr18:3,351,652...3,455,956
|
|
| G
|
Cabyr
|
calcium binding tyrosine phosphorylation regulated
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CABYR mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr18:4,166,790...4,178,570
Ensembl chr18:4,166,858...4,179,507
|
|
| G
|
Cacna1d
|
calcium voltage-gated channel subunit alpha1 D
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CACNA1D mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr16:5,233,682...5,527,549
Ensembl chr16:5,233,690...5,674,692
|
|
| G
|
Cacna1e
|
calcium voltage-gated channel subunit alpha1 E
|
multiple interactions
|
ISO EXP
|
Nickel inhibits the reaction [CACNA1E protein results in increased transport of Calcium] Nickel inhibits the reaction [CACNA1E protein results in increased transport of Barium]
|
CTD |
PMID:10627594 PMID:10669483 |
|
NCBI chr13:69,125,048...69,613,795
Ensembl chr13:69,132,305...69,612,983
|
|
| G
|
Cacna1g
|
calcium voltage-gated channel subunit alpha1 G
|
multiple interactions
|
EXP
|
Nickel inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CACNA1G protein]
|
CTD |
PMID:17110049 |
|
NCBI chr10:79,851,886...79,919,926
Ensembl chr10:79,851,896...79,919,634
|
|
| G
|
Cacna1h
|
calcium voltage-gated channel subunit alpha1 H
|
multiple interactions
|
ISO EXP
|
Nickel inhibits the reaction [CACNA1H protein results in increased transport of Calcium] Nickel inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CACNA1H protein]
|
CTD |
PMID:9930755 PMID:11897840 PMID:17110049 |
|
NCBI chr10:14,894,630...14,952,317
Ensembl chr10:14,894,641...14,952,771
|
|
| G
|
Cacna1i
|
calcium voltage-gated channel subunit alpha1 I
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of CACNA1I mRNA; Nickel inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CACNA1I protein]
|
CTD |
PMID:17110049 PMID:31734292 |
|
NCBI chr 7:113,716,266...113,827,670
Ensembl chr 7:113,716,266...113,827,670
|
|
| G
|
Cacnb2
|
calcium voltage-gated channel auxiliary subunit beta 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CACNB2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr17:82,473,097...82,818,564
Ensembl chr17:82,473,129...82,818,564
|
|
| G
|
Cadm1
|
cell adhesion molecule 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CADM1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:56,744,374...57,075,264
Ensembl chr 8:56,744,372...57,080,192
|
|
| G
|
Cadm2
|
cell adhesion molecule 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CADM2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:17,994,856...18,971,895
Ensembl chr11:17,994,856...18,971,448
|
|
| G
|
Calb2
|
calbindin 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CALB2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr19:55,023,849...55,050,858
Ensembl chr19:55,023,838...55,057,952
|
|
| G
|
Calhm2
|
calcium homeostasis modulator family member 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CALHM2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 1:255,963,661...255,969,387
Ensembl chr 1:255,963,663...255,969,387
|
|
| G
|
Calhm6
|
calcium homeostasis modulator family member 6
|
increases expression
|
ISO
|
Nickel results in increased expression of CALHM6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr20:26,638,721...26,640,466
Ensembl chr20:26,638,722...26,640,408
|
|
| G
|
Calm3
|
calmodulin 3
|
increases expression
|
ISO
|
Nickel results in increased expression of CALM3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:86,718,761...86,725,869
Ensembl chr 1:86,717,321...86,725,960
|
|
| G
|
Calr
|
calreticulin
|
increases expression
|
ISO
|
Nickel results in increased expression of CALR mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr19:40,213,367...40,218,262
Ensembl chr19:40,213,239...40,219,236
|
|
| G
|
Calr3
|
calreticulin 3
|
multiple interactions
|
ISO
|
MT1 affects the reaction [Nickel affects the expression of CALR3 mRNA]; MT2 affects the reaction [Nickel affects the expression of CALR3 mRNA]
|
CTD |
PMID:16166738 |
|
NCBI chr16:17,430,105...17,456,777
Ensembl chr16:17,430,153...17,457,198
|
|
| G
|
Calu
|
calumenin
|
increases expression
|
ISO
|
Nickel results in increased expression of CALU mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:58,914,456...58,941,957
Ensembl chr 4:58,914,421...58,941,956
|
|
| G
|
Camk2n1
|
calcium/calmodulin-dependent protein kinase II inhibitor 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CAMK2N1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:155,958,116...155,959,897
Ensembl chr 5:155,957,878...155,961,058
|
|
| G
|
Camk4
|
calcium/calmodulin-dependent protein kinase IV
|
increases expression
|
ISO
|
Nickel results in increased expression of CAMK4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr18:24,857,152...25,076,054
Ensembl chr18:24,857,146...25,077,193
|
|
| G
|
Camsap3
|
calmodulin regulated spectrin-associated protein family, member 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CAMSAP3 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr12:6,440,959...6,464,582
Ensembl chr12:6,441,152...6,464,582
|
|
| G
|
Canx
|
calnexin
|
multiple interactions
|
ISO
|
MT1 affects the reaction [Nickel affects the expression of CANX mRNA]; MT2 affects the reaction [Nickel affects the expression of CANX mRNA]
|
CTD |
PMID:16166738 |
|
NCBI chr10:35,124,941...35,157,954
Ensembl chr10:35,124,941...35,157,857
|
|
| G
|
Cap2
|
cyclase associated actin cytoskeleton regulatory protein 2
|
increases expression decreases expression
|
ISO
|
Nickel results in increased expression of CAP2 mRNA Nickel results in decreased expression of CAP2 mRNA
|
CTD |
PMID:18922574 PMID:24768652 PMID:25583101 |
|
NCBI chr17:18,260,462...18,409,681
Ensembl chr17:18,261,646...18,409,563
|
|
| G
|
Capn13
|
calpain 13
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CAPN13 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:27,823,664...27,918,676
Ensembl chr 6:27,823,517...27,918,665
|
|
| G
|
Capn15
|
calpain 15
|
increases expression
|
ISO
|
Nickel results in increased expression of CAPN15 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:15,477,311...15,503,913
Ensembl chr10:15,477,313...15,503,913
|
|
| G
|
Capn2
|
calpain 2
|
increases expression
|
ISO
|
Nickel results in increased expression of CAPN2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr13:96,681,902...96,732,625
Ensembl chr13:96,681,848...96,732,625
|
|
| G
|
Capn5
|
calpain 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CAPN5 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:161,827,474...161,884,142
Ensembl chr 1:161,827,474...161,884,142
|
|
| G
|
Capn6
|
calpain 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CAPN6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:112,177,467...112,202,178
Ensembl chr X:112,177,467...112,202,178
|
|
| G
|
Capn8
|
calpain 8
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CAPN8 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr13:96,783,640...96,847,825
Ensembl chr13:96,783,667...96,847,820
|
|
| G
|
Caprin1
|
cell cycle associated protein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of CAPRIN1 mRNA
|
CTD |
PMID:18922574 |
|
NCBI chr 3:110,606,489...110,685,408
Ensembl chr 3:110,606,489...110,685,562
|
|
| G
|
Capza3
|
capping actin protein of muscle Z-line subunit alpha 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CAPZA3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:174,660,446...174,661,659
Ensembl chr 4:174,659,693...174,665,846
|
|
| G
|
Car2
|
carbonic anhydrase 2
|
increases expression
|
ISO
|
Nickel results in increased expression of CA2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064
|
|
| G
|
Card6
|
caspase recruitment domain family, member 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CARD6 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 2:55,921,832...55,934,388
Ensembl chr 2:55,921,832...55,934,363
|
|
| G
|
Carhsp1
|
calcium regulated heat stable protein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of CARHSP1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:7,453,602...7,467,218
Ensembl chr10:7,452,978...7,467,770
|
|
| G
|
Carmn
|
cardiac mesoderm enhancer-associated non-coding RNA
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CARMN mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr18:57,368,191...57,389,112
Ensembl chr18:57,360,134...57,389,921
|
|
| G
|
Casp1
|
caspase 1
|
multiple interactions increases expression decreases expression
|
EXP ISO
|
[Nickel co-treated with Cobalt co-treated with Tungsten] results in decreased expression of CASP1 mRNA [SELENOM protein affects the susceptibility to Nickel] which affects the expression of CASP1 mRNA; [SELENOM protein affects the susceptibility to Nickel] which affects the expression of CASP1 protein; Melatonin affects the reaction [[SELENOM protein affects the susceptibility to Nickel] which affects the expression of CASP1 mRNA]; Melatonin affects the reaction [[SELENOM protein affects the susceptibility to Nickel] which affects the expression of CASP1 protein]; Melatonin inhibits the reaction [Nickel results in increased expression of CASP1 mRNA] Nickel results in increased expression of CASP1 mRNA; Nickel results in increased expression of CASP1 protein [nickel chloride results in increased abundance of Nickel] which results in increased cleavage of CASP1 protein; Resveratrol inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased cleavage of CASP1 protein] Nickel results in decreased expression of CASP1 mRNA
|
CTD |
PMID:22198552 PMID:23195993 PMID:24768652 PMID:25583101 PMID:31943712 PMID:36504304 More...
|
|
NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275
|
|
| G
|
Casp3
|
caspase 3
|
multiple interactions increases expression increases cleavage increases activity
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ISO EXP
|
[cobalt ferrite binds to Nickel] which results in increased expression of CASP3 protein modified form; [Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased cleavage of CASP3 protein; [nickel chloride results in increased abundance of Nickel] which results in increased cleavage of CASP3 protein; [Nickel co-treated with austenitic steel analog] results in increased expression of CASP3 mRNA; [Quercetin analog co-treated with Nickel] results in increased activity of CASP3 protein; Luteolin inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased cleavage of CASP3 protein]; Nickel results in increased cleavage of and results in increased activity of CASP3 protein; Resveratrol inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased cleavage of CASP3 protein]; TP53 protein affects the reaction [Nickel results in increased cleavage of and results in increased activity of CASP3 protein] Nickel analog results in increased expression of CASP3 mRNA Nickel results in increased cleavage of CASP3 protein Nickel analog results in increased activity of CASP3 protein; Nickel results in increased activity of CASP3 protein [Tungsten co-treated with Nickel co-treated with Cobalt] results in decreased activity of CASP3 protein
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CTD |
PMID:20577783 PMID:20934443 PMID:21376802 PMID:23638002 PMID:23776134 PMID:24068677 PMID:24840272 PMID:27257140 PMID:29115570 PMID:31943712 PMID:31953414 PMID:36073959 More...
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|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
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|
| G
|
Casp4
|
caspase 4
|
increases expression
|
ISO
|
Nickel results in increased expression of CASP4 mRNA
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CTD |
PMID:25583101 |
|
NCBI chr 8:10,883,817...10,919,978
Ensembl chr 8:10,883,769...10,920,727
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|
| G
|
Casp7
|
caspase 7
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multiple interactions
|
ISO
|
Nickel results in increased cleavage of and results in increased activity of CASP7 protein
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CTD |
PMID:24068677 |
|
NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512
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|
| G
|
Casp8
|
caspase 8
|
increases expression increases cleavage multiple interactions
|
ISO EXP
|
Nickel results in increased expression of CASP8 mRNA Nickel analog results in increased expression of CASP8 mRNA Nickel results in increased cleavage of CASP8 protein [cobalt ferrite binds to Nickel] which results in increased expression of CASP8 protein modified form; [Nickel co-treated with austenitic steel analog] results in increased expression of CASP8 mRNA; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Nickel results in increased cleavage of CASP8 protein]
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CTD |
PMID:21054559 PMID:23638002 PMID:24840272 PMID:27257140 PMID:36073959 |
|
NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
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|
| G
|
Casp9
|
caspase 9
|
multiple interactions increases cleavage increases expression
|
ISO EXP
|
[cobalt ferrite binds to Nickel] which results in increased expression of CASP9 protein modified form; [Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased cleavage of CASP9 protein; [Nickel co-treated with austenitic steel analog] results in increased expression of CASP9 mRNA; [Quercetin analog co-treated with Nickel] results in increased activity of CASP9 protein; Luteolin inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased cleavage of CASP9 protein] Nickel results in increased cleavage of CASP9 protein Nickel analog results in increased expression of CASP9 mRNA
|
CTD |
PMID:20577783 PMID:23638002 PMID:27257140 PMID:29115570 PMID:31953414 PMID:36073959 More...
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|
Ensembl chr 5:159,391,188...159,409,648
|
|
| G
|
Casq2
|
calsequestrin 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CASQ2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:192,214,556...192,270,821
Ensembl chr 2:192,214,537...192,270,820
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|
| G
|
Casr
|
calcium-sensing receptor
|
multiple interactions increases activity
|
ISO
|
[2-quinoxaline-carboxamide-N-adamantan-1-yl binds to and results in decreased activity of CASR protein] inhibits the reaction [Nickel results in increased abundance of Calcium]; [2-quinoxaline-carboxamide-N-adamantan-1-yl binds to and results in decreased activity of CASR protein] inhibits the reaction [Nickel results in increased expression of ACTA2 mRNA]; [2-quinoxaline-carboxamide-N-adamantan-1-yl binds to and results in decreased activity of CASR protein] inhibits the reaction [Nickel results in increased expression of COL1A1 mRNA]; [2-quinoxaline-carboxamide-N-adamantan-1-yl binds to and results in decreased activity of CASR protein] inhibits the reaction [Nickel results in increased expression of ICAM1 mRNA]; [2-quinoxaline-carboxamide-N-adamantan-1-yl binds to and results in decreased activity of CASR protein] inhibits the reaction [Nickel results in increased expression of IL1B mRNA]; [2-quinoxaline-carboxamide-N-adamantan-1-yl binds to and results in decreased activity of CASR protein] inhibits the reaction [Nickel results in increased expression of TNF mRNA]; [2-quinoxaline-carboxamide-N-adamantan-1-yl binds to and results in decreased activity of CASR protein] which results in decreased susceptibility to Nickel; CASR protein affects the reaction [Nickel results in increased abundance of Calcium] Nickel results in increased activity of CASR protein
|
CTD |
PMID:19781536 |
|
NCBI chr11:77,738,398...77,813,639
Ensembl chr11:77,740,614...77,810,167
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|
| G
|
Cat
|
catalase
|
multiple interactions decreases activity increases activity
|
ISO EXP
|
[cobalt ferrite binds to Nickel] which results in decreased expression of CAT protein; CAT protein affects the reaction [Nickel results in increased expression of PTGS2] [nickel chloride results in increased abundance of Nickel] which results in decreased activity of CAT protein; Acetylcysteine inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in decreased activity of CAT protein] Nickel analog results in decreased activity of CAT protein [[nickel chloride results in increased abundance of Nickel] co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] results in decreased activity of CAT protein; [Arsenic co-treated with Cadmium co-treated with Lead co-treated with Mercury co-treated with Chromium co-treated with Nickel co-treated with Manganese co-treated with Iron] results in decreased activity of CAT protein; [nickel chloride results in increased abundance of Nickel] which results in decreased activity of CAT protein; caffeic acid inhibits the reaction [Nickel results in decreased activity of CAT protein]; Fatty Acids, Omega-3 inhibits the reaction [[[nickel chloride results in increased abundance of Nickel] co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] results in decreased activity of CAT protein] Nickel analog results in decreased activity of CAT protein; Nickel results in decreased activity of CAT protein Nickel results in increased activity of CAT protein
|
CTD |
PMID:17176674 PMID:18405891 PMID:20021064 PMID:21417627 PMID:21486220 PMID:25169089 PMID:27257140 PMID:31639282 PMID:36073959 PMID:38488660 More...
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|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
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|
| G
|
Cavin2
|
caveolae associated protein 2
|
increases expression decreases expression
|
ISO
|
Nickel results in increased expression of CAVIN2 mRNA Nickel results in decreased expression of CAVIN2 mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr 9:57,794,007...57,806,024
Ensembl chr 9:57,794,019...57,806,024
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|
| G
|
Cblb
|
Cbl proto-oncogene B
|
increases expression
|
ISO
|
Nickel results in increased expression of CBLB mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr11:62,058,829...62,225,904
Ensembl chr11:62,061,653...62,225,778
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|
| G
|
Cbln2
|
cerebellin 2 precursor
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CBLN2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr18:82,215,210...82,222,648
Ensembl chr18:82,215,220...82,222,648
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|
| G
|
Cbx2
|
chromobox 2
|
increases expression
|
ISO
|
Nickel results in increased expression of CBX2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:104,777,054...104,785,922
Ensembl chr10:104,777,056...104,785,926
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|
| G
|
Cbx7
|
chromobox 7
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CBX7 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:113,341,030...113,358,716
Ensembl chr 7:113,341,030...113,358,346
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|
| G
|
Cc2d2a
|
coiled-coil and C2 domain containing 2A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CC2D2A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:71,563,835...71,648,352
Ensembl chr14:71,563,835...71,648,331
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|
| G
|
Ccdc121
|
coiled-coil domain containing 121
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CCDC121 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:30,690,831...30,693,437
Ensembl chr 6:30,690,831...30,693,437
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|
| G
|
Ccdc137
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coiled-coil domain containing 137
|
increases expression
|
ISO
|
Nickel results in increased expression of CCDC137 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:106,229,099...106,235,502
Ensembl chr10:106,229,099...106,235,502
|
|
| G
|
Ccdc146
|
coiled-coil domain containing 146
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CCDC146 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:14,554,966...14,703,801
Ensembl chr 4:14,554,966...14,703,799
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|
| G
|
Ccdc149
|
coiled-coil domain containing 149
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CCDC149 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:62,722,567...62,817,778
Ensembl chr14:62,722,600...62,817,777
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|
| G
|
Ccdc160
|
coiled-coil domain containing 160
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CCDC160 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr X:137,389,066...137,399,452
Ensembl chr X:137,389,032...137,400,325
|
|
| G
|
Ccdc167
|
coiled-coil domain containing 167
|
increases expression
|
ISO
|
Nickel results in increased expression of CCDC167 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr20:7,768,425...7,783,181
Ensembl chr20:7,753,072...7,783,181
|
|
| G
|
Ccdc171
|
coiled-coil domain containing 171
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CCDC171 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:102,965,763...103,449,740
Ensembl chr 5:102,965,911...103,533,290
|
|
| G
|
Ccdc191
|
coiled-coil domain containing 191
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CCDC191 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr11:70,241,562...70,312,288
Ensembl chr11:70,241,562...70,312,431
|
|
| G
|
Ccdc71l
|
coiled-coil domain containing 71-like
|
increases expression
|
ISO
|
Nickel results in increased expression of CCDC71L mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 6:54,687,474...54,691,566
Ensembl chr 6:54,617,540...55,014,344
|
|
| G
|
Ccdc8
|
coiled-coil domain containing 8
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CCDC8 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:86,807,607...86,810,935
Ensembl chr 1:86,806,942...86,814,204
|
|
| G
|
Ccdc85a
|
coiled-coil domain containing 85A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CCDC85A mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr14:106,327,580...106,560,205
Ensembl chr14:106,327,580...106,560,165
|
|
| G
|
Ccdc88c
|
coiled-coil domain containing 88C
|
increases expression
|
ISO
|
Nickel results in increased expression of CCDC88C mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:125,899,337...126,019,162
Ensembl chr 6:125,899,526...126,018,865
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|
| G
|
Ccl11
|
C-C motif chemokine ligand 11
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of CCL11 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of CCL11 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr10:67,525,975...67,530,576
Ensembl chr10:67,525,862...67,530,575
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|
| G
|
Ccl12
|
C-C motif chemokine ligand 12
|
increases expression
|
ISO
|
Nickel results in increased expression of CCL13 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:67,567,876...67,569,426
Ensembl chr10:67,567,876...67,569,426
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|
| G
|
Ccl17
|
C-C motif chemokine ligand 17
|
multiple interactions increases expression
|
ISO
|
[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CCL17 mRNA; TNF protein inhibits the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CCL17 mRNA] Nickel results in increased expression of CCL17 mRNA
|
CTD |
PMID:23503329 PMID:24768652 PMID:25583101 |
|
NCBI chr19:10,208,120...10,218,340
Ensembl chr19:10,208,120...10,209,895
|
|
| G
|
Ccl19
|
C-C motif chemokine ligand 19
|
multiple interactions increases expression
|
ISO
|
[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CCL19 mRNA; TNF protein inhibits the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CCL19 mRNA] Nickel results in increased expression of CCL19 mRNA
|
CTD |
PMID:23503329 PMID:24768652 PMID:25583101 |
|
NCBI chr 5:61,759,220...61,761,164
Ensembl chr 5:61,759,220...61,772,022
|
|
| G
|
Ccl2
|
C-C motif chemokine ligand 2
|
multiple interactions decreases expression increases expression increases secretion
|
EXP ISO
|
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [PDGFB protein promotes the reaction [Nickel analog results in increased expression of CCL2 mRNA]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [PDGFB protein promotes the reaction [Nickel analog results in increased expression of CCL2 protein]]; Acetylcysteine inhibits the reaction [PDGFB protein promotes the reaction [Nickel analog results in increased expression of CCL2 protein]]; PDGFB protein promotes the reaction [Nickel analog results in increased expression of CCL2 mRNA]; PDGFB protein promotes the reaction [Nickel analog results in increased expression of CCL2 protein] [Asbestos, Serpentine results in increased abundance of [Magnesium co-treated with Chromium co-treated with Nickel co-treated with Cobalt]] which results in increased expression of CCL2 mRNA Nickel analog results in decreased expression of CCL2 mRNA Nickel results in increased expression of CCL2 mRNA Nickel results in increased secretion of CCL2 protein [TBX21 gene mutant form results in increased susceptibility to Nickel analog] which results in increased expression of CCL2 protein; [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CCL2 mRNA; [Zinc co-treated with Nickel co-treated with Cobalt] affects the reaction [Dietary Fats affects the expression of CCL2 mRNA]; CCL2 protein affects the reaction [[TBX21 gene mutant form results in increased susceptibility to Nickel analog] which results in increased expression of MUC5AC mRNA]; CCL2 protein affects the reaction [TBX21 gene mutant form results in increased susceptibility to Nickel analog]; TNF protein promotes the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CCL2 mRNA] Nickel analog results in increased expression of CCL2 mRNA; Nickel analog results in increased expression of CCL2 protein
|
CTD |
PMID:22700867 PMID:23503329 PMID:24499286 PMID:24840272 PMID:25144474 PMID:25583101 PMID:38605572 More...
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|
NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
|
|
| G
|
Ccl20
|
C-C motif chemokine ligand 20
|
multiple interactions increases expression
|
ISO
|
[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CCL20 mRNA; TNF protein promotes the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CCL20 mRNA] Nickel results in increased expression of CCL20 mRNA
|
CTD |
PMID:23195993 PMID:23503329 PMID:24768652 |
|
NCBI chr 9:91,837,139...91,839,736
Ensembl chr 9:91,836,946...91,839,736
|
|
| G
|
Ccl21
|
C-C motif chemokine ligand 21
|
increases expression
|
ISO
|
Nickel results in increased expression of CCL21 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:61,776,411...61,777,515
Ensembl chr 5:61,776,413...61,777,540
|
|
| G
|
Ccl22
|
C-C motif chemokine ligand 22
|
increases expression
|
ISO
|
Nickel results in increased expression of CCL22 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr19:10,263,589...10,270,359
Ensembl chr19:10,263,589...10,270,359
|
|
| G
|
Ccl24
|
C-C motif chemokine ligand 24
|
multiple interactions
|
ISO
|
[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CCL24 mRNA
|
CTD |
PMID:23503329 |
|
NCBI chr12:26,737,423...26,741,420
Ensembl chr12:26,737,439...26,750,924
|
|
| G
|
Ccl25
|
C-C motif chemokine ligand 25
|
multiple interactions
|
ISO
|
[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CCL25 mRNA
|
CTD |
PMID:23503329 |
|
NCBI chr12:7,505,231...7,514,402
Ensembl chr12:7,505,235...7,514,385
|
|
| G
|
Ccl26
|
C-C motif chemokine ligand 26
|
increases expression
|
ISO
|
Nickel results in increased expression of CCL26 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr12:26,745,972...26,750,924
|
|
| G
|
Ccl27
|
C-C motif chemokine ligand 27
|
multiple interactions
|
ISO
|
[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CCL27 mRNA
|
CTD |
PMID:23503329 |
|
NCBI chr 5:61,737,261...61,744,375
Ensembl chr 5:61,737,261...61,743,522
|
|
| G
|
Ccl28
|
C-C motif chemokine ligand 28
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CCL28 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 2:53,334,071...53,358,709
Ensembl chr 2:53,334,071...53,358,709
|
|
| G
|
Ccl3
|
C-C motif chemokine ligand 3
|
multiple interactions increases expression
|
EXP ISO
|
[Nickel co-treated with Cobalt co-treated with Tungsten] results in increased expression of CCL3 mRNA; [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of CCL3 mRNA Nickel results in increased expression of CCL3 mRNA Nickel results in increased expression of and results in increased secretion of CCL3 protein
|
CTD |
PMID:22198552 PMID:23624239 |
|
NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439
|
|
| G
|
Ccl4
|
C-C motif chemokine ligand 4
|
multiple interactions increases expression
|
EXP ISO
|
[Nickel co-treated with Cobalt co-treated with Tungsten] results in increased expression of CCL4 mRNA Nickel results in increased expression of CCL4 mRNA
|
CTD |
PMID:22198552 PMID:23195993 PMID:25583101 |
|
NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,950,289...68,965,722
|
|
| G
|
Ccl5
|
C-C motif chemokine ligand 5
|
multiple interactions increases expression
|
ISO
|
[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CCL5 mRNA Nickel results in increased expression of CCL5 mRNA
|
CTD |
PMID:23503329 PMID:24768652 PMID:25583101 |
|
NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884
|
|
| G
|
Ccl7
|
C-C motif chemokine ligand 7
|
multiple interactions increases expression
|
ISO
|
[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CCL7 mRNA; TNF protein promotes the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CCL7 mRNA] Nickel results in increased expression of CCL7 mRNA
|
CTD |
PMID:23503329 PMID:24768652 PMID:25583101 |
|
NCBI chr10:67,514,095...67,515,945
Ensembl chr10:67,514,091...67,515,947
|
|
| G
|
Ccm2
|
CCM2 scaffold protein
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CCM2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr14:85,632,338...85,678,016
Ensembl chr14:85,632,001...85,678,028
|
|
| G
|
Ccm2l
|
CCM2 like scaffold protein
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CCM2L mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:161,993,717...162,009,372
Ensembl chr 3:161,859,312...162,009,371
|
|
| G
|
Ccn1
|
cellular communication network factor 1
|
increases expression
|
ISO
|
Nickel results in increased expression of CCN1 mRNA
|
CTD |
PMID:12540486 PMID:24768652 PMID:25583101 |
|
NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:237,222,432...237,225,883
|
|
| G
|
Ccna1
|
cyclin A1
|
multiple interactions increases expression
|
ISO
|
[Nickel co-treated with austenitic steel analog] results in increased expression of CCNA1 mRNA Nickel results in increased expression of CCNA1 mRNA
|
CTD |
PMID:23638002 PMID:24768652 PMID:25583101 |
|
NCBI chr 2:141,383,352...141,428,205
Ensembl chr 2:141,382,468...141,393,300
|
|
| G
|
Ccna2
|
cyclin A2
|
increases expression
|
ISO
|
Nickel results in increased expression of CCNA2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701
|
|
| G
|
Ccnb1
|
cyclin B1
|
increases expression
|
ISO
|
Nickel results in increased expression of CCNB1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225
|
|
| G
|
Ccnb2
|
cyclin B2
|
increases expression
|
ISO
|
Nickel results in increased expression of CCNB2 mRNA
|
CTD |
PMID:19031421 |
|
NCBI chr 8:79,968,459...79,981,717
Ensembl chr 8:79,968,465...79,981,682
|
|
| G
|
Ccnd1
|
cyclin D1
|
multiple interactions
|
ISO
|
[Nickel co-treated with austenitic steel analog] results in decreased expression of CCND1 mRNA
|
CTD |
PMID:23638002 |
|
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
|
|
| G
|
Ccnd2
|
cyclin D2
|
increases expression
|
ISO
|
Nickel results in increased expression of CCND2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:161,653,048...161,675,422
Ensembl chr 4:161,653,048...161,680,301 Ensembl chr 4:161,653,048...161,680,301
|
|
| G
|
Ccnd3
|
cyclin D3
|
increases expression
|
ISO
|
Nickel results in increased expression of CCND3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:20,891,696...20,987,199
Ensembl chr 9:20,891,704...20,987,033
|
|
| G
|
Ccne1
|
cyclin E1
|
increases expression
|
ISO
|
Nickel results in increased expression of CCNE1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:99,918,674...99,927,822
|
|
| G
|
Ccne2
|
cyclin E2
|
multiple interactions increases expression
|
ISO
|
[Nickel co-treated with austenitic steel analog] results in increased expression of CCNE2 mRNA Nickel results in increased expression of CCNE2 mRNA
|
CTD |
PMID:23638002 PMID:25583101 |
|
NCBI chr 5:29,082,169...29,094,879
Ensembl chr 5:29,082,703...29,094,882
|
|
| G
|
Ccng2
|
cyclin G2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CCNG2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:15,088,694...15,097,190
Ensembl chr14:15,088,695...15,096,206
|
|
| G
|
Ccnyl1
|
cyclin Y-like 1
|
increases expression
|
ISO
|
Nickel results in increased expression of CCNYL1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:73,565,484...73,601,926
Ensembl chr 9:73,565,402...73,601,922
|
|
| G
|
Ccpg1
|
cell cycle progression 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CCPG1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:82,600,677...82,633,082
Ensembl chr 8:82,600,536...82,660,246
|
|
| G
|
Ccr1
|
C-C motif chemokine receptor 1
|
increases expression
|
ISO
|
Nickel results in increased expression of CCR1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:132,433,711...132,439,266
Ensembl chr 8:132,431,592...132,439,374
|
|
| G
|
Ccr2
|
C-C motif chemokine receptor 2
|
multiple interactions increases expression decreases expression affects expression
|
ISO
|
trichostatin A inhibits the reaction [Nickel affects the expression of CCR2 mRNA] Nickel results in increased expression of CCR2 mRNA Nickel results in decreased expression of CCR2 mRNA
|
CTD |
PMID:14575637 PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 8:132,611,883...132,619,106
Ensembl chr 8:132,611,410...132,620,059
|
|
| G
|
Ccr4
|
C-C motif chemokine receptor 4
|
increases expression
|
ISO
|
Nickel results in increased expression of CCR4 mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr 8:123,054,505...123,060,244
Ensembl chr 8:123,054,324...123,077,642
|
|
| G
|
Ccr5
|
C-C motif chemokine receptor 5
|
affects expression increases expression multiple interactions
|
ISO
|
Nickel affects the expression of CCR5 mRNA Nickel results in increased expression of CCR5 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of CCR5 mRNA]
|
CTD |
PMID:14575637 PMID:25583101 |
|
NCBI chr 8:132,629,097...132,660,980
Ensembl chr 8:132,629,683...132,637,594
|
|
| G
|
Ccr6
|
C-C motif chemokine receptor 6
|
decreases expression increases expression multiple interactions
|
ISO
|
Nickel results in decreased expression of CCR6 mRNA Nickel results in increased expression of CCR6 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of CCR6 mRNA]
|
CTD |
PMID:14575637 PMID:25583101 |
|
NCBI chr 1:55,022,037...55,055,857
Ensembl chr 1:55,021,833...55,046,059
|
|
| G
|
Ccr7
|
C-C motif chemokine receptor 7
|
increases expression
|
ISO
|
Nickel results in increased expression of CCR7 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:84,594,399...84,604,514
Ensembl chr10:84,593,594...84,604,501
|
|
| G
|
Ccrl2
|
C-C motif chemokine receptor like 2
|
increases expression
|
ISO
|
Nickel results in increased expression of CCRL2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:119,912,671...119,915,313
Ensembl chr 8:119,911,288...119,922,380
|
|
| G
|
Cct5
|
chaperonin containing TCP1 subunit 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CCT5 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 2:84,302,621...84,313,773
Ensembl chr 2:84,302,623...84,313,779
|
|
| G
|
Cd14
|
CD14 molecule
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of CD14 mRNA Nickel results in increased expression of CD14 mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292
|
|
| G
|
Cd160
|
CD160 molecule
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CD160 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 2:187,029,654...187,042,447
Ensembl chr 2:187,033,140...187,064,587
|
|
| G
|
Cd163
|
CD163 molecule
|
increases expression multiple interactions
|
ISO
|
Nickel results in increased expression of CD163 mRNA [Asbestos, Serpentine results in increased abundance of [Magnesium co-treated with Chromium co-treated with Nickel co-treated with Cobalt]] which results in increased expression of CD163 mRNA
|
CTD |
PMID:24768652 PMID:25583101 PMID:38605572 |
|
NCBI chr 4:158,770,751...158,804,146
Ensembl chr 4:158,770,749...158,804,146
|
|
| G
|
Cd180
|
CD180 molecule
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of CD180 mRNA Nickel results in increased expression of CD180 mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 2:35,589,889...35,602,837
Ensembl chr 2:35,589,451...35,603,982
|
|
| G
|
Cd1d1
|
CD1d1 molecule
|
increases expression
|
ISO
|
Nickel results in increased expression of CD1D mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:174,721,522...174,725,029
Ensembl chr 2:174,721,522...174,725,029
|
|
| G
|
Cd2
|
Cd2 molecule
|
increases expression
|
ISO
|
Nickel results in increased expression of CD2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:191,399,510...191,412,659
Ensembl chr 2:191,399,510...191,413,665
|
|
| G
|
Cd200
|
Cd200 molecule
|
decreases expression multiple interactions
|
ISO EXP
|
Nickel results in decreased expression of CD200 mRNA [nickel sulfate results in increased abundance of Nickel] which results in decreased expression of CD200 mRNA
|
CTD |
PMID:25583101 PMID:31734292 |
|
NCBI chr11:68,916,200...68,943,570
Ensembl chr11:68,916,224...68,943,569
|
|
| G
|
Cd200r1
|
CD200 receptor 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CD200R1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr11:69,392,943...69,427,213
Ensembl chr11:69,392,975...69,427,128
|
|
| G
|
Cd209d
|
CD209d molecule
|
increases expression
|
ISO
|
Nickel results in increased expression of CD209 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr12:6,689,002...6,695,452
Ensembl chr12:6,689,002...6,698,976
|
|
| G
|
Cd226
|
CD226 molecule
|
increases expression
|
ISO
|
Nickel results in increased expression of CD226 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr18:84,723,330...84,819,836
Ensembl chr18:84,725,242...84,819,835
|
|
| G
|
Cd24
|
CD24 molecule
|
increases expression
|
ISO
|
Nickel results in increased expression of CD24 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr20:48,655,549...48,661,786
Ensembl chr20:48,655,805...48,661,785
|
|
| G
|
Cd244
|
CD244 molecule
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CD244 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr13:86,583,727...86,606,902
Ensembl chr13:86,584,826...86,616,009
|
|
| G
|
Cd247
|
Cd247 molecule
|
increases expression
|
ISO
|
Nickel results in increased expression of CD247 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:80,576,264...80,651,422
Ensembl chr13:80,576,202...80,655,248
|
|
| G
|
Cd27
|
CD27 molecule
|
increases expression
|
ISO
|
Nickel results in increased expression of CD27 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:159,716,932...159,721,823
Ensembl chr 4:159,716,935...159,721,823
|
|
| G
|
Cd274
|
CD274 molecule
|
increases expression
|
ISO
|
Nickel results in increased expression of CD274 mRNA; Nickel results in increased expression of CD274 protein
|
CTD |
PMID:23624239 PMID:24768652 PMID:25583101 |
|
NCBI chr 1:236,526,215...236,549,956
Ensembl chr 1:236,496,463...236,549,951
|
|
| G
|
Cd28
|
Cd28 molecule
|
increases expression
|
ISO
|
Nickel results in increased expression of CD28 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 9:69,660,316...69,689,192
Ensembl chr 9:69,545,326...69,689,192
|
|
| G
|
Cd300a
|
Cd300a molecule
|
increases expression
|
ISO
|
Nickel results in increased expression of CD300A mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:100,428,826...100,441,693
Ensembl chr10:100,428,826...100,442,958
|
|
| G
|
Cd300lg
|
Cd300 molecule-like family member G
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CD300LG mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:87,492,078...87,509,452
Ensembl chr10:87,492,106...87,508,585
|
|
| G
|
Cd33
|
CD33 molecule
|
increases expression
|
ISO
|
Nickel results in increased expression of CD33 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:103,071,985...103,086,687
Ensembl chr 1:103,072,375...103,086,291
|
|
| G
|
Cd34
|
CD34 molecule
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CD34 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:109,008,786...109,029,317
Ensembl chr13:109,008,623...109,029,315
|
|
| G
|
Cd36
|
CD36 molecule
|
increases expression decreases expression
|
ISO
|
Nickel results in increased expression of CD36 mRNA Nickel results in decreased expression of CD36 mRNA
|
CTD |
PMID:20053437 PMID:24768652 PMID:25583101 |
|
NCBI chr 4:18,209,088...18,302,142
|
|
| G
|
Cd37
|
CD37 molecule
|
increases expression
|
ISO
|
Nickel results in increased expression of CD37 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:104,855,622...104,861,111
Ensembl chr 1:104,849,166...104,861,276
|
|
| G
|
Cd38
|
CD38 molecule
|
increases expression
|
ISO
|
Nickel results in increased expression of CD38 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr14:71,384,532...71,424,794
Ensembl chr14:71,384,532...71,424,505
|
|
| G
|
Cd3d
|
CD3 delta subunit of T-cell receptor complex
|
increases expression
|
ISO
|
Nickel results in increased expression of CD3D mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:54,184,573...54,190,112
Ensembl chr 8:54,175,155...54,196,722
|
|
| G
|
Cd3e
|
CD3 epsilon subunit of T-cell receptor complex
|
increases expression
|
ISO
|
Nickel results in increased expression of CD3E mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:54,200,617...54,211,770
Ensembl chr 8:54,200,617...54,211,876
|
|
| G
|
Cd3g
|
CD3 gamma subunit of T-cell receptor complex
|
increases expression
|
ISO
|
Nickel results in increased expression of CD3G mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:54,177,572...54,184,087
Ensembl chr 8:54,177,977...54,183,918
|
|
| G
|
Cd4
|
Cd4 molecule
|
increases expression
|
ISO
|
Nickel results in increased expression of CD4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:159,355,147...159,381,636
Ensembl chr 4:159,356,337...159,381,461
|
|
| G
|
Cd40
|
CD40 molecule
|
increases expression
|
ISO
|
Nickel results in increased expression of CD40 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:174,209,719...174,224,847
|
|
| G
|
Cd44
|
CD44 molecule
|
multiple interactions increases expression affects expression
|
ISO
|
trichostatin A inhibits the reaction [Nickel affects the expression of CD44 mRNA] Nickel results in increased expression of CD44 mRNA
|
CTD |
PMID:14575637 PMID:24768652 PMID:25583101 |
|
NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:109,612,054...109,699,424
|
|
| G
|
Cd46
|
CD46 molecule
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of CD46 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of CD46 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr13:109,104,122...109,134,903
|
|
| G
|
Cd47
|
Cd47 molecule
|
increases expression
|
ISO
|
Nickel results in increased expression of CD47 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:64,374,816...64,438,763
Ensembl chr11:64,377,926...64,438,272
|
|
| G
|
Cd48
|
Cd48 molecule
|
increases expression
|
ISO
|
Nickel results in increased expression of CD48 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:86,717,960...86,741,540
Ensembl chr13:86,717,961...86,742,942
|
|
| G
|
Cd5
|
Cd5 molecule
|
increases expression
|
ISO
|
Nickel results in increased expression of CD5 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:216,790,245...216,811,209
Ensembl chr 1:216,790,245...216,811,209
|
|
| G
|
Cd52
|
CD52 molecule
|
increases expression
|
ISO
|
Nickel results in increased expression of CD52 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:151,603,537...151,605,096
Ensembl chr 5:151,603,524...151,605,086
|
|
| G
|
Cd6
|
Cd6 molecule
|
increases expression
|
ISO
|
Nickel results in increased expression of CD6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:216,867,767...216,906,642
Ensembl chr 1:216,867,771...216,879,432
|
|
| G
|
Cd69
|
Cd69 molecule
|
increases expression
|
ISO
|
Nickel results in increased expression of CD69 mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr 4:164,411,485...164,419,403
Ensembl chr 4:164,411,485...164,419,509
|
|
| G
|
Cd80
|
Cd80 molecule
|
increases response to substance increases expression
|
ISO
|
CD80 protein results in increased susceptibility to Nickel Nickel results in increased expression of CD80 mRNA
|
CTD |
PMID:19844976 PMID:25583101 |
|
NCBI chr11:75,760,073...75,798,978
Ensembl chr11:75,760,147...75,797,540
|
|
| G
|
Cd83
|
CD83 molecule
|
increases expression
|
ISO
|
Nickel results in increased expression of CD83 mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr17:21,093,281...21,113,223
Ensembl chr17:21,093,281...21,113,047
|
|
| G
|
Cd84
|
CD84 molecule
|
increases expression
|
ISO
|
Nickel results in increased expression of CD84 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:86,859,979...86,899,984
Ensembl chr13:86,859,990...86,894,318
|
|
| G
|
Cd86
|
CD86 molecule
|
increases response to substance increases expression
|
ISO
|
CD86 protein results in increased susceptibility to Nickel Nickel results in increased expression of CD86 mRNA; Nickel results in increased expression of CD86 protein
|
CTD |
PMID:19033392 PMID:19844976 PMID:23624239 PMID:24768652 PMID:25583101 |
|
NCBI chr11:77,647,565...77,706,178
Ensembl chr11:77,647,600...77,725,361
|
|
| G
|
Cd8a
|
CD8 subunit alpha
|
increases expression
|
ISO
|
Nickel results in increased expression of CD8A mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:104,924,116...104,928,353
Ensembl chr 4:104,900,833...104,928,358
|
|
| G
|
Cd8b
|
CD8 subunit beta
|
increases expression
|
ISO
|
Nickel results in increased expression of CD8B mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:104,870,911...104,886,838
Ensembl chr 4:104,870,893...104,886,868
|
|
| G
|
Cd93
|
CD93 molecule
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of CD93 mRNA Nickel results in increased expression of CD93 mRNA
|
CTD |
PMID:23195993 PMID:24768652 |
|
NCBI chr 3:156,345,019...156,351,537
Ensembl chr 3:156,345,019...156,351,537
|
|
| G
|
Cd96
|
CD96 molecule
|
increases expression
|
ISO
|
Nickel results in increased expression of CD96 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:68,164,926...68,239,266
Ensembl chr11:68,164,872...68,241,937
|
|
| G
|
Cdc14a
|
cell division cycle 14A
|
increases expression
|
ISO
|
Nickel results in increased expression of CDC14A mRNA
|
CTD |
PMID:18922574 |
|
NCBI chr 2:206,910,475...207,070,537
Ensembl chr 2:206,910,475...207,091,722
|
|
| G
|
Cdc20
|
cell division cycle 20
|
affects binding
|
ISO
|
Nickel binds to CDC20 protein
|
CTD |
PMID:16497171 |
|
NCBI chr 5:137,251,596...137,255,799
Ensembl chr 5:137,251,596...137,255,799
|
|
| G
|
Cdc25a
|
cell division cycle 25A
|
increases expression
|
ISO
|
Nickel results in increased expression of CDC25A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:118,742,824...118,761,190
Ensembl chr 8:118,742,426...118,761,188
|
|
| G
|
Cdc25b
|
cell division cycle 25B
|
increases expression
|
ISO
|
Nickel results in increased expression of CDC25B mRNA
|
CTD |
PMID:19031421 PMID:25583101 |
|
NCBI chr 3:138,860,148...138,870,287
Ensembl chr 3:138,860,130...138,870,492
|
|
| G
|
Cdc42ep2
|
CDC42 effector protein 2
|
increases expression
|
ISO
|
Nickel results in increased expression of CDC42EP2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 1:212,631,317...212,640,231
Ensembl chr 1:212,629,881...212,640,234
|
|
| G
|
Cdc42se1
|
CDC42 small effector 1
|
increases expression
|
ISO
|
Nickel results in increased expression of CDC42SE1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 2:185,494,692...185,502,519
Ensembl chr 2:185,496,547...185,502,514
|
|
| G
|
Cdc42se2
|
CDC42 small effector 2
|
increases expression
|
ISO
|
Nickel results in increased expression of CDC42SE2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:39,337,269...39,405,772
Ensembl chr 1:100,424,547...100,424,801 Ensembl chr10:100,424,547...100,424,801
|
|
| G
|
Cdc45
|
cell division cycle 45
|
increases expression
|
ISO
|
Nickel results in increased expression of CDC45 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr11:95,689,702...95,714,980
Ensembl chr11:95,689,919...95,714,981
|
|
| G
|
Cdc5l
|
cell division cycle 5-like
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CDC5L mRNA
|
CTD |
PMID:18922574 |
|
NCBI chr 9:23,062,397...23,100,901
Ensembl chr 9:23,062,205...23,100,899
|
|
| G
|
Cdc7
|
cell division cycle 7
|
increases expression
|
ISO
|
Nickel results in increased expression of CDC7 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr14:2,949,538...2,969,656
Ensembl chr14:2,949,539...2,969,656
|
|
| G
|
Cdca2
|
cell division cycle associated 2
|
increases expression
|
ISO
|
Nickel results in increased expression of CDCA2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr15:46,071,360...46,117,524
Ensembl chr15:46,071,360...46,116,639
|
|
| G
|
Cdca5
|
cell division cycle associated 5
|
increases expression
|
ISO
|
Nickel results in increased expression of CDCA5 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:212,807,863...212,821,313
Ensembl chr 1:212,804,014...212,821,309
|
|
| G
|
Cdca8
|
cell division cycle associated 8
|
increases expression
|
ISO
|
Nickel results in increased expression of CDCA8 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:142,461,082...142,483,336
Ensembl chr 5:142,461,084...142,483,283
|
|
| G
|
Cdcp1
|
CUB domain containing protein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of CDCP1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:131,706,140...131,742,799
Ensembl chr 8:131,706,140...131,742,877
|
|
| G
|
Cdh1
|
cadherin 1
|
multiple interactions
|
ISO
|
[nickel chloride results in increased abundance of Nickel] which results in decreased expression of CDH1 mRNA; [nickel chloride results in increased abundance of Nickel] which results in decreased expression of CDH1 protein; Acetylcysteine inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in decreased expression of CDH1 protein]
|
CTD |
PMID:38488660 |
|
NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565
|
|
| G
|
Cdh13
|
cadherin 13
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CDH13 mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr19:63,258,251...64,296,122
Ensembl chr19:63,258,122...64,296,119
|
|
| G
|
Cdh19
|
cadherin 19
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CDH19 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:28,450,361...28,561,932
Ensembl chr13:28,451,283...28,533,753
|
|
| G
|
Cdh2
|
cadherin 2
|
multiple interactions
|
ISO
|
[nickel chloride results in increased abundance of Nickel] which results in increased expression of CDH2 mRNA; [nickel chloride results in increased abundance of Nickel] which results in increased expression of CDH2 protein; Acetylcysteine inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of CDH2 protein]
|
CTD |
PMID:38488660 |
|
NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288
|
|
| G
|
Cdh3
|
cadherin 3
|
increases expression
|
ISO
|
Nickel results in increased expression of CDH3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr19:51,303,414...51,353,900
Ensembl chr19:51,300,083...51,354,257
|
|
| G
|
Cdh6
|
cadherin 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CDH6 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 2:63,801,630...63,952,309
Ensembl chr 2:63,806,135...63,952,287
|
|
| G
|
Cdk1
|
cyclin-dependent kinase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of CDK1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455
|
|
| G
|
Cdk15
|
cyclin-dependent kinase 15
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CDK15 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:68,205,759...68,299,218
Ensembl chr 9:68,205,678...68,293,579
|
|
| G
|
Cdk19
|
cyclin-dependent kinase 19
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CDK19 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr20:45,324,911...45,465,121
Ensembl chr20:45,324,862...45,465,121
|
|
| G
|
Cdk2
|
cyclin dependent kinase 2
|
increases expression
|
ISO
|
Nickel results in increased expression of CDK2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878
|
|
| G
|
Cdk2ap2
|
cyclin-dependent kinase 2 associated protein 2
|
increases expression
|
ISO
|
Nickel results in increased expression of CDK2AP2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:210,819,155...210,822,604
Ensembl chr 1:210,820,507...210,823,010
|
|
| G
|
Cdk4
|
cyclin-dependent kinase 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CDK4 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163
|
|
| G
|
Cdk5r1
|
cyclin-dependent kinase 5 regulatory subunit 1
|
increases expression
|
ISO
|
Nickel results in increased expression of CDK5R1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:65,981,692...65,985,831
Ensembl chr10:65,978,911...65,989,272
|
|
| G
|
Cdkl2
|
cyclin dependent kinase like 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CDKL2 mRNA
|
CTD |
PMID:12540486 PMID:24768652 PMID:25583101 |
|
NCBI chr14:16,312,154...16,347,524
Ensembl chr14:16,312,932...16,347,523
|
|
| G
|
Cdkl3
|
cyclin-dependent kinase-like 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CDKL3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:36,755,413...36,850,197
Ensembl chr10:36,764,377...36,878,660
|
|
| G
|
Cdkn1a
|
cyclin-dependent kinase inhibitor 1A
|
multiple interactions increases expression
|
EXP ISO
|
[Nickel co-treated with Cobalt co-treated with Tungsten] results in increased expression of CDKN1A mRNA; [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of CDKN1A mRNA Nickel results in increased expression of CDKN1A mRNA TP53 protein affects the reaction [Nickel results in increased expression of CDKN1A mRNA]
|
CTD |
PMID:12540486 PMID:22198552 PMID:24068677 |
|
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
|
|
| G
|
Cdkn1c
|
cyclin-dependent kinase inhibitor 1C
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CDKN1C mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:208,084,801...208,087,680
Ensembl chr 1:208,084,787...208,087,498
|
|
| G
|
Cdkn2c
|
cyclin-dependent kinase inhibitor 2C
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CDKN2C mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:129,639,736...129,645,564
Ensembl chr 5:129,639,736...129,644,891
|
|
| G
|
Cdkn3
|
cyclin-dependent kinase inhibitor 3
|
increases expression
|
ISO
|
Nickel results in increased expression of CDKN3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr15:22,502,299...22,513,725
Ensembl chr15:22,502,382...22,513,722
|
|
| G
|
Cdon
|
cell adhesion associated, oncogene regulated
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CDON mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 8:42,032,921...42,119,451
Ensembl chr 8:42,033,042...42,119,345
|
|
| G
|
Cdt1
|
chromatin licensing and DNA replication factor 1
|
increases expression
|
ISO
|
Nickel results in increased expression of CDT1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr19:67,529,249...67,534,195
Ensembl chr19:67,529,201...67,534,194
|
|
| G
|
Cdx4
|
caudal type homeo box 4
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of CDX4 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of CDX4 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr X:72,392,653...72,401,239
Ensembl chr X:72,392,653...72,401,239
|
|
| G
|
Ceacam6
|
CEA cell adhesion molecule 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CEACAM6 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:89,544,415...89,562,552
Ensembl chr 1:89,544,400...89,562,552
|
|
| G
|
Cebpb
|
CCAAT/enhancer binding protein beta
|
multiple interactions
|
ISO
|
2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide inhibits the reaction [[Nickel co-treated with lipopolysaccharide, E. coli O26-B6] results in increased expression of CEBPB protein]; [Nickel co-treated with lipopolysaccharide, E. coli O26-B6] results in increased expression of CEBPB protein; N'-(7-fluoroH-pyrrolo(1,2-a)quinoxalin-4-yl)pyrazine-2-carbohydrazide promotes the reaction [[Nickel co-treated with lipopolysaccharide, E. coli O26-B6] results in increased expression of CEBPB protein]
|
CTD |
PMID:35623502 |
|
NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:176,816,859...176,838,072
|
|
| G
|
Cebpd
|
CCAAT/enhancer binding protein delta
|
increases expression
|
ISO
|
Nickel results in increased expression of CEBPD mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr11:98,268,856...98,269,994
Ensembl chr11:98,265,651...98,280,824
|
|
| G
|
Celf2
|
CUGBP, Elav-like family member 2
|
increases expression
|
ISO
|
Nickel results in increased expression of CELF2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr17:75,813,928...76,639,300
Ensembl chr17:75,813,704...76,636,362
|
|
| G
|
Celf6
|
CUGBP, Elav-like family member 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CELF6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:68,870,902...68,901,863
Ensembl chr 8:68,871,093...68,901,863
|
|
| G
|
Cemip
|
cell migration inducing hyaluronidase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of CEMIP mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:147,316,052...147,471,552
Ensembl chr 1:147,316,052...147,471,768
|
|
| G
|
Cemip2
|
cell migration inducing hyaluronidase 2
|
increases expression
|
ISO
|
Nickel results in increased expression of CEMIP2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:228,756,826...228,834,313
Ensembl chr 1:228,757,466...228,832,906
|
|
| G
|
Cenpe
|
centromere protein E
|
increases expression
|
ISO
|
Nickel results in increased expression of CENPE mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:226,310,970...226,369,636
Ensembl chr 2:226,300,798...226,369,636
|
|
| G
|
Cenpk
|
centromere protein K
|
increases expression
|
ISO
|
Nickel results in increased expression of CENPK mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:37,094,163...37,155,158
Ensembl chr 2:37,094,248...37,119,488
|
|
| G
|
Cenpn
|
centromere protein N
|
increases expression
|
ISO
|
Nickel results in increased expression of CENPN mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr19:61,880,101...61,902,850
Ensembl chr19:61,877,148...61,902,918
|
|
| G
|
Cenpv
|
centromere protein V
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CENPV mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:47,713,778...47,746,800
Ensembl chr10:47,713,778...47,727,679
|
|
| G
|
Cenpw
|
centromere protein W
|
increases expression
|
ISO
|
Nickel results in increased expression of CENPW mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:29,353,939...29,359,109
Ensembl chr 1:29,353,970...29,359,109
|
|
| G
|
Cep126
|
centrosomal protein 126
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CEP126 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:13,485,211...13,552,711
Ensembl chr 8:13,490,685...13,552,221
|
|
| G
|
Cep55
|
centrosomal protein 55
|
increases expression
|
ISO
|
Nickel results in increased expression of CEP55 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:245,245,272...245,260,835
Ensembl chr 1:245,245,306...245,260,890
|
|
| G
|
Cep68
|
centrosomal protein 68
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CEP68 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr14:98,649,993...98,671,892
Ensembl chr14:98,649,993...98,671,868
|
|
| G
|
Cep70
|
centrosomal protein 70
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CEP70 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:108,689,562...108,742,620
Ensembl chr 8:108,689,671...108,742,617
|
|
| G
|
Cep95
|
centrosomal protein 95
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CEP95 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:92,231,829...92,259,813
Ensembl chr10:92,231,512...92,259,810
|
|
| G
|
Cercam
|
cerebral endothelial cell adhesion molecule
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CERCAM mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 3:33,515,513...33,553,817
Ensembl chr 3:33,486,664...33,553,813
|
|
| G
|
Ces1d
|
carboxylesterase 1D
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CES1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr19:30,046,494...30,085,039
Ensembl chr19:30,046,449...30,085,449
|
|
| G
|
Ces4a
|
carboxylesterase 4A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CES4A mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr19:49,921,643...49,942,838
Ensembl chr19:49,921,608...49,939,461
|
|
| G
|
Cfap20
|
cilia and flagella associated protein 20
|
increases expression
|
ISO
|
Nickel results in increased expression of CFAP20 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr19:9,614,265...9,628,612
Ensembl chr19:9,614,721...9,628,612
|
|
| G
|
Cfap70
|
cilia and flagella associated protein 70
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CFAP70 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr15:3,901,544...3,967,224
Ensembl chr15:3,901,610...3,967,220
|
|
| G
|
Cfap91
|
cilia and flagella associated protein 91
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CFAP91 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:75,919,129...75,962,786
Ensembl chr11:75,919,142...75,962,785
|
|
| G
|
Cfb
|
complement factor B
|
affects binding increases expression
|
ISO
|
CFB protein binds to Nickel Nickel results in increased expression of CFB mRNA
|
CTD |
PMID:23896426 PMID:25583101 |
|
NCBI chr20:3,975,271...3,981,138
Ensembl chr20:3,955,776...3,981,740
|
|
| G
|
Cfh
|
complement factor H
|
affects binding
|
ISO
|
CFH protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr13:54,063,079...54,164,523
Ensembl chr13:54,062,531...54,164,532
|
|
| G
|
Cfi
|
complement factor I
|
affects binding
|
ISO
|
CFI protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr 2:221,062,206...221,104,790
Ensembl chr 2:221,062,212...221,104,786
|
|
| G
|
Cfl1
|
cofilin 1
|
increases expression
|
ISO
|
Nickel results in increased expression of CFL1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:212,227,124...212,230,656
Ensembl chr 1:212,226,121...212,231,353
|
|
| G
|
Cfl2
|
cofilin 2
|
increases expression
|
ISO
|
Nickel results in increased expression of CFL2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 6:78,090,843...78,094,888
Ensembl chr 6:78,090,843...78,094,888
|
|
| G
|
Cflar
|
CASP8 and FADD-like apoptosis regulator
|
increases expression
|
ISO
|
Nickel results in increased expression of CFLAR mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:67,679,502...67,747,226
Ensembl chr 9:67,679,559...67,726,434
|
|
| G
|
Cfp
|
complement factor properdin
|
increases expression
|
ISO
|
Nickel results in increased expression of CFP mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:3,715,551...3,721,113
Ensembl chr X:3,710,425...3,721,112
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|
| G
|
Cftr
|
CF transmembrane conductance regulator
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CFTR mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643
|
|
| G
|
Cgnl1
|
cingulin-like 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CGNL1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:81,154,169...81,305,598
Ensembl chr 8:81,140,091...81,305,747
|
|
| G
|
Ch25h
|
cholesterol 25-hydroxylase
|
increases expression
|
ISO
|
Nickel results in increased expression of CH25H mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:241,428,048...241,429,366
Ensembl chr 1:241,331,619...241,431,190
|
|
| G
|
Chac2
|
ChaC glutathione specific gamma-glutamylcyclotransferase 2
|
increases expression
|
ISO
|
Nickel results in increased expression of CHAC2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:108,921,669...108,929,215
Ensembl chr14:108,921,341...108,929,469
|
|
| G
|
Chdh
|
choline dehydrogenase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CHDH mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr16:5,199,738...5,232,067
Ensembl chr16:5,200,763...5,232,997
|
|
| G
|
Chek1
|
checkpoint kinase 1
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of CHEK1 mRNA Nickel results in increased expression of CHEK1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:44,609,417...44,629,867
Ensembl chr 8:44,609,417...44,629,359
|
|
| G
|
Chek2
|
checkpoint kinase 2
|
multiple interactions
|
EXP
|
[Nickel co-treated with Iron co-treated with Tungsten] results in decreased expression of CHEK2 mRNA
|
CTD |
PMID:22198552 |
|
NCBI chr12:51,448,838...51,481,159
Ensembl chr12:51,449,140...51,480,667
|
|
| G
|
Chga
|
chromogranin A
|
affects expression
|
EXP
|
Nickel affects the expression of CHGA mRNA
|
CTD |
PMID:18812211 |
|
NCBI chr 6:127,460,895...127,472,238
Ensembl chr 6:127,460,854...127,472,237
|
|
| G
|
Chgb
|
chromogranin B
|
increases expression
|
EXP
|
Nickel results in increased expression of CHGB mRNA
|
CTD |
PMID:18812211 |
|
NCBI chr 3:140,496,712...140,510,057
Ensembl chr 3:140,495,951...140,510,054
|
|
| G
|
Chl1
|
cell adhesion molecule L1-like
|
multiple interactions affects expression
|
ISO
|
trichostatin A inhibits the reaction [Nickel affects the expression of CHL1 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 4:137,847,648...138,062,077
Ensembl chr 4:137,847,895...138,062,077
|
|
| G
|
Chm
|
CHM Rab escort protein
|
increases expression
|
ISO
|
Nickel results in increased expression of CHM mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:82,395,463...82,554,249
Ensembl chr X:82,396,816...82,568,642
|
|
| G
|
Chn1
|
chimerin 1
|
increases expression
|
ISO
|
Nickel results in increased expression of CHN1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:78,917,329...79,084,040
Ensembl chr 3:78,917,329...79,084,197
|
|
| G
|
Chodl
|
chondrolectin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CHODL mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr11:31,141,030...31,163,342
Ensembl chr11:31,141,021...31,163,334
|
|
| G
|
Chp1
|
calcineurin-like EF-hand protein 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CHP1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 3:126,989,800...127,025,071
Ensembl chr 3:126,989,579...127,042,443
|
|
| G
|
Chp2
|
calcineurin-like EF hand protein 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CHP2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 1:186,189,090...186,203,663
Ensembl chr 1:186,185,151...186,203,667
|
|
| G
|
Chpt1
|
choline phosphotransferase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CHPT1 mRNA
|
CTD |
PMID:19031421 PMID:24768652 PMID:25583101 |
|
NCBI chr 7:24,753,880...24,802,529
Ensembl chr 7:24,750,343...24,802,521
|
|
| G
|
Chrm1
|
cholinergic receptor, muscarinic 1
|
decreases expression
|
EXP
|
Nickel results in decreased expression of CHRM1 mRNA
|
CTD |
PMID:18812211 |
|
NCBI chr 1:214,996,180...215,012,136
Ensembl chr 1:214,995,872...215,020,602
|
|
| G
|
Chrm2
|
cholinergic receptor, muscarinic 2
|
affects expression
|
EXP
|
Nickel affects the expression of CHRM2 mRNA
|
CTD |
PMID:18812211 |
|
NCBI chr 4:65,981,136...66,116,128
Ensembl chr 4:65,981,006...66,126,464
|
|
| G
|
Chrm3
|
cholinergic receptor, muscarinic 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CHRM3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr17:64,696,549...65,158,622
Ensembl chr17:64,696,066...65,173,304
|
|
| G
|
Chrm4
|
cholinergic receptor, muscarinic 4
|
decreases expression multiple interactions affects expression
|
EXP ISO
|
Nickel results in decreased expression of CHRM4 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of CHRM4 mRNA]
|
CTD |
PMID:14575637 PMID:18812211 |
|
NCBI chr 3:98,349,080...98,356,821
Ensembl chr 3:98,348,650...98,358,771
|
|
| G
|
Chrna10
|
cholinergic receptor nicotinic alpha 10 subunit
|
decreases expression
|
EXP
|
Nickel results in decreased expression of CHRNA10 mRNA
|
CTD |
PMID:18812211 |
|
NCBI chr 1:165,898,932...165,905,348
Ensembl chr 1:165,899,261...165,903,458
|
|
| G
|
Chrna2
|
cholinergic receptor nicotinic alpha 2 subunit
|
decreases expression
|
EXP
|
Nickel results in decreased expression of CHRNA2 mRNA
|
CTD |
PMID:18812211 |
|
NCBI chr15:44,517,862...44,534,144
Ensembl chr15:44,517,862...44,534,144
|
|
| G
|
Chrna3
|
cholinergic receptor nicotinic alpha 3 subunit
|
decreases expression
|
EXP
|
Nickel results in decreased expression of CHRNA3 mRNA
|
CTD |
PMID:18812211 |
|
NCBI chr 8:64,297,755...64,311,251
Ensembl chr 8:64,297,755...64,311,412
|
|
| G
|
Chrna4
|
cholinergic receptor nicotinic alpha 4 subunit
|
decreases expression
|
EXP
|
Nickel results in decreased expression of CHRNA4 mRNA
|
CTD |
PMID:18812211 |
|
NCBI chr 3:188,506,802...188,535,558
Ensembl chr 3:188,501,209...188,535,105
|
|
| G
|
Chrna7
|
cholinergic receptor nicotinic alpha 7 subunit
|
decreases expression
|
EXP
|
Nickel results in decreased expression of CHRNA7 mRNA
|
CTD |
PMID:18812211 |
|
NCBI chr 1:126,123,425...126,249,181
Ensembl chr 1:126,123,425...126,446,858
|
|
| G
|
Chrnb3
|
cholinergic receptor nicotinic beta 3 subunit
|
decreases expression
|
EXP
|
Nickel results in decreased expression of CHRNB3 mRNA
|
CTD |
PMID:18812211 |
|
NCBI chr16:71,411,847...71,454,225
Ensembl chr16:71,417,039...71,454,225
|
|
| G
|
Chrnb4
|
cholinergic receptor nicotinic beta 4 subunit
|
decreases expression
|
EXP
|
Nickel results in decreased expression of CHRNB4 mRNA
|
CTD |
PMID:18812211 |
|
NCBI chr 8:64,312,644...64,333,319
Ensembl chr 8:64,313,669...64,333,248
|
|
| G
|
Chrnd
|
cholinergic receptor nicotinic delta subunit
|
multiple interactions
|
EXP
|
[Tungsten co-treated with Nickel co-treated with Cobalt] results in decreased expression of CHRND mRNA; [Tungsten co-treated with Nickel co-treated with Iron] results in decreased expression of CHRND mRNA
|
CTD |
PMID:24619124 |
|
NCBI chr 9:95,310,316...95,318,734
Ensembl chr 9:95,310,298...95,318,745
|
|
| G
|
Chst11
|
carbohydrate sulfotransferase 11
|
increases expression
|
ISO
|
Nickel results in increased expression of CHST11 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:22,412,121...22,630,577
Ensembl chr 7:22,415,686...22,630,441
|
|
| G
|
Chst15
|
carbohydrate sulfotransferase 15
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CHST15 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 1:196,458,978...196,540,088
Ensembl chr 1:196,460,425...196,491,444
|
|
| G
|
Chst2
|
carbohydrate sulfotransferase 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CHST2 mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr 8:104,839,716...104,845,961
Ensembl chr 8:104,831,292...104,860,301
|
|
| G
|
Chtf8
|
chromosome transmission fidelity factor 8
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CHTF8 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr19:51,691,776...51,702,076
Ensembl chr19:51,678,543...51,707,144
|
|
| G
|
Cidea
|
cell death-inducing DFFA-like effector a
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CIDEA mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr18:63,164,817...63,190,384
Ensembl chr18:63,164,099...63,190,382
|
|
| G
|
Cidec
|
cell death-inducing DFFA-like effector c
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CIDEC mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:148,124,924...148,137,806
Ensembl chr 4:148,124,925...148,137,806
|
|
| G
|
Ciita
|
class II, major histocompatibility complex, transactivator
|
increases expression
|
ISO
|
Nickel results in increased expression of CIITA mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:5,646,854...5,694,393
Ensembl chr10:5,647,085...5,694,342
|
|
| G
|
Cilp
|
cartilage intermediate layer protein
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CILP mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:74,671,696...74,687,420
Ensembl chr 8:74,671,534...74,687,409
|
|
| G
|
Cir1
|
corepressor interacting with RBPJ, CIR1
|
increases expression
|
ISO
|
Nickel results in increased expression of CIRSR mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 3:78,566,438...78,596,309
Ensembl chr 3:78,566,438...78,596,309
|
|
| G
|
Cisd2
|
CDGSH iron sulfur domain 2
|
increases expression
|
ISO
|
Nickel results in increased expression of CISD2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:226,502,517...226,527,325
Ensembl chr 2:226,502,517...226,540,080
|
|
| G
|
Cish
|
cytokine inducible SH2-containing protein
|
increases expression
|
ISO
|
Nickel results in increased expression of CISH mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:116,850,969...116,855,917
Ensembl chr 8:116,850,773...116,855,986
|
|
| G
|
Cklf
|
chemokine-like factor
|
multiple interactions increases expression
|
ISO
|
[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CKLF mRNA Nickel results in increased expression of CKLF mRNA
|
CTD |
PMID:23503329 PMID:25583101 |
|
NCBI chr19:704,528...712,998
Ensembl chr19:697,451...712,998
|
|
| G
|
Ckm
|
creatine kinase, M-type
|
increases expression
|
ISO
|
Nickel analog results in increased expression of CKM protein
|
CTD |
PMID:25144474 |
|
NCBI chr 1:88,189,382...88,199,717
Ensembl chr 1:88,189,485...88,199,719
|
|
| G
|
Ckmt2
|
creatine kinase, mitochondrial 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CKMT2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:24,815,008...24,845,511
Ensembl chr 2:24,815,008...24,845,511
|
|
| G
|
Cks2
|
CDC28 protein kinase regulatory subunit 2
|
increases expression
|
ISO
|
Nickel results in increased expression of CKS2 mRNA
|
CTD |
PMID:19031421 PMID:25583101 |
|
NCBI chr17:13,722,360...13,727,519
Ensembl chr17:13,722,361...13,727,519
|
|
| G
|
Clca4
|
chloride channel accessory 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CLCA4 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 2:236,543,975...236,565,096
Ensembl chr 2:236,544,201...236,563,435
|
|
| G
|
Clcf1
|
cardiotrophin-like cytokine factor 1
|
increases expression
|
ISO
|
Nickel results in increased expression of CLCF1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:210,937,763...210,947,064
Ensembl chr 1:210,937,255...210,947,064
|
|
| G
|
Clcn4
|
chloride voltage-gated channel 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CLCN4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:27,290,769...27,356,967
Ensembl chr X:27,290,868...27,356,939
|
|
| G
|
Clcn5
|
chloride voltage-gated channel 5
|
increases expression
|
ISO
|
Nickel results in increased expression of CLCN5 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr X:17,857,260...18,011,844
Ensembl chr X:17,857,260...18,011,844
|
|
| G
|
Clcnkb
|
chloride voltage-gated channel Kb
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CLCNKB mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:158,993,073...159,005,618
Ensembl chr 5:158,993,074...159,004,900
|
|
| G
|
Cldn1
|
claudin 1
|
affects response to substance
|
ISO
|
CLDN1 gene SNP affects the susceptibility to Nickel
|
CTD |
PMID:23136956 |
|
NCBI chr11:87,926,376...87,941,533
Ensembl chr11:87,926,337...87,941,529
|
|
| G
|
Cldn10
|
claudin 10
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CLDN10 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr15:102,269,858...102,361,589
Ensembl chr15:102,269,858...102,361,589
|
|
| G
|
Cldn11
|
claudin 11
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CLDN11 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:114,136,234...114,149,539
Ensembl chr 2:114,136,234...114,149,539
|
|
| G
|
Cldn3
|
claudin 3
|
multiple interactions affects expression
|
ISO
|
trichostatin A inhibits the reaction [Nickel affects the expression of CLDN3 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr12:27,345,075...27,346,547
Ensembl chr12:27,345,076...27,348,841
|
|
| G
|
Cldn5
|
claudin 5
|
multiple interactions decreases expression affects expression
|
ISO
|
trichostatin A inhibits the reaction [Nickel affects the expression of CLDN5 mRNA] Nickel results in decreased expression of CLDN5 mRNA
|
CTD |
PMID:14575637 PMID:25583101 |
|
NCBI chr11:95,717,172...95,718,598
Ensembl chr11:95,717,176...95,719,322
|
|
| G
|
Cldn7
|
claudin 7
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CLDN7 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:55,188,670...55,190,871
Ensembl chr10:55,188,684...55,190,905
|
|
| G
|
Cldn8
|
claudin 8
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CLDN8 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:41,362,081...41,364,330
|
|
| G
|
Clec10a
|
C-type lectin domain containing 10A
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of CLEC10A mRNA Nickel results in increased expression of CLEC10A mRNA
|
CTD |
PMID:12540486 PMID:25583101 |
|
NCBI chr10:55,374,914...55,379,110
Ensembl chr10:55,374,887...55,379,108
|
|
| G
|
Clec12b
|
C-type lectin domain family 12, member B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CLEC12B mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 4:164,512,893...164,529,846
Ensembl chr 4:164,513,497...164,524,976
|
|
| G
|
Clec1b
|
C-type lectin domain family 1, member B
|
increases expression
|
ISO
|
Nickel results in increased expression of CLEC1B mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 4:164,533,987...164,542,320
Ensembl chr 4:164,534,055...164,542,867
|
|
| G
|
Clec2d
|
C-type lectin domain family 2, member D
|
increases expression
|
ISO
|
Nickel results in increased expression of CLEC2D mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:163,902,124...163,925,587
Ensembl chr 4:163,902,547...163,925,587
|
|
| G
|
Clec3b
|
C-type lectin domain family 3, member B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CLEC3B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:131,687,575...131,693,292
|
|
| G
|
Clec4a3
|
C-type lectin domain family 4, member A3
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of CLEC4A protein Nickel results in increased expression of CLEC4A mRNA
|
CTD |
PMID:23624239 PMID:25583101 |
|
NCBI chr 4:157,885,899...157,896,728
Ensembl chr 4:157,885,895...157,896,727
|
|
| G
|
Clec4b2
|
C-type lectin domain family 4, member B2
|
increases expression
|
ISO
|
Nickel results in increased expression of CLEC4C mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 4:158,148,434...158,171,933
Ensembl chr 4:158,148,314...158,172,249
|
|
| G
|
Clec4d
|
C-type lectin domain family 4, member D
|
increases expression
|
ISO
|
Nickel results in increased expression of CLEC4D mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:158,275,287...158,286,978
Ensembl chr 4:158,275,341...158,287,055
|
|
| G
|
Clec4e
|
C-type lectin domain family 4, member E
|
increases expression
|
ISO
|
Nickel results in increased expression of CLEC4E mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:158,292,624...158,298,607
Ensembl chr 4:158,293,311...158,298,467
|
|
| G
|
Clec4f
|
C-type lectin domain family 4, member F
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CLEC4F mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:117,686,686...117,696,407
Ensembl chr 4:117,686,686...117,696,438
|
|
| G
|
Clec4g
|
C-type lectin domain family 4, member G
|
increases expression
|
ISO
|
Nickel results in increased expression of CLEC4G mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr12:6,578,266...6,582,913
Ensembl chr12:6,578,258...6,582,894
|
|
| G
|
Clec7a
|
C-type lectin domain containing 7A
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of CLEC7A mRNA Nickel results in increased expression of CLEC7A mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 4:164,588,737...164,599,953
Ensembl chr 4:164,588,754...164,599,919
|
|
| G
|
Clic4
|
chloride intracellular channel 4
|
increases expression
|
ISO
|
Nickel results in increased expression of CLIC4 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 5:152,737,371...152,797,118
Ensembl chr 5:152,737,371...152,797,118
|
|
| G
|
Clic5
|
chloride intracellular channel 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CLIC5 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 9:24,208,455...24,310,964
Ensembl chr 9:24,208,456...24,358,780
|
|
| G
|
Clip1
|
CAP-GLY domain containing linker protein 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CLIP1 mRNA
|
CTD |
PMID:19031421 |
|
NCBI chr12:38,571,533...38,678,779
Ensembl chr12:38,571,834...38,678,779
|
|
| G
|
Clmn
|
calmin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CLMN mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:129,470,613...129,572,079
Ensembl chr 6:129,478,149...129,572,027
|
|
| G
|
Clmp
|
CXADR-like membrane protein
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CLMP mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:49,957,639...50,065,959
Ensembl chr 8:49,957,720...50,065,959
|
|
| G
|
Cln5
|
CLN5, intracellular trafficking protein
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CLN5 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr15:86,308,286...86,321,679
Ensembl chr 2:67,620,667...67,622,952 Ensembl chr15:67,620,667...67,622,952
|
|
| G
|
Clpb
|
ClpB family mitochondrial disaggregase
|
increases expression
|
ISO
|
Nickel results in increased expression of CLPB mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:165,440,705...165,563,514
Ensembl chr 1:165,440,861...165,583,815
|
|
| G
|
Clstn2
|
calsyntenin 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CLSTN2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:106,899,894...107,516,402
Ensembl chr 8:106,899,894...107,040,053
|
|
| G
|
Cltrn
|
collectrin, amino acid transport regulator
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CLTRN mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr X:33,993,825...34,027,124
Ensembl chr X:33,993,825...34,027,181
|
|
| G
|
Clu
|
clusterin
|
multiple interactions decreases expression affects binding affects expression
|
ISO
|
trichostatin A inhibits the reaction [Nickel affects the expression of CLU mRNA] Nickel analog results in decreased expression of CLU protein alternative form CLU protein binds to Nickel
|
CTD |
PMID:14575637 PMID:23896426 PMID:25144474 |
|
NCBI chr15:44,336,619...44,375,861
Ensembl chr15:44,359,914...44,375,860
|
|
| G
|
Clybl
|
citramalyl-CoA lyase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CLYBL mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr15:105,690,283...105,912,347
Ensembl chr15:105,690,295...105,912,345
|
|
| G
|
Cmbl
|
carboxymethylenebutenolidase homolog
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CMBL mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:84,280,128...84,301,878
Ensembl chr 2:84,242,512...84,301,880
|
|
| G
|
Cmklr1
|
chemerin chemokine-like receptor 1
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of CMKLR1 mRNA Nickel results in increased expression of CMKLR1 mRNA
|
CTD |
PMID:23195993 PMID:24768652 |
|
NCBI chr12:48,634,929...48,687,833
Ensembl chr12:48,634,003...48,691,458
|
|
| G
|
Cmpk2
|
cytidine/uridine monophosphate kinase 2
|
increases expression
|
ISO
|
Nickel results in increased expression of CMPK2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 6:48,802,150...48,813,652
Ensembl chr 6:48,802,321...48,813,652
|
|
| G
|
Cmtm7
|
CKLF-like MARVEL transmembrane domain containing 7
|
increases expression
|
ISO
|
Nickel results in increased expression of CMTM7 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:123,326,233...123,353,148
Ensembl chr 8:123,325,975...123,353,148
|
|
| G
|
Cmya5
|
cardiomyopathy associated 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CMYA5 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:26,014,545...26,113,273
Ensembl chr 2:26,014,177...26,113,376
|
|
| G
|
Cnfn
|
cornifelin
|
increases expression
|
ISO
|
Nickel results in increased expression of CNFN mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:90,079,409...90,081,556
Ensembl chr 1:90,078,552...90,081,556
|
|
| G
|
Cnga1
|
cyclic nucleotide gated channel subunit alpha 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CNGA1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:35,920,948...35,959,065
Ensembl chr14:35,926,854...35,959,056
|
|
| G
|
Cnksr2
|
connector enhancer of kinase suppressor of Ras 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CNKSR2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:40,722,843...40,971,730
Ensembl chr X:40,722,996...40,965,604
|
|
| G
|
Cnn1
|
calponin 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CNN1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:28,908,437...28,917,099
Ensembl chr 8:28,908,330...28,919,482
|
|
| G
|
Cnot7
|
CCR4-NOT transcription complex, subunit 7
|
increases expression
|
ISO
|
Nickel results in increased expression of CNOT7 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr16:58,478,882...58,498,046
Ensembl chr16:58,478,900...58,498,046
|
|
| G
|
Cnot9
|
CCR4-NOT transcription complex subunit 9
|
increases expression
|
ISO
|
Nickel results in increased expression of CNOT9 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:83,533,369...83,558,207
Ensembl chr 9:83,533,369...83,558,197
|
|
| G
|
Cntn1
|
contactin 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CNTN1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:125,142,638...125,440,397
Ensembl chr 7:125,142,696...125,440,391
|
|
| G
|
Cntn4
|
contactin 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CNTN4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:140,180,696...141,177,771
Ensembl chr 4:140,596,284...141,177,766
|
|
| G
|
Coa3
|
cytochrome C oxidase assembly factor 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CCDC56 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr10:86,720,454...86,721,435
Ensembl chr10:86,720,456...86,721,440
|
|
| G
|
Cobl
|
cordon-bleu WH2 repeat protein
|
decreases expression
|
ISO
|
Nickel results in decreased expression of COBL mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:91,041,721...91,274,272
Ensembl chr14:91,041,721...91,274,257
|
|
| G
|
Coch
|
cochlin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of COCH mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 6:74,766,485...74,780,504
Ensembl chr 6:74,766,419...74,780,502
|
|
| G
|
Cog2
|
component of oligomeric golgi complex 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of COG2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr19:69,391,305...69,430,072
Ensembl chr19:69,391,326...69,426,620
|
|
| G
|
Cog4
|
component of oligomeric golgi complex 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of COG4 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr19:55,729,854...55,763,902
Ensembl chr19:55,728,796...55,764,169
|
|
| G
|
Col12a1
|
collagen type XII alpha 1 chain
|
increases expression
|
ISO
|
Nickel results in increased expression of COL12A1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 8:89,427,834...89,545,886
Ensembl chr 8:89,427,834...89,545,711
|
|
| G
|
Col14a1
|
collagen type XIV alpha 1 chain
|
decreases expression
|
ISO
|
Nickel results in decreased expression of COL14A1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:88,611,827...88,826,939
Ensembl chr 7:88,611,828...88,826,938
|
|
| G
|
Col16a1
|
collagen type XVI alpha 1 chain
|
decreases expression
|
ISO
|
Nickel results in decreased expression of COL16A1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 5:147,672,559...147,727,007
Ensembl chr 5:147,672,601...147,727,011
|
|
| G
|
Col1a1
|
collagen type I alpha 1 chain
|
increases expression multiple interactions
|
ISO
|
Nickel results in increased expression of COL1A1 mRNA [nickel chloride results in increased abundance of Nickel] which results in increased expression of COL1A1 protein; Acetylcysteine inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of COL1A1 protein] [2-quinoxaline-carboxamide-N-adamantan-1-yl binds to and results in decreased activity of CASR protein] inhibits the reaction [Nickel results in increased expression of COL1A1 mRNA]
|
CTD |
PMID:19781536 PMID:38488660 |
|
NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460
|
|
| G
|
Col1a2
|
collagen type I alpha 2 chain
|
multiple interactions
|
ISO
|
[nickel chloride results in increased abundance of Nickel] which results in increased expression of COL1A2 mRNA
|
CTD |
PMID:38488660 |
|
NCBI chr 4:33,518,557...33,553,484
Ensembl chr 4:33,518,420...33,553,995
|
|
| G
|
Col28a1
|
collagen type XXVIII alpha 1 chain
|
decreases expression
|
ISO
|
Nickel results in decreased expression of COL28A1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:37,036,303...37,189,435
Ensembl chr 4:37,035,761...37,189,494
|
|
| G
|
Col3a1
|
collagen type III alpha 1 chain
|
increases expression
|
ISO
|
Nickel results in increased expression of COL3A1 mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:54,866,632...54,903,232
|
|
| G
|
Col4a1
|
collagen type IV alpha 1 chain
|
increases expression
|
ISO
|
Nickel results in increased expression of COL4A1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr16:84,885,597...84,996,482
Ensembl chr16:84,885,597...84,996,482
|
|
| G
|
Col4a3
|
collagen type IV alpha 3 chain
|
increases expression
|
ISO
|
Nickel results in increased expression of COL4A3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 9:91,323,990...91,453,088
Ensembl chr 9:91,323,990...91,453,077
|
|
| G
|
Col4a4
|
collagen type IV alpha 4 chain
|
increases expression multiple interactions
|
ISO EXP
|
Nickel results in increased expression of COL4A4 mRNA [nickel sulfate results in increased abundance of Nickel] which results in decreased expression of COL4A4 mRNA
|
CTD |
PMID:25583101 PMID:31734292 |
|
NCBI chr 9:91,281,324...91,323,577
Ensembl chr 9:91,203,670...91,323,577
|
|
| G
|
Col4a5
|
collagen type IV alpha 5 chain
|
decreases expression
|
ISO
|
Nickel results in decreased expression of COL4A5 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:109,907,251...110,111,214
Ensembl chr X:109,907,346...110,111,214
|
|
| G
|
Col4a6
|
collagen type IV alpha 6 chain
|
decreases expression
|
ISO
|
Nickel results in decreased expression of COL4A6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:109,554,945...109,905,987
Ensembl chr X:109,552,651...109,905,944
|
|
| G
|
Col6a5
|
collagen type VI alpha 5 chain
|
increases expression
|
ISO
|
Nickel results in increased expression of COL6A5 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:115,362,532...115,462,844
Ensembl chr 8:115,361,906...115,462,859
|
|
| G
|
Col6a6
|
collagen type VI alpha 6 chain
|
increases expression
|
ISO
|
Nickel results in increased expression of COL6A6 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:115,196,833...115,352,161
Ensembl chr 8:115,197,464...115,352,136
|
|
| G
|
Col7a1
|
collagen type VII alpha 1 chain
|
decreases expression
|
ISO
|
Nickel results in decreased expression of COL7A1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 8:118,483,364...118,515,736
Ensembl chr 8:118,483,364...118,517,439
|
|
| G
|
Col8a1
|
collagen type VIII alpha 1 chain
|
decreases expression
|
ISO
|
Nickel results in decreased expression of COL8A1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:56,245,998...56,378,586
Ensembl chr11:56,369,868...56,376,229
|
|
| G
|
Comt
|
catechol-O-methyltransferase
|
decreases expression
|
EXP
|
Nickel results in decreased expression of COMT mRNA
|
CTD |
PMID:18812211 |
|
NCBI chr11:96,072,371...96,091,956
Ensembl chr11:96,072,489...96,092,533
|
|
| G
|
Copb2
|
COPI coat complex subunit beta 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of COPB2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 8:108,040,687...108,062,810
Ensembl chr 8:108,040,693...108,064,550
|
|
| G
|
Copg2
|
COPI coat complex subunit gamma 2
|
multiple interactions
|
ISO
|
MT1 affects the reaction [Nickel affects the expression of COPG2 mRNA]; MT2 affects the reaction [Nickel affects the expression of COPG2 mRNA]
|
CTD |
PMID:16166738 |
|
NCBI chr 4:60,333,455...60,468,953
Ensembl chr 4:60,333,455...60,469,145
|
|
| G
|
Corin
|
corin, serine peptidase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CORIN mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr14:36,034,613...36,264,671
Ensembl chr14:36,034,993...36,264,649
|
|
| G
|
Coro1a
|
coronin 1A
|
increases expression
|
ISO
|
Nickel results in increased expression of CORO1A mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:190,726,129...190,731,133
Ensembl chr 1:190,726,130...190,731,102
|
|
| G
|
Coro2b
|
coronin 2B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CORO2B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:71,802,329...71,912,739
Ensembl chr 8:71,802,329...71,912,739
|
|
| G
|
Cotl1
|
coactosin-like F-actin binding protein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of COTL1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr19:64,780,309...64,814,629
Ensembl chr19:64,780,322...64,814,840
|
|
| G
|
Cox4i2
|
cytochrome c oxidase subunit 4i2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of COX4I2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:161,686,193...161,699,605
Ensembl chr 3:161,689,017...161,699,602
|
|
| G
|
Cox7a1
|
cytochrome c oxidase subunit 7A1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of COX7A1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:94,549,663...94,572,330
Ensembl chr 1:94,569,216...94,570,889
|
|
| G
|
Cp
|
ceruloplasmin
|
affects binding
|
ISO
|
CP protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr 2:104,368,336...104,427,119
Ensembl chr 2:104,368,456...104,427,087
|
|
| G
|
Cpe
|
carboxypeptidase E
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CPE mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr16:29,796,707...29,908,647
Ensembl chr16:29,796,689...29,909,524
|
|
| G
|
Cpeb2
|
cytoplasmic polyadenylation element binding protein 2
|
increases expression
|
ISO
|
Nickel results in increased expression of CPEB2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr14:71,999,958...72,056,012
Ensembl chr14:72,002,072...72,052,263
|
|
| G
|
Cpeb3
|
cytoplasmic polyadenylation element binding protein 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CPEB3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:244,161,690...244,343,765
Ensembl chr 1:244,161,690...244,343,561
|
|
| G
|
Cped1
|
cadherin-like and PC-esterase domain containing 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CPED1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:51,482,497...51,755,440
Ensembl chr 4:51,482,545...51,755,442
|
|
| G
|
Cplane1
|
ciliogenesis and planar polarity effector complex subunit 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CPLANE1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:58,996,119...59,096,817
Ensembl chr 2:58,996,130...59,096,817
|
|
| G
|
Cpn1
|
carboxypeptidase N subunit 1
|
affects binding
|
ISO
|
CPN1 protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr 1:252,793,786...252,822,675
Ensembl chr 1:252,793,423...252,822,664
|
|
| G
|
Cpne4
|
copine 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CPNE4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:114,056,152...114,531,855
Ensembl chr 8:113,993,703...114,531,855
|
|
| G
|
Cpped1
|
calcineurin-like phosphoesterase domain containing 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CPPED1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr10:4,135,601...4,328,039
Ensembl chr10:4,208,463...4,231,065
|
|
| G
|
Cpq
|
carboxypeptidase Q
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CPQ mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 7:66,148,973...66,719,189
Ensembl chr 7:66,149,377...66,716,137
|
|
| G
|
Cpsf2
|
cleavage and polyadenylation specific factor 2
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of CPSF2 mRNA Nickel results in increased expression of CPSF2 mRNA
|
CTD |
PMID:18922574 PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 6:126,885,417...126,917,634
Ensembl chr 6:126,885,476...126,917,632
|
|
| G
|
Cpsf3
|
cleavage and polyadenylation specific factor 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CPSF3 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 6:46,564,855...46,592,776
Ensembl chr 6:46,564,735...46,594,136
|
|
| G
|
Cracr2b
|
calcium release activated channel regulator 2B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CRACR2B mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:205,987,957...205,993,515
Ensembl chr 1:205,990,507...205,993,516
|
|
| G
|
Crat
|
carnitine O-acetyltransferase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CRAT mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 3:34,073,504...34,087,099
Ensembl chr 3:34,073,506...34,087,099
|
|
| G
|
Creb3l4
|
cAMP responsive element binding protein 3-like 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CREB3L4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:177,987,981...177,994,568
Ensembl chr 2:177,987,981...177,993,485
|
|
| G
|
Crebrf
|
CREB3 regulatory factor
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CREBRF mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:16,903,607...16,967,450
Ensembl chr10:16,903,547...16,966,430
|
|
| G
|
Creld2
|
cysteine-rich with EGF-like domains 2
|
increases expression
|
ISO
|
Nickel results in increased expression of CRELD2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:121,788,754...121,796,230
Ensembl chr 7:121,788,745...121,796,228
|
|
| G
|
Crem
|
cAMP responsive element modulator
|
multiple interactions increases expression affects expression
|
ISO
|
trichostatin A inhibits the reaction [Nickel affects the expression of CREM mRNA] Nickel results in increased expression of CREM mRNA
|
CTD |
PMID:14575637 PMID:24768652 |
|
NCBI chr17:58,932,011...59,001,160
Ensembl chr17:58,934,147...59,001,160
|
|
| G
|
Crh
|
corticotropin releasing hormone
|
decreases expression
|
EXP
|
Nickel results in decreased expression of CRH mRNA
|
CTD |
PMID:20682304 |
|
NCBI chr 2:104,059,184...104,061,048
Ensembl chr 2:104,058,770...104,061,386
|
|
| G
|
Crisp3
|
cysteine-rich secretory protein 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CRISP3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:27,928,591...27,969,205
Ensembl chr 9:27,895,536...27,969,198
|
|
| G
|
Crispld1
|
cysteine-rich secretory protein LCCL domain containing 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CRISPLD1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:6,050,970...6,098,265
Ensembl chr 5:6,051,891...6,098,265
|
|
| G
|
Crispld2
|
cysteine-rich secretory protein LCCL domain containing 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CRISPLD2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr19:64,961,764...65,020,099
Ensembl chr19:64,961,771...65,020,349
|
|
| G
|
Crkl
|
CRK like proto-oncogene, adaptor protein
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of CRKL mRNA trichostatin A inhibits the reaction [Nickel affects the expression of CRKL mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr11:97,033,033...97,067,457
Ensembl chr11:97,024,782...97,067,457
|
|
| G
|
Crlf2
|
cytokine receptor-like factor 2
|
increases expression
|
ISO
|
Nickel results in increased expression of CRLF2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr14:118,932...123,632
Ensembl chr14:115,497...123,631
|
|
| G
|
Crp
|
C-reactive protein
|
multiple interactions
|
ISO
|
[nickel chloride results in increased abundance of Nickel] which results in increased expression of CRP mRNA; Resveratrol inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of CRP mRNA]
|
CTD |
PMID:31943712 |
|
NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514
|
|
| G
|
Crtam
|
cytotoxic and regulatory T cell molecule
|
increases expression
|
ISO
|
Nickel results in increased expression of CRTAM mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:50,237,210...50,274,472
Ensembl chr 8:50,237,210...50,274,472
|
|
| G
|
Crtap
|
cartilage associated protein
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CRTAP mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:122,926,117...122,945,843
Ensembl chr 8:122,926,117...122,945,843
|
|
| G
|
Crtc3
|
CREB regulated transcription coactivator 3
|
increases expression
|
ISO
|
Nickel results in increased expression of CRTC3 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 1:143,962,038...144,064,324
Ensembl chr 1:143,962,038...144,064,288
|
|
| G
|
Cry1
|
cryptochrome circadian regulator 1
|
increases expression
|
ISO
|
Nickel results in increased expression of CRY1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 7:20,417,526...20,481,791
Ensembl chr 7:20,417,107...20,481,822
|
|
| G
|
Crym
|
crystallin, mu
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CRYM mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:183,991,752...184,006,923
Ensembl chr 1:183,991,745...184,006,962
|
|
| G
|
Csad
|
cysteine sulfinic acid decarboxylase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CSAD mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:135,187,175...135,216,495
Ensembl chr 7:135,187,175...135,215,581
|
|
| G
|
Csf1
|
colony stimulating factor 1
|
increases expression
|
ISO
|
Nickel results in increased expression of CSF1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:198,065,400...198,084,774
Ensembl chr 2:198,065,405...198,084,468
|
|
| G
|
Csf1r
|
colony stimulating factor 1 receptor
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of CSF1R mRNA Nickel results in increased expression of CSF1R mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr18:56,834,152...56,860,804
Ensembl chr18:56,817,049...56,860,806
|
|
| G
|
Csf2
|
colony stimulating factor 2
|
multiple interactions
|
EXP
|
[Nickel co-treated with Cobalt co-treated with Tungsten] results in increased expression of CSF2 mRNA; [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of CSF2 mRNA
|
CTD |
PMID:22198552 |
|
NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031
|
|
| G
|
Csf2ra
|
colony stimulating factor 2 receptor subunit alpha
|
increases expression
|
ISO
|
Nickel results in increased expression of CSF2RA mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:113,219...118,808
Ensembl chr14:113,225...118,117
|
|
| G
|
Csf2rb
|
colony stimulating factor 2 receptor subunit beta
|
increases expression
|
ISO
|
Nickel results in increased expression of CSF2RB mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:111,756,950...111,782,089
Ensembl chr 7:111,757,405...111,784,654
|
|
| G
|
Csmd1
|
CUB and Sushi multiple domains 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CSMD1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr16:78,920,549...80,520,710
Ensembl chr16:78,921,002...80,519,944
|
|
| G
|
Csn1s1
|
casein alpha s1
|
increases expression
|
ISO
|
Nickel results in increased expression of CSN1S1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr14:20,622,858...20,638,849
|
|
| G
|
Csnk1d
|
casein kinase 1, delta
|
increases expression
|
ISO
|
Nickel results in increased expression of CSNK1D mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:106,713,497...106,754,953
Ensembl chr10:106,694,279...106,754,953
|
|
| G
|
Csrnp2
|
cysteine and serine rich nuclear protein 2
|
increases expression
|
ISO
|
Nickel results in increased expression of CSRNP2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:133,473,027...133,488,868
Ensembl chr 7:133,473,027...133,488,868
|
|
| G
|
Csrnp3
|
cysteine and serine rich nuclear protein 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CSRNP3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:70,906,587...71,102,596
Ensembl chr 3:70,906,380...71,094,009
|
|
| G
|
Cst7
|
cystatin F
|
increases expression
|
ISO
|
Nickel results in increased expression of CST7 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:159,857,221...159,865,987
Ensembl chr 3:159,857,052...159,866,919
|
|
| G
|
Cstb
|
cystatin B
|
increases expression
|
ISO
|
Nickel results in increased expression of CSTB mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr20:10,245,157...10,247,199
Ensembl chr20:10,245,158...10,247,199
|
|
| G
|
Ctbp2
|
C-terminal binding protein 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CTBP2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 1:197,208,536...197,348,802
Ensembl chr 1:197,212,133...197,254,261
|
|
| G
|
Ctdsp2
|
CTD small phosphatase 2
|
increases expression
|
ISO
|
Nickel results in increased expression of CTDSP2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:64,690,737...64,710,639
Ensembl chr 7:64,690,490...64,710,639
|
|
| G
|
Ctdspl
|
CTD small phosphatase like
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CTDSPL mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:127,520,478...127,644,999
Ensembl chr 8:127,520,499...127,644,999
|
|
| G
|
Ctif
|
cap binding complex dependent translation initiation factor
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CTIF mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr18:71,331,222...71,602,493
Ensembl chr18:71,307,314...71,602,492
|
|
| G
|
Ctnnbip1
|
catenin, beta-interacting protein 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CTNNBIP1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 5:165,245,019...165,293,994
Ensembl chr 5:165,245,098...165,293,991
|
|
| G
|
Ctnnd2
|
catenin delta 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CTNND2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:82,879,469...83,727,409
Ensembl chr 2:82,879,469...83,727,409
|
|
| G
|
Ctps1
|
CTP synthase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of CTPS1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:139,372,349...139,440,441
Ensembl chr 5:139,410,249...139,440,465
|
|
| G
|
Ctps2
|
CTP synthase 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CTPS2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:35,277,658...35,418,505
Ensembl chr X:35,277,658...35,418,505
|
|
| G
|
Ctr9
|
CTR9 homolog, Paf1/RNA polymerase II complex component
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CTR9 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 1:174,571,952...174,601,974
Ensembl chr 1:174,571,928...174,602,130
|
|
| G
|
Ctrl
|
chymotrypsin-like
|
increases expression
|
ISO
|
Nickel results in increased expression of CTRL mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr19:50,737,078...50,740,659
Ensembl chr19:50,737,079...50,738,979
|
|
| G
|
Ctsb
|
cathepsin B
|
increases expression
|
ISO
|
Nickel results in increased expression of CTSB mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr15:41,565,607...41,586,479
Ensembl chr15:41,565,611...41,586,478
|
|
| G
|
Ctsc
|
cathepsin C
|
increases expression
|
ISO
|
Nickel results in increased expression of CTSC mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:151,440,860...151,472,430
Ensembl chr 1:151,441,032...151,474,082
|
|
| G
|
Ctsf
|
cathepsin F
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CTSF mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:211,582,169...211,587,917
Ensembl chr 1:211,582,098...211,587,916
|
|
| G
|
Ctsl
|
cathepsin L
|
increases expression
|
ISO
|
Nickel results in increased expression of CTSL mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr17:770,104...776,266
Ensembl chr17:770,093...777,113
|
|
| G
|
Ctss
|
cathepsin S
|
increases expression
|
ISO
|
Nickel results in increased expression of CTSS mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:185,775,316...185,803,440
Ensembl chr 2:185,775,296...185,803,440
|
|
| G
|
Ctsw
|
cathepsin W
|
increases expression
|
ISO
|
Nickel results in increased expression of CTSW mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:212,201,904...212,208,028
Ensembl chr 1:212,201,904...212,205,292
|
|
| G
|
Ctsz
|
cathepsin Z
|
increases expression
|
ISO
|
Nickel results in increased expression of CTSZ mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:183,643,077...183,653,847
Ensembl chr 3:183,643,077...183,657,012
|
|
| G
|
Cttn
|
cortactin
|
increases expression
|
ISO
|
Nickel results in increased expression of CTTN mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 1:209,029,048...209,064,577
Ensembl chr 1:209,029,048...209,058,211
|
|
| G
|
Cttnbp2
|
cortactin binding protein 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CTTNBP2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 4:47,766,867...47,930,598
Ensembl chr 4:47,766,870...47,930,540
|
|
| G
|
Cx3cl1
|
C-X3-C motif chemokine ligand 1
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of CX3CL1 mRNA [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CX3CL1 mRNA; TNF protein promotes the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CX3CL1 mRNA] trichostatin A inhibits the reaction [Nickel affects the expression of CX3CL1 mRNA]
|
CTD |
PMID:14575637 PMID:23503329 |
|
NCBI chr19:10,233,326...10,244,856
Ensembl chr19:10,233,329...10,242,999
|
|
| G
|
Cx3cr1
|
C-X3-C motif chemokine receptor 1
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of CX3CR1 mRNA Nickel results in increased expression of CX3CR1 mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr 8:128,661,294...128,679,048
Ensembl chr 8:128,654,833...128,685,983
|
|
| G
|
Cxcl1
|
C-X-C motif chemokine ligand 1
|
multiple interactions increases expression
|
EXP ISO
|
[Nickel co-treated with Cobalt co-treated with Tungsten] results in increased expression of CXCL1 protein; [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of CXCL1 protein Nickel results in increased expression of CXCL1 mRNA
|
CTD |
PMID:22198552 PMID:25583101 |
|
NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,477,549...17,479,811
|
|
| G
|
Cxcl10
|
C-X-C motif chemokine ligand 10
|
multiple interactions increases expression
|
EXP ISO
|
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [PDGFB protein promotes the reaction [Nickel analog results in increased expression of CXCL10 mRNA]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [PDGFB protein promotes the reaction [Nickel analog results in increased expression of CXCL10 protein]]; PDGFB protein promotes the reaction [Nickel analog results in increased expression of CXCL10 mRNA]; PDGFB protein promotes the reaction [Nickel analog results in increased expression of CXCL10 protein] Nickel results in increased expression of CXCL10 mRNA [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CXCL10 mRNA; [Zinc co-treated with Nickel co-treated with Cobalt] affects the reaction [Dietary Fats affects the expression of CXCL10 mRNA]; TNF protein inhibits the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CXCL10 mRNA] Nickel analog results in increased expression of CXCL10 mRNA; Nickel analog results in increased expression of CXCL10 protein
|
CTD |
PMID:22700867 PMID:23503329 PMID:24768652 PMID:25583101 |
|
NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261
|
|
| G
|
Cxcl11
|
C-X-C motif chemokine ligand 11
|
multiple interactions increases expression
|
ISO
|
[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CXCL11 mRNA Nickel results in increased expression of CXCL11 mRNA
|
CTD |
PMID:23503329 PMID:24768652 PMID:25583101 |
|
NCBI chr14:15,973,728...15,976,503
Ensembl chr14:15,973,720...15,976,567
|
|
| G
|
Cxcl12
|
C-X-C motif chemokine ligand 12
|
decreases expression multiple interactions
|
ISO
|
Nickel results in decreased expression of CXCL12 mRNA [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CXCL12 mRNA; TNF protein inhibits the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CXCL12 mRNA]
|
CTD |
PMID:12540486 PMID:23503329 |
|
NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627
|
|
| G
|
Cxcl16
|
C-X-C motif chemokine ligand 16
|
multiple interactions increases expression
|
ISO
|
[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CXCL16 mRNA; TNF protein promotes the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CXCL16 mRNA] Nickel results in increased expression of CXCL16 mRNA
|
CTD |
PMID:23503329 PMID:25583101 |
|
NCBI chr10:55,665,355...55,669,950
Ensembl chr10:55,664,742...55,670,226
|
|
| G
|
Cxcl17
|
C-X-C motif chemokine ligand 17
|
increases expression
|
ISO
|
Nickel results in increased expression of CXCL17 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:90,112,561...90,124,648
Ensembl chr 1:90,112,771...90,124,535
|
|
| G
|
Cxcl2
|
C-X-C motif chemokine ligand 2
|
multiple interactions increases expression
|
EXP ISO
|
[Nickel co-treated with Cobalt co-treated with Tungsten] results in increased expression of CXCL2 protein; [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of CXCL2 protein Nickel results in increased expression of CXCL2 mRNA Nickel results in increased expression of CXCL2 protein [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CXCL2 mRNA; TNF protein promotes the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CXCL2 mRNA]
|
CTD |
PMID:11919079 PMID:22198552 PMID:23503329 PMID:24768652 PMID:25583101 |
|
NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255
|
|
| G
|
Cxcl3
|
C-X-C motif chemokine ligand 3
|
multiple interactions increases expression
|
ISO
|
[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CXCL1 mRNA; TNF protein inhibits the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CXCL1 mRNA] Nickel results in increased expression of CXCL1 mRNA
|
CTD |
PMID:23503329 PMID:25583101 |
|
NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624
|
|
| G
|
Cxcl6
|
C-X-C motif chemokine ligand 6
|
increases expression
|
ISO
|
Nickel results in increased expression of CXCL6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:17,594,959...17,596,417
Ensembl chr14:17,594,959...17,596,417
|
|
| G
|
Cxcl9
|
C-X-C motif chemokine ligand 9
|
multiple interactions increases expression
|
ISO
|
[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CXCL9 mRNA; TNF protein promotes the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CXCL9 mRNA] Nickel results in increased expression of CXCL9 mRNA
|
CTD |
PMID:23503329 PMID:24768652 PMID:25583101 |
|
NCBI chr14:16,007,166...16,012,077
Ensembl chr14:16,007,204...16,014,299
|
|
| G
|
Cxcr1
|
C-X-C motif chemokine receptor 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CXCR1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 9:83,216,040...83,220,225
Ensembl chr 9:83,215,292...83,226,872
|
|
| G
|
Cxcr2
|
C-X-C motif chemokine receptor 2
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of CXCR2 mRNA Nickel results in increased expression of CXCR2 mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr 9:83,178,645...83,185,017
Ensembl chr 9:83,183,808...83,188,602
|
|
| G
|
Cxcr3
|
C-X-C motif chemokine receptor 3
|
increases expression
|
ISO
|
Nickel results in increased expression of CXCR3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:70,884,293...70,886,944
Ensembl chr X:70,883,958...70,886,871
|
|
| G
|
Cxcr4
|
C-X-C motif chemokine receptor 4
|
increases expression decreases expression
|
ISO
|
Nickel results in increased expression of CXCR4 mRNA Nickel analog results in decreased expression of CXCR4 mRNA
|
CTD |
PMID:24768652 PMID:25144474 PMID:25583101 |
|
NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459
|
|
| G
|
Cxcr6
|
C-X-C motif chemokine receptor 6
|
increases expression
|
ISO
|
Nickel results in increased expression of CXCR6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:132,311,834...132,317,001
Ensembl chr 8:132,306,600...132,322,498
|
|
| G
|
Cxhxorf38
|
similar to human chromosome X open reading frame 38
|
increases expression
|
ISO
|
Nickel results in increased expression of CXORF38 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:12,800,935...12,823,632
Ensembl chr X:12,802,377...12,814,198
|
|
| G
|
Cyb5b
|
cytochrome b5 type B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CYB5B mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr19:51,972,611...52,006,477
Ensembl chr19:51,972,547...52,026,980
|
|
| G
|
Cyb5r4
|
cytochrome b5 reductase 4
|
increases expression
|
ISO
|
Nickel results in increased expression of CYB5R4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:96,860,415...96,925,789
Ensembl chr 8:96,861,090...96,926,094
|
|
| G
|
Cyba
|
cytochrome b-245 alpha chain
|
increases expression
|
ISO
|
Nickel results in increased expression of CYBA mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr19:67,396,143...67,404,214
Ensembl chr19:67,396,143...67,404,214
|
|
| G
|
Cybb
|
cytochrome b-245 beta chain
|
increases expression multiple interactions
|
ISO
|
Nickel results in increased expression of CYBB mRNA [SELENOM protein affects the susceptibility to Nickel] which affects the expression of CYBB mRNA; Melatonin affects the reaction [[SELENOM protein affects the susceptibility to Nickel] which affects the expression of CYBB mRNA]
|
CTD |
PMID:24768652 PMID:25583101 PMID:36504304 |
|
NCBI chr X:16,030,596...16,065,065
Ensembl chr X:16,030,596...16,065,065
|
|
| G
|
Cybc1
|
cytochrome b-245 chaperone 1
|
increases expression
|
ISO
|
Nickel results in increased expression of CYBC1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:106,997,018...107,003,895
Ensembl chr10:106,997,023...107,003,841
|
|
| G
|
Cybrd1
|
cytochrome b reductase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CYBRD1 mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 3:76,342,231...76,369,846
Ensembl chr 3:76,342,404...76,370,061
|
|
| G
|
Cyfip2
|
cytoplasmic FMR1 interacting protein 2
|
increases expression
|
ISO
|
Nickel results in increased expression of CYFIP2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:31,122,653...31,242,440
Ensembl chr10:31,122,653...31,242,440
|
|
| G
|
Cyld
|
CYLD lysine 63 deubiquitinase
|
increases expression
|
ISO
|
Nickel results in increased expression of CYLD mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr19:34,487,491...34,547,311
Ensembl chr19:34,488,583...34,547,118
|
|
| G
|
Cyp1a2
|
cytochrome P450, family 1, subfamily a, polypeptide 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CYP1A2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
|
|
| G
|
Cyp1b1
|
cytochrome P450, family 1, subfamily b, polypeptide 1
|
affects expression multiple interactions increases expression
|
ISO EXP
|
Nickel affects the expression of CYP1B1 mRNA [nickel sulfate results in increased abundance of Nickel] which results in decreased expression of CYP1B1 mRNA Nickel results in increased expression of CYP1B1 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of CYP1B1 mRNA]
|
CTD |
PMID:14575637 PMID:25583101 PMID:31734292 |
|
NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142
|
|
| G
|
Cyp24a1
|
cytochrome P450, family 24, subfamily a, polypeptide 1
|
multiple interactions affects expression
|
ISO
|
trichostatin A inhibits the reaction [Nickel affects the expression of CYP24A1 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 3:179,694,647...179,709,083
Ensembl chr 3:179,694,647...179,709,083
|
|
| G
|
Cyp27a1
|
cytochrome P450, family 27, subfamily a, polypeptide 1
|
decreases expression multiple interactions
|
ISO EXP
|
Nickel results in decreased expression of CYP27A1 mRNA [nickel sulfate results in increased abundance of Nickel] which results in decreased expression of CYP27A1 mRNA
|
CTD |
PMID:25583101 PMID:31734292 |
|
NCBI chr 9:83,712,402...83,743,222
Ensembl chr 9:83,713,293...83,743,215
|
|
| G
|
Cyp27b1
|
cytochrome P450, family 27, subfamily b, polypeptide 1
|
increases expression
|
ISO
|
Nickel results in increased expression of CYP27B1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:64,756,626...64,761,570
Ensembl chr 7:64,756,626...64,761,570
|
|
| G
|
Cyp2a3
|
cytochrome P450, family 2, subfamily a, polypeptide 3
|
multiple interactions decreases expression
|
EXP
|
[Nickel co-treated with Cobalt co-treated with Tungsten] results in decreased expression of CYP2A3 mRNA; [Nickel co-treated with Cobalt co-treated with Tungsten] results in decreased expression of CYP2A3 protein Nickel results in decreased expression of CYP2A3 mRNA
|
CTD |
PMID:22198552 |
|
NCBI chr 1:91,299,584...91,307,650
Ensembl chr 1:91,299,561...91,307,649
|
|
| G
|
Cyp2b3
|
cytochrome P450, family 2, subfamily b, polypeptide 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CYP2B10 mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr 1:90,780,468...90,859,852
|
|
| G
|
Cyp2f4
|
cytochrome P450, family 2, subfamily f, polypeptide 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CYP2F2 mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr 1:91,543,768...91,557,553
Ensembl chr 1:91,543,768...91,557,553
|
|
| G
|
Cyp2u1
|
cytochrome P450, family 2, subfamily u, polypeptide 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CYP2U1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:222,523,516...222,541,055
Ensembl chr 2:222,523,518...222,541,124
|
|
| G
|
Cyp39a1
|
cytochrome P450, family 39, subfamily a, polypeptide 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CYP39A1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:24,727,817...24,804,060
Ensembl chr 9:24,727,817...24,804,060
|
|
| G
|
Cyp3a2
|
cytochrome P450, family 3, subfamily a, polypeptide 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CYP3A4 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
|
|
| G
|
Cyp3a9
|
cytochrome P450, family 3, subfamily a, polypeptide 9
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CYP3A5 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr12:21,919,955...21,960,160
Ensembl chr12:21,919,940...21,960,154
|
|
| G
|
Cyp4a3
|
cytochrome P450, family 4, subfamily a, polypeptide 3
|
multiple interactions
|
EXP
|
[Nickel co-treated with Iron co-treated with Tungsten] results in decreased expression of CYP4A14 mRNA
|
CTD |
PMID:22198552 |
|
NCBI chr 5:134,334,396...134,352,268
Ensembl chr 5:134,334,701...134,352,236
|
|
| G
|
Cyp4f1
|
cytochrome P450, family 4, subfamily f, polypeptide 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CYP4F12 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 7:12,661,357...12,672,952
Ensembl chr 7:12,661,359...12,672,612
|
|
| G
|
Cyp4f6
|
cytochrome P450, family 4, subfamily f, polypeptide 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CYP4F8 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 7:12,680,799...12,708,378
Ensembl chr 7:12,680,806...12,708,402
|
|
| G
|
Cyp7a1
|
cytochrome P450 family 7 subfamily A member 1
|
increases expression
|
ISO
|
Nickel results in increased expression of CYP7A1 mRNA
|
CTD |
PMID:18922574 |
|
NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:24,174,505...24,184,202
|
|
| G
|
Cyp7b1
|
cytochrome P450 family 7 subfamily B member 1
|
increases expression
|
ISO
|
Nickel results in increased expression of CYP7B1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:102,419,011...102,586,047
Ensembl chr 2:102,419,011...102,451,804
|
|
| G
|
Cyria
|
CYFIP related Rac1 interactor A
|
increases expression
|
ISO
|
Nickel results in increased expression of CYRIA mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:40,774,165...40,883,005
Ensembl chr 6:40,774,171...40,881,860
|
|
| G
|
Cyrib
|
CYFIP related Rac1 interactor B
|
increases expression
|
ISO
|
Nickel results in increased expression of CYRIB mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:97,524,941...97,649,846
Ensembl chr 7:97,523,121...97,649,853
|
|
| G
|
Cys1
|
cystin 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CYS1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 6:47,029,440...47,046,671
Ensembl chr 6:47,028,461...47,046,671
|
|
| G
|
Cyth4
|
cytohesin 4
|
increases expression
|
ISO
|
Nickel results in increased expression of CYTH4 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 7:112,032,711...112,057,204
Ensembl chr 7:112,032,775...112,057,204
|
|
| G
|
Cytip
|
cytohesin 1 interacting protein
|
increases expression
|
ISO
|
Nickel results in increased expression of CYTIP mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:63,106,895...63,183,769
Ensembl chr 3:63,107,607...63,134,832
|
|
| G
|
Cytl1
|
cytokine like 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of CYTL1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:77,278,635...77,283,645
Ensembl chr14:77,278,636...77,283,645
|
|
| G
|
Dab2
|
DAB adaptor protein 2
|
increases expression
|
ISO
|
Nickel results in increased expression of DAB2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:57,241,947...57,294,893
Ensembl chr 2:57,242,064...57,294,888
|
|
| G
|
Dach1
|
dachshund family transcription factor 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DACH1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr15:80,936,063...81,317,746
Ensembl chr15:80,936,063...81,317,627
|
|
| G
|
Dact1
|
dishevelled-binding antagonist of beta-catenin 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DACT1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 6:95,526,645...95,538,625
Ensembl chr 6:95,526,690...95,551,053
|
|
| G
|
Dand5
|
DAN domain BMP antagonist family member 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DAND5 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr19:40,231,061...40,245,329
|
|
| G
|
Dapk1
|
death associated protein kinase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DAPK1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr17:3,935,826...4,096,858
Ensembl chr17:3,935,625...4,096,581
|
|
| G
|
Dapl1
|
death associated protein-like 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DAPL1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 3:64,369,734...64,389,677
Ensembl chr 3:64,369,546...64,389,677
|
|
| G
|
Dapp1
|
dual adaptor of phosphotyrosine and 3-phosphoinositides 1
|
increases expression
|
ISO
|
Nickel results in increased expression of DAPP1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:229,099,319...229,148,868
Ensembl chr 2:229,099,319...229,148,843
|
|
| G
|
Dars2
|
aspartyl-tRNA synthetase 2 (mitochondrial)
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DARS2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr13:75,842,078...75,870,319
Ensembl chr13:75,836,565...75,869,904
|
|
| G
|
Dbf4
|
DBF4-CDC7 kinase regulatory subunit
|
increases expression
|
ISO
|
Nickel results in increased expression of DBF4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:26,631,491...26,656,080
Ensembl chr 4:26,631,514...26,656,562
|
|
| G
|
Dbnl
|
drebrin-like
|
increases expression
|
ISO
|
Nickel results in increased expression of DBNL mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:84,880,085...84,895,122
Ensembl chr14:84,880,142...84,897,133
|
|
| G
|
Dbp
|
D-box binding PAR bZIP transcription factor
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DBP mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:105,312,256...105,317,205
Ensembl chr 1:105,312,108...105,317,205
|
|
| G
|
Dbt
|
dihydrolipoamide branched chain transacylase E2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DBT mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:207,166,660...207,195,528
Ensembl chr 2:207,166,652...207,195,525
|
|
| G
|
Dcaf13
|
DDB1 and CUL4 associated factor 13
|
increases expression
|
ISO
|
Nickel results in increased expression of DCAF13 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:72,045,828...72,081,039
Ensembl chr 7:72,045,872...72,083,629
|
|
| G
|
Dcaf7
|
DDB1 and CUL4 associated factor 7
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of DCAF7 mRNA Nickel results in increased expression of DCAF7 mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr10:91,473,900...91,496,080
Ensembl chr10:91,473,900...91,496,080
|
|
| G
|
Dcaf8
|
DDB1 and CUL4 associated factor 8
|
increases expression
|
ISO
|
Nickel results in increased expression of DCAF8 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:87,141,940...87,199,859
Ensembl chr13:87,142,525...87,202,099
|
|
| G
|
Dcbld2
|
discoidin, CUB and LCCL domain containing 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DCBLD2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr11:55,594,691...55,649,113
Ensembl chr11:55,594,691...55,649,085
|
|
| G
|
Dcc
|
DCC netrin 1 receptor
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of DCC mRNA trichostatin A inhibits the reaction [Nickel affects the expression of DCC mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr18:67,144,272...68,248,159
Ensembl chr18:67,149,179...68,247,541
|
|
| G
|
Dclk1
|
doublecortin-like kinase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DCLK1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 2:141,567,215...141,861,088
Ensembl chr 2:141,571,983...141,861,090
|
|
| G
|
Dclre1b
|
DNA cross-link repair 1B
|
increases expression
|
ISO
|
Nickel results in increased expression of DCLRE1B mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:193,998,350...194,006,873
Ensembl chr 2:193,998,354...194,006,864
|
|
| G
|
Dct
|
dopachrome tautomerase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DCT mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr15:101,469,159...101,508,029
Ensembl chr15:101,469,159...101,508,029
|
|
| G
|
Dctn5
|
dynactin subunit 5
|
increases expression
|
ISO
|
Nickel results in increased expression of DCTN5 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:186,120,415...186,137,146
Ensembl chr 1:186,119,913...186,137,146
|
|
| G
|
Dcxr
|
dicarbonyl and L-xylulose reductase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DCXR mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:106,504,730...106,506,619
|
|
| G
|
Ddias
|
DNA damage-induced apoptosis suppressor
|
increases expression
|
ISO
|
Nickel results in increased expression of DDIAS mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:156,318,559...156,342,869
Ensembl chr 1:156,318,563...156,342,869
|
|
| G
|
Ddit3
|
DNA-damage inducible transcript 3
|
multiple interactions increases expression
|
EXP ISO
|
[Nickel co-treated with Cobalt co-treated with Tungsten] results in increased expression of DDIT3 mRNA; [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of DDIT3 mRNA Nickel results in increased expression of DDIT3 mRNA
|
CTD |
PMID:22198552 PMID:23195993 |
|
NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509
|
|
| G
|
Ddit4l
|
DNA-damage-inducible transcript 4-like
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DDIT4L mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:228,800,831...228,804,478
Ensembl chr 2:228,801,705...228,806,225
|
|
| G
|
Ddx17
|
DEAD-box helicase 17
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of DDX17 mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr 7:112,971,522...112,989,747
Ensembl chr 7:112,971,523...112,989,747
|
|
| G
|
Ddx21
|
DExD-box helicase 21
|
increases expression
|
ISO
|
Nickel results in increased expression of DDX21 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr20:31,077,044...31,097,238
Ensembl chr20:31,077,045...31,097,238
|
|
| G
|
Ddx23
|
DEAD-box helicase 23
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DDX23 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 7:131,676,636...131,693,917
Ensembl chr 7:131,676,636...131,689,074
|
|
| G
|
Ddx28
|
DEAD-box helicase 28
|
increases expression
|
ISO
|
Nickel results in increased expression of DDX28 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr19:50,819,643...50,821,573
Ensembl chr19:50,819,313...50,822,803
|
|
| G
|
Ddx39a
|
DExD-box helicase 39A
|
increases expression
|
ISO
|
Nickel results in increased expression of DDX39A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr19:41,323,465...41,331,413
Ensembl chr19:41,322,836...41,332,306
|
|
| G
|
Ddx39b
|
DExD-box helicase 39B
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of DDX39B mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr20:3,577,200...3,589,651
Ensembl chr20:3,576,734...3,589,651
|
|
| G
|
Ddx60
|
DEXD/H-box helicase 60
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of DDX60 mRNA Nickel results in increased expression of DDX60 mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr16:33,087,940...33,208,843
Ensembl chr16:33,087,988...33,208,839
|
|
| G
|
Decr1
|
2,4-dienoyl-CoA reductase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DECR1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 5:34,208,195...34,236,074
Ensembl chr 5:34,208,195...34,236,033
|
|
| G
|
Def6
|
DEF6 guanine nucleotide exchange factor
|
increases expression
|
ISO
|
Nickel results in increased expression of DEF6 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr20:6,270,323...6,291,724
Ensembl chr20:6,269,357...6,291,771
|
|
| G
|
Defb5
|
defensin beta 5
|
increases expression
|
ISO
|
Nickel results in increased expression of DEFB4A mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr16:77,315,424...77,317,828
Ensembl chr16:77,315,424...77,317,828
|
|
| G
|
Dek
|
DEK proto-oncogene
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DEK mRNA
|
CTD |
PMID:18922574 |
|
NCBI chr17:17,786,989...17,809,096
Ensembl chr17:17,787,139...17,810,122
|
|
| G
|
Dennd10
|
DENN domain containing 10
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DENND10 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 1:269,937,023...269,960,506
Ensembl chr 1:269,936,895...269,962,853
|
|
| G
|
Dennd1a
|
DENN domain containing 1A
|
increases expression
|
ISO
|
Nickel results in increased expression of DENND1A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:41,974,502...42,461,816
Ensembl chr 3:41,974,502...42,461,886
|
|
| G
|
Dennd1b
|
DENN domain containing 1B
|
increases expression
|
ISO
|
Nickel results in increased expression of DENND1B mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:53,096,717...53,324,372
Ensembl chr13:53,092,261...53,324,369
|
|
| G
|
Dennd1c
|
DENN domain containing 1C
|
increases expression
|
ISO
|
Nickel results in increased expression of DENND1C mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 9:1,991,035...2,003,330
Ensembl chr 9:1,991,039...2,003,151
|
|
| G
|
Dennd2d
|
DENN domain containing 2D
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of DENND2D mRNA Nickel results in increased expression of DENND2D mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr 2:196,661,465...196,680,505
Ensembl chr 2:196,661,345...196,682,397
|
|
| G
|
Dennd4a
|
DENN domain containing 4A
|
increases expression
|
ISO
|
Nickel results in increased expression of DENND4A mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 8:74,218,131...74,331,543
Ensembl chr 8:74,218,191...74,331,542
|
|
| G
|
Denr
|
density regulated reinitiation and release factor
|
increases expression
|
ISO
|
Nickel results in increased expression of DENR mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr12:38,323,433...38,346,207
Ensembl chr12:38,323,445...38,344,797
|
|
| G
|
Depdc1b
|
DEP domain containing 1B
|
increases expression
|
ISO
|
Nickel results in increased expression of DEPDC1B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:41,605,686...41,697,207
Ensembl chr 2:41,624,922...41,697,202
|
|
| G
|
Deptor
|
DEP domain containing MTOR-interacting protein
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DEPTOR mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:88,404,745...88,574,065
Ensembl chr 7:88,404,620...88,574,041
|
|
| G
|
Des
|
desmin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DES mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:84,299,626...84,307,344
Ensembl chr 9:84,298,447...84,307,347
|
|
| G
|
Dffa
|
DNA fragmentation factor subunit alpha
|
increases expression
|
ISO
|
Nickel results in increased expression of DFFA mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:164,823,807...164,836,729
Ensembl chr 5:164,823,807...164,836,728
|
|
| G
|
Dgat2
|
diacylglycerol O-acyltransferase 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DGAT2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:162,866,237...162,896,655
Ensembl chr 1:162,866,237...162,896,566
|
|
| G
|
Dhcr7
|
7-dehydrocholesterol reductase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DHCR7 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 1:208,444,434...208,460,408
Ensembl chr 1:208,444,434...208,461,382
|
|
| G
|
Dhfr
|
dihydrofolate reductase
|
increases expression
|
ISO
|
Nickel results in increased expression of DHFR mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:25,320,895...25,346,004
|
|
| G
|
Dhrs11
|
dehydrogenase/reductase 11
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DHRS11 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:70,195,637...70,205,735
Ensembl chr10:70,195,637...70,205,893
|
|
| G
|
Dhx32
|
DEAH-box helicase 32 (putative)
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DHX32 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 1:197,954,503...198,013,779
Ensembl chr 1:197,954,503...198,007,489
|
|
| G
|
Dhx58
|
DEXH-box helicase 58
|
increases expression
|
ISO
|
Nickel results in increased expression of DHX58 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr10:86,120,677...86,132,095
Ensembl chr10:86,120,677...86,131,844
|
|
| G
|
Diaph1
|
diaphanous-related formin 1
|
increases expression
|
ISO
|
Nickel results in increased expression of DIAPH1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr18:29,920,889...30,020,280
Ensembl chr18:29,920,889...30,020,280
|
|
| G
|
Dipk1b
|
divergent protein kinase domain 1B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DIPK1B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:29,852,710...29,862,248
Ensembl chr 3:29,853,973...29,862,255
|
|
| G
|
Diras3
|
DIRAS family GTPase 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DIRAS3 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 6:136,346,157...136,347,371
Ensembl chr 6:136,346,154...136,348,376
|
|
| G
|
Disp1
|
dispatched RND transporter family member 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DISP1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:97,252,574...97,398,329
Ensembl chr13:97,252,574...97,398,460
|
|
| G
|
Dixdc1
|
DIX domain containing 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DIXDC1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:59,904,218...59,977,595
Ensembl chr 8:59,904,218...59,978,447
|
|
| G
|
Dkk1
|
dickkopf WNT signaling pathway inhibitor 1
|
decreases expression
|
EXP
|
Nickel results in decreased expression of DKK1 mRNA
|
CTD |
PMID:19130878 |
|
NCBI chr 1:237,794,969...237,798,650
Ensembl chr 1:237,794,969...237,798,650
|
|
| G
|
Dkk2
|
dickkopf WNT signaling pathway inhibitor 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DKK2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:223,242,375...223,334,249
Ensembl chr 2:223,242,377...223,334,724
|
|
| G
|
Dkk3
|
dickkopf WNT signaling pathway inhibitor 3
|
decreases expression
|
EXP ISO
|
Nickel results in decreased expression of DKK3 mRNA
|
CTD |
PMID:19130878 PMID:24768652 PMID:25583101 |
|
NCBI chr 1:175,672,834...175,715,867
Ensembl chr 1:175,672,834...175,715,186
|
|
| G
|
Dlc1
|
DLC1 Rho GTPase activating protein
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DLC1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr16:61,954,177...62,374,819
Ensembl chr16:61,995,001...62,374,819
|
|
| G
|
Dlg2
|
discs large MAGUK scaffold protein 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DLG2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:153,864,545...155,916,238
Ensembl chr 1:153,865,299...155,916,215
|
|
| G
|
Dlx2
|
distal-less homeobox 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DLX2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 3:76,777,912...76,781,255
Ensembl chr 3:76,777,912...76,781,255
|
|
| G
|
Dlx4
|
distal-less homeobox 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DLX4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:80,581,878...80,587,272
Ensembl chr10:80,582,303...80,587,294
|
|
| G
|
Dlx6
|
distal-less homeobox 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DLX6 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:35,951,005...35,956,354
Ensembl chr 4:35,951,005...35,956,354
|
|
| G
|
Dmd
|
dystrophin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DMD mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr X:51,070,098...53,437,845
Ensembl chr X:51,070,273...53,437,835
|
|
| G
|
Dmxl2
|
Dmx-like 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DMXL2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 8:63,637,314...63,803,911
Ensembl chr 8:63,637,314...63,781,116
|
|
| G
|
Dnaaf11
|
dynein axonemal assembly factor 11
|
multiple interactions affects expression
|
ISO
|
trichostatin A inhibits the reaction [Nickel affects the expression of DNAAF11 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 7:100,033,843...100,134,979
Ensembl chr 7:100,034,202...100,135,179
|
|
| G
|
Dnah5
|
dynein, axonemal, heavy chain 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DNAH5 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:80,668,182...80,985,918
Ensembl chr 2:80,668,208...80,985,914
|
|
| G
|
Dnajb1
|
DnaJ heat shock protein family (Hsp40) member B1
|
increases expression
|
ISO
|
Nickel results in increased expression of DNAJB1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr19:41,427,453...41,431,141
Ensembl chr19:41,427,453...41,431,416
|
|
| G
|
Dnajb11
|
DnaJ heat shock protein family (Hsp40) member B11
|
increases expression
|
ISO
|
Nickel results in increased expression of DNAJB11 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:91,656,334...91,672,800
Ensembl chr11:91,656,335...91,672,800
|
|
| G
|
Dnajc18
|
DnaJ heat shock protein family (Hsp40) member C18
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DNAJC18 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr18:27,543,438...27,577,535
Ensembl chr18:27,543,438...27,577,535
|
|
| G
|
Dnase1
|
deoxyribonuclease 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DNASE1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:12,005,305...12,030,615
Ensembl chr10:12,005,306...12,010,497
|
|
| G
|
Dnase1l3
|
deoxyribonuclease 1L3
|
increases expression
|
ISO
|
Nickel results in increased expression of DNASE1L3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr15:19,351,683...19,378,536
Ensembl chr15:19,352,493...19,378,531
|
|
| G
|
Dner
|
delta/notch-like EGF repeat containing
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DNER mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 9:93,035,108...93,350,568
Ensembl chr 9:93,035,108...93,350,568
|
|
| G
|
Dnm1l
|
dynamin 1-like
|
multiple interactions
|
ISO
|
[nickel chloride results in increased abundance of Nickel] which results in increased expression of DNM1L mRNA; [nickel chloride results in increased abundance of Nickel] which results in increased expression of DNM1L protein
|
CTD |
PMID:36794572 |
|
NCBI chr11:98,084,049...98,135,663
Ensembl chr11:98,085,397...98,137,420
|
|
| G
|
Dnmt1
|
DNA methyltransferase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of DNMT1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:27,716,797...27,763,119
|
|
| G
|
Dock10
|
dedicator of cytokinesis 10
|
increases expression
|
ISO
|
Nickel results in increased expression of DOCK10 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:89,291,936...89,549,871
Ensembl chr 9:89,291,800...89,549,973
|
|
| G
|
Dock11
|
dedicator of cytokinesis 11
|
increases expression
|
ISO
|
Nickel results in increased expression of DOCK11 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr X:119,997,523...120,180,643
Ensembl chr X:119,997,552...120,180,634
|
|
| G
|
Dock2
|
dedicator of cytokinesis 2
|
increases expression
|
ISO
|
Nickel results in increased expression of DOCK2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:19,331,412...19,748,987
Ensembl chr10:19,331,412...19,748,969
|
|
| G
|
Dock8
|
dedicator of cytokinesis 8
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of DOCK8 mRNA Nickel results in increased expression of DOCK8 mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 1:232,075,468...232,268,830
Ensembl chr 1:232,075,588...232,268,833
|
|
| G
|
Dock9
|
dedicator of cytokinesis 9
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DOCK9 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr15:105,018,341...105,289,799
Ensembl chr15:105,024,912...105,289,799
|
|
| G
|
Dok2
|
docking protein 2
|
increases expression
|
ISO
|
Nickel results in increased expression of DOK2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr15:52,237,046...52,251,091
Ensembl chr15:52,236,900...52,251,074
|
|
| G
|
Dok3
|
docking protein 3
|
increases expression
|
ISO
|
Nickel results in increased expression of DOK3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr17:9,114,763...9,121,781
Ensembl chr17:9,114,762...9,120,335
|
|
| G
|
Dok5
|
docking protein 5
|
increases expression
|
ISO
|
Nickel results in increased expression of DOK5 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 3:179,934,419...180,071,334
Ensembl chr 3:179,934,552...180,071,333
|
|
| G
|
Dorip1
|
dopamine receptor interacting protein 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DORIP1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:88,701,651...88,710,204
Ensembl chr 6:88,701,818...88,708,820
|
|
| G
|
Dpep2
|
dipeptidase 2
|
increases expression
|
ISO
|
Nickel results in increased expression of DPEP2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr19:50,795,322...50,806,320
Ensembl chr19:50,795,327...50,801,757 Ensembl chr19:50,795,327...50,801,757
|
|
| G
|
Dpf3
|
double PHD fingers 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DPF3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:108,577,792...108,856,724
Ensembl chr 6:108,577,183...108,856,798
|
|
| G
|
Dph2
|
diphthamide biosynthesis 2
|
increases expression
|
ISO
|
Nickel results in increased expression of DPH2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:136,713,868...136,716,828
|
|
| G
|
Dpp3
|
dipeptidylpeptidase 3
|
increases expression
|
ISO
|
Nickel results in increased expression of DPP3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:211,634,067...211,657,898
Ensembl chr 1:211,634,068...211,658,310
|
|
| G
|
Dpp4
|
dipeptidylpeptidase 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DPP4 mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr 3:67,370,794...67,452,422
Ensembl chr 3:67,370,804...67,452,422
|
|
| G
|
Dpp6
|
dipeptidyl peptidase like 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DPP6 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:8,323,220...9,242,694
Ensembl chr 4:8,324,843...9,242,209
|
|
| G
|
Dppa2
|
developmental pluripotency-associated 2
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of DPPA2 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of DPPA2 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr11:66,008,002...66,020,044
Ensembl chr11:66,011,628...66,020,994
|
|
| G
|
Dpt
|
dermatopontin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DPT mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:79,656,341...79,684,759
Ensembl chr13:79,655,985...79,684,758
|
|
| G
|
Dpy19l1
|
dpy-19 like C-mannosyltransferase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of DPY19L1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:31,209,025...31,297,485
Ensembl chr 8:31,209,025...31,297,518
|
|
| G
|
Dpy19l2
|
dpy-19 like 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DPY19L2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:31,338,450...31,457,682
Ensembl chr 8:31,338,488...31,457,725
|
|
| G
|
Dpyd
|
dihydropyrimidine dehydrogenase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DPYD mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 2:209,293,902...210,159,777
Ensembl chr 2:209,293,929...210,159,778
|
|
| G
|
Dpysl3
|
dihydropyrimidinase-like 3
|
increases expression
|
ISO
|
Nickel results in increased expression of DPYSL3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr18:35,625,357...35,731,152
Ensembl chr18:35,625,357...35,731,152
|
|
| G
|
Dqx1
|
DEAQ box RNA-dependent ATPase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DQX1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:117,121,216...117,130,315
Ensembl chr 4:117,121,452...117,130,307
|
|
| G
|
Dsc2
|
desmocollin 2
|
increases expression
|
ISO
|
Nickel results in increased expression of DSC2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr18:11,725,466...11,757,591
Ensembl chr18:11,725,466...11,757,466
|
|
| G
|
Dsel
|
dermatan sulfate epimerase-like
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DSEL mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:194,738...200,959
Ensembl chr13:179,618...200,993
|
|
| G
|
Dsg2
|
desmoglein 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DSG2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr18:12,121,287...12,179,590
Ensembl chr18:12,121,181...12,179,590
|
|
| G
|
Dsg3
|
desmoglein 3
|
increases expression
|
ISO
|
Nickel results in increased expression of DSG3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr18:12,074,321...12,105,954
Ensembl chr18:12,074,321...12,111,766
|
|
| G
|
Dst
|
dystonin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DST mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 9:43,631,716...44,025,535
Ensembl chr 9:43,631,517...44,025,533
|
|
| G
|
Dtl
|
denticleless E3 ubiquitin protein ligase homolog
|
increases expression
|
ISO
|
Nickel results in increased expression of DTL mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:105,646,908...105,685,921
Ensembl chr13:105,646,908...105,686,174
|
|
| G
|
Dtna
|
dystrobrevin, alpha
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DTNA mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr18:14,862,801...15,218,993
Ensembl chr18:14,862,818...15,218,993
|
|
| G
|
Dtwd1
|
DTW domain containing 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DTWD1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:133,845,768...133,859,965
Ensembl chr 3:133,841,935...133,860,316
|
|
| G
|
Dtx3
|
deltex E3 ubiquitin ligase 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DTX3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:64,898,693...64,904,636
Ensembl chr 7:64,898,866...64,903,752
|
|
| G
|
Dtx3l
|
deltex E3 ubiquitin ligase 3L
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of DTX3L mRNA Nickel results in increased expression of DTX3L mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr11:78,320,225...78,329,837
Ensembl chr11:78,317,650...78,329,837
|
|
| G
|
Duox1
|
dual oxidase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of DUOX1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:129,714,125...129,749,186
Ensembl chr 3:129,714,149...129,749,187
|
|
| G
|
Duox2
|
dual oxidase 2
|
increases expression
|
ISO
|
Nickel results in increased expression of DUOX2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:129,680,543...129,698,886
Ensembl chr 3:129,680,546...129,699,203
|
|
| G
|
Duoxa1
|
dual oxidase maturation factor 1
|
increases expression
|
ISO
|
Nickel results in increased expression of DUOXA1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:129,703,416...129,714,110
Ensembl chr 3:129,703,416...129,706,829
|
|
| G
|
Duoxa2
|
dual oxidase maturation factor 2
|
increases expression
|
ISO
|
Nickel results in increased expression of DUOXA2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:129,698,938...129,702,656
Ensembl chr 3:129,698,092...129,702,656
|
|
| G
|
Dusp1
|
dual specificity phosphatase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of DUSP1 mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr10:17,184,853...17,187,646
Ensembl chr10:17,184,823...17,187,644
|
|
| G
|
Dusp10
|
dual specificity phosphatase 10
|
increases expression
|
ISO
|
Nickel results in increased expression of DUSP10 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr13:98,145,317...98,183,304
Ensembl chr13:98,145,893...98,183,304
|
|
| G
|
Dusp3
|
dual specificity phosphatase 3
|
increases expression
|
ISO
|
Nickel results in increased expression of DUSP3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:87,420,213...87,434,202
Ensembl chr10:87,419,494...87,434,063
|
|
| G
|
Dusp5
|
dual specificity phosphatase 5
|
increases expression
|
ISO
|
Nickel results in increased expression of DUSP5 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:262,543,774...262,557,201
Ensembl chr 1:262,543,738...262,562,417
|
|
| G
|
Dusp7
|
dual specificity phosphatase 7
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DUSP7 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 8:115,888,091...115,895,126
Ensembl chr 8:115,887,892...115,895,126
|
|
| G
|
Dusp8
|
dual specificity phosphatase 8
|
increases expression
|
ISO
|
Nickel results in increased expression of DUSP8 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 1:206,596,912...206,613,728
Ensembl chr 1:206,598,942...206,612,441
|
|
| G
|
Dvl1
|
dishevelled segment polarity protein 1
|
decreases expression
|
EXP
|
Nickel results in decreased expression of DVL1 mRNA
|
CTD |
PMID:19130878 |
|
NCBI chr 5:171,738,911...171,750,967
Ensembl chr 5:171,739,133...171,750,966
|
|
| G
|
Dync1i1
|
dynein cytoplasmic 1 intermediate chain 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DYNC1I1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:34,819,313...35,132,647
Ensembl chr 4:34,819,430...35,142,319
|
|
| G
|
Dync1i2
|
dynein cytoplasmic 1 intermediate chain 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DYNC1I2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 3:76,441,621...76,492,782
Ensembl chr 3:76,424,469...76,492,782
|
|
| G
|
Dync2h1
|
dynein cytoplasmic 2 heavy chain 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DYNC2H1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:12,473,955...12,697,075
Ensembl chr 8:12,473,955...12,697,058
|
|
| G
|
Dynlrb2
|
dynein light chain roadblock-type 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DYNLRB2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr19:61,428,782...61,440,331
Ensembl chr19:61,429,065...61,441,071
|
|
| G
|
Dysf
|
dysferlin
|
increases expression
|
ISO
|
Nickel results in increased expression of DYSF mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 4:118,048,460...118,248,273
Ensembl chr 4:118,047,989...118,248,273
|
|
| G
|
Dzip1
|
DAZ interacting zinc finger protein 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of DZIP1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr15:102,363,392...102,417,085
Ensembl chr15:102,363,392...102,417,085
|
|
| G
|
E2f1
|
E2F transcription factor 1
|
multiple interactions
|
EXP
|
[Nickel co-treated with Cobalt co-treated with Tungsten] results in decreased expression of E2F1 mRNA; [Nickel co-treated with Iron co-treated with Tungsten] results in decreased expression of E2F1 mRNA
|
CTD |
PMID:22198552 |
|
NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:163,524,739...163,535,563
|
|
| G
|
E2f3
|
E2F transcription factor 3
|
increases expression
|
ISO
|
Nickel results in increased expression of E2F3 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr17:34,810,355...34,887,725
Ensembl chr17:34,809,998...34,887,725
|
|
| G
|
E2f7
|
E2F transcription factor 7
|
increases expression
|
ISO
|
Nickel results in increased expression of E2F7 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:48,036,881...48,079,055
Ensembl chr 7:48,037,749...48,079,055
|
|
| G
|
Eaf2
|
ELL associated factor 2
|
increases expression
|
ISO
|
Nickel results in increased expression of EAF2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:77,465,585...77,509,993
Ensembl chr11:77,406,020...77,509,993
|
|
| G
|
Ebf1
|
EBF transcription factor 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EBF1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:29,597,221...29,990,571
Ensembl chr10:29,601,351...29,988,702
|
|
| G
|
Ebf2
|
EBF transcription factor 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EBF2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr15:45,610,949...45,809,828
Ensembl chr15:45,610,949...45,809,822
|
|
| G
|
Ebf3
|
EBF transcription factor 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EBF3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:201,426,446...201,544,444
Ensembl chr 1:201,426,450...201,544,305
|
|
| G
|
Ebi3
|
Epstein-Barr virus induced 3
|
increases expression
|
ISO
|
Nickel results in increased expression of EBI3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 9:861,441...874,731
Ensembl chr 9:870,792...874,973
|
|
| G
|
Ebna1bp2
|
EBNA1 binding protein 2
|
increases expression
|
ISO
|
Nickel results in increased expression of EBNA1BP2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:137,433,534...137,438,100
Ensembl chr 5:137,433,226...137,438,637
|
|
| G
|
Ece2
|
endothelin-converting enzyme 2
|
increases expression
|
ISO
|
Nickel results in increased expression of ECE2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr11:93,767,559...93,782,896
Ensembl chr11:93,767,559...93,793,292
|
|
| G
|
Echdc1
|
ethylmalonyl-CoA decarboxylase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ECHDC1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 1:30,304,968...30,355,957
Ensembl chr 1:30,304,971...30,337,208
|
|
| G
|
Echdc2
|
enoyl CoA hydratase domain containing 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ECHDC2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:128,144,241...128,163,611
Ensembl chr 5:128,144,425...128,163,610
|
|
| G
|
Echdc3
|
enoyl CoA hydratase domain containing 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ECHDC3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr17:76,980,112...77,002,934
Ensembl chr17:76,980,083...77,002,934
|
|
| G
|
Eci2
|
enoyl-CoA delta isomerase 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ECI2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr17:30,056,274...30,092,169
Ensembl chr17:30,076,524...30,092,161
|
|
| G
|
Ecm2
|
extracellular matrix protein 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ECM2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr17:15,326,359...15,358,938
Ensembl chr17:15,326,359...15,358,855
|
|
| G
|
Ecrg4
|
ECRG4 augurin precursor
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ECRG4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:53,485,040...53,504,691
Ensembl chr 9:53,485,040...53,504,703
|
|
| G
|
Ect2
|
epithelial cell transforming 2
|
increases expression
|
ISO
|
Nickel results in increased expression of ECT2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:111,904,522...111,966,786
Ensembl chr 2:111,904,522...111,966,626
|
|
| G
|
Eda
|
ectodysplasin-A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EDA mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr X:69,118,577...69,520,274
Ensembl chr X:69,118,796...69,520,274
|
|
| G
|
Edar
|
ectodysplasin-A receptor
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EDAR mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr20:27,130,934...27,209,672
Ensembl chr20:27,130,934...27,209,630
|
|
| G
|
Edem1
|
ER degradation enhancing alpha-mannosidase like protein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of EDEM1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:143,350,989...143,385,693
Ensembl chr 4:143,353,624...143,388,060
|
|
| G
|
Edem3
|
ER degradation enhancing alpha-mannosidase like protein 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EDEM3 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr13:66,403,022...66,470,496
Ensembl chr13:66,408,590...66,472,270
|
|
| G
|
Edil3
|
EGF like repeats and discoidin domains 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EDIL3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:21,625,604...22,140,380
Ensembl chr 2:21,625,596...22,140,379
|
|
| G
|
Edn1
|
endothelin 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EDN1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687
|
|
| G
|
Eea1
|
early endosome antigen 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EEA1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 7:32,441,281...32,608,808
Ensembl chr 7:32,441,272...32,608,476
|
|
| G
|
Eef1akmt2
|
EEF1A lysine methyltransferase 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EEF1AKMT2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:197,009,919...197,071,033
Ensembl chr 1:197,046,930...197,071,013
|
|
| G
|
Eepd1
|
endonuclease/exonuclease/phosphatase family domain containing 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EEPD1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:32,233,834...32,340,148
Ensembl chr 8:32,233,070...32,340,147
|
|
| G
|
Efcab3
|
EF-hand calcium binding domain 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EFCAB3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:90,084,495...90,577,145
Ensembl chr10:90,084,397...90,577,144
|
|
| G
|
Efcc1
|
EF-hand and coiled-coil domain containing 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EFCC1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:121,745,547...121,778,475
Ensembl chr 4:121,745,633...121,775,220
|
|
| G
|
Efhb
|
EF hand domain family, member B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EFHB mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 9:6,608,791...6,680,104
Ensembl chr 9:6,608,794...6,678,827
|
|
| G
|
Efhc1
|
EF-hand domain containing 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EFHC1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:30,872,238...30,910,703
Ensembl chr 9:30,871,565...30,910,703
|
|
| G
|
Efhc2
|
EF-hand domain containing 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EFHC2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:7,943,603...8,144,073
Ensembl chr X:7,943,725...8,144,215
|
|
| G
|
Efhd1
|
EF-hand domain family, member D1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EFHD1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 9:95,386,155...95,432,800
Ensembl chr 9:95,386,169...95,432,798
|
|
| G
|
Efhd2
|
EF-hand domain family, member D2
|
increases expression
|
ISO
|
Nickel results in increased expression of EFHD2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:159,443,959...159,459,993
Ensembl chr 5:159,443,960...159,460,369
|
|
| G
|
Efnb3
|
ephrin B3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EFNB3 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr10:54,773,282...54,780,727
Ensembl chr10:54,773,282...54,797,651
|
|
| G
|
Egf
|
epidermal growth factor
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EGF mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297
|
|
| G
|
Egfl7
|
EGF-like-domain, multiple 7
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EGFL7 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:29,802,481...29,814,966
Ensembl chr 3:29,802,690...29,814,951
|
|
| G
|
Egln2
|
egl-9 family hypoxia-inducible factor 2
|
increases expression
|
ISO
|
Nickel results in increased expression of EGLN2 mRNA
|
CTD |
PMID:20053437 |
|
NCBI chr 1:91,579,205...91,586,985
Ensembl chr 1:91,579,206...91,587,385
|
|
| G
|
Egln3
|
egl-9 family hypoxia-inducible factor 3
|
increases expression
|
ISO
|
Nickel results in increased expression of EGLN3 mRNA
|
CTD |
PMID:18922574 |
|
NCBI chr 6:77,385,549...77,411,015
Ensembl chr 6:77,385,549...77,411,015
|
|
| G
|
Egr1
|
early growth response 1
|
multiple interactions
|
EXP
|
[Tungsten co-treated with Nickel co-treated with Cobalt] results in increased expression of EGR1 mRNA; [Tungsten co-treated with Nickel co-treated with Iron] results in increased expression of EGR1 mRNA
|
CTD |
PMID:24619124 |
|
NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843
|
|
| G
|
Ehbp1
|
EH domain binding protein 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EHBP1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr14:100,294,585...100,581,764
Ensembl chr14:100,294,585...100,546,579
|
|
| G
|
Ehd1
|
EH-domain containing 1
|
increases expression
|
ISO
|
Nickel results in increased expression of EHD1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 1:213,009,113...213,031,488
Ensembl chr 1:213,008,049...213,031,485
|
|
| G
|
Ehd4
|
EH-domain containing 4
|
increases expression
|
ISO
|
Nickel results in increased expression of EHD4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:127,511,973...127,575,856
Ensembl chr 3:127,511,954...127,576,072
|
|
| G
|
Ehmt2
|
euchromatic histone lysine methyltransferase 2
|
multiple interactions
|
ISO
|
Nickel results in decreased expression of and results in decreased activity of EHMT2 protein
|
CTD |
PMID:16648469 |
|
NCBI chr20:3,924,263...3,941,238
Ensembl chr20:3,924,263...3,941,384
|
|
| G
|
Eif1a
|
eukaryotic translation initiation factor 1A
|
increases expression
|
ISO
|
Nickel results in increased expression of EIF1A mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr18:41,512,298...41,524,645
Ensembl chr18:41,503,180...41,549,696
|
|
| G
|
Eif1b
|
eukaryotic translation initiation factor 1B
|
increases expression
|
ISO
|
Nickel results in increased expression of EIF1B mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 8:129,080,497...129,083,772
Ensembl chr 8:129,078,293...129,083,772 Ensembl chr 5:129,078,293...129,083,772
|
|
| G
|
Eif4a1
|
eukaryotic translation initiation factor 4A1
|
increases expression
|
ISO
|
Nickel results in increased expression of EIF4A1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:54,883,093...54,888,602
Ensembl chr10:54,883,093...54,888,602
|
|
| G
|
Eif4a3
|
eukaryotic translation initiation factor 4A3
|
increases expression
|
ISO
|
Nickel results in increased expression of EIF4A3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:105,047,567...105,057,561
Ensembl chr10:105,047,568...105,058,207
|
|
| G
|
Eif4ebp1
|
eukaryotic translation initiation factor 4E binding protein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of EIF4EBP1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr16:71,495,457...71,508,845
Ensembl chr16:71,487,930...71,508,874
|
|
| G
|
Eif4g3
|
eukaryotic translation initiation factor 4 gamma, 3
|
increases expression
|
ISO
|
Nickel results in increased expression of EIF4G3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:155,481,378...155,702,194
Ensembl chr 5:155,481,378...155,702,194
|
|
| G
|
Eif5a
|
eukaryotic translation initiation factor 5A
|
increases expression
|
ISO
|
Nickel results in increased expression of EIF5A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:55,138,821...55,143,272
Ensembl chr10:55,138,823...55,143,330
|
|
| G
|
Elac2
|
elaC ribonuclease Z 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ELAC2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr10:50,131,449...50,154,755
Ensembl chr10:50,131,521...50,155,069
|
|
| G
|
Elapor1
|
endosome-lysosome associated apoptosis and autophagy regulator 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ELAPOR1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:198,777,323...198,856,497
Ensembl chr 2:198,777,323...198,856,497
|
|
| G
|
Elavl1
|
ELAV like RNA binding protein 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ELAVL1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr12:7,441,699...7,482,625
Ensembl chr12:7,441,699...7,482,631
|
|
| G
|
Elf4
|
E74 like ETS transcription factor 4
|
increases expression
|
ISO
|
Nickel results in increased expression of ELF4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:132,465,290...132,508,175
Ensembl chr X:132,468,539...132,478,689
|
|
| G
|
Elf5
|
E74 like ETS transcription factor 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ELF5 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:110,264,460...110,291,926
Ensembl chr 3:110,252,797...110,291,926
|
|
| G
|
Elk4
|
ETS transcription factor ELK4
|
increases expression
|
ISO
|
Nickel results in increased expression of ELK4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:46,004,145...46,027,206
Ensembl chr13:46,004,182...46,027,199
|
|
| G
|
Ell2
|
elongation factor for RNA polymerase II 2
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of ELL2 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of ELL2 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 2:6,910,446...6,990,654
Ensembl chr 2:6,921,771...7,016,199
|
|
| G
|
Eln
|
elastin
|
increases expression decreases expression
|
ISO
|
Nickel results in increased expression of ELN mRNA Nickel results in decreased expression of ELN mRNA
|
CTD |
PMID:12540486 PMID:25583101 |
|
NCBI chr12:27,604,983...27,648,413
Ensembl chr12:27,604,680...27,648,413
|
|
| G
|
Eloa
|
elongin A
|
increases expression
|
ISO
|
Nickel results in increased expression of ELOA mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:153,513,246...153,530,819
Ensembl chr 5:153,515,066...153,530,916
|
|
| G
|
Elovl3
|
ELOVL fatty acid elongase 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ELOVL3 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 1:254,938,731...254,942,559
Ensembl chr 1:254,938,731...254,942,559
|
|
| G
|
Elp3
|
elongator acetyltransferase complex subunit 3
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of ELP3 mRNA Nickel results in increased expression of ELP3 mRNA
|
CTD |
PMID:23195993 PMID:24768652 |
|
NCBI chr15:43,930,234...43,992,065
Ensembl chr15:43,930,234...43,992,214
|
|
| G
|
Elp6
|
elongator acetyltransferase complex subunit 6
|
increases expression
|
ISO
|
Nickel results in increased expression of ELP6 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 8:119,158,380...119,173,483
Ensembl chr 8:119,158,396...119,174,244
|
|
| G
|
Emb
|
embigin
|
increases expression multiple interactions
|
ISO
|
Nickel results in increased expression of EMB mRNA trichostatin A inhibits the reaction [Nickel affects the expression of EMB mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 2:50,803,468...50,858,001
Ensembl chr 2:50,801,973...50,862,920
|
|
| G
|
Emc3
|
ER membrane protein complex subunit 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EMC3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:148,218,686...148,234,595
Ensembl chr 4:148,217,395...148,234,595
|
|
| G
|
Emcn
|
endomucin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EMCN mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:228,564,445...228,644,370
Ensembl chr 2:228,564,430...228,645,155
|
|
| G
|
Eme1
|
essential meiotic structure-specific endonuclease 1
|
increases expression
|
ISO
|
Nickel results in increased expression of EME1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:80,083,585...80,092,450
Ensembl chr10:80,083,585...80,092,301
|
|
| G
|
Emilin2
|
elastin microfibril interfacer 2
|
increases expression
|
ISO
|
Nickel results in increased expression of EMILIN2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:118,607,312...118,667,087
Ensembl chr 9:118,606,891...118,666,957
|
|
| G
|
Emilin3
|
elastin microfibril interfacer 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EMILIN3 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 3:169,978,488...169,984,718
Ensembl chr 3:169,978,672...169,984,488
|
|
| G
|
Eml4
|
EMAP like 4
|
increases expression
|
ISO
|
Nickel results in increased expression of EML4 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 6:16,972,054...17,087,365
Ensembl chr 6:16,972,075...17,087,439
|
|
| G
|
Eml6
|
EMAP like 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EML6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:107,651,893...108,006,792
Ensembl chr14:107,699,400...108,005,409
|
|
| G
|
Emp1
|
epithelial membrane protein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of EMP1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 4:169,931,537...169,964,366
Ensembl chr 4:169,931,440...169,964,365
|
|
| G
|
Emp3
|
epithelial membrane protein 3
|
increases expression
|
ISO
|
Nickel results in increased expression of EMP3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:105,525,086...105,528,370
Ensembl chr 1:105,525,088...105,528,265
|
|
| G
|
Emx2
|
empty spiracles homeobox 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EMX2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:268,612,663...268,619,671
Ensembl chr 1:268,612,663...268,619,671
|
|
| G
|
Emx2os
|
Emx2 opposite strand/antisense RNA
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EMX2OS mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:268,555,719...268,612,889
|
|
| G
|
En1
|
engrailed homeobox 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EN1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:34,303,684...34,309,269
Ensembl chr13:34,303,702...34,309,269
|
|
| G
|
Enkur
|
enkurin, TRPC channel interacting protein
|
increases expression
|
ISO
|
Nickel results in increased expression of ENKUR mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr17:88,599,057...88,622,668
Ensembl chr17:88,599,057...88,622,668
|
|
| G
|
Eno1
|
enolase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of ENO1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:166,002,867...166,014,252
Ensembl chr 3:77,946,261...77,986,003 Ensembl chr 5:77,946,261...77,986,003
|
|
| G
|
Enpp1
|
ectonucleotide pyrophosphatase/phosphodiesterase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ENPP1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:22,518,051...22,583,044
Ensembl chr 1:22,518,069...22,583,044
|
|
| G
|
Enpp5
|
ectonucleotide pyrophosphatase/phosphodiesterase family member 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ENPP5 mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 9:24,407,574...24,415,029
Ensembl chr 9:24,408,218...24,414,867
|
|
| G
|
Entpd1
|
ectonucleoside triphosphate diphosphohydrolase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of ENTPD1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:249,374,810...249,502,310
Ensembl chr 1:249,374,836...249,502,317
|
|
| G
|
Entpd3
|
ectonucleoside triphosphate diphosphohydrolase 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ENTPD3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:129,124,540...129,155,528
Ensembl chr 8:129,124,709...129,156,252
|
|
| G
|
Entpd7
|
ectonucleoside triphosphate diphosphohydrolase 7
|
increases expression
|
ISO
|
Nickel results in increased expression of ENTPD7 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:252,508,594...252,550,269
Ensembl chr 1:252,508,594...252,550,269
|
|
| G
|
Entr1
|
endosome associated trafficking regulator 1
|
increases expression
|
ISO
|
Nickel results in increased expression of ENTR1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:29,599,059...29,605,780
Ensembl chr 3:29,599,059...29,605,898
|
|
| G
|
Entrep1
|
endosomal transmembrane epsin interactor 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ENTREP1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:231,018,987...231,073,474
Ensembl chr 1:231,018,987...231,102,708
|
|
| G
|
Eomes
|
eomesodermin
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of EOMES mRNA Nickel results in increased expression of EOMES mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr 8:127,059,215...127,067,070
Ensembl chr 8:127,059,215...127,067,070
|
|
| G
|
Epas1
|
endothelial PAS domain protein 1
|
multiple interactions
|
ISO
|
EPAS1 protein affects the reaction [Nickel results in increased abundance of Nitric Oxide]
|
CTD |
PMID:23788631 |
|
NCBI chr 6:13,543,252...13,626,147
Ensembl chr 6:13,544,389...13,624,729
|
|
| G
|
Epb41l3
|
erythrocyte membrane protein band 4.1-like 3
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of EPB41L3 mRNA Nickel results in increased expression of EPB41L3 mRNA
|
CTD |
PMID:12540486 PMID:24768652 PMID:25583101 |
|
NCBI chr 9:116,502,864...116,707,274
Ensembl chr 9:116,462,807...116,707,274
|
|
| G
|
Epb41l4b
|
erythrocyte membrane protein band 4.1 like 4B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EPB41L4B mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 5:76,486,886...76,647,752
Ensembl chr 5:76,486,902...76,647,752
|
|
| G
|
Epb41l5
|
erythrocyte membrane protein band 4.1 like 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EPB41L5 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:33,221,705...33,321,400
Ensembl chr13:33,223,589...33,321,133
|
|
| G
|
Epcam
|
epithelial cell adhesion molecule
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EPCAM mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 6:12,633,715...12,649,678
Ensembl chr 6:12,631,611...12,649,702
|
|
| G
|
Epdr1
|
ependymin related 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EPDR1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr17:50,029,591...50,054,254
Ensembl chr17:50,029,256...50,054,250
|
|
| G
|
Epha2
|
Eph receptor A2
|
increases expression
|
ISO
|
Nickel results in increased expression of EPHA2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:158,888,629...158,917,100
Ensembl chr 5:158,888,629...158,917,234
|
|
| G
|
Epha7
|
Eph receptor A7
|
multiple interactions decreases expression affects expression
|
ISO
|
trichostatin A inhibits the reaction [Nickel affects the expression of EPHA7 mRNA] Nickel results in decreased expression of EPHA7 mRNA
|
CTD |
PMID:14575637 PMID:24768652 PMID:25583101 |
|
NCBI chr 5:47,771,776...47,925,189
Ensembl chr 5:47,771,865...47,925,058
|
|
| G
|
Ephb6
|
Eph receptor B6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EPHB6 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 4:71,458,632...71,473,889
Ensembl chr 4:71,458,971...71,476,659
|
|
| G
|
Ephx1
|
epoxide hydrolase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EPHX1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:95,246,079...95,275,852
Ensembl chr13:95,246,080...95,321,981
|
|
| G
|
Ephx2
|
epoxide hydrolase 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EPHX2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr15:44,465,447...44,503,157
Ensembl chr15:44,465,448...44,503,160
|
|
| G
|
Epop
|
elongin BC and polycomb repressive complex 2 associated protein
|
increases expression
|
ISO
|
Nickel results in increased expression of EPOP mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:83,120,767...83,122,287
Ensembl chr10:83,119,970...83,122,423
|
|
| G
|
Epor
|
erythropoietin receptor
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EPOR mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:28,765,738...28,770,371
Ensembl chr 8:28,765,746...28,770,322
|
|
| G
|
Eppk1
|
epiplakin 1
|
increases expression
|
ISO
|
Nickel results in increased expression of EPPK1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:109,697,607...109,718,468
Ensembl chr 7:109,697,607...109,718,468
|
|
| G
|
Eps8l1
|
EPS8 signaling adaptor L1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EPS8L1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 1:78,386,916...78,409,972
Ensembl chr 1:78,386,916...78,406,187
|
|
| G
|
Epsti1
|
epithelial stromal interaction 1
|
increases expression
|
ISO
|
Nickel results in increased expression of EPSTI1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr15:59,692,712...59,791,376
Ensembl chr15:59,693,142...59,791,380
|
|
| G
|
Erbb4
|
erb-b2 receptor tyrosine kinase 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ERBB4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:76,973,386...78,045,633
Ensembl chr 9:76,973,227...78,045,772
|
|
| G
|
Erc1
|
ELKS/RAB6-interacting/CAST family member 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ERC1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:154,435,936...154,727,987
Ensembl chr 4:154,435,944...154,727,987
|
|
| G
|
Ereg
|
epiregulin
|
increases expression
|
ISO
|
Nickel results in increased expression of EREG mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr14:17,311,485...17,325,260
Ensembl chr14:17,311,485...17,325,260
|
|
| G
|
Eri1
|
exoribonuclease 1
|
increases expression
|
ISO
|
Nickel results in increased expression of ERI1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr16:63,427,412...63,447,521
Ensembl chr16:63,427,403...63,447,896
|
|
| G
|
Erlin1
|
ER lipid raft associated 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ERLIN1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 1:252,870,356...252,905,681
Ensembl chr 1:252,870,356...252,905,947
|
|
| G
|
Ermn
|
ermin
|
increases expression
|
ISO
|
Nickel results in increased expression of ERMN mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr 3:63,037,001...63,042,657
Ensembl chr 3:63,035,150...63,042,585
|
|
| G
|
Erp27
|
endoplasmic reticulum protein 27
|
increases expression
|
ISO
|
Nickel results in increased expression of ERP27 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 4:171,535,845...171,552,848
Ensembl chr 4:171,535,847...171,553,072
|
|
| G
|
Esco2
|
establishment of sister chromatid cohesion N-acetyltransferase 2
|
increases expression
|
ISO
|
Nickel results in increased expression of ESCO2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr15:44,210,124...44,230,785
Ensembl chr15:44,210,641...44,231,304 Ensembl chr15:44,210,641...44,231,304
|
|
| G
|
Esd
|
esterase D
|
increases expression
|
ISO
|
Nickel results in increased expression of ESD mRNA
|
CTD |
PMID:18922574 |
|
NCBI chr15:56,453,082...56,472,582
Ensembl chr15:56,453,044...56,473,508
|
|
| G
|
Espl1
|
extra spindle pole bodies like 1, separase
|
increases expression
|
ISO
|
Nickel results in increased expression of ESPL1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:135,302,460...135,329,570
Ensembl chr 7:135,302,716...135,329,570
|
|
| G
|
Esrrg
|
estrogen-related receptor gamma
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ESRRG mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:101,699,043...102,316,877
Ensembl chr13:101,889,706...102,316,877
|
|
| G
|
Esyt1
|
extended synaptotagmin 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ESYT1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 7:1,513,381...1,530,836
Ensembl chr 7:1,513,381...1,530,732
|
|
| G
|
Esyt3
|
extended synaptotagmin 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ESYT3 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 8:108,749,761...108,796,630
Ensembl chr 8:108,750,489...108,796,572
|
|
| G
|
Etfbkmt
|
electron transfer flavoprotein subunit beta lysine methyltransferase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ETFBKMT mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:183,871,819...183,936,843
Ensembl chr 4:183,871,827...183,881,621
|
|
| G
|
Ethe1
|
ETHE1, persulfide dioxygenase
|
increases expression
|
ISO
|
Nickel results in increased expression of ETHE1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:89,311,948...89,327,000
Ensembl chr 1:89,311,934...89,326,998
|
|
| G
|
Etnk1
|
ethanolamine kinase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ETNK1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 4:177,857,001...177,901,278
Ensembl chr 4:177,856,960...177,924,721
|
|
| G
|
Ets1
|
ETS proto-oncogene 1, transcription factor
|
increases expression multiple interactions
|
ISO EXP
|
Nickel results in increased expression of ETS1 mRNA [nickel sulfate results in increased abundance of Nickel] which results in increased expression of ETS1 mRNA
|
CTD |
PMID:25583101 PMID:31734292 |
|
NCBI chr 8:39,303,936...39,426,022
Ensembl chr 8:39,303,925...39,426,021
|
|
| G
|
Ets2
|
ETS proto-oncogene 2, transcription factor
|
increases expression
|
ISO
|
Nickel results in increased expression of ETS2 mRNA
|
CTD |
PMID:21054559 |
|
NCBI chr11:48,491,057...48,507,843
Ensembl chr11:48,491,394...48,507,842
|
|
| G
|
Etv1
|
ETS variant transcription factor 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ETV1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:61,316,836...61,408,985
Ensembl chr 6:61,317,429...61,408,959
|
|
| G
|
Etv6
|
ETS variant transcription factor 6
|
increases expression
|
ISO
|
Nickel results in increased expression of ETV6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:168,580,405...168,819,817
Ensembl chr 4:168,580,138...168,819,802
|
|
| G
|
Evc
|
EvC ciliary complex subunit 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EVC mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:77,680,901...77,722,608
Ensembl chr14:77,680,943...77,723,100
|
|
| G
|
Evi2a
|
ecotropic viral integration site 2A
|
increases expression
|
ISO
|
Nickel results in increased expression of EVI2A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:64,983,727...64,987,627
Ensembl chr10:64,983,705...64,999,516
|
|
| G
|
Evi2b
|
ecotropic viral integration site 2B
|
increases expression
|
ISO
|
Nickel results in increased expression of EVI2B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:64,970,659...64,972,277
Ensembl chr10:64,964,719...64,979,417
|
|
| G
|
Evl
|
Enah/Vasp-like
|
increases expression
|
ISO
|
Nickel results in increased expression of EVL mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:133,238,547...133,358,730
Ensembl chr 6:133,238,547...133,358,729
|
|
| G
|
Exoc1
|
exocyst complex component 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EXOC1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr14:31,965,782...32,014,156
Ensembl chr14:31,965,782...32,014,127
|
|
| G
|
Exog
|
exo/endonuclease G
|
increases expression
|
ISO
|
Nickel results in increased expression of EXOG mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:128,062,688...128,082,529
Ensembl chr 8:128,059,126...128,083,460
|
|
| G
|
Extl3
|
exostosin-like glycosyltransferase 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EXTL3 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr15:43,469,293...43,559,760
Ensembl chr15:43,471,366...43,495,356
|
|
| G
|
Eya2
|
EYA transcriptional coactivator and phosphatase 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EYA2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:174,754,772...174,938,035
Ensembl chr 3:174,818,554...174,938,034
|
|
| G
|
Eya4
|
EYA transcriptional coactivator and phosphatase 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EYA4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:23,991,431...24,235,132
Ensembl chr 1:23,991,431...24,235,131
|
|
| G
|
Ezh1
|
enhancer of zeste 1 polycomb repressive complex 2 subunit
|
decreases expression
|
ISO
|
Nickel results in decreased expression of EZH1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:86,626,307...86,662,257
Ensembl chr10:86,626,308...86,652,620
|
|
| G
|
F10
|
coagulation factor X
|
decreases expression
|
ISO
|
Nickel results in decreased expression of F10 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr16:83,170,973...83,190,280
Ensembl chr16:83,170,977...83,190,280
|
|
| G
|
F12
|
coagulation factor XII
|
affects binding increases expression
|
ISO
|
F12 protein binds to Nickel Nickel results in increased expression of F12 mRNA
|
CTD |
PMID:23896426 PMID:25583101 |
|
NCBI chr17:9,212,819...9,220,664
Ensembl chr17:9,212,819...9,220,664
|
|
| G
|
F2
|
coagulation factor II, thrombin
|
multiple interactions affects binding
|
ISO
|
Nickel inhibits the reaction [F2 protein results in increased uptake of Barium]; Nickel inhibits the reaction [F2 protein results in increased uptake of Calcium]; Nickel inhibits the reaction [F2 protein results in increased uptake of Cobalt]; Nickel inhibits the reaction [F2 protein results in increased uptake of Manganese] F2 protein binds to Nickel
|
CTD |
PMID:2125206 PMID:23896426 |
|
NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:98,051,960...98,065,246
|
|
| G
|
F2rl1
|
F2R like trypsin receptor 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of F2RL1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 2:28,507,003...28,519,954
Ensembl chr 2:28,507,003...28,519,954
|
|
| G
|
F3
|
coagulation factor III, tissue factor
|
increases expression
|
ISO
|
Nickel results in increased expression of F3 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:212,511,680...212,523,369
|
|
| G
|
F5
|
coagulation factor V
|
decreases expression
|
ISO
|
Nickel results in decreased expression of F5 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:79,046,657...79,116,247
Ensembl chr13:79,046,448...79,116,247
|
|
| G
|
Fa2h
|
fatty acid 2-hydroxylase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FA2H mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr19:56,222,240...56,273,480
Ensembl chr19:56,222,242...56,273,623
|
|
| G
|
Fabp7
|
fatty acid binding protein 7
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FABP7 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr20:37,667,125...37,673,299
Ensembl chr20:37,669,601...37,675,907
|
|
| G
|
Fads2
|
fatty acid desaturase 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FADS2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 1:216,132,277...216,172,190
Ensembl chr 1:216,133,676...216,172,066
|
|
| G
|
Fahd1
|
fumarylacetoacetate hydrolase domain containing 1
|
multiple interactions affects expression
|
ISO
|
trichostatin A inhibits the reaction [Nickel affects the expression of FAHD1 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr10:14,378,058...14,379,497
Ensembl chr10:14,378,120...14,379,867
|
|
| G
|
Fahd2a
|
fumarylacetoacetate hydrolase domain containing 2A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FAHD2A mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:135,110,480...135,118,653
Ensembl chr 3:135,109,482...135,118,853
|
|
| G
|
Fam110c
|
family with sequence similarity 110, member C
|
increases expression
|
ISO
|
Nickel results in increased expression of FAM110C mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 6:53,366,013...53,372,270
Ensembl chr 6:53,352,870...53,401,117
|
|
| G
|
Fam118b
|
family with sequence similarity 118, member B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FAM118B mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 8:41,824,522...41,875,190
Ensembl chr 8:41,824,158...41,846,256
|
|
| G
|
Fam13a
|
family with sequence similarity 13, member A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FAM13A mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:89,386,685...89,485,940
Ensembl chr 4:89,388,569...89,485,988
|
|
| G
|
Fam13c
|
family with sequence similarity 13, member C
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FAM13C mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr20:18,064,706...18,186,888
Ensembl chr20:18,064,706...18,286,674
|
|
| G
|
Fam149a
|
family with sequence similarity 149, member A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FAM149A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr16:53,587,841...53,647,072
Ensembl chr16:53,587,841...53,647,072
|
|
| G
|
Fam167a
|
family with sequence similarity 167, member A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FAM167A mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr15:41,861,271...41,891,427
Ensembl chr15:41,861,227...41,891,418
|
|
| G
|
Fam169a
|
family with sequence similarity 169, member A
|
increases expression
|
ISO
|
Nickel results in increased expression of FAM169A mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:30,115,307...30,175,972
Ensembl chr 2:30,119,381...30,175,962
|
|
| G
|
Fam184b
|
family with sequence similarity 184, member B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FAM184B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr14:69,688,031...69,803,922
Ensembl chr14:69,688,031...69,803,922
|
|
| G
|
Fam20a
|
FAM20A, golgi associated secretory pathway pseudokinase
|
increases expression
|
ISO
|
Nickel results in increased expression of FAM20A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:95,136,799...95,197,176
Ensembl chr10:95,142,458...95,197,053
|
|
| G
|
Fam20c
|
FAM20C, golgi associated secretory pathway kinase
|
increases expression
|
ISO
|
Nickel results in increased expression of FAM20C mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr12:20,940,654...20,999,072
Ensembl chr12:20,940,654...20,998,318
|
|
| G
|
Fam210b
|
family with sequence similarity 210, member B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FAM210B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:181,536,665...181,546,830
Ensembl chr 3:181,536,673...181,546,834
|
|
| G
|
Fam219b
|
family with sequence similarity 219, member B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FAM219B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:66,837,230...66,842,819
Ensembl chr 8:66,837,205...66,842,819
|
|
| G
|
Fam228b
|
family with sequence similarity 228, member B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FAM228B mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:33,473,949...33,505,833
Ensembl chr 6:33,473,348...33,505,325
|
|
| G
|
Fam234b
|
family with sequence similarity 234, member B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FAM234B mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:169,779,651...169,854,024
Ensembl chr 4:169,779,737...169,828,678
|
|
| G
|
Fam78a
|
family with sequence similarity 78, member A
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of FAM78A mRNA Nickel results in increased expression of FAM78A mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr 3:35,753,712...35,771,600
Ensembl chr 3:35,753,712...35,770,448
|
|
| G
|
Fam78b
|
family with sequence similarity 78, member B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FAM78B mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr13:81,695,329...81,783,881
Ensembl chr13:81,695,329...81,781,784
|
|
| G
|
Fam83d
|
family with sequence similarity 83, member D
|
increases expression
|
ISO
|
Nickel results in increased expression of FAM83D mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:167,841,748...167,861,062
Ensembl chr 3:167,841,791...167,861,061
|
|
| G
|
Fanca
|
FA complementation group A
|
increases expression
|
ISO
|
Nickel results in increased expression of FANCA mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr19:68,210,562...68,271,080
Ensembl chr19:68,212,643...68,271,019
|
|
| G
|
Far2
|
fatty acyl CoA reductase 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FAR2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 4:182,705,499...182,819,290
Ensembl chr 4:182,705,381...182,825,279
|
|
| G
|
Farp1
|
FERM, ARH/RhoGEF and pleckstrin domain protein 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FARP1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr15:104,531,196...104,770,148
Ensembl chr15:104,531,813...104,770,147
|
|
| G
|
Farsa
|
phenylalanyl-tRNA synthetase subunit alpha
|
increases expression
|
ISO
|
Nickel results in increased expression of FARSA mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr19:40,196,255...40,205,830
Ensembl chr19:40,173,716...40,205,823
|
|
| G
|
Farsb
|
phenylalanyl-tRNA synthetase subunit beta
|
increases expression
|
ISO
|
Nickel results in increased expression of FARSB mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 9:87,336,321...87,395,546
Ensembl chr 9:87,336,326...87,395,505
|
|
| G
|
Fas
|
Fas cell surface death receptor
|
increases expression multiple interactions
|
ISO
|
Nickel results in increased expression of FAS mRNA [Nickel co-treated with austenitic steel analog] results in increased expression of FAS mRNA
|
CTD |
PMID:23638002 PMID:24768652 |
|
NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104
|
|
| G
|
Faslg
|
Fas ligand
|
increases expression
|
ISO
|
Nickel results in increased expression of FASLG mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503
|
|
| G
|
Fasn
|
fatty acid synthase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FASN mRNA
|
CTD |
PMID:12540486 PMID:24768652 |
|
NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583
|
|
| G
|
Fastkd1
|
FAST kinase domains 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FASTKD1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 3:74,857,539...74,883,483
Ensembl chr 3:74,845,261...74,883,367
|
|
| G
|
Fat3
|
FAT atypical cadherin 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FAT3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:20,972,840...21,555,679
Ensembl chr 8:20,972,840...21,555,240
|
|
| G
|
Faxc
|
failed axon connections homolog, metaxin like GST domain containing
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FAXC mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:40,277,167...40,336,503
Ensembl chr 5:40,277,135...40,344,076
|
|
| G
|
Faxdc2
|
fatty acid hydroxylase domain containing 2
|
increases expression decreases expression
|
ISO
|
Nickel results in increased expression of FAXDC2 mRNA Nickel results in decreased expression of FAXDC2 mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr10:42,747,323...42,772,156
Ensembl chr10:42,747,524...42,781,458
|
|
| G
|
Fbn1
|
fibrillin 1
|
increases expression
|
ISO
|
Nickel results in increased expression of FBN1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:133,007,693...133,204,277
Ensembl chr 3:133,008,361...133,204,283
|
|
| G
|
Fbn2
|
fibrillin 2
|
increases expression
|
ISO
|
Nickel results in increased expression of FBN2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr18:53,696,197...53,901,992
Ensembl chr18:53,697,708...53,902,191
|
|
| G
|
Fbxl12
|
F-box and leucine-rich repeat protein 12
|
multiple interactions
|
ISO
|
MT1 affects the reaction [Nickel affects the expression of FBXL12 mRNA]; MT2 affects the reaction [Nickel affects the expression of FBXL12 mRNA]
|
CTD |
PMID:16166738 |
|
NCBI chr 8:27,453,042...27,459,136
Ensembl chr 8:27,445,823...27,457,772
|
|
| G
|
Fbxl13
|
F-box and leucine-rich repeat protein 13
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FBXL13 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:14,307,032...14,505,491
Ensembl chr 4:14,307,096...14,499,585
|
|
| G
|
Fbxo32
|
F-box protein 32
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FBXO32 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 7:91,620,925...91,654,491
Ensembl chr 7:91,620,925...91,654,491
|
|
| G
|
Fbxo38
|
F-box protein 38
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FBXO38 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr18:58,227,253...58,274,320
Ensembl chr18:58,227,262...58,274,262
|
|
| G
|
Fbxo5
|
F-box protein 5
|
increases expression
|
ISO
|
Nickel results in increased expression of FBXO5 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:44,601,412...44,607,781
Ensembl chr 1:44,601,412...44,607,781
|
|
| G
|
Fbxo6
|
F-box protein 6
|
increases expression
|
ISO
|
Nickel results in increased expression of FBXO6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:163,859,909...163,865,693
Ensembl chr 5:163,859,916...163,865,574
|
|
| G
|
Fbxw5
|
F-box and WD repeat domain containing 5
|
multiple interactions
|
EXP
|
[Tungsten co-treated with Nickel co-treated with Cobalt] results in decreased expression of FBXW5 mRNA; [Tungsten co-treated with Nickel co-treated with Iron] results in decreased expression of FBXW5 mRNA
|
CTD |
PMID:24619124 |
|
NCBI chr 3:28,720,670...28,725,237
Ensembl chr 3:28,720,778...28,725,235
|
|
| G
|
Fcer1g
|
Fc epsilon receptor Ig
|
increases expression
|
ISO
|
Nickel results in increased expression of FCER1G mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:86,181,908...86,186,766
Ensembl chr13:86,181,908...86,186,859
|
|
| G
|
Fcgr1a
|
Fc gamma receptor 1A
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of FCGR1A mRNA Nickel results in increased expression of FCGR1A mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 2:186,539,941...186,548,941
Ensembl chr 2:186,539,942...186,548,858
|
|
| G
|
Fcgr2a
|
Fc gamma receptor 2A
|
increases expression decreases expression
|
ISO
|
Nickel results in increased expression of FCGR2A mRNA Nickel results in increased expression of FCGR3 mRNA Nickel results in decreased expression of FCGR2A mRNA
|
CTD |
PMID:12540486 PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr13:85,813,516...85,830,269
Ensembl chr13:85,855,437...85,864,394 Ensembl chr13:85,855,437...85,864,394
|
|
| G
|
Fcgr2b
|
Fc gamma receptor 2B
|
increases expression
|
ISO
|
Nickel results in increased expression of FCGR2B mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:85,725,897...85,740,517
Ensembl chr13:85,725,897...85,740,517
|
|
| G
|
Fcgr3a
|
Fc gamma receptor 3A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FCGR3A mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr13:85,782,636...85,792,656
Ensembl chr13:85,782,490...85,792,651
|
|
| G
|
Fchsd2
|
FCH and double SH3 domains 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FCHSD2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 1:164,775,916...165,097,391
Ensembl chr 1:164,775,926...165,097,391
|
|
| G
|
Fcmr
|
Fc mu receptor
|
increases expression
|
ISO
|
Nickel results in increased expression of FCMR mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr13:44,889,628...44,903,926
Ensembl chr13:44,889,697...44,906,314
|
|
| G
|
Fcnb
|
ficolin B
|
increases expression
|
ISO
|
Nickel results in increased expression of FCN1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:31,791,750...31,800,188
Ensembl chr 3:31,791,750...31,800,188
|
|
| G
|
Fcrla
|
Fc receptor-like A
|
increases expression
|
ISO
|
Nickel results in increased expression of FCRLA mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:85,693,177...85,702,875
Ensembl chr13:85,693,122...85,703,176
|
|
| G
|
Fdcsp
|
follicular dendritic cell secreted protein
|
increases expression
|
ISO
|
Nickel results in increased expression of FDCSP mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr14:20,447,761...20,453,227
Ensembl chr14:20,448,935...20,453,227
|
|
| G
|
Fen1
|
flap structure-specific endonuclease 1
|
increases expression
|
ISO
|
Nickel results in increased expression of FEN1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:216,270,016...216,274,873
Ensembl chr 1:216,269,163...216,275,016
|
|
| G
|
Fermt3
|
FERM domain containing kindlin 3
|
increases expression
|
ISO
|
Nickel results in increased expression of FERMT3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:213,618,691...213,636,889
Ensembl chr 1:213,618,208...213,636,273
|
|
| G
|
Fga
|
fibrinogen alpha chain
|
affects binding
|
ISO
|
FGA protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr 2:170,672,169...170,679,572
Ensembl chr 2:170,672,012...170,679,577
|
|
| G
|
Fgd2
|
FYVE, RhoGEF and PH domain containing 2
|
increases expression
|
ISO
|
Nickel results in increased expression of FGD2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr20:7,426,407...7,443,207
Ensembl chr20:7,426,414...7,443,207
|
|
| G
|
Fgd3
|
FYVE, RhoGEF and PH domain containing 3
|
increases expression
|
ISO
|
Nickel results in increased expression of FGD3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr17:15,531,237...15,593,678
Ensembl chr17:15,543,236...15,593,676
|
|
| G
|
Fgd4
|
FYVE, RhoGEF and PH domain containing 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FGD4 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr11:97,904,182...98,055,190
Ensembl chr11:97,904,182...98,055,190
|
|
| G
|
Fgd5
|
FYVE, RhoGEF and PH domain containing 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FGD5 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:126,054,201...126,151,698
Ensembl chr 4:126,054,210...126,151,697
|
|
| G
|
Fgf1
|
fibroblast growth factor 1
|
decreases expression
|
EXP ISO
|
Nickel results in decreased expression of FGF1 mRNA
|
CTD |
PMID:12540486 PMID:19130878 PMID:24768652 PMID:25583101 |
|
NCBI chr18:30,937,670...31,023,786
Ensembl chr18:30,939,870...30,961,393
|
|
| G
|
Fgf13
|
fibroblast growth factor 13
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FGF13 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr X:142,312,381...142,838,581
Ensembl chr X:142,312,391...142,423,536
|
|
| G
|
Fgf14
|
fibroblast growth factor 14
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FGF14 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr15:107,442,800...108,086,486
Ensembl chr15:107,451,634...108,085,808
|
|
| G
|
Fgf17
|
fibroblast growth factor 17
|
decreases expression
|
EXP
|
Nickel results in decreased expression of FGF17 mRNA
|
CTD |
PMID:19130878 |
|
NCBI chr15:52,118,141...52,132,083
Ensembl chr15:52,121,191...52,132,016
|
|
| G
|
Fgf18
|
fibroblast growth factor 18
|
decreases expression
|
EXP
|
Nickel results in decreased expression of FGF18 mRNA
|
CTD |
PMID:19130878 |
|
NCBI chr10:18,210,240...18,241,929
Ensembl chr10:18,210,512...18,240,933
|
|
| G
|
Fgf19
|
fibroblast growth factor 19
|
affects expression
|
EXP
|
Nickel affects the expression of FGF15 mRNA
|
CTD |
PMID:19130878 |
|
NCBI chr 1:209,485,813...209,490,267
Ensembl chr 1:209,485,813...209,490,267
|
|
| G
|
Fgf2
|
fibroblast growth factor 2
|
decreases expression
|
EXP
|
Nickel results in decreased expression of FGF2 mRNA
|
CTD |
PMID:19130878 |
|
NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493
|
|
| G
|
Fgf21
|
fibroblast growth factor 21
|
affects expression
|
EXP
|
Nickel affects the expression of FGF21 mRNA
|
CTD |
PMID:19130878 |
|
NCBI chr 1:105,219,825...105,221,376
Ensembl chr 1:105,219,825...105,232,056
|
|
| G
|
Fgf22
|
fibroblast growth factor 22
|
affects expression
|
EXP
|
Nickel affects the expression of FGF22 mRNA
|
CTD |
PMID:19130878 |
|
NCBI chr 7:10,598,254...10,600,945
Ensembl chr 7:10,597,538...10,600,945
|
|
| G
|
Fgf7
|
fibroblast growth factor 7
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FGF7 mRNA
|
CTD |
PMID:18922574 |
|
NCBI chr 3:133,734,557...133,786,678
Ensembl chr 3:133,734,673...133,786,328
|
|
| G
|
Fgfbp1
|
fibroblast growth factor binding protein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of FGFBP1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr14:71,316,171...71,319,965
Ensembl chr14:71,317,065...71,320,309
|
|
| G
|
Fgfr2
|
fibroblast growth factor receptor 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FGFR2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:194,175,703...194,280,914
Ensembl chr 1:194,175,705...194,280,914
|
|
| G
|
Fgfr4
|
fibroblast growth factor receptor 4
|
affects expression
|
EXP
|
Nickel affects the expression of FGFR4 mRNA
|
CTD |
PMID:19130878 |
|
NCBI chr17:9,466,686...9,481,423
Ensembl chr17:9,466,692...9,481,389
|
|
| G
|
Fggy
|
FGGY carbohydrate kinase domain containing
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FGGY mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:115,514,573...115,901,713
Ensembl chr 5:115,472,211...115,901,714
|
|
| G
|
Fgl2
|
fibrinogen-like 2
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of FGL2 mRNA Nickel results in increased expression of FGL2 mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr 4:14,602,762...14,608,405
Ensembl chr 4:14,602,771...14,608,405
|
|
| G
|
Fgr
|
FGR proto-oncogene, Src family tyrosine kinase
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of FGR mRNA Nickel results in increased expression of FGR mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr 5:150,473,767...150,503,524
Ensembl chr 5:150,473,792...150,503,169
|
|
| G
|
Fhip1a
|
FHF complex subunit HOOK interacting protein 1A
|
increases expression
|
ISO
|
Nickel results in increased expression of FHIP1A mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:173,319,252...173,489,514
Ensembl chr 2:173,319,257...173,453,902
|
|
| G
|
Fhl1
|
four and a half LIM domains 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FHL1 mRNA
|
CTD |
PMID:12540486 PMID:24768652 PMID:25583101 |
|
NCBI chr X:139,592,794...139,652,290
Ensembl chr X:139,592,604...139,652,282
|
|
| G
|
Fhod3
|
formin homology 2 domain containing 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FHOD3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr18:16,267,830...16,700,508
Ensembl chr18:16,267,977...16,700,508
|
|
| G
|
Fibin
|
fin bud initiation factor homolog
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FIBIN mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:117,396,973...117,399,244
Ensembl chr 3:117,391,724...117,399,479
|
|
| G
|
Fig4
|
FIG4 phosphoinositide 5-phosphatase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FIG4 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr20:46,183,225...46,306,686
Ensembl chr20:46,183,225...46,306,477
|
|
| G
|
Fign
|
fidgetin, microtubule severing factor
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FIGN mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:69,045,918...69,169,148
Ensembl chr 3:69,045,050...69,169,988
|
|
| G
|
Filip1
|
filamin A interacting protein 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FILIP1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:89,641,509...89,836,772
Ensembl chr 8:89,644,579...89,802,771
|
|
| G
|
Fis1
|
fission, mitochondrial 1
|
multiple interactions
|
ISO
|
[nickel chloride results in increased abundance of Nickel] which results in increased expression of FIS1 mRNA; [nickel chloride results in increased abundance of Nickel] which results in increased expression of FIS1 protein
|
CTD |
PMID:36794572 |
|
NCBI chr12:25,345,239...25,360,135
Ensembl chr12:25,345,239...25,349,335
|
|
| G
|
Fitm2
|
fat storage-inducing transmembrane protein 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FITM2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:172,560,781...172,567,291
Ensembl chr 3:172,560,781...172,567,291
|
|
| G
|
Fjx1
|
four-jointed box kinase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of FJX1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:109,229,223...109,231,324
Ensembl chr 3:109,227,170...109,232,479
|
|
| G
|
Fkbp11
|
FKBP prolyl isomerase 11
|
increases expression
|
ISO
|
Nickel results in increased expression of FKBP11 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:131,750,828...131,757,784
Ensembl chr 7:131,750,672...131,770,123
|
|
| G
|
Fkbp15
|
FKBP prolyl isomerase family member 15
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FKBP15 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 5:80,766,356...80,830,622
Ensembl chr 5:80,766,356...80,830,565
|
|
| G
|
Fkbp1a
|
FKBP prolyl isomerase 1A
|
increases expression
|
ISO
|
Nickel results in increased expression of FKBP1A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:160,500,748...160,520,492
Ensembl chr 3:160,500,726...160,524,233
|
|
| G
|
Fkrp
|
fukutin related protein
|
increases expression
|
ISO
|
Nickel results in increased expression of FKRP mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:86,607,769...86,615,045
Ensembl chr 1:86,595,180...86,627,257
|
|
| G
|
Flg
|
filaggrin
|
affects response to substance
|
ISO
|
FLG protein affects the susceptibility to Nickel
|
CTD |
PMID:21166815 |
|
NCBI chr 2:181,583,801...181,596,464
Ensembl chr 2:181,583,808...181,595,968
|
|
| G
|
Flot1
|
flotillin 1
|
increases expression
|
ISO
|
Nickel results in increased expression of FLOT1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr20:2,922,662...2,932,906
Ensembl chr20:2,922,655...2,932,771
|
|
| G
|
Flrt1
|
fibronectin leucine rich transmembrane protein 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FLRT1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:213,704,983...213,782,958
Ensembl chr 1:213,704,038...213,782,981
|
|
| G
|
Flt1
|
Fms related receptor tyrosine kinase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of FLT1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr12:12,333,050...12,504,750
Ensembl chr12:12,333,430...12,504,750
|
|
| G
|
Flt3lg
|
Fms related receptor tyrosine kinase 3 ligand
|
increases expression
|
ISO
|
Nickel results in increased expression of FLT3LG mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:104,751,518...104,756,925
Ensembl chr 1:104,749,983...104,757,038
|
|
| G
|
Flvcr2
|
FLVCR choline and putative heme transporter 2
|
increases expression
|
ISO
|
Nickel results in increased expression of FLVCR2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 6:111,139,352...111,203,345
Ensembl chr 6:111,139,295...111,203,345
|
|
| G
|
Fmnl1
|
formin-like 1
|
increases expression
|
ISO
|
Nickel results in increased expression of FMNL1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:88,615,290...88,643,411
Ensembl chr10:88,615,869...88,643,411
|
|
| G
|
Fmo1
|
flavin containing dimethylaniline monoxygenase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FMO1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:77,715,405...77,747,666
Ensembl chr13:77,715,402...77,747,874
|
|
| G
|
Fmo2
|
flavin containing dimethylaniline monoxygenase 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FMO2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:77,755,131...77,777,597
Ensembl chr13:77,757,629...77,777,534
|
|
| G
|
Fmo4
|
flavin containing dimethylaniline monoxygenase 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FMO4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:77,687,909...77,706,100
Ensembl chr13:77,687,909...77,706,100
|
|
| G
|
Fmo5
|
flavin containing dimethylaniline monoxygenase 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FMO5 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:187,885,741...187,938,468
Ensembl chr 2:187,910,964...187,938,464
|
|
| G
|
Fn1
|
fibronectin 1
|
affects binding
|
ISO
|
FN1 protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137
|
|
| G
|
Fn3k
|
fructosamine 3 kinase
|
multiple interactions
|
EXP
|
[Tungsten co-treated with Nickel co-treated with Cobalt] results in increased expression of FN3K mRNA; [Tungsten co-treated with Nickel co-treated with Iron] results in increased expression of FN3K mRNA
|
CTD |
PMID:24619124 |
|
NCBI chr10:107,198,566...107,214,176
Ensembl chr10:107,198,892...107,214,175
|
|
| G
|
Fnbp1l
|
formin binding protein 1-like
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FNBP1L mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:213,331,871...213,432,821
Ensembl chr 2:213,318,662...213,423,051
|
|
| G
|
Fndc3b
|
fibronectin type III domain containing 3B
|
increases expression
|
ISO
|
Nickel results in increased expression of FNDC3B mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:112,240,108...112,546,113
Ensembl chr 2:112,243,202...112,546,306
|
|
| G
|
Fndc5
|
fibronectin type III domain containing 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FNDC5 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:146,765,951...146,775,611
Ensembl chr 5:146,751,416...146,778,540
|
|
| G
|
Folh1
|
folate hydrolase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FOLH1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:149,828,286...149,914,313
Ensembl chr 1:149,840,760...149,914,035
|
|
| G
|
Folr1
|
folate receptor alpha
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FOLR1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:165,631,462...165,650,430
Ensembl chr 1:165,631,462...165,642,669
|
|
| G
|
Fos
|
Fos proto-oncogene, AP-1 transcription factor subunit
|
increases expression multiple interactions
|
ISO EXP
|
Nickel results in increased expression of FOS mRNA [Tungsten co-treated with Nickel co-treated with Cobalt] results in increased expression of FOS mRNA; [Tungsten co-treated with Nickel co-treated with Iron] results in increased expression of FOS mRNA
|
CTD |
PMID:12540486 PMID:14971665 PMID:24619124 |
|
NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598
|
|
| G
|
Fosb
|
FosB proto-oncogene, AP-1 transcription factor subunit
|
increases expression
|
ISO
|
Nickel results in increased expression of FOSB mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:88,082,127...88,089,477
|
|
| G
|
Fosl1
|
FOS like 1, AP-1 transcription factor subunit
|
increases expression
|
ISO
|
Nickel results in increased expression of FOSL1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:212,183,885...212,192,391
Ensembl chr 1:212,183,833...212,192,391
|
|
| G
|
Fosl2
|
FOS like 2, AP-1 transcription factor subunit
|
increases expression
|
ISO
|
Nickel results in increased expression of FOSL2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:30,017,952...30,039,269
Ensembl chr 6:30,021,916...30,039,406
|
|
| G
|
Foxb1
|
forkhead box B1
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of FOXB1 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of FOXB1 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 8:79,288,161...79,290,781
Ensembl chr 8:79,287,616...79,291,490
|
|
| G
|
Foxc1
|
forkhead box C1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FOXC1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr17:32,840,119...32,844,100
Ensembl chr17:32,805,858...32,844,347
|
|
| G
|
Foxd1
|
forkhead box D1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FOXD1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:31,436,802...31,439,222
Ensembl chr 2:31,436,813...31,439,399
|
|
| G
|
Foxf1
|
forkhead box F1
|
increases expression
|
ISO
|
Nickel results in increased expression of FOXF1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr19:66,062,635...66,066,427
Ensembl chr19:66,062,369...66,066,428
|
|
| G
|
Foxi1
|
forkhead box I1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FOXI1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:19,310,466...19,314,405
Ensembl chr10:19,310,482...19,314,405
|
|
| G
|
Foxo4
|
forkhead box O4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FOXO4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:70,425,218...70,432,120
Ensembl chr X:70,425,563...70,432,120
|
|
| G
|
Foxp2
|
forkhead box P2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FOXP2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:44,099,848...44,677,700
Ensembl chr 4:44,099,959...44,677,696
|
|
| G
|
Foxp3
|
forkhead box P3
|
increases expression
|
ISO
|
Nickel results in increased expression of FOXP3 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr X:17,580,380...17,601,181
Ensembl chr X:17,580,380...17,595,894
|
|
| G
|
Fpgt
|
fucose-1-phosphate guanylyltransferase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FPGT mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 2:246,757,982...246,778,896
Ensembl chr 2:246,757,986...246,778,848
|
|
| G
|
Fpr1
|
formyl peptide receptor 1
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of FPR1 mRNA Nickel results in increased expression of FPR1 mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 1:67,417,991...67,429,813
Ensembl chr 1:67,421,313...67,422,520
|
|
| G
|
Fpr2
|
formyl peptide receptor 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FPR2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 1:67,449,637...67,458,272
Ensembl chr 1:67,449,637...67,458,272
|
|
| G
|
Fpr3
|
formyl peptide receptor 3
|
increases expression
|
ISO
|
Nickel results in increased expression of FPR3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:67,557,464...67,566,509
Ensembl chr 1:67,518,199...67,566,519
|
|
| G
|
Fras1
|
Fraser extracellular matrix complex subunit 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FRAS1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr14:13,095,370...13,506,895
Ensembl chr14:13,095,370...13,504,664
|
|
| G
|
Frem1
|
Fras1 related extracellular matrix 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FREM1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:102,367,201...102,515,464
Ensembl chr 5:102,367,201...102,515,404
|
|
| G
|
Frem2
|
FRAS1 related extracellular matrix 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FREM2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:139,753,055...139,891,046
Ensembl chr 2:139,753,055...139,891,046
|
|
| G
|
Frmd4a
|
FERM domain containing 4A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FRMD4A mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr17:78,577,062...79,167,924
Ensembl chr17:78,579,277...79,167,663
|
|
| G
|
Fry
|
FRY microtubule binding protein
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FRY mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr12:9,530,360...9,773,391
Ensembl chr12:9,530,360...9,897,603
|
|
| G
|
Frzb
|
frizzled-related protein
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FRZB mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:85,739,162...85,772,168
Ensembl chr 3:85,739,165...85,772,096
|
|
| G
|
Fshb
|
follicle stimulating hormone subunit beta
|
decreases expression increases expression
|
EXP
|
Nickel analog results in decreased expression of FSHB protein Nickel analog results in increased expression of FSHB protein
|
CTD |
PMID:25407529 |
|
NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:114,003,262...114,007,072
|
|
| G
|
Ftsj1
|
FtsJ RNA 2'-O-methyltransferase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of FTSJ1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:16,915,087...16,929,426
Ensembl chr X:16,916,033...16,923,999
|
|
| G
|
Ftsj3
|
FtsJ RNA 2'-O-methyltransferase 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FTSJ3 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr10:91,680,735...91,687,475
Ensembl chr10:91,680,753...91,687,179
|
|
| G
|
Fubp1
|
far upstream element binding protein 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FUBP1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 2:243,819,529...243,846,544
Ensembl chr 2:243,819,218...243,846,428
|
|
| G
|
Fuca1
|
alpha-L-fucosidase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FUCA1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 5:153,436,262...153,453,512
Ensembl chr 5:153,436,248...153,453,511
|
|
| G
|
Fundc1
|
FUN14 domain containing 1
|
multiple interactions
|
ISO
|
[nickel chloride results in increased abundance of Nickel] which results in increased expression of FUNDC1 mRNA; [nickel chloride results in increased abundance of Nickel] which results in increased expression of FUNDC1 protein
|
CTD |
PMID:36794572 |
|
NCBI chr X:7,666,787...7,683,443
Ensembl chr X:7,666,759...7,683,441
|
|
| G
|
Fut2
|
fucosyltransferase 2
|
increases expression
|
ISO
|
Nickel results in increased expression of FUT2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:105,256,013...105,276,828
Ensembl chr 1:105,255,390...105,276,647
|
|
| G
|
Fut4
|
fucosyltransferase 4
|
increases expression
|
ISO
|
Nickel results in increased expression of FUT4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:19,868,178...19,872,139
Ensembl chr 8:19,868,079...19,872,436
|
|
| G
|
Fxyd1
|
FXYD domain-containing ion transport regulator 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FXYD1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:95,414,556...95,418,645
Ensembl chr 1:95,414,557...95,418,591
|
|
| G
|
Fxyd3
|
FXYD domain-containing ion transport regulator 3
|
multiple interactions affects expression
|
ISO
|
trichostatin A inhibits the reaction [Nickel affects the expression of FXYD3 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 1:95,432,918...95,440,129
Ensembl chr 1:95,432,919...95,439,702
|
|
| G
|
Fxyd5
|
FXYD domain-containing ion transport regulator 5
|
increases expression
|
ISO
|
Nickel results in increased expression of FXYD5 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:95,395,327...95,404,722
Ensembl chr 1:95,395,146...95,405,364
|
|
| G
|
Fxyd6
|
FXYD domain-containing ion transport regulator 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FXYD6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:54,575,578...54,602,715
Ensembl chr 8:54,575,591...54,602,715
|
|
| G
|
Fyb1
|
FYN binding protein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of FYB1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 2:57,360,084...57,508,609
Ensembl chr 2:57,360,096...57,508,608
|
|
| G
|
Fyn
|
FYN proto-oncogene, Src family tyrosine kinase
|
increases expression
|
ISO
|
Nickel results in increased expression of FYN mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr20:44,322,635...44,514,498
Ensembl chr20:44,322,361...44,515,479
|
|
| G
|
Fzd1
|
frizzled class receptor 1
|
affects expression decreases expression
|
EXP ISO
|
Nickel affects the expression of FZD1 mRNA Nickel results in decreased expression of FZD1 mRNA
|
CTD |
PMID:19130878 PMID:25583101 |
|
NCBI chr 4:30,265,074...30,269,472
Ensembl chr 4:30,247,228...30,833,176
|
|
| G
|
Fzd4
|
frizzled class receptor 4
|
decreases expression multiple interactions affects expression
|
EXP ISO
|
Nickel results in decreased expression of FZD4 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of FZD4 mRNA]
|
CTD |
PMID:14575637 PMID:19130878 PMID:24768652 PMID:25583101 |
|
NCBI chr 1:152,692,507...152,701,372
Ensembl chr 1:152,692,507...152,701,372
|
|
| G
|
Fzd5
|
frizzled class receptor 5
|
increases expression
|
EXP
|
Nickel results in increased expression of FZD5 mRNA
|
CTD |
PMID:19130878 |
|
NCBI chr 9:73,606,860...73,614,039
Ensembl chr 9:73,606,860...73,618,612
|
|
| G
|
Fzd6
|
frizzled class receptor 6
|
decreases expression
|
EXP
|
Nickel results in decreased expression of FZD6 mRNA
|
CTD |
PMID:19130878 |
|
NCBI chr 7:71,939,916...71,971,685
Ensembl chr 7:71,939,973...71,971,680
|
|
| G
|
Fzd8
|
frizzled class receptor 8
|
decreases expression
|
ISO
|
Nickel results in decreased expression of FZD8 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr17:62,007,849...62,015,485
Ensembl chr17:62,007,627...62,015,961
|
|
| G
|
Fzd9
|
frizzled class receptor 9
|
decreases expression
|
EXP
|
Nickel results in decreased expression of FZD9 mRNA
|
CTD |
PMID:19130878 |
|
NCBI chr12:27,063,640...27,065,954
Ensembl chr12:27,063,415...27,074,485
|
|
| G
|
G3bp2
|
G3BP stress granule assembly factor 2
|
increases expression
|
ISO
|
Nickel results in increased expression of G3BP2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:16,216,684...16,304,828
Ensembl chr14:16,248,744...16,304,823
|
|
| G
|
Gabarapl1
|
GABA type A receptor associated protein like 1
|
increases expression
|
ISO
|
Nickel results in increased expression of GABARAPL1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 4:164,666,332...164,675,474
Ensembl chr 4:164,666,246...164,674,578
|
|
| G
|
Gabarapl2
|
GABA type A receptor associated protein like 2
|
multiple interactions
|
ISO
|
MT1 affects the reaction [Nickel affects the expression of GABARAPL2 mRNA]; MT2 affects the reaction [Nickel affects the expression of GABARAPL2 mRNA]
|
CTD |
PMID:16166738 |
|
NCBI chr19:56,819,826...56,830,662
Ensembl chr19:56,819,791...56,830,660
|
|
| G
|
Gabpb1
|
GA binding protein transcription factor subunit beta 1
|
increases expression
|
ISO
|
Nickel results in increased expression of GABPB1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:134,333,339...134,380,239
Ensembl chr 3:134,333,339...134,361,344
|
|
| G
|
Gabrb2
|
gamma-aminobutyric acid type A receptor subunit beta 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GABRB2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:27,438,127...27,657,680
Ensembl chr10:27,438,238...27,655,171
|
|
| G
|
Gabrp
|
gamma-aminobutyric acid type A receptor subunit pi
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GABRP mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:18,647,243...18,673,806
Ensembl chr10:18,647,243...18,673,727
|
|
| G
|
Gadd45b
|
growth arrest and DNA-damage-inducible, beta
|
increases expression
|
ISO
|
Nickel results in increased expression of GADD45B mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 7:9,428,689...9,430,991
Ensembl chr 7:9,428,689...9,430,718
|
|
| G
|
Gal
|
galanin and GMAP prepropeptide
|
decreases expression
|
EXP ISO
|
Nickel results in decreased expression of GAL mRNA
|
CTD |
PMID:20682304 PMID:24768652 |
|
NCBI chr 1:210,079,709...210,084,572
Ensembl chr 1:210,079,702...210,084,229
|
|
| G
|
Gale
|
UDP-galactose-4-epimerase
|
increases expression
|
ISO
|
Nickel results in increased expression of GALE mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 5:153,477,420...153,481,926
Ensembl chr 5:153,478,325...153,481,922
|
|
| G
|
Galm
|
galactose mutarotase
|
increases expression
|
ISO
|
Nickel results in increased expression of GALM mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:20,589,775...20,641,516
Ensembl chr 6:20,589,776...20,644,417
|
|
| G
|
Galnt10
|
polypeptide N-acetylgalactosaminyltransferase 10
|
increases expression
|
ISO
|
Nickel results in increased expression of GALNT10 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr10:42,321,691...42,468,087
Ensembl chr10:42,322,161...42,468,087
|
|
| G
|
Galnt14
|
polypeptide N-acetylgalactosaminyltransferase 14
|
increases expression
|
ISO
|
Nickel results in increased expression of GALNT14 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 6:27,507,878...27,724,033
Ensembl chr 6:27,507,627...27,724,031
|
|
| G
|
Galnt16
|
polypeptide N-acetylgalactosaminyltransferase 16
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GALNT16 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 6:105,900,987...105,982,039
Ensembl chr 6:105,901,153...105,991,350
|
|
| G
|
Galnt2
|
polypeptide N-acetylgalactosaminyltransferase 2
|
multiple interactions increases expression
|
EXP ISO
|
[Tungsten co-treated with Nickel co-treated with Cobalt] results in decreased expression of GALNT2 mRNA Nickel results in increased expression of GALNT2 mRNA
|
CTD |
PMID:24619124 PMID:24768652 PMID:25583101 |
|
NCBI chr19:69,110,657...69,222,237
Ensembl chr19:69,110,657...69,222,237
|
|
| G
|
Galnt6
|
polypeptide N-acetylgalactosaminyltransferase 6
|
increases expression
|
ISO
|
Nickel results in increased expression of GALNT6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:133,668,612...133,715,909
Ensembl chr 7:133,668,615...133,698,439
|
|
| G
|
Gap43
|
growth associated protein 43
|
affects expression
|
EXP
|
Nickel affects the expression of GAP43 mRNA
|
CTD |
PMID:18812211 |
|
NCBI chr11:71,882,131...71,975,799
Ensembl chr11:71,882,131...71,975,797
|
|
| G
|
Gapt
|
Grb2-binding adaptor protein, transmembrane
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GAPT mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 2:43,660,900...43,665,485
Ensembl chr 2:43,660,900...43,665,448
|
|
| G
|
Garnl3
|
GTPase activating Rap/RanGAP domain-like 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GARNL3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:36,686,388...36,830,011
Ensembl chr 3:36,686,389...36,830,020
|
|
| G
|
Gart
|
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of GART mRNA Nickel results in increased expression of GART mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr11:44,351,841...44,377,086
Ensembl chr11:44,351,851...44,377,086
|
|
| G
|
Gas2
|
growth arrest-specific 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GAS2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:110,587,952...110,721,572
Ensembl chr 1:110,717,312...110,718,541
|
|
| G
|
Gask1b
|
golgi associated kinase 1B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GASK1B mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 2:167,345,738...167,410,606
Ensembl chr 2:167,345,809...167,410,603
|
|
| G
|
Gata3
|
GATA binding protein 3
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of GATA3 mRNA Nickel results in increased expression of GATA3 mRNA
|
CTD |
PMID:23195993 PMID:24768652 |
|
NCBI chr17:73,544,234...73,575,670
Ensembl chr17:73,553,548...73,575,670
|
|
| G
|
Gata6
|
GATA binding protein 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GATA6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr18:2,460,909...2,492,322
Ensembl chr18:2,458,253...2,492,322
|
|
| G
|
Gatad1
|
GATA zinc finger domain containing 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GATAD1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:31,462,251...31,473,827
Ensembl chr 4:31,462,309...31,503,921
|
|
| G
|
Gatm
|
glycine amidinotransferase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GATM mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 3:130,112,508...130,137,664
Ensembl chr 3:130,112,509...130,129,355
|
|
| G
|
Gba2
|
glucosylceramidase beta 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GBA2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 5:62,618,176...62,630,160
Ensembl chr 5:62,618,177...62,630,308
|
|
| G
|
Gbp1
|
guanylate binding protein 1
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of GBP1 mRNA Nickel results in increased expression of GBP1 mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 2:234,071,366...234,106,012
Ensembl chr 2:234,190,708...234,206,802 Ensembl chr 2:234,190,708...234,206,802
|
|
| G
|
Gbp2
|
guanylate binding protein 2
|
increases expression
|
ISO
|
Nickel results in increased expression of GBP2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 2:234,005,727...234,021,812
Ensembl chr 2:234,008,590...234,021,810
|
|
| G
|
Gbp3
|
guanylate binding protein 3
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of GBP3 mRNA Nickel results in increased expression of GBP3 mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr 2:234,144,042...234,173,527
Ensembl chr 2:234,146,519...234,180,055
|
|
| G
|
Gbp4
|
guanylate binding protein 4
|
increases expression decreases expression
|
ISO
|
Nickel results in increased expression of GBP4 mRNA Nickel results in decreased expression of GBP4 mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 2:233,978,163...233,992,124
Ensembl chr 2:233,978,486...233,992,120
|
|
| G
|
Gbp5
|
guanylate binding protein 5
|
increases expression
|
ISO
|
Nickel results in increased expression of GBP5 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:233,910,999...233,930,320
Ensembl chr 2:233,902,113...233,930,826
|
|
| G
|
Gc
|
GC, vitamin D binding protein
|
affects binding
|
ISO
|
GC protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr14:18,916,255...18,951,670
Ensembl chr14:18,916,246...18,951,673
|
|
| G
|
Gca
|
grancalcin
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of GCA mRNA Nickel results in increased expression of GCA mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 3:67,705,874...67,738,475
Ensembl chr 3:67,705,890...67,737,387
|
|
| G
|
Gch1
|
GTP cyclohydrolase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of GCH1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr15:22,884,006...22,917,412
Ensembl chr15:22,884,006...22,917,412
|
|
| G
|
Gchfr
|
GTP cyclohydrolase I feedback regulator
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GCHFR mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:126,611,892...126,615,926
Ensembl chr 3:126,613,240...126,615,926
|
|
| G
|
Gclm
|
glutamate cysteine ligase, modifier subunit
|
increases expression
|
ISO
|
Nickel results in increased expression of GCLM mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003
|
|
| G
|
Gcnt1
|
glucosaminyl (N-acetyl) transferase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of GCNT1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:224,145,104...224,182,496
Ensembl chr 1:224,141,108...224,185,741
|
|
| G
|
Gdf10
|
growth differentiation factor 10
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GDF10 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr16:9,243,434...9,256,788
Ensembl chr16:9,243,317...9,256,794
|
|
| G
|
Gdpd1
|
glycerophosphodiester phosphodiesterase domain containing 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GDPD1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:72,318,716...72,381,143
Ensembl chr10:72,337,778...72,381,120
|
|
| G
|
Gem
|
GTP binding protein overexpressed in skeletal muscle
|
multiple interactions affects expression
|
ISO
|
trichostatin A inhibits the reaction [Nickel affects the expression of GEM mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 5:30,011,641...30,022,554
Ensembl chr 5:30,011,592...30,022,542
|
|
| G
|
Gemin5
|
gem (nuclear organelle) associated protein 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GEMIN5 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr10:42,797,975...42,843,356
Ensembl chr10:42,797,982...42,843,356
|
|
| G
|
Gfi1
|
growth factor independent 1 transcriptional repressor
|
increases expression
|
ISO
|
Nickel results in increased expression of GFI1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:2,185,489...2,204,191
Ensembl chr14:2,187,286...2,196,730
|
|
| G
|
Gfpt1
|
glutamine fructose-6-phosphate transaminase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of GFPT1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:121,054,023...121,103,799
Ensembl chr 4:121,054,045...121,103,799
|
|
| G
|
Gfpt2
|
glutamine-fructose-6-phosphate transaminase 2
|
increases expression
|
ISO
|
Nickel results in increased expression of GFPT2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:34,616,146...34,662,420
Ensembl chr10:34,615,370...34,662,419
|
|
| G
|
Gfra1
|
GDNF family receptor alpha 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GFRA1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:267,325,297...267,557,037
Ensembl chr 1:267,326,817...267,556,501
|
|
| G
|
Gfra3
|
GDNF family receptor alpha 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GFRA3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr18:26,571,952...26,600,225
Ensembl chr18:26,571,921...26,600,225
|
|
| G
|
Gfus
|
GDP-L-fucose synthase
|
increases expression
|
ISO
|
Nickel results in increased expression of GFUS mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:109,492,808...109,497,719
Ensembl chr 7:109,492,809...109,497,662
|
|
| G
|
Ggt1
|
gamma-glutamyltransferase 1
|
multiple interactions
|
EXP
|
[Zinc co-treated with Copper co-treated with Manganese co-treated with Potassium Dichromate co-treated with Nickel co-treated with Cadmium co-treated with Lead co-treated with Mercury] affects the expression of GGT1 protein
|
CTD |
PMID:30090589 |
|
NCBI chr20:13,074,141...13,103,551
Ensembl chr20:13,074,141...13,088,050
|
|
| G
|
Ghr
|
growth hormone receptor
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GHR mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:54,269,066...54,532,595
Ensembl chr 2:54,270,206...54,532,331
|
|
| G
|
Gimap1
|
GTPase, IMAP family member 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GIMAP1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 4:79,018,473...79,022,360
Ensembl chr 4:79,018,202...79,022,525
|
|
| G
|
Gimap4
|
GTPase, IMAP family member 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GIMAP4 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 4:78,967,297...78,974,211
Ensembl chr 4:78,967,297...78,974,202
|
|
| G
|
Gimap5
|
GTPase, IMAP family member 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GIMAP5 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 4:79,025,151...79,031,917
Ensembl chr 4:79,024,304...79,039,030
|
|
| G
|
Gimap6
|
GTPase, IMAP family member 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GIMAP6 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 4:78,984,597...78,990,006
Ensembl chr 4:78,983,504...78,990,010
|
|
| G
|
Gimap7
|
GTPase, IMAP family member 7
|
increases expression
|
ISO
|
Nickel results in increased expression of GIMAP7 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 4:79,001,416...79,005,586
Ensembl chr 4:78,999,384...79,006,756
|
|
| G
|
Gimap8
|
GTPase, IMAP family member 8
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GIMAP8 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 4:78,931,003...78,942,491
Ensembl chr 4:78,931,029...78,942,488
|
|
| G
|
Gins2
|
GINS complex subunit 2
|
increases expression
|
ISO
|
Nickel results in increased expression of GINS2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr19:65,535,492...65,548,270
Ensembl chr19:65,535,492...65,548,052
|
|
| G
|
Gipc2
|
GIPC PDZ domain containing family, member 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GIPC2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:243,690,742...243,770,199
Ensembl chr 2:243,690,748...243,770,199
|
|
| G
|
Gja4
|
gap junction protein, alpha 4
|
increases expression
|
ISO
|
Nickel results in increased expression of GJA4 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 5:144,917,791...144,920,324
Ensembl chr 5:144,914,147...144,921,216
|
|
| G
|
Gjc1
|
gap junction protein, gamma 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GJC1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:88,262,840...88,285,646
Ensembl chr10:88,249,489...88,285,853
|
|
| G
|
Gjd3
|
gap junction protein, delta 3
|
increases expression
|
ISO
|
Nickel results in increased expression of GJD3 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr10:84,429,923...84,432,011
Ensembl chr10:84,429,036...84,433,870
|
|
| G
|
Gk5
|
glycerol kinase 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GK5 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 8:105,562,018...105,630,975
Ensembl chr 8:105,562,050...105,631,978
|
|
| G
|
Gkap1
|
G kinase anchoring protein 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GKAP1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr17:6,389,377...6,429,091
Ensembl chr17:6,389,377...6,438,279
|
|
| G
|
Glb1
|
galactosidase, beta 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GLB1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 8:122,963,718...123,036,326
Ensembl chr 8:122,963,718...123,036,326
|
|
| G
|
Glb1l
|
galactosidase, beta 1-like
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GLB1L mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 9:84,141,993...84,154,176
Ensembl chr 9:84,143,841...84,154,176
|
|
| G
|
Glipr1
|
GLI pathogenesis-related 1
|
increases expression
|
ISO
|
Nickel results in increased expression of GLIPR1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:49,373,579...49,399,190
Ensembl chr 7:49,373,581...49,384,640
|
|
| G
|
Glipr2
|
GLI pathogenesis-related 2
|
increases expression
|
ISO
|
Nickel results in increased expression of GLIPR2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:62,966,163...62,998,016
Ensembl chr 5:62,966,195...62,998,716
|
|
| G
|
Glis3
|
GLIS family zinc finger 3
|
increases expression
|
ISO
|
Nickel results in increased expression of GLIS3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:235,389,567...235,809,416
Ensembl chr 1:235,392,651...235,809,221
|
|
| G
|
Glrb
|
glycine receptor, beta
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GLRB mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:168,432,736...168,505,614
Ensembl chr 2:168,432,736...168,505,614
|
|
| G
|
Glrx
|
glutaredoxin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GLRX mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 2:7,073,737...7,083,548
Ensembl chr 2:7,073,759...7,083,543
|
|
| G
|
Glrx3
|
glutaredoxin 3
|
increases expression
|
ISO
|
Nickel results in increased expression of GLRX3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:201,671,410...201,701,722
Ensembl chr 1:201,671,481...201,701,717
|
|
| G
|
Gls
|
glutaminase
|
increases expression
|
ISO
|
Nickel results in increased expression of GLS mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:56,836,584...56,908,861
Ensembl chr 9:56,836,584...56,908,861
|
|
| G
|
Gls2
|
glutaminase 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GLS2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 7:1,201,757...1,218,014
Ensembl chr 7:1,201,838...1,218,013
|
|
| G
|
Glt1d1
|
glycosyltransferase 1 domain containing 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GLT1D1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr12:34,611,942...34,685,591
Ensembl chr12:34,612,643...34,685,468
|
|
| G
|
Glt8d1
|
glycosyltransferase 8 domain containing 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GLT8D1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr16:6,198,152...6,213,671
Ensembl chr16:6,204,740...6,213,668
|
|
| G
|
Glt8d2
|
glycosyltransferase 8 domain containing 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GLT8D2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:22,917,055...22,968,616
Ensembl chr 7:22,917,100...22,968,930
|
|
| G
|
Glul
|
glutamate-ammonia ligase
|
increases expression
|
ISO
|
Nickel results in increased expression of GLUL mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:68,519,500...68,585,554
Ensembl chr13:68,576,067...68,585,520
|
|
| G
|
Gmfb
|
glia maturation factor, beta
|
increases expression
|
ISO
|
Nickel results in increased expression of GMFB mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr15:22,549,705...22,560,125
Ensembl chr15:22,547,034...22,560,308
|
|
| G
|
Gmfg
|
glia maturation factor, gamma
|
increases expression
|
ISO
|
Nickel results in increased expression of GMFG mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:92,856,154...92,866,722
Ensembl chr 1:92,854,995...92,866,723
|
|
| G
|
Gmip
|
Gem-interacting protein
|
increases expression
|
ISO
|
Nickel results in increased expression of GMIP mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr16:19,634,630...19,648,916
Ensembl chr16:19,634,630...19,647,933
|
|
| G
|
Gmppb
|
GDP-mannose pyrophosphorylase B
|
increases expression
|
ISO
|
Nickel results in increased expression of GMPPB mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:117,616,029...117,622,866
|
|
| G
|
Gmpr
|
guanosine monophosphate reductase
|
increases expression
|
ISO
|
Nickel results in increased expression of GMPR mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr17:19,357,992...19,395,807
Ensembl chr17:19,357,992...19,431,655
|
|
| G
|
Gna14
|
G protein subunit alpha 14
|
increases expression
|
ISO
|
Nickel results in increased expression of GNA14 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:223,141,802...223,324,210
Ensembl chr 1:223,141,802...223,324,210
|
|
| G
|
Gna15
|
G protein subunit alpha 15
|
increases expression
|
ISO
|
Nickel results in increased expression of GNA15 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:8,835,396...8,856,269
Ensembl chr 7:8,835,357...8,856,268
|
|
| G
|
Gnao1
|
G protein subunit alpha o1
|
increases expression
|
ISO
|
Nickel results in increased expression of GNAO1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr19:11,040,788...11,198,437
Ensembl chr19:11,040,788...11,198,437
|
|
| G
|
Gnaz
|
G protein subunit alpha z
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GNAZ mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr20:13,642,853...13,693,616
Ensembl chr20:13,644,020...13,669,287
|
|
| G
|
Gnb1
|
G protein subunit beta 1
|
increases expression
|
ISO
|
Nickel results in increased expression of GNB1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:171,357,778...171,424,489
Ensembl chr 5:171,357,797...171,424,488
|
|
| G
|
Gnb2
|
G protein subunit beta 2
|
increases expression
|
ISO
|
Nickel results in increased expression of GNB2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr12:24,795,505...24,800,796
Ensembl chr12:24,795,827...24,800,796
|
|
| G
|
Gng2
|
G protein subunit gamma 2
|
increases expression
|
ISO
|
Nickel results in increased expression of GNG2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr15:4,365,222...4,466,060
Ensembl chr15:4,365,135...4,466,059
|
|
| G
|
Gng7
|
G protein subunit gamma 7
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GNG7 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:9,348,148...9,411,924
Ensembl chr 7:9,348,218...9,411,923
|
|
| G
|
Gnl3l
|
G protein nucleolar 3 like
|
increases expression
|
ISO
|
Nickel results in increased expression of GNL3L mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:23,404,324...23,437,501
Ensembl chr X:23,404,324...23,439,315
|
|
| G
|
Gnpda1
|
glucosamine-6-phosphate deaminase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GNPDA1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr18:30,416,599...30,428,630
Ensembl chr18:30,416,607...30,428,630
|
|
| G
|
Gnrhr
|
gonadotropin releasing hormone receptor
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of GNRHR mRNA trichostatin A inhibits the reaction [Nickel affects the expression of GNRHR mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr14:22,211,666...22,229,654
|
|
| G
|
Gns
|
glucosamine (N-acetyl)-6-sulfatase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GNS mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 7:58,774,625...58,808,650
Ensembl chr 7:58,774,625...58,808,650
|
|
| G
|
Golga5
|
golgin A5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GOLGA5 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 6:127,377,244...127,405,404
Ensembl chr 6:127,377,236...127,405,403
|
|
| G
|
Golph3l
|
golgi phosphoprotein 3-like
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GOLPH3L mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 2:185,840,879...185,872,037
Ensembl chr 2:185,840,958...185,872,043
|
|
| G
|
Golt1b
|
golgi transport 1B
|
increases expression
|
ISO
|
Nickel results in increased expression of GOLT1B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:177,064,071...177,077,165
Ensembl chr 4:177,064,073...177,077,164
|
|
| G
|
Gosr2
|
golgi SNAP receptor complex member 2
|
increases expression
|
ISO
|
Nickel results in increased expression of GOSR2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr10:89,085,323...89,105,665
Ensembl chr10:89,086,331...89,105,637
|
|
| G
|
Gpam
|
glycerol-3-phosphate acyltransferase, mitochondrial
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GPAM mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:264,111,599...264,176,112
Ensembl chr 1:264,113,813...264,175,911
|
|
| G
|
Gpat2
|
glycerol-3-phosphate acyltransferase 2, mitochondrial
|
increases expression
|
ISO
|
Nickel results in increased expression of GPAT2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 3:135,099,751...135,110,355
Ensembl chr 3:135,096,752...135,110,353
|
|
| G
|
Gpat3
|
glycerol-3-phosphate acyltransferase 3
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of GPAT3 mRNA Nickel results in increased expression of GPAT3 mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr14:9,018,762...9,072,552
|
|
| G
|
Gpatch4
|
G patch domain containing 4
|
increases expression
|
ISO
|
Nickel results in increased expression of GPATCH4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:175,797,503...175,816,547
Ensembl chr 2:175,807,682...175,817,358
|
|
| G
|
Gpc3
|
glypican 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GPC3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:136,789,770...137,157,598
Ensembl chr X:136,789,770...137,157,639
|
|
| G
|
Gpc4
|
glypican 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GPC4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:136,565,536...136,676,142
Ensembl chr X:136,565,591...136,676,057
|
|
| G
|
Gpc6
|
glypican 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GPC6 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr15:100,437,415...101,435,038
Ensembl chr15:100,437,943...101,435,027
|
|
| G
|
Gpcpd1
|
glycerophosphocholine phosphodiesterase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of GPCPD1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:140,240,574...140,285,469
Ensembl chr 3:140,240,575...140,285,372
|
|
| G
|
Gpd1
|
glycerol-3-phosphate dehydrogenase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GPD1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:132,722,982...132,730,373
Ensembl chr 7:132,721,915...132,730,368
|
|
| G
|
Gper1
|
G protein-coupled estrogen receptor 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GPER1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr12:20,331,073...20,336,527
Ensembl chr12:20,327,679...20,337,144
|
|
| G
|
Gpihbp1
|
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GPIHBP1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:109,166,334...109,169,448
Ensembl chr 7:109,163,160...109,169,448
|
|
| G
|
Gpld1
|
glycosylphosphatidylinositol specific phospholipase D1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GPLD1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr17:40,512,659...40,560,483
Ensembl chr17:40,512,660...40,554,975
|
|
| G
|
Gpn3
|
GPN-loop GTPase 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GPN3 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr12:39,850,070...39,859,032
Ensembl chr12:39,850,070...39,859,032
|
|
| G
|
Gpnmb
|
glycoprotein nmb
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GPNMB mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 4:79,341,128...79,362,366
Ensembl chr 4:79,341,021...79,380,240
|
|
| G
|
Gpr12
|
G protein-coupled receptor 12
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GPR12 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr12:13,636,549...13,640,083
Ensembl chr12:13,627,055...13,643,650
|
|
| G
|
Gpr132
|
G protein-coupled receptor 132
|
increases expression
|
ISO
|
Nickel results in increased expression of GPR132 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 6:137,745,142...137,763,037
Ensembl chr 6:137,745,241...137,763,157
|
|
| G
|
Gpr141
|
G protein-coupled receptor 141
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GPR141 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr17:49,813,489...49,875,721
Ensembl chr17:49,733,713...49,875,719
|
|
| G
|
Gpr146
|
G protein-coupled receptor 146
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GPR146 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr12:20,365,790...20,381,122
Ensembl chr12:20,364,269...20,381,345
|
|
| G
|
Gpr15lg
|
G protein-coupled receptor 15 ligand
|
increases expression
|
ISO
|
Nickel results in increased expression of GPR15LG mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr16:12,888,528...12,896,134
Ensembl chr16:12,888,528...12,896,134
|
|
| G
|
Gpr171
|
G protein-coupled receptor 171
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of GPR171 mRNA Nickel results in increased expression of GPR171 mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 2:145,510,305...145,515,392
Ensembl chr 2:145,505,549...145,515,592
|
|
| G
|
Gpr18
|
G protein-coupled receptor 18
|
increases expression
|
ISO
|
Nickel results in increased expression of GPR18 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr15:105,404,062...105,407,812
Ensembl chr15:105,404,077...105,408,836
|
|
| G
|
Gpr183
|
G protein-coupled receptor 183
|
increases expression
|
ISO
|
Nickel results in increased expression of GPR183 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr15:105,445,129...105,457,192
Ensembl chr15:105,437,561...105,466,977
|
|
| G
|
Gpr19
|
G protein-coupled receptor 19
|
increases expression
|
ISO
|
Nickel results in increased expression of GPR19 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 4:169,442,278...169,468,805
Ensembl chr 4:169,436,658...169,471,249
|
|
| G
|
Gpr39
|
G protein-coupled receptor 39
|
increases expression
|
ISO
|
Nickel results in increased expression of GPR39 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:39,667,908...39,879,944
Ensembl chr13:39,667,909...39,880,902
|
|
| G
|
Gpr4
|
G protein-coupled receptor 4
|
increases expression
|
ISO
|
Nickel results in increased expression of GPR4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:87,993,398...88,004,568
Ensembl chr 1:87,993,430...88,006,254
|
|
| G
|
Gpr65
|
G-protein coupled receptor 65
|
increases expression
|
ISO
|
Nickel results in increased expression of GPR65 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 6:123,245,534...123,262,758
Ensembl chr 6:123,219,633...123,266,285
|
|
| G
|
Gpr68
|
G protein-coupled receptor 68
|
increases expression
|
ISO
|
Nickel results in increased expression of GPR68 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 6:125,865,205...125,895,674
Ensembl chr 6:125,864,942...125,895,674
|
|
| G
|
Gpr84
|
G protein-coupled receptor 84
|
increases expression
|
ISO
|
Nickel results in increased expression of GPR84 mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr 7:136,322,374...136,324,648
Ensembl chr 7:136,322,191...136,324,703
|
|
| G
|
Gprasp1
|
G protein-coupled receptor associated sorting protein 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GPRASP1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr X:103,556,493...103,564,275
Ensembl chr X:103,501,377...103,565,649
|
|
| G
|
Gprasp2
|
G protein-coupled receptor associated sorting protein 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GPRASP2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr X:103,609,304...103,615,450
Ensembl chr X:103,501,226...103,641,988
|
|
| G
|
Gprin3
|
GPRIN family member 3
|
increases expression
|
ISO
|
Nickel results in increased expression of GPRIN3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:89,902,198...89,987,496
Ensembl chr 4:89,892,867...89,987,565
|
|
| G
|
Gpsm2
|
G-protein signaling modulator 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GPSM2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 2:199,015,250...199,063,788
Ensembl chr 2:199,015,250...199,063,056
|
|
| G
|
Gpsm3
|
G-protein signaling modulator 3
|
increases expression
|
ISO
|
Nickel results in increased expression of GPSM3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr20:4,161,730...4,163,591
Ensembl chr20:4,161,730...4,189,072
|
|
| G
|
Gpt
|
glutamic--pyruvic transaminase
|
multiple interactions
|
EXP
|
[[nickel chloride results in increased abundance of Nickel] co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] results in increased activity of GPT protein; [nickel chloride results in increased abundance of Nickel] which results in increased activity of GPT protein; Fatty Acids, Omega-3 inhibits the reaction [[[nickel chloride results in increased abundance of Nickel] co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] results in increased activity of GPT protein]
|
CTD |
PMID:31639282 |
|
NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160
|
|
| G
|
Gpx1
|
glutathione peroxidase 1
|
decreases expression
|
EXP
|
Nickel results in decreased expression of GPX1 mRNA
|
CTD |
PMID:19440498 |
|
NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581
|
|
| G
|
Gpx2
|
glutathione peroxidase 2
|
decreases expression increases expression
|
EXP ISO
|
Nickel results in decreased expression of GPX2 mRNA Nickel results in increased expression of GPX2 mRNA
|
CTD |
PMID:19440498 PMID:25583101 |
|
NCBI chr 6:101,226,745...101,230,033
Ensembl chr 6:101,226,745...101,230,862
|
|
| G
|
Gpx3
|
glutathione peroxidase 3
|
affects expression
|
EXP
|
Nickel affects the expression of GPX3 mRNA
|
CTD |
PMID:19440498 |
|
NCBI chr10:39,529,335...39,537,406
Ensembl chr10:39,529,448...39,537,405
|
|
| G
|
Gpx4
|
glutathione peroxidase 4
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of GPX4 mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:10,300,832...10,303,629
|
|
| G
|
Gpx6
|
glutathione peroxidase 6
|
decreases expression
|
EXP
|
Nickel results in decreased expression of GPX6 mRNA
|
CTD |
PMID:19440498 |
|
NCBI chr17:48,104,197...48,111,816
Ensembl chr17:48,104,197...48,111,007
|
|
| G
|
Gramd1c
|
GRAM domain containing 1C
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GRAMD1C mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:70,139,076...70,224,478
Ensembl chr11:70,139,184...70,224,478
|
|
| G
|
Grb10
|
growth factor receptor bound protein 10
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GRB10 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr14:90,708,653...90,816,399
Ensembl chr14:90,708,653...90,816,387
|
|
| G
|
Grb14
|
growth factor receptor bound protein 14
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GRB14 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:69,976,331...70,091,921
Ensembl chr 3:69,976,339...70,091,921
|
|
| G
|
Grb2
|
growth factor receptor bound protein 2
|
increases expression
|
ISO
|
Nickel results in increased expression of GRB2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:101,380,354...101,448,138
Ensembl chr10:101,380,356...101,448,138
|
|
| G
|
Greb1
|
growth regulating estrogen receptor binding 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GREB1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:45,169,289...45,321,973
Ensembl chr 6:45,169,289...45,291,126
|
|
| G
|
Grem1
|
gremlin 1, DAN family BMP antagonist
|
increases expression
|
ISO
|
Nickel results in increased expression of GREM1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:120,966,639...120,978,319
Ensembl chr 3:120,966,623...120,979,089
|
|
| G
|
Gria1
|
glutamate ionotropic receptor AMPA type subunit 1
|
increases expression
|
EXP
|
Nickel results in increased expression of GRIA1 mRNA
|
CTD |
PMID:19440498 |
|
NCBI chr10:41,710,540...42,030,105
Ensembl chr10:41,711,080...42,030,309
|
|
| G
|
Gria2
|
glutamate ionotropic receptor AMPA type subunit 2
|
affects expression decreases expression multiple interactions
|
ISO
|
Nickel affects the expression of GRIA2 mRNA Nickel results in decreased expression of GRIA2 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of GRIA2 mRNA]
|
CTD |
PMID:14575637 PMID:24768652 PMID:25583101 |
|
NCBI chr 2:168,247,490...168,367,616
Ensembl chr 2:168,247,496...168,367,616
|
|
| G
|
Gria3
|
glutamate ionotropic receptor AMPA type subunit 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GRIA3 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr X:125,103,975...125,369,690
Ensembl chr X:125,103,782...125,369,679
|
|
| G
|
Grik2
|
glutamate ionotropic receptor kainate type subunit 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GRIK2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr20:53,717,564...54,415,283
Ensembl chr20:53,716,090...54,415,202
|
|
| G
|
Grin2a
|
glutamate ionotropic receptor NMDA type subunit 2A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GRIN2A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:6,136,458...6,560,003
Ensembl chr10:6,138,037...6,551,378
|
|
| G
|
Grin2b
|
glutamate ionotropic receptor NMDA type subunit 2B
|
decreases expression
|
EXP
|
Nickel results in decreased expression of GRIN2B mRNA
|
CTD |
PMID:19440498 |
|
NCBI chr 4:170,297,811...170,775,420
Ensembl chr 4:170,322,617...170,773,570
|
|
| G
|
Grin2c
|
glutamate ionotropic receptor NMDA type subunit 2C
|
decreases expression
|
EXP
|
Nickel results in decreased expression of GRIN2C mRNA
|
CTD |
PMID:19440498 |
|
NCBI chr10:100,987,410...101,006,064
Ensembl chr10:100,987,513...101,005,409
|
|
| G
|
Grin3a
|
glutamate ionotropic receptor NMDA type subunit 3A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GRIN3A mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 5:68,802,333...69,001,880
Ensembl chr 5:68,804,970...69,001,558
|
|
| G
|
Grin3b
|
glutamate ionotropic receptor NMDA type subunit 3B
|
increases expression
|
EXP
|
Nickel results in increased expression of GRIN3B mRNA
|
CTD |
PMID:19440498 |
|
NCBI chr 7:10,381,495...10,387,817
Ensembl chr 7:10,381,496...10,387,817
|
|
| G
|
Grina
|
glutamate ionotropic receptor NMDA type subunit associated protein 1
|
decreases expression
|
EXP
|
Nickel results in decreased expression of GRINA mRNA
|
CTD |
PMID:19440498 |
|
NCBI chr 7:109,842,870...109,846,048
Ensembl chr 7:109,843,196...109,846,042
|
|
| G
|
Grk2
|
G protein-coupled receptor kinase 2
|
increases expression
|
EXP
|
Nickel results in increased expression of GRK2 mRNA
|
CTD |
PMID:18812211 |
|
NCBI chr 1:211,010,259...211,031,013
Ensembl chr 1:211,009,978...211,031,015
|
|
| G
|
Grpel1
|
GrpE-like 1, mitochondrial
|
multiple interactions
|
ISO
|
MT1 affects the reaction [Nickel affects the expression of GRPEL1 mRNA]; MT2 affects the reaction [Nickel affects the expression of GRPEL1 mRNA]
|
CTD |
PMID:16166738 |
|
NCBI chr14:78,517,049...78,522,868
Ensembl chr14:78,517,052...78,522,861
|
|
| G
|
Grtp1
|
growth hormone regulated TBC protein 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GRTP1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr16:83,034,931...83,056,589
|
|
| G
|
Gsdmc
|
gasdermin C
|
increases expression
|
ISO
|
Nickel results in increased expression of GSDMC mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:97,482,713...97,509,985
Ensembl chr 7:97,483,257...97,499,587
|
|
| G
|
Gsdmd
|
gasdermin D
|
increases expression
|
ISO
|
Nickel results in increased expression of GSDMD mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:109,423,209...109,427,771
Ensembl chr 7:109,422,910...109,430,722
|
|
| G
|
Gsn
|
gelsolin
|
affects binding decreases expression
|
ISO
|
GSN protein binds to Nickel Nickel results in decreased expression of GSN mRNA
|
CTD |
PMID:23896426 PMID:25583101 |
|
NCBI chr 3:38,982,605...39,035,849
Ensembl chr 3:38,982,671...39,035,850
|
|
| G
|
Gspt1
|
G1 to S phase transition 1
|
increases expression
|
ISO
|
Nickel results in increased expression of GSPT1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:4,867,687...4,904,186
Ensembl chr10:4,869,465...4,908,040
|
|
| G
|
Gsr
|
glutathione-disulfide reductase
|
multiple interactions
|
EXP
|
[Arsenic co-treated with Cadmium co-treated with Lead co-treated with Mercury co-treated with Chromium co-treated with Nickel co-treated with Manganese co-treated with Iron] results in decreased activity of GSR protein
|
CTD |
PMID:17176674 |
|
NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394
|
|
| G
|
Gsta1
|
glutathione S-transferase alpha 1
|
increases expression
|
ISO
|
Nickel results in increased expression of GSTA1 mRNA
|
CTD |
PMID:14971665 |
|
NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:31,199,888...31,211,528
|
|
| G
|
Gsta5
|
glutathione S-transferase alpha 5
|
affects expression decreases expression
|
EXP
|
Nickel affects the expression of GSTA5 mRNA Nickel results in decreased expression of GSTA5 mRNA
|
CTD |
PMID:19440498 |
|
NCBI chr 8:87,985,768...87,997,766
Ensembl chr 8:87,985,258...87,997,765
|
|
| G
|
Gstk1
|
glutathione S-transferase kappa 1
|
decreases expression
|
EXP
|
Nickel results in decreased expression of GSTK1 mRNA
|
CTD |
PMID:19440498 |
|
NCBI chr 4:72,085,532...72,089,934
Ensembl chr 4:72,085,531...72,089,927
|
|
| G
|
Gstm1
|
glutathione S-transferase mu 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GSTM1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:198,338,008...198,343,569
|
|
| G
|
Gstm2
|
glutathione S-transferase mu 2
|
decreases expression
|
EXP ISO
|
Nickel results in decreased expression of GSTM2 mRNA
|
CTD |
PMID:19440498 PMID:24768652 PMID:25583101 |
|
NCBI chr 2:198,312,179...198,316,962
|
|
| G
|
Gstm4
|
glutathione S-transferase mu 4
|
affects expression decreases expression
|
EXP ISO
|
Nickel affects the expression of GSTM4 mRNA Nickel results in decreased expression of GSTM4 mRNA
|
CTD |
PMID:19440498 PMID:24768652 PMID:25583101 |
|
NCBI chr 2:198,356,114...198,373,487
Ensembl chr 2:198,358,744...198,373,638
|
|
| G
|
Gstm5
|
glutathione S-transferase, mu 5
|
affects expression decreases expression multiple interactions
|
ISO EXP
|
Nickel affects the expression of GSTM3 mRNA Nickel results in decreased expression of GSTM3 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of GSTM3 mRNA]
|
CTD |
PMID:14575637 PMID:19440498 PMID:24768652 PMID:25583101 |
|
NCBI chr 2:198,219,769...198,222,732
Ensembl chr 2:198,219,647...198,222,731
|
|
| G
|
Gstm5l
|
glutathione S-transferase, mu 5-like
|
decreases expression
|
ISO EXP
|
Nickel results in decreased expression of GSTM5 mRNA
|
CTD |
PMID:19440498 PMID:25583101 |
|
NCBI chr 2:198,231,285...198,238,122
Ensembl chr 2:198,232,596...198,238,252
|
|
| G
|
Gstm6
|
glutathione S-transferase, mu 6
|
affects expression
|
EXP
|
Nickel affects the expression of GSTM6 mRNA
|
CTD |
PMID:19440498 |
|
NCBI chr 2:198,267,734...198,272,508
|
|
| G
|
Gsto1
|
glutathione S-transferase omega 1
|
decreases expression
|
EXP
|
Nickel results in decreased expression of GSTO1 mRNA
|
CTD |
PMID:19440498 |
|
NCBI chr 1:256,662,377...256,672,515
Ensembl chr 1:256,662,531...256,676,167
|
|
| G
|
Gsto2
|
glutathione S-transferase omega 2
|
decreases expression
|
EXP
|
Nickel results in decreased expression of GSTO2 mRNA
|
CTD |
PMID:19440498 |
|
NCBI chr 1:256,673,376...256,695,154
Ensembl chr 1:256,673,274...256,695,146
|
|
| G
|
Gstp1
|
glutathione S-transferase pi 1
|
decreases expression
|
EXP
|
Nickel results in decreased expression of GSTP2 mRNA
|
CTD |
PMID:19440498 |
|
NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705
|
|
| G
|
Gstt1
|
glutathione S-transferase theta 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GSTT1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr20:12,856,068...12,873,020
Ensembl chr20:12,856,083...12,873,019
|
|
| G
|
Gstt3
|
glutathione S-transferase, theta 3
|
decreases expression
|
EXP
|
Nickel results in decreased expression of GSTT3 mRNA
|
CTD |
PMID:19440498 |
|
NCBI chr20:12,873,618...12,881,974
Ensembl chr20:12,874,374...12,881,973
|
|
| G
|
Gtf2e1
|
general transcription factor IIE subunit 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GTF2E1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr11:76,687,382...76,720,253
Ensembl chr11:76,687,772...76,720,784
|
|
| G
|
Gtf2h1
|
general transcription factor IIH subunit 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GTF2H1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 1:106,457,692...106,485,729
Ensembl chr 1:106,457,394...106,485,727
|
|
| G
|
Gtf2h5
|
general transcription factor IIH subunit 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GTF2H5 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:49,061,904...49,068,612
Ensembl chr 1:49,061,959...49,070,039
|
|
| G
|
Gucy1a1
|
guanylate cyclase 1 soluble subunit alpha 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GUCY1A1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:169,716,684...169,780,360
Ensembl chr 2:169,716,709...169,779,737
|
|
| G
|
Gucy1a2
|
guanylate cyclase 1 soluble subunit alpha 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GUCY1A2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:8,785,212...9,174,322
Ensembl chr 8:8,785,121...9,174,272
|
|
| G
|
Gvin1
|
GTPase, very large interferon inducible 1
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of GVINP1 mRNA Nickel results in increased expression of GVINP1 mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr 1:169,689,178...169,718,522
Ensembl chr 1:169,691,586...169,718,522
|
|
| G
|
Gxylt2
|
glucoside xylosyltransferase 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of GXYLT2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:134,903,595...135,006,066
Ensembl chr 4:134,903,859...134,987,956
|
|
| G
|
Gzma
|
granzyme A
|
increases expression
|
ISO
|
Nickel results in increased expression of GZMA mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:46,473,763...46,485,696
Ensembl chr 2:46,473,763...46,485,696
|
|
| G
|
Gzmb
|
granzyme B
|
increases expression
|
ISO
|
Nickel results in increased expression of GZMB mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr15:34,459,007...34,462,469
Ensembl chr15:34,459,007...34,462,469
|
|
| G
|
Gzmf
|
granzyme F
|
increases expression
|
ISO
|
Nickel results in increased expression of GZMH mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr15:33,975,543...33,997,505
Ensembl chr15:33,977,505...33,997,572
|
|
| G
|
Gzmk
|
granzyme K
|
increases expression
|
ISO
|
Nickel results in increased expression of GZMK mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:46,573,997...46,582,015
Ensembl chr 2:46,573,997...46,582,015
|
|
| G
|
H19
|
H19 imprinted maternally expressed transcript
|
decreases expression
|
ISO
|
Nickel results in decreased expression of H19 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:207,160,175...207,162,851
|
|
| G
|
H1f2
|
H1.2 linker histone, cluster member
|
increases expression
|
ISO
|
Nickel results in increased expression of H1F2 mRNA
|
CTD |
PMID:18922574 |
|
NCBI chr17:41,818,962...41,820,453
Ensembl chr17:41,779,051...41,822,317
|
|
| G
|
H2ac20
|
H2A clustered histone 20
|
decreases ubiquitination increases ubiquitination
|
ISO
|
Nickel results in decreased ubiquitination of H2AC20 protein Nickel results in increased ubiquitination of H2AC20 protein
|
CTD |
PMID:16870173 |
|
NCBI chr 2:186,468,748...186,469,226
|
|
| G
|
H2aj
|
H2A.J histone
|
decreases expression
|
ISO
|
Nickel results in decreased expression of H2AJ mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:171,406,922...171,407,406
Ensembl chr 4:171,406,177...171,408,845
|
|
| G
|
H2ax
|
H2A.X variant histone
|
increases expression multiple interactions
|
ISO
|
Nickel results in increased expression of H2AX mRNA [Asbestos, Serpentine results in increased abundance of [Magnesium co-treated with Chromium co-treated with Nickel co-treated with Cobalt]] which results in increased phosphorylation of H2AX protein
|
CTD |
PMID:25583101 PMID:38605572 |
|
NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
|
|
| G
|
H2bc27
|
H2B clustered histone 27
|
increases methylation increases ubiquitination decreases methylation decreases ubiquitination
|
ISO
|
Nickel results in increased methylation of H2BC26 protein Nickel results in increased ubiquitination of H2BC26 protein Nickel results in decreased methylation of H2BC26 protein Nickel results in decreased ubiquitination of H2BC26 protein
|
CTD |
PMID:16870173 |
|
NCBI chr10:44,232,318...44,233,065
Ensembl chr10:44,232,318...44,233,065
|
|
| G
|
H3f4
|
H3.4 histone, cluster member
|
multiple interactions increases methylation
|
ISO
|
[Arsenic co-treated with Nickel] results in increased acetylation of H3-4 protein; [Arsenic co-treated with Nickel] results in increased methylation of H3-4 protein Nickel results in increased methylation of H3-4 protein
|
CTD |
PMID:16648469 PMID:21385672 |
|
NCBI chr10:44,240,282...44,240,842
|
|
| G
|
H6pd
|
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
|
increases expression
|
ISO
|
Nickel results in increased expression of H6PD mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:165,717,456...165,753,158
Ensembl chr 5:165,721,654...165,753,125
|
|
| G
|
Hacd2
|
3-hydroxyacyl-CoA dehydratase 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HACD2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr11:79,175,470...79,268,975
Ensembl chr11:79,175,482...79,268,126
|
|
| G
|
Hacl1
|
2-hydroxyacyl-CoA lyase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HACL1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr16:6,831,293...6,869,410
Ensembl chr16:6,833,268...6,869,410
|
|
| G
|
Hadh
|
hydroxyacyl-CoA dehydrogenase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HADH mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:222,462,049...222,504,446
Ensembl chr 2:222,462,049...222,504,446
|
|
| G
|
Hal
|
histidine ammonia lyase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HAL mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 7:29,894,495...29,924,744
Ensembl chr 7:29,893,855...29,924,744
|
|
| G
|
Hao2
|
hydroxyacid oxidase 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HAO2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 2:188,888,848...188,921,567
Ensembl chr 2:188,889,212...188,913,133
|
|
| G
|
Hapln3
|
hyaluronan and proteoglycan link protein 3
|
increases expression
|
ISO
|
Nickel results in increased expression of HAPLN3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:142,455,828...142,473,877
Ensembl chr 1:142,454,629...142,471,832
|
|
| G
|
Hapstr1
|
HUWE1 associated protein modifying stress responses
|
increases expression
|
ISO
|
Nickel results in increased expression of HAPSTR1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:7,252,737...7,281,678
Ensembl chr10:7,252,737...7,281,678
|
|
| G
|
Has3
|
hyaluronan synthase 3
|
increases expression
|
ISO
|
Nickel results in increased expression of HAS3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr19:51,668,276...51,691,042
|
|
| G
|
Havcr2
|
hepatitis A virus cellular receptor 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HAVCR2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr10:31,383,801...31,415,334
Ensembl chr10:31,383,925...31,413,872
|
|
| G
|
Hba-a1
|
hemoglobin alpha, adult chain 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HBA mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr10:15,841,724...15,842,580
Ensembl chr10:15,841,763...15,842,603
|
|
| G
|
Hba-a3
|
hemoglobin alpha, adult chain 3
|
affects binding
|
ISO
|
HBA2 protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr10:15,816,099...15,816,943
Ensembl chr10:15,816,096...15,817,167
|
|
| G
|
Hbb
|
hemoglobin subunit beta
|
affects binding decreases expression
|
ISO
|
HBB protein binds to Nickel Nickel results in decreased expression of HBB mRNA
|
CTD |
PMID:23896426 PMID:25583101 |
|
NCBI chr 1:167,662,310...167,663,721
Ensembl chr 1:167,630,245...167,663,873
|
|
| G
|
Hbegf
|
heparin-binding EGF-like growth factor
|
increases expression
|
ISO
|
Nickel results in increased expression of HBEGF mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr18:28,380,337...28,390,220
Ensembl chr18:28,380,337...28,390,220
|
|
| G
|
Hbp1
|
HMG-box transcription factor 1
|
increases expression
|
ISO
|
Nickel results in increased expression of HBP1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 6:54,257,118...54,283,373
Ensembl chr 6:54,256,864...54,283,366
|
|
| G
|
Hck
|
HCK proto-oncogene, Src family tyrosine kinase
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of HCK mRNA Nickel results in increased expression of HCK mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr 3:162,031,833...162,074,933
Ensembl chr 3:162,031,817...162,074,935
|
|
| G
|
Hcls1
|
hematopoietic cell specific Lyn substrate 1
|
increases expression
|
ISO
|
Nickel results in increased expression of HCLS1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr11:77,322,873...77,346,333
Ensembl chr11:77,322,873...77,346,387
|
|
| G
|
Hcn3
|
hyperpolarization-activated cyclic nucleotide-gated potassium channel 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HCN3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:176,849,635...176,867,726
Ensembl chr 2:176,849,635...176,868,538
|
|
| G
|
Hcst
|
hematopoietic cell signal transducer
|
increases expression
|
ISO
|
Nickel results in increased expression of HCST mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:94,804,429...94,806,661
Ensembl chr 1:94,804,430...94,806,641
|
|
| G
|
Hdac5
|
histone deacetylase 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HDAC5 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:87,653,139...87,688,078
Ensembl chr10:87,652,656...87,694,244
|
|
| G
|
Hdac8
|
histone deacetylase 8
|
affects binding
|
ISO
|
Nickel binds to HDAC8 protein
|
CTD |
PMID:16681389 |
|
NCBI chr X:71,425,240...71,632,865
Ensembl chr X:71,394,928...71,632,865
|
|
| G
|
Hdc
|
histidine decarboxylase
|
increases expression affects response to substance
|
ISO
|
Nickel results in increased expression of HDC mRNA HDC affects the susceptibility to Nickel
|
CTD |
PMID:19839048 PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 3:134,300,628...134,318,704
Ensembl chr 3:134,300,632...134,318,711
|
|
| G
|
Hdhd2
|
haloacid dehalogenase-like hydrolase domain containing 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HDHD2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr18:72,763,313...72,801,679
Ensembl chr18:72,749,976...72,801,679
|
|
| G
|
Heatr3
|
HEAT repeat containing 3
|
increases expression
|
ISO
|
Nickel results in increased expression of HEATR3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr19:35,065,915...35,103,779
Ensembl chr19:35,067,060...35,103,978
|
|
| G
|
Heg1
|
heart development protein with EGF-like domains 1
|
increases expression
|
ISO
|
Nickel results in increased expression of HEG1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:80,512,096...80,600,150
Ensembl chr11:80,512,096...80,600,092
|
|
| G
|
Helb
|
DNA helicase B
|
increases expression
|
ISO
|
Nickel results in increased expression of HELB mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 7:57,474,115...57,502,221
Ensembl chr 7:57,474,184...57,501,225
|
|
| G
|
Hells
|
helicase, lymphoid specific
|
increases expression
|
ISO
|
Nickel results in increased expression of HELLS mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:246,113,580...246,159,230
Ensembl chr 1:246,114,096...246,159,228
|
|
| G
|
Helz2
|
helicase with zinc finger 2
|
increases expression
|
ISO
|
Nickel results in increased expression of HELZ2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:188,716,370...188,730,776
Ensembl chr 3:188,716,370...188,730,716
|
|
| G
|
Heph
|
hephaestin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HEPH mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:65,160,628...65,412,457
Ensembl chr X:65,305,773...65,412,453
|
|
| G
|
Herc4
|
HECT and RLD domain containing E3 ubiquitin protein ligase 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HERC4 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr20:25,329,005...25,403,443
Ensembl chr20:25,328,822...25,403,372
|
|
| G
|
Herc6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
increases expression
|
ISO
|
Nickel results in increased expression of HERC6 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:88,854,612...88,897,043
Ensembl chr 4:88,854,640...88,896,993
|
|
| G
|
Hey1
|
hes-related family bHLH transcription factor with YRPW motif 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HEY1 mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr 2:95,003,935...95,006,457
Ensembl chr 2:95,002,943...95,007,624
|
|
| G
|
Hey2
|
hes-related family bHLH transcription factor with YRPW motif 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HEY2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:28,641,100...28,651,187
Ensembl chr 1:28,641,057...28,651,187
|
|
| G
|
Hgd
|
homogentisate 1, 2-dioxygenase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HGD mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr11:76,592,202...76,643,776
Ensembl chr11:76,592,204...76,643,767
|
|
| G
|
Hhex
|
hematopoietically expressed homeobox
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HHEX mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 1:244,602,945...244,608,532
Ensembl chr 1:244,602,825...244,608,604
|
|
| G
|
Hibadh
|
3-hydroxyisobutyrate dehydrogenase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HIBADH mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:82,979,759...83,077,819
Ensembl chr 4:82,979,765...83,111,242
|
|
| G
|
Hid1
|
HID1 domain containing
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HID1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:101,088,526...101,109,011
Ensembl chr10:101,088,526...101,109,011
|
|
| G
|
Hif1a
|
hypoxia inducible factor 1 subunit alpha
|
multiple interactions increases expression affects response to substance affects localization increases stability decreases expression
|
ISO EXP
|
[nickel chloride results in increased abundance of Nickel] which results in increased expression of and results in decreased hydroxylation of HIF1A protein; [Nickel co-treated with Arsenic] results in increased expression of HIF1A protein; [Nickel co-treated with Chromium] results in increased expression of HIF1A protein; chromium hexavalent ion inhibits the reaction [Nickel results in increased stability of and results in increased expression of HIF1A protein]; ferric sulfate inhibits the reaction [Nickel results in increased stability of HIF1A protein]; ferrous sulfate inhibits the reaction [Nickel results in increased expression of HIF1A protein]; HIF1A mRNA affects the reaction [Nickel results in increased expression of KDM3A mRNA]; HIF1A mRNA affects the reaction [Nickel results in increased expression of KDM3A protein]; HIF1A protein promotes the reaction [Nickel results in increased expression of NDRG1 mRNA]; HIF1A protein promotes the reaction [Nickel results in increased expression of NDRG1 protein]; HIF1A protein promotes the reaction [Nickel results in increased expression of SERPINE1 mRNA]; Iron inhibits the reaction [Nickel results in increased stability of HIF1A protein]; Nickel results in increased expression of and results in decreased degradation of HIF1A protein; Nickel results in increased stability of and results in increased expression of and results in increased activity of HIF1A protein; Nickel results in increased stability of and results in increased expression of HIF1A protein; STAT1 protein affects the reaction [chromium hexavalent ion inhibits the reaction [Nickel results in increased stability of and results in increased expression of HIF1A protein]]; U 0126 inhibits the reaction [Nickel results in increased expression of HIF1A protein] Nickel analog results in increased expression of HIF1A protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [PDGFB protein promotes the reaction [Nickel analog results in increased expression of HIF1A protein]]; Acetylcysteine inhibits the reaction [Nickel analog results in increased expression of HIF1A protein]; Acetylcysteine inhibits the reaction [PDGFB protein promotes the reaction [Nickel analog results in increased expression of HIF1A protein]]; PDGFB protein promotes the reaction [Nickel analog results in increased expression of HIF1A protein] HIF1A affects the susceptibility to Nickel Nickel affects the localization of HIF1A protein Nickel results in decreased expression of HIF1A mRNA
|
CTD |
PMID:11504687 PMID:15341671 PMID:16386771 PMID:16877034 PMID:19403854 PMID:20881000 PMID:21401309 PMID:22700867 PMID:35504338 More...
|
|
NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323
|
|
| G
|
Hif3a
|
hypoxia inducible factor 3 subunit alpha
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HIF3A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:86,846,196...86,878,527
Ensembl chr 1:86,850,554...86,877,838
|
|
| G
|
Hilpda
|
hypoxia inducible lipid droplet-associated
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HILPDA mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 4:58,836,463...58,839,423
Ensembl chr 4:58,836,463...58,839,423
|
|
| G
|
Hivep1
|
HIVEP zinc finger 1
|
increases expression
|
ISO
|
Nickel results in increased expression of HIVEP1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr17:22,790,855...22,920,359
Ensembl chr17:22,790,855...22,917,196
|
|
| G
|
Hk2
|
hexokinase 2
|
increases expression multiple interactions
|
ISO
|
Nickel results in increased expression of HK2 mRNA Celecoxib inhibits the reaction [Nickel results in increased expression of HK2 mRNA]; Dexamethasone inhibits the reaction [Nickel results in increased expression of HK2 mRNA]; Indomethacin inhibits the reaction [Nickel results in increased expression of HK2 mRNA]
|
CTD |
PMID:24768652 PMID:25583101 PMID:27452194 |
|
NCBI chr 4:116,792,258...116,841,275
Ensembl chr 4:116,792,258...116,841,275
|
|
| G
|
Hlf
|
HLF transcription factor, PAR bZIP family member
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HLF mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr10:75,651,320...75,708,979
Ensembl chr10:75,654,534...75,708,619
|
|
| G
|
Hltf
|
helicase-like transcription factor
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HLTF mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 2:104,478,725...104,538,531
Ensembl chr 2:104,478,772...104,538,818
|
|
| G
|
Hm13
|
histocompatibility minor 13
|
increases expression
|
ISO
|
Nickel results in increased expression of HM13 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 3:161,606,059...161,641,382
Ensembl chr 3:161,606,052...161,644,805
|
|
| G
|
Hmbs
|
hydroxymethylbilane synthase
|
increases expression
|
ISO
|
Nickel results in increased expression of HMBS mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:53,570,364...53,577,758
Ensembl chr 8:53,570,364...53,577,802
|
|
| G
|
Hmcn1
|
hemicentin 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HMCN1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:65,165,532...65,634,681
Ensembl chr13:65,165,532...65,634,519
|
|
| G
|
Hmgcs1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of HMGCS1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:53,382,643...53,399,802
|
|
| G
|
Hmgcs2
|
3-hydroxy-3-methylglutaryl-CoA synthase 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HMGCS2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:188,564,348...188,590,872
Ensembl chr 2:188,547,767...188,592,242
|
|
| G
|
Hmox1
|
heme oxygenase 1
|
multiple interactions decreases expression increases expression
|
ISO
|
Lipopolysaccharides promotes the reaction [Nickel results in increased expression of HMOX1 protein] Nickel results in decreased expression of HMOX1 mRNA [Particulate Matter co-treated with Nickel] results in increased expression of HMOX1 mRNA Nickel results in increased expression of HMOX1 mRNA Nickel results in increased expression of HMOX1 mRNA; Nickel results in increased expression of HMOX1 protein
|
CTD |
PMID:19033392 PMID:23195993 PMID:23788629 |
|
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
|
|
| G
|
Hmx1
|
H6 family homeobox 1
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of HMX1 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of HMX1 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr14:79,585,840...79,589,626
Ensembl chr14:79,585,840...79,589,626
|
|
| G
|
Hnf1b
|
HNF1 homeobox B
|
multiple interactions affects expression
|
ISO
|
trichostatin A inhibits the reaction [Nickel affects the expression of HNF1B mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr10:69,233,377...69,287,360
Ensembl chr10:69,233,131...69,287,361
|
|
| G
|
Hnmt
|
histamine N-methyltransferase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HNMT mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:26,978,274...27,010,291
Ensembl chr 3:26,977,933...27,010,482
|
|
| G
|
Hnrnpf
|
heterogeneous nuclear ribonucleoprotein F
|
increases expression
|
ISO
|
Nickel results in increased expression of HNRNPF mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:152,755,668...152,776,867
Ensembl chr 4:152,722,617...152,815,769
|
|
| G
|
Hnrnpk
|
heterogeneous nuclear ribonucleoprotein K
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HNRNPK mRNA
|
CTD |
PMID:18922574 |
|
NCBI chr17:6,269,302...6,280,429
Ensembl chr17:6,268,385...6,280,565
|
|
| G
|
Hoxa2
|
homeobox A2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HOXA2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:82,593,389...82,597,589
Ensembl chr 4:82,593,389...82,595,692
|
|
| G
|
Hoxa3
|
homeobox A3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HOXA3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:82,599,860...82,643,831
Ensembl chr 4:82,599,860...82,643,831
|
|
| G
|
Hoxa5
|
homeo box A5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HOXA5 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:82,632,958...82,636,851
Ensembl chr 4:82,632,306...82,639,038
|
|
| G
|
Hoxa7
|
homeobox A7
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HOXA7 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:82,646,342...82,652,449
Ensembl chr 4:82,646,364...82,648,241
|
|
| G
|
Hoxb3
|
homeo box B3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HOXB3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:81,786,001...81,810,655
Ensembl chr10:81,795,882...81,809,628
|
|
| G
|
Hoxb5
|
homeo box B5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HOXB5 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:81,765,911...81,768,119
|
|
| G
|
Hoxb7
|
homeo box B7
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HOXB7 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:81,749,159...81,752,577
Ensembl chr10:81,749,097...81,752,550
|
|
| G
|
Hoxc10
|
homeo box C10
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HOXC10 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:135,982,222...135,987,442
Ensembl chr 7:135,982,065...135,986,712
|
|
| G
|
Hoxc11
|
homeobox C11
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HOXC11 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 7:135,969,707...135,973,222
Ensembl chr 7:135,969,989...135,973,222
|
|
| G
|
Hoxc9
|
homeobox C9
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HOXC9 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:135,997,292...135,999,969
Ensembl chr 7:135,992,023...135,999,964
|
|
| G
|
Hoxd1
|
homeo box D1
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of HOXD1 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of HOXD1 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 3:80,073,041...80,075,180
Ensembl chr 3:80,073,041...80,075,180
|
|
| G
|
Hoxd3
|
homeo box D3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HOXD3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:80,041,598...80,057,700
Ensembl chr 3:80,046,126...80,057,700
|
|
| G
|
Hoxd4
|
homeo box D4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HOXD4 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 3:80,021,886...80,041,462
Ensembl chr 3:80,036,900...80,038,948
|
|
| G
|
Hp
|
haptoglobin
|
affects binding increases expression
|
ISO
|
HP protein binds to Nickel Nickel results in increased expression of HP mRNA
|
CTD |
PMID:23896426 PMID:24768652 PMID:25583101 |
|
NCBI chr19:54,449,151...54,453,701
Ensembl chr19:54,446,217...54,467,518
|
|
| G
|
Hps1
|
HPS1, biogenesis of lysosomal organelles complex 3 subunit 1
|
increases expression
|
ISO
|
Nickel results in increased expression of HPS1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:251,500,427...251,526,529
Ensembl chr 1:251,500,427...251,526,739
|
|
| G
|
Hps3
|
HPS3, biogenesis of lysosomal organelles complex 2 subunit 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HPS3 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 2:104,413,618...104,455,091
Ensembl chr 2:104,413,417...104,455,091
|
|
| G
|
Hpse
|
heparanase
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of HPSE mRNA Nickel results in increased expression of HPSE mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr14:9,200,971...9,241,377
Ensembl chr14:9,188,275...9,241,754
|
|
| G
|
Hpx
|
hemopexin
|
affects binding
|
ISO
|
HPX protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr 1:169,344,647...169,352,155
Ensembl chr 1:169,344,583...169,352,156
|
|
| G
|
Hrct1
|
histidine rich carboxyl terminus 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HRCT1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:62,778,112...62,778,954
Ensembl chr 5:62,778,112...62,778,954
|
|
| G
|
Hrg
|
histidine-rich glycoprotein
|
affects binding
|
ISO
|
HRG protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr11:91,559,087...91,573,982
Ensembl chr11:91,559,091...91,573,982
|
|
| G
|
Hrh1
|
histamine receptor H 1
|
affects response to substance increases expression
|
ISO
|
HRH1 affects the susceptibility to Nickel Nickel results in increased expression of HRH1 mRNA
|
CTD |
PMID:19839048 PMID:24768652 PMID:25583101 |
|
NCBI chr 4:149,120,511...149,204,267
Ensembl chr 4:149,120,039...149,208,248
|
|
| G
|
Hrnr
|
hornerin
|
affects binding
|
ISO
|
HRNR protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr 2:181,650,772...181,663,633
|
|
| G
|
Hs3st1
|
heparan sulfate-glucosamine 3-sulfotransferase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of HS3ST1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr14:75,398,101...75,429,628
Ensembl chr14:75,398,026...75,436,848
|
|
| G
|
Hs3st3a1
|
heparan sulfate-glucosamine 3-sulfotransferase 3A1
|
increases expression
|
ISO
|
Nickel results in increased expression of HS3ST3A1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:49,593,208...49,679,854
Ensembl chr10:49,593,009...49,679,854
|
|
| G
|
Hs3st3b1
|
heparan sulfate-glucosamine 3-sulfotransferase 3B1
|
increases expression
|
ISO
|
Nickel results in increased expression of HS3ST3B1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:49,060,693...49,093,185
Ensembl chr10:49,060,693...49,093,185
|
|
| G
|
Hs3st6
|
heparan sulfate-glucosamine 3-sulfotransferase 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HS3ST6 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr10:14,286,555...14,292,660
Ensembl chr10:14,286,507...14,292,660
|
|
| G
|
Hs6st3
|
heparan sulfate 6-O-sulfotransferase 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HS6ST3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr15:102,688,420...103,407,725
Ensembl chr15:102,688,365...103,408,384
|
|
| G
|
Hsd11b1
|
hydroxysteroid 11-beta dehydrogenase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HSD11B1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr13:107,277,526...107,327,462
Ensembl chr13:107,257,239...107,327,432
|
|
| G
|
Hsd11b2
|
hydroxysteroid 11-beta dehydrogenase 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HSD11B2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr19:50,307,569...50,312,812
Ensembl chr19:50,307,569...50,312,812
|
|
| G
|
Hsd17b4
|
hydroxysteroid (17-beta) dehydrogenase 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HSD17B4 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr18:45,515,427...45,604,467
Ensembl chr18:45,515,373...45,604,467
|
|
| G
|
Hsd17b6
|
hydroxysteroid (17-beta) dehydrogenase 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HSD17B6 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:831,407...850,950
Ensembl chr 7:831,421...850,873
|
|
| G
|
Hsd17b7
|
hydroxysteroid (17-beta) dehydrogenase 7
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of HSD17B7 mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr13:84,702,875...84,722,810
Ensembl chr13:84,705,631...84,722,754
|
|
| G
|
Hsh2d
|
hematopoietic SH2 domain containing
|
increases expression
|
ISO
|
Nickel results in increased expression of HSH2D mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr16:17,664,548...17,686,976
Ensembl chr16:17,669,345...17,682,013
|
|
| G
|
Hsp90aa1
|
heat shock protein 90 alpha family class A member 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HSP90AA1 mRNA
|
CTD |
PMID:18922574 |
|
NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499
|
|
| G
|
Hspa13
|
heat shock protein family A (Hsp70) member 13
|
increases expression
|
ISO
|
Nickel results in increased expression of HSPA13 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:27,862,717...27,876,898
Ensembl chr11:27,862,593...27,876,898
|
|
| G
|
Hspa1a
|
heat shock protein family A (Hsp70) member 1A
|
multiple interactions
|
EXP
|
[Nickel co-treated with Cobalt co-treated with Tungsten] results in increased expression of HSPA1A mRNA; [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of HSPA1A mRNA
|
CTD |
PMID:22198552 |
|
NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979
|
|
| G
|
Hspa1l
|
heat shock protein family A (Hsp70) member 1 like
|
multiple interactions affects expression
|
ISO
|
trichostatin A inhibits the reaction [Nickel affects the expression of HSPA1L mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr20:3,853,496...3,860,223
Ensembl chr20:3,853,331...3,876,877
|
|
| G
|
Hspa2
|
heat shock protein family A (Hsp70) member 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HSPA2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:100,864,172...100,866,946
Ensembl chr 6:100,864,553...100,867,133
|
|
| G
|
Hspa5
|
heat shock protein family A (Hsp70) member 5
|
multiple interactions
|
EXP
|
Nickel inhibits the reaction [lead acetate binds to HSPA5 protein]
|
CTD |
PMID:10702365 |
|
NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790
|
|
| G
|
Hspa6l-ps1
|
heat shock protein family A (Hsp70) member 6 like, pseudogene 1
|
increases expression
|
ISO
|
Nickel results in increased expression of HSPA6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:85,805,911...85,807,052
|
|
| G
|
Hspa8
|
heat shock protein family A (Hsp70) member 8
|
multiple interactions
|
EXP
|
[Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of HSPA8 mRNA
|
CTD |
PMID:22198552 |
|
NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:50,080,199...50,084,372
|
|
| G
|
Hspb1
|
heat shock protein family B (small) member 1
|
multiple interactions
|
EXP
|
[Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of HSPB1 mRNA
|
CTD |
PMID:22198552 |
|
NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301
|
|
| G
|
Hspb2
|
heat shock protein family B (small) member 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HSPB2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:59,989,640...59,991,215
Ensembl chr 8:59,976,623...59,990,901
|
|
| G
|
Hspb6
|
heat shock protein family B (small) member 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HSPB6 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:94,934,372...94,936,516
Ensembl chr 1:94,933,543...94,936,512
|
|
| G
|
Hspb7
|
heat shock protein family B (small) member 7
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HSPB7 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:159,010,759...159,014,245
Ensembl chr 5:159,010,629...159,014,243
|
|
| G
|
Hspd1
|
heat shock protein family D (Hsp60) member 1
|
increases expression
|
ISO
|
Nickel results in increased expression of HSPD1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:64,073,611...64,084,037
|
|
| G
|
Hsph1
|
heat shock protein family H (Hsp110) member 1
|
multiple interactions increases expression
|
EXP ISO
|
[Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of HSPH1 mRNA Nickel results in increased expression of HSPH1 mRNA
|
CTD |
PMID:22198552 PMID:24768652 PMID:25583101 |
|
NCBI chr12:10,427,368...10,446,602
Ensembl chr12:10,427,297...10,446,891
|
|
| G
|
Htr1d
|
5-hydroxytryptamine receptor 1D
|
affects expression
|
EXP
|
Nickel affects the expression of HTR1D mRNA
|
CTD |
PMID:18835401 |
|
NCBI chr 5:153,939,735...153,960,012
Ensembl chr 5:153,939,516...153,960,012
|
|
| G
|
Htr2a
|
5-hydroxytryptamine receptor 2A
|
decreases expression
|
EXP
|
Nickel results in decreased expression of HTR2A mRNA
|
CTD |
PMID:18835401 |
|
NCBI chr15:56,360,647...56,428,703
Ensembl chr15:56,359,596...56,431,619
|
|
| G
|
Htr3a
|
5-hydroxytryptamine receptor 3A
|
affects expression
|
EXP
|
Nickel affects the expression of HTR3A mRNA
|
CTD |
PMID:18835401 |
|
NCBI chr 8:58,138,514...58,150,960
Ensembl chr 8:58,138,226...58,150,884
|
|
| G
|
Htr3b
|
5-hydroxytryptamine receptor 3B
|
decreases expression
|
EXP
|
Nickel results in decreased expression of HTR3B mRNA
|
CTD |
PMID:18835401 |
|
NCBI chr 8:58,175,785...58,204,939
Ensembl chr 8:58,175,101...58,204,939
|
|
| G
|
Htr5b
|
5-hydroxytryptamine (serotonin) receptor 5B
|
affects expression
|
EXP
|
Nickel affects the expression of HTR5B mRNA
|
CTD |
PMID:18835401 |
|
NCBI chr13:35,239,662...35,252,586
Ensembl chr13:35,239,662...35,252,586
|
|
| G
|
Htra1
|
HtrA serine peptidase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HTRA1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 1:194,928,069...194,977,619
Ensembl chr 1:194,927,687...194,977,620
|
|
| G
|
Htra3
|
HtrA serine peptidase 3
|
increases expression
|
ISO
|
Nickel results in increased expression of HTRA3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:79,293,535...79,321,936
Ensembl chr14:79,293,541...79,321,936
|
|
| G
|
Hvcn1
|
hydrogen voltage-gated channel 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HVCN1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr12:40,001,205...40,030,671
Ensembl chr12:40,001,498...40,042,020
|
|
| G
|
Hyi
|
hydroxypyruvate isomerase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HYI mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:137,179,975...137,182,654
Ensembl chr 5:137,179,976...137,182,654
|
|
| G
|
Hykk
|
hydroxylysine kinase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HYKK mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:64,212,043...64,235,809
Ensembl chr 8:64,212,071...64,235,818
|
|
| G
|
Hyou1
|
hypoxia up-regulated 1
|
increases expression
|
ISO
|
Nickel results in increased expression of HYOU1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:53,602,882...53,614,998
Ensembl chr 8:53,602,604...53,614,997
|
|
| G
|
Ibsp
|
integrin-binding sialoprotein
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of IBSP mRNA trichostatin A inhibits the reaction [Nickel affects the expression of IBSP mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr14:5,744,497...5,757,242
Ensembl chr14:5,744,501...5,775,299
|
|
| G
|
Icam1
|
intercellular adhesion molecule 1
|
multiple interactions increases expression
|
ISO
|
[2-quinoxaline-carboxamide-N-adamantan-1-yl binds to and results in decreased activity of CASR protein] inhibits the reaction [Nickel results in increased expression of ICAM1 mRNA]; [Asbestos, Serpentine results in increased abundance of [Magnesium co-treated with Chromium co-treated with Nickel co-treated with Cobalt]] which results in increased expression of ICAM1 mRNA [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of ICAM1 mRNA; TNF protein promotes the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of ICAM1 mRNA] Nickel results in increased expression of ICAM1; Nickel results in increased expression of ICAM1 mRNA; Nickel results in increased expression of ICAM1 protein
|
CTD |
PMID:7864660 PMID:15715515 PMID:19781536 PMID:23195993 PMID:23503329 PMID:24768652 PMID:25583101 PMID:38605572 More...
|
|
NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617
|
|
| G
|
Icam2
|
intercellular adhesion molecule 2
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of ICAM2 mRNA Nickel results in increased expression of ICAM2 mRNA
|
CTD |
PMID:12540486 PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr10:91,808,449...91,819,319
Ensembl chr10:91,808,316...91,815,072
|
|
| G
|
Icos
|
inducible T-cell co-stimulator
|
increases expression
|
ISO
|
Nickel results in increased expression of ICOS mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr 9:69,862,042...69,900,864
Ensembl chr 9:69,877,785...69,900,960
|
|
| G
|
Id1
|
inhibitor of DNA binding 1
|
increases expression
|
ISO
|
Nickel results in increased expression of ID1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 3:161,671,525...161,672,691
Ensembl chr 3:161,671,538...161,672,685
|
|
| G
|
Id4
|
inhibitor of DNA binding 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ID4 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr17:16,595,724...16,598,293
Ensembl chr17:16,595,724...16,598,492
|
|
| G
|
Idh1
|
isocitrate dehydrogenase (NADP(+)) 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of IDH1 mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 9:74,027,887...74,057,442
Ensembl chr 9:74,027,892...74,049,555
|
|
| G
|
Idh3a
|
isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha
|
decreases expression
|
ISO
|
Nickel results in decreased expression of IDH3A mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:63,867,882...63,887,223
Ensembl chr 8:63,867,820...63,887,223
|
|
| G
|
Ido1
|
indoleamine 2,3-dioxygenase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of IDO1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr16:74,133,259...74,145,328
Ensembl chr16:74,133,259...74,145,328
|
|
| G
|
Ier3
|
immediate early response 3
|
increases expression
|
ISO
|
Nickel results in increased expression of IER3 mRNA
|
CTD |
PMID:18922574 |
|
NCBI chr20:2,933,173...2,934,377
Ensembl chr20:2,933,174...2,934,377
|
|
| G
|
Iffo2
|
intermediate filament family orphan 2
|
increases expression
|
ISO
|
Nickel results in increased expression of IFFO2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 5:157,114,089...157,160,135
Ensembl chr 5:157,114,089...157,160,135
|
|
| G
|
Ifi27
|
interferon, alpha-inducible protein 27
|
increases expression
|
ISO
|
Nickel results in increased expression of IFI27 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 6:128,355,312...128,361,783
Ensembl chr 6:128,355,079...128,361,781
|
|
| G
|
Ifi30
|
IFI30, lysosomal thiol reductase
|
increases expression
|
ISO
|
Nickel results in increased expression of IFI30 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr16:18,709,570...18,713,635
Ensembl chr16:18,709,563...18,715,711
|
|
| G
|
Ifi35
|
interferon-induced protein 35
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of IFI35 mRNA Nickel results in increased expression of IFI35 mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr10:86,881,270...86,889,523
Ensembl chr10:86,887,122...86,889,750
|
|
| G
|
Ifi44
|
interferon-induced protein 44
|
increases expression
|
ISO
|
Nickel results in increased expression of IFI44 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:243,286,050...243,303,869
Ensembl chr 2:243,286,052...243,306,877
|
|
| G
|
Ifi44l
|
interferon-induced protein 44-like
|
increases expression
|
ISO
|
Nickel results in increased expression of IFI44L mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:243,328,629...243,366,404
Ensembl chr 2:243,328,723...243,366,404
|
|
| G
|
Ifih1
|
interferon induced with helicase C domain 1
|
increases expression
|
ISO
|
Nickel results in increased expression of IFIH1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:67,635,924...67,683,968
Ensembl chr 3:67,637,545...67,683,968
|
|
| G
|
Ifit2
|
interferon-induced protein with tetratricopeptide repeats 2
|
increases expression
|
ISO
|
Nickel results in increased expression of IFIT2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 1:241,515,735...241,521,799
Ensembl chr 1:241,515,709...241,521,798
|
|
| G
|
Ifit3
|
interferon-induced protein with tetratricopeptide repeats 3
|
increases expression
|
ISO
|
Nickel results in increased expression of IFIT3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:241,527,326...241,532,469
Ensembl chr 1:241,526,880...241,532,521
|
|
| G
|
Ifitm1
|
interferon induced transmembrane protein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of IFITM1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:205,496,757...205,498,796
Ensembl chr 1:205,496,807...205,498,776
|
|
| G
|
Ifitm2
|
interferon induced transmembrane protein 2
|
increases expression
|
ISO
|
Nickel results in increased expression of IFITM2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:205,481,168...205,482,348
|
|
| G
|
Ifitm3
|
interferon induced transmembrane protein 3
|
increases expression
|
ISO
|
Nickel results in increased expression of IFITM3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:205,540,649...205,541,758
Ensembl chr 1:205,481,168...205,547,920
|
|
| G
|
Ifna1
|
interferon, alpha 1
|
increases expression
|
ISO
|
Nickel results in increased expression of IFNA1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 5:108,143,240...108,143,809
Ensembl chr 5:108,143,240...108,143,809
|
|
| G
|
Ifnar1
|
interferon alpha and beta receptor subunit 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of IFNAR1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr11:44,211,769...44,238,206
Ensembl chr11:44,211,845...44,238,205
|
|
| G
|
Ifnar2
|
interferon alpha and beta receptor subunit 2
|
increases expression
|
ISO
|
Nickel results in increased expression of IFNAR2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:44,099,574...44,131,941
Ensembl chr11:44,099,753...44,131,937
|
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| G
|
Ifng
|
interferon gamma
|
affects expression increases expression multiple interactions
|
ISO
|
Nickel affects the expression of IFNG mRNA Nickel results in increased expression of IFNG mRNA trichostatin A inhibits the reaction [Nickel affects the expression of IFNG mRNA]
|
CTD |
PMID:14575637 PMID:23195993 PMID:24768652 |
|
NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
|
|
| G
|
Ifrd2
|
interferon-related developmental regulator 2
|
increases expression
|
ISO
|
Nickel results in increased expression of IFRD2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:117,139,612...117,144,834
Ensembl chr 8:117,139,550...117,144,836
|
|
| G
|
Ift172
|
intraflagellar transport 172
|
decreases expression
|
ISO
|
Nickel results in decreased expression of IFT172 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 6:30,801,841...30,841,239
Ensembl chr 6:30,801,918...30,840,830
|
|
| G
|
Ift27
|
intraflagellar transport 27
|
affects expression decreases expression multiple interactions
|
ISO
|
Nickel affects the expression of IFT27 mRNA Nickel results in decreased expression of IFT27 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of IFT27 mRNA]
|
CTD |
PMID:14575637 PMID:24768652 |
|
NCBI chr 7:111,619,145...111,635,129
Ensembl chr 7:111,619,077...111,634,936
|
|
| G
|
Igdcc4
|
immunoglobulin superfamily, DCC subclass, member 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of IGDCC4 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 8:74,517,082...74,552,834
Ensembl chr 8:74,517,086...74,552,834
|
|
| G
|
Igf1
|
insulin-like growth factor 1
|
decreases response to substance decreases expression
|
ISO
|
Nickel results in decreased susceptibility to IGF1 protein Nickel results in decreased expression of IGF1 mRNA
|
CTD |
PMID:16485066 PMID:24768652 PMID:25583101 |
|
NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764
|
|
| G
|
Igf1r
|
insulin-like growth factor 1 receptor
|
decreases expression
|
ISO
|
Nickel results in decreased expression of IGF1R mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:130,959,997...131,248,664
|
|
| G
|
Igf2
|
insulin-like growth factor 2
|
decreases response to substance
|
ISO
|
Nickel results in decreased susceptibility to IGF2 protein
|
CTD |
PMID:16485066 |
|
NCBI chr 1:207,243,873...207,261,263
Ensembl chr 1:207,243,873...207,260,667
|
|
| G
|
Igfals
|
insulin-like growth factor binding protein, acid labile subunit
|
affects binding
|
ISO
|
IGFALS protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr10:14,397,076...14,408,439
Ensembl chr10:14,403,399...14,407,138
|
|
| G
|
Igfbp2
|
insulin-like growth factor binding protein 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of IGFBP2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 9:81,864,811...81,892,179
Ensembl chr 9:81,864,783...81,892,171
|
|
| G
|
Igfbp3
|
insulin-like growth factor binding protein 3
|
increases expression
|
ISO
|
Nickel results in increased expression of IGFBP3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr14:86,270,208...86,277,944
Ensembl chr14:86,270,208...86,277,944
|
|
| G
|
Igfbp6
|
insulin-like growth factor binding protein 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of IGFBP6 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 7:135,154,919...135,159,550
Ensembl chr 7:135,154,685...135,159,795
|
|
| G
|
Igflr1
|
IGF-like family receptor 1
|
increases expression
|
ISO
|
Nickel results in increased expression of IGFLR1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:94,945,866...94,948,476
Ensembl chr 1:94,945,967...94,948,473
|
|
| G
|
Igg-2a
|
gamma-2a immunoglobulin heavy chain
|
affects binding
|
ISO
|
IGHG4 protein binds to Nickel
|
CTD |
PMID:23896426 |
|
|
|
| G
|
Igsf10
|
immunoglobulin superfamily, member 10
|
decreases expression
|
ISO
|
Nickel results in decreased expression of IGSF10 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:145,725,868...145,754,850
Ensembl chr 2:145,725,878...145,754,579
|
|
| G
|
Igsf11
|
immunoglobulin superfamily, member 11
|
decreases expression
|
ISO
|
Nickel results in decreased expression of IGSF11 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr11:75,238,706...75,389,748
Ensembl chr11:75,236,545...75,390,425
|
|
| G
|
Igsf6
|
immunoglobulin superfamily, member 6
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of IGSF6 mRNA Nickel results in increased expression of IGSF6 mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 1:185,041,462...185,051,956
Ensembl chr 1:185,041,462...185,052,245
|
|
| G
|
Ikbip
|
IKBKB interacting protein
|
increases expression
|
ISO
|
Nickel results in increased expression of IKBIP mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:27,467,097...27,485,776
Ensembl chr 7:27,467,055...27,491,460
|
|
| G
|
Ikbke
|
inhibitor of nuclear factor kappa B kinase subunit epsilon
|
increases expression
|
ISO
|
Nickel results in increased expression of IKBKE mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:45,264,404...45,290,737
Ensembl chr13:45,264,412...45,289,396
|
|
| G
|
Ikzf1
|
IKAROS family zinc finger 1
|
increases expression
|
ISO
|
Nickel results in increased expression of IKZF1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:90,468,696...90,556,522
Ensembl chr14:90,469,172...90,557,574
|
|
| G
|
Ikzf3
|
IKAROS family zinc finger 3
|
increases expression
|
ISO
|
Nickel results in increased expression of IKZF3 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr10:83,956,850...84,049,861
Ensembl chr10:83,962,030...84,049,861
|
|
| G
|
Il10
|
interleukin 10
|
increases expression
|
ISO
|
Nickel results in increased expression of IL10 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
|
|
| G
|
Il10ra
|
interleukin 10 receptor subunit alpha
|
increases expression
|
ISO
|
Nickel results in increased expression of IL10RA mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:54,459,754...54,474,786
Ensembl chr 8:54,459,882...54,475,028
|
|
| G
|
Il10rb
|
interleukin 10 receptor subunit beta
|
decreases expression
|
ISO
|
Nickel results in decreased expression of IL10RB mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr11:44,132,471...44,154,062
Ensembl chr11:44,132,189...44,154,053
|
|
| G
|
Il11ra1
|
interleukin 11 receptor subunit alpha 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of IL11RA mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:61,727,650...61,737,265
Ensembl chr 5:61,727,931...61,737,264
|
|
| G
|
Il12b
|
interleukin 12B
|
increases expression
|
ISO
|
Nickel results in increased expression of IL12B mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194
|
|
| G
|
Il12rb1
|
interleukin 12 receptor subunit beta 1
|
increases expression
|
ISO
|
Nickel results in increased expression of IL12RB1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr16:18,654,207...18,668,887
Ensembl chr16:18,654,207...18,666,824
|
|
| G
|
Il12rb2
|
interleukin 12 receptor subunit beta 2
|
increases expression
|
ISO
|
Nickel results in increased expression of IL12RB2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:97,756,089...97,844,937
Ensembl chr 4:97,756,089...97,844,937
|
|
| G
|
Il13
|
interleukin 13
|
increases expression multiple interactions
|
ISO
|
Nickel results in increased expression of IL13 mRNA [TBX21 gene mutant form results in increased susceptibility to Nickel analog] which results in increased expression of IL13 protein
|
CTD |
PMID:24499286 PMID:24768652 PMID:25583101 |
|
NCBI chr10:38,290,926...38,293,483
Ensembl chr10:38,290,926...38,293,483
|
|
| G
|
Il13ra1
|
interleukin 13 receptor subunit alpha 1
|
increases expression
|
ISO
|
Nickel results in increased expression of IL13RA1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr X:120,213,670...120,294,777
Ensembl chr X:120,214,075...120,274,461
|
|
| G
|
Il13ra2
|
interleukin 13 receptor subunit alpha 2
|
increases expression
|
ISO
|
Nickel results in increased expression of IL13RA2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr X:115,814,620...115,886,080
Ensembl chr X:115,814,622...115,841,455
|
|
| G
|
Il15
|
interleukin 15
|
increases expression
|
ISO
|
Nickel results in increased expression of IL15 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr19:42,536,160...42,611,349
Ensembl chr19:42,545,346...42,611,348
|
|
| G
|
Il15ra
|
interleukin 15 receptor subunit alpha
|
increases expression
|
ISO
|
Nickel results in increased expression of IL15RA mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr17:71,712,141...71,742,072
Ensembl chr17:71,712,141...71,742,149
|
|
| G
|
Il16
|
interleukin 16
|
multiple interactions increases expression
|
ISO
|
Nickel results in increased expression of and results in increased secretion of IL16 protein Nickel results in increased expression of IL16 mRNA
|
CTD |
PMID:23624239 PMID:25583101 |
|
NCBI chr 1:147,026,852...147,127,177
Ensembl chr 1:147,027,097...147,127,023
|
|
| G
|
Il17a
|
interleukin 17A
|
increases expression
|
ISO
|
Nickel results in increased expression of IL17A mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:30,640,844...30,644,331
|
|
| G
|
Il17f
|
interleukin 17F
|
increases expression
|
ISO
|
Nickel results in increased expression of IL17F mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 9:30,686,532...30,697,918
Ensembl chr 9:30,686,538...30,697,918
|
|
| G
|
Il17ra
|
interleukin 17 receptor A
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of IL17RA mRNA Nickel results in increased expression of IL17RA mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 4:155,339,742...155,362,382
Ensembl chr 4:155,339,400...155,362,382
|
|
| G
|
Il17rd
|
interleukin 17 receptor D
|
decreases expression
|
ISO
|
Nickel results in decreased expression of IL17RD mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr16:2,235,172...2,489,827
Ensembl chr16:2,235,169...2,301,850
|
|
| G
|
Il18
|
interleukin 18
|
multiple interactions increases expression decreases expression
|
EXP ISO
|
[Nickel co-treated with Cobalt co-treated with Tungsten] results in decreased expression of IL18 mRNA Nickel results in increased expression of IL18 mRNA [SELENOM protein affects the susceptibility to Nickel] which affects the expression of IL18 mRNA; Melatonin affects the reaction [[SELENOM protein affects the susceptibility to Nickel] which affects the expression of IL18 mRNA]; Melatonin inhibits the reaction [Nickel results in increased expression of IL18 mRNA] Nickel results in decreased expression of IL18 mRNA
|
CTD |
PMID:22198552 PMID:24768652 PMID:36504304 |
|
NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286
|
|
| G
|
Il18bp
|
interleukin 18 binding protein
|
increases expression
|
ISO
|
Nickel results in increased expression of IL18BP mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:165,784,916...165,787,990
Ensembl chr 1:165,784,069...165,786,955
|
|
| G
|
Il18r1
|
interleukin 18 receptor 1
|
increases expression
|
ISO
|
Nickel results in increased expression of IL18R1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:50,223,274...50,257,370
Ensembl chr 9:50,223,200...50,257,367
|
|
| G
|
Il18rap
|
interleukin 18 receptor accessory protein
|
increases expression
|
ISO
|
Nickel results in increased expression of IL18RAP mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 9:50,263,723...50,296,583
Ensembl chr 9:50,263,733...50,296,583
|
|
| G
|
Il19
|
interleukin 19
|
increases expression
|
ISO
|
Nickel results in increased expression of IL19 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:44,949,989...44,958,714
Ensembl chr13:44,949,989...44,958,714
|
|
| G
|
Il1a
|
interleukin 1 alpha
|
increases expression
|
ISO
|
Nickel results in increased expression of IL1A mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013
|
|
| G
|
Il1b
|
interleukin 1 beta
|
multiple interactions increases expression
|
ISO EXP
|
3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of IL1B protein]; [2-quinoxaline-carboxamide-N-adamantan-1-yl binds to and results in decreased activity of CASR protein] inhibits the reaction [Nickel results in increased expression of IL1B mRNA]; [Asbestos, Serpentine results in increased abundance of [Magnesium co-treated with Chromium co-treated with Nickel co-treated with Cobalt]] which results in increased expression of IL1B mRNA; [Asbestos, Serpentine results in increased abundance of [Magnesium co-treated with Chromium co-treated with Nickel co-treated with Cobalt]] which results in increased secretion of IL1B protein; [nickel chloride results in increased abundance of Nickel] which results in increased expression of IL1B protein; Resveratrol inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of IL1B protein] [Nickel co-treated with IL1B protein] results in increased expression of NOS2 mRNA; [SELENOM protein affects the susceptibility to Nickel] which affects the expression of IL1B mRNA; IL1B protein promotes the reaction [Nickel results in increased abundance of Nitric Oxide]; Melatonin affects the reaction [[SELENOM protein affects the susceptibility to Nickel] which affects the expression of IL1B mRNA]; Melatonin affects the reaction [Nickel affects the reaction [SELENOM protein affects the expression of IL1B protein]]; Melatonin inhibits the reaction [Nickel results in increased expression of IL1B mRNA]; Nickel affects the reaction [Melatonin affects the reaction [SELENOM protein affects the expression of IL1B protein]]; Nickel affects the reaction [SELENOM protein affects the expression of IL1B protein]; Nickel inhibits the reaction [Melatonin results in decreased expression of IL1B mRNA]; Nickel inhibits the reaction [Melatonin results in decreased expression of IL1B protein] Nickel results in increased expression of IL1B mRNA; Nickel results in increased expression of IL1B protein [[nickel chloride results in increased abundance of Nickel] co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] results in increased expression of IL1B protein; [nickel chloride results in increased abundance of Nickel] which results in increased expression of IL1B protein; [Nickel co-treated with Cobalt co-treated with Tungsten] results in increased expression of IL1B mRNA; [Nickel co-treated with Cobalt co-treated with Tungsten] results in increased expression of IL1B protein; [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of IL1B mRNA; [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of IL1B protein; Fatty Acids, Omega-3 inhibits the reaction [[[nickel chloride results in increased abundance of Nickel] co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] results in increased expression of IL1B protein]
|
CTD |
PMID:11919079 PMID:19781536 PMID:22198552 PMID:23195993 PMID:23788631 PMID:24768652 PMID:25583101 PMID:31639282 PMID:31943712 PMID:36504304 PMID:38605572 More...
|
|
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
|
|
| G
|
Il1r2
|
interleukin 1 receptor type 2
|
increases expression
|
ISO
|
Nickel results in increased expression of IL1R2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 9:49,879,928...49,920,374
Ensembl chr 9:49,877,266...49,920,374
|
|
| G
|
Il1rap
|
interleukin 1 receptor accessory protein
|
increases expression
|
ISO
|
Nickel results in increased expression of IL1RAP mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr11:87,567,813...87,704,346
Ensembl chr11:87,575,116...87,704,342
|
|
| G
|
Il1rl1
|
interleukin 1 receptor-like 1
|
increases expression
|
ISO
|
Nickel results in increased expression of IL1RL1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:50,157,326...50,222,888
Ensembl chr 9:50,204,551...50,222,891
|
|
| G
|
Il1rn
|
interleukin 1 receptor antagonist
|
increases expression
|
ISO
|
Nickel results in increased expression of IL1RN mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:27,509,798...27,525,732
|
|
| G
|
Il2
|
interleukin 2
|
increases expression
|
ISO
|
Nickel results in increased expression of IL2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672
|
|
| G
|
Il20ra
|
interleukin 20 receptor subunit alpha
|
decreases expression
|
ISO
|
Nickel results in decreased expression of IL20RA mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:16,243,683...16,313,229
Ensembl chr 1:16,243,801...16,313,221
|
|
| G
|
Il21r
|
interleukin 21 receptor
|
increases expression
|
ISO
|
Nickel results in increased expression of IL21R mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:189,598,682...189,626,340
Ensembl chr 1:189,598,558...189,626,342
|
|
| G
|
Il22
|
interleukin 22
|
increases expression
|
ISO
|
Nickel results in increased expression of IL22 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:55,687,061...55,691,526
Ensembl chr 7:55,686,896...55,692,201
|
|
| G
|
Il22ra2
|
interleukin 22 receptor subunit alpha 2
|
increases expression
|
ISO
|
Nickel results in increased expression of IL22RA2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:16,172,238...16,228,009
Ensembl chr 1:16,184,113...16,197,950
|
|
| G
|
Il23a
|
interleukin 23 subunit alpha
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increases expression
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ISO
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Nickel results in increased expression of IL23A mRNA
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CTD |
PMID:23195993 PMID:24768652 |
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NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:1,306,320...1,308,434
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| G
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Il24
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interleukin 24
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increases expression
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ISO
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Nickel results in increased expression of IL24 mRNA
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CTD |
PMID:25583101 |
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NCBI chr13:44,905,362...44,910,760
Ensembl chr13:44,905,363...44,910,760
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| G
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Il27ra
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interleukin 27 receptor subunit alpha
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increases expression
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ISO
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Nickel results in increased expression of IL27RA mRNA
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CTD |
PMID:25583101 |
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NCBI chr19:41,014,730...41,026,740
Ensembl chr19:41,014,730...41,026,760
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| G
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Il2ra
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interleukin 2 receptor subunit alpha
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affects expression increases expression multiple interactions
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ISO
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Nickel affects the expression of IL2RA mRNA Nickel results in increased expression of IL2RA mRNA trichostatin A inhibits the reaction [Nickel affects the expression of IL2RA mRNA]
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CTD |
PMID:14575637 PMID:24768652 PMID:25583101 |
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NCBI chr17:71,759,802...71,808,475
Ensembl chr17:71,759,802...71,808,507
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| G
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Il2rb
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interleukin 2 receptor subunit beta
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increases expression
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ISO
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Nickel results in increased expression of IL2RB mRNA
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CTD |
PMID:25583101 |
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NCBI chr 7:111,913,828...111,928,537
Ensembl chr 7:111,913,828...111,928,537
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| G
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Il2rg
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interleukin 2 receptor subunit gamma
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increases expression
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ISO
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Nickel results in increased expression of IL2RG mRNA
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CTD |
PMID:25583101 |
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NCBI chr X:70,435,340...70,439,052
Ensembl chr X:70,435,343...70,439,161
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| G
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Il31
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interleukin 31
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increases expression
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ISO
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Nickel results in increased expression of IL31 mRNA
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CTD |
PMID:24768652 |
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NCBI chr12:38,756,231...38,765,917
Ensembl chr12:38,762,870...38,765,921
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| G
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Il33
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interleukin 33
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decreases expression
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ISO
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Nickel results in decreased expression of IL33 mRNA
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CTD |
PMID:24768652 |
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NCBI chr 1:237,115,478...237,149,897
Ensembl chr 1:237,115,572...237,150,901
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| G
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Il34
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interleukin 34
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decreases expression
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ISO
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Nickel results in decreased expression of IL34 mRNA
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CTD |
PMID:24768652 PMID:25583101 |
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NCBI chr19:55,624,368...55,690,576
Ensembl chr19:55,624,369...55,673,376
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| G
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Il36g
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interleukin 36, gamma
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increases expression
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ISO
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Nickel results in increased expression of IL36G mRNA
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CTD |
PMID:25583101 |
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NCBI chr 3:27,346,675...27,352,839
Ensembl chr 3:27,346,670...27,352,834
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| G
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Il36rn
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interleukin 36 receptor antagonist
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affects expression multiple interactions
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ISO
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Nickel affects the expression of IL36RN mRNA trichostatin A inhibits the reaction [Nickel affects the expression of IL36RN mRNA]
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CTD |
PMID:14575637 |
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NCBI chr 3:27,442,679...27,449,306
Ensembl chr 3:27,442,709...27,449,306
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| G
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Il4
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interleukin 4
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increases expression
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ISO
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Nickel results in increased expression of IL4 mRNA
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CTD |
PMID:24768652 |
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NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549
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| G
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Il4i1
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interleukin 4 induced 1
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increases expression
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ISO
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Nickel results in increased expression of IL4I1 mRNA
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CTD |
PMID:25583101 |
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NCBI chr 1:104,435,540...104,461,049
Ensembl chr 1:104,435,981...104,461,053
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| G
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Il4r
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interleukin 4 receptor
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increases expression
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ISO
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Nickel results in increased expression of IL4RA mRNA Nickel results in increased expression of IL4R mRNA
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CTD |
PMID:12540486 PMID:24768652 PMID:25583101 |
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NCBI chr 1:189,545,739...189,570,639
Ensembl chr 1:189,544,988...189,570,636
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| G
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Il5
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interleukin 5
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increases secretion increases expression
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ISO
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Nickel results in increased secretion of IL5 protein Nickel results in increased expression of IL5 mRNA
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CTD |
PMID:15059101 PMID:24768652 PMID:25583101 |
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NCBI chr10:38,375,132...38,378,003
Ensembl chr10:38,375,132...38,378,003
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| G
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Il6
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interleukin 6
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increases expression multiple interactions
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ISO EXP
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Nickel results in increased expression of IL6 protein Nickel results in increased expression of IL6 mRNA 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide inhibits the reaction [[Nickel co-treated with lipopolysaccharide, E. coli O26-B6] results in increased expression of IL6 mRNA]; 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide inhibits the reaction [[Nickel co-treated with lipopolysaccharide, E. coli O26-B6] results in increased secretion of IL6 protein]; [Asbestos, Serpentine results in increased abundance of [Magnesium co-treated with Chromium co-treated with Nickel co-treated with Cobalt]] which results in increased expression of IL6 mRNA; [nickel chloride results in increased abundance of Nickel] which results in increased expression of IL6 mRNA; [Nickel co-treated with lipopolysaccharide, E. coli O26-B6] results in increased expression of IL6 mRNA; [Nickel co-treated with lipopolysaccharide, E. coli O26-B6] results in increased secretion of IL6 protein; [Nickel co-treated with Lipopolysaccharides] results in increased secretion of IL6 protein; N'-(7-fluoroH-pyrrolo(1,2-a)quinoxalin-4-yl)pyrazine-2-carbohydrazide promotes the reaction [[Nickel co-treated with lipopolysaccharide, E. coli O26-B6] results in increased expression of IL6 mRNA]; N'-(7-fluoroH-pyrrolo(1,2-a)quinoxalin-4-yl)pyrazine-2-carbohydrazide promotes the reaction [[Nickel co-treated with lipopolysaccharide, E. coli O26-B6] results in increased secretion of IL6 protein]; Resveratrol inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of IL6 mRNA] [Zinc co-treated with Nickel co-treated with Cobalt] affects the reaction [Dietary Fats affects the expression of IL6 mRNA] [Nickel co-treated with Cobalt co-treated with Tungsten] results in increased expression of IL6 mRNA; [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of IL6 mRNA
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CTD |
PMID:11919079 PMID:22198552 PMID:22287454 PMID:23195993 PMID:23503329 PMID:24768652 PMID:25583101 PMID:31943712 PMID:35623502 PMID:38605572 More...
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NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
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| G
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Il6r
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interleukin 6 receptor
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decreases expression increases expression
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ISO
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Nickel results in decreased expression of IL6R mRNA Nickel results in increased expression of IL6R mRNA
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CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
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NCBI chr 2:177,582,020...177,646,705
Ensembl chr 2:177,582,164...177,645,221
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| G
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Il6st
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interleukin 6 cytokine family signal transducer
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decreases expression
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ISO
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Nickel results in decreased expression of IL6ST mRNA
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CTD |
PMID:25583101 |
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NCBI chr 2:45,798,872...45,839,501
Ensembl chr 2:45,799,380...45,843,182
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| G
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Il7
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interleukin 7
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increases expression
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ISO
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Nickel results in increased expression of IL7 mRNA
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CTD |
PMID:24768652 |
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NCBI chr 2:96,142,523...96,186,282
Ensembl chr 2:96,142,092...96,187,389
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| G
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Il7r
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interleukin 7 receptor
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increases expression
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ISO
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Nickel results in increased expression of IL7R mRNA
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CTD |
PMID:24768652 PMID:25583101 |
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NCBI chr 2:60,179,561...60,204,937
Ensembl chr 2:60,181,382...60,211,027
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| G
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Il9
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interleukin 9
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increases expression
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ISO
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Nickel results in increased expression of IL9 mRNA
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CTD |
PMID:24768652 PMID:25583101 |
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NCBI chr17:8,117,028...8,120,151
Ensembl chr17:8,117,028...8,120,151
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| G
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Ilf3
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interleukin enhancer binding factor 3
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increases expression
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ISO
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Nickel results in increased expression of ILF3 mRNA
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CTD |
PMID:25583101 |
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NCBI chr 8:28,198,454...28,236,634
Ensembl chr 8:28,198,543...28,236,612
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| G
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Ina
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internexin neuronal intermediate filament protein, alpha
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increases expression
|
ISO
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Nickel results in increased expression of INA mRNA
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CTD |
PMID:25583101 |
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NCBI chr 1:255,838,129...255,849,680
Ensembl chr 1:255,838,129...255,849,680
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| G
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Inhbb
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inhibin subunit beta B
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multiple interactions decreases expression affects expression
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ISO
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trichostatin A inhibits the reaction [Nickel affects the expression of INHBB mRNA] Nickel results in decreased expression of INHBB mRNA
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CTD |
PMID:14575637 PMID:24768652 PMID:25583101 |
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NCBI chr13:33,083,671...33,089,373
Ensembl chr13:33,083,671...33,089,609
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| G
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Inip
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INTS3 and NABP interacting protein
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decreases expression
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ISO
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Nickel results in decreased expression of INIP mRNA
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CTD |
PMID:23195993 |
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NCBI chr 5:79,443,317...79,457,552
Ensembl chr 5:79,443,317...79,457,552
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| G
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Inmt
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indolethylamine N-methyltransferase
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decreases expression
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ISO
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Nickel results in decreased expression of INMT mRNA
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CTD |
PMID:24768652 PMID:25583101 |
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NCBI chr 4:85,648,459...85,652,755
Ensembl chr 4:85,648,459...85,652,755
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| G
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Inpp4a
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inositol polyphosphate-4-phosphatase type I A
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increases expression
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ISO
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Nickel results in increased expression of INPP4A mRNA
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CTD |
PMID:24768652 |
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NCBI chr 9:47,024,064...47,142,391
Ensembl chr 9:47,087,471...47,135,968
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| G
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Inpp5b
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inositol polyphosphate-5-phosphatase B
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decreases expression
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ISO
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Nickel results in decreased expression of INPP5B mRNA
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CTD |
PMID:23195993 |
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NCBI chr 5:142,281,454...142,345,993
Ensembl chr 5:142,281,418...142,345,991
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| G
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Inpp5d
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inositol polyphosphate-5-phosphatase D
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increases expression
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ISO
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Nickel results in increased expression of INPP5D mRNA
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CTD |
PMID:24768652 PMID:25583101 |
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NCBI chr 9:95,735,533...95,840,584
Ensembl chr 9:95,735,530...95,840,589
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| G
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Ins1
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insulin 1
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multiple interactions
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EXP ISO
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[Nickel co-treated with INS1 protein] results in increased phosphorylation of INSR protein; [Nickel co-treated with INS1 protein] results in increased phosphorylation of IRS4 protein [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CCL2 mRNA; [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CCL20 mRNA; [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CCL5 mRNA; [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CCL7 mRNA; [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CCL8 mRNA; [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CCL9 mRNA; [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CX3CL1 mRNA; [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CXCL11 mRNA; [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CXCL16 mRNA; [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CXCL2 mRNA; [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CXCL5 mRNA; [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CXCL9 mRNA; [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of ICAM1 mRNA; [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of MMP13 mRNA; [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of MMP1A mRNA; [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of MMP9 mRNA; [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of VCAM1 mRNA; [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CCL17 mRNA; [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CCL19 mRNA; [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CCL24 mRNA; [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CCL25 mRNA; [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CCL27 mRNA; [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CKLF mRNA; [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CXCL1 mRNA; [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CXCL10 mRNA; [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CXCL12 mRNA; [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of MMP3 mRNA; [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PF4 mRNA; TNF protein inhibits the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CCL17 mRNA]; TNF protein inhibits the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CCL19 mRNA]; TNF protein inhibits the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CXCL1 mRNA]; TNF protein inhibits the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CXCL10 mRNA]; TNF protein inhibits the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CXCL12 mRNA]; TNF protein inhibits the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of MMP3 mRNA]; TNF protein inhibits the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PF4 mRNA]; TNF protein promotes the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CCL2 mRNA]; TNF protein promotes the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CCL20 mRNA]; TNF protein promotes the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CCL7 mRNA]; TNF protein promotes the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CCL8 mRNA]; TNF protein promotes the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CCL9 mRNA]; TNF protein promotes the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CX3CL1 mRNA]; TNF protein promotes the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CXCL16 mRNA]; TNF protein promotes the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CXCL2 mRNA]; TNF protein promotes the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CXCL5 mRNA]; TNF protein promotes the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CXCL9 mRNA]; TNF protein promotes the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of ICAM1 mRNA]; TNF protein promotes the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of MMP13 mRNA]; TNF protein promotes the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of MMP1A mRNA]; TNF protein promotes the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of MMP9 mRNA]; TNF protein promotes the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of VCAM1 mRNA]
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CTD |
PMID:1321133 PMID:23503329 |
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NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682
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| G
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Insig1
|
insulin induced gene 1
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increases expression decreases expression
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ISO
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Nickel results in increased expression of INSIG1 mRNA Nickel results in decreased expression of INSIG1 mRNA
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CTD |
PMID:23195993 PMID:24768652 |
|
NCBI chr 4:8,049,339...8,057,812
Ensembl chr 4:8,049,556...8,057,778
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| G
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Insr
|
insulin receptor
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multiple interactions decreases expression
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EXP ISO
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[Nickel co-treated with INS1 protein] results in increased phosphorylation of INSR protein Nickel results in decreased expression of INSR mRNA
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CTD |
PMID:1321133 PMID:24768652 |
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NCBI chr12:5,991,135...6,129,275
Ensembl chr12:5,981,835...6,128,803
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| G
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Ints7
|
integrator complex subunit 7
|
decreases expression
|
ISO
|
Nickel results in decreased expression of INTS7 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr13:105,686,208...105,739,609
Ensembl chr13:105,686,128...105,739,608
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| G
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Intu
|
inturned planar cell polarity protein
|
decreases expression
|
ISO
|
Nickel results in decreased expression of INTU mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:125,528,965...125,613,295
Ensembl chr 2:125,529,208...125,613,295
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| G
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Ipcef1
|
interaction protein for cytohesin exchange factors 1
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increases expression
|
ISO
|
Nickel results in increased expression of IPCEF1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:45,654,252...45,857,045
Ensembl chr 1:45,662,818...45,856,993
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| G
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Ipo4
|
importin 4
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multiple interactions increases expression
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ISO
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MT1 affects the reaction [Nickel affects the expression of IPO4 mRNA]; MT2 affects the reaction [Nickel affects the expression of IPO4 mRNA] Nickel results in increased expression of IPO4 mRNA
|
CTD |
PMID:16166738 PMID:24768652 PMID:25583101 |
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NCBI chr15:33,087,321...33,097,241
Ensembl chr15:33,087,321...33,097,241
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|
| G
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Ipo8
|
importin 8
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decreases expression
|
ISO
|
Nickel results in decreased expression of IPO8 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 4:183,460,583...183,529,259
Ensembl chr 4:183,460,583...183,524,519
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| G
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Ipp
|
intracisternal A particle-promoted polypeptide
|
decreases expression
|
ISO
|
Nickel results in decreased expression of IPP mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:135,199,198...135,237,912
Ensembl chr 5:135,180,109...135,238,000
|
|
| G
|
Irag1
|
inositol 1,4,5-triphosphate receptor associated 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of IRAG1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:174,416,383...174,528,913
Ensembl chr 1:174,416,385...174,528,851
|
|
| G
|
Irag2
|
inositol 1,4,5-triphosphate receptor associated 2
|
increases expression
|
ISO
|
Nickel results in increased expression of IRAG2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:179,819,526...179,874,408
Ensembl chr 4:179,820,188...179,874,406
|
|
| G
|
Irak2
|
interleukin-1 receptor-associated kinase 2
|
increases expression
|
ISO
|
Nickel results in increased expression of IRAK2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 4:148,341,704...148,398,211
Ensembl chr 4:148,341,719...148,398,210
|
|
| G
|
Irf1
|
interferon regulatory factor 1
|
increases expression
|
ISO
|
Nickel results in increased expression of IRF1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:38,417,935...38,424,946
Ensembl chr10:38,417,148...38,424,947
|
|
| G
|
Irf2
|
interferon regulatory factor 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of IRF2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr16:52,171,855...52,283,620
Ensembl chr16:52,164,442...52,282,627
|
|
| G
|
Irf4
|
interferon regulatory factor 4
|
increases expression
|
ISO
|
Nickel results in increased expression of IRF4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr17:33,930,460...33,948,842
Ensembl chr17:33,930,471...33,948,730
|
|
| G
|
Irf5
|
interferon regulatory factor 5
|
increases expression
|
ISO
|
Nickel results in increased expression of IRF5 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:59,092,914...59,104,596
Ensembl chr 4:59,081,357...59,112,552
|
|
| G
|
Irf7
|
interferon regulatory factor 7
|
increases expression
|
ISO
|
Nickel results in increased expression of IRF7 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:205,796,956...205,800,543
Ensembl chr 1:205,796,959...205,800,023
|
|
| G
|
Irf8
|
interferon regulatory factor 8
|
increases expression
|
ISO
|
Nickel results in increased expression of IRF8 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr19:65,699,284...65,721,066
Ensembl chr19:65,699,284...65,721,062
|
|
| G
|
Irf9
|
interferon regulatory factor 9
|
increases expression
|
ISO
|
Nickel results in increased expression of IRF9 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr15:33,065,422...33,071,881
Ensembl chr15:33,065,659...33,071,879
|
|
| G
|
Irs1
|
insulin receptor substrate 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of IRS1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:90,993,519...91,054,538
|
|
| G
|
Irs2
|
insulin receptor substrate 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of IRS2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr16:85,190,310...85,214,543
Ensembl chr16:85,190,111...85,214,543
|
|
| G
|
Irs4
|
insulin receptor substrate 4
|
multiple interactions
|
EXP
|
[Nickel co-treated with INS1 protein] results in increased phosphorylation of IRS4 protein
|
CTD |
PMID:1321133 |
|
NCBI chr X:110,132,490...110,148,473
Ensembl chr X:110,132,405...110,149,088
|
|
| G
|
Irx1
|
iroquois homeobox 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of IRX1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 1:33,123,122...33,128,951
Ensembl chr 1:33,123,122...33,128,951
|
|
| G
|
Irx5
|
iroquois homeobox 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of IRX5 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr19:30,812,033...30,816,885
Ensembl chr19:30,797,202...30,815,029
|
|
| G
|
Isg15
|
ISG15 ubiquitin-like modifier
|
increases expression
|
ISO
|
Nickel results in increased expression of ISG15 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:172,066,369...172,067,656
Ensembl chr 5:172,066,369...172,067,656
|
|
| G
|
Isg20
|
interferon stimulated exonuclease gene 20
|
increases expression
|
ISO
|
Nickel results in increased expression of ISG20 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:142,234,729...142,246,403
Ensembl chr 1:142,236,137...142,246,401
|
|
| G
|
Isg20l2
|
interferon stimulated exonuclease gene 20-like 2
|
increases expression
|
ISO
|
Nickel results in increased expression of ISG20L2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:175,694,638...175,704,125
Ensembl chr 2:175,695,615...175,705,095
|
|
| G
|
Ist1
|
IST1 factor associated with ESCRT-III
|
decreases expression
|
ISO
|
Nickel results in decreased expression of IST1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr19:54,558,353...54,580,551
Ensembl chr19:54,558,353...54,580,491
|
|
| G
|
Isyna1
|
inositol-3-phosphate synthase 1
|
increases expression decreases expression
|
ISO
|
Nickel results in increased expression of ISYNA1 mRNA Nickel results in decreased expression of ISYNA1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr16:18,873,119...18,876,116
Ensembl chr16:18,873,121...18,875,955
|
|
| G
|
Itga4
|
integrin subunit alpha 4
|
increases expression
|
ISO
|
Nickel results in increased expression of ITGA4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:84,569,487...84,646,276
Ensembl chr 3:84,560,369...84,641,039
|
|
| G
|
Itga7
|
integrin subunit alpha 7
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ITGA7 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:1,944,447...1,973,347
Ensembl chr 7:1,944,460...1,973,339
|
|
| G
|
Itga8
|
integrin subunit alpha 8
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ITGA8 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr17:80,213,139...80,410,633
Ensembl chr17:80,213,143...80,410,633
|
|
| G
|
Itgal
|
integrin subunit alpha L
|
multiple interactions increases expression affects expression
|
ISO
|
trichostatin A inhibits the reaction [Nickel affects the expression of ITGAL mRNA] Nickel results in increased expression of ITGAL mRNA
|
CTD |
PMID:14575637 PMID:25583101 |
|
NCBI chr 1:191,348,424...191,386,228
Ensembl chr 1:191,348,542...191,386,225
|
|
| G
|
Itgam
|
integrin subunit alpha M
|
increases expression
|
ISO
|
Nickel results in increased expression of ITGAM mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:192,089,496...192,139,947
Ensembl chr 1:192,089,542...192,139,943
|
|
| G
|
Itgax
|
integrin subunit alpha X
|
increases expression
|
ISO
|
Nickel results in increased expression of ITGAX mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:192,140,089...192,171,151
Ensembl chr 1:192,149,905...192,171,151
|
|
| G
|
Itgb2
|
integrin subunit beta 2
|
increases expression
|
ISO
|
Nickel results in increased expression of ITGB2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr20:11,061,009...11,097,242
Ensembl chr20:11,058,492...11,097,182
|
|
| G
|
Itgb3
|
integrin subunit beta 3
|
increases expression
|
ISO
|
Nickel results in increased expression of ITGB3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:90,009,927...90,067,787
Ensembl chr10:90,009,900...90,067,800
|
|
| G
|
Itgb5
|
integrin subunit beta 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ITGB5 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr11:80,333,588...80,449,373
Ensembl chr11:80,333,590...80,449,373
|
|
| G
|
Itgb6
|
integrin subunit beta 6
|
increases expression
|
ISO
|
Nickel results in increased expression of ITGB6 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:65,454,964...65,579,179
Ensembl chr 3:65,456,713...65,530,333
|
|
| G
|
Itgb7
|
integrin subunit beta 7
|
increases expression
|
ISO
|
Nickel results in increased expression of ITGB7 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:135,225,962...135,243,522
Ensembl chr 7:135,226,555...135,243,597
|
|
| G
|
Itgbl1
|
integrin subunit beta like 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ITGBL1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr15:107,186,792...107,448,335
Ensembl chr15:107,186,689...107,451,098
|
|
| G
|
Itih1
|
inter-alpha trypsin inhibitor, heavy chain 1
|
affects binding
|
ISO
|
ITIH1 protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr16:6,128,696...6,142,813
Ensembl chr16:6,128,698...6,142,853
|
|
| G
|
Itih2
|
inter-alpha-trypsin inhibitor heavy chain 2
|
affects binding
|
ISO
|
ITIH2 protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr17:73,285,281...73,321,555
Ensembl chr17:73,285,270...73,321,547
|
|
| G
|
Itih3
|
inter-alpha trypsin inhibitor, heavy chain 3
|
affects binding
|
ISO
|
ITIH3 protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr16:6,108,378...6,123,609
Ensembl chr16:6,108,382...6,123,374
|
|
| G
|
Itih4
|
inter-alpha-trypsin inhibitor heavy chain 4
|
affects binding
|
ISO
|
ITIH4 protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr16:6,086,985...6,102,162
Ensembl chr16:6,086,973...6,102,160
|
|
| G
|
Itih5
|
inter-alpha-trypsin inhibitor heavy chain 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ITIH5 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr17:73,161,886...73,261,930
Ensembl chr17:73,161,611...73,262,496
|
|
| G
|
Itk
|
IL2-inducible T-cell kinase
|
increases expression
|
ISO
|
Nickel results in increased expression of ITK mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:31,254,667...31,316,004
Ensembl chr10:31,254,667...31,316,004
|
|
| G
|
Itm2a
|
integral membrane protein 2A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ITM2A mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr X:76,559,183...76,565,144
Ensembl chr X:76,559,181...76,565,437
|
|
| G
|
Itpr1
|
inositol 1,4,5-trisphosphate receptor, type 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ITPR1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:142,743,401...143,066,505
Ensembl chr 4:142,743,334...143,066,504
|
|
| G
|
Itprid1
|
ITPR interacting domain containing 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ITPRID1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:86,345,467...86,505,820
Ensembl chr 4:86,345,724...86,505,818
|
|
| G
|
Itsn1
|
intersectin 1
|
increases expression
|
ISO
|
Nickel results in increased expression of ITSN1 mRNA
|
CTD |
PMID:18922574 |
|
NCBI chr11:44,464,515...44,646,598
Ensembl chr11:44,513,186...44,646,598
|
|
| G
|
Ivl
|
involucrin
|
increases expression
|
ISO
|
Nickel results in increased expression of IVL mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:180,842,307...180,854,646
Ensembl chr 2:180,842,307...180,846,578
|
|
| G
|
Jade1
|
jade family PHD finger 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of JADE1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:126,471,124...126,524,252
Ensembl chr 2:126,471,124...126,524,252
|
|
| G
|
Jag2
|
jagged canonical Notch ligand 2
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of JAG2 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of JAG2 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 6:137,804,133...137,826,738
Ensembl chr 6:137,804,133...137,826,738
|
|
| G
|
Jak2
|
Janus kinase 2
|
multiple interactions increases expression decreases expression affects expression
|
ISO
|
trichostatin A inhibits the reaction [Nickel affects the expression of JAK2 mRNA] Nickel results in increased expression of JAK2 mRNA Nickel results in decreased expression of JAK2 mRNA
|
CTD |
PMID:14575637 PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762
|
|
| G
|
Jak3
|
Janus kinase 3
|
increases expression
|
ISO
|
Nickel results in increased expression of JAK3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr16:18,418,807...18,432,515
Ensembl chr16:18,420,415...18,433,222
|
|
| G
|
Jam2
|
junctional adhesion molecule 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of JAM2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr11:37,316,287...37,366,517
Ensembl chr11:37,317,511...37,367,510
|
|
| G
|
Jaml
|
junction adhesion molecule like
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of JAML mRNA Nickel results in increased expression of JAML mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr 8:54,281,596...54,313,655
Ensembl chr 8:54,281,644...54,313,500
|
|
| G
|
Jcad
|
junctional cadherin 5 associated
|
decreases expression
|
ISO
|
Nickel results in decreased expression of JCAD mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr17:57,784,634...57,826,213
Ensembl chr17:57,784,634...57,826,183
|
|
| G
|
Jchain
|
joining chain of multimeric IgA and IgM
|
affects binding decreases expression increases expression
|
ISO
|
JCHAIN protein binds to Nickel Nickel results in decreased expression of JCHAIN mRNA Nickel results in increased expression of JCHAIN mRNA
|
CTD |
PMID:23195993 PMID:23896426 PMID:25583101 |
|
NCBI chr14:19,822,976...19,831,072
Ensembl chr14:19,822,976...19,838,307
|
|
| G
|
Jmy
|
junction mediating and regulatory protein, p53 cofactor
|
increases expression
|
ISO
|
Nickel results in increased expression of JMY mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 2:26,401,047...26,465,959
Ensembl chr 2:26,409,969...26,465,649
|
|
| G
|
Josd1
|
Josephin domain containing 1
|
increases expression
|
ISO
|
Nickel results in increased expression of JOSD1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 7:113,110,709...113,124,632
Ensembl chr 7:113,110,717...113,124,632
|
|
| G
|
Jph2
|
junctophilin 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of JPH2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:172,414,246...172,478,678
Ensembl chr 3:172,414,256...172,478,348
|
|
| G
|
Jpt1
|
Jupiter microtubule associated homolog 1
|
increases expression
|
ISO
|
Nickel results in increased expression of JPT1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:101,243,428...101,261,464
Ensembl chr10:101,243,424...101,261,469
|
|
| G
|
Jun
|
Jun proto-oncogene, AP-1 transcription factor subunit
|
increases expression multiple interactions
|
ISO
|
Nickel results in increased expression of JUN mRNA [Copper co-treated with Lead co-treated with Cadmium co-treated with Zinc co-treated with Mercury co-treated with Chromium co-treated with Manganese co-treated with Nickel] results in increased expression of JUN protein
|
CTD |
PMID:23195993 PMID:28035397 |
|
NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285
|
|
| G
|
Jund
|
JunD proto-oncogene, AP-1 transcription factor subunit
|
increases expression
|
ISO
|
Nickel results in increased expression of JUND mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr16:18,768,093...18,769,771
Ensembl chr16:18,764,985...18,782,148
|
|
| G
|
Kalrn
|
kalirin, RhoGEF kinase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KALRN mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr11:79,703,345...80,309,210
Ensembl chr11:79,703,366...80,133,329
|
|
| G
|
Kank1
|
KN motif and ankyrin repeat domains 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KANK1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:232,381,720...232,500,834
Ensembl chr 1:232,445,658...232,500,839
|
|
| G
|
Kank2
|
KN motif and ankyrin repeat domains 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KANK2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:28,587,770...28,617,212
Ensembl chr 8:28,587,770...28,616,993
|
|
| G
|
Kank4
|
KN motif and ankyrin repeat domains 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KANK4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:118,516,994...118,581,024
Ensembl chr 5:118,517,971...118,581,002
|
|
| G
|
Kat6b
|
lysine acetyltransferase 6B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KAT6B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr15:2,688,535...2,861,443
Ensembl chr15:2,688,811...2,844,343
|
|
| G
|
Kbtbd12
|
kelch repeat and BTB domain containing 12
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KBTBD12 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:122,571,903...122,645,895
Ensembl chr 4:122,573,526...122,645,810
|
|
| G
|
Kbtbd3
|
kelch repeat and BTB domain containing 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KBTBD3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:9,749,229...9,780,036
Ensembl chr 8:9,749,175...9,774,555
|
|
| G
|
Kbtbd8
|
kelch repeat and BTB domain containing 8
|
increases expression
|
ISO
|
Nickel results in increased expression of KBTBD8 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:129,232,781...129,245,608
Ensembl chr 4:129,232,027...129,245,605
|
|
| G
|
Kcna1
|
potassium voltage-gated channel subfamily A member 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KCNA1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:161,150,378...161,160,051
Ensembl chr 4:161,147,418...161,160,044
|
|
| G
|
Kcna2
|
potassium voltage-gated channel subfamily A member 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KCNA2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:197,392,746...197,406,606
Ensembl chr 2:197,392,698...197,407,519
|
|
| G
|
Kcna3
|
potassium voltage-gated channel subfamily A member 3
|
increases expression
|
ISO
|
Nickel results in increased expression of KCNA3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:197,320,324...197,322,277
Ensembl chr 2:197,318,134...197,350,739
|
|
| G
|
Kcnab1
|
potassium voltage-gated channel subfamily A regulatory beta subunit 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KCNAB1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:151,446,975...151,913,636
Ensembl chr 2:151,446,947...151,913,636
|
|
| G
|
Kcnab2
|
potassium voltage-gated channel subfamily A regulatory beta subunit 2
|
increases expression
|
ISO
|
Nickel results in increased expression of KCNAB2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:168,182,228...168,270,760
Ensembl chr 5:168,184,613...168,270,760
|
|
| G
|
Kcnb1
|
potassium voltage-gated channel subfamily B member 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KCNB1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:176,239,285...176,332,408
Ensembl chr 3:176,242,589...176,332,408
|
|
| G
|
Kcne4
|
potassium voltage-gated channel subfamily E regulatory subunit 4
|
increases expression
|
ISO
|
Nickel results in increased expression of KCNE4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 9:87,674,264...87,699,088
Ensembl chr 9:87,650,462...87,704,131
|
|
| G
|
Kcnh8
|
potassium voltage-gated channel subfamily H member 8
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KCNH8 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 9:5,742,683...6,182,445
Ensembl chr 9:5,742,683...6,182,445
|
|
| G
|
Kcnip2
|
potassium voltage-gated channel interacting protein 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KCNIP2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:254,590,172...254,614,437
Ensembl chr 1:254,590,175...254,613,898
|
|
| G
|
Kcnj12
|
potassium inwardly-rectifying channel, subfamily J, member 12
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KCNJ12 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:46,196,110...46,245,008
Ensembl chr10:46,195,428...46,260,169
|
|
| G
|
Kcnj15
|
potassium inwardly-rectifying channel, subfamily J, member 15
|
increases expression
|
ISO
|
Nickel results in increased expression of KCNJ15 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr11:48,046,953...48,091,285
Ensembl chr11:48,035,655...48,092,457
|
|
| G
|
Kcnj2
|
potassium inwardly-rectifying channel, subfamily J, member 2
|
increases expression
|
ISO
|
Nickel results in increased expression of KCNJ2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr10:96,560,225...96,570,788
Ensembl chr10:96,565,600...96,570,901
|
|
| G
|
Kcnj8
|
potassium inwardly-rectifying channel, subfamily J, member 8
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KCNJ8 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:177,240,692...177,246,548
Ensembl chr 4:177,239,908...177,246,531
|
|
| G
|
Kcnk5
|
potassium two pore domain channel subfamily K member 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KCNK5 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr15:4,171,625...4,213,896
Ensembl chr15:4,171,610...4,213,897
|
|
| G
|
Kcnk6
|
potassium two pore domain channel subfamily K member 6
|
increases expression
|
ISO
|
Nickel results in increased expression of KCNK6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:93,652,888...93,661,419
|
|
| G
|
Kcnma1
|
potassium calcium-activated channel subfamily M alpha 1
|
multiple interactions decreases expression affects expression
|
ISO
|
trichostatin A inhibits the reaction [Nickel affects the expression of KCNMA1 mRNA] Nickel results in decreased expression of KCNMA1 mRNA
|
CTD |
PMID:14575637 PMID:24768652 PMID:25583101 |
|
NCBI chr15:351,065...1,057,117
Ensembl chr15:351,659...1,057,117
|
|
| G
|
Kcnmb4
|
potassium calcium-activated channel subfamily M regulatory beta subunit 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KCNMB4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:53,952,150...54,005,101
Ensembl chr 7:53,949,881...54,005,281
|
|
| G
|
Kctd4
|
potassium channel tetramerization domain containing 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KCTD4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr15:57,675,024...57,686,816
Ensembl chr15:57,673,741...57,687,798
|
|
| G
|
Kctd5
|
potassium channel tetramerization domain containing 5
|
increases expression
|
ISO
|
Nickel results in increased expression of KCTD5 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:13,583,781...13,609,762
Ensembl chr10:13,583,781...13,610,062
|
|
| G
|
Kdelr2
|
KDEL endoplasmic reticulum protein retention receptor 2
|
increases expression
|
ISO
|
Nickel results in increased expression of KDELR2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr12:16,252,424...16,270,737
Ensembl chr12:16,252,424...16,270,719
|
|
| G
|
Kdm1b
|
lysine demethylase 1B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KDM1B mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr17:17,809,232...17,850,141
Ensembl chr17:17,809,232...17,850,068
|
|
| G
|
Kdm3a
|
lysine demethylase 3A
|
multiple interactions increases expression
|
ISO
|
HIF1A mRNA affects the reaction [Nickel results in increased expression of KDM3A mRNA]; HIF1A mRNA affects the reaction [Nickel results in increased expression of KDM3A protein]; KDM3A mRNA affects the reaction [Nickel results in increased phosphorylation of MAPK1 protein]; KDM3A mRNA affects the reaction [Nickel results in increased phosphorylation of MAPK3 protein]; KDM3A protein inhibits the reaction [Nickel results in increased phosphorylation of MAPK1 protein]; KDM3A protein inhibits the reaction [Nickel results in increased phosphorylation of MAPK3 protein] Nickel results in increased expression of KDM3A mRNA; Nickel results in increased expression of KDM3A protein
|
CTD |
PMID:20881000 |
|
NCBI chr 4:105,189,208...105,233,526
Ensembl chr 4:105,189,208...105,233,370
|
|
| G
|
Kdm7a
|
lysine demethylase 7A
|
increases expression
|
ISO
|
Nickel results in increased expression of KDM7A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:68,866,263...68,992,979
Ensembl chr 4:68,871,677...68,931,506
|
|
| G
|
Kdr
|
kinase insert domain receptor
|
decreases expression
|
ISO
|
Nickel analog results in decreased expression of KDR mRNA
|
CTD |
PMID:25144474 |
|
NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,572,049...32,615,192
|
|
| G
|
Keap1
|
Kelch-like ECH-associated protein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of KEAP1 protein
|
CTD |
PMID:19033392 |
|
NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:28,044,555...28,054,042
|
|
| G
|
Kiaa0040
|
KIAA0040 ortholog
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KIAA0040 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr13:74,807,959...74,845,530
Ensembl chr13:74,807,982...74,845,530
|
|
| G
|
Kiaa0930
|
KIAA0930 homolog
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KIAA0930 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 7:117,947,898...117,987,601
Ensembl chr 7:117,947,898...117,987,636
|
|
| G
|
Kiaa1549
|
KIAA1549 homolog
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KIAA1549 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:67,807,635...67,935,303
Ensembl chr 4:67,811,803...67,935,360
|
|
| G
|
Kif14
|
kinesin family member 14
|
increases expression
|
ISO
|
Nickel results in increased expression of KIF14 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:50,478,646...50,542,256
Ensembl chr13:50,478,721...50,542,248
|
|
| G
|
Kif18b
|
kinesin family member 18B
|
increases expression
|
ISO
|
Nickel results in increased expression of KIF18B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:88,370,520...88,392,388
Ensembl chr10:88,370,524...88,389,691
|
|
| G
|
Kif1b
|
kinesin family member 1B
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of KIF1B mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr 5:164,890,778...165,025,848
Ensembl chr 5:164,894,763...165,008,841
|
|
| G
|
Kif21b
|
kinesin family member 21B
|
increases expression
|
ISO
|
Nickel results in increased expression of KIF21B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:50,127,842...50,177,822
Ensembl chr13:50,127,842...50,177,822
|
|
| G
|
Kif26b
|
kinesin family member 26B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KIF26B mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr13:92,815,427...93,221,071
Ensembl chr13:92,815,427...93,215,453
|
|
| G
|
Kif2a
|
kinesin family member 2A
|
increases expression
|
ISO
|
Nickel results in increased expression of KIF2A mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:40,101,548...40,164,780
Ensembl chr 2:40,101,548...40,186,618
|
|
| G
|
Kif2c
|
kinesin family member 2C
|
increases expression
|
ISO
|
Nickel results in increased expression of KIF2C mRNA
|
CTD |
PMID:19031421 |
|
NCBI chr 5:135,873,925...135,899,267
Ensembl chr 5:135,873,925...135,899,212
|
|
| G
|
Kif5b
|
kinesin family member 5B
|
increases expression
|
ISO
|
Nickel results in increased expression of KIF5B mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr17:56,185,386...56,222,990
Ensembl chr17:56,185,380...56,223,008
|
|
| G
|
Kif5c
|
kinesin family member 5C
|
increases expression
|
ISO
|
Nickel results in increased expression of KIF5C mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:54,441,266...54,591,630
Ensembl chr 3:54,441,310...54,594,813
|
|
| G
|
Kit
|
KIT proto-oncogene receptor tyrosine kinase
|
multiple interactions increases expression
|
EXP
|
Grape Seed Proanthocyanidins inhibits the reaction [Nickel results in increased expression of KIT protein]
|
CTD |
PMID:21417627 |
|
NCBI chr14:32,901,615...32,978,895
Ensembl chr14:32,903,033...32,978,812
|
|
| G
|
Kiz
|
kizuna centrosomal protein
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KIZ mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:154,730,873...154,838,410
Ensembl chr 3:154,730,634...154,838,410
|
|
| G
|
Klb
|
klotho beta
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KLB mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:43,253,963...43,304,532
Ensembl chr14:43,253,255...43,304,515
|
|
| G
|
Klc4
|
kinesin light chain 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KLC4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 9:21,834,765...21,848,676
Ensembl chr 9:21,835,092...21,848,675
|
|
| G
|
Klf15
|
KLF transcription factor 15
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KLF15 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:124,522,652...124,535,613
Ensembl chr 4:124,522,909...124,542,373
|
|
| G
|
Klf6
|
KLF transcription factor 6
|
increases expression
|
ISO
|
Nickel results in increased expression of KLF6 mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr17:69,449,483...69,458,478
Ensembl chr17:69,441,493...69,498,601
|
|
| G
|
Klf8
|
KLF transcription factor 8
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KLF8 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr X:21,329,081...21,508,720
|
|
| G
|
Klhdc1
|
kelch domain containing 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KLHDC1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:93,406,226...93,501,475
Ensembl chr 6:93,448,758...93,501,702
|
|
| G
|
Klhdc7b
|
kelch domain containing 7B
|
increases expression
|
ISO
|
Nickel results in increased expression of KLHDC7B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:122,331,708...122,335,364
Ensembl chr 7:122,331,708...122,335,364
|
|
| G
|
Klhdc8b
|
kelch domain containing 8B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KLHDC8B mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:118,020,136...118,025,102
Ensembl chr 8:118,020,376...118,025,102
|
|
| G
|
Klhl13
|
kelch-like family member 13
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KLHL13 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr X:118,747,298...118,912,279
Ensembl chr X:118,747,298...118,855,035
|
|
| G
|
Klhl2
|
kelch-like family member 2
|
increases expression
|
ISO
|
Nickel results in increased expression of KLHL2 mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr16:29,627,171...29,739,782
Ensembl chr16:29,627,237...29,739,957
|
|
| G
|
Klhl31
|
kelch-like family member 31
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KLHL31 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:87,395,878...87,419,236
Ensembl chr 8:87,395,869...87,419,258
|
|
| G
|
Klhl6
|
kelch-like family member 6
|
increases expression
|
ISO
|
Nickel results in increased expression of KLHL6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:94,475,262...94,514,653
Ensembl chr11:94,475,262...94,514,623
|
|
| G
|
Klhl8
|
kelch-like family member 8
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KLHL8 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr14:6,112,472...6,158,001
Ensembl chr14:6,112,490...6,157,966
|
|
| G
|
Klk10
|
kallikrein related-peptidase 10
|
increases expression
|
ISO
|
Nickel results in increased expression of KLK10 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:103,371,638...103,375,918
Ensembl chr 1:103,371,638...103,375,918
|
|
| G
|
Klk13
|
kallikrein related-peptidase 13
|
increases expression
|
ISO
|
Nickel results in increased expression of KLK13 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:103,301,935...103,314,313
Ensembl chr 1:103,301,935...103,313,554
|
|
| G
|
Klk1b3
|
kallikrein 1-related peptidase B3
|
decreases expression
|
EXP
|
Nickel results in decreased expression of KLK1B3 mRNA
|
CTD |
PMID:19130878 |
|
NCBI chr 1:103,845,647...103,849,854
Ensembl chr 1:103,845,603...103,849,855
|
|
| G
|
Klk6
|
kallikrein related-peptidase 6
|
increases expression
|
ISO
|
Nickel results in increased expression of KLK6 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:103,415,411...103,422,682
Ensembl chr 1:103,416,886...103,422,690
|
|
| G
|
Klrb1
|
killer cell lectin like receptor B1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KLRF1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 4:164,142,323...164,161,018
Ensembl chr 4:164,142,280...164,161,764
|
|
| G
|
Klrb1a
|
killer cell lectin like receptor B1A
|
increases expression
|
ISO
|
Nickel results in increased expression of KLRB1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:163,576,672...163,590,201
Ensembl chr 4:163,576,672...163,619,374
|
|
| G
|
Klrd1
|
killer cell lectin like receptor D1
|
increases expression
|
ISO
|
Nickel results in increased expression of KLRD1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 4:164,730,833...164,742,539
Ensembl chr 4:164,730,856...164,742,538
|
|
| G
|
Klrg1
|
killer cell lectin like receptor G1
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of KLRG1 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of KLRG1 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 4:157,127,571...157,139,372
Ensembl chr 4:157,127,571...157,139,372
|
|
| G
|
Klrg2
|
killer cell lectin like receptor G2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KLRG2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:68,314,347...68,341,759
Ensembl chr 4:68,330,660...68,341,043
|
|
| G
|
Klrk1
|
killer cell lectin like receptor K1
|
increases expression
|
ISO
|
Nickel results in increased expression of KLRK1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:164,767,377...164,778,453
Ensembl chr 4:164,767,946...164,778,382
|
|
| G
|
Kmo
|
kynurenine 3-monooxygenase
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of KMO mRNA Nickel results in increased expression of KMO mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr13:90,089,340...90,121,108
Ensembl chr13:90,089,463...90,125,151
|
|
| G
|
Kng1
|
kininogen 1
|
affects binding
|
ISO
|
KNG1 protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr11:91,317,354...91,340,148
Ensembl chr11:91,317,355...91,340,148
|
|
| G
|
Kpna2
|
karyopherin subunit alpha 2
|
increases expression
|
ISO
|
Nickel results in increased expression of KPNA2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:92,433,678...92,445,841
Ensembl chr10:92,433,679...92,445,937
|
|
| G
|
Kpna4
|
karyopherin subunit alpha 4
|
increases expression
|
ISO
|
Nickel results in increased expression of KPNA4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:155,635,679...155,691,056
Ensembl chr 2:155,634,247...155,691,053
|
|
| G
|
Krcc1
|
lysine-rich coiled-coil 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KRCC1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 4:104,819,958...104,832,987
Ensembl chr 4:104,819,190...104,855,484
|
|
| G
|
Krt1
|
keratin 1
|
affects binding
|
ISO
|
KRT1 protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr 7:134,855,311...134,860,537
Ensembl chr 7:134,855,313...134,860,537
|
|
| G
|
Krt10
|
keratin 10
|
affects expression affects binding multiple interactions
|
ISO
|
Nickel affects the expression of KRT10 mRNA KRT10 protein binds to Nickel trichostatin A inhibits the reaction [Nickel affects the expression of KRT10 mRNA]
|
CTD |
PMID:14575637 PMID:23896426 |
|
NCBI chr10:84,834,865...84,839,160
Ensembl chr10:84,834,840...84,839,160
|
|
| G
|
Krt14
|
keratin 14
|
affects binding
|
ISO
|
KRT14 protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr10:85,638,182...85,642,450
|
|
| G
|
Krt15
|
keratin 15
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KRT15 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:85,567,197...85,571,014
Ensembl chr10:85,567,202...85,571,142
|
|
| G
|
Krt16
|
keratin 16
|
affects binding increases expression
|
ISO
|
KRT16 protein binds to Nickel Nickel results in increased expression of KRT16 mRNA
|
CTD |
PMID:23896426 PMID:25583101 |
|
NCBI chr10:85,669,276...85,672,211
Ensembl chr10:85,669,276...85,672,211
|
|
| G
|
Krt18
|
keratin 18
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KRT18 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:135,036,168...135,039,844
Ensembl chr 7:135,035,982...135,039,848 Ensembl chr10:135,035,982...135,039,848
|
|
| G
|
Krt19
|
keratin 19
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KRT19 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:85,576,235...85,580,952
Ensembl chr10:85,576,235...85,580,952
|
|
| G
|
Krt2
|
keratin 2
|
affects binding
|
ISO
|
KRT2 protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr 7:134,819,584...134,826,736
Ensembl chr 7:134,819,584...134,827,011
|
|
| G
|
Krt222
|
keratin 222
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KRT222 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:84,680,331...84,693,374
Ensembl chr10:84,680,331...84,692,173
|
|
| G
|
Krt4
|
keratin 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KRT4 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 7:134,924,753...134,931,050
Ensembl chr 7:134,924,753...134,930,713
|
|
| G
|
Krt5
|
keratin 5
|
affects binding
|
ISO
|
KRT5 protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr 7:134,724,840...134,730,569
Ensembl chr 7:134,724,840...134,730,569
|
|
| G
|
Krt6c
|
keratin 6c
|
affects binding
|
ISO
|
KRT6C protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr 7:134,678,316...134,682,753
Ensembl chr 7:134,678,324...134,682,753
|
|
| G
|
Krt7
|
keratin 7
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KRT7 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:134,407,626...134,423,787
Ensembl chr 7:134,407,584...134,423,786
|
|
| G
|
Krt77
|
keratin 77
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KRT77 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:134,868,416...134,880,776
Ensembl chr 7:134,868,416...134,880,776
|
|
| G
|
Krt9
|
keratin 9
|
affects binding
|
ISO
|
KRT9 protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr10:85,621,360...85,627,626
Ensembl chr10:85,621,360...85,627,626
|
|
| G
|
Ky
|
kyphoscoliosis peptidase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of KY mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 8:111,965,862...112,005,206
Ensembl chr 8:111,965,862...112,005,206
|
|
| G
|
Kynu
|
kynureninase
|
increases expression
|
ISO
|
Nickel results in increased expression of KYNU mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:48,188,286...48,338,996
Ensembl chr 3:48,188,182...48,339,014
|
|
| G
|
L3hypdh
|
trans-L-3-hydroxyproline dehydratase
|
increases expression
|
ISO
|
Nickel results in increased expression of L3HYPDH mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 6:96,372,243...96,383,039
|
|
| G
|
L3mbtl1
|
L3MBTL histone methyl-lysine binding protein 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of L3MBTL1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:172,014,774...172,053,181
Ensembl chr 3:172,021,416...172,053,181
|
|
| G
|
Lactb
|
lactamase, beta
|
increases expression
|
ISO
|
Nickel results in increased expression of LACTB mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:76,452,679...76,469,986
Ensembl chr 8:76,452,349...76,468,716
|
|
| G
|
Lactb2
|
lactamase, beta 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LACTB2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 5:10,352,165...10,374,928
Ensembl chr 5:10,352,154...10,379,255
|
|
| G
|
Lad1
|
ladinin 1
|
increases expression
|
ISO
|
Nickel results in increased expression of LAD1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:49,801,347...49,815,709
Ensembl chr13:49,800,472...49,815,709
|
|
| G
|
Lag3
|
lymphocyte activating 3
|
increases expression
|
ISO
|
Nickel results in increased expression of LAG3 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 4:159,398,930...159,407,001
Ensembl chr 4:159,398,932...159,406,669
|
|
| G
|
Lair1
|
leukocyte-associated immunoglobulin-like receptor 1
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of LAIR1 mRNA Nickel results in increased expression of LAIR1 mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr 1:79,140,850...79,261,546
Ensembl chr 1:79,198,311...79,258,037
|
|
| G
|
Lama2
|
laminin subunit alpha 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LAMA2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:19,492,126...20,140,056
Ensembl chr 1:19,244,599...20,140,056
|
|
| G
|
Lamb2
|
laminin subunit beta 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LAMB2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:118,056,899...118,069,090
Ensembl chr 8:118,056,935...118,069,090
|
|
| G
|
Lamp3
|
lysosomal-associated membrane protein 3
|
increases expression
|
ISO
|
Nickel results in increased expression of LAMP3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:94,657,817...94,726,451
Ensembl chr11:94,661,399...94,726,195
|
|
| G
|
Lap3
|
leucine aminopeptidase 3
|
increases expression increases activity
|
ISO EXP
|
Nickel results in increased expression of LAP3 mRNA Nickel results in increased activity of LAP3 protein
|
CTD |
PMID:16819762 PMID:24768652 PMID:25583101 |
|
NCBI chr14:69,820,907...69,839,891
Ensembl chr14:69,820,908...69,839,891
|
|
| G
|
Laptm5
|
lysosomal protein transmembrane 5
|
increases expression
|
ISO
|
Nickel results in increased expression of LAPTM5 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:148,371,880...148,393,927
Ensembl chr 5:148,339,435...148,393,927
|
|
| G
|
Large2
|
LARGE xylosyl- and glucuronyltransferase 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LARGE2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:98,791,543...98,800,251
Ensembl chr 3:98,791,543...98,797,782
|
|
| G
|
Larp1b
|
La ribonucleoprotein 1B
|
increases expression
|
ISO
|
Nickel results in increased expression of LARP1B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:125,860,935...125,897,189
Ensembl chr 2:125,863,997...125,897,189
|
|
| G
|
Larp4b
|
La ribonucleoprotein 4B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LARP4B mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr17:65,813,125...65,908,920
Ensembl chr17:65,830,022...65,908,676
|
|
| G
|
Larp6
|
La ribonucleoprotein 6, translational regulator
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LARP6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:70,079,753...70,101,175
Ensembl chr 8:70,079,647...70,101,198
|
|
| G
|
Lat
|
linker for activation of T cells
|
increases expression
|
ISO
|
Nickel results in increased expression of LAT mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 1:190,367,111...190,372,515
Ensembl chr 1:190,367,109...190,372,153
|
|
| G
|
Lat2
|
linker for activation of T cells family, member 2
|
increases expression
|
ISO
|
Nickel results in increased expression of LAT2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr12:27,740,647...27,754,760
Ensembl chr12:27,740,654...27,755,843
|
|
| G
|
Lax1
|
lymphocyte transmembrane adaptor 1
|
increases expression
|
ISO
|
Nickel results in increased expression of LAX1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:47,686,840...47,697,396
Ensembl chr13:47,686,849...47,697,460
|
|
| G
|
Lbp
|
lipopolysaccharide binding protein
|
affects binding increases expression
|
ISO
|
LBP protein binds to Nickel Nickel results in increased expression of LBP mRNA
|
CTD |
PMID:23896426 PMID:24768652 PMID:25583101 |
|
NCBI chr 3:167,373,786...167,400,941
Ensembl chr 3:167,373,924...167,401,518
|
|
| G
|
Lbr
|
lamin B receptor
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LBR mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr13:96,071,058...96,095,709
Ensembl chr13:96,071,081...96,095,709
|
|
| G
|
Lca5
|
lebercilin LCA5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LCA5 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 8:93,187,735...93,255,060
Ensembl chr 8:93,197,702...93,254,991
|
|
| G
|
Lce1e
|
late cornified envelope 1E
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LCE1E mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:181,157,709...181,159,042
Ensembl chr 2:181,157,709...181,159,042
|
|
| G
|
Lck
|
LCK proto-oncogene, Src family tyrosine kinase
|
increases expression
|
ISO
|
Nickel results in increased expression of LCK mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:147,172,642...147,201,267
Ensembl chr 5:147,172,642...147,201,267
|
|
| G
|
Lcn2
|
lipocalin 2
|
increases expression
|
ISO
|
Nickel results in increased expression of LCN2 mRNA
|
CTD |
PMID:12540486 PMID:24768652 PMID:25583101 |
|
NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:36,078,436...36,081,842
|
|
| G
|
Lcp1
|
lymphocyte cytosolic protein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of LCP1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr15:56,846,375...56,954,090
Ensembl chr15:56,847,433...56,954,092
|
|
| G
|
Lcp2
|
lymphocyte cytosolic protein 2
|
increases expression
|
ISO
|
Nickel results in increased expression of LCP2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:19,146,846...19,193,750
Ensembl chr10:19,146,554...19,193,744
|
|
| G
|
Lct
|
lactase
|
increases activity
|
EXP
|
Nickel results in increased activity of LCT protein
|
CTD |
PMID:16819762 |
|
NCBI chr13:42,334,347...42,376,872
Ensembl chr13:42,334,347...42,376,872
|
|
| G
|
Ldb2
|
LIM domain binding 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LDB2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr14:70,489,243...70,810,573
Ensembl chr14:70,489,620...70,810,574
|
|
| G
|
Ldb3
|
LIM domain binding 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LDB3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr16:9,862,161...9,926,338
Ensembl chr16:9,862,161...9,926,985
|
|
| G
|
Ldha
|
lactate dehydrogenase A
|
multiple interactions increases expression
|
ISO
|
Celecoxib inhibits the reaction [Nickel results in increased expression of LDHA mRNA]; Dexamethasone inhibits the reaction [Nickel results in increased expression of LDHA mRNA]; Indomethacin inhibits the reaction [Nickel results in increased expression of LDHA mRNA]
|
CTD |
PMID:27452194 |
|
NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521
|
|
| G
|
Ldhd
|
lactate dehydrogenase D
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LDHD mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr19:56,492,827...56,497,695
Ensembl chr19:56,482,924...56,509,197
|
|
| G
|
Ldlr
|
low density lipoprotein receptor
|
increases expression
|
ISO
|
Nickel results in increased expression of LDLR mRNA
|
CTD |
PMID:23195993 PMID:24768652 |
|
NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:28,546,146...28,570,675
|
|
| G
|
Lef1
|
lymphoid enhancer binding factor 1
|
increases expression
|
ISO
|
Nickel results in increased expression of LEF1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:222,340,541...222,453,931
Ensembl chr 2:222,340,704...222,453,929
|
|
| G
|
Leo1
|
LEO1 homolog, Paf1/RNA polymerase II complex component
|
increases expression
|
ISO
|
Nickel results in increased expression of LEO1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:85,080,036...85,104,471
Ensembl chr 8:85,079,996...85,105,094
|
|
| G
|
Lep
|
leptin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LEP mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:58,626,523...58,640,661
|
|
| G
|
Lepr
|
leptin receptor
|
decreases expression multiple interactions
|
ISO EXP
|
Nickel results in decreased expression of LEPR mRNA [nickel sulfate results in increased abundance of Nickel] which results in increased expression of LEPR mRNA
|
CTD |
PMID:24768652 PMID:31734292 |
|
NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215
|
|
| G
|
Lfng
|
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LFNG mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr12:19,144,474...19,152,951
Ensembl chr12:19,124,662...19,152,918
|
|
| G
|
Lgals2
|
galectin 2
|
increases expression
|
ISO
|
Nickel results in increased expression of LGALS2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:112,283,630...112,290,228
Ensembl chr 7:112,282,822...112,285,392
|
|
| G
|
Lgals3
|
galectin 3
|
increases expression
|
ISO
|
Nickel results in increased expression of LGALS3 mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr15:23,099,795...23,111,731
Ensembl chr15:23,086,841...23,111,737
|
|
| G
|
Lgals9
|
galectin 9
|
increases expression
|
ISO
|
Nickel results in increased expression of LGALS9 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:64,405,044...64,428,249
Ensembl chr10:64,405,044...64,428,070
|
|
| G
|
Lgi4
|
leucine-rich repeat LGI family, member 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LGI4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:95,422,461...95,433,296
Ensembl chr 1:95,414,058...95,433,289
|
|
| G
|
Lgr4
|
leucine-rich repeat-containing G protein-coupled receptor 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LGR4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:116,901,968...117,004,584
Ensembl chr 3:116,901,968...117,004,153
|
|
| G
|
Lgr5
|
leucine rich repeat containing G protein coupled receptor 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LGR5 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:52,973,151...53,107,964
Ensembl chr 7:52,974,332...53,108,163
|
|
| G
|
Lgr6
|
leucine-rich repeat-containing G protein-coupled receptor 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LGR6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:48,976,193...49,095,870
Ensembl chr13:48,976,193...49,095,857
|
|
| G
|
Lhb
|
luteinizing hormone subunit beta
|
increases expression
|
EXP
|
Nickel analog results in increased expression of LHB protein
|
CTD |
PMID:25407529 |
|
NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445
|
|
| G
|
Lilrb3
|
leukocyte immunoglobulin like receptor B3
|
increases expression
|
ISO
|
Nickel results in increased expression of LILRB5 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:79,001,483...79,011,054
Ensembl chr 1:79,001,600...79,010,981
|
|
| G
|
Lilrb4
|
leukocyte immunoglobulin like receptor B4
|
increases expression
|
ISO
|
Nickel results in increased expression of LILRB4 mRNA Nickel results in increased expression of LILRB4B mRNA
|
CTD |
PMID:12540486 PMID:24768652 PMID:25583101 |
|
NCBI chr 1:78,847,685...78,853,294
Ensembl chr 1:78,847,685...78,853,326
|
|
| G
|
Limd2
|
LIM domain containing 2
|
increases expression
|
ISO
|
Nickel results in increased expression of LIMD2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:91,590,079...91,592,747
Ensembl chr10:91,590,082...91,592,439
|
|
| G
|
Lin7b
|
lin-7 homolog B, crumbs cell polarity complex component
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LIN7B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:104,983,368...104,986,795
Ensembl chr 1:104,982,771...104,986,078
|
|
| G
|
Lins1
|
lines homolog 1
|
increases expression
|
ISO
|
Nickel results in increased expression of LINS1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:129,677,815...129,705,399
Ensembl chr 1:129,692,225...129,703,826
|
|
| G
|
Lipa
|
lipase A, lysosomal acid type
|
affects expression increases expression multiple interactions
|
ISO
|
Nickel affects the expression of LIPA mRNA Nickel results in increased expression of LIPA mRNA trichostatin A inhibits the reaction [Nickel affects the expression of LIPA mRNA]
|
CTD |
PMID:14575637 PMID:24768652 PMID:25583101 |
|
NCBI chr 1:241,437,524...241,470,936
Ensembl chr 1:241,437,524...241,470,740
|
|
| G
|
Lipe
|
lipase E, hormone sensitive type
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LIPE mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:90,093,433...90,112,117
Ensembl chr 1:90,093,433...90,112,117
|
|
| G
|
Lipg
|
lipase G, endothelial type
|
increases expression
|
ISO
|
Nickel results in increased expression of LIPG mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr18:70,790,077...70,811,259
Ensembl chr18:70,790,077...70,812,260
|
|
| G
|
Liph
|
lipase H
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LIPH mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:92,536,724...92,586,117
Ensembl chr11:92,537,860...92,586,120
|
|
| G
|
Litaf
|
lipopolysaccharide-induced TNF factor
|
increases expression
|
ISO
|
Nickel results in increased expression of LITAF mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr10:5,163,258...5,199,930
Ensembl chr10:5,163,242...5,199,930
|
|
| G
|
Llgl2
|
LLGL scribble cell polarity complex component 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LLGL2 mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr10:101,549,911...101,585,466
Ensembl chr10:101,549,862...101,585,464
|
|
| G
|
Llph
|
LLP homolog, long-term synaptic facilitation factor
|
increases expression
|
ISO
|
Nickel results in increased expression of LLPH mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:57,620,925...57,625,924
Ensembl chr 7:57,620,993...57,625,925
|
|
| G
|
Lmf1
|
lipase maturation factor 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LMF1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:15,094,432...15,188,665
Ensembl chr10:15,098,138...15,188,664
|
|
| G
|
Lmna
|
lamin A/C
|
increases expression
|
ISO
|
Nickel results in increased expression of LMNA mRNA
|
CTD |
PMID:23195993 PMID:24768652 |
|
NCBI chr 2:176,237,564...176,265,301
Ensembl chr 2:176,237,564...176,288,072
|
|
| G
|
Lmnb1
|
lamin B1
|
increases expression
|
ISO
|
Nickel results in increased expression of LMNB1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr18:52,373,939...52,413,284
Ensembl chr18:52,373,757...52,413,283
|
|
| G
|
Lmnb2
|
lamin B2
|
increases expression
|
ISO
|
Nickel results in increased expression of LMNB2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:9,443,308...9,459,468
Ensembl chr 7:9,440,128...9,459,342
|
|
| G
|
Lmo3
|
LIM domain only 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LMO3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:172,965,944...173,028,980
Ensembl chr 4:172,965,951...173,025,156
|
|
| G
|
Lmo4
|
LIM domain only 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LMO4 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 2:235,924,574...235,941,609
Ensembl chr 2:235,924,403...235,941,275
|
|
| G
|
Lmod1
|
leiomodin 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LMOD1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:49,305,693...49,347,970
Ensembl chr13:49,305,830...49,348,116
|
|
| G
|
Lnp1
|
leukemia NUP98 fusion partner 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LNP1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr11:57,129,986...57,149,594
Ensembl chr11:57,123,129...57,148,586
|
|
| G
|
LOC102546572
|
zinc finger protein 709-like
|
increases expression
|
ISO
|
Nickel results in increased expression of ZNF136 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 7:12,496,595...12,519,259
Ensembl chr 7:12,504,501...12,519,295
|
|
| G
|
Lonrf1
|
LON peptidase N-terminal domain and ring finger 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LONRF1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr16:62,687,931...62,718,525
Ensembl chr16:62,687,746...62,718,520
|
|
| G
|
Lonrf2
|
LON peptidase N-terminal domain and ring finger 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LONRF2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:48,524,962...48,566,353
Ensembl chr 9:48,530,549...48,570,807
|
|
| G
|
Lox
|
lysyl oxidase
|
increases expression
|
ISO
|
Nickel results in increased expression of LOX mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr18:48,162,889...48,175,640
Ensembl chr18:48,165,688...48,239,810
|
|
| G
|
Lpar4
|
lysophosphatidic acid receptor 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LPAR4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr X:76,106,319...76,119,807
Ensembl chr X:76,106,071...76,119,808
|
|
| G
|
Lpar6
|
lysophosphatidic acid receptor 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LPAR6 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr15:54,826,110...54,827,919
Ensembl chr15:54,823,717...54,978,783
|
|
| G
|
Lpgat1
|
lysophosphatidylglycerol acyltransferase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of LPGAT1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr13:105,825,630...105,896,366
Ensembl chr13:105,820,468...105,896,364
|
|
| G
|
Lpl
|
lipoprotein lipase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LPL mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr16:25,596,205...25,621,928
Ensembl chr16:25,596,211...25,622,107
|
|
| G
|
Lpxn
|
leupaxin
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of LPXN mRNA Nickel results in increased expression of LPXN mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 1:219,353,319...219,387,743
Ensembl chr 1:219,353,708...219,387,742
|
|
| G
|
Lrg1
|
leucine-rich alpha-2-glycoprotein 1
|
increases expression affects binding
|
ISO
|
Nickel results in increased expression of LRG1 mRNA LRG1 protein binds to Nickel
|
CTD |
PMID:12540486 PMID:23896426 |
|
NCBI chr 9:1,034,691...1,036,937
Ensembl chr 9:1,034,679...1,037,337
|
|
| G
|
Lrif1
|
ligand dependent nuclear receptor interacting factor 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LRIF1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 2:196,919,606...197,010,713
Ensembl chr 2:196,919,151...197,010,717
|
|
| G
|
Lrp4
|
LDL receptor related protein 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LRP4 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 3:97,885,373...97,939,366
Ensembl chr 3:97,885,400...97,939,370
|
|
| G
|
Lrp5
|
LDL receptor related protein 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LRP5 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:210,243,499...210,346,886
Ensembl chr 1:210,243,502...210,346,822
|
|
| G
|
Lrp8
|
LDL receptor related protein 8
|
increases expression
|
ISO
|
Nickel results in increased expression of LRP8 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:127,792,236...127,864,207
Ensembl chr 5:127,792,299...127,864,207
|
|
| G
|
Lrr1
|
leucine rich repeat protein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of LRR1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 6:93,379,159...93,387,950
Ensembl chr 6:93,379,169...93,387,950
|
|
| G
|
Lrrc1
|
leucine rich repeat containing 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LRRC1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:87,120,281...87,289,748
Ensembl chr 8:87,119,975...87,286,853
|
|
| G
|
Lrrc17
|
leucine rich repeat containing 17
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LRRC17 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:14,393,632...14,424,048
Ensembl chr 4:14,393,640...14,424,048
|
|
| G
|
Lrrc25
|
leucine rich repeat containing 25
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LRRC25 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr16:18,840,867...18,847,722
Ensembl chr16:18,840,867...18,846,464
|
|
| G
|
Lrrc32
|
leucine rich repeat containing 32
|
increases expression
|
ISO
|
Nickel results in increased expression of LRRC32 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:162,196,995...162,209,563
Ensembl chr 1:162,197,653...162,209,563
|
|
| G
|
Lrrc34
|
leucine rich repeat containing 34
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LRRC34 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 2:114,680,787...114,702,961
Ensembl chr 2:114,680,094...114,702,961
|
|
| G
|
Lrrc36
|
leucine rich repeat containing 36
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LRRC36 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr19:50,201,944...50,252,338
Ensembl chr19:50,201,987...50,252,338
|
|
| G
|
Lrrc59
|
leucine rich repeat containing 59
|
increases expression
|
ISO
|
Nickel results in increased expression of LRRC59 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:80,069,162...80,083,820
Ensembl chr10:80,069,120...80,084,079
|
|
| G
|
Lrrc8b
|
leucine rich repeat containing 8 VRAC subunit B
|
increases expression
|
ISO
|
Nickel results in increased expression of LRRC8B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr14:4,655,273...4,721,648
Ensembl chr14:4,655,273...4,721,076
|
|
| G
|
Lrrc8c
|
leucine rich repeat containing 8 VRAC subunit C
|
increases expression
|
ISO
|
Nickel results in increased expression of LRRC8C mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:4,528,721...4,621,259
Ensembl chr14:4,531,823...4,620,049
|
|
| G
|
Lrrk2
|
leucine-rich repeat kinase 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LRRK2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 7:124,706,246...124,867,234
Ensembl chr 7:124,706,080...124,867,239
|
|
| G
|
Lrrn1
|
leucine rich repeat neuronal 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LRRN1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:142,032,805...142,072,320
Ensembl chr 4:142,032,041...142,074,760
|
|
| G
|
Lrrn3
|
leucine rich repeat neuronal 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LRRN3 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 6:64,216,164...64,247,293
Ensembl chr 6:64,215,878...64,247,614
|
|
| G
|
Lsamp
|
limbic system-associated membrane protein
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LSAMP mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:72,053,285...74,223,019
Ensembl chr11:72,053,285...72,702,134
|
|
| G
|
Lsm10
|
LSM10, U7 small nuclear RNA associated
|
increases expression
|
ISO
|
Nickel results in increased expression of LSM10 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:143,649,817...143,660,391
Ensembl chr 5:143,615,360...143,663,986
|
|
| G
|
Lss
|
lanosterol synthase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LSS mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr20:12,090,641...12,118,230
Ensembl chr20:12,073,543...12,118,253
|
|
| G
|
Lst1
|
leukocyte specific transcript 1
|
increases expression
|
ISO
|
Nickel results in increased expression of LST1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr20:3,639,353...3,644,399
Ensembl chr20:3,639,341...3,642,669
|
|
| G
|
Lta
|
lymphotoxin alpha
|
multiple interactions
|
EXP
|
[Nickel co-treated with Cobalt co-treated with Tungsten] results in increased expression of LTA mRNA; [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of LTA mRNA
|
CTD |
PMID:22198552 |
|
NCBI chr20:3,622,291...3,625,852
Ensembl chr20:3,623,527...3,625,533
|
|
| G
|
Lta4h
|
leukotriene A4 hydrolase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LTA4H mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 7:29,856,846...29,888,642
Ensembl chr 7:29,856,802...29,888,641
|
|
| G
|
Ltb
|
lymphotoxin beta
|
increases expression
|
ISO
|
Nickel results in increased expression of LTB mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr20:3,632,209...3,634,054
Ensembl chr20:3,632,210...3,634,054
|
|
| G
|
Ltb4r
|
leukotriene B4 receptor
|
increases expression
|
ISO
|
Nickel results in increased expression of LTB4R mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr15:33,233,120...33,235,636
Ensembl chr15:33,232,820...33,235,637
|
|
| G
|
Ltbp1
|
latent transforming growth factor beta binding protein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of LTBP1 mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr 6:25,781,625...26,177,346
Ensembl chr 6:25,781,638...26,454,036
|
|
| G
|
Ltbp2
|
latent transforming growth factor beta binding protein 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LTBP2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:110,161,029...110,261,586
Ensembl chr 6:110,161,029...110,257,298
|
|
| G
|
Ltbp4
|
latent transforming growth factor beta binding protein 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LTBP4 mRNA
|
CTD |
PMID:12540486 PMID:24768652 PMID:25583101 |
|
NCBI chr 1:91,727,769...91,759,822
Ensembl chr 1:91,727,769...91,760,006
|
|
| G
|
Ltf
|
lactotransferrin
|
increases expression
|
ISO
|
Nickel results in increased expression of LTF mRNA
|
CTD |
PMID:12540486 PMID:25583101 |
|
NCBI chr 8:119,878,344...119,901,189
Ensembl chr 8:119,878,344...119,901,189
|
|
| G
|
Lvrn
|
laeverin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LVRN mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr18:41,752,788...41,861,830
Ensembl chr18:41,794,114...41,861,851
|
|
| G
|
Ly6al1
|
lymphocyte antigen 6 complex, locus A like 1
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of LY6A mRNA trichostatin A inhibits the reaction [Nickel affects the expression of LY6A mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 7:108,892,342...108,898,892
Ensembl chr 7:108,892,339...108,895,989
|
|
| G
|
Ly6d
|
lymphocyte antigen 6 family member D
|
increases expression
|
ISO
|
Nickel results in increased expression of LY6D mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:108,532,207...108,533,943
Ensembl chr 7:108,532,215...108,533,716
|
|
| G
|
Ly86
|
lymphocyte antigen 86
|
increases expression
|
ISO
|
Nickel results in increased expression of LY86 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr17:27,621,313...27,705,336
Ensembl chr17:27,621,313...27,692,743
|
|
| G
|
Ly9
|
lymphocyte antigen 9
|
increases expression
|
ISO
|
Nickel results in increased expression of LY9 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:86,610,762...86,633,314
Ensembl chr13:86,611,784...86,657,293
|
|
| G
|
Lyar
|
Ly1 antibody reactive
|
increases expression
|
ISO
|
Nickel results in increased expression of LYAR mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:76,789,193...76,802,973
Ensembl chr14:76,789,200...76,802,765
|
|
| G
|
Lyn
|
LYN proto-oncogene, Src family tyrosine kinase
|
increases expression
|
ISO
|
Nickel results in increased expression of LYN mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:21,437,127...21,553,097
Ensembl chr 5:21,437,084...21,554,461
|
|
| G
|
Lypd1
|
Ly6/Plaur domain containing 1
|
increases expression
|
ISO
|
Nickel results in increased expression of LYPD1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:39,874,937...39,922,385
Ensembl chr13:39,879,096...39,922,338
|
|
| G
|
Lypd6
|
Ly6/Plaur domain containing 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LYPD6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:54,896,618...55,041,928
Ensembl chr 3:54,896,575...55,041,929
|
|
| G
|
Lyplal1
|
lysophospholipase-like 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LYPLAL1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:100,158,060...100,189,339
Ensembl chr13:100,158,060...100,189,503
|
|
| G
|
Lysmd2
|
LysM domain containing 2
|
increases expression
|
ISO
|
Nickel results in increased expression of LYSMD2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:85,259,443...85,274,876
Ensembl chr 8:85,259,410...85,275,241
|
|
| G
|
Lyst
|
lysosomal trafficking regulator
|
decreases expression
|
ISO
|
Nickel results in decreased expression of LYST mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr17:93,225,509...93,427,650
Ensembl chr17:93,225,540...93,427,650
|
|
| G
|
Lyz2
|
lysozyme 2
|
increases expression
|
ISO
|
Nickel results in increased expression of LYZ mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:54,792,715...54,798,060
Ensembl chr 7:54,792,716...54,798,011
|
|
| G
|
M6pr
|
mannose-6-phosphate receptor, cation dependent
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of M6PR mRNA Nickel results in increased expression of M6PR mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 4:157,173,154...157,182,293
Ensembl chr 4:157,173,125...157,182,277
|
|
| G
|
Macrod1
|
mono-ADP ribosylhydrolase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MACROD1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:213,675,413...213,831,571
Ensembl chr 1:213,675,406...213,816,348
|
|
| G
|
Macrod2
|
mono-ADP ribosylhydrolase 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MACROD2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:148,173,821...150,191,077
Ensembl chr 3:148,173,829...150,188,058
|
|
| G
|
Mad2l1
|
mitotic arrest deficient 2 like 1
|
increases expression
|
ISO
|
Nickel results in increased expression of MAD2L1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:97,236,419...97,247,603
Ensembl chr 4:97,236,503...97,243,222
|
|
| G
|
Mad2l2
|
mitotic arrest deficient 2 like 2
|
increases expression
|
ISO
|
Nickel results in increased expression of MAD2L2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:163,846,678...163,859,851
Ensembl chr 5:163,846,687...163,859,851
|
|
| G
|
Mafb
|
MAF bZIP transcription factor B
|
multiple interactions affects expression
|
ISO
|
trichostatin A inhibits the reaction [Nickel affects the expression of MAFB mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 3:169,417,890...169,419,810
Ensembl chr 3:169,416,945...169,419,975
|
|
| G
|
Magi1
|
membrane associated guanylate kinase, WW and PDZ domain containing 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MAGI1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:127,762,590...128,368,228
Ensembl chr 4:127,762,590...128,367,833
|
|
| G
|
Magi2
|
membrane associated guanylate kinase, WW and PDZ domain containing 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MAGI2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:15,278,518...16,762,427
Ensembl chr 4:15,278,518...16,762,199
|
|
| G
|
Magohb
|
mago homolog B, exon junction complex subunit
|
increases expression
|
ISO
|
Nickel results in increased expression of MAGOHB mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:166,765,558...166,773,406
Ensembl chr 4:166,765,618...166,773,851
|
|
| G
|
Mal
|
mal, T-cell differentiation protein
|
increases expression
|
ISO
|
Nickel results in increased expression of MAL mRNA
|
CTD |
PMID:12540486 PMID:24768652 |
|
NCBI chr 3:135,317,664...135,341,423
Ensembl chr 3:135,317,664...135,341,423
|
|
| G
|
Mamdc2
|
MAM domain containing 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MAMDC2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:230,290,482...230,443,014
Ensembl chr 1:230,290,499...230,442,711
|
|
| G
|
Maml2
|
mastermind-like transcriptional coactivator 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MAML2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:18,552,480...18,869,923
Ensembl chr 8:18,552,281...18,869,900
|
|
| G
|
Maml3
|
mastermind-like transcriptional coactivator 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MAML3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:137,871,267...138,288,615
Ensembl chr 2:137,871,267...138,287,960
|
|
| G
|
Man2a1
|
mannosidase, alpha, class 2A, member 1
|
increases expression
|
ISO
|
Nickel results in increased expression of MAN2A1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:111,698,913...111,855,257
Ensembl chr 9:111,698,913...111,867,850
|
|
| G
|
Manea
|
mannosidase, endo-alpha
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MANEA mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:44,992,937...45,015,084
Ensembl chr 5:44,992,937...45,015,084
|
|
| G
|
Maoa
|
monoamine oxidase A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MAOA mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr X:8,615,239...8,681,372
Ensembl chr X:8,615,239...8,682,631
|
|
| G
|
Map1lc3a
|
microtubule-associated protein 1 light chain 3 alpha
|
decreases expression multiple interactions
|
ISO
|
Nickel results in decreased expression of MAP1LC3A mRNA 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Melatonin inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of MAP1LC3A mRNA]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of MAP1LC3A mRNA]; [nickel chloride results in increased abundance of Nickel] which results in increased expression of MAP1LC3A mRNA; Melatonin inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of MAP1LC3A mRNA]
|
CTD |
PMID:24768652 PMID:25583101 PMID:35568058 |
|
NCBI chr 3:164,243,204...164,244,850
Ensembl chr 3:164,243,093...164,244,850
|
|
| G
|
Map3k14
|
mitogen-activated protein kinase kinase kinase 14
|
increases expression
|
ISO
|
Nickel results in increased expression of MAP3K14 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:88,665,417...88,715,669
Ensembl chr10:88,665,417...88,715,592
|
|
| G
|
Map3k20
|
mitogen-activated protein kinase kinase kinase 20
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MAP3K20 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:77,538,146...77,697,540
Ensembl chr 3:77,537,956...77,697,538
|
|
| G
|
Map4k1
|
mitogen activated protein kinase kinase kinase kinase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of MAP4K1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:93,398,460...93,419,996
Ensembl chr 1:93,398,454...93,419,993
|
|
| G
|
Map4k2
|
mitogen activated protein kinase kinase kinase kinase 2
|
multiple interactions affects expression
|
ISO
|
trichostatin A inhibits the reaction [Nickel affects the expression of MAP4K2 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 1:213,074,360...213,090,042
Ensembl chr 1:213,074,377...213,096,987
|
|
| G
|
Map4k4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
increases expression
|
ISO
|
Nickel results in increased expression of MAP4K4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 9:49,696,573...49,822,353
Ensembl chr 9:49,696,700...49,822,353
|
|
| G
|
Map6
|
microtubule-associated protein 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MAP6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:162,980,339...163,046,548
Ensembl chr 1:162,980,181...163,046,548
|
|
| G
|
Mapk1
|
mitogen activated protein kinase 1
|
multiple interactions increases expression increases phosphorylation
|
ISO EXP
|
[nickel chloride results in increased abundance of Nickel] which results in increased phosphorylation of MAPK1 protein; chromium hexavalent ion inhibits the reaction [Nickel results in increased phosphorylation of MAPK1 protein]; KDM3A mRNA affects the reaction [Nickel results in increased phosphorylation of MAPK1 protein]; KDM3A protein inhibits the reaction [Nickel results in increased phosphorylation of MAPK1 protein]; SPRY2 mRNA affects the reaction [Nickel results in increased phosphorylation of MAPK1 protein]; SPRY2 protein inhibits the reaction [Nickel results in increased phosphorylation of MAPK1 protein] Nickel results in increased expression of MAPK1 mRNA 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Nickel analog promotes the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein]]; Acetylcysteine inhibits the reaction [Nickel analog promotes the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein]]; Nickel analog promotes the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein]
|
CTD |
PMID:17045426 PMID:19403854 PMID:20881000 PMID:22700867 PMID:24768652 PMID:25583101 PMID:30724446 More...
|
|
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
|
|
| G
|
Mapk10
|
mitogen activated protein kinase 10
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MAPK10 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr14:6,802,247...7,094,103
Ensembl chr14:6,802,295...7,094,100
|
|
| G
|
Mapk13
|
mitogen activated protein kinase 13
|
increases expression
|
ISO
|
Nickel results in increased expression of MAPK13 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr20:6,836,979...6,847,197
Ensembl chr20:6,837,013...6,847,191
|
|
| G
|
Mapk14
|
mitogen activated protein kinase 14
|
decreases expression multiple interactions
|
ISO EXP
|
Nickel results in decreased expression of MAPK14 mRNA [nickel sulfate results in increased abundance of Nickel] which results in decreased expression of MAPK14 mRNA
|
CTD |
PMID:23195993 PMID:31734292 |
|
NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294
|
|
| G
|
Mapk3
|
mitogen activated protein kinase 3
|
multiple interactions increases phosphorylation
|
ISO EXP
|
[nickel chloride results in increased abundance of Nickel] which results in increased phosphorylation of MAPK3 protein; chromium hexavalent ion inhibits the reaction [Nickel results in increased phosphorylation of MAPK3 protein]; KDM3A mRNA affects the reaction [Nickel results in increased phosphorylation of MAPK3 protein]; KDM3A protein inhibits the reaction [Nickel results in increased phosphorylation of MAPK3 protein]; SPRY2 mRNA affects the reaction [Nickel results in increased phosphorylation of MAPK3 protein]; SPRY2 protein inhibits the reaction [Nickel results in increased phosphorylation of MAPK3 protein] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Nickel analog promotes the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein]]; Acetylcysteine inhibits the reaction [Nickel analog promotes the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein]]; Nickel analog promotes the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein]
|
CTD |
PMID:17045426 PMID:19403854 PMID:20881000 PMID:22700867 PMID:30724446 |
|
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
|
|
| G
|
Mapk6
|
mitogen-activated protein kinase 6
|
increases expression
|
ISO
|
Nickel results in increased expression of MAPK6 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 8:85,027,141...85,050,236
Ensembl chr 8:85,027,144...85,050,236
|
|
| G
|
Mapkapk3
|
MAPK activated protein kinase 3
|
increases expression
|
ISO
|
Nickel results in increased expression of MAPKAPK3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:116,808,429...116,842,228
Ensembl chr 8:116,808,429...116,842,228
|
|
| G
|
Mapre1
|
microtubule-associated protein, RP/EB family, member 1
|
increases expression
|
ISO
|
Nickel results in increased expression of MAPRE1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:162,679,020...162,707,167
Ensembl chr 3:162,673,195...162,711,210
|
|
| G
|
Mapt
|
microtubule-associated protein tau
|
decreases expression increases response to substance multiple interactions
|
ISO
|
Nickel results in decreased expression of MAPT mRNA MAPT protein mutant form results in increased susceptibility to Nickel Nickel results in increased expression of and results in increased phosphorylation of MAPT protein
|
CTD |
PMID:12540486 PMID:24768652 PMID:25583101 PMID:31953414 |
|
NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,638,599...89,736,108
|
|
| G
|
Marchf1
|
membrane associated ring-CH-type finger 1
|
increases expression
|
ISO
|
Nickel results in increased expression of MARCHF1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr16:28,022,159...28,880,872
Ensembl chr16:28,022,159...28,881,054
|
|
| G
|
Marchf2
|
membrane associated ring-CH-type finger 2
|
multiple interactions
|
ISO
|
MT1 affects the reaction [Nickel affects the expression of MARCHF2 mRNA]; MT2 affects the reaction [Nickel affects the expression of MARCHF2 mRNA]
|
CTD |
PMID:16166738 |
|
NCBI chr 7:15,183,931...15,209,988
Ensembl chr 7:15,183,925...15,202,002
|
|
| G
|
Marcks
|
myristoylated alanine rich protein kinase C substrate
|
increases expression
|
ISO
|
Nickel results in increased expression of MARCKS mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr20:42,240,185...42,245,882
Ensembl chr20:42,240,185...42,245,882
|
|
| G
|
Mark1
|
microtubule affinity regulating kinase 1
|
affects expression decreases expression multiple interactions
|
ISO
|
Nickel affects the expression of MARK1 mRNA Nickel results in decreased expression of MARK1 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of MARK1 mRNA]
|
CTD |
PMID:14575637 PMID:25583101 |
|
NCBI chr13:98,981,727...99,086,998
Ensembl chr13:98,983,020...99,086,701
|
|
| G
|
Mark2
|
microtubule affinity regulating kinase 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MARK2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 1:213,890,213...213,955,417
Ensembl chr 1:213,890,213...213,955,149
|
|
| G
|
Mars1
|
methionyl-tRNA synthetase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of MARS1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:65,006,456...65,023,880
Ensembl chr 7:64,998,544...65,023,753
|
|
| G
|
Mat2a
|
methionine adenosyltransferase 2A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MAT2A mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 4:106,048,043...106,053,612
Ensembl chr 4:106,038,254...106,053,645
|
|
| G
|
Mat2b
|
methionine adenosyltransferase 2 non-catalytic beta subunit
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MAT2B mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr10:25,609,202...25,626,694
Ensembl chr10:25,609,204...25,625,176
|
|
| G
|
Matn2
|
matrilin 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MATN2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:67,380,140...67,529,767
Ensembl chr 7:67,380,168...67,530,153
|
|
| G
|
Matn3
|
matrilin 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MATN3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:37,467,729...37,487,776
Ensembl chr 6:37,467,729...37,487,776
|
|
| G
|
Mb
|
myoglobin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MB mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:110,640,511...110,647,742
Ensembl chr 7:110,640,512...110,647,958
|
|
| G
|
Mboat2
|
membrane bound O-acyltransferase domain containing 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MBOAT2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 6:47,199,751...47,326,215
Ensembl chr 6:47,199,774...47,326,208
|
|
| G
|
Mbp
|
myelin basic protein
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MBP mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr18:78,130,652...78,241,174
Ensembl chr18:78,130,325...78,241,174
|
|
| G
|
Mcf2l
|
MCF.2 cell line derived transforming sequence-like
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MCF2L mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr16:83,209,277...83,355,683
Ensembl chr16:83,209,280...83,354,956
|
|
| G
|
Mcl1
|
MCL1 apoptosis regulator, BCL2 family member
|
increases expression
|
ISO
|
Nickel results in increased expression of MCL1 mRNA
|
CTD |
PMID:12540486 PMID:24768652 PMID:25583101 |
|
NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:185,908,168...185,938,782
|
|
| G
|
Mcm10
|
minichromosome maintenance 10 replication initiation factor
|
increases expression
|
ISO
|
Nickel results in increased expression of MCM10 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr17:78,172,049...78,197,644
Ensembl chr17:78,175,398...78,197,636
|
|
| G
|
Mcm2
|
minichromosome maintenance complex component 2
|
increases expression
|
ISO
|
Nickel results in increased expression of MCM2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:122,903,679...122,918,205
Ensembl chr 4:122,903,682...122,918,094
|
|
| G
|
Mcm3
|
minichromosome maintenance complex component 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MCM3 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 9:30,715,602...30,733,746
Ensembl chr 9:30,715,602...30,733,746
|
|
| G
|
Mcm5
|
minichromosome maintenance complex component 5
|
increases expression
|
ISO
|
Nickel results in increased expression of MCM5 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr19:13,488,813...13,510,131
Ensembl chr19:13,488,813...13,517,758
|
|
| G
|
Mcm6
|
minichromosome maintenance complex component 6
|
increases expression
|
ISO
|
Nickel results in increased expression of MCM6 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:42,379,161...42,404,352
Ensembl chr13:42,379,162...42,465,467
|
|
| G
|
Mcm7
|
minichromosome maintenance complex component 7
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of MCM7 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of MCM7 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr12:22,155,921...22,163,320
Ensembl chr12:22,155,921...22,163,771
|
|
| G
|
Mcmbp
|
minichromosome maintenance complex binding protein
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of MCMBP mRNA Nickel results in increased expression of MCMBP mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr 1:192,702,383...192,747,381
Ensembl chr 1:192,702,385...192,755,975
|
|
| G
|
Mcoln3
|
mucolipin TRP cation channel 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MCOLN3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:237,596,544...237,705,770
Ensembl chr 2:237,626,302...237,705,769
|
|
| G
|
Mctp2
|
multiple C2 and transmembrane domain containing 2
|
increases expression
|
ISO
|
Nickel results in increased expression of MCTP2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:135,179,845...135,412,798
Ensembl chr 1:135,179,845...135,412,694
|
|
| G
|
Mcub
|
mitochondrial calcium uniporter dominant negative subunit beta
|
increases expression
|
ISO
|
Nickel results in increased expression of MCUB mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:221,153,525...221,223,814
Ensembl chr 2:221,153,525...221,223,814
|
|
| G
|
Mdc1
|
mediator of DNA damage checkpoint 1
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of MDC1 mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr20:2,898,496...2,914,960
Ensembl chr20:2,900,308...2,914,960
|
|
| G
|
Mdfi
|
MyoD family inhibitor
|
increases expression
|
ISO
|
Nickel results in increased expression of MDFI mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:20,654,359...20,672,768
Ensembl chr 9:20,654,417...20,672,767
|
|
| G
|
Mdm2
|
MDM2 proto-oncogene
|
increases expression multiple interactions
|
ISO
|
Nickel results in increased expression of MDM2 mRNA TP53 protein affects the reaction [Nickel results in increased expression of MDM2 mRNA]
|
CTD |
PMID:24068677 |
|
NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791
|
|
| G
|
Mdm4
|
MDM4 regulator of p53
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MDM4 protein
|
CTD |
PMID:24068677 |
|
NCBI chr13:46,922,236...47,068,241
Ensembl chr13:46,958,298...47,026,372
|
|
| G
|
Me2
|
malic enzyme 2
|
increases expression
|
ISO
|
Nickel results in increased expression of ME2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr18:69,626,073...69,676,218
Ensembl chr18:69,626,087...69,676,218
|
|
| G
|
Med11
|
mediator complex subunit 11
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MED11 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr10:55,662,956...55,664,574
Ensembl chr10:55,663,001...55,664,765
|
|
| G
|
Med12l
|
mediator complex subunit 12L
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of MED12L mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr 2:145,403,318...145,726,317
Ensembl chr 2:145,404,375...145,723,516
|
|
| G
|
Med20
|
mediator complex subunit 20
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MED20 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 9:20,867,681...20,880,288
Ensembl chr 9:20,867,681...20,880,011
|
|
| G
|
Medag
|
mesenteric estrogen-dependent adipogenesis
|
increases expression
|
ISO
|
Nickel results in increased expression of MEDAG mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr12:10,649,526...10,670,913
Ensembl chr12:10,649,526...10,692,756
|
|
| G
|
Mef2a
|
myocyte enhancer factor 2a
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of MEF2A mRNA trichostatin A inhibits the reaction [Nickel affects the expression of MEF2A mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 1:130,258,083...130,392,819
Ensembl chr 1:130,260,339...130,392,162
|
|
| G
|
Mef2c
|
myocyte enhancer factor 2C
|
increases expression
|
ISO
|
Nickel results in increased expression of MEF2C mRNA
|
CTD |
PMID:18922574 |
|
NCBI chr 2:15,708,732...15,871,639
Ensembl chr 2:15,708,924...15,871,640
|
|
| G
|
Mefv
|
MEFV innate immunity regulator, pyrin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MEFV mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr10:12,288,514...12,303,337
Ensembl chr10:12,293,782...12,303,333
|
|
| G
|
Megf10
|
multiple EGF-like domains 10
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MEGF10 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr18:52,803,292...52,953,431
Ensembl chr18:52,847,781...52,950,675
|
|
| G
|
Megf6
|
multiple EGF-like-domains 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MEGF6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:170,020,699...170,121,557
Ensembl chr 5:170,020,778...170,121,554
|
|
| G
|
Megf9
|
multiple EGF-like-domains 9
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MEGF9 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 5:89,008,679...89,120,731
Ensembl chr 5:89,008,679...89,120,731
|
|
| G
|
Meis1
|
Meis homeobox 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MEIS1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr14:97,356,949...97,499,646
Ensembl chr14:97,322,748...97,495,083
|
|
| G
|
Meis2
|
Meis homeobox 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MEIS2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:123,197,066...123,399,002
Ensembl chr 3:123,197,066...123,397,751
|
|
| G
|
Melk
|
maternal embryonic leucine zipper kinase
|
increases expression
|
ISO
|
Nickel results in increased expression of MELK mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:63,336,151...63,396,254
Ensembl chr 5:63,336,106...63,396,247
|
|
| G
|
Meltf
|
melanotransferrin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MELTF mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:82,389,420...82,411,270
Ensembl chr11:82,389,420...82,411,270
|
|
| G
|
Meox2
|
mesenchyme homeobox 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MEOX2 mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr 6:59,584,025...59,644,722
Ensembl chr 6:59,583,785...59,644,700
|
|
| G
|
Mertk
|
MER proto-oncogene, tyrosine kinase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MERTK mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:136,391,936...136,498,366
Ensembl chr 3:136,383,560...136,500,192
|
|
| G
|
Mettl1
|
methyltransferase 1, tRNA methylguanosine
|
increases expression
|
ISO
|
Nickel results in increased expression of METTL1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:64,750,189...64,754,531
Ensembl chr 7:64,750,198...64,754,639
|
|
| G
|
Mettl13
|
methyltransferase 13, eEF1A N-terminus and K55
|
decreases expression
|
ISO
|
Nickel results in decreased expression of METTL13 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr13:77,419,393...77,433,228
Ensembl chr13:77,419,397...77,433,104
|
|
| G
|
Mettl6
|
methyltransferase 6, tRNA N3-cytidine
|
decreases expression
|
ISO
|
Nickel results in decreased expression of METTL6 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr16:6,667,971...6,705,385
Ensembl chr16:6,689,248...6,705,359
|
|
| G
|
Mfap3l
|
microfibril associated protein 3 like
|
increases expression decreases expression
|
ISO
|
Nickel results in increased expression of MFAP3L mRNA Nickel results in decreased expression of MFAP3L mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr16:34,422,490...34,465,544
Ensembl chr16:34,426,696...34,441,709
|
|
| G
|
Mfap4
|
microfibril associated protein 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MFAP4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:46,666,552...46,669,613
Ensembl chr10:46,655,722...46,669,740
|
|
| G
|
Mfhas1
|
multifunctional ROCO family signaling regulator 1
|
increases expression
|
ISO
|
Nickel results in increased expression of MFHAS1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr16:63,248,833...63,336,441
Ensembl chr16:63,250,455...63,336,602
|
|
| G
|
Mfn1
|
mitofusin 1
|
multiple interactions
|
ISO
|
[nickel chloride results in increased abundance of Nickel] which results in decreased expression of MFN1 mRNA
|
CTD |
PMID:36794572 |
|
NCBI chr 2:117,240,525...117,288,017
Ensembl chr 2:117,241,759...117,290,190
|
|
| G
|
Mfn2
|
mitofusin 2
|
multiple interactions
|
ISO
|
[nickel chloride results in increased abundance of Nickel] which results in decreased expression of MFN2 mRNA; [nickel chloride results in increased abundance of Nickel] which results in decreased expression of MFN2 protein
|
CTD |
PMID:36794572 |
|
NCBI chr 5:163,587,463...163,617,363
Ensembl chr 5:163,587,463...163,618,495
|
|
| G
|
Mfng
|
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
increases expression
|
ISO
|
Nickel results in increased expression of MFNG mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:112,191,288...112,209,129
Ensembl chr 7:112,161,071...112,209,129
|
|
| G
|
Mfsd14a
|
major facilitator superfamily domain containing 14A
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC71A1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 2:207,264,081...207,305,880
Ensembl chr 2:207,264,941...207,296,505
|
|
| G
|
Mfsd14b
|
major facilitator superfamily domain containing 14B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLC71A2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr17:83,686...136,623
Ensembl chr17:83,762...136,514
|
|
| G
|
Mfsd2a
|
MFSD2 lysolipid transporter A, lysophospholipid
|
increases expression
|
ISO
|
Nickel results in increased expression of MFSD2A mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr 5:140,510,933...140,525,828
Ensembl chr 5:140,510,953...140,525,916
|
|
| G
|
Mfsd4a
|
major facilitator superfamily domain containing 4A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLC60A1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:46,015,321...46,062,633
Ensembl chr13:46,021,659...46,062,633
|
|
| G
|
Mgat2
|
alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
|
increases expression
|
ISO
|
Nickel results in increased expression of MGAT2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:93,392,416...93,394,905
Ensembl chr 6:93,390,555...93,395,176
|
|
| G
|
Mgat4a
|
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A
|
increases expression
|
ISO
|
Nickel results in increased expression of MGAT4A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:47,169,229...47,282,577
Ensembl chr 9:47,169,232...47,282,574
|
|
| G
|
Mgme1
|
mitochondrial genome maintenance exonuclease 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MGME1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 3:152,094,514...152,103,314
Ensembl chr 3:152,094,658...152,103,313
|
|
| G
|
Mgp
|
matrix Gla protein
|
multiple interactions decreases expression affects expression
|
ISO
|
trichostatin A inhibits the reaction [Nickel affects the expression of MGP mRNA] Nickel results in decreased expression of MGP mRNA
|
CTD |
PMID:14575637 PMID:24768652 PMID:25583101 |
|
NCBI chr 4:171,497,472...171,500,888
Ensembl chr 4:171,497,471...171,500,859
|
|
| G
|
Mgst1
|
microsomal glutathione S-transferase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MGST1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:172,760,930...172,776,157
Ensembl chr 4:172,760,886...172,776,875
|
|
| G
|
Mgst2
|
microsomal glutathione S-transferase 2
|
decreases expression
|
EXP
|
Nickel results in decreased expression of MGST2 mRNA
|
CTD |
PMID:19440498 |
|
NCBI chr 2:137,821,787...137,866,664
Ensembl chr 2:137,836,140...137,866,661
|
|
| G
|
Mgst3
|
microsomal glutathione S-transferase 3
|
affects expression
|
EXP
|
Nickel affects the expression of MGST3 mRNA
|
CTD |
PMID:19440498 |
|
NCBI chr13:82,059,480...82,080,418
Ensembl chr13:82,059,480...82,080,575
|
|
| G
|
Mical1
|
microtubule associated monooxygenase, calponin and LIM domain containing 1
|
increases expression
|
ISO
|
Nickel results in increased expression of MICAL1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr20:46,547,983...46,568,487
Ensembl chr20:46,556,536...46,568,487
|
|
| G
|
Micb
|
MHC class I polypeptide-related sequence B
|
increases expression
|
ISO
|
Nickel results in increased expression of MICB mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:87,623,826...87,641,075
Ensembl chr 1:87,623,826...87,640,872
|
|
| G
|
Micu3
|
mitochondrial calcium uptake family, member 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MICU3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr16:58,624,702...58,714,302
Ensembl chr16:58,629,208...58,714,045
|
|
| G
|
Mid1
|
midline 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MID1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:27,678,248...28,053,049
Ensembl chr X:27,681,867...27,906,105
|
|
| G
|
Mid2
|
midline 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MID2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:109,143,057...109,245,257
Ensembl chr X:109,143,253...109,245,255
|
|
| G
|
Mif
|
macrophage migration inhibitory factor
|
multiple interactions
|
EXP
|
[Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of MIF mRNA
|
CTD |
PMID:22198552 |
|
NCBI chr20:12,767,138...12,791,222
Ensembl chr 4:134,041,774...134,042,121 Ensembl chr20:134,041,774...134,042,121
|
|
| G
|
Minpp1
|
multiple inositol-polyphosphate phosphatase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MINPP1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 1:239,766,809...239,793,023
Ensembl chr 1:239,767,286...239,793,015
|
|
| G
|
Mir125b1
|
microRNA 125b-1
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of MIR125B1 mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr 8:50,850,036...50,850,122
Ensembl chr 8:50,850,036...50,850,122
|
|
| G
|
Mir130b
|
microRNA 130b
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of MIR130B mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr11:97,384,380...97,384,461
Ensembl chr11:97,384,380...97,384,461
|
|
| G
|
Mir132
|
microRNA 132
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of MIR132 mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr10:60,522,033...60,522,133
Ensembl chr10:60,522,033...60,522,133
|
|
| G
|
Mir133b
|
microRNA 133b
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of MIR133B mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr 9:30,594,582...30,594,665
Ensembl chr 9:30,594,582...30,594,665
|
|
| G
|
Mir139
|
microRNA 139
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of MIR139 mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr 1:165,290,859...165,290,926
Ensembl chr 1:165,290,856...165,290,933
|
|
| G
|
Mir147
|
microRNA 147
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of MIR147 mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr 3:130,176,275...130,176,353
Ensembl chr 3:130,176,275...130,176,353
|
|
| G
|
Mir154
|
microRNA 154
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of MIR154 mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr 6:134,574,352...134,574,435
Ensembl chr 6:134,574,352...134,574,435
|
|
| G
|
Mir155hg
|
Mir155 host gene
|
increases expression
|
ISO
|
Nickel results in increased expression of MIR155HG mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr11:37,259,928...37,262,157
|
|
| G
|
Mir181b1
|
microRNA 181b-1
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of MIR181B1 mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr13:52,037,228...52,037,337
Ensembl chr13:52,037,228...52,037,337
|
|
| G
|
Mir196b
|
microRNA 196b
|
multiple interactions
|
ISO
|
[Air Pollutants, Occupational results in increased abundance of Nickel] which results in increased expression of MIR196B mRNA
|
CTD |
PMID:27506416 |
|
NCBI chr 4:82,661,101...82,661,185
|
|
| G
|
Mir21
|
microRNA 21
|
increases expression
|
ISO
|
Nickel results in increased expression of MIR21 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr10:71,902,600...71,902,691
|
|
| G
|
Mir210
|
microRNA 210
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of MIR210 mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr 1:205,755,923...205,756,032
Ensembl chr 1:205,755,917...205,756,034
|
|
| G
|
Mir212
|
microRNA 212
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of MIR212 mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr10:60,521,740...60,521,850
Ensembl chr10:60,521,740...60,521,850
|
|
| G
|
Mir214
|
microRNA 214
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MIR214 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:77,121,645...77,121,752
Ensembl chr13:77,121,643...77,121,752
|
|
| G
|
Mir23b
|
microRNA 23b
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of MIR23B mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr17:1,819,386...1,819,482
|
|
| G
|
Mir27a
|
microRNA 27a
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of MIR27A mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr19:40,859,603...40,859,689
|
|
| G
|
Mir3074
|
microRNA 3074
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of MIR3074 mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr17:1,818,648...1,818,764
Ensembl chr17:1,818,648...1,818,764
|
|
| G
|
Mir3120
|
microRNA 3120
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of MIR3120 mRNA; [nickel sulfate results in increased abundance of Nickel] which results in increased expression of MIR3120 mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr13:77,121,647...77,121,763
Ensembl chr13:77,121,643...77,121,752
|
|
| G
|
Mir32
|
microRNA 32
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of MIR32 mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr 5:76,391,285...76,391,354
|
|
| G
|
Mir320a
|
microRNA 320a
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of MIR320A mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr15:51,926,088...51,926,169
Ensembl chr15:51,926,088...51,926,169
|
|
| G
|
Mir322
|
microRNA 322
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of MIR322 mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr X:137,726,147...137,726,241
|
|
| G
|
Mir376b
|
microRNA 376b
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of MIR376B mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr 6:134,558,861...134,558,946
Ensembl chr 6:134,558,861...134,558,946
|
|
| G
|
Mir503
|
microRNA 503
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of MIR503 mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr X:137,725,856...137,725,926
|
|
| G
|
Mir708
|
microRNA 708
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of MIR708 mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr 1:160,011,158...160,011,245
Ensembl chr 1:160,011,158...160,011,245
|
|
| G
|
Mir760
|
microRNA 760
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of MIR760 mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr 2:213,077,269...213,077,348
|
|
| G
|
Mirlet7c-1
|
microRNA let-7c
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of MIRLET7C-1 mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr11:29,688,112...29,688,205
Ensembl chr11:29,688,107...29,688,214
|
|
| G
|
Mitf
|
melanocyte inducing transcription factor
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MITF mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:131,965,676...132,177,790
Ensembl chr 4:131,965,714...132,177,790
|
|
| G
|
Mki67
|
marker of proliferation Ki-67
|
increases expression
|
ISO
|
Nickel results in increased expression of MKI67 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593
|
|
| G
|
Mkks
|
MKKS centrosomal shuttling protein
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MKKS mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 3:144,654,563...144,672,831
Ensembl chr 3:144,654,566...144,672,831
|
|
| G
|
Mkrn3
|
makorin, ring finger protein, 3
|
increases expression
|
ISO
|
Nickel results in increased expression of MKRN3 mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr 1:125,338,664...125,341,178
Ensembl chr 1:125,338,564...125,341,164
|
|
| G
|
Mkx
|
mohawk homeobox
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MKX mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr17:59,772,113...59,851,160
Ensembl chr17:59,773,570...59,850,345
|
|
| G
|
Mlf1
|
myeloid leukemia factor 1
|
increases expression
|
ISO
|
Nickel results in increased expression of MLF1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 2:153,958,060...153,991,705
Ensembl chr 2:153,958,546...153,994,220
|
|
| G
|
Mlh1
|
mutL homolog 1
|
increases expression
|
ISO
|
Nickel analog results in increased expression of MLH1 mRNA; Nickel analog results in increased expression of MLH1 protein
|
CTD |
PMID:24579805 |
|
NCBI chr 8:120,074,871...120,112,109
Ensembl chr 8:120,065,900...120,112,011
|
|
| G
|
Mlkl
|
mixed lineage kinase domain like pseudokinase
|
increases expression
|
ISO
|
Nickel results in increased expression of MLKL mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr19:56,186,860...56,213,886
Ensembl chr19:56,186,860...56,213,858
|
|
| G
|
Mlph
|
melanophilin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MLPH mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:98,955,036...98,990,566
Ensembl chr 9:98,955,141...98,990,556
|
|
| G
|
Mmaa
|
metabolism of cobalamin associated A
|
increases expression
|
ISO
|
Nickel results in increased expression of MMAA mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr19:45,523,352...45,553,602
Ensembl chr19:45,523,379...45,555,375
|
|
| G
|
Mmp1
|
matrix metallopeptidase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of MMP1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:12,943,453...12,963,964
|
|
| G
|
Mmp10
|
matrix metallopeptidase 10
|
increases expression
|
ISO
|
Nickel results in increased expression of MMP10 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:12,974,707...12,982,613
Ensembl chr 8:12,974,707...12,982,613
|
|
| G
|
Mmp12
|
matrix metallopeptidase 12
|
affects expression increases expression multiple interactions
|
ISO
|
Nickel affects the expression of MMP12 mRNA Nickel results in increased expression of MMP12 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of MMP12 mRNA]
|
CTD |
PMID:14575637 PMID:25583101 |
|
NCBI chr 8:12,866,652...12,876,554
Ensembl chr 8:12,866,641...12,884,478
|
|
| G
|
Mmp13
|
matrix metallopeptidase 13
|
multiple interactions
|
ISO
|
[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of MMP13 mRNA; TNF protein promotes the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of MMP13 mRNA]
|
CTD |
PMID:23503329 |
|
NCBI chr 8:12,782,829...12,793,108
Ensembl chr 8:12,782,813...12,793,105
|
|
| G
|
Mmp19
|
matrix metallopeptidase 19
|
increases expression
|
ISO
|
Nickel results in increased expression of MMP19 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:1,805,732...1,814,054
Ensembl chr 7:1,805,860...1,814,863
|
|
| G
|
Mmp2
|
matrix metallopeptidase 2
|
increases activity increases expression multiple interactions
|
ISO
|
Nickel results in increased activity of MMP2 protein Nickel results in increased expression of MMP2 mRNA; Nickel results in increased expression of MMP2 protein tanespimycin affects the reaction [Nickel results in increased activity of MMP2 protein]; tanespimycin inhibits the reaction [Nickel results in increased expression of MMP2 mRNA]
|
CTD |
PMID:16581223 PMID:21401309 PMID:24840272 |
|
NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856
|
|
| G
|
Mmp27
|
matrix metallopeptidase 27
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MMP27 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 8:13,030,752...13,040,671
Ensembl chr 8:13,030,746...13,040,671
|
|
| G
|
Mmp3
|
matrix metallopeptidase 3
|
multiple interactions increases expression
|
ISO
|
[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of MMP3 mRNA; TNF protein inhibits the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of MMP3 mRNA] Nickel results in increased expression of MMP3 mRNA
|
CTD |
PMID:23503329 PMID:25583101 |
|
NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:12,925,280...12,938,826
|
|
| G
|
Mmp9
|
matrix metallopeptidase 9
|
multiple interactions increases expression increases activity
|
ISO
|
tanespimycin affects the reaction [Nickel results in increased activity of MMP9 protein]; tanespimycin inhibits the reaction [Nickel results in increased expression of MMP9 mRNA] Nickel results in increased expression of MMP9 mRNA; Nickel results in increased expression of MMP9 protein [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of MMP9 mRNA; TNF protein promotes the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of MMP9 mRNA]
|
CTD |
PMID:21401309 PMID:23503329 PMID:24840272 PMID:25583101 |
|
NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
|
|
| G
|
Mnd1
|
meiotic nuclear divisions 1
|
increases expression
|
ISO
|
Nickel results in increased expression of MND1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:171,731,523...171,794,124
Ensembl chr 2:171,731,523...171,794,095
|
|
| G
|
Mnda
|
myeloid cell nuclear differentiation antigen
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of MNDA mRNA Nickel results in increased expression of MNDA mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr13:88,550,224...88,567,892
Ensembl chr13:88,550,228...88,566,537
|
|
| G
|
Mob1a
|
MOB kinase activator 1A
|
increases expression
|
ISO
|
Nickel results in increased expression of MOB1A mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:117,389,278...117,406,255
Ensembl chr 4:117,389,186...117,406,250
|
|
| G
|
Mob3b
|
MOB kinase activator 3B
|
increases expression
|
ISO
|
Nickel results in increased expression of MOB3B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:54,342,509...54,534,164
Ensembl chr 5:54,338,056...54,454,678
|
|
| G
|
Mogat1
|
monoacylglycerol O-acyltransferase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MOGAT1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:87,429,427...87,436,977
Ensembl chr 9:87,405,119...87,436,977
|
|
| G
|
Mogat2
|
monoacylglycerol O-acyltransferase 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MOGAT2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:162,933,964...162,957,896
Ensembl chr 1:162,933,966...162,957,896
|
|
| G
|
Mon2
|
MON2 homolog, regulator of endosome-to-Golgi trafficking
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MON2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:60,534,772...60,613,467
Ensembl chr 7:60,534,772...60,613,467
|
|
| G
|
Morn4
|
MORN repeat containing 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MORN4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:250,837,639...250,847,943
Ensembl chr 1:250,837,643...250,848,026
|
|
| G
|
Mospd2
|
motile sperm domain containing 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MOSPD2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr X:33,052,063...33,105,550
Ensembl chr X:33,052,004...33,107,635
|
|
| G
|
Moxd1
|
monooxygenase, DBH-like 1
|
increases expression
|
ISO
|
Nickel results in increased expression of MOXD1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:22,894,543...22,984,599
Ensembl chr 1:22,894,543...22,984,223
|
|
| G
|
Mpeg1
|
macrophage expressed 1
|
increases expression
|
ISO
|
Nickel results in increased expression of MPEG1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:218,876,848...218,881,364
Ensembl chr 1:218,876,069...218,908,715
|
|
| G
|
Mphosph9
|
M-phase phosphoprotein 9
|
increases expression
|
ISO
|
Nickel results in increased expression of MPHOSPH9 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr12:37,936,442...38,007,053
Ensembl chr12:37,936,885...38,003,348
|
|
| G
|
Mpl
|
MPL proto-oncogene, thrombopoietin receptor
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MPL mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:137,259,288...137,281,540
Ensembl chr 5:137,259,288...137,272,177
|
|
| G
|
Mpo
|
myeloperoxidase
|
multiple interactions
|
EXP
|
[[nickel chloride results in increased abundance of Nickel] co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] results in increased activity of MPO protein; [nickel chloride results in increased abundance of Nickel] which results in increased activity of MPO protein; Fatty Acids, Omega-3 inhibits the reaction [[[nickel chloride results in increased abundance of Nickel] co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] results in increased activity of MPO protein]
|
CTD |
PMID:31639282 |
|
NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056
|
|
| G
|
Mpped2
|
metallophosphoesterase domain containing 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MPPED2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:113,635,614...113,810,307
Ensembl chr 3:113,635,407...113,811,783
|
|
| G
|
Mpz
|
myelin protein zero
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MPZ mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:86,103,290...86,109,156
Ensembl chr13:86,103,290...86,109,155
|
|
| G
|
Mpzl2
|
myelin protein zero-like 2
|
increases expression
|
ISO
|
Nickel results in increased expression of MPZL2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:54,244,920...54,256,064
Ensembl chr 8:54,243,556...54,256,074
|
|
| G
|
Mr1
|
major histocompatibility complex, class I-related
|
increases expression
|
ISO
|
Nickel results in increased expression of MR1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:69,850,420...69,868,302
Ensembl chr13:69,850,420...69,868,502
|
|
| G
|
Mrap
|
melanocortin 2 receptor accessory protein
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MRAP mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:43,477,382...43,489,118
Ensembl chr11:43,478,001...43,489,118
|
|
| G
|
Mrap2
|
melanocortin 2 receptor accessory protein 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MRAP2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:96,968,239...97,024,581
Ensembl chr 8:96,988,079...97,024,579
|
|
| G
|
Mras
|
muscle RAS oncogene homolog
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MRAS mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:108,823,374...108,886,104
Ensembl chr 8:108,823,374...108,875,911
|
|
| G
|
Mrc1
|
mannose receptor, C type 1
|
increases expression
|
ISO
|
Nickel results in increased expression of MRC1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr17:82,157,725...82,239,411
Ensembl chr17:82,157,705...82,239,410
|
|
| G
|
Mrc2
|
mannose receptor, C type 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MRC2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:90,761,751...90,823,055
Ensembl chr10:90,761,878...90,823,055
|
|
| G
|
Mrm3
|
mitochondrial rRNA methyltransferase 3
|
multiple interactions affects expression
|
ISO
|
trichostatin A inhibits the reaction [Nickel affects the expression of MRM3 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr10:61,594,155...61,623,659
Ensembl chr10:61,593,999...61,600,865
|
|
| G
|
Mroh1
|
maestro heat-like repeat family member 1
|
increases expression
|
ISO
|
Nickel results in increased expression of MROH1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:109,979,344...110,052,800
Ensembl chr 7:109,983,337...110,052,801
|
|
| G
|
Mrpl20
|
mitochondrial ribosomal protein L20
|
increases expression
|
ISO
|
Nickel results in increased expression of MRPL20 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:171,690,664...171,695,728
Ensembl chr 5:171,691,198...171,695,728
|
|
| G
|
Mrpl50
|
mitochondrial ribosomal protein L50
|
increases expression
|
ISO
|
Nickel results in increased expression of MRPL50 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:68,662,933...68,668,087
Ensembl chr 5:68,662,939...68,669,748
|
|
| G
|
Mrpl51
|
mitochondrial ribosomal protein L51
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MRPL51 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 4:159,677,988...159,681,650
Ensembl chr 4:159,677,827...159,681,641
|
|
| G
|
Mrps18a
|
mitochondrial ribosomal protein S18A
|
multiple interactions
|
ISO
|
MT1 affects the reaction [Nickel affects the expression of MRPS18A mRNA]; MT2 affects the reaction [Nickel affects the expression of MRPS18A mRNA]
|
CTD |
PMID:16166738 |
|
NCBI chr 9:22,350,887...22,367,380
Ensembl chr 9:22,344,341...22,367,380
|
|
| G
|
Mrps18b
|
mitochondrial ribosomal protein S18B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MRPS18B mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr20:2,842,978...2,849,065
Ensembl chr20:2,842,528...2,849,065
|
|
| G
|
Mrps31
|
mitochondrial ribosomal protein S31
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MRPS31 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr16:76,303,807...76,332,970
Ensembl chr16:76,301,645...76,333,065
|
|
| G
|
Mrtfb
|
myocardin related transcription factor B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MRTFB mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:1,623,887...1,789,658
Ensembl chr10:1,623,940...1,789,658
|
|
| G
|
Mrto4
|
MRT4 homolog, ribosome maturation factor
|
increases expression
|
ISO
|
Nickel results in increased expression of MRTO4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:156,884,985...156,891,738
Ensembl chr 5:156,884,985...156,891,738
|
|
| G
|
Ms4a1
|
membrane spanning 4-domains A1
|
increases expression
|
ISO
|
Nickel results in increased expression of MS4A1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:217,331,274...217,351,934
Ensembl chr 1:217,331,274...217,343,447
|
|
| G
|
Ms4a2
|
membrane spanning 4-domains A2
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of MS4A2 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of MS4A2 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 1:217,864,855...217,873,934
Ensembl chr 1:217,865,159...217,873,108
|
|
| G
|
Ms4a4a
|
membrane spanning 4-domains A4A
|
increases expression
|
ISO
|
Nickel results in increased expression of MS4A4A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:217,495,704...217,510,019
Ensembl chr 1:217,487,996...217,510,503
|
|
| G
|
Ms4a6a
|
membrane spanning 4-domains A6A
|
increases expression
|
ISO
|
Nickel results in increased expression of MS4A6A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:217,826,261...217,839,606
Ensembl chr 1:217,826,261...217,850,013
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| G
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Ms4a7
|
membrane spanning 4-domains A7
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of MS4A7 mRNA Nickel results in increased expression of MS4A7 mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 1:217,394,019...217,409,643
Ensembl chr 1:217,394,019...217,409,643
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| G
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Msh2
|
mutS homolog 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MSH2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:12,567,368...12,626,503
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| G
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Msra
|
methionine sulfoxide reductase A
|
multiple interactions decreases expression
|
ISO
|
[Nickel co-treated with Carbon] results in increased expression of MSRA protein Nickel results in decreased expression of MSRA protein
|
CTD |
PMID:25979628 |
|
NCBI chr15:42,514,818...42,853,278
Ensembl chr15:42,527,045...42,853,279
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| G
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Msrb1
|
methionine sulfoxide reductase B1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MSRB1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr10:14,269,414...14,275,140
Ensembl chr10:14,269,414...14,274,184
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| G
|
Msrb2
|
methionine sulfoxide reductase B2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MSRB2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr17:86,882,750...86,908,392
Ensembl chr17:86,882,394...86,908,391
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| G
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Msrb3
|
methionine sulfoxide reductase B3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MSRB3 mRNA; Nickel results in decreased expression of MSRB3 protein
|
CTD |
PMID:25583101 PMID:25979628 |
|
NCBI chr 7:58,188,827...58,311,459
Ensembl chr 7:57,968,124...58,311,116
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| G
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Mst1
|
macrophage stimulating 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MST1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:117,646,485...117,652,016
Ensembl chr 8:117,647,438...117,652,015
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| G
|
Mt1-ps3
|
metallothionein 1, pseudogene 3
|
increases expression
|
ISO
|
Nickel results in increased expression of MT1E mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr17:79,695,812...79,696,200
Ensembl chr17:79,695,809...79,696,200
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|
| G
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Mt1a
|
metallothionein 1A
|
decreases response to substance multiple interactions increases response to substance increases expression
|
ISO
|
MT1 protein results in decreased susceptibility to Nickel MT1 affects the reaction [Nickel affects the expression of CALR3 mRNA]; MT1 affects the reaction [Nickel affects the expression of CANX mRNA]; MT1 affects the reaction [Nickel affects the expression of COPG2 mRNA]; MT1 affects the reaction [Nickel affects the expression of FBXL12 mRNA]; MT1 affects the reaction [Nickel affects the expression of GABARAPL2 mRNA]; MT1 affects the reaction [Nickel affects the expression of GRPEL1 mRNA]; MT1 affects the reaction [Nickel affects the expression of IPO4 mRNA]; MT1 affects the reaction [Nickel affects the expression of MARCHF2 mRNA]; MT1 affects the reaction [Nickel affects the expression of MRPS18A mRNA]; MT1 affects the reaction [Nickel affects the expression of PEX13 mRNA]; MT1 affects the reaction [Nickel affects the expression of PSMB7 mRNA]; MT1 affects the reaction [Nickel affects the expression of RAB32 mRNA]; MT1 affects the reaction [Nickel affects the expression of RNF11 mRNA]; MT1 affects the reaction [Nickel affects the expression of RNF114 mRNA]; MT1 affects the reaction [Nickel affects the expression of RNF13 mRNA]; MT1 affects the reaction [Nickel affects the expression of RNF19A mRNA]; MT1 affects the reaction [Nickel affects the expression of RPL15 mRNA]; MT1 affects the reaction [Nickel affects the expression of RPL19 mRNA]; MT1 affects the reaction [Nickel affects the expression of RPL29 mRNA]; MT1 affects the reaction [Nickel affects the expression of RPL35 mRNA]; MT1 affects the reaction [Nickel affects the expression of RPL36A mRNA]; MT1 affects the reaction [Nickel affects the expression of RPL4 mRNA]; MT1 affects the reaction [Nickel affects the expression of RPLP0 mRNA]; MT1 affects the reaction [Nickel affects the expression of RPS14 mRNA]; MT1 affects the reaction [Nickel affects the expression of RPS3 mRNA]; MT1 affects the reaction [Nickel affects the expression of RPS7 mRNA]; MT1 affects the reaction [Nickel affects the expression of SKP2 mRNA]; MT1 affects the reaction [Nickel affects the expression of SMURF2 mRNA]; MT1 affects the reaction [Nickel affects the expression of SNX1 mRNA]; MT1 affects the reaction [Nickel affects the expression of SNX12 mRNA]; MT1 affects the reaction [Nickel affects the expression of STX6 mRNA]; MT1 affects the reaction [Nickel affects the expression of UBB mRNA]; MT1 affects the reaction [Nickel affects the expression of VPS16 mRNA]; MT1 affects the reaction [Nickel affects the expression of VPS35 mRNA]; MT1 affects the reaction [Nickel affects the expression of YWHAB mRNA]; MT1 affects the reaction [Nickel affects the expression of ZBTB22 mRNA]; SFTPB protein affects the reaction [Nickel results in decreased expression of MT1 mRNA] MT1 gene mutant form results in increased susceptibility to Nickel Nickel results in increased expression of MT1 mRNA
|
CTD |
PMID:12540486 PMID:16166738 |
|
NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200 Ensembl chr X:79,695,809...79,696,200 Ensembl chr19:79,695,809...79,696,200
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|
| G
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Mt2
|
metallothionein 2
|
multiple interactions increases expression decreases response to substance increases response to substance
|
ISO
|
Acetylcysteine inhibits the reaction [Nickel results in increased expression of MT2A mRNA]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Nickel results in increased expression of MT2A mRNA] Nickel results in increased expression of MT2A mRNA; Nickel results in increased expression of MT2A protein MT2 protein results in decreased susceptibility to Nickel MT2 gene mutant form results in increased susceptibility to Nickel MT2 affects the reaction [Nickel affects the expression of CALR3 mRNA]; MT2 affects the reaction [Nickel affects the expression of CANX mRNA]; MT2 affects the reaction [Nickel affects the expression of COPG2 mRNA]; MT2 affects the reaction [Nickel affects the expression of FBXL12 mRNA]; MT2 affects the reaction [Nickel affects the expression of GABARAPL2 mRNA]; MT2 affects the reaction [Nickel affects the expression of GRPEL1 mRNA]; MT2 affects the reaction [Nickel affects the expression of IPO4 mRNA]; MT2 affects the reaction [Nickel affects the expression of MARCHF2 mRNA]; MT2 affects the reaction [Nickel affects the expression of MRPS18A mRNA]; MT2 affects the reaction [Nickel affects the expression of PEX13 mRNA]; MT2 affects the reaction [Nickel affects the expression of PSMB7 mRNA]; MT2 affects the reaction [Nickel affects the expression of RAB32 mRNA]; MT2 affects the reaction [Nickel affects the expression of RNF11 mRNA]; MT2 affects the reaction [Nickel affects the expression of RNF114 mRNA]; MT2 affects the reaction [Nickel affects the expression of RNF13 mRNA]; MT2 affects the reaction [Nickel affects the expression of RNF19A mRNA]; MT2 affects the reaction [Nickel affects the expression of RPL15 mRNA]; MT2 affects the reaction [Nickel affects the expression of RPL19 mRNA]; MT2 affects the reaction [Nickel affects the expression of RPL29 mRNA]; MT2 affects the reaction [Nickel affects the expression of RPL35 mRNA]; MT2 affects the reaction [Nickel affects the expression of RPL36A mRNA]; MT2 affects the reaction [Nickel affects the expression of RPL4 mRNA]; MT2 affects the reaction [Nickel affects the expression of RPLP0 mRNA]; MT2 affects the reaction [Nickel affects the expression of RPS14 mRNA]; MT2 affects the reaction [Nickel affects the expression of RPS3 mRNA]; MT2 affects the reaction [Nickel affects the expression of RPS7 mRNA]; MT2 affects the reaction [Nickel affects the expression of SKP2 mRNA]; MT2 affects the reaction [Nickel affects the expression of SMURF2 mRNA]; MT2 affects the reaction [Nickel affects the expression of SNX1 mRNA]; MT2 affects the reaction [Nickel affects the expression of SNX12 mRNA]; MT2 affects the reaction [Nickel affects the expression of STX6 mRNA]; MT2 affects the reaction [Nickel affects the expression of UBB mRNA]; MT2 affects the reaction [Nickel affects the expression of VPS16 mRNA]; MT2 affects the reaction [Nickel affects the expression of VPS35 mRNA]; MT2 affects the reaction [Nickel affects the expression of YWHAB mRNA]; MT2 affects the reaction [Nickel affects the expression of ZBTB22 mRNA]; SFTPB protein affects the reaction [Nickel results in decreased expression of MT2 mRNA]
|
CTD |
PMID:14971665 PMID:16166738 PMID:19097988 PMID:24768652 PMID:25583101 PMID:26378417 More...
|
|
NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,837,927...10,838,709
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|
| G
|
Mt2-ps1
|
metallothionein 2, pseudogene 1
|
increases expression
|
ISO
|
Nickel results in increased expression of MT1HL1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr20:3,163,749...3,164,121
|
|
| G
|
Mtarc1
|
mitochondrial amidoxime reducing component 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MTARC1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:98,854,235...98,894,208
Ensembl chr13:98,871,289...98,894,252
|
|
| G
|
Mtarc2
|
mitochondrial amidoxime reducing component 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MTARC2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:98,894,347...98,928,754
Ensembl chr13:98,897,108...98,928,781
|
|
| G
|
Mterf2
|
mitochondrial transcription termination factor 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MTERF2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:20,485,901...20,495,979
Ensembl chr 7:20,485,461...20,548,043
|
|
| G
|
Mtf1
|
metal-regulatory transcription factor 1
|
multiple interactions
|
ISO
|
Nickel affects the localization of and results in increased activity of MTF1 protein
|
CTD |
PMID:19097988 |
|
NCBI chr 5:142,347,024...142,391,810
Ensembl chr 5:142,347,054...142,391,810
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|
| G
|
Mtfp1
|
mitochondrial fission process 1
|
increases expression
|
ISO
|
Nickel results in increased expression of MTFP1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:83,192,013...83,195,853
Ensembl chr14:83,192,021...83,195,927
|
|
| G
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Mtfr2
|
mitochondrial fission regulator 2
|
increases expression
|
ISO
|
Nickel results in increased expression of MTFR2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:16,942,814...16,958,218
|
|
| G
|
Mthfd1l
|
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
|
increases expression
|
ISO
|
Nickel results in increased expression of MTHFD1L mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:42,849,424...43,038,313
Ensembl chr 1:42,849,374...43,038,309
|
|
| G
|
Mthfd2
|
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
|
increases expression
|
ISO
|
Nickel results in increased expression of MTHFD2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:117,368,833...117,380,350
Ensembl chr 4:117,368,835...117,380,350
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|
| G
|
Mthfr
|
methylenetetrahydrofolate reductase
|
increases expression
|
ISO
|
Nickel results in increased expression of MTHFR mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:163,748,346...163,768,141
Ensembl chr 5:163,748,321...163,768,105
|
|
| G
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Mtmr11
|
myotubularin related protein 11
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MTMR11 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:186,410,851...186,421,024
Ensembl chr 2:186,412,291...186,421,026
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|
| G
|
Mtnap1
|
mitochondrial nucleoid associated protein 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MTNAP1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr10:99,227,522...99,237,838
Ensembl chr10:99,226,698...99,237,836
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|
| G
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Mtor
|
mechanistic target of rapamycin kinase
|
multiple interactions
|
ISO
|
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Melatonin inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in decreased expression of MTOR mRNA]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Melatonin inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in decreased phosphorylation of MTOR protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [[nickel chloride results in increased abundance of Nickel] which results in decreased expression of MTOR mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [[nickel chloride results in increased abundance of Nickel] which results in decreased phosphorylation of MTOR protein]; [nickel chloride results in increased abundance of Nickel] which results in decreased expression of MTOR mRNA; [nickel chloride results in increased abundance of Nickel] which results in decreased phosphorylation of MTOR protein; Melatonin inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in decreased expression of MTOR mRNA]; Melatonin inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in decreased phosphorylation of MTOR protein] [cobalt ferrite binds to Nickel] which results in decreased phosphorylation of MTOR protein
|
CTD |
PMID:35568058 PMID:36073959 |
|
NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435
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|
| G
|
Mtrr
|
5-methyltetrahydrofolate-homocysteine methyltransferase reductase
|
increases expression
|
ISO
|
Nickel results in increased expression of MTRR mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:36,695,376...36,727,341
Ensembl chr 1:36,695,460...36,727,807
|
|
| G
|
Mttp
|
microsomal triglyceride transfer protein
|
multiple interactions affects expression
|
ISO
|
trichostatin A inhibits the reaction [Nickel affects the expression of MTTP mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 2:229,286,501...229,327,650
Ensembl chr 2:229,286,501...229,327,650
|
|
| G
|
Mturn
|
maturin, neural progenitor differentiation regulator homolog
|
increases expression decreases expression
|
ISO
|
Nickel results in increased expression of MTURN mRNA Nickel results in decreased expression of MTURN mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr 4:85,137,825...85,158,790
Ensembl chr 4:85,137,846...85,158,789
|
|
| G
|
Mtus1
|
microtubule associated scaffold protein 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MTUS1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr16:57,905,991...58,051,466
Ensembl chr16:57,906,128...58,051,474
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|
| G
|
Muc15
|
mucin 15, cell surface associated
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MUC15 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 3:117,749,161...117,761,466
Ensembl chr 3:117,749,324...117,762,101
|
|
| G
|
Muc20
|
mucin 20, cell surface associated
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MUC20 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr11:81,492,844...81,506,571
Ensembl chr11:81,492,891...81,506,571
|
|
| G
|
Muc5ac
|
mucin 5AC, oligomeric mucus/gel-forming
|
multiple interactions
|
ISO
|
[TBX21 gene mutant form results in increased susceptibility to Nickel analog] which results in increased expression of MUC5AC mRNA; CCL2 protein affects the reaction [[TBX21 gene mutant form results in increased susceptibility to Nickel analog] which results in increased expression of MUC5AC mRNA]
|
CTD |
PMID:24499286 |
|
NCBI chr 1:206,293,717...206,326,006
Ensembl chr 1:206,293,869...206,326,006
|
|
| G
|
Muc5b
|
mucin 5B, oligomeric mucus/gel-forming
|
multiple interactions
|
ISO
|
[TBX21 gene mutant form results in increased susceptibility to Nickel analog] which results in increased expression of MUC5B mRNA
|
CTD |
PMID:24499286 |
|
NCBI chr 1:206,346,400...206,378,367
Ensembl chr 1:206,346,400...206,378,367
|
|
| G
|
Mug2
|
murinoglobulin 2
|
affects binding
|
ISO
|
PZP protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr 4:156,836,140...156,908,972
|
|
| G
|
Mvb12a
|
multivesicular body subunit 12A
|
increases expression
|
ISO
|
Nickel results in increased expression of MVB12A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr16:18,286,231...18,291,096
Ensembl chr16:18,286,231...18,292,583
|
|
| G
|
Mvk
|
mevalonate kinase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MVK mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr12:47,802,002...47,819,503
Ensembl chr12:47,802,002...47,819,503
|
|
| G
|
Mvp
|
major vault protein
|
increases expression
|
ISO
|
Nickel results in increased expression of MVP mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:191,025,259...191,052,866
Ensembl chr 1:191,025,268...191,052,873
|
|
| G
|
Mx1
|
MX dynamin like GTPase 1
|
multiple interactions increases expression affects expression
|
ISO
|
trichostatin A inhibits the reaction [Nickel affects the expression of MX1 mRNA] Nickel results in increased expression of MX1 mRNA
|
CTD |
PMID:14575637 PMID:24768652 PMID:25583101 |
|
NCBI chr11:50,269,056...50,294,699
Ensembl chr11:50,269,057...50,292,904
|
|
| G
|
Mx2
|
MX dynamin like GTPase 2
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of MX2 mRNA Nickel results in increased expression of MX2 mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr11:50,375,101...50,399,373
Ensembl chr11:50,375,191...50,402,478
|
|
| G
|
Mxra7
|
matrix remodeling associated 7
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MXRA7 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:102,501,848...102,530,231
Ensembl chr10:102,489,604...102,530,231
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|
| G
|
Myadm
|
myeloid-associated differentiation marker
|
increases expression
|
ISO
|
Nickel results in increased expression of MYADM mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 1:74,779,616...74,796,752
Ensembl chr 1:74,775,698...74,789,710
|
|
| G
|
Mybl1
|
MYB proto-oncogene like 1
|
increases expression
|
ISO
|
Nickel results in increased expression of MYBL1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:14,365,768...14,401,012
Ensembl chr 5:14,365,768...14,399,588
|
|
| G
|
Mybpc1
|
myosin binding protein C1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MYBPC1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:24,817,770...24,903,681
Ensembl chr 7:24,817,561...24,903,544
|
|
| G
|
Myc
|
MYC proto-oncogene, bHLH transcription factor
|
increases expression
|
ISO
|
Nickel results in increased expression of MYC mRNA
|
CTD |
PMID:12540486 PMID:24768652 PMID:25583101 |
|
NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
|
|
| G
|
Myd88
|
MYD88, innate immune signal transduction adaptor
|
increases expression
|
ISO
|
Nickel results in increased expression of MYD88 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:127,952,161...127,956,230
|
|
| G
|
Myef2
|
myelin expression factor 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MYEF2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:132,791,694...132,827,572
Ensembl chr 3:132,791,694...132,827,523
|
|
| G
|
Myg1
|
MYG1 exonuclease
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MYG1 mRNA
|
CTD |
PMID:18922574 |
|
NCBI chr 7:135,335,364...135,342,567
Ensembl chr 7:135,335,334...135,346,740
|
|
| G
|
Myh10
|
myosin heavy chain 10
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MYH10 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:53,891,955...54,024,032
Ensembl chr10:53,893,166...54,024,036
|
|
| G
|
Myh11
|
myosin heavy chain 11
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MYH11 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:1,250,554...1,345,681
Ensembl chr10:1,263,194...1,345,678
|
|
| G
|
Myh3
|
myosin heavy chain 3
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of MYH3 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of MYH3 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr10:52,269,185...52,293,000
Ensembl chr10:52,269,185...52,293,000
|
|
| G
|
Myl12a
|
myosin light chain 12A
|
increases expression
|
ISO
|
Nickel results in increased expression of MYL12A mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 9:118,338,592...118,346,277
Ensembl chr 9:118,338,604...118,342,634
|
|
| G
|
Myl9
|
myosin light chain 9
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MYL9 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:165,742,020...165,748,409
Ensembl chr 3:165,742,046...165,748,410
|
|
| G
|
Mylk
|
myosin light chain kinase
|
increases expression decreases expression
|
ISO
|
Nickel results in increased expression of MYLK mRNA Nickel results in decreased expression of MYLK mRNA
|
CTD |
PMID:18922574 PMID:24768652 PMID:25583101 |
|
NCBI chr11:79,288,243...79,535,450
Ensembl chr11:79,288,243...79,535,659
|
|
| G
|
Myo15b
|
myosin XVB
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MYO15B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:101,587,672...101,625,092
Ensembl chr10:101,587,672...101,625,092
|
|
| G
|
Myo19
|
myosin XIX
|
increases expression
|
ISO
|
Nickel results in increased expression of MYO19 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:70,250,500...70,279,867
Ensembl chr10:70,250,022...70,279,858
|
|
| G
|
Myo1b
|
myosin Ib
|
increases expression
|
ISO
|
Nickel results in increased expression of MYO1B mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:57,182,059...57,344,335
Ensembl chr 9:57,181,987...57,344,328
|
|
| G
|
Myo1f
|
myosin IF
|
increases expression
|
ISO
|
Nickel results in increased expression of MYO1F mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:15,065,530...15,116,087
Ensembl chr 7:15,065,530...15,116,087
|
|
| G
|
Myo1g
|
myosin IG
|
increases expression
|
ISO
|
Nickel results in increased expression of MYO1G mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr14:85,600,619...85,615,760
Ensembl chr14:85,600,619...85,615,760
|
|
| G
|
Myo3a
|
myosin IIIA
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MYO3A mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr17:89,451,567...89,667,654
Ensembl chr17:89,451,567...89,667,654
|
|
| G
|
Myo5a
|
myosin VA
|
increases expression
|
ISO
|
Nickel results in increased expression of MYO5A mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:84,692,524...84,860,564
Ensembl chr 8:84,692,910...84,856,265
|
|
| G
|
Myo5c
|
myosin VC
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MYO5C mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:84,870,031...84,946,996
Ensembl chr 8:84,870,043...84,946,996
|
|
| G
|
Myoc
|
myocilin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MYOC mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:77,509,963...77,520,361
Ensembl chr13:77,509,963...77,520,361
|
|
| G
|
Myocd
|
myocardin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MYOCD mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:50,332,356...50,426,819
Ensembl chr10:50,332,356...50,426,819
|
|
| G
|
Myof
|
myoferlin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MYOF mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 1:245,086,109...245,234,768
Ensembl chr 1:245,086,109...245,234,768
|
|
| G
|
Myom1
|
myomesin 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MYOM1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 9:118,362,547...118,485,954
Ensembl chr 9:118,362,621...118,485,952
|
|
| G
|
Myot
|
myotilin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MYOT mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr18:36,956,119...36,975,728
Ensembl chr18:36,956,191...36,976,265
|
|
| G
|
Myrip
|
myosin VIIA and Rab interacting protein
|
decreases expression
|
ISO
|
Nickel results in decreased expression of MYRIP mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:128,895,371...129,062,420
Ensembl chr 8:128,895,371...129,062,420
|
|
| G
|
Myt1l
|
myelin transcription factor 1-like
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of MYT1L mRNA trichostatin A inhibits the reaction [Nickel affects the expression of MYT1L mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 6:51,892,858...52,291,830
Ensembl chr 6:52,155,754...52,291,828
|
|
| G
|
N4bp1
|
Nedd4 binding protein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of N4BP1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr19:36,396,082...36,446,835
Ensembl chr19:36,396,324...36,446,835
|
|
| G
|
N4bp2l1
|
NEDD4 binding protein 2-like 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of N4BP2L1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr12:4,938,199...4,965,003
Ensembl chr12:4,927,142...4,963,045
|
|
| G
|
N6amt1
|
N-6 adenine-specific DNA methyltransferase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of HEMK2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:40,071,017...40,083,463
Ensembl chr11:40,070,993...40,083,680
|
|
| G
|
Naa15
|
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
|
increases expression
|
ISO
|
Nickel results in increased expression of NAA15 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:137,608,883...137,671,618
Ensembl chr 2:137,608,797...137,671,619
|
|
| G
|
Naa20
|
N(alpha)-acetyltransferase 20, NatB catalytic subunit
|
increases expression
|
ISO
|
Nickel results in increased expression of NAA20 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:153,775,351...153,790,129
Ensembl chr 3:153,775,338...153,790,916
|
|
| G
|
Naa25
|
N(alpha)-acetyltransferase 25, NatB auxiliary subunit
|
increases expression
|
ISO
|
Nickel results in increased expression of NAA25 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr12:40,758,909...40,811,192
Ensembl chr12:40,758,728...40,811,291
|
|
| G
|
Naalad2
|
N-acetylated alpha-linked acidic dipeptidase 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NAALAD2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:23,682,499...23,756,066
Ensembl chr 8:23,683,395...23,756,060
|
|
| G
|
Nabp1
|
nucleic acid binding protein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of NABP1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:57,570,326...57,625,926
Ensembl chr 9:57,618,505...57,626,052
|
|
| G
|
Naca
|
nascent polypeptide associated complex subunit alpha
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of NACA mRNA trichostatin A inhibits the reaction [Nickel affects the expression of NACA mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 7:1,053,474...1,066,606
Ensembl chr 7:1,054,338...1,066,605
|
|
| G
|
Nadk
|
NAD kinase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NADK mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 5:171,427,973...171,458,586
Ensembl chr 5:171,428,000...171,458,579
|
|
| G
|
Naga
|
alpha-N-acetylgalactosaminidase
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of NAGA mRNA Nickel results in increased expression of NAGA mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr 7:115,726,438...115,735,494
Ensembl chr 7:115,726,624...115,736,828
|
|
| G
|
Nagk
|
N-acetylglucosamine kinase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NAGK mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 4:117,838,761...117,846,304
Ensembl chr 4:117,838,826...117,847,836
|
|
| G
|
Naip6
|
NLR family, apoptosis inhibitory protein 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NAIP mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 2:33,241,520...33,293,184
Ensembl chr 2:33,241,521...33,276,859
|
|
| G
|
Nalcn
|
sodium leak channel, non-selective
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NALCN mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr15:106,805,209...107,148,837
Ensembl chr15:106,805,209...107,147,858
|
|
| G
|
Nampt
|
nicotinamide phosphoribosyltransferase
|
increases expression
|
ISO
|
Nickel results in increased expression of NAMPT mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:55,152,756...55,189,547
Ensembl chr 6:55,151,926...55,189,544
|
|
| G
|
Nap1l3
|
nucleosome assembly protein 1-like 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NAP1L3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr X:92,607,628...92,610,426
Ensembl chr X:92,604,626...92,610,687
|
|
| G
|
Napepld
|
N-acyl phosphatidylethanolamine phospholipase D
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NAPEPLD mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 4:14,251,591...14,291,010
Ensembl chr 4:14,252,692...14,291,014
|
|
| G
|
Napg
|
NSF attachment protein gamma
|
increases expression
|
ISO
|
Nickel results in increased expression of NAPG mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr18:58,710,702...58,729,450
Ensembl chr18:58,708,655...58,729,450
|
|
| G
|
Nars1
|
asparaginyl-tRNA synthetase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NARS1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr18:60,259,506...60,275,782
Ensembl chr18:60,259,516...60,275,782
|
|
| G
|
Nav1
|
neuron navigator 1
|
increases expression
|
ISO
|
Nickel results in increased expression of NAV1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:49,418,755...49,671,117
Ensembl chr13:49,418,755...49,671,004
|
|
| G
|
Nav2
|
neuron navigator 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NAV2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:107,799,968...108,458,546
Ensembl chr 1:107,805,096...108,458,546
|
|
| G
|
Nbea
|
neurobeachin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NBEA mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:141,930,147...142,489,172
Ensembl chr 2:141,930,147...142,489,172
|
|
| G
|
Nbr1
|
NBR1, autophagy cargo receptor
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NBR1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr10:86,978,024...87,006,664
Ensembl chr10:86,977,885...87,007,012
|
|
| G
|
Ncald
|
neurocalcin delta
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NCALD mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:70,417,683...70,849,763
Ensembl chr 7:70,419,433...70,849,482
|
|
| G
|
Ncam1
|
neural cell adhesion molecule 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NCAM1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 8:58,762,088...59,062,131
Ensembl chr 8:58,762,116...59,061,971
|
|
| G
|
Ncapd2
|
non-SMC condensin I complex, subunit D2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NCAPD2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 4:159,655,051...159,677,938
Ensembl chr 4:159,655,051...159,677,938
|
|
| G
|
Ncapg
|
non-SMC condensin I complex, subunit G
|
increases expression
|
ISO
|
Nickel results in increased expression of NCAPG mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr14:69,616,473...69,645,445
Ensembl chr14:69,616,473...69,645,445
|
|
| G
|
Ncaph2
|
non-SMC condensin II complex, subunit H2
|
increases expression
|
ISO
|
Nickel results in increased expression of NCAPH2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:122,302,550...122,319,570
Ensembl chr 7:122,300,252...122,319,569
|
|
| G
|
Ncbp2
|
nuclear cap binding protein subunit 2
|
increases expression
|
ISO
|
Nickel results in increased expression of NCBP2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr11:82,326,002...82,334,839
Ensembl chr11:82,322,716...82,335,116
|
|
| G
|
Nceh1
|
neutral cholesterol ester hydrolase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of NCEH1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:112,003,677...112,064,274
Ensembl chr 2:112,003,502...112,064,272
|
|
| G
|
Ncf2
|
neutrophil cytosolic factor 2
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of NCF2 mRNA Nickel results in increased expression of NCF2 mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr13:67,505,492...67,536,015
Ensembl chr13:67,505,375...67,536,149
|
|
| G
|
Ncf4
|
neutrophil cytosolic factor 4
|
increases expression
|
ISO
|
Nickel results in increased expression of NCF4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:111,705,926...111,723,893
Ensembl chr 7:111,706,520...111,723,898
|
|
| G
|
Nckap1l
|
NCK associated protein 1 like
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of NCKAP1L mRNA Nickel results in increased expression of NCKAP1L mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr 7:136,455,900...136,501,384
Ensembl chr 7:136,455,897...136,501,384
|
|
| G
|
Nckap5
|
NCK-associated protein 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NCKAP5 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:39,922,576...40,835,849
Ensembl chr13:39,922,737...40,835,521
|
|
| G
|
Ncln
|
nicalin
|
increases expression
|
ISO
|
Nickel results in increased expression of NCLN mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:8,862,324...8,872,699
Ensembl chr 7:8,862,751...8,872,698
|
|
| G
|
Ncoa3
|
nuclear receptor coactivator 3
|
increases expression
|
ISO
|
Nickel results in increased expression of NCOA3 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 3:175,157,824...175,237,831
Ensembl chr 3:175,157,821...175,240,631
|
|
| G
|
Ncoa4
|
nuclear receptor coactivator 4
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of NCOA4 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of NCOA4 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr16:7,395,502...7,415,846
Ensembl chr16:7,401,802...7,415,840
|
|
| G
|
Ncoa7
|
nuclear receptor coactivator 7
|
increases expression
|
ISO
|
Nickel results in increased expression of NCOA7 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:28,674,614...28,835,891
Ensembl chr 1:28,675,426...28,835,886
|
|
| G
|
Ncr1
|
natural cytotoxicity triggering receptor 1
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of NCR1 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of NCR1 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 1:78,657,409...78,665,255
Ensembl chr 1:78,659,262...78,703,273
|
|
| G
|
Ncr3lg1
|
natural killer cell cytotoxicity receptor 3 ligand 1
|
increases expression
|
ISO
|
Nickel results in increased expression of NCR3LG1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 1:105,701,953...105,718,251
Ensembl chr 1:105,710,883...105,716,732
|
|
| G
|
Ndc1
|
NDC1 transmembrane nucleoporin
|
increases expression
|
ISO
|
Nickel results in increased expression of NDC1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:127,384,172...127,431,093
Ensembl chr 5:127,384,665...127,431,090
|
|
| G
|
Ndc80
|
NDC80 kinetochore complex component
|
increases expression
|
ISO
|
Nickel results in increased expression of NDC80 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 9:118,853,806...118,887,582
Ensembl chr 9:118,853,806...118,887,568
|
|
| G
|
Ndnf
|
neuron-derived neurotrophic factor
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NDNF mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:96,274,147...96,311,624
Ensembl chr 4:96,274,147...96,311,624
|
|
| G
|
Ndp
|
norrin cystine knot growth factor NDP
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NDP mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr X:8,379,569...8,404,019
Ensembl chr X:8,379,569...8,406,802
|
|
| G
|
Ndrg1
|
N-myc downstream regulated 1
|
increases expression multiple interactions
|
ISO
|
Nickel results in increased expression of NDRG1 mRNA Nickel results in increased expression of NDRG1 mRNA; Nickel results in increased expression of NDRG1 protein HIF1A protein promotes the reaction [Nickel results in increased expression of NDRG1 mRNA]; HIF1A protein promotes the reaction [Nickel results in increased expression of NDRG1 protein]
|
CTD |
PMID:15341671 PMID:16386771 PMID:18922574 |
|
NCBI chr 7:100,573,526...100,614,902
Ensembl chr 7:100,573,523...100,614,913
|
|
| G
|
Ndrg2
|
NDRG family member 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NDRG2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr15:27,074,481...27,087,376
Ensembl chr15:27,074,481...27,083,125
|
|
| G
|
Ndrg4
|
NDRG family member 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NDRG4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr19:9,357,470...9,393,465
Ensembl chr19:9,357,470...9,392,972
|
|
| G
|
Ndufa8
|
NADH:ubiquinone oxidoreductase subunit A8
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NDUFA8 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 3:39,783,479...39,799,507
Ensembl chr 3:39,783,479...39,799,507
|
|
| G
|
Ndufaf1
|
NADH:ubiquinone oxidoreductase complex assembly factor 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NDUFAF1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 3:127,089,893...127,104,357
Ensembl chr 3:127,093,659...127,104,020
|
|
| G
|
Ndufb6
|
NADH:ubiquinone oxidoreductase subunit B6
|
multiple interactions affects expression
|
ISO
|
trichostatin A inhibits the reaction [Nickel affects the expression of NDUFB6 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 5:60,196,585...60,206,152
Ensembl chr 5:60,196,585...60,206,055
|
|
| G
|
Ndufc1
|
NADH:ubiquinone oxidoreductase subunit C1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NDUFC1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:137,597,944...137,601,819
Ensembl chr 2:137,600,156...137,601,735
|
|
| G
|
Ndufc2
|
NADH:ubiquinone oxidoreductase subunit C2
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of NDUFC2 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of NDUFC2 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 1:161,122,370...161,129,413
Ensembl chr 1:161,123,150...161,129,419
|
|
| G
|
Nebl
|
nebulette
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NEBL mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr17:85,022,953...85,374,848
Ensembl chr17:85,022,963...85,374,172
|
|
| G
|
Nectin2
|
nectin cell adhesion molecule 2
|
increases expression
|
ISO
|
Nickel results in increased expression of NECTIN2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 1:88,500,086...88,535,474
Ensembl chr 1:88,500,087...88,535,305
|
|
| G
|
Nedd4l
|
NEDD4 like E3 ubiquitin protein ligase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NEDD4L mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr18:60,663,918...60,996,824
Ensembl chr18:60,663,970...60,996,824
|
|
| G
|
Nefm
|
neurofilament medium chain
|
affects expression
|
EXP
|
Nickel affects the expression of NEFM mRNA
|
CTD |
PMID:18812211 |
|
NCBI chr15:46,535,857...46,541,161
Ensembl chr15:46,535,517...46,541,163
|
|
| G
|
Negr1
|
neuronal growth regulator 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NEGR1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:248,283,164...249,015,538
Ensembl chr 2:248,283,353...249,018,410
|
|
| G
|
Neil1
|
nei-like DNA glycosylase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NEIL1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:66,446,106...66,452,844
Ensembl chr 8:66,445,953...66,452,378
|
|
| G
|
Nek2
|
NIMA-related kinase 2
|
increases expression
|
ISO
|
Nickel results in increased expression of NEK2 mRNA
|
CTD |
PMID:19031421 |
|
NCBI chr13:105,936,809...105,950,054
Ensembl chr13:105,936,788...105,950,056
|
|
| G
|
Nek4
|
NIMA-related kinase 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NEK4 mRNA
|
CTD |
PMID:19031421 |
|
NCBI chr16:6,151,292...6,200,280
Ensembl chr16:6,151,368...6,198,450
|
|
| G
|
Nek6
|
NIMA-related kinase 6
|
increases expression
|
ISO
|
Nickel results in increased expression of NEK6 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:42,693,994...42,766,026
Ensembl chr 3:42,693,971...42,767,773
|
|
| G
|
Nek7
|
NIMA-related kinase 7
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NEK7 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr13:52,573,730...52,700,869
Ensembl chr13:52,573,730...52,700,823
|
|
| G
|
Nell2
|
neural EGFL like 2
|
increases expression
|
ISO
|
Nickel results in increased expression of NELL2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:128,222,333...128,542,127
Ensembl chr 7:128,078,103...128,651,917
|
|
| G
|
Neo1
|
neogenin 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NEO1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:68,169,711...68,322,158
Ensembl chr 8:68,169,716...68,322,152
|
|
| G
|
Neto2
|
neuropilin and tolloid like 2
|
increases expression
|
ISO
|
Nickel results in increased expression of NETO2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr19:37,517,518...37,588,961
Ensembl chr19:37,517,587...37,591,413
|
|
| G
|
Neurl2
|
neuralized E3 ubiquitin protein ligase 2
|
increases expression
|
ISO
|
Nickel results in increased expression of NEURL2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:173,985,996...173,988,717
Ensembl chr 3:173,986,857...173,989,043
|
|
| G
|
Nexmif
|
neurite extension and migration factor
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NEXMIF mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:73,153,786...73,284,943
Ensembl chr X:73,153,786...73,178,639
|
|
| G
|
Nexn
|
nexilin (F actin binding protein)
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NEXN mRNA
|
CTD |
PMID:18922574 |
|
NCBI chr 2:243,846,736...243,878,268
Ensembl chr 2:243,846,433...243,887,114
|
|
| G
|
Nf1
|
neurofibromin 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NF1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:64,803,986...65,037,086
Ensembl chr10:64,804,266...65,034,946
|
|
| G
|
Nf2
|
NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor
|
increases expression
|
ISO
|
Nickel results in increased expression of NF2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr14:83,850,894...83,934,263
Ensembl chr14:83,850,894...83,934,151
|
|
| G
|
Nfatc2ip
|
nuclear factor of activated T-cells 2 interacting protein
|
increases expression
|
ISO
|
Nickel results in increased expression of NFATC2IP mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 1:190,385,416...190,403,309
Ensembl chr 1:190,387,437...190,402,413
|
|
| G
|
Nfatc4
|
nuclear factor of activated T-cells 4
|
multiple interactions decreases expression
|
ISO
|
NFATC4 mRNA affects the reaction [Nickel results in increased expression of PTGS2] Nickel results in decreased expression of NFATC4 mRNA
|
CTD |
PMID:21486220 PMID:24768652 PMID:25583101 |
|
NCBI chr15:33,256,912...33,284,522
Ensembl chr15:33,274,153...33,285,582
|
|
| G
|
Nfe2l3
|
NFE2 like bZIP transcription factor 3
|
increases expression
|
ISO
|
Nickel results in increased expression of NFE2L3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:81,837,404...81,865,258
Ensembl chr 4:81,837,404...81,865,532
|
|
| G
|
Nfia
|
nuclear factor I/A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NFIA mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:117,359,006...117,897,391
Ensembl chr 5:117,359,077...117,891,395
|
|
| G
|
Nfib
|
nuclear factor I/B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NFIB mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:101,805,168...102,020,618
Ensembl chr 5:101,805,168...102,019,945
|
|
| G
|
Nfix
|
nuclear factor I X
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NFIX mRNA
|
CTD |
PMID:12540486 PMID:24768652 PMID:25583101 |
|
NCBI chr19:40,259,873...40,356,966
Ensembl chr19:40,260,084...40,353,092
|
|
| G
|
Nfkb1
|
nuclear factor kappa B subunit 1
|
increases expression multiple interactions
|
ISO
|
Nickel results in increased expression of NFKB1 mRNA [nickel chloride results in increased abundance of Nickel] which results in increased expression of NFKB1 protein
|
CTD |
PMID:25583101 PMID:30724446 |
|
NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088
|
|
| G
|
Nfkb2
|
nuclear factor kappa B subunit 2
|
increases expression
|
ISO
|
Nickel results in increased expression of NFKB2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:255,106,010...255,114,649
Ensembl chr 1:255,107,374...255,114,637
|
|
| G
|
Nfkbia
|
NFKB inhibitor alpha
|
multiple interactions increases expression
|
EXP ISO
|
[Nickel co-treated with Cobalt co-treated with Tungsten] results in increased expression of NFKBIA mRNA Nickel results in increased expression of NFKBIA mRNA
|
CTD |
PMID:12540486 PMID:22198552 |
|
NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
|
|
| G
|
Nfkbib
|
NFKB inhibitor beta
|
increases expression
|
ISO
|
Nickel results in increased expression of NFKBIB mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:93,173,817...93,181,387
Ensembl chr 1:93,173,820...93,326,366
|
|
| G
|
Nfkbid
|
NFKB inhibitor delta
|
increases expression
|
ISO
|
Nickel results in increased expression of NFKBID mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr 1:94,808,459...94,824,726
Ensembl chr 1:94,808,453...94,817,861
|
|
| G
|
Nfkbie
|
NFKB inhibitor epsilon
|
increases expression
|
ISO
|
Nickel results in increased expression of NFKBIE mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:22,941,037...22,947,872
Ensembl chr 9:22,941,040...22,947,872
|
|
| G
|
Ngf
|
nerve growth factor
|
affects expression multiple interactions
|
EXP ISO
|
Nickel affects the expression of NGF mRNA [Nickel co-treated with NGF protein] results in increased expression of SLC1A5 mRNA
|
CTD |
PMID:19130878 PMID:20600679 |
|
NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:192,589,582...192,643,834
|
|
| G
|
Nherf1
|
NHERF family PDZ scaffold protein 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NHERF1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr10:100,902,165...100,919,265
Ensembl chr10:100,901,227...100,919,579
|
|
| G
|
Nherf2
|
NHERF family PDZ scaffold protein 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NHERF2 mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr10:14,167,005...14,177,519
Ensembl chr10:14,167,005...14,177,593
|
|
| G
|
Nhlh2
|
nescient helix loop helix 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NHLH2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 2:192,132,848...192,138,186
Ensembl chr 2:192,132,686...192,138,186
|
|
| G
|
Nhsl2
|
NHS-like 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NHSL2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr X:71,009,940...71,249,427
Ensembl chr X:71,009,949...71,241,289
|
|
| G
|
Niban3
|
niban apoptosis regulator 3
|
increases expression
|
ISO
|
Nickel results in increased expression of NIBAN3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr16:18,341,108...18,352,571
Ensembl chr16:18,341,141...18,352,575
|
|
| G
|
Ninj1
|
ninjurin 1
|
increases expression
|
ISO
|
Nickel results in increased expression of NINJ1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr17:15,659,208...15,668,115
Ensembl chr17:15,659,200...15,668,063
|
|
| G
|
Ninl
|
ninein-like
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NINL mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:160,208,757...160,275,077
Ensembl chr 3:160,196,883...160,275,108
|
|
| G
|
Nip7
|
nucleolar pre-rRNA processing protein NIP7
|
increases expression
|
ISO
|
Nickel results in increased expression of NIP7 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr19:51,872,306...51,874,448
Ensembl chr19:51,872,364...51,876,120
|
|
| G
|
Nipal4
|
NIPA-like domain containing 4
|
increases expression
|
ISO
|
Nickel results in increased expression of NIPAL4 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr10:31,085,267...31,101,979
Ensembl chr10:31,085,267...31,101,979
|
|
| G
|
Nkain3
|
Sodium/potassium transporting ATPase interacting 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NKAIN3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:38,410,576...39,106,910
Ensembl chr 5:38,386,841...39,106,385
|
|
| G
|
Nkg7
|
natural killer cell granule protein 7
|
increases expression
|
ISO
|
Nickel results in increased expression of NKG7 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:102,981,497...102,982,564
Ensembl chr 1:102,981,450...102,982,562
|
|
| G
|
Nln
|
neurolysin
|
increases expression decreases expression
|
ISO
|
Nickel results in increased expression of NLN mRNA Nickel results in decreased expression of NLN mRNA
|
CTD |
PMID:23195993 PMID:24768652 |
|
NCBI chr 2:36,867,436...36,966,749
Ensembl chr 2:36,853,551...36,966,680
|
|
| G
|
Nlrc4
|
NLR family, CARD domain containing 4
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of NLRC4 mRNA Nickel results in increased expression of NLRC4 mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr 6:26,743,658...26,771,783
Ensembl chr 6:26,743,698...26,770,563
|
|
| G
|
Nlrc5
|
NLR family, CARD domain containing 5
|
increases expression
|
ISO
|
Nickel results in increased expression of NLRC5 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr19:10,483,601...10,587,223
Ensembl chr19:10,483,755...10,555,786
|
|
| G
|
Nlrp12
|
NLR family, pyrin domain containing 12
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NLRP12 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 1:74,848,020...74,885,945
Ensembl chr 1:74,848,063...74,876,341
|
|
| G
|
Nlrp3
|
NLR family, pyrin domain containing 3
|
increases expression multiple interactions
|
ISO
|
Nickel results in increased expression of NLRP3 mRNA [Nickel co-treated with Melatonin] results in decreased expression of NLRP3 protein; [SELENOM protein affects the susceptibility to Nickel] which affects the expression of NLRP3 mRNA; [SELENOM protein affects the susceptibility to Nickel] which affects the expression of NLRP3 protein; Melatonin affects the reaction [[SELENOM protein affects the susceptibility to Nickel] which affects the expression of NLRP3 mRNA]; Melatonin affects the reaction [[SELENOM protein affects the susceptibility to Nickel] which affects the expression of NLRP3 protein]; Nickel inhibits the reaction [Melatonin results in decreased expression of NLRP3 mRNA] [nickel chloride results in increased abundance of Nickel] which results in increased expression of NLRP3 protein; Resveratrol inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of NLRP3 protein]
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 PMID:31943712 PMID:36504304 |
|
NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394
|
|
| G
|
Nmb
|
neuromedin B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NMB mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:144,278,678...144,290,523
Ensembl chr 1:144,278,453...144,281,422
|
|
| G
|
Nme1
|
NME/NM23 nucleoside diphosphate kinase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of NME1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:79,403,939...79,426,620
Ensembl chr10:79,403,940...79,413,310
|
|
| G
|
Nme3
|
NME/NM23 nucleoside diphosphate kinase 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NME3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:14,421,922...14,422,878
Ensembl chr10:14,421,702...14,422,907
|
|
| G
|
Nme5
|
NME/NM23 family member 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NME5 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr18:26,437,705...26,454,828
Ensembl chr18:26,437,781...26,454,828
|
|
| G
|
Nmi
|
N-myc (and STAT) interactor
|
increases expression
|
ISO
|
Nickel results in increased expression of NMI mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:56,824,778...56,848,891
Ensembl chr 3:56,811,314...56,848,717
|
|
| G
|
Nmnat3
|
nicotinamide nucleotide adenylyltransferase 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NMNAT3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:107,771,124...107,888,528
Ensembl chr 8:107,771,509...107,900,016
|
|
| G
|
Nmt1
|
N-myristoyltransferase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of NMT1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:88,488,918...88,525,496
Ensembl chr10:88,488,990...88,522,729
|
|
| G
|
Nmt2
|
N-myristoyltransferase 2
|
multiple interactions
|
EXP
|
[Tungsten co-treated with Nickel co-treated with Cobalt] results in increased expression of NMT2 mRNA; [Tungsten co-treated with Nickel co-treated with Iron] results in increased expression of NMT2 mRNA
|
CTD |
PMID:24619124 |
|
NCBI chr17:79,826,999...79,874,088
Ensembl chr17:79,826,999...79,870,259
|
|
| G
|
Nnmt
|
nicotinamide N-methyltransferase
|
increases expression
|
ISO
|
Nickel results in increased expression of NNMT mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:57,820,156...57,851,301
Ensembl chr 8:57,825,464...57,843,174
|
|
| G
|
Noct
|
nocturnin
|
increases expression
|
ISO
|
Nickel results in increased expression of NOCT mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr 2:137,422,074...137,442,282
Ensembl chr 2:137,422,074...137,442,282
|
|
| G
|
Nod1
|
nucleotide-binding oligomerization domain containing 1
|
increases expression
|
ISO
|
Nickel results in increased expression of NOD1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:85,391,142...85,442,281
Ensembl chr 4:85,391,151...85,441,674
|
|
| G
|
Nod2
|
nucleotide-binding oligomerization domain containing 2
|
increases expression
|
ISO
|
Nickel results in increased expression of NOD2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr19:34,555,832...34,596,281
Ensembl chr19:34,555,832...34,722,846
|
|
| G
|
Nog
|
noggin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NOG mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:74,625,874...74,627,501
Ensembl chr10:74,625,875...74,628,103
|
|
| G
|
Nol3
|
nucleolar protein 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NOL3 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr19:50,066,493...50,068,175
Ensembl chr19:50,063,986...50,068,722
|
|
| G
|
Nol6
|
nucleolar protein 6
|
increases expression
|
ISO
|
Nickel results in increased expression of NOL6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:61,055,863...61,083,249
Ensembl chr 5:61,055,863...61,083,264
|
|
| G
|
Nolc1
|
nucleolar and coiled-body phosphoprotein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of NOLC1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:254,870,195...254,881,070
Ensembl chr 1:254,870,319...254,881,069
|
|
| G
|
Nop16
|
NOP16 nucleolar protein
|
increases expression
|
ISO
|
Nickel results in increased expression of NOP16 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr17:10,028,058...10,032,975
Ensembl chr17:10,028,034...10,033,038
|
|
| G
|
Nop2
|
NOP2 nucleolar protein
|
increases expression
|
ISO
|
Nickel results in increased expression of NOP2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:159,618,894...159,630,697
Ensembl chr 4:159,618,966...159,630,697
|
|
| G
|
Nop56
|
NOP56 ribonucleoprotein
|
increases expression
|
ISO
|
Nickel results in increased expression of NOP56 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:137,926,187...137,934,971
Ensembl chr 3:137,929,646...137,934,959
|
|
| G
|
Nos1
|
nitric oxide synthase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NOS1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr12:44,276,011...44,456,371
Ensembl chr12:44,287,614...44,371,837
|
|
| G
|
Nos2
|
nitric oxide synthase 2
|
multiple interactions increases expression
|
EXP ISO
|
[Nickel co-treated with Cobalt co-treated with Tungsten] results in increased expression of NOS2 mRNA; [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of NOS2 mRNA [Nickel co-treated with IL1B protein] results in increased expression of NOS2 mRNA Nickel results in increased expression of NOS2 mRNA
|
CTD |
PMID:22198552 PMID:23788631 |
|
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
|
|
| G
|
Nos3
|
nitric oxide synthase 3
|
increases activity multiple interactions
|
ISO
|
Nickel results in increased activity of NOS3 protein [Particulate Matter co-treated with Nickel] results in decreased expression of [NOS3 protein binds to NOS3 protein]; Nickel promotes the reaction [Particulate Matter results in decreased phosphorylation of NOS3 protein]; Particulate Matter promotes the reaction [Nickel results in decreased expression of [NOS3 protein binds to NOS3 protein]] 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Nickel results in decreased expression of [NOS3 protein binds to NOS3 protein]]; Lipopolysaccharides promotes the reaction [Nickel results in decreased expression of [NOS3 protein binds to NOS3 protein]]; Nickel results in decreased expression of [NOS3 protein binds to NOS3 protein]
|
CTD |
PMID:12540486 PMID:23788629 |
|
NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664
|
|
| G
|
Nostrin
|
nitric oxide synthase trafficking
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NOSTRIN mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:74,312,594...74,378,852
Ensembl chr 3:74,312,647...74,396,455
|
|
| G
|
Notch4
|
notch receptor 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NOTCH4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr20:4,164,969...4,189,072
Ensembl chr20:4,161,730...4,189,072
|
|
| G
|
Npm3
|
nucleophosmin/nucleoplasmin, 3
|
increases expression
|
ISO
|
Nickel results in increased expression of NPM3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:254,544,664...254,546,649
Ensembl chr 1:254,544,664...254,546,649
|
|
| G
|
Npnt
|
nephronectin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NPNT mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 2:224,065,191...224,133,567
Ensembl chr 2:224,065,191...224,133,435
|
|
| G
|
Npr1
|
natriuretic peptide receptor 1
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of NPR1 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of NPR1 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 2:178,231,766...178,247,591
Ensembl chr 2:178,231,766...178,247,088
|
|
| G
|
Npr2
|
natriuretic peptide receptor 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NPR2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 5:62,678,197...62,697,360
Ensembl chr 5:62,678,367...62,697,343
|
|
| G
|
Npr3
|
natriuretic peptide receptor 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NPR3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:62,592,557...62,660,497
Ensembl chr 2:62,597,668...62,660,066
|
|
| G
|
Nprl3
|
NPR3-like, GATOR1 complex subunit
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NPRL3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:15,859,739...15,900,261
Ensembl chr10:15,859,789...15,902,332
|
|
| G
|
Npy
|
neuropeptide Y
|
decreases expression
|
EXP
|
Nickel results in decreased expression of NPY mRNA
|
CTD |
PMID:20682304 |
|
NCBI chr 4:80,212,111...80,219,310
Ensembl chr 4:80,212,111...80,219,310
|
|
| G
|
Npy1r
|
neuropeptide Y receptor Y1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NPY1R mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr16:27,804,416...27,814,070
Ensembl chr16:27,804,416...27,813,387
|
|
| G
|
Nqo1
|
NAD(P)H quinone dehydrogenase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of NQO1 mRNA
|
CTD |
PMID:19033392 |
|
NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
|
|
| G
|
Nr1d2
|
nuclear receptor subfamily 1, group D, member 2
|
increases expression
|
ISO
|
Nickel results in increased expression of NR1D2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr15:9,955,034...9,981,329
Ensembl chr15:9,954,906...9,981,330
|
|
| G
|
Nr1h3
|
nuclear receptor subfamily 1, group H, member 3
|
decreases expression multiple interactions
|
ISO EXP
|
Nickel results in decreased expression of NR1H3 mRNA [nickel sulfate results in increased abundance of Nickel] which results in decreased expression of NR1H3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 PMID:31734292 |
|
NCBI chr 3:97,614,616...97,632,053
Ensembl chr 3:97,614,616...97,624,532
|
|
| G
|
Nr3c2
|
nuclear receptor subfamily 3, group C, member 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NR3C2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr19:47,619,853...47,964,089
Ensembl chr19:47,619,853...47,964,078
|
|
| G
|
Nr4a1
|
nuclear receptor subfamily 4, group A, member 1
|
increases expression
|
ISO
|
Nickel results in increased expression of NR4A1 mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr 7:134,247,153...134,268,044
Ensembl chr 7:134,247,192...134,268,041
|
|
| G
|
Nr4a2
|
nuclear receptor subfamily 4, group A, member 2
|
increases expression
|
ISO
|
Nickel results in increased expression of NR4A2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 3:62,098,739...62,115,926
Ensembl chr 3:62,098,743...62,106,769
|
|
| G
|
Nr4a3
|
nuclear receptor subfamily 4, group A, member 3
|
increases expression
|
ISO
|
Nickel results in increased expression of NR4A3 mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr 5:67,157,141...67,198,287
Ensembl chr 5:67,157,375...67,198,285
|
|
| G
|
Nras
|
NRAS proto-oncogene, GTPase
|
increases expression
|
ISO
|
Nickel results in increased expression of NRAS mRNA
|
CTD |
PMID:20053437 PMID:24768652 PMID:25583101 |
|
NCBI chr 2:193,271,399...193,282,023
Ensembl chr 2:193,271,430...193,278,543
|
|
| G
|
Nrcam
|
neuronal cell adhesion molecule
|
increases expression
|
ISO
|
Nickel results in increased expression of NRCAM mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:67,129,723...67,425,510
Ensembl chr 6:67,129,801...67,430,539
|
|
| G
|
Nrep
|
neuronal regeneration related protein
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NREP mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr18:25,291,219...25,320,742
Ensembl chr18:25,291,219...25,320,742
|
|
| G
|
Nrf1
|
nuclear respiratory factor 1
|
multiple interactions
|
ISO
|
[nickel chloride results in increased abundance of Nickel] which results in decreased expression of NRF1 mRNA
|
CTD |
PMID:36794572 |
|
NCBI chr 4:59,632,366...59,738,166
Ensembl chr 4:59,632,372...59,738,353
|
|
| G
|
Nrg1
|
neuregulin 1
|
increases expression
|
ISO
|
Nickel results in increased expression of NRG1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr16:65,954,084...67,007,484
Ensembl chr16:65,953,865...66,999,849
|
|
| G
|
Nrg2
|
neuregulin 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NRG2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr18:27,890,578...28,072,538
Ensembl chr18:27,890,578...28,072,538
|
|
| G
|
Nrg3
|
neuregulin 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NRG3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr16:14,256,540...15,374,107
Ensembl chr16:14,257,148...15,374,147
|
|
| G
|
Nrip2
|
nuclear receptor interacting protein 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NRIP2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:163,359,592...163,370,144
Ensembl chr 4:163,360,665...163,370,141
|
|
| G
|
Nrk
|
Nik related kinase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NRK mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr X:107,159,154...107,256,417
Ensembl chr X:107,159,233...107,256,417
|
|
| G
|
Nrp2
|
neuropilin 2
|
increases expression
|
ISO
|
Nickel results in increased expression of NRP2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 9:71,616,602...71,731,869
Ensembl chr 9:71,616,657...71,731,871
|
|
| G
|
Nrros
|
negative regulator of reactive oxygen species
|
increases expression
|
ISO
|
Nickel results in increased expression of NRROS mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:82,133,608...82,151,160
Ensembl chr11:82,133,144...82,151,308
|
|
| G
|
Nrxn1
|
neurexin 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NRXN1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:8,931,360...10,077,381
Ensembl chr 6:8,935,523...10,077,374
|
|
| G
|
Nrxn3
|
neurexin 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NRXN3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 6:113,372,667...115,004,073
Ensembl chr 6:113,443,524...115,002,540
|
|
| G
|
Ns5atp4
|
NS5A transactivated protein 4
|
increases expression
|
ISO
|
Nickel results in increased expression of LTAP1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:177,792,070...177,804,943
Ensembl chr 2:177,791,958...177,804,942
|
|
| G
|
Nsd2
|
nuclear receptor binding SET domain protein 2
|
increases expression
|
ISO
|
Nickel results in increased expression of NSD2 mRNA
|
CTD |
PMID:18922574 PMID:25583101 |
|
NCBI chr14:81,057,727...81,135,866
Ensembl chr14:81,057,727...81,123,027
|
|
| G
|
Nsf
|
N-ethylmaleimide sensitive factor, vesicle fusing ATPase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NSF mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr10:89,227,937...89,357,383
Ensembl chr10:89,227,937...89,367,621
|
|
| G
|
Nsun4
|
NOP2/Sun RNA methyltransferase 4
|
increases expression
|
ISO
|
Nickel results in increased expression of NSUN4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:134,749,024...134,773,630
Ensembl chr 5:134,749,024...134,775,401
|
|
| G
|
Nsun7
|
NOP2/Sun RNA methyltransferase family member 7
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NSUN7 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:42,233,062...42,289,013
Ensembl chr14:42,233,062...42,288,958
|
|
| G
|
Nt5e
|
5' nucleotidase, ecto
|
increases expression
|
ISO
|
Nickel results in increased expression of NT5E mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:98,150,925...98,195,646
Ensembl chr 8:98,150,900...98,195,645
|
|
| G
|
Ntf4
|
neurotrophin 4
|
decreases expression
|
EXP
|
Nickel results in decreased expression of NTF4 mRNA
|
CTD |
PMID:19130878 |
|
NCBI chr 1:105,030,035...105,032,866
Ensembl chr 1:105,029,764...105,034,038
|
|
| G
|
Ntmt1
|
N-terminal Xaa-Pro-Lys N-methyltransferase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of NTMT1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:34,490,972...34,508,316
Ensembl chr 3:34,484,388...34,508,417
|
|
| G
|
Ntrk1
|
neurotrophic receptor tyrosine kinase 1
|
affects expression
|
EXP
|
Nickel affects the expression of NTRK1 mRNA
|
CTD |
PMID:19130878 |
|
NCBI chr 2:175,534,844...175,551,664
Ensembl chr 2:175,534,844...175,551,787
|
|
| G
|
Ntrk2
|
neurotrophic receptor tyrosine kinase 2
|
decreases expression
|
EXP
|
Nickel results in decreased expression of NTRK2 mRNA
|
CTD |
PMID:19130878 |
|
NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,564,570...5,874,628
|
|
| G
|
Ntrk3
|
neurotrophic receptor tyrosine kinase 3
|
decreases expression
|
EXP ISO
|
Nickel results in decreased expression of NTRK3 mRNA
|
CTD |
PMID:19130878 PMID:24768652 PMID:25583101 |
|
NCBI chr 1:141,526,192...141,913,575
Ensembl chr 1:141,542,569...141,913,004
|
|
| G
|
Nts
|
neurotensin
|
increases expression
|
EXP
|
Nickel results in increased expression of NTS mRNA
|
CTD |
PMID:20682304 |
|
NCBI chr 7:39,451,484...39,460,888
Ensembl chr 7:39,451,073...39,460,961
|
|
| G
|
Nuak1
|
NUAK family kinase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NUAK1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:21,217,729...21,289,608
Ensembl chr 7:21,217,681...21,289,354
|
|
| G
|
Nub1
|
negative regulator of ubiquitin-like proteins 1
|
increases expression
|
ISO
|
Nickel results in increased expression of NUB1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:11,335,376...11,366,263
Ensembl chr 4:11,335,883...11,366,462
|
|
| G
|
Nubp1
|
NUBP iron-sulfur cluster assembly factor 1
|
increases expression
|
ISO
|
Nickel results in increased expression of NUBP1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr10:5,766,157...5,777,648
Ensembl chr10:5,766,157...5,786,422
|
|
| G
|
Nudcd1
|
NudC domain containing 1
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of NUDCD1 mRNA Nickel results in increased expression of NUDCD1 mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 7:77,436,035...77,480,651
Ensembl chr 7:77,436,036...77,480,575
|
|
| G
|
Nudt4
|
nudix hydrolase 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NUDT4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:32,074,978...32,091,491
Ensembl chr 7:32,075,002...32,091,491
|
|
| G
|
Nudt5
|
nudix hydrolase 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NUDT5 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr17:77,345,041...77,368,308
Ensembl chr17:77,345,045...77,368,308
|
|
| G
|
Nudt7
|
nudix hydrolase 7
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NUDT7 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr19:59,034,808...59,049,148
Ensembl chr19:59,034,839...59,063,994
|
|
| G
|
Nuf2
|
NUF2 component of NDC80 kinetochore complex
|
increases expression
|
ISO
|
Nickel results in increased expression of NUF2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:84,226,448...84,290,957
Ensembl chr13:84,226,509...84,255,598
|
|
| G
|
Numa1
|
nuclear mitotic apparatus protein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of NUMA1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:165,709,893...165,784,848
Ensembl chr 1:165,709,905...165,784,848
|
|
| G
|
Numb
|
NUMB, endocytic adaptor protein
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NUMB mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 6:109,162,499...109,284,527
Ensembl chr 6:109,162,499...109,284,463
|
|
| G
|
Nup160
|
nucleoporin 160
|
increases expression
|
ISO
|
Nickel results in increased expression of NUP160 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:97,120,723...97,183,227
Ensembl chr 3:97,121,628...97,180,720
|
|
| G
|
Nup210
|
nucleoporin 210
|
increases expression
|
ISO
|
Nickel results in increased expression of NUP210 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:125,068,736...125,167,238
Ensembl chr 4:125,068,736...125,167,047
|
|
| G
|
Nup214
|
nucleoporin 214
|
increases expression multiple interactions
|
ISO EXP
|
Nickel results in increased expression of NUP214 mRNA [nickel sulfate results in increased abundance of Nickel] which results in increased expression of NUP214 mRNA
|
CTD |
PMID:24768652 PMID:25583101 PMID:31734292 |
|
NCBI chr 3:35,652,841...35,738,323
Ensembl chr 3:35,652,858...35,739,192
|
|
| G
|
Nup43
|
nucleoporin 43
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NUP43 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 1:3,964,814...3,978,277
Ensembl chr 1:3,938,825...3,978,277
|
|
| G
|
Nup50
|
nucleoporin 50
|
increases expression
|
ISO
|
Nickel results in increased expression of NUP50 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:117,927,882...117,945,155
Ensembl chr 7:117,925,716...117,946,959
|
|
| G
|
Nup98
|
nucleoporin 98 and 96 precursor
|
increases expression
|
ISO
|
Nickel results in increased expression of NUP98 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:165,906,405...166,003,366
Ensembl chr 1:165,906,405...166,003,366
|
|
| G
|
Nusap1
|
nucleolar and spindle associated protein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of NUSAP1 mRNA
|
CTD |
PMID:19031421 |
|
NCBI chr 3:127,057,220...127,092,779
Ensembl chr 3:127,057,265...127,087,237
|
|
| G
|
Nxt1
|
nuclear transport factor 2-like export factor 1
|
increases expression
|
ISO
|
Nickel results in increased expression of NXT1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:156,562,121...156,565,043
Ensembl chr 3:156,560,556...156,565,996
|
|
| G
|
Nynrin
|
NYN domain and retroviral integrase containing
|
decreases expression
|
ISO
|
Nickel results in decreased expression of NYNRIN mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr15:33,302,778...33,325,120
Ensembl chr15:33,295,954...33,324,383
|
|
| G
|
Oas1a
|
2'-5' oligoadenylate synthetase 1A
|
increases expression decreases expression
|
ISO
|
Nickel results in increased expression of OAS1 mRNA Nickel results in decreased expression of OAS1 mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr12:41,330,423...41,341,130
Ensembl chr12:41,285,211...41,341,128
|
|
| G
|
Oas2
|
2'-5' oligoadenylate synthetase 2
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of OAS2 mRNA Nickel results in increased expression of OAS2 mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr12:41,464,568...41,492,036
Ensembl chr12:41,467,315...41,495,881
|
|
| G
|
Oas3
|
2'-5'-oligoadenylate synthetase 3
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of OAS3 mRNA Nickel results in increased expression of OAS3 mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr12:41,439,645...41,463,392
Ensembl chr12:41,439,643...41,464,420
|
|
| G
|
Oasl
|
2'-5'-oligoadenylate synthetase-like
|
increases expression
|
ISO
|
Nickel results in increased expression of OASL mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr12:47,343,551...47,356,509
Ensembl chr12:47,343,551...47,356,483
|
|
| G
|
Oaz3
|
ornithine decarboxylase antizyme 3
|
increases expression
|
ISO
|
Nickel results in increased expression of OAZ3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:184,762,242...184,765,176
Ensembl chr 2:184,762,245...184,771,428
|
|
| G
|
Obp2a
|
odorant binding protein 2A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of OBP2A mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:28,904,024...28,907,391
Ensembl chr 3:28,902,876...28,907,389
|
|
| G
|
Obp2b
|
odorant binding protein 2B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of OBP2B mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:28,960,375...28,983,394
Ensembl chr 3:28,980,186...28,983,370
|
|
| G
|
Obsl1
|
obscurin like cytoskeletal adaptor 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of OBSL1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:84,416,447...84,442,415
Ensembl chr 9:84,416,240...84,442,415
|
|
| G
|
Oca2
|
OCA2 melanosomal transmembrane protein
|
decreases expression
|
ISO
|
Nickel results in decreased expression of OCA2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 1:116,252,026...116,581,838
Ensembl chr 1:116,251,796...116,581,838
|
|
| G
|
Ocln
|
occludin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of OCLN mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:33,391,303...33,430,411
|
|
| G
|
Odc1
|
ornithine decarboxylase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of ODC1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:46,058,463...46,065,146
|
|
| G
|
Ogdh
|
oxoglutarate dehydrogenase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of OGDH mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr14:85,363,949...85,431,405
Ensembl chr14:85,364,014...85,432,271
|
|
| G
|
Ogfod1
|
2-oxoglutarate and iron-dependent oxygenase domain containing 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of OGFOD1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr19:10,950,950...10,980,519
Ensembl chr19:10,950,060...10,980,519
|
|
| G
|
Ogg1
|
8-oxoguanine DNA glycosylase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of OGG1 mRNA
|
CTD |
PMID:22641096 |
|
NCBI chr 4:148,030,237...148,037,599
Ensembl chr 4:148,030,349...148,037,604
|
|
| G
|
Ogn
|
osteoglycin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of OGN mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr17:15,238,500...15,259,167
Ensembl chr17:15,238,500...15,259,252
|
|
| G
|
Olfm4
|
olfactomedin 4
|
increases expression
|
ISO
|
Nickel results in increased expression of OLFM4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr15:61,790,889...61,838,773
Ensembl chr15:61,671,271...61,838,764
|
|
| G
|
Olfml1
|
olfactomedin-like 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of OLFML1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:170,889,912...170,914,300
Ensembl chr 1:170,889,980...170,915,762
|
|
| G
|
Olfml2a
|
olfactomedin-like 2A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of OLFML2A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:43,098,299...43,127,621
Ensembl chr 3:43,098,299...43,127,621
|
|
| G
|
Olfml3
|
olfactomedin-like 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of OLFML3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:193,932,665...193,935,494
Ensembl chr 2:193,932,665...193,935,494
|
|
| G
|
Omd
|
osteomodulin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of OMD mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr17:15,266,646...15,274,870
Ensembl chr17:15,266,646...15,274,870
|
|
| G
|
Oprpn
|
opiorphin prepropeptide
|
decreases expression
|
ISO
|
Nickel results in decreased expression of OPRPN mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr14:19,986,575...20,001,589
Ensembl chr14:19,986,575...20,001,589
|
|
| G
|
Or4k2
|
olfactory receptor family 4 subfamily K member 2
|
increases expression
|
ISO
|
Nickel results in increased expression of OR4K2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr15:25,878,316...25,879,269
Ensembl chr15:25,878,316...25,879,272
|
|
| G
|
Or51e1
|
olfactory receptor family 51 subfamily E member 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of OR51E1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:166,554,112...166,564,147
Ensembl chr 1:166,554,061...166,564,105
|
|
| G
|
Orai2
|
ORAI calcium release-activated calcium modulator 2
|
increases expression
|
ISO
|
Nickel results in increased expression of ORAI2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr12:26,136,922...26,157,041
Ensembl chr12:26,132,193...26,157,041
|
|
| G
|
Ormdl2
|
ORMDL sphingolipid biosynthesis regulator 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ORMDL2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 7:1,832,368...1,835,501
Ensembl chr 7:1,832,368...1,836,223
|
|
| G
|
Osbpl11
|
oxysterol binding protein-like 11
|
decreases expression
|
ISO
|
Nickel results in decreased expression of OSBPL11 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr11:81,038,759...81,121,887
Ensembl chr11:81,038,985...81,101,299
|
|
| G
|
Osbpl1a
|
oxysterol binding protein-like 1A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of OSBPL1A mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr18:4,178,734...4,383,511
Ensembl chr18:4,179,631...4,369,421
|
|
| G
|
Osbpl3
|
oxysterol binding protein-like 3
|
increases expression
|
ISO
|
Nickel results in increased expression of OSBPL3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:80,677,383...80,854,169
Ensembl chr 4:80,677,390...80,854,169
|
|
| G
|
Oscar
|
osteoclast associated Ig-like receptor
|
increases expression
|
ISO
|
Nickel results in increased expression of OSCAR mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:74,521,626...74,529,119
Ensembl chr 1:74,515,001...74,529,119
|
|
| G
|
Osm
|
oncostatin M
|
increases expression
|
ISO
|
Nickel results in increased expression of OSM mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:83,327,202...83,332,073
Ensembl chr14:83,327,554...83,331,827
|
|
| G
|
Osmr
|
oncostatin M receptor
|
increases expression
|
ISO
|
Nickel results in increased expression of OSMR mRNA
|
CTD |
PMID:12540486 PMID:24768652 PMID:25583101 |
|
NCBI chr 2:57,634,517...57,688,802
Ensembl chr 2:57,634,517...57,688,561
|
|
| G
|
Osr1
|
odd-skipped related transcription factor 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of OSR1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 6:38,088,688...38,100,010
Ensembl chr 6:38,093,011...38,100,021
|
|
| G
|
Osr2
|
odd-skipped related transcription factor 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of OSR2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:68,372,500...68,380,195
Ensembl chr 7:68,373,049...68,380,805
|
|
| G
|
Ostc
|
oligosaccharyltransferase complex non-catalytic subunit
|
increases expression
|
ISO
|
Nickel results in increased expression of OSTC mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:221,924,727...221,940,253
Ensembl chr 2:221,874,948...221,940,267
|
|
| G
|
Otud7b
|
OTU deubiquitinase 7B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of OTUD7B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:186,350,811...186,411,461
Ensembl chr 2:186,350,798...186,409,440
|
|
| G
|
Ovol2
|
ovo-like zinc finger 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of OVOL2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:152,130,767...152,160,487
Ensembl chr 3:152,130,767...152,160,487
|
|
| G
|
Oxgr1
|
oxoglutarate receptor 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of OXGR1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr15:103,551,338...103,573,611
Ensembl chr15:103,552,861...103,553,874
|
|
| G
|
Oxr1
|
oxidation resistance 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of OXR1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:74,413,609...74,850,487
Ensembl chr 7:74,413,590...74,850,487
|
|
| G
|
P2rx1
|
purinergic receptor P2X 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of P2RX1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:58,117,107...58,132,167
Ensembl chr10:58,117,088...58,132,164
|
|
| G
|
P2rx5
|
purinergic receptor P2X 5
|
increases expression
|
ISO
|
Nickel results in increased expression of P2RX5 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:58,276,329...58,291,108
Ensembl chr10:58,276,257...58,287,935
|
|
| G
|
P2rx7
|
purinergic receptor P2X 7
|
decreases expression
|
ISO
|
Nickel results in decreased expression of P2RX7 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr12:39,550,531...39,594,984
Ensembl chr12:39,540,567...39,595,193
|
|
| G
|
P2ry1
|
purinergic receptor P2Y1
|
increases expression
|
ISO
|
Nickel results in increased expression of P2RY1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:147,391,661...147,397,870
Ensembl chr 2:147,390,681...147,398,027
|
|
| G
|
P2ry10
|
P2Y receptor family member 10
|
increases expression
|
ISO
|
Nickel results in increased expression of P2RY10 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr X:76,184,064...76,279,996
Ensembl chr X:76,184,001...76,280,953
|
|
| G
|
P2ry13
|
purinergic receptor P2Y13
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of P2RY13 mRNA Nickel results in increased expression of P2RY13 mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 2:145,620,321...145,624,730
Ensembl chr 2:145,619,655...145,622,787
|
|
| G
|
P2ry2
|
purinergic receptor P2Y2
|
increases expression
|
ISO
|
Nickel results in increased expression of P2RY2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:164,764,119...164,779,578
Ensembl chr 1:164,759,213...164,781,852
|
|
| G
|
P2ry6
|
pyrimidinergic receptor P2Y6
|
increases expression
|
ISO
|
Nickel results in increased expression of P2RY6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:164,707,188...164,742,689
Ensembl chr 1:164,706,116...164,743,588
|
|
| G
|
Pacc1
|
proton activated chloride channel 1
|
increases expression
|
ISO
|
Nickel results in increased expression of PACC1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:105,435,772...105,460,877
Ensembl chr13:105,435,799...105,461,095
|
|
| G
|
Padi2
|
peptidyl arginine deiminase 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PADI2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:158,492,087...158,534,662
Ensembl chr 5:158,492,066...158,534,662
|
|
| G
|
Padi3
|
peptidyl arginine deiminase 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PADI3 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 5:158,372,764...158,400,193
Ensembl chr 5:158,372,764...158,400,193
|
|
| G
|
Pag1
|
phosphoprotein membrane anchor with glycosphingolipid microdomains 1
|
increases expression
|
ISO
|
Nickel results in increased expression of PAG1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:93,842,747...93,984,314
Ensembl chr 2:93,964,594...93,977,227
|
|
| G
|
Paics
|
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of PAICS mRNA Nickel results in increased expression of PAICS mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr14:31,553,355...31,586,843
Ensembl chr14:31,553,357...31,587,027
|
|
| G
|
Paip2b
|
poly(A) binding protein interacting protein 2B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PAIP2B mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:117,849,625...117,881,021
Ensembl chr 4:117,839,367...117,881,006
|
|
| G
|
Pak1
|
p21 (RAC1) activated kinase 1
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of PAK1 mRNA Nickel results in increased expression of PAK1 mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr 1:161,522,399...161,637,623
Ensembl chr 1:161,491,847...161,637,612
|
|
| G
|
Pak2
|
p21 (RAC1) activated kinase 2
|
increases expression
|
ISO
|
Nickel results in increased expression of PAK2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr11:82,212,896...82,273,803
Ensembl chr11:82,212,951...82,273,803
|
|
| G
|
Pak3
|
p21 (RAC1) activated kinase 3
|
increases expression decreases expression
|
ISO
|
Nickel results in increased expression of PAK3 mRNA Nickel results in decreased expression of PAK3 mRNA
|
CTD |
PMID:19031421 PMID:25583101 |
|
NCBI chr X:111,912,967...112,171,037
Ensembl chr X:111,913,059...112,165,035
|
|
| G
|
Palm
|
paralemmin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PALM mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:10,537,252...10,563,346
Ensembl chr 7:10,537,277...10,563,007
|
|
| G
|
Palmd
|
palmdelphin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PALMD mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:207,574,413...207,626,239
Ensembl chr 2:207,574,249...207,626,239
|
|
| G
|
Pamr1
|
peptidase domain containing associated with muscle regeneration 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PAMR1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:109,340,411...109,443,595
Ensembl chr 3:109,341,476...109,443,585
|
|
| G
|
Pank1
|
pantothenate kinase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PANK1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:241,737,371...241,808,126
Ensembl chr 1:241,741,083...241,807,824
|
|
| G
|
Pank2
|
pantothenate kinase 2
|
increases expression
|
ISO
|
Nickel results in increased expression of PANK2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:138,936,448...138,974,196
Ensembl chr 3:138,936,452...138,974,194
|
|
| G
|
Panx1
|
Pannexin 1
|
increases expression
|
ISO
|
Nickel results in increased expression of PANX1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:20,128,783...20,171,200
Ensembl chr 8:20,132,165...20,171,200
|
|
| G
|
Panx2
|
pannexin 2
|
increases expression
|
ISO
|
Nickel results in increased expression of PANX2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:122,018,937...122,032,009
Ensembl chr 7:122,018,937...122,032,004
|
|
| G
|
Papln
|
papilin, proteoglycan-like sulfated glycoprotein
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PAPLN mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:109,129,268...109,163,300
Ensembl chr 6:109,129,261...109,161,483
|
|
| G
|
Papss2
|
3'-phosphoadenosine 5'-phosphosulfate synthase 2
|
increases expression
|
ISO
|
Nickel results in increased expression of PAPSS2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:239,867,597...239,952,614
Ensembl chr 1:239,867,574...239,952,616
|
|
| G
|
Paqr8
|
progestin and adipoQ receptor family member 8
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PAQR8 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 9:30,808,921...30,858,599
Ensembl chr 9:30,808,923...30,861,043
|
|
| G
|
Pard3
|
par-3 family cell polarity regulator
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PARD3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr19:71,977,420...72,527,273
Ensembl chr19:71,977,470...72,526,941
|
|
| G
|
Pard3b
|
par-3 family cell polarity regulator beta
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PARD3B mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 9:70,532,358...71,561,044
Ensembl chr 9:70,532,644...71,560,554
|
|
| G
|
Parg
|
poly (ADP-ribose) glycohydrolase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PARG mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr16:7,442,696...7,550,585
Ensembl chr16:7,442,726...7,550,584
|
|
| G
|
Parp1
|
poly (ADP-ribose) polymerase 1
|
decreases expression multiple interactions affects binding
|
ISO
|
Nickel results in decreased expression of PARP1 mRNA [Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased cleavage of PARP1 protein; Luteolin inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased cleavage of PARP1 protein] PARP1 protein modified form binds to Nickel
|
CTD |
PMID:23195993 PMID:25549802 PMID:29115570 |
|
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
|
|
| G
|
Parp10
|
poly (ADP-ribose) polymerase family, member 10
|
increases expression
|
ISO
|
Nickel results in increased expression of PARP10 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:109,829,721...109,839,054
Ensembl chr 7:109,829,722...109,843,566
|
|
| G
|
Parp11
|
poly (ADP-ribose) polymerase family, member 11
|
increases expression
|
ISO
|
Nickel results in increased expression of PARP11 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:161,984,192...162,030,550
Ensembl chr 4:161,991,042...162,030,557
|
|
| G
|
Parp12
|
poly (ADP-ribose) polymerase family, member 12
|
increases expression
|
ISO
|
Nickel results in increased expression of PARP12 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:68,793,411...68,851,214
Ensembl chr 4:68,806,100...68,850,541
|
|
| G
|
Parp14
|
poly (ADP-ribose) polymerase family, member 14
|
increases expression
|
ISO
|
Nickel results in increased expression of PARP14 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:78,408,134...78,440,201
Ensembl chr11:78,408,058...78,440,195
|
|
| G
|
Parp4
|
poly (ADP-ribose) polymerase family, member 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PARP4 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr15:34,806,203...34,908,492
Ensembl chr15:34,816,701...34,944,433
|
|
| G
|
Parp8
|
poly (ADP-ribose) polymerase family, member 8
|
increases expression
|
ISO
|
Nickel results in increased expression of PARP8 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:50,408,404...50,581,513
Ensembl chr 2:50,408,404...50,581,233
|
|
| G
|
Parp9
|
poly (ADP-ribose) polymerase family, member 9
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of PARP9 mRNA Nickel results in increased expression of PARP9 mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr11:78,286,282...78,320,409
Ensembl chr11:78,286,287...78,320,608
|
|
| G
|
Parpbp
|
PARP1 binding protein
|
increases expression
|
ISO
|
Nickel results in increased expression of PARPBP mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:24,398,897...24,468,330
Ensembl chr 7:24,398,897...24,464,744
|
|
| G
|
Parva
|
parvin, alpha
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PARVA mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:175,981,725...176,139,523
Ensembl chr 1:175,981,432...176,139,526
|
|
| G
|
Parvg
|
parvin, gamma
|
increases expression
|
ISO
|
Nickel results in increased expression of PARVG mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:117,336,160...117,366,341
Ensembl chr 7:117,336,187...117,362,155
|
|
| G
|
Pask
|
PAS domain containing serine/threonine kinase
|
increases expression
|
ISO
|
Nickel results in increased expression of PASK mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 9:101,291,673...101,333,288
Ensembl chr 9:101,291,676...101,332,504
|
|
| G
|
Patl1
|
PAT1 homolog 1, processing body mRNA decay factor
|
increases expression
|
ISO
|
Nickel results in increased expression of PATL1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:218,255,801...218,287,662
Ensembl chr 1:218,255,848...218,287,657
|
|
| G
|
Pax1
|
paired box 1
|
increases expression
|
ISO
|
Nickel results in increased expression of PAX1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:155,244,961...155,254,836
Ensembl chr 3:155,245,529...155,254,836
|
|
| G
|
Pbk
|
PDZ binding kinase
|
increases expression
|
ISO
|
Nickel results in increased expression of PBK mRNA
|
CTD |
PMID:19031421 PMID:25583101 |
|
NCBI chr15:44,198,506...44,209,572
Ensembl chr15:44,198,544...44,209,570
|
|
| G
|
Pbx1
|
PBX homeobox 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PBX1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:82,811,664...83,121,447
Ensembl chr13:82,812,131...83,121,066
|
|
| G
|
Pc
|
pyruvate carboxylase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PC mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:211,228,708...211,327,792
Ensembl chr 1:211,228,731...211,329,940
|
|
| G
|
Pcdh12
|
protocadherin 12
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PCDH12 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr18:30,354,910...30,370,485
Ensembl chr18:30,354,910...30,370,485
|
|
| G
|
Pcdh19
|
protocadherin 19
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PCDH19 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr X:101,061,002...101,166,777
Ensembl chr X:101,065,263...101,165,269
|
|
| G
|
Pcdh20
|
protocadherin 20
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PCDH20 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr15:70,834,042...70,840,298
Ensembl chr15:70,834,042...70,840,298
|
|
| G
|
Pcdh7
|
protocadherin 7
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of PCDH7 mRNA Nickel results in increased expression of PCDH7 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:56,684,817...57,114,976
Ensembl chr14:56,687,725...57,112,665
|
|
| G
|
Pcdh8
|
protocadherin 8
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PCDH8 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr15:61,607,521...61,612,090
Ensembl chr15:61,607,521...61,612,097
|
|
| G
|
Pcdh9
|
protocadherin 9
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PCDH9 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr15:75,748,472...76,646,644 NCBI chr15:76,078,024...76,127,778
Ensembl chr15:75,749,278...76,645,302
|
|
| G
|
Pcdha3
|
protocadherin alpha 3
|
increases expression
|
ISO
|
Nickel results in increased expression of PCDHA3 mRNA
|
CTD |
PMID:23195993 |
|
|
|
| G
|
Pcdhb5
|
protocadherin beta 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PCDHB4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr18:29,302,466...29,305,048
|
|
| G
|
Pcdhga4
|
protocadherin gamma subfamily A, 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PCDHGA4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr18:29,760,777...29,794,877
|
|
| G
|
Pced1b
|
PC-esterase domain containing 1B
|
increases expression
|
ISO
|
Nickel results in increased expression of PCED1B mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:130,273,531...130,451,727
Ensembl chr 7:130,270,554...130,410,365
|
|
| G
|
Pcgf5
|
polycomb group ring finger 5
|
increases expression
|
ISO
|
Nickel results in increased expression of PCGF5 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:243,476,450...243,592,603
Ensembl chr 1:243,476,261...243,587,869
|
|
| G
|
Pclaf
|
PCNA clamp associated factor
|
increases expression
|
ISO
|
Nickel results in increased expression of PCLAF mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:75,311,028...75,328,108
Ensembl chr 8:75,315,707...75,328,106
|
|
| G
|
Pclo
|
piccolo (presynaptic cytomatrix protein)
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PCLO mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:20,646,604...21,005,171
Ensembl chr 4:20,646,604...21,005,111
|
|
| G
|
Pcna
|
proliferating cell nuclear antigen
|
increases expression
|
ISO
|
Nickel results in increased expression of PCNA mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
|
|
| G
|
Pcnx1
|
pecanex 1
|
increases expression
|
ISO
|
Nickel results in increased expression of PCNX1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:107,296,704...107,433,576
Ensembl chr 6:107,296,792...107,432,452
|
|
| G
|
Pcnx4
|
pecanex 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PCNX4 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 6:96,860,960...96,906,319
Ensembl chr 6:96,869,591...96,906,317
|
|
| G
|
Pcp4
|
Purkinje cell protein 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PCP4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:49,229,185...49,331,186
Ensembl chr11:49,270,186...49,331,186
|
|
| G
|
Pcsk1
|
proprotein convertase subtilisin/kexin type 1
|
increases expression
|
ISO
|
Nickel results in increased expression of PCSK1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:6,130,045...6,176,974
Ensembl chr 2:6,129,592...6,176,974
|
|
| G
|
Pcsk2
|
proprotein convertase subtilisin/kexin type 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PCSK2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:151,333,938...151,636,628
Ensembl chr 3:151,333,234...151,638,849
|
|
| G
|
Pcsk7
|
proprotein convertase subtilisin/kexin type 7
|
increases expression
|
ISO
|
Nickel results in increased expression of PCSK7 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:55,098,821...55,121,416
Ensembl chr 8:55,098,806...55,121,382
|
|
| G
|
Pctp
|
phosphatidylcholine transfer protein
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PCTP mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:75,305,999...75,351,919
Ensembl chr10:75,305,999...75,326,432
|
|
| G
|
Pcyox1
|
prenylcysteine oxidase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PCYOX1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 4:120,389,545...120,400,382
Ensembl chr 4:120,388,180...120,400,382
|
|
| G
|
Pcyt1a
|
phosphate cytidylyltransferase 1A, choline
|
increases expression
|
ISO
|
Nickel results in increased expression of PCYT1A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:81,818,914...81,862,623
Ensembl chr11:81,819,285...81,862,395
|
|
| G
|
Pdcd11
|
programmed cell death 11
|
increases expression
|
ISO
|
Nickel results in increased expression of PDCD11 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:255,922,198...255,963,336
Ensembl chr 1:255,922,225...255,963,336
|
|
| G
|
Pdcd2l
|
programmed cell death 2-like
|
increases expression
|
ISO
|
Nickel results in increased expression of PDCD2L mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:95,947,476...95,959,738
Ensembl chr 1:95,947,476...95,959,906
|
|
| G
|
Pde1a
|
phosphodiesterase 1A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PDE1A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:85,152,053...85,432,289
Ensembl chr 3:85,154,184...85,519,212
|
|
| G
|
Pde1c
|
phosphodiesterase 1C
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PDE1C mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:86,629,074...87,108,147
Ensembl chr 4:86,626,282...87,193,259
|
|
| G
|
Pde2a
|
phosphodiesterase 2A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PDE2A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:165,235,623...165,327,466
Ensembl chr 1:165,235,623...165,327,466
|
|
| G
|
Pde3b
|
phosphodiesterase 3B
|
increases expression
|
ISO
|
Nickel results in increased expression of PDE3B mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 1:178,041,207...178,204,503
Ensembl chr 1:178,041,207...178,204,503
|
|
| G
|
Pde4b
|
phosphodiesterase 4B
|
increases expression
|
ISO
|
Nickel results in increased expression of PDE4B mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:122,028,956...122,598,267
Ensembl chr 5:122,135,174...122,598,267
|
|
| G
|
Pde4dip
|
phosphodiesterase 4D interacting protein
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PDE4DIP mRNA
|
CTD |
PMID:12540486 PMID:25583101 |
|
NCBI chr 2:187,982,002...188,178,937
Ensembl chr 2:187,981,878...188,178,869
|
|
| G
|
Pde5a
|
phosphodiesterase 5A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PDE5A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:213,542,822...213,687,638
Ensembl chr 2:213,542,923...213,684,298
|
|
| G
|
Pde6a
|
phosphodiesterase 6A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PDE6A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr18:56,947,249...57,019,015
Ensembl chr18:56,947,249...57,019,015
|
|
| G
|
Pde7a
|
phosphodiesterase 7A
|
increases expression
|
ISO
|
Nickel results in increased expression of PDE7A mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:103,631,655...103,723,057
Ensembl chr 2:103,634,594...103,722,890
|
|
| G
|
Pde7b
|
phosphodiesterase 7B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PDE7B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:16,994,072...17,312,828
Ensembl chr 1:17,002,286...17,312,456
|
|
| G
|
Pde8b
|
phosphodiesterase 8B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PDE8B mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:28,009,841...28,244,050
Ensembl chr 2:28,011,359...28,244,327
|
|
| G
|
Pde9a
|
phosphodiesterase 9A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PDE9A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr20:9,471,136...9,564,286
Ensembl chr20:9,471,167...9,564,286
|
|
| G
|
Pdgfb
|
platelet derived growth factor subunit B
|
multiple interactions
|
EXP
|
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Nickel analog promotes the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Nickel analog promotes the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [PDGFB protein promotes the reaction [Nickel analog results in increased expression of CCL2 mRNA]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [PDGFB protein promotes the reaction [Nickel analog results in increased expression of CCL2 protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [PDGFB protein promotes the reaction [Nickel analog results in increased expression of CXCL10 mRNA]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [PDGFB protein promotes the reaction [Nickel analog results in increased expression of CXCL10 protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [PDGFB protein promotes the reaction [Nickel analog results in increased expression of HIF1A protein]]; Acetylcysteine inhibits the reaction [Nickel analog promotes the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein]]; Acetylcysteine inhibits the reaction [Nickel analog promotes the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein]]; Acetylcysteine inhibits the reaction [PDGFB protein promotes the reaction [Nickel analog results in increased expression of CCL2 protein]]; Acetylcysteine inhibits the reaction [PDGFB protein promotes the reaction [Nickel analog results in increased expression of HIF1A protein]]; Nickel analog promotes the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein]; Nickel analog promotes the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein]; PDGFB protein promotes the reaction [Nickel analog results in increased expression of CCL2 mRNA]; PDGFB protein promotes the reaction [Nickel analog results in increased expression of CCL2 protein]; PDGFB protein promotes the reaction [Nickel analog results in increased expression of CXCL10 mRNA]; PDGFB protein promotes the reaction [Nickel analog results in increased expression of CXCL10 protein]; PDGFB protein promotes the reaction [Nickel analog results in increased expression of HIF1A protein]
|
CTD |
PMID:22700867 |
|
NCBI chr 7:113,419,882...113,438,343
Ensembl chr 7:113,420,710...113,438,343
|
|
| G
|
Pdgfd
|
platelet derived growth factor D
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PDGFD mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:11,773,335...12,007,277
Ensembl chr 8:11,773,475...12,007,271
|
|
| G
|
Pdia4
|
protein disulfide isomerase family A, member 4
|
increases expression
|
ISO
|
Nickel results in increased expression of PDIA4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:78,134,144...78,153,191
Ensembl chr 4:78,134,144...78,153,191
|
|
| G
|
Pdk3
|
pyruvate dehydrogenase kinase 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PDK3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:62,480,535...62,547,371
Ensembl chr X:62,480,535...62,547,371
|
|
| G
|
Pdk4
|
pyruvate dehydrogenase kinase 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PDK4 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 4:34,558,327...34,568,329
Ensembl chr 4:34,556,330...34,568,381
|
|
| G
|
Pdlim5
|
PDZ and LIM domain 5
|
increases expression
|
ISO
|
Nickel results in increased expression of PDLIM5 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 2:233,625,478...233,793,582
Ensembl chr 2:233,628,503...233,793,528
|
|
| G
|
Pdpn
|
podoplanin
|
increases expression
|
ISO
|
Nickel results in increased expression of PDPN mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:160,884,995...160,919,112
Ensembl chr 5:160,884,993...160,925,637
|
|
| G
|
Pdss1
|
decaprenyl diphosphate synthase subunit 1
|
increases expression
|
ISO
|
Nickel results in increased expression of PDSS1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr17:89,964,768...90,006,819
Ensembl chr17:89,968,034...90,006,817
|
|
| G
|
Pdss2
|
decaprenyl diphosphate synthase subunit 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PDSS2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr20:48,291,788...48,520,846
Ensembl chr20:48,291,797...48,535,689
|
|
| G
|
Pdzd2
|
PDZ domain containing 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PDZD2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:63,111,650...63,497,520
Ensembl chr 2:63,111,650...63,497,478
|
|
| G
|
Pdzk1
|
PDZ domain containing 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PDZK1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 2:187,064,995...187,096,348
Ensembl chr 2:187,065,013...187,096,806
|
|
| G
|
Pdzk1ip1
|
PDZK1 interacting protein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of PDZK1IP1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:133,841,586...133,859,894
Ensembl chr 5:133,841,313...133,859,893
|
|
| G
|
Pdzrn4
|
PDZ domain containing RING finger 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PDZRN4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:125,696,448...125,844,965
Ensembl chr 7:125,696,448...125,844,965
|
|
| G
|
Pear1
|
platelet endothelial aggregation receptor 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PEAR1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:175,504,184...175,531,969
Ensembl chr 2:175,505,550...175,525,322
|
|
| G
|
Pecr
|
peroxisomal trans-2-enoyl-CoA reductase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PECR mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:81,347,170...81,375,809
Ensembl chr 9:81,347,173...81,375,806
|
|
| G
|
Peg10
|
paternally expressed 10
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PEG10 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:33,809,026...33,822,224
Ensembl chr 4:33,817,190...33,819,166 Ensembl chr 4:33,817,190...33,819,166
|
|
| G
|
Peg3
|
paternally expressed 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PEG3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:76,130,965...76,157,774
Ensembl chr 1:76,130,948...76,157,743
|
|
| G
|
Peli1
|
pellino E3 ubiquitin protein ligase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of PELI1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr14:99,455,970...99,510,474
Ensembl chr14:99,455,811...99,510,466
|
|
| G
|
Peli2
|
pellino E3 ubiquitin protein ligase family member 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PELI2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr15:23,872,984...24,017,448
Ensembl chr15:23,872,984...24,014,817
|
|
| G
|
Pelo
|
pelota mRNA surveillance and ribosome rescue factor
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PELO mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:48,530,902...48,532,670
Ensembl chr 2:48,530,907...48,532,761
|
|
| G
|
Penk
|
proenkephalin
|
decreases expression
|
EXP
|
Nickel results in decreased expression of PENK mRNA
|
CTD |
PMID:20682304 |
|
NCBI chr 5:21,981,381...21,987,074
Ensembl chr 5:21,981,382...21,986,705
|
|
| G
|
Per1
|
period circadian regulator 1
|
increases expression
|
ISO
|
Nickel results in increased expression of PER1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr10:54,299,002...54,313,804
Ensembl chr10:54,302,641...54,314,211
|
|
| G
|
Per3
|
period circadian regulator 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PER3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:166,740,914...166,778,243
Ensembl chr 5:166,743,050...166,777,999
|
|
| G
|
Pex11a
|
peroxisomal biogenesis factor 11 alpha
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PEX11A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:143,089,410...143,096,491
Ensembl chr 1:143,089,410...143,096,645
|
|
| G
|
Pex11b
|
peroxisomal biogenesis factor 11 beta
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PEX11B mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 2:186,858,222...186,869,814
Ensembl chr 2:186,860,912...186,869,800
|
|
| G
|
Pex13
|
peroxisomal biogenesis factor 13
|
multiple interactions
|
ISO
|
MT1 affects the reaction [Nickel affects the expression of PEX13 mRNA]; MT2 affects the reaction [Nickel affects the expression of PEX13 mRNA]
|
CTD |
PMID:16166738 |
|
NCBI chr14:101,804,673...101,822,367
Ensembl chr14:101,804,673...101,822,367
|
|
| G
|
Pex16
|
peroxisomal biogenesis factor 16
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PEX16 mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr 3:98,800,357...98,808,091
Ensembl chr 3:98,798,654...98,808,630
|
|
| G
|
Pex6
|
peroxisomal biogenesis factor 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PEX6 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 9:21,755,747...21,767,939
Ensembl chr 9:21,755,751...21,767,908
|
|
| G
|
Pf4
|
platelet factor 4
|
multiple interactions
|
ISO
|
[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PF4 mRNA; TNF protein inhibits the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PF4 mRNA]
|
CTD |
PMID:23503329 |
|
NCBI chr14:17,582,477...17,583,392
Ensembl chr14:17,582,477...17,583,392
|
|
| G
|
Pfkfb3
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
|
increases expression
|
ISO
|
Nickel results in increased expression of PFKFB3 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr17:71,893,320...71,974,526
Ensembl chr17:71,893,416...71,975,052
|
|
| G
|
Pfkp
|
phosphofructokinase, platelet
|
increases expression
|
ISO
|
Nickel results in increased expression of PFKP mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr17:68,639,749...68,704,055
Ensembl chr17:68,639,481...68,705,752
|
|
| G
|
Pfn2
|
profilin 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PFN2 mRNA
|
CTD |
PMID:18922574 |
|
NCBI chr 2:144,217,100...144,222,936
Ensembl chr 2:144,205,636...144,222,936
|
|
| G
|
Pgcka1
|
PDCD10 and GCKIII kinases associated 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PGCKA1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr14:44,740,965...44,832,180
Ensembl chr14:44,740,972...44,831,613
|
|
| G
|
Pgf
|
placental growth factor
|
increases expression
|
ISO
|
Nickel results in increased expression of PGF mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:110,547,165...110,557,747
Ensembl chr 6:110,547,153...110,557,747
|
|
| G
|
Pgghg
|
protein-glucosylgalactosylhydroxylysine glucosidase
|
increases expression
|
ISO
|
Nickel results in increased expression of PGGHG mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:205,467,179...205,474,185
Ensembl chr 1:205,467,993...205,474,183
|
|
| G
|
Pgk1
|
phosphoglycerate kinase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of PGK1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr X:75,336,988...75,352,962
Ensembl chr X:75,336,687...75,352,959
|
|
| G
|
Pglyrp2
|
peptidoglycan recognition protein 2
|
affects binding
|
ISO
|
PGLYRP2 protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr 7:12,069,414...12,082,437
Ensembl chr 7:12,069,414...12,078,369
|
|
| G
|
Pgm2
|
phosphoglucomutase 2
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of PGM2 mRNA Nickel results in increased expression of PGM2 mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr14:44,519,906...44,553,420
Ensembl chr14:44,519,906...44,553,770
|
|
| G
|
Pgm5
|
phosphoglucomutase 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PGM5 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:231,752,052...231,939,812
Ensembl chr 1:231,752,052...231,939,812
|
|
| G
|
Pgr
|
progesterone receptor
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PGR mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:14,354,398...14,413,271
|
|
| G
|
Phc3
|
polyhomeotic homolog 3
|
increases expression
|
ISO
|
Nickel results in increased expression of PHC3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:114,337,180...114,412,132
Ensembl chr 2:114,337,227...114,405,816
|
|
| G
|
Phf1
|
PHD finger protein 1
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of PHF1 mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr20:5,019,650...5,024,732
Ensembl chr20:5,019,673...5,024,731
|
|
| G
|
Phf11
|
PHD finger protein 11
|
increases expression
|
ISO
|
Nickel results in increased expression of PHF11 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr15:37,568,090...37,592,490
Ensembl chr15:37,568,090...37,591,016
|
|
| G
|
Phf12
|
PHD finger protein 12
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of PHF12 mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr10:63,368,547...63,417,079
Ensembl chr10:63,370,210...63,417,073
|
|
| G
|
Phf19
|
PHD finger protein 19
|
increases expression
|
ISO
|
Nickel results in increased expression of PHF19 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:38,572,766...38,604,950
Ensembl chr 3:38,572,766...38,593,854
|
|
| G
|
Phf23
|
PHD finger protein 23
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PHF23 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr10:55,217,351...55,221,471
Ensembl chr10:55,217,351...55,221,471
|
|
| G
|
Phf7
|
PHD finger protein 7
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PHF7 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr16:6,439,968...6,452,671
Ensembl chr16:6,439,970...6,452,671
|
|
| G
|
Phkb
|
phosphorylase kinase regulatory subunit beta
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PHKB mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr19:37,179,937...37,383,979
Ensembl chr19:37,186,042...37,383,877
|
|
| G
|
Phlda1
|
pleckstrin homology-like domain, family A, member 1
|
increases expression
|
ISO
|
Nickel results in increased expression of PHLDA1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 7:48,853,690...48,855,894
Ensembl chr 7:48,853,260...48,857,542
|
|
| G
|
Phldb1
|
pleckstrin homology-like domain, family B, member 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PHLDB1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:53,900,338...53,948,325
Ensembl chr 8:53,900,338...53,949,518
|
|
| G
|
Phospho2
|
phosphatase, orphan 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PHOSPHO2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:74,962,649...74,969,810
Ensembl chr 3:74,962,361...74,970,892
|
|
| G
|
Phyhd1
|
phytanoyl-CoA dioxygenase domain containing 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PHYHD1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:33,933,487...33,951,614
Ensembl chr 3:33,937,898...33,951,614
|
|
| G
|
Phyhip
|
phytanoyl-CoA 2-hydroxylase interacting protein
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PHYHIP mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr15:51,943,670...51,954,921
Ensembl chr15:51,943,378...51,954,920
|
|
| G
|
Pi15
|
peptidase inhibitor 15
|
increases expression
|
ISO
|
Nickel results in increased expression of PI15 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:6,178,427...6,206,548
Ensembl chr 5:6,174,963...6,247,841
|
|
| G
|
Pierce2
|
piercer of microtubule wall 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PIERCE2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:82,596,034...82,600,500
Ensembl chr 8:82,591,000...82,600,852
|
|
| G
|
Piezo1
|
piezo-type mechanosensitive ion channel component 1
|
increases expression
|
ISO
|
Nickel results in increased expression of PIEZO1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr19:67,453,120...67,515,347
Ensembl chr19:67,453,122...67,515,037
|
|
| G
|
Piezo2
|
piezo-type mechanosensitive ion channel component 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PIEZO2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr18:58,738,734...59,115,252
Ensembl chr18:58,738,740...59,115,215
|
|
| G
|
Piga
|
phosphatidylinositol glycan anchor biosynthesis, class A
|
increases expression
|
ISO
|
Nickel results in increased expression of PIGA mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr X:33,672,832...33,687,747
Ensembl chr X:33,674,923...33,687,636
|
|
| G
|
Pigm
|
phosphatidylinositol glycan anchor biosynthesis, class M
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of PIGM mRNA Nickel results in increased expression of PIGM mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr13:87,370,693...87,374,390
Ensembl chr13:87,368,359...87,376,206
|
|
| G
|
Pigw
|
phosphatidylinositol glycan anchor biosynthesis, class W
|
increases expression
|
ISO
|
Nickel results in increased expression of PIGW mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:70,246,904...70,248,412
Ensembl chr10:70,243,810...70,250,329
|
|
| G
|
Pigz
|
phosphatidylinositol glycan anchor biosynthesis, class Z
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PIGZ mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:82,336,821...82,357,743
Ensembl chr11:82,336,823...82,340,684
|
|
| G
|
Pik3c2g
|
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PIK3C2G mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:174,215,527...174,583,378
Ensembl chr 4:174,215,527...174,581,705
|
|
| G
|
Pik3cd
|
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
|
increases expression
|
ISO
|
Nickel results in increased expression of PIK3CD mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:165,377,994...165,426,620
Ensembl chr 5:165,377,994...165,403,968
|
|
| G
|
Pik3cg
|
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
|
increases expression
|
ISO
|
Nickel results in increased expression of PIK3CG mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 6:54,494,247...54,529,563
Ensembl chr 6:54,478,603...54,529,509
|
|
| G
|
Pik3r1
|
phosphoinositide-3-kinase regulatory subunit 1
|
multiple interactions
|
ISO
|
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Melatonin inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in decreased expression of PIK3R1 mRNA]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [[nickel chloride results in increased abundance of Nickel] which results in decreased expression of PIK3R1 mRNA]; [nickel chloride results in increased abundance of Nickel] which results in decreased expression of PIK3R1 mRNA; Melatonin inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in decreased expression of PIK3R1 mRNA]
|
CTD |
PMID:35568058 |
|
NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:34,612,946...34,626,347
|
|
| G
|
Pik3r4
|
phosphoinositide-3-kinase, regulatory subunit 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PIK3R4 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 8:115,146,660...115,195,326
Ensembl chr 8:115,146,687...115,195,326
|
|
| G
|
Pik3r5
|
phosphoinositide-3-kinase, regulatory subunit 5
|
increases expression
|
ISO
|
Nickel results in increased expression of PIK3R5 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:53,631,469...53,699,550
Ensembl chr10:53,631,476...53,699,539
|
|
| G
|
Pim1
|
Pim-1 proto-oncogene, serine/threonine kinase
|
increases expression
|
ISO
|
Nickel results in increased expression of PIM1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr20:7,556,496...7,560,747
Ensembl chr20:7,556,113...7,561,764
|
|
| G
|
Pim2
|
Pim-2 proto-oncogene, serine/threonine kinase
|
increases expression
|
ISO
|
Nickel results in increased expression of PIM2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:17,289,509...17,294,778
Ensembl chr X:17,289,509...17,294,778
|
|
| G
|
Pim3
|
Pim-3 proto-oncogene, serine/threonine kinase
|
increases expression
|
ISO
|
Nickel results in increased expression of PIM3 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 7:121,822,076...121,836,257
Ensembl chr 7:121,832,742...121,836,259
|
|
| G
|
Pink1
|
PTEN induced kinase 1
|
multiple interactions
|
ISO
|
[nickel chloride results in increased abundance of Nickel] which affects the expression of and affects the localization of PINK1 protein
|
CTD |
PMID:36794572 |
|
NCBI chr 5:155,813,838...155,825,950
Ensembl chr 5:155,813,838...155,825,950
|
|
| G
|
Pip
|
prolactin induced protein
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PIP mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:71,754,265...71,758,559
Ensembl chr 4:71,754,265...71,758,559
|
|
| G
|
Pip4k2a
|
phosphatidylinositol-5-phosphate 4-kinase type 2 alpha
|
increases expression
|
ISO
|
Nickel results in increased expression of PIP4K2A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr17:86,405,080...86,576,597
Ensembl chr17:86,405,081...86,576,430
|
|
| G
|
Pip5k1b
|
phosphatidylinositol-4-phosphate 5-kinase type 1 beta
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PIP5K1B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:231,331,836...231,610,092
Ensembl chr 1:231,340,606...231,496,812
|
|
| G
|
Pirb
|
paired Ig-like receptor B
|
increases expression
|
ISO
|
Nickel results in increased expression of LILRB3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:74,414,556...74,433,015
Ensembl chr 1:74,331,291...74,422,116
|
|
| G
|
Pitpnc1
|
phosphatidylinositol transfer protein, cytoplasmic 1
|
increases expression
|
ISO
|
Nickel results in increased expression of PITPNC1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr10:92,663,260...92,928,616
Ensembl chr10:92,663,260...92,928,344
|
|
| G
|
Pitpnm3
|
PITPNM family member 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PITPNM3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:57,173,230...57,265,186
Ensembl chr10:57,175,721...57,265,291
|
|
| G
|
Pitx2
|
paired-like homeodomain 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PITX2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:220,391,417...220,411,588
Ensembl chr 2:220,391,888...220,411,591
|
|
| G
|
Pjvk
|
pejvakin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PJVK mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:82,002,106...82,012,273
Ensembl chr 3:82,002,368...82,012,451
|
|
| G
|
Pklr
|
pyruvate kinase L/R
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PKLR mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 2:176,840,779...176,849,637
Ensembl chr 2:176,840,764...176,849,644
|
|
| G
|
Pknox2
|
PBX/knotted 1 homeobox 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PKNOX2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:44,789,464...45,051,933
Ensembl chr 8:44,789,467...44,979,754
|
|
| G
|
Pla1a
|
phospholipase A1 member A
|
increases expression
|
ISO
|
Nickel results in increased expression of PLA1A mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr11:75,825,626...75,863,296
Ensembl chr11:75,825,585...75,878,165
|
|
| G
|
Pla2g2a
|
phospholipase A2 group IIA
|
increases expression
|
ISO
|
Nickel results in increased expression of PLA2G2A mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:156,359,725...156,362,302
Ensembl chr 5:156,359,725...156,362,297
|
|
| G
|
Pla2g3
|
phospholipase A2, group III
|
increases expression
|
ISO
|
Nickel results in increased expression of PLA2G3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:82,589,908...82,597,542
Ensembl chr14:82,591,862...82,597,542
|
|
| G
|
Pla2g4c
|
phospholipase A2 group IVC
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PLA2G4C mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:83,315,017...83,411,342
Ensembl chr 1:83,382,068...83,410,037
|
|
| G
|
Pla2g7
|
phospholipase A2 group VII
|
increases expression decreases expression
|
ISO
|
Nickel results in increased expression of PLA2G7 mRNA Nickel results in decreased expression of PLA2G7 mRNA
|
CTD |
PMID:12540486 PMID:24768652 |
|
NCBI chr 9:24,859,491...24,901,747
Ensembl chr 9:24,859,502...24,901,747
|
|
| G
|
Pla2r1
|
phospholipase A2 receptor 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PLA2R1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:65,292,629...65,422,462
Ensembl chr 3:65,292,629...65,422,335
|
|
| G
|
Plaat3
|
phospholipase A and acyltransferase 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PLAAT3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:214,211,755...214,245,551
Ensembl chr 1:214,211,791...214,246,763
|
|
| G
|
Plaat5
|
phospholipase A and acyltransferase 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PLAAT5 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:214,276,553...214,307,600
Ensembl chr 1:214,277,044...214,307,598
|
|
| G
|
Plac8
|
placenta associated 8
|
increases expression
|
ISO
|
Nickel results in increased expression of PLAC8 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr14:9,356,950...9,378,586
Ensembl chr14:9,356,972...9,378,572
|
|
| G
|
Plag1
|
PLAG1 zinc finger
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PLAG1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:21,699,650...21,754,325
Ensembl chr 5:21,702,987...21,711,240
|
|
| G
|
Plagl2
|
PLAG1 like zinc finger 2
|
increases expression
|
ISO
|
Nickel results in increased expression of PLAGL2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:162,155,554...162,168,748
Ensembl chr 3:162,155,554...162,168,748
|
|
| G
|
Plau
|
plasminogen activator, urokinase
|
increases expression
|
ISO
|
Nickel results in increased expression of PLAU mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,505,487...3,512,030
|
|
| G
|
Plaur
|
plasminogen activator, urokinase receptor
|
increases expression
|
ISO
|
Nickel results in increased expression of PLAUR mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:89,181,363...89,196,308
Ensembl chr 1:89,178,453...89,198,130
|
|
| G
|
Plcb1
|
phospholipase C beta 1
|
increases expression decreases expression
|
ISO
|
Nickel results in increased expression of PLCB1 mRNA Nickel results in decreased expression of PLCB1 mRNA
|
CTD |
PMID:18922574 PMID:25583101 |
|
NCBI chr 3:142,512,765...143,224,042
Ensembl chr 3:142,513,033...143,225,646
|
|
| G
|
Plcb4
|
phospholipase C, beta 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PLCB4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:143,405,721...143,775,129
Ensembl chr 3:143,405,950...143,775,113
|
|
| G
|
Plce1
|
phospholipase C, epsilon 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PLCE1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:245,655,855...245,964,966
Ensembl chr 1:245,657,080...245,963,828
|
|
| G
|
Plcl2
|
phospholipase C-like 2
|
increases expression
|
ISO
|
Nickel results in increased expression of PLCL2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 9:3,529,117...3,713,712
Ensembl chr 9:3,529,841...3,713,712
|
|
| G
|
Plcxd2
|
phosphatidylinositol-specific phospholipase C, X domain containing 2
|
increases expression
|
ISO
|
Nickel results in increased expression of PLCXD2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr11:68,263,626...68,315,962
Ensembl chr11:68,263,566...68,316,327
|
|
| G
|
Plcxd3
|
phosphatidylinositol-specific phospholipase C, X domain containing 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PLCXD3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:55,294,597...55,473,968
Ensembl chr 2:55,294,613...55,474,220
|
|
| G
|
Plek
|
pleckstrin
|
increases expression
|
ISO
|
Nickel results in increased expression of PLEK mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr14:95,598,650...95,631,326
Ensembl chr14:95,598,654...95,655,721
|
|
| G
|
Plek2
|
pleckstrin 2
|
increases expression
|
ISO
|
Nickel results in increased expression of PLEK2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 6:103,434,156...103,452,457
Ensembl chr 6:103,434,156...103,452,371
|
|
| G
|
Plekha4
|
pleckstrin homology domain containing A4
|
increases expression
|
ISO
|
Nickel results in increased expression of PLEKHA4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:105,142,296...105,165,297
Ensembl chr 1:105,142,348...105,165,297
|
|
| G
|
Plekha6
|
pleckstrin homology domain containing A6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PLEKHA6 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:47,166,899...47,307,003
Ensembl chr13:47,167,160...47,307,003
|
|
| G
|
Plekhb1
|
pleckstrin homology domain containing B1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PLEKHB1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:164,410,901...164,425,216
Ensembl chr 1:164,410,903...164,428,568
|
|
| G
|
Plekhh1
|
pleckstrin homology, MyTH4 and FERM domain containing H1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PLEKHH1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:103,572,304...103,621,729
Ensembl chr 6:103,572,291...103,621,728
|
|
| G
|
Plekhh2
|
pleckstrin homology, MyTH4 and FERM domain containing H2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PLEKHH2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 6:15,783,179...15,893,479
Ensembl chr 6:15,784,645...15,893,537
|
|
| G
|
Plekho1
|
pleckstrin homology domain containing O1
|
increases expression
|
ISO
|
Nickel results in increased expression of PLEKHO1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:186,233,435...186,242,114
Ensembl chr 2:186,233,452...186,241,354
|
|
| G
|
Plekho2
|
pleckstrin homology domain containing O2
|
increases expression
|
ISO
|
Nickel results in increased expression of PLEKHO2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:74,973,578...75,000,532
Ensembl chr 8:74,974,740...75,000,430
|
|
| G
|
Plg
|
plasminogen
|
affects binding decreases expression
|
ISO
|
PLG protein binds to Nickel Nickel analog results in decreased expression of PLG protein alternative form
|
CTD |
PMID:23896426 PMID:25144474 |
|
NCBI chr 1:50,872,927...50,915,406
Ensembl chr 1:50,872,926...50,917,320
|
|
| G
|
Plin4
|
perilipin 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PLIN4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 9:1,016,334...1,025,249
Ensembl chr 9:1,016,302...1,025,368
|
|
| G
|
Plin5
|
perilipin 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PLIN5 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 9:1,026,910...1,033,352
Ensembl chr 9:1,026,307...1,033,284
|
|
| G
|
Plk1
|
polo-like kinase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of PLK1 mRNA
|
CTD |
PMID:19031421 |
|
NCBI chr 1:186,147,658...186,157,637
Ensembl chr 1:186,147,658...186,157,637
|
|
| G
|
Plk3
|
polo-like kinase 3
|
increases expression
|
ISO
|
Nickel results in increased expression of PLK3 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 5:135,843,725...135,848,900
Ensembl chr 5:135,843,725...135,848,900
|
|
| G
|
Pllp
|
plasmolipin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PLLP mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr19:10,321,080...10,341,869
Ensembl chr19:10,321,080...10,342,226
|
|
| G
|
Pln
|
phospholamban
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PLN mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr20:33,166,512...33,182,241
Ensembl chr20:33,172,494...33,182,241
|
|
| G
|
Plod2
|
procollagen lysine, 2-oxoglutarate 5-dioxygenase 2
|
increases expression
|
ISO
|
Nickel results in increased expression of PLOD2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 8:101,964,318...102,047,022
Ensembl chr 8:101,964,318...102,047,022
|
|
| G
|
Plp1
|
proteolipid protein 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PLP1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr X:104,933,921...104,993,317
Ensembl chr X:104,975,780...104,993,314
|
|
| G
|
Plpp4
|
phospholipid phosphatase 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PLPP4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:193,260,181...193,389,659
Ensembl chr 1:193,260,434...193,389,675
|
|
| G
|
Plscr1
|
phospholipid scramblase 1
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of PLSCR1 mRNA Nickel results in increased expression of PLSCR1 mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 8:101,662,512...101,684,474
Ensembl chr 8:101,664,056...101,684,614
|
|
| G
|
Plxnb2
|
plexin B2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PLXNB2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 7:122,111,917...122,138,201
Ensembl chr 7:122,111,917...122,127,746
|
|
| G
|
Pmaip1
|
phorbol-12-myristate-13-acetate-induced protein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of PMAIP1 mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr18:62,255,970...62,262,384
Ensembl chr18:62,255,598...62,262,382
|
|
| G
|
Pmch
|
pro-melanin-concentrating hormone
|
increases expression
|
ISO
|
Nickel results in increased expression of PMCH mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:24,399,404...24,400,720
Ensembl chr 7:24,399,404...24,400,720
|
|
| G
|
Pml
|
PML nuclear body scaffold
|
increases expression
|
ISO
|
Nickel results in increased expression of PML mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:67,523,164...67,557,801
Ensembl chr 8:67,523,164...67,576,083
|
|
| G
|
Pmm2
|
phosphomannomutase 2
|
increases expression
|
ISO
|
Nickel results in increased expression of PMM2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:7,468,371...7,489,574
Ensembl chr10:7,468,372...7,489,554
|
|
| G
|
Pnkd
|
PNKD metallo-beta-lactamase domain containing
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PNKD mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:83,317,757...83,386,263
Ensembl chr 9:83,317,738...83,386,262
|
|
| G
|
Pnldc1
|
PARN like ribonuclease domain containing exonuclease 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PNLDC1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 1:50,390,884...50,409,457
Ensembl chr 1:50,390,918...50,409,457
|
|
| G
|
Pnma8a
|
PNMA family member 8A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PNMA8A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:86,763,475...86,771,117
Ensembl chr 1:86,756,168...86,815,182
|
|
| G
|
Pno1
|
partner of NOB1 homolog
|
increases expression
|
ISO
|
Nickel results in increased expression of PNO1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr14:95,811,335...95,819,903
Ensembl chr14:95,688,125...95,905,881
|
|
| G
|
Pnp
|
purine nucleoside phosphorylase
|
increases expression
|
ISO
|
Nickel results in increased expression of PNP mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr15:26,644,147...26,651,808
Ensembl chr15:26,643,858...26,678,162
|
|
| G
|
Pnpla3
|
patatin-like phospholipase domain containing 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PNPLA3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:117,173,485...117,194,065
Ensembl chr 7:117,173,516...117,194,594
|
|
| G
|
Pnpla6
|
patatin-like phospholipase domain containing 6
|
increases expression
|
ISO
|
Nickel results in increased expression of PNPLA6 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr12:6,372,284...6,401,632
Ensembl chr12:6,372,293...6,401,631
|
|
| G
|
Pnpla7
|
patatin-like phospholipase domain containing 7
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PNPLA7 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:28,180,670...28,259,673
Ensembl chr 3:28,180,751...28,259,672
|
|
| G
|
Pnpt1
|
polyribonucleotide nucleotidyltransferase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of PNPT1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr14:107,078,486...107,109,628
Ensembl chr14:107,078,469...107,109,628
|
|
| G
|
Podn
|
podocan
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PODN mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:128,003,907...128,025,518
Ensembl chr 5:128,008,125...128,110,043
|
|
| G
|
Poglut1
|
protein O-glucosyltransferase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of POGLUT1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr11:75,704,119...75,731,964
Ensembl chr11:75,703,833...75,733,519
|
|
| G
|
Pola2
|
DNA polymerase alpha 2, accessory subunit
|
increases expression
|
ISO
|
Nickel results in increased expression of POLA2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:212,656,500...212,680,667
Ensembl chr 1:212,656,501...212,680,542
|
|
| G
|
Pole2
|
DNA polymerase epsilon 2, accessory subunit
|
increases expression
|
ISO
|
Nickel results in increased expression of POLE2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 6:93,410,713...93,448,782
Ensembl chr 6:93,410,758...93,435,361
|
|
| G
|
Polh
|
DNA polymerase eta
|
decreases expression
|
ISO
|
Nickel results in decreased expression of POLH mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 9:22,275,929...22,310,576
Ensembl chr 9:22,275,946...22,310,577
|
|
| G
|
Polk
|
DNA polymerase kappa
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of POLK mRNA trichostatin A inhibits the reaction [Nickel affects the expression of POLK mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 2:29,556,831...29,616,960
Ensembl chr 2:29,557,336...29,616,960
|
|
| G
|
Polr1b
|
RNA polymerase I subunit B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of POLR1B mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 3:136,787,130...136,811,608
Ensembl chr 3:136,787,107...136,811,607
|
|
| G
|
Polr1c
|
RNA polymerase I and III subunit C
|
increases expression
|
ISO
|
Nickel results in increased expression of POLR1C mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:22,233,318...22,237,430
Ensembl chr 9:22,233,305...22,237,428
|
|
| G
|
Polr1has
|
RNA polymerase I subunit H, antisense
|
decreases expression
|
ISO
|
Nickel results in decreased expression of POLR1HASP mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 9:23,596,073...23,597,239
Ensembl chr 9:23,596,073...23,597,239
|
|
| G
|
Polr2b
|
RNA polymerase II subunit B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of POLR2B mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr14:31,151,534...31,189,222
Ensembl chr14:31,151,390...31,189,222
|
|
| G
|
Polr2d
|
RNA polymerase II subunit D
|
increases expression
|
ISO
|
Nickel results in increased expression of POLR2D mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr18:23,692,578...23,699,709
Ensembl chr18:23,692,578...23,699,709
|
|
| G
|
Polr3e
|
RNA polymerase III subunit E
|
multiple interactions
|
EXP
|
[Tungsten co-treated with Nickel co-treated with Cobalt] results in increased expression of POLR3E mRNA; [Tungsten co-treated with Nickel co-treated with Iron] results in increased expression of POLR3E mRNA
|
CTD |
PMID:24619124 |
|
NCBI chr 1:184,897,383...184,925,547
Ensembl chr 1:184,897,426...184,926,534
|
|
| G
|
Polr3g
|
RNA polymerase III subunit G
|
increases expression
|
ISO
|
Nickel results in increased expression of POLR3G mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:13,680,893...13,721,802
Ensembl chr 2:13,680,895...13,721,802
|
|
| G
|
Pomc
|
proopiomelanocortin
|
increases expression
|
EXP
|
Nickel results in increased expression of POMC mRNA
|
CTD |
PMID:20682304 |
|
NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:32,659,346...32,665,173
|
|
| G
|
Pon1
|
paraoxonase 1
|
decreases expression affects binding
|
ISO
|
Nickel results in decreased expression of PON1 mRNA PON1 protein binds to Nickel
|
CTD |
PMID:12540486 PMID:23896426 |
|
NCBI chr 4:34,261,312...34,292,327
Ensembl chr 4:34,261,289...34,287,924
|
|
| G
|
Pon3
|
paraoxonase 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PON3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:34,323,546...34,350,244
Ensembl chr 4:34,315,889...34,350,244
|
|
| G
|
Pop1
|
POP1 homolog, ribonuclease P/MRP subunit
|
increases expression
|
ISO
|
Nickel results in increased expression of POP1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:67,590,502...67,618,187
Ensembl chr 7:67,590,522...67,618,293
|
|
| G
|
Postn
|
periostin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of POSTN mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:140,677,774...140,709,304
Ensembl chr 2:140,677,754...140,709,300
|
|
| G
|
Pou2af1
|
POU class 2 homeobox associating factor 1
|
increases expression
|
ISO
|
Nickel results in increased expression of POU2AF1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:60,418,173...60,445,176
Ensembl chr 8:60,436,844...60,445,176
|
|
| G
|
Pou2af3
|
POU class 2 homeobox associating factor 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of POU2AF3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:60,484,596...60,493,475
Ensembl chr 8:60,484,596...60,493,821
|
|
| G
|
Pou2f2
|
POU class 2 homeobox 2
|
increases expression
|
ISO
|
Nickel results in increased expression of POU2F2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:89,810,153...89,897,560
Ensembl chr 1:89,812,093...89,897,564
|
|
| G
|
Pou2f3
|
POU class 2 homeobox 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of POU2F3 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 8:52,392,363...52,474,756
Ensembl chr 8:52,392,497...52,474,756
|
|
| G
|
Ppan
|
peter pan homolog
|
increases expression
|
ISO
|
Nickel results in increased expression of PPAN mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:27,700,147...27,704,127
Ensembl chr 8:27,700,152...27,704,128
|
|
| G
|
Pparg
|
peroxisome proliferator-activated receptor gamma
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PPARG mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
|
|
| G
|
Ppargc1a
|
PPARG coactivator 1 alpha
|
decreases expression multiple interactions
|
ISO
|
Nickel results in decreased expression of PPARGC1A mRNA [nickel chloride results in increased abundance of Nickel] which results in decreased expression of PPARGC1A mRNA; [nickel chloride results in increased abundance of Nickel] which results in decreased expression of PPARGC1A protein
|
CTD |
PMID:24768652 PMID:25583101 PMID:36794572 |
|
NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213
|
|
| G
|
Ppbp
|
pro-platelet basic protein
|
increases expression affects binding multiple interactions
|
ISO
|
Nickel results in increased expression of PPBP mRNA PPBP protein binds to Nickel Nickel results in increased expression of and results in increased secretion of PPBP protein
|
CTD |
PMID:23624239 PMID:23896426 |
|
NCBI chr14:17,586,495...17,587,299
Ensembl chr14:17,586,495...17,587,299
|
|
| G
|
Ppfia4
|
PTPRF interacting protein alpha 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PPFIA4 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr13:48,305,844...48,354,329
Ensembl chr13:48,305,848...48,354,279
|
|
| G
|
Ppfibp1
|
PPFIA binding protein 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PPFIBP1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:181,538,249...181,682,079
Ensembl chr 4:181,539,450...181,682,076
|
|
| G
|
Pphln1
|
periphilin 1
|
increases expression
|
ISO
|
Nickel results in increased expression of PPHLN1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:126,418,042...126,509,430
Ensembl chr 7:126,417,555...126,509,430
|
|
| G
|
Ppib
|
peptidylprolyl isomerase B
|
increases expression
|
ISO
|
Nickel results in increased expression of PPIB mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:75,498,966...75,504,823
Ensembl chr 8:75,498,797...75,504,847
|
|
| G
|
Ppm1a
|
protein phosphatase, Mg2+/Mn2+ dependent, 1A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PPM1A mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 6:97,174,955...97,216,585
Ensembl chr 6:97,174,916...97,216,574
|
|
| G
|
Ppm1h
|
protein phosphatase, Mg2+/Mn2+ dependent, 1H
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PPM1H mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:60,224,087...60,484,947
Ensembl chr 7:60,223,745...60,488,140
|
|
| G
|
Ppm1l
|
protein phosphatase, Mg2+/Mn2+ dependent, 1L
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PPM1L mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:155,876,605...156,149,371
Ensembl chr 2:155,876,605...156,149,371
|
|
| G
|
Ppp1r10
|
protein phosphatase 1, regulatory subunit 10
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of PPP1R10 mRNA Nickel results in increased expression of PPP1R10 mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr20:2,827,802...2,842,418
Ensembl chr20:2,827,802...2,842,418
|
|
| G
|
Ppp1r12a
|
protein phosphatase 1, regulatory subunit 12A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PPP1R12A mRNA
|
CTD |
PMID:18922574 |
|
NCBI chr 7:45,368,922...45,480,158
Ensembl chr 7:45,369,315...45,480,157
|
|
| G
|
Ppp1r12b
|
protein phosphatase 1, regulatory subunit 12B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PPP1R12B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:48,751,256...48,948,933
Ensembl chr13:48,751,477...48,948,922
|
|
| G
|
Ppp1r14a
|
protein phosphatase 1, regulatory (inhibitor) subunit 14A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PPP1R14A mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:93,708,269...93,718,218
Ensembl chr 1:93,708,218...93,719,147
|
|
| G
|
Ppp1r16b
|
protein phosphatase 1, regulatory subunit 16B
|
increases expression
|
ISO
|
Nickel results in increased expression of PPP1R16B mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:167,743,518...167,839,511
Ensembl chr 3:167,743,952...167,839,242
|
|
| G
|
Ppp1r18
|
protein phosphatase 1, regulatory subunit 18
|
increases expression
|
ISO
|
Nickel results in increased expression of PPP1R18 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr20:2,882,370...2,892,329
Ensembl chr20:2,882,369...2,896,605
|
|
| G
|
Ppp1r1a
|
protein phosphatase 1, regulatory (inhibitor) subunit 1A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PPP1R1A mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:136,533,031...136,540,687
Ensembl chr 7:136,523,604...136,540,683
|
|
| G
|
Ppp1r1b
|
protein phosphatase 1, regulatory (inhibitor) subunit 1B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PPP1R1B mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:83,843,948...83,853,063
Ensembl chr10:83,844,036...83,853,063
|
|
| G
|
Ppp1r2
|
protein phosphatase 1, regulatory (inhibitor) subunit 2
|
increases expression
|
ISO
|
Nickel results in increased expression of PPP1R2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:82,977,634...82,999,426
Ensembl chr11:82,977,515...83,001,083
|
|
| G
|
Ppp1r21
|
protein phosphatase 1, regulatory subunit 21
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PPP1R21 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 6:11,655,059...11,724,219
Ensembl chr 6:11,655,059...11,724,219
|
|
| G
|
Ppp1r36
|
protein phosphatase 1, regulatory subunit 36
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PPP1R36 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 6:100,874,397...100,894,764
Ensembl chr 6:100,874,374...100,894,756
|
|
| G
|
Ppp1r3c
|
protein phosphatase 1, regulatory subunit 3C
|
increases expression
|
ISO
|
Nickel results in increased expression of PPP1R3C mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:243,873,524...243,878,527
Ensembl chr 1:243,871,704...243,878,835
|
|
| G
|
Ppp1r9a
|
protein phosphatase 1, regulatory subunit 9A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PPP1R9A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:33,936,949...34,258,927
Ensembl chr 4:33,988,827...34,258,927
|
|
| G
|
Ppp1r9b
|
protein phosphatase 1, regulatory subunit 9B
|
increases expression
|
ISO
|
Nickel results in increased expression of PPP1R9B mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:80,434,888...80,450,919
Ensembl chr10:80,434,900...80,450,919
|
|
| G
|
Ppp2cb
|
protein phosphatase 2 catalytic subunit beta
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PPP2CB mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr16:65,261,178...65,282,658
Ensembl chr16:65,261,181...65,282,634
|
|
| G
|
Ppp2r2c
|
protein phosphatase 2, regulatory subunit B, gamma
|
increases expression
|
ISO
|
Nickel results in increased expression of PPP2R2C mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr14:78,071,274...78,156,212
Ensembl chr14:78,071,274...78,156,212
|
|
| G
|
Ppp3r1
|
protein phosphatase 3, regulatory subunit B, alpha
|
increases expression
|
ISO
|
Nickel results in increased expression of PPP3R1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:95,758,333...95,808,015
|
|
| G
|
Ppp4c
|
protein phosphatase 4, catalytic subunit
|
increases expression
|
ISO
|
Nickel results in increased expression of PPP4C mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:190,823,447...190,830,247
Ensembl chr 1:190,823,486...190,830,168
|
|
| G
|
Ppp6r1
|
protein phosphatase 6, regulatory subunit 1
|
increases expression
|
ISO
|
Nickel results in increased expression of PPP6R1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:78,218,629...78,246,360
Ensembl chr 1:78,219,154...78,246,350
|
|
| G
|
Pprc1
|
PPARG related coactivator 1
|
increases expression
|
ISO
|
Nickel results in increased expression of PPRC1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:254,851,136...254,867,570
Ensembl chr 1:254,851,164...254,867,570
|
|
| G
|
Prc1
|
protein regulator of cytokinesis 1
|
increases expression
|
ISO
|
Nickel results in increased expression of PRC1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 1:143,659,312...143,681,019
Ensembl chr 1:143,659,481...143,681,012
|
|
| G
|
Prcd
|
photoreceptor disc component
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PRCD mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:102,386,025...102,406,485
Ensembl chr10:102,385,826...102,390,987
|
|
| G
|
Prdm1
|
PR/SET domain 1
|
increases expression
|
ISO
|
Nickel results in increased expression of PRDM1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr20:49,542,465...49,564,088
Ensembl chr20:49,542,465...49,564,088
|
|
| G
|
Prdm16
|
PR/SET domain 16
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PRDM16 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:170,162,275...170,486,371
Ensembl chr 5:170,162,275...170,485,804
|
|
| G
|
Prdx1
|
peroxiredoxin 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PRDX1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 5:135,383,906...135,399,504
Ensembl chr 5:135,383,906...135,399,504
|
|
| G
|
Prdx3
|
peroxiredoxin 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PRDX3 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 1:269,987,691...270,000,111
Ensembl chr 1:269,987,685...270,000,300
|
|
| G
|
Prelid1
|
PRELI domain containing 1
|
increases expression
|
ISO
|
Nickel results in increased expression of PRELID1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr17:9,310,471...9,313,511
Ensembl chr17:9,310,472...9,313,531
|
|
| G
|
Prelp
|
proline and arginine rich end leucine rich repeat protein
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PRELP mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:47,920,480...47,943,547
Ensembl chr13:47,922,590...47,932,324
|
|
| G
|
Prep
|
prolyl endopeptidase
|
increases expression
|
ISO
|
Nickel results in increased expression of PREP mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr20:50,138,588...50,235,549
Ensembl chr20:50,131,819...50,252,697
|
|
| G
|
Prepl
|
prolyl endopeptidase-like
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PREPL mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 6:15,333,107...15,362,825
Ensembl chr 6:15,333,077...15,363,231
|
|
| G
|
Prex1
|
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
|
increases expression
|
ISO
|
Nickel results in increased expression of PREX1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:175,724,939...175,875,764
Ensembl chr 3:175,726,012...175,875,764
|
|
| G
|
Prf1
|
perforin 1
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of PRF1 mRNA Nickel results in increased expression of PRF1 mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr20:29,789,040...29,794,550
Ensembl chr20:29,788,972...29,795,124
|
|
| G
|
Prickle1
|
prickle planar cell polarity protein 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PRICKLE1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:126,518,587...126,614,581
Ensembl chr 7:126,518,587...126,614,581
|
|
| G
|
Prim1
|
DNA primase subunit 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PRIM1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 7:1,031,436...1,047,134
|
|
| G
|
Prima1
|
proline rich membrane anchor 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PRIMA1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:128,094,686...128,155,592
Ensembl chr 6:128,103,175...128,154,865
|
|
| G
|
Prkaa1
|
protein kinase AMP-activated catalytic subunit alpha 1
|
increases expression
|
ISO
|
Nickel results in increased expression of PRKAA1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:55,967,766...56,003,450
Ensembl chr 2:55,967,351...56,003,450
|
|
| G
|
Prkaa2
|
protein kinase AMP-activated catalytic subunit alpha 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PRKAA2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:125,036,945...125,109,010
Ensembl chr 5:125,042,179...125,108,324
|
|
| G
|
Prkab2
|
protein kinase AMP-activated non-catalytic subunit beta 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PRKAB2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:187,946,008...187,961,615
Ensembl chr 2:187,945,982...187,961,608
|
|
| G
|
Prkca
|
protein kinase C, alpha
|
increases expression
|
ISO
|
Nickel results in increased expression of PRKCA mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:93,388,991...93,787,617
Ensembl chr10:93,388,991...93,787,572
|
|
| G
|
Prkcb
|
protein kinase C, beta
|
increases expression
|
ISO
|
Nickel results in increased expression of PRKCB mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:186,263,397...186,594,743
Ensembl chr 1:186,263,447...186,594,740
|
|
| G
|
Prkcq
|
protein kinase C, theta
|
increases expression
|
ISO
|
Nickel results in increased expression of PRKCQ mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr17:72,156,215...72,288,508
Ensembl chr17:72,156,215...72,288,508
|
|
| G
|
Prkcz
|
protein kinase C, zeta
|
increases expression multiple interactions
|
ISO
|
Nickel results in increased expression of PRKCZ mRNA trichostatin A inhibits the reaction [Nickel affects the expression of PRKCZ mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 5:171,101,774...171,212,694
Ensembl chr 5:171,101,774...171,212,674
|
|
| G
|
Prkdc
|
protein kinase, DNA-activated, catalytic subunit
|
increases expression
|
ISO
|
Nickel results in increased expression of PRKDC mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:98,544,952...98,762,499
Ensembl chr11:98,544,954...98,762,108
|
|
| G
|
Prkg1
|
protein kinase cGMP-dependent 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PRKG1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:237,818,950...239,052,184
Ensembl chr 1:237,823,053...239,103,005
|
|
| G
|
Prkn
|
parkin RBR E3 ubiquitin protein ligase
|
multiple interactions
|
ISO
|
[nickel chloride results in increased abundance of Nickel] which affects the expression of and affects the localization of PRKN protein
|
CTD |
PMID:36794572 |
|
NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:51,210,330...52,430,304
|
|
| G
|
Prkx
|
protein kinase cAMP-dependent X-linked catalytic subunit
|
increases expression
|
ISO
|
Nickel results in increased expression of PRKX mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:45,701,747...45,745,210
Ensembl chr X:45,701,747...45,745,066
|
|
| G
|
Prlr
|
prolactin receptor
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PRLR mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:60,861,391...61,051,883
Ensembl chr 2:60,861,658...61,051,882
|
|
| G
|
Prmt5
|
protein arginine methyltransferase 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PRMT5 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr15:31,938,927...31,948,318
Ensembl chr15:31,938,719...31,948,426
|
|
| G
|
Prnd
|
prion like protein doppel
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PRND mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:139,666,383...139,671,647
Ensembl chr 3:139,666,068...139,671,890
|
|
| G
|
Prnp
|
prion protein
|
affects binding multiple interactions
|
ISO
|
Nickel binds to PRNP protein Nickel inhibits the reaction [PRNP protein binds to PRNP protein]
|
CTD |
PMID:16595185 PMID:17126907 |
|
NCBI chr 3:139,639,076...139,654,420
Ensembl chr 3:139,630,144...139,658,436
|
|
| G
|
Procr
|
protein C receptor
|
increases expression
|
ISO
|
Nickel results in increased expression of PROCR mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:164,714,727...164,718,994
Ensembl chr 3:164,711,636...164,718,989
|
|
| G
|
Pros1
|
protein S
|
affects binding
|
ISO
|
PROS1 protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr11:13,676,310...13,757,858
Ensembl chr11:13,676,769...13,757,852
|
|
| G
|
Prpf39
|
pre-mRNA processing factor 39
|
multiple interactions affects expression
|
ISO
|
trichostatin A inhibits the reaction [Nickel affects the expression of PRPF39 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 6:88,825,227...88,851,342
Ensembl chr 6:88,825,243...88,851,341
|
|
| G
|
Prps2
|
phosphoribosyl pyrophosphate synthetase 2
|
increases expression
|
ISO
|
Nickel results in increased expression of PRPS2 mRNA
|
CTD |
PMID:18922574 |
|
NCBI chr X:30,592,845...30,630,127
Ensembl chr X:30,593,019...30,630,126
|
|
| G
|
Prpsap1
|
phosphoribosyl pyrophosphate synthetase-associated protein 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PRPSAP1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:102,199,949...102,221,642
Ensembl chr10:102,199,950...102,221,642
|
|
| G
|
Prr15l
|
proline rich 15-like
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PRR15L mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:82,412,934...82,418,897
Ensembl chr10:82,402,733...82,419,558
|
|
| G
|
Prr16
|
proline rich 16
|
increases expression
|
ISO
|
Nickel results in increased expression of PRR16 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr18:46,622,816...46,963,251
Ensembl chr18:46,623,058...46,830,385
|
|
| G
|
Prr5l
|
proline rich 5 like
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PRR5L mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 3:108,458,107...108,628,552
Ensembl chr 3:108,458,633...108,537,763
|
|
| G
|
Prrg3
|
proline rich and Gla domain 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PRRG3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr X:154,711,246...154,731,359
Ensembl chr X:154,712,625...154,722,831
|
|
| G
|
Prrg4
|
proline rich and Gla domain 4
|
increases expression
|
ISO
|
Nickel results in increased expression of PRRG4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:111,669,508...111,698,205
Ensembl chr 3:111,673,582...111,698,205
|
|
| G
|
Prss12
|
serine protease 12
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PRSS12 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:214,308,695...214,368,679
Ensembl chr 2:214,308,774...214,369,941
|
|
| G
|
Prss23
|
serine protease 23
|
increases expression
|
ISO
|
Nickel results in increased expression of PRSS23 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:152,815,301...152,835,005
Ensembl chr 1:152,813,670...152,947,871
|
|
| G
|
Prss3
|
serine protease 3
|
increases expression
|
ISO
|
Nickel results in increased expression of PRSS3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:71,169,749...71,173,223
Ensembl chr 4:71,169,749...71,173,223
|
|
| G
|
Prss53
|
serine protease 53
|
increases expression
|
ISO
|
Nickel results in increased expression of PRSS53 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:191,923,398...191,931,292
Ensembl chr 1:191,925,434...191,955,449
|
|
| G
|
Prss8
|
serine protease 8
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PRSS8 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 1:191,966,701...191,971,271
Ensembl chr 1:191,966,701...191,971,193
|
|
| G
|
Prtfdc1
|
phosphoribosyl transferase domain containing 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PRTFDC1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr17:88,457,872...88,563,109
Ensembl chr17:88,457,872...88,563,066
|
|
| G
|
Prtg
|
protogenin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PRTG mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:82,429,106...82,538,612
Ensembl chr 8:82,429,132...82,538,602
|
|
| G
|
Prune2
|
prune homolog 2 with BCH domain
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PRUNE2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:223,779,617...224,130,058
Ensembl chr 1:223,969,102...224,051,592
|
|
| G
|
Prxl2a
|
peroxiredoxin like 2A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PRXL2A mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr16:16,900,697...16,920,521
Ensembl chr16:16,900,699...16,920,561
|
|
| G
|
Prxl2c
|
peroxiredoxin like 2C
|
increases expression
|
ISO
|
Nickel results in increased expression of PRXL2C mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr17:817,932...849,965
Ensembl chr17:817,949...840,940
|
|
| G
|
Psd3
|
pleckstrin and Sec7 domain containing 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PSD3 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr16:26,238,595...26,802,535
Ensembl chr16:26,340,028...26,802,535
|
|
| G
|
Psd4
|
pleckstrin and Sec7 domain containing 4
|
increases expression
|
ISO
|
Nickel results in increased expression of PSD4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:27,535,341...27,571,850
Ensembl chr 3:27,535,440...27,573,731
|
|
| G
|
Psen1
|
presenilin 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PSEN1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 6:109,054,160...109,106,191
Ensembl chr 6:109,060,352...109,106,189
|
|
| G
|
Psma3
|
proteasome 20S subunit alpha 3
|
increases expression
|
ISO
|
Nickel results in increased expression of PSMA3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 6:95,219,714...95,239,745
Ensembl chr 6:95,219,629...95,241,032
|
|
| G
|
Psma4
|
proteasome 20S subunit alpha 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PSMA4 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 8:64,236,520...64,243,980
Ensembl chr 8:64,236,783...64,243,979
|
|
| G
|
Psma5
|
proteasome 20S subunit alpha 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PSMA5 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 2:198,584,502...198,607,867
Ensembl chr 2:198,584,505...198,607,867
|
|
| G
|
Psmb10
|
proteasome 20S subunit beta 10
|
increases expression
|
ISO
|
Nickel results in increased expression of PSMB10 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr19:50,740,808...50,743,292
Ensembl chr19:50,740,811...50,743,210
|
|
| G
|
Psmb7
|
proteasome 20S subunit beta 7
|
multiple interactions
|
ISO
|
MT1 affects the reaction [Nickel affects the expression of PSMB7 mRNA]; MT2 affects the reaction [Nickel affects the expression of PSMB7 mRNA]
|
CTD |
PMID:16166738 |
|
NCBI chr 3:42,767,500...42,827,470
Ensembl chr 3:42,767,501...42,827,601
|
|
| G
|
Psmb8
|
proteasome 20S subunit beta 8
|
increases expression
|
ISO
|
Nickel results in increased expression of PSMB8 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr20:4,654,068...4,657,049
Ensembl chr20:4,654,068...4,657,031
|
|
| G
|
Psmb9
|
proteasome 20S subunit beta 9
|
increases expression
|
ISO
|
Nickel results in increased expression of PSMB9 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr20:4,668,952...4,674,421
Ensembl chr20:4,668,739...4,674,421
|
|
| G
|
Psmd6
|
proteasome 26S subunit, non-ATPase 6
|
increases expression
|
ISO
|
Nickel results in increased expression of PSMD6 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr15:13,532,675...13,542,682
Ensembl chr15:13,532,675...13,542,682
|
|
| G
|
Psme2
|
proteasome activator subunit 2
|
increases expression
|
ISO
|
Nickel results in increased expression of PSME2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr15:33,048,452...33,053,055
Ensembl chr15:33,048,457...33,053,102
|
|
| G
|
Psme3
|
proteasome activator subunit 3
|
increases expression
|
ISO
|
Nickel results in increased expression of PSME3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:86,757,933...86,765,719
Ensembl chr10:86,757,899...86,818,033
|
|
| G
|
Pstpip1
|
proline-serine-threonine phosphatase-interacting protein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of PSTPIP1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:65,395,328...65,434,616
Ensembl chr 8:65,395,358...65,434,627
|
|
| G
|
Ptafr
|
platelet-activating factor receptor
|
increases expression
|
ISO
|
Nickel results in increased expression of PTAFR mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 5:150,049,322...150,079,060
Ensembl chr 5:150,049,460...150,079,408
|
|
| G
|
Ptbp3
|
polypyrimidine tract binding protein 3
|
increases expression
|
ISO
|
Nickel results in increased expression of PTBP3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:79,108,376...79,194,533
Ensembl chr 5:79,108,376...79,194,508
|
|
| G
|
Ptgds
|
prostaglandin D2 synthase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PTGDS mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:28,680,044...28,682,978
Ensembl chr 3:28,680,044...28,682,978
|
|
| G
|
Ptger2
|
prostaglandin E receptor 2
|
increases expression
|
ISO
|
Nickel results in increased expression of PTGER2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr15:20,694,765...20,708,475
Ensembl chr15:20,696,013...20,708,950
|
|
| G
|
Ptger4
|
prostaglandin E receptor 4
|
increases expression
|
ISO
|
Nickel results in increased expression of PTGER4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:56,061,699...56,074,594
Ensembl chr 2:56,062,890...56,074,135
|
|
| G
|
Ptges
|
prostaglandin E synthase
|
increases expression
|
ISO
|
Nickel results in increased expression of PTGES mRNA
|
CTD |
PMID:12540486 PMID:23195993 PMID:25583101 PMID:27452194 |
|
NCBI chr 3:34,575,643...34,586,987
Ensembl chr 3:34,575,639...34,586,995
|
|
| G
|
Ptgir
|
prostaglandin I2 receptor
|
increases expression
|
ISO
|
Nickel results in increased expression of PTGIR mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:86,707,690...86,710,073
Ensembl chr 1:86,707,503...86,711,874
|
|
| G
|
Ptgr3
|
prostaglandin reductase 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PTGR3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr18:79,729,282...79,738,632
Ensembl chr18:79,729,282...79,738,632
|
|
| G
|
Ptgs2
|
prostaglandin-endoperoxide synthase 2
|
multiple interactions increases expression
|
ISO
|
CAT protein affects the reaction [Nickel results in increased expression of PTGS2]; NFATC4 mRNA affects the reaction [Nickel results in increased expression of PTGS2] Nickel analog results in increased expression of PTGS2 protein; Nickel results in increased expression of PTGS2 mRNA; Nickel results in increased expression of PTGS2 protein Nickel results in increased expression of PTGS2; Nickel results in increased expression of PTGS2 mRNA Dexamethasone inhibits the reaction [Nickel results in increased expression of PTGS2 mRNA]; SB 203580 inhibits the reaction [Nickel results in increased expression of PTGS2 mRNA]
|
CTD |
PMID:19839048 PMID:21486220 PMID:22571318 PMID:24768652 PMID:25583101 PMID:27452194 More...
|
|
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
|
|
| G
|
Pth
|
parathyroid hormone
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of PTH mRNA trichostatin A inhibits the reaction [Nickel affects the expression of PTH mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 1:176,942,901...176,946,034
Ensembl chr 1:176,943,102...176,946,034
|
|
| G
|
Ptn
|
pleiotrophin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PTN mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:66,260,764...66,342,614
Ensembl chr 4:66,260,764...66,342,482
|
|
| G
|
Ptp4a1
|
protein tyrosine phosphatase 4A1
|
increases expression
|
ISO
|
Nickel results in increased expression of PTP4A1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:40,710,250...40,718,176
Ensembl chr 9:40,710,250...40,718,176
|
|
| G
|
Ptpn2
|
protein tyrosine phosphatase, non-receptor type 2
|
increases expression
|
ISO
|
Nickel results in increased expression of PTPN2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr18:63,498,890...63,564,571
Ensembl chr18:63,498,890...63,564,481
|
|
| G
|
Ptpn22
|
protein tyrosine phosphatase, non-receptor type 22
|
affects expression increases expression multiple interactions
|
ISO
|
Nickel affects the expression of PTPN22 mRNA Nickel results in increased expression of PTPN22 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of PTPN22 mRNA]
|
CTD |
PMID:14575637 PMID:24768652 |
|
NCBI chr 2:194,055,165...194,103,209
Ensembl chr 2:194,045,746...194,103,209
|
|
| G
|
Ptpn6
|
protein tyrosine phosphatase, non-receptor type 6
|
increases expression
|
ISO
|
Nickel results in increased expression of PTPN6 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:159,212,320...159,237,069
Ensembl chr 4:159,212,320...159,237,069
|
|
| G
|
Ptpn7
|
protein tyrosine phosphatase, non-receptor type 7
|
increases expression
|
ISO
|
Nickel results in increased expression of PTPN7 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:49,122,679...49,136,096
Ensembl chr13:49,122,609...49,136,094
|
|
| G
|
Ptprb
|
protein tyrosine phosphatase, receptor type, B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PTPRB mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:53,816,197...53,920,760
Ensembl chr 7:53,816,097...53,920,760
|
|
| G
|
Ptprc
|
protein tyrosine phosphatase, receptor type, C
|
increases expression
|
ISO
|
Nickel results in increased expression of PTPRC mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:52,147,717...52,259,810
Ensembl chr13:52,147,717...52,259,746
|
|
| G
|
Ptprcap
|
protein tyrosine phosphatase, receptor type, C-associated protein
|
increases expression
|
ISO
|
Nickel results in increased expression of PTPRCAP mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:210,878,593...210,880,752
Ensembl chr 1:210,878,573...210,881,753
|
|
| G
|
Ptprd
|
protein tyrosine phosphatase, receptor type, D
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PTPRD mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:95,093,221...97,415,498
Ensembl chr 5:95,095,858...96,178,903
|
|
| G
|
Ptpre
|
protein tyrosine phosphatase, receptor type, E
|
increases expression
|
ISO
|
Nickel results in increased expression of PTPRE mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:199,774,195...199,924,646
Ensembl chr 1:199,774,198...199,922,242
|
|
| G
|
Ptpro
|
protein tyrosine phosphatase, receptor type, O
|
increases expression
|
ISO
|
Nickel results in increased expression of PTPRO mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:171,895,104...172,105,911
Ensembl chr 4:171,895,232...172,105,903
|
|
| G
|
Pttg1
|
PTTG1 regulator of sister chromatid separation, securin
|
increases expression
|
ISO
|
Nickel results in increased expression of PTTG1 mRNA
|
CTD |
PMID:19031421 PMID:25583101 |
|
NCBI chr10:28,394,940...28,406,410
Ensembl chr10:28,394,814...28,406,309
|
|
| G
|
Ptx3
|
pentraxin 3
|
increases expression
|
ISO
|
Nickel results in increased expression of PTX3 mRNA
|
CTD |
PMID:12540486 PMID:24768652 PMID:25583101 |
|
NCBI chr 2:152,797,563...152,803,372
Ensembl chr 2:152,781,955...152,803,372
|
|
| G
|
Pudp
|
pseudouridine 5'-phosphatase
|
increases expression
|
ISO
|
Nickel results in increased expression of PUDP mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr18:46,064,867...46,067,247
Ensembl chr18:46,063,292...46,067,443
|
|
| G
|
Pum3
|
pumilio RNA-binding family member 3
|
increases expression
|
ISO
|
Nickel results in increased expression of PUM3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:234,483,482...234,527,718
Ensembl chr 1:234,487,954...234,527,612
|
|
| G
|
Pvr
|
PVR cell adhesion molecule
|
increases expression
|
ISO
|
Nickel results in increased expression of PVR mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:88,689,235...88,704,641
Ensembl chr 1:88,688,981...88,704,630
|
|
| G
|
Pvrig
|
PVR related immunoglobulin domain containing
|
increases expression
|
ISO
|
Nickel results in increased expression of PVRIG mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr12:22,474,441...22,479,191
Ensembl chr12:22,477,694...22,478,894
|
|
| G
|
Pvt1
|
Pvt1 oncogene
|
affects expression multiple interactions increases expression
|
ISO
|
Nickel affects the expression of PVT1 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of PVT1 mRNA] Nickel results in increased expression of PVT1 mRNA
|
CTD |
PMID:14575637 PMID:25583101 |
|
NCBI chr 7:95,545,916...95,769,306
|
|
| G
|
Pwp2
|
PWP2, small subunit processome component
|
increases expression
|
ISO
|
Nickel results in increased expression of PWP2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr20:10,498,998...10,512,631
Ensembl chr20:10,499,013...10,513,309
|
|
| G
|
Pxmp2
|
peroxisomal membrane protein 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PXMP2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr12:52,053,951...52,064,283
Ensembl chr12:52,053,788...52,064,283
|
|
| G
|
Pxmp4
|
peroxisomal membrane protein 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PXMP4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:163,553,582...163,570,829
Ensembl chr 3:163,553,599...163,570,829
|
|
| G
|
Pycard
|
PYD and CARD domain containing
|
increases expression multiple interactions
|
ISO
|
Nickel results in increased expression of PYCARD mRNA Nickel results in increased expression of PYCARD mRNA; Nickel results in increased expression of PYCARD protein [SELENOM protein affects the susceptibility to Nickel] which affects the expression of PYCARD mRNA; [SELENOM protein affects the susceptibility to Nickel] which affects the expression of PYCARD protein; Melatonin affects the reaction [[SELENOM protein affects the susceptibility to Nickel] which affects the expression of PYCARD mRNA]; Melatonin affects the reaction [[SELENOM protein affects the susceptibility to Nickel] which affects the expression of PYCARD protein]; Melatonin inhibits the reaction [Nickel results in increased expression of PYCARD mRNA]; Nickel inhibits the reaction [Melatonin results in decreased expression of PYCARD protein]
|
CTD |
PMID:25583101 PMID:36504304 |
|
NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:192,032,124...192,033,419
|
|
| G
|
Pycr2
|
pyrroline-5-carboxylate reductase 2
|
increases expression
|
ISO
|
Nickel results in increased expression of PYCR2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:95,158,236...95,162,030
Ensembl chr13:95,158,183...95,162,029
|
|
| G
|
Pygb
|
glycogen phosphorylase B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PYGB mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:160,072,141...160,118,930
Ensembl chr 3:160,072,115...160,123,961
|
|
| G
|
Pyroxd2
|
pyridine nucleotide-disulphide oxidoreductase domain 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of PYROXD2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:251,472,609...251,498,316
Ensembl chr 1:251,471,849...251,498,008
|
|
| G
|
Qng1
|
Q-nucleotide N-glycosylase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of QNG1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr17:6,286,801...6,294,400
Ensembl chr17:6,286,827...6,294,399
|
|
| G
|
Qprt
|
quinolinate phosphoribosyltransferase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of QPRT mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:191,148,715...191,164,006
Ensembl chr 1:191,148,713...191,194,162
|
|
| G
|
Qser1
|
glutamine and serine rich 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of QSER1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:111,592,377...111,658,825
Ensembl chr 3:111,595,171...111,657,103
|
|
| G
|
Qsox1
|
quiescin sulfhydryl oxidase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of QSOX1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:70,500,060...70,537,711
Ensembl chr13:70,500,060...70,537,733
|
|
| G
|
Qsox2
|
quiescin sulfhydryl oxidase 2
|
increases expression
|
ISO
|
Nickel results in increased expression of QSOX2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:29,433,091...29,462,739
Ensembl chr 3:29,433,091...29,463,036
|
|
| G
|
R3hdm4
|
R3H domain containing 4
|
increases expression
|
ISO
|
Nickel results in increased expression of R3HDM4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:10,441,032...10,448,143
Ensembl chr 7:10,440,772...10,448,143
|
|
| G
|
Rab10
|
RAB10, member RAS oncogene family
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RAB10 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 6:31,974,858...32,039,554
Ensembl chr 6:31,986,921...32,039,733
|
|
| G
|
Rab20
|
RAB20, member RAS oncogene family
|
increases expression
|
ISO
|
Nickel results in increased expression of RAB20 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr16:84,721,427...84,745,610
Ensembl chr16:84,721,427...84,745,610
|
|
| G
|
Rab22a
|
RAB22A, member RAS oncogene family
|
increases expression
|
ISO
|
Nickel results in increased expression of RAB22A mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:182,877,746...182,924,400
Ensembl chr 3:182,877,998...182,924,400
|
|
| G
|
Rab27a
|
RAB27A, member RAS oncogene family
|
increases expression
|
ISO
|
Nickel results in increased expression of RAB27A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:82,663,373...82,717,267
Ensembl chr 8:82,663,276...82,717,262
|
|
| G
|
Rab29
|
RAB29, member RAS oncogene family
|
increases expression
|
ISO
|
Nickel results in increased expression of RAB29 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:45,859,930...45,865,468
Ensembl chr13:45,859,961...45,865,610
|
|
| G
|
Rab30
|
RAB30, member RAS oncogene family
|
increases expression
|
ISO
|
Nickel results in increased expression of RAB30 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 1:156,216,137...156,310,778
Ensembl chr 1:156,216,137...156,310,778
|
|
| G
|
Rab31
|
RAB31, member RAS oncogene family
|
increases expression
|
ISO
|
Nickel results in increased expression of RAB31 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:112,693,596...112,828,104
Ensembl chr 9:112,693,597...112,828,092
|
|
| G
|
Rab32
|
RAB32, member RAS oncogene family
|
multiple interactions
|
ISO
|
MT1 affects the reaction [Nickel affects the expression of RAB32 mRNA]; MT2 affects the reaction [Nickel affects the expression of RAB32 mRNA]
|
CTD |
PMID:16166738 |
|
NCBI chr 1:6,766,448...6,781,258
Ensembl chr 1:6,766,455...6,781,258
|
|
| G
|
Rab3b
|
RAB3B, member RAS oncogene family
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RAB3B mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:128,859,034...128,926,087
Ensembl chr 5:128,841,716...128,926,086
|
|
| G
|
Rab40b
|
Rab40b, member RAS oncogene family
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RAB40B mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr10:107,129,801...107,157,375
Ensembl chr10:107,129,801...107,157,457
|
|
| G
|
Rab6b
|
RAB6B, member RAS oncogene family
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RAB6B mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:112,574,223...112,642,911
Ensembl chr 8:112,574,167...112,642,907
|
|
| G
|
Rab7a
|
RAB7A, member RAS oncogene family
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RAB7A mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 4:122,019,281...122,068,067
Ensembl chr 4:121,983,938...122,064,185
|
|
| G
|
Rab8b
|
RAB8B, member RAS oncogene family
|
increases expression
|
ISO
|
Nickel results in increased expression of RAB8B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:76,340,106...76,417,638
Ensembl chr 8:76,340,113...76,417,885
|
|
| G
|
Rab9b
|
RAB9B, member RAS oncogene family
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RAB9B mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:105,013,178...105,023,872
Ensembl chr X:105,013,104...105,034,319
|
|
| G
|
Rabif
|
RAB interacting factor
|
increases expression
|
ISO
|
Nickel results in increased expression of RABIF mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:48,488,370...48,500,853
Ensembl chr13:48,488,348...48,502,013
|
|
| G
|
Rac2
|
Rac family small GTPase 2
|
increases expression
|
ISO
|
Nickel results in increased expression of RAC2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:111,981,825...112,009,201
Ensembl chr 7:111,996,742...112,009,267
|
|
| G
|
Rad18
|
RAD18 E3 ubiquitin protein ligase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RAD18 mRNA
|
CTD |
PMID:22641096 |
|
NCBI chr 4:147,291,463...147,376,904
Ensembl chr 4:147,291,276...147,376,869
|
|
| G
|
Rad51
|
RAD51 recombinase
|
increases expression
|
ISO
|
Nickel results in increased expression of RAD51 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:126,554,210...126,578,888
Ensembl chr 3:126,554,190...126,579,469
|
|
| G
|
Rad51ap1
|
RAD51 associated protein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of RAD51AP1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:161,445,610...161,458,661
Ensembl chr 4:161,445,512...161,458,680
|
|
| G
|
Rala
|
RAS like proto-oncogene A
|
increases expression
|
ISO
|
Nickel results in increased expression of RALA mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr17:51,787,682...51,840,738
Ensembl chr17:51,787,699...51,840,733
|
|
| G
|
Ralgps2
|
Ral GEF with PH domain and SH3 binding motif 2
|
increases expression
|
ISO
|
Nickel results in increased expression of RALGPS2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:71,474,835...71,654,791
Ensembl chr13:71,474,835...71,606,739
|
|
| G
|
Ran
|
RAN, member RAS oncogene family
|
increases expression
|
ISO
|
Nickel results in increased expression of RAN mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr12:33,311,155...33,314,339
Ensembl chr12:33,311,158...33,314,317
|
|
| G
|
Ranbp1
|
RAN binding protein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of RANBP1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:96,246,912...96,255,145
Ensembl chr11:96,246,740...96,255,145
|
|
| G
|
Rangap1
|
RAN GTPase activating protein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of RANGAP1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:115,104,820...115,130,564
Ensembl chr 7:115,104,823...115,130,564
|
|
| G
|
Rap1a
|
RAP1A, member of RAS oncogene family
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RAP1A mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:195,896,967...195,974,851
Ensembl chr 2:195,896,971...195,974,808
|
|
| G
|
Rapgef3
|
Rap guanine nucleotide exchange factor 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RAPGEF3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:130,754,883...130,777,303
Ensembl chr 7:130,754,871...130,777,668
|
|
| G
|
Rarres2
|
retinoic acid receptor responder 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RARRES2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:78,853,450...78,856,652
Ensembl chr 4:78,853,453...78,856,457
|
|
| G
|
Rasal3
|
RAS protein activator like 3
|
increases expression
|
ISO
|
Nickel results in increased expression of RASAL3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:12,047,090...12,061,883
Ensembl chr 7:12,047,090...12,061,883
|
|
| G
|
Rasd2
|
RASD family, member 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RASD2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr19:13,600,028...13,610,753
Ensembl chr19:13,599,986...13,610,753
|
|
| G
|
Rasef
|
RAS and EF hand domain containing
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RASEF mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 5:92,595,148...92,665,526
Ensembl chr 5:92,595,148...92,666,117
|
|
| G
|
Rasgef1b
|
RasGEF domain family, member 1B
|
increases expression
|
ISO
|
Nickel results in increased expression of RASGEF1B mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr14:10,164,366...10,684,184
Ensembl chr14:10,644,521...10,697,296
|
|
| G
|
Rasgrp1
|
RAS guanyl releasing protein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of RASGRP1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:124,624,039...124,684,079
Ensembl chr 3:124,622,313...124,684,434
|
|
| G
|
Rasgrp2
|
RAS guanyl releasing protein 2
|
increases expression
|
ISO
|
Nickel results in increased expression of RASGRP2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:213,135,034...213,152,246
Ensembl chr 1:213,136,015...213,151,884
|
|
| G
|
Rasgrp4
|
RAS guanyl releasing protein 4
|
increases expression
|
ISO
|
Nickel results in increased expression of RASGRP4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:93,560,513...93,580,321
Ensembl chr 1:93,560,513...93,580,323
|
|
| G
|
Rasl11b
|
RAS-like family 11 member B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RASL11B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr14:34,369,029...34,373,250
Ensembl chr14:34,368,726...34,373,250
|
|
| G
|
Rasl12
|
RAS-like, family 12
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RASL12 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:74,813,000...74,827,041
Ensembl chr 8:74,813,000...74,827,897
|
|
| G
|
Rassf1
|
Ras association domain family member 1
|
increases expression
|
ISO
|
Nickel analog results in increased expression of RASSF1 mRNA; Nickel analog results in increased expression of RASSF1 protein
|
CTD |
PMID:24579805 |
|
NCBI chr 8:117,103,665...117,114,805
Ensembl chr 8:117,103,362...117,114,805
|
|
| G
|
Rassf2
|
Ras association domain family member 2
|
increases expression
|
ISO
|
Nickel results in increased expression of RASSF2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:139,697,187...139,733,402
Ensembl chr 3:139,697,187...139,733,368
|
|
| G
|
Rassf4
|
Ras association domain family member 4
|
increases expression
|
ISO
|
Nickel results in increased expression of RASSF4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:151,569,984...151,605,203
Ensembl chr 4:151,569,984...151,604,883
|
|
| G
|
Rassf5
|
Ras association domain family member 5
|
increases expression
|
ISO
|
Nickel results in increased expression of RASSF5 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:45,189,768...45,255,277
Ensembl chr13:45,189,804...45,255,277
|
|
| G
|
Rassf6
|
Ras association domain family member 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RASSF6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:17,717,505...17,757,507
Ensembl chr14:17,717,567...17,760,378
|
|
| G
|
Rassf9
|
Ras association domain family member 9
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RASSF9 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:39,486,257...39,518,090
Ensembl chr 7:39,409,870...39,519,675
|
|
| G
|
Rb1
|
RB transcriptional corepressor 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RB1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857
|
|
| G
|
Rbck1
|
RANBP2-type and C3HC4-type zinc finger containing 1
|
increases expression
|
ISO
|
Nickel results in increased expression of RBCK1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 3:161,249,389...161,266,321
Ensembl chr 3:161,249,390...161,266,032
|
|
| G
|
Rbm15
|
RNA binding motif protein 15
|
increases expression
|
ISO
|
Nickel results in increased expression of RBM15 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 2:197,634,174...197,642,697
Ensembl chr 2:197,583,002...197,643,037
|
|
| G
|
Rbm20
|
RNA binding motif protein 20
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RBM20 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:262,671,311...262,912,551
Ensembl chr 1:262,688,978...262,891,364
|
|
| G
|
Rbm24
|
RNA binding motif protein 24
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RBM24 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr17:18,481,893...18,494,440
Ensembl chr17:18,481,900...18,494,604
|
|
| G
|
Rbm28
|
RNA binding motif protein 28
|
increases expression
|
ISO
|
Nickel results in increased expression of RBM28 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:58,688,337...58,727,312
Ensembl chr 4:58,688,337...58,726,968
|
|
| G
|
Rbm3
|
RNA binding motif protein 3
|
increases expression
|
ISO
|
Nickel results in increased expression of RBM3 mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr X:17,020,863...17,024,341
Ensembl chr X:17,020,864...17,024,841
|
|
| G
|
Rbm6
|
RNA binding motif protein 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RBM6 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 8:117,327,607...117,431,397
Ensembl chr 8:117,331,325...117,431,397
|
|
| G
|
Rbms3
|
RNA binding motif, single stranded interacting protein 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RBMS3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:125,183,311...125,970,239
Ensembl chr 8:125,183,315...126,503,586
|
|
| G
|
Rbp1
|
retinol binding protein 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RBP1 mRNA
|
CTD |
PMID:12540486 PMID:24768652 |
|
NCBI chr 8:107,904,589...107,926,109
Ensembl chr 8:107,887,417...107,983,847
|
|
| G
|
Rbp7
|
retinol binding protein 7
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RBP7 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:165,169,700...165,177,427
Ensembl chr 5:165,172,785...165,177,399
|
|
| G
|
Rbpms2
|
RNA binding protein, mRNA processing factor 2
|
increases expression decreases expression
|
ISO
|
Nickel results in increased expression of RBPMS2 mRNA Nickel results in decreased expression of RBPMS2 mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 8:75,048,159...75,079,393
Ensembl chr 8:75,048,263...75,079,396
|
|
| G
|
Rcan1
|
regulator of calcineurin 1
|
increases expression
|
ISO
|
Nickel results in increased expression of RCAN1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr11:45,108,123...45,188,065
Ensembl chr11:45,108,124...45,118,236
|
|
| G
|
Rcan2
|
regulator of calcineurin 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RCAN2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 9:24,456,861...24,674,234
Ensembl chr 9:24,456,861...24,672,189
|
|
| G
|
Rcbtb2
|
RCC1 and BTB domain containing protein 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RCBTB2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr15:54,729,367...54,774,004
Ensembl chr15:54,729,332...54,793,313
|
|
| G
|
Rcc1
|
regulator of chromosome condensation 1
|
increases expression
|
ISO
|
Nickel results in increased expression of RCC1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:149,810,037...149,828,475
Ensembl chr 5:149,810,689...149,828,523
|
|
| G
|
Rcsd1
|
RCSD domain containing 1
|
increases expression
|
ISO
|
Nickel results in increased expression of RCSD1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:80,434,878...80,497,312
Ensembl chr13:80,434,878...80,498,931
|
|
| G
|
Rdh5
|
retinol dehydrogenase 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RDH5 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:1,912,120...1,931,836
Ensembl chr 7:1,925,335...1,936,049
|
|
| G
|
Rec8
|
REC8 meiotic recombination protein
|
increases expression
|
ISO
|
Nickel results in increased expression of REC8 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr15:33,079,818...33,087,283
Ensembl chr15:33,079,801...33,087,282
|
|
| G
|
Reck
|
reversion-inducing-cysteine-rich protein with kazal motifs
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RECK mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:62,898,717...62,965,274
Ensembl chr 5:62,898,668...62,965,270
|
|
| G
|
Recql
|
RecQ like helicase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RECQL mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 4:177,039,351...177,063,968
Ensembl chr 4:177,035,128...177,063,838
|
|
| G
|
Reep1
|
receptor accessory protein 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of REEP1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:105,303,974...105,420,611
Ensembl chr 4:105,303,969...105,420,602
|
|
| G
|
Reep6
|
receptor accessory protein 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of REEP6 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 7:10,024,601...10,031,507
Ensembl chr 7:10,024,602...10,031,740
|
|
| G
|
Rel
|
REL proto-oncogene, NF-kB subunit
|
multiple interactions
|
ISO
|
[Nickel co-treated with Lipopolysaccharides] affects the localization of REL protein
|
CTD |
PMID:22287454 |
|
NCBI chr14:101,891,238...101,922,324
Ensembl chr14:101,891,243...101,921,938
|
|
| G
|
Rela
|
RELA proto-oncogene, NF-kB subunit
|
multiple interactions
|
ISO
|
[Copper co-treated with Lead co-treated with Cadmium co-treated with Zinc co-treated with Mercury co-treated with Chromium co-treated with Manganese co-treated with Nickel] results in increased expression of RELA protein; [Zinc co-treated with Nickel co-treated with Cobalt] affects the reaction [Dietary Fats affects the expression of RELA mRNA] [Asbestos, Serpentine results in increased abundance of [Magnesium co-treated with Chromium co-treated with Nickel co-treated with Cobalt]] which results in increased phosphorylation of RELA protein; [Nickel co-treated with Lipopolysaccharides] affects the localization of RELA protein
|
CTD |
PMID:22287454 PMID:23503329 PMID:28035397 PMID:38605572 |
|
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
|
|
| G
|
Relb
|
RELB proto-oncogene, NF-kB subunit
|
increases expression
|
ISO
|
Nickel results in increased expression of RELB mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr 1:88,385,717...88,413,380
Ensembl chr 1:88,385,717...88,413,420
|
|
| G
|
Reln
|
reelin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RELN mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:13,628,440...14,055,201
Ensembl chr 4:13,628,399...14,055,162
|
|
| G
|
Relt
|
RELT, TNF receptor
|
increases expression
|
ISO
|
Nickel results in increased expression of RELT mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:164,619,059...164,636,707
Ensembl chr 1:164,619,059...164,636,670
|
|
| G
|
Reps2
|
RALBP1 associated Eps domain containing 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of REPS2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:35,681,260...35,954,103
Ensembl chr X:35,681,263...35,954,103
|
|
| G
|
Rerg
|
RAS-like, estrogen-regulated, growth-inhibitor
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RERG mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:171,712,794...171,821,268
Ensembl chr 4:171,712,794...171,820,903
|
|
| G
|
Rergl
|
RERG like
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RERGL mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:174,114,882...174,123,972
Ensembl chr 4:174,114,882...174,124,080
|
|
| G
|
Resf1
|
retroelement silencing factor 1
|
increases expression
|
ISO
|
Nickel results in increased expression of RESF1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:184,057,165...184,093,374
Ensembl chr 4:184,057,010...184,098,429
|
|
| G
|
Ret
|
ret proto-oncogene
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RET mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:152,998,344...153,040,556
Ensembl chr 4:152,998,812...153,040,556
|
|
| G
|
Retnlb
|
resistin like beta
|
increases expression
|
ISO
|
Nickel results in increased expression of RETNLB mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr11:65,446,433...65,448,319
Ensembl chr11:65,446,434...65,448,319
|
|
| G
|
Rflnb
|
refilin B
|
increases expression
|
ISO
|
Nickel results in increased expression of RFLNB mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:61,391,947...61,398,224
Ensembl chr10:61,390,659...61,398,224
|
|
| G
|
Rftn2
|
raftlin family member 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RFTN2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:64,146,062...64,202,342
Ensembl chr 9:64,124,865...64,215,186
|
|
| G
|
Rfx5
|
regulatory factor X5
|
increases expression
|
ISO
|
Nickel results in increased expression of RFX5 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 2:185,210,206...185,217,735
Ensembl chr 2:185,210,217...185,217,743
|
|
| G
|
Rgcc
|
regulator of cell cycle
|
increases expression
|
ISO
|
Nickel results in increased expression of RGCC mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr15:61,071,574...61,084,408
Ensembl chr15:61,071,574...61,084,408
|
|
| G
|
RGD1359108
|
similar to RIKEN cDNA 3110043O21
|
increases expression
|
ISO
|
Nickel results in increased expression of C9ORF72 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:54,562,570...54,587,649
Ensembl chr 5:54,562,570...54,587,637
|
|
| G
|
Rgmb
|
repulsive guidance molecule BMP co-receptor b
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RGMB mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 1:65,439,748...65,465,149
Ensembl chr 1:65,441,410...65,465,098
|
|
| G
|
Rgn
|
regucalcin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RGN mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:4,172,537...4,190,112
Ensembl chr X:4,172,537...4,190,251
|
|
| G
|
Rgs1
|
regulator of G-protein signaling 1
|
increases expression
|
ISO
|
Nickel results in increased expression of RGS1 mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr13:58,568,844...58,573,187
Ensembl chr13:58,568,844...58,573,187
|
|
| G
|
Rgs16
|
regulator of G-protein signaling 16
|
increases expression
|
ISO
|
Nickel results in increased expression of RGS16 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:68,421,480...68,443,312
Ensembl chr13:68,438,120...68,443,313
|
|
| G
|
Rgs18
|
regulator of G-protein signaling 18
|
increases expression
|
ISO
|
Nickel results in increased expression of RGS18 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:59,043,431...59,066,342
Ensembl chr13:59,043,431...59,066,342
|
|
| G
|
Rgs19
|
regulator of G-protein signaling 19
|
increases expression
|
ISO
|
Nickel results in increased expression of RGS19 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:189,182,041...189,190,494
Ensembl chr 3:189,182,383...189,190,736
|
|
| G
|
Rgs20
|
regulator of G-protein signaling 20
|
increases expression
|
ISO
|
Nickel results in increased expression of RGS20 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:19,282,249...19,412,122
Ensembl chr 5:19,282,153...19,413,286
|
|
| G
|
Rgs22
|
regulator of G-protein signaling 22
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RGS22 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 7:69,073,681...69,194,041
Ensembl chr 7:69,075,562...69,194,102
|
|
| G
|
Rgs5
|
regulator of G-protein signaling 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RGS5 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:84,381,077...84,417,875
Ensembl chr13:84,380,910...84,421,352
|
|
| G
|
Rgs6
|
regulator of G-protein signaling 6
|
increases expression
|
ISO
|
Nickel results in increased expression of RGS6 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 6:107,875,883...108,527,472
Ensembl chr 6:107,876,039...108,555,840
|
|
| G
|
Rhbdd2
|
rhomboid domain containing 2
|
increases expression
|
ISO
|
Nickel results in increased expression of RHBDD2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr12:26,680,206...26,690,926
Ensembl chr12:26,680,969...26,691,080
|
|
| G
|
Rhbdf2
|
rhomboid 5 homolog 2
|
increases expression
|
ISO
|
Nickel results in increased expression of RHBDF2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:102,331,991...102,359,117
Ensembl chr10:102,331,991...102,359,117
|
|
| G
|
Rhobtb3
|
Rho-related BTB domain containing 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RHOBTB3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:7,094,972...7,201,507
Ensembl chr 2:7,095,253...7,150,906
|
|
| G
|
Rhof
|
ras homolog family member F, filopodia associated
|
increases expression
|
ISO
|
Nickel results in increased expression of RHOF mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr12:39,082,413...39,107,528
Ensembl chr12:39,091,979...39,107,528
|
|
| G
|
Rhog
|
ras homolog family member G
|
increases expression
|
ISO
|
Nickel results in increased expression of RHOG mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:166,030,685...166,046,254
Ensembl chr 1:166,017,427...166,044,787
|
|
| G
|
Rhoh
|
ras homolog family member H
|
increases expression
|
ISO
|
Nickel results in increased expression of RHOH mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr14:42,694,860...42,725,690
Ensembl chr14:42,693,413...42,749,967
|
|
| G
|
Rhpn2
|
rhophilin, Rho GTPase binding protein 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RHPN2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:97,128,054...97,188,803
Ensembl chr 1:97,127,697...97,188,803
|
|
| G
|
Rig1
|
RNA sensor RIG-1
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of RIGI mRNA Nickel results in increased expression of RIGI mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 5:60,117,398...60,165,995
Ensembl chr 5:60,117,398...60,165,995
|
|
| G
|
Rimbp2
|
RIMS binding protein 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RIMBP2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr12:33,383,646...33,582,259
Ensembl chr12:33,384,007...33,593,999
|
|
| G
|
Rimoc1
|
RAB7A interacting MON1-CCZ1 complex subunit 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RIMOC1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 2:54,917,383...54,931,577
Ensembl chr 2:54,917,383...54,931,874
|
|
| G
|
Rims2
|
regulating synaptic membrane exocytosis 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RIMS2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 7:72,133,004...72,644,059
Ensembl chr 7:72,133,170...72,645,499
|
|
| G
|
Ripk1
|
receptor interacting serine/threonine kinase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of RIPK1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr17:31,044,983...31,077,167
Ensembl chr17:31,044,994...31,077,167
|
|
| G
|
Ripk3
|
receptor-interacting serine-threonine kinase 3
|
increases expression
|
ISO
|
Nickel results in increased expression of RIPK3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr15:33,253,071...33,262,025
Ensembl chr15:33,253,071...33,262,025
|
|
| G
|
Ripor2
|
RHO family interacting cell polarization regulator 2
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of RIPOR2 mRNA Nickel results in increased expression of RIPOR2 mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr17:40,751,771...40,975,611
Ensembl chr17:40,751,771...40,975,337
|
|
| G
|
Ripor3
|
RIPOR family member 3
|
increases expression
|
ISO
|
Nickel results in increased expression of RIPOR3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:177,106,436...177,179,423
Ensembl chr 3:177,106,892...177,179,095
|
|
| G
|
Rit1
|
Ras-like without CAAX 1
|
increases expression
|
ISO
|
Nickel results in increased expression of RIT1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:176,478,616...176,493,269
Ensembl chr 2:176,478,596...176,494,684
|
|
| G
|
Rlf
|
RLF zinc finger
|
increases expression
|
ISO
|
Nickel results in increased expression of RLF mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 5:139,996,782...140,052,419
Ensembl chr 5:139,996,782...140,052,419
|
|
| G
|
Rlim
|
ring finger protein, LIM domain interacting
|
increases expression
|
ISO
|
Nickel results in increased expression of RLIM mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr X:73,048,983...73,070,302
Ensembl chr X:73,054,098...73,069,992
|
|
| G
|
Rnase4
|
ribonuclease A family member 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RNASE4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr15:26,786,287...26,803,634
Ensembl chr15:26,786,079...26,803,639
|
|
| G
|
Rnase6
|
ribonuclease A family member 6
|
increases expression
|
ISO
|
Nickel results in increased expression of RNASE6 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr15:26,827,896...26,830,807
Ensembl chr15:26,827,009...26,830,825
|
|
| G
|
Rnasel
|
ribonuclease L
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RNASEL mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr13:68,446,641...68,460,804
Ensembl chr13:68,446,882...68,459,557
|
|
| G
|
Rnf11
|
ring finger protein 11
|
multiple interactions
|
ISO
|
MT1 affects the reaction [Nickel affects the expression of RNF11 mRNA]; MT2 affects the reaction [Nickel affects the expression of RNF11 mRNA]
|
CTD |
PMID:16166738 |
|
NCBI chr 5:129,441,071...129,471,799
Ensembl chr 5:129,442,309...129,463,538
|
|
| G
|
Rnf111
|
ring finger protein 111
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RNF111 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 8:79,984,831...80,061,022
Ensembl chr 8:79,984,837...80,060,984
|
|
| G
|
Rnf114
|
ring finger protein 114
|
multiple interactions
|
ISO
|
MT1 affects the reaction [Nickel affects the expression of RNF114 mRNA]; MT2 affects the reaction [Nickel affects the expression of RNF114 mRNA]
|
CTD |
PMID:16166738 |
|
NCBI chr 3:176,641,456...176,653,262
Ensembl chr 3:176,641,499...176,671,960
|
|
| G
|
Rnf128
|
ring finger protein 128
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RNF128 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:107,968,973...108,087,037
Ensembl chr X:107,972,348...108,087,288
|
|
| G
|
Rnf13
|
ring finger protein 13
|
multiple interactions
|
ISO
|
MT1 affects the reaction [Nickel affects the expression of RNF13 mRNA]; MT2 affects the reaction [Nickel affects the expression of RNF13 mRNA]
|
CTD |
PMID:16166738 |
|
NCBI chr 2:144,076,526...144,211,520
Ensembl chr 2:144,077,916...144,211,798
|
|
| G
|
Rnf144b
|
ring finger protein 144B
|
increases expression
|
ISO
|
Nickel results in increased expression of RNF144B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr17:17,637,564...17,786,685
Ensembl chr17:17,639,079...17,769,037
|
|
| G
|
Rnf150
|
ring finger protein 150
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RNF150 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr19:41,912,276...42,133,217
Ensembl chr19:41,912,276...42,133,217
|
|
| G
|
Rnf157
|
ring finger protein 157
|
increases expression
|
ISO
|
Nickel results in increased expression of RNF157 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr10:102,070,842...102,138,738
Ensembl chr10:102,070,842...102,155,802
|
|
| G
|
Rnf166
|
ring finger protein 166
|
increases expression
|
ISO
|
Nickel results in increased expression of RNF166 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr19:67,437,974...67,447,814
Ensembl chr19:67,437,974...67,447,814
|
|
| G
|
Rnf180
|
ring finger protein 180
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RNF180 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:38,064,026...38,244,854
Ensembl chr 2:38,064,031...38,265,358
|
|
| G
|
Rnf19a
|
ring finger protein 19A, RBR E3 ubiquitin protein ligase
|
multiple interactions
|
ISO
|
MT1 affects the reaction [Nickel affects the expression of RNF19A mRNA]; MT2 affects the reaction [Nickel affects the expression of RNF19A mRNA]
|
CTD |
PMID:16166738 |
|
NCBI chr 7:69,310,947...69,350,567
Ensembl chr 7:69,310,947...69,350,225
|
|
| G
|
Rnf19b
|
ring finger protein 19B
|
increases expression
|
ISO
|
Nickel results in increased expression of RNF19B mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr 5:146,690,453...146,715,729
Ensembl chr 5:146,690,577...146,714,394
|
|
| G
|
Rnf213
|
ring finger protein 213
|
increases expression
|
ISO
|
Nickel results in increased expression of RNF213 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:105,154,873...105,254,148
Ensembl chr10:105,157,904...105,254,148
|
|
| G
|
Rnf34
|
ring finger protein 34
|
increases expression
|
ISO
|
Nickel results in increased expression of RNF34 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr12:39,364,461...39,385,391
Ensembl chr12:39,355,578...39,385,340
|
|
| G
|
Rnf39
|
ring finger protein 39
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RNF39 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr20:1,610,027...1,615,516
Ensembl chr20:1,610,026...1,612,323
|
|
| G
|
Rngtt
|
RNA guanylyltransferase and 5'-phosphatase
|
increases expression
|
ISO
|
Nickel results in increased expression of RNGTT mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 5:52,503,335...52,709,604
Ensembl chr 5:52,503,313...52,709,597
|
|
| G
|
Rnmt
|
RNA (guanine-7-) methyltransferase
|
increases expression
|
ISO
|
Nickel results in increased expression of RNMT mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr18:64,156,067...64,179,601
Ensembl chr18:64,156,154...64,179,500
|
|
| G
|
Robo2
|
roundabout guidance receptor 2
|
decreases expression multiple interactions
|
ISO EXP
|
Nickel results in decreased expression of ROBO2 mRNA [nickel sulfate results in increased abundance of Nickel] which results in decreased expression of ROBO2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 PMID:31734292 |
|
NCBI chr11:26,015,919...27,583,750
Ensembl chr11:26,015,919...26,876,185
|
|
| G
|
Ropn1
|
rhophilin associated tail protein 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of ROPN1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:79,603,053...79,632,344
Ensembl chr11:79,603,055...79,632,344
|
|
| G
|
Rora
|
RAR-related orphan receptor A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RORA mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 8:78,182,710...78,915,730
Ensembl chr 8:78,182,620...78,915,730
|
|
| G
|
Rorc
|
RAR-related orphan receptor C
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RORC mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:184,698,779...184,723,942
Ensembl chr 2:184,698,818...184,724,566
|
|
| G
|
Rp2
|
RP2 activator of ARL3 GTPase
|
increases expression
|
ISO
|
Nickel results in increased expression of RP2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:4,426,071...4,470,200
Ensembl chr X:4,403,052...4,530,576
|
|
| G
|
Rpa2
|
replication protein A2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RPA2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 5:150,260,668...150,271,329
Ensembl chr 5:150,260,723...150,271,546
|
|
| G
|
Rpain
|
RPA interacting protein
|
increases expression
|
ISO
|
Nickel results in increased expression of RPAIN mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:56,190,975...56,198,490
Ensembl chr10:56,190,967...56,199,685
|
|
| G
|
Rpap3
|
RNA polymerase II associated protein 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RPAP3 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 7:130,689,923...130,719,411
Ensembl chr 7:130,689,929...130,719,247
|
|
| G
|
Rpe
|
ribulose-5-phosphate-3-epimerase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RPE mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 9:75,640,867...75,661,009
Ensembl chr 9:75,640,982...75,661,643
|
|
| G
|
Rpl15
|
ribosomal protein L15
|
multiple interactions
|
ISO
|
MT1 affects the reaction [Nickel affects the expression of RPL15 mRNA]; MT2 affects the reaction [Nickel affects the expression of RPL15 mRNA]
|
CTD |
PMID:16166738 |
|
NCBI chr15:9,934,663...9,937,946
Ensembl chr15:9,934,679...9,938,308
|
|
| G
|
Rpl19
|
ribosomal protein L19
|
multiple interactions
|
ISO
|
MT1 affects the reaction [Nickel affects the expression of RPL19 mRNA]; MT2 affects the reaction [Nickel affects the expression of RPL19 mRNA]
|
CTD |
PMID:16166738 |
|
NCBI chr10:83,514,509...83,522,352
Ensembl chr10:83,515,464...83,522,352
|
|
| G
|
Rpl29
|
ribosomal protein L29
|
multiple interactions
|
ISO
|
MT1 affects the reaction [Nickel affects the expression of RPL29 mRNA]; MT2 affects the reaction [Nickel affects the expression of RPL29 mRNA]
|
CTD |
PMID:16166738 |
|
NCBI chr 8:115,056,443...115,949,677
Ensembl chr 8:115,947,394...115,950,565
|
|
| G
|
Rpl31
|
ribosomal protein L31
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RPL31 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:49,143,044...49,147,155
Ensembl chr 9:49,142,955...49,147,155
|
|
| G
|
Rpl35
|
ribosomal protein L35
|
multiple interactions
|
ISO
|
MT1 affects the reaction [Nickel affects the expression of RPL35 mRNA]; MT2 affects the reaction [Nickel affects the expression of RPL35 mRNA]
|
CTD |
PMID:16166738 |
|
NCBI chr 3:43,162,960...43,166,485
Ensembl chr 3:43,162,764...43,165,947
|
|
| G
|
Rpl36a
|
ribosomal protein L36A
|
multiple interactions
|
ISO
|
MT1 affects the reaction [Nickel affects the expression of RPL36A mRNA]; MT2 affects the reaction [Nickel affects the expression of RPL36A mRNA]
|
CTD |
PMID:16166738 |
|
NCBI chr X:102,058,573...102,062,162
Ensembl chr20:22,034,086...22,034,406
|
|
| G
|
Rpl4
|
ribosomal protein L4
|
multiple interactions
|
ISO
|
MT1 affects the reaction [Nickel affects the expression of RPL4 mRNA]; MT2 affects the reaction [Nickel affects the expression of RPL4 mRNA]
|
CTD |
PMID:16166738 |
|
NCBI chr 8:73,566,477...73,571,600
Ensembl chr 8:73,566,466...73,571,788
|
|
| G
|
Rplp0
|
ribosomal protein lateral stalk subunit P0
|
multiple interactions
|
ISO
|
MT1 affects the reaction [Nickel affects the expression of RPLP0 mRNA]; MT2 affects the reaction [Nickel affects the expression of RPLP0 mRNA]
|
CTD |
PMID:16166738 |
|
NCBI chr12:46,715,121...46,718,390
Ensembl chr12:46,715,124...46,718,422
|
|
| G
|
Rpp40
|
ribonuclease P/MRP subunit p40
|
increases expression
|
ISO
|
Nickel results in increased expression of RPP40 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr17:29,153,203...29,162,241
Ensembl chr17:29,153,180...29,162,241
|
|
| G
|
Rprml
|
reprimo-like
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RPRML mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:89,060,280...89,061,284
Ensembl chr10:89,059,522...89,063,831
|
|
| G
|
Rps14
|
ribosomal protein S14
|
multiple interactions
|
ISO
|
MT1 affects the reaction [Nickel affects the expression of RPS14 mRNA]; MT2 affects the reaction [Nickel affects the expression of RPS14 mRNA]
|
CTD |
PMID:16166738 |
|
NCBI chr18:56,492,010...56,503,092
Ensembl chr18:56,498,245...56,503,091
|
|
| G
|
Rps16
|
ribosomal protein S16
|
increases expression
|
ISO
|
Nickel results in increased expression of RPS16 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:92,770,658...92,773,603
Ensembl chr19:56,922,246...56,923,020 Ensembl chr 1:56,922,246...56,923,020
|
|
| G
|
Rps26
|
ribosomal protein S26
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RPS26 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 7:1,641,846...1,643,404
Ensembl chr 7:1,641,421...1,643,399
|
|
| G
|
Rps27
|
ribosomal protein S27
|
increases expression
|
ISO
|
Nickel results in increased expression of RPS27 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:177,963,499...177,964,708
Ensembl chr 2:177,963,496...177,964,607 Ensembl chr12:177,963,496...177,964,607
|
|
| G
|
Rps3
|
ribosomal protein S3
|
multiple interactions
|
ISO
|
MT1 affects the reaction [Nickel affects the expression of RPS3 mRNA]; MT2 affects the reaction [Nickel affects the expression of RPS3 mRNA]
|
CTD |
PMID:16166738 |
|
NCBI chr 1:163,190,476...163,195,885
Ensembl chr 1:163,189,842...163,195,776
|
|
| G
|
Rps6ka1
|
ribosomal protein S6 kinase A1
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of RPS6KA1 mRNA Nickel results in increased expression of RPS6KA1 mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 5:151,362,819...151,402,064
Ensembl chr 5:151,362,819...151,476,044
|
|
| G
|
Rps6ka3
|
ribosomal protein S6 kinase A3
|
increases expression
|
ISO
|
Nickel results in increased expression of RPS6KA3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr X:39,325,926...39,432,017
Ensembl chr X:39,325,926...39,433,678
|
|
| G
|
Rps6ka4
|
ribosomal protein S6 kinase A4
|
increases expression
|
ISO
|
Nickel results in increased expression of RPS6KA4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:213,451,026...213,461,982
Ensembl chr 1:213,451,027...213,461,982
|
|
| G
|
Rps6ka6
|
ribosomal protein S6 kinase A6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RPS6KA6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:80,537,723...80,638,910
Ensembl chr X:80,537,723...80,692,148
|
|
| G
|
Rps7
|
ribosomal protein S7
|
multiple interactions
|
ISO
|
MT1 affects the reaction [Nickel affects the expression of RPS7 mRNA]; MT2 affects the reaction [Nickel affects the expression of RPS7 mRNA]
|
CTD |
PMID:16166738 |
|
NCBI chr 6:50,994,581...50,999,447
|
|
| G
|
Rptn
|
repetin
|
multiple interactions decreases expression
|
ISO
|
trichostatin A inhibits the reaction [Nickel affects the expression of RPTN mRNA] Nickel results in decreased expression of RPTN mRNA
|
CTD |
PMID:14575637 PMID:24768652 PMID:25583101 |
|
NCBI chr 2:181,743,463...181,750,101
Ensembl chr 2:181,745,307...181,749,364
|
|
| G
|
Rragb
|
Ras-related GTP binding B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RRAGB mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr X:21,560,313...21,610,550
Ensembl chr X:21,560,361...21,610,346
|
|
| G
|
Rragd
|
Ras-related GTP binding D
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RRAGD mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:52,170,234...52,205,700
Ensembl chr 5:52,169,783...52,209,000
|
|
| G
|
Rrbp1
|
ribosome binding protein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of RRBP1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:151,768,386...151,830,255
Ensembl chr 3:151,768,386...151,830,255
|
|
| G
|
Rrh
|
retinal pigment epithelium derived rhodopsin homolog
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of RRH mRNA trichostatin A inhibits the reaction [Nickel affects the expression of RRH mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 2:221,036,436...221,048,627
Ensembl chr 2:221,036,436...221,048,627
|
|
| G
|
Rrm2
|
ribonucleotide reductase regulatory subunit M2
|
increases expression
|
ISO
|
Nickel results in increased expression of RRM2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 6:47,044,755...47,075,370
Ensembl chr 6:47,067,690...47,075,370
|
|
| G
|
Rrp12
|
ribosomal RNA processing 12
|
increases expression
|
ISO
|
Nickel results in increased expression of RRP12 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:250,621,707...250,655,318
Ensembl chr 1:250,621,707...250,655,318
|
|
| G
|
Rrp15
|
ribosomal RNA processing 15 homolog
|
increases expression
|
ISO
|
Nickel results in increased expression of RRP15 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:100,807,729...100,830,812
Ensembl chr13:100,807,722...100,830,834
|
|
| G
|
Rrp9
|
ribosomal RNA processing 9, U3 small nucleolar RNA binding protein
|
increases expression
|
ISO
|
Nickel results in increased expression of RRP9 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 8:115,995,119...116,004,832
Ensembl chr 8:115,996,169...116,004,824
|
|
| G
|
Rsad2
|
radical S-adenosyl methionine domain containing 2
|
increases expression
|
ISO
|
Nickel results in increased expression of RSAD2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:48,774,985...48,788,245
Ensembl chr 6:48,774,985...48,788,320
|
|
| G
|
Rsbn1l
|
round spermatid basic protein 1-like
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RSBN1L mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 4:15,014,405...15,093,287
Ensembl chr 4:15,031,173...15,093,286
|
|
| G
|
Rsf1
|
remodeling and spacing factor 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RSF1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:161,303,596...161,426,326
Ensembl chr 1:161,303,660...161,420,290
|
|
| G
|
Rsph1
|
radial spoke head component 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RSPH1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr20:9,343,258...9,361,988
Ensembl chr20:9,343,261...9,361,988
|
|
| G
|
Rspo1
|
R-spondin 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RSPO1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:142,536,162...142,557,611
Ensembl chr 5:142,536,344...142,557,776
|
|
| G
|
Rspo3
|
R-spondin 3
|
increases expression
|
ISO
|
Nickel results in increased expression of RSPO3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:30,112,529...30,197,267
Ensembl chr 1:30,112,114...30,197,938
|
|
| G
|
Rsu1
|
Ras suppressor protein 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RSU1 mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr17:81,037,848...81,286,127
Ensembl chr17:81,042,595...81,286,030
|
|
| G
|
RT1-Bb
|
RT1 class II, locus Bb
|
increases expression
|
ISO
|
Nickel results in increased expression of HLA-DQB1 mRNA
|
CTD |
PMID:23195993 PMID:24768652 |
|
NCBI chr20:4,598,475...4,604,118
Ensembl chr20:4,598,475...4,604,118
|
|
| G
|
RT1-Da
|
RT1 class II, locus Da
|
increases expression
|
ISO
|
Nickel results in increased expression of HLA-DRA mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr20:4,515,393...4,520,387
Ensembl chr20:4,513,908...4,520,383
|
|
| G
|
RT1-Db1
|
RT1 class II, locus Db1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of H2-EB1 mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr20:4,550,594...4,560,182
Ensembl chr20:4,550,596...4,560,165
|
|
| G
|
RT1-DMb
|
RT1 class II, locus DMb
|
increases expression
|
ISO
|
Nickel results in increased expression of HLA-DMB mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr20:4,695,009...4,702,560
Ensembl chr20:4,695,010...4,702,246
|
|
| G
|
RT1-DOb
|
RT1 class II, locus DOb
|
increases expression
|
ISO
|
Nickel results in increased expression of HLA-DOB mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr20:4,621,336...4,627,537
Ensembl chr20:4,619,694...4,627,523
|
|
| G
|
RT1-Ha
|
RT1 class II, locus Ha
|
increases expression
|
ISO
|
Nickel results in increased expression of HLA-DPA1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr20:4,762,425...4,772,439
Ensembl chr20:4,763,033...4,772,141
|
|
| G
|
Rtkn2
|
rhotekin 2
|
increases expression
|
ISO
|
Nickel results in increased expression of RTKN2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr20:20,535,553...20,608,863
Ensembl chr20:20,535,553...20,608,899
|
|
| G
|
Rtn2
|
reticulon 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RTN2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:88,063,124...88,076,082
Ensembl chr 1:88,063,119...88,076,043
|
|
| G
|
Rtp4
|
receptor (chemosensory) transporter protein 4
|
increases expression
|
ISO
|
Nickel results in increased expression of RTP4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr11:90,741,992...90,840,061
Ensembl chr11:90,741,992...90,753,851
|
|
| G
|
Rubcnl
|
rubicon like autophagy enhancer
|
increases expression
|
ISO
|
Nickel results in increased expression of RUBCNL mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr15:56,741,897...56,807,086
Ensembl chr15:56,741,869...56,779,649
|
|
| G
|
Rundc3b
|
RUN domain containing 3B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RUNDC3B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:26,417,501...26,554,404
Ensembl chr 4:26,417,437...26,554,403
|
|
| G
|
Runx1t1
|
RUNX1 partner transcriptional co-repressor 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RUNX1T1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:31,984,946...32,136,878
Ensembl chr 5:31,984,855...32,132,855
|
|
| G
|
Runx3
|
RUNX family transcription factor 3
|
increases expression
|
ISO
|
Nickel results in increased expression of RUNX3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:152,644,270...152,702,835
Ensembl chr 5:152,644,270...152,702,835
|
|
| G
|
Ruvbl1
|
RuvB-like AAA ATPase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of RUVBL1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:122,489,754...122,524,666
Ensembl chr 4:122,489,680...122,524,665
|
|
| G
|
Ryr3
|
ryanodine receptor 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of RYR3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:119,886,129...120,433,465
Ensembl chr 3:119,885,878...120,433,677
|
|
| G
|
S100a1
|
S100 calcium binding protein A1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of S100A1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:178,291,503...178,296,346
Ensembl chr 2:178,291,503...178,296,346
|
|
| G
|
S100a11
|
S100 calcium binding protein A11
|
decreases expression
|
ISO
|
Nickel results in decreased expression of S100A11 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 2:181,875,132...181,880,542
Ensembl chr 2:181,875,130...181,880,541
|
|
| G
|
S100a14
|
S100 calcium binding protein A14
|
increases expression
|
ISO
|
Nickel results in increased expression of S100A14 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:178,305,976...178,308,004
Ensembl chr 2:178,306,025...178,307,999
|
|
| G
|
S100a2
|
S100 calcium binding protein A2
|
increases expression
|
ISO
|
Nickel results in increased expression of S100A2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:178,374,659...178,375,903
|
|
| G
|
S100a6
|
S100 calcium binding protein A6
|
increases expression
|
ISO
|
Nickel results in increased expression of S100A6 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:178,398,189...178,399,763
Ensembl chr 2:178,398,481...178,399,762
|
|
| G
|
S100a7a
|
S100 calcium binding protein A7A
|
increases expression
|
ISO
|
Nickel results in increased expression of S100A7A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:178,448,983...178,453,424
Ensembl chr 2:178,448,983...178,453,424
|
|
| G
|
S100a8
|
S100 calcium binding protein A8
|
increases expression
|
ISO
|
Nickel results in increased expression of S100A8 mRNA
|
CTD |
PMID:12540486 PMID:24768652 PMID:25583101 |
|
NCBI chr 2:178,464,095...178,465,223
Ensembl chr 2:178,464,702...178,465,221
|
|
| G
|
S100a9
|
S100 calcium binding protein A9
|
increases expression
|
ISO
|
Nickel results in increased expression of S100A9 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:178,487,941...178,490,622
Ensembl chr 2:178,487,941...178,490,870
|
|
| G
|
S1pr1
|
sphingosine-1-phosphate receptor 1
|
increases expression
|
ISO
|
Nickel results in increased expression of S1PR1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 2:206,309,715...206,314,070
Ensembl chr 2:205,900,836...206,328,689
|
|
| G
|
S1pr2
|
sphingosine-1-phosphate receptor 2
|
increases expression
|
ISO
|
Nickel results in increased expression of S1PR2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:27,779,452...27,790,344
Ensembl chr 8:27,774,566...27,790,577
|
|
| G
|
S1pr3
|
sphingosine-1-phosphate receptor 3
|
increases expression
|
ISO
|
Nickel results in increased expression of S1PR3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr17:13,932,773...13,946,213
Ensembl chr17:13,928,444...13,947,197
|
|
| G
|
Sall2
|
spalt-like transcription factor 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SALL2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr15:27,494,831...27,512,402
Ensembl chr15:27,494,589...27,512,402
|
|
| G
|
Samd12
|
sterile alpha motif domain containing 12
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SAMD12 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:86,658,709...86,953,879
Ensembl chr 7:86,658,072...87,207,686
|
|
| G
|
Samd3
|
sterile alpha motif domain containing 3
|
increases expression
|
ISO
|
Nickel results in increased expression of SAMD3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:20,920,129...20,967,595
Ensembl chr 1:20,920,129...20,967,595
|
|
| G
|
Samd5
|
sterile alpha motif domain containing 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SAMD5 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:5,861,793...5,911,153
Ensembl chr 1:5,497,567...5,911,064
|
|
| G
|
Samd8
|
sterile alpha motif domain containing 8
|
increases expression
|
ISO
|
Nickel results in increased expression of SAMD8 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr15:2,561,435...2,611,702
Ensembl chr15:2,561,435...2,607,052
|
|
| G
|
Samd9
|
sterile alpha motif domain containing 9
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of SAMD9 mRNA Nickel results in increased expression of SAMD9 mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 4:32,119,318...32,139,008
Ensembl chr 4:32,117,137...32,171,759
|
|
| G
|
Samd9l
|
sterile alpha motif domain containing 9 like
|
increases expression decreases expression
|
ISO
|
Nickel results in increased expression of SAMD9L mRNA Nickel results in decreased expression of SAMD9L mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr 4:32,316,748...32,331,112
Ensembl chr 4:32,222,623...32,331,067
|
|
| G
|
Samhd1
|
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of SAMHD1 mRNA Nickel results in increased expression of SAMHD1 mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 3:166,179,742...166,214,448
Ensembl chr 3:166,181,588...166,214,410
|
|
| G
|
Samsn1
|
SAM domain, SH3 domain and nuclear localization signals, 1
|
increases expression
|
ISO
|
Nickel results in increased expression of SAMSN1 mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr11:27,971,565...28,021,944
Ensembl chr11:27,970,564...28,021,944
|
|
| G
|
Sar1a
|
secretion associated, Ras related GTPase 1A
|
increases expression
|
ISO
|
Nickel results in increased expression of SAR1A mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr20:30,166,310...30,178,718
Ensembl chr20:30,166,334...30,178,710
|
|
| G
|
Sash3
|
SAM and SH3 domain containing 3
|
increases expression
|
ISO
|
Nickel results in increased expression of SASH3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr X:132,204,717...132,219,421
Ensembl chr X:132,204,543...132,219,419
|
|
| G
|
Satb2
|
SATB homeobox 2
|
increases expression
|
ISO
|
Nickel results in increased expression of SATB2 protein
|
CTD |
PMID:26780400 |
|
NCBI chr 9:65,842,351...66,028,569
Ensembl chr 9:65,844,570...66,021,238
|
|
| G
|
Sav1
|
salvador family WW domain containing protein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of SAV1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:94,214,514...94,236,354
Ensembl chr 6:94,214,517...94,235,945
|
|
| G
|
Sbno2
|
strawberry notch homolog 2
|
increases expression
|
ISO
|
Nickel results in increased expression of SBNO2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:10,256,221...10,300,175
Ensembl chr 7:10,253,248...10,300,176
|
|
| G
|
Scarb1
|
scavenger receptor class B, member 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SCARB1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr12:36,957,302...37,023,982
Ensembl chr12:36,957,496...37,023,980
|
|
| G
|
Scg2
|
secretogranin II
|
increases expression
|
ISO
|
Nickel results in increased expression of SCG2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:88,251,531...88,257,208
Ensembl chr 9:88,251,354...88,269,598
|
|
| G
|
Scgb1d2
|
secretoglobin, family 1D, member 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SCGB1D2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:215,653,464...215,658,101
Ensembl chr 1:215,653,464...215,656,710
|
|
| G
|
Scgb2a1
|
secretoglobin, family 2A, member 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SCGB2A1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:215,922,751...215,926,114
Ensembl chr 1:215,794,572...215,797,345 Ensembl chr 1:215,794,572...215,797,345
|
|
| G
|
Scgb3a2
|
secretoglobin, family 3A, member 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SCGB3A2 mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr18:36,183,745...36,186,667
Ensembl chr18:36,183,698...36,186,742
|
|
| G
|
Scimp
|
SLP adaptor and CSK interacting membrane protein
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SCIMP mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr10:56,006,243...56,026,357
Ensembl chr10:56,006,243...56,026,357
|
|
| G
|
Scin
|
scinderin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SCIN mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 6:62,836,641...62,915,287
Ensembl chr 6:62,836,641...62,915,287
|
|
| G
|
Scml4
|
Scm polycomb group protein like 4
|
increases expression
|
ISO
|
Nickel results in increased expression of SCML4 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr20:47,929,539...48,023,419
Ensembl chr20:47,929,539...48,023,419
|
|
| G
|
Scn1a
|
sodium voltage-gated channel alpha subunit 1
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of SCN1A mRNA trichostatin A inhibits the reaction [Nickel affects the expression of SCN1A mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 3:71,360,840...71,479,870
Ensembl chr 3:71,360,841...71,479,791
|
|
| G
|
Scn3a
|
sodium voltage-gated channel alpha subunit 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SCN3A mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:70,554,496...70,666,198
Ensembl chr 3:70,556,224...70,666,198
|
|
| G
|
Scn4b
|
sodium voltage-gated channel beta subunit 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SCN4B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:54,343,873...54,359,046
Ensembl chr 8:54,334,548...54,359,047
|
|
| G
|
Scn7a
|
sodium voltage-gated channel alpha subunit 7
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SCN7A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:71,743,873...71,846,454
Ensembl chr 3:71,743,873...71,846,284
|
|
| G
|
Scn9a
|
sodium voltage-gated channel alpha subunit 9
|
increases expression
|
ISO
|
Nickel results in increased expression of SCN9A mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:71,553,185...71,701,377
Ensembl chr 3:71,553,189...71,701,377
|
|
| G
|
Scnn1b
|
sodium channel epithelial 1 subunit beta
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SCNN1B mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:185,861,326...185,915,717
Ensembl chr 1:185,854,733...185,916,049
|
|
| G
|
Scnn1g
|
sodium channel epithelial 1 subunit gamma
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SCNN1G mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:185,736,225...185,770,099
Ensembl chr 1:185,736,191...185,770,097
|
|
| G
|
Sco1
|
synthesis of cytochrome C oxidase 1
|
multiple interactions
|
ISO
|
Nickel binds to and affects the folding of SCO1 protein
|
CTD |
PMID:16735468 |
|
NCBI chr10:52,243,664...52,256,250
Ensembl chr10:52,243,648...52,260,861
|
|
| G
|
Scrg1
|
stimulator of chondrogenesis 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SCRG1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr16:37,770,739...37,799,010
Ensembl chr16:37,770,739...37,799,010
|
|
| G
|
Sctr
|
secretin receptor
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SCTR mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:33,680,562...33,744,049
Ensembl chr13:33,680,627...33,733,709
|
|
| G
|
Scube2
|
signal peptide, CUB domain and EGF like domain containing 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SCUBE2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:173,264,862...173,341,323
Ensembl chr 1:173,264,865...173,334,372
|
|
| G
|
Scube3
|
signal peptide, CUB domain and EGF like domain containing 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SCUBE3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr20:6,200,891...6,232,848
Ensembl chr20:6,200,178...6,233,051
|
|
| G
|
Scyl3
|
SCY1 like pseudokinase 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SCYL3 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr13:78,811,595...78,836,202
Ensembl chr13:78,811,741...78,836,204
|
|
| G
|
Sdad1
|
SDA1 domain containing 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SDAD1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr14:16,025,726...16,052,565
Ensembl chr14:16,025,727...16,055,359
|
|
| G
|
Sdc4
|
syndecan 4
|
increases expression
|
ISO
|
Nickel results in increased expression of SDC4 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 3:173,574,239...173,592,923
Ensembl chr 3:173,574,239...173,593,670
|
|
| G
|
Sde2
|
SDE2 telomere maintenance homolog
|
increases expression
|
ISO
|
Nickel results in increased expression of SDE2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr13:95,110,598...95,126,929
Ensembl chr13:95,110,698...95,126,927
|
|
| G
|
Sdf2l1
|
stromal cell-derived factor 2-like 1
|
increases expression
|
ISO
|
Nickel results in increased expression of SDF2L1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:97,376,878...97,379,120
Ensembl chr11:97,376,878...97,379,120
|
|
| G
|
Sdk1
|
sidekick cell adhesion molecule 1
|
increases expression
|
ISO
|
Nickel results in increased expression of SDK1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr12:17,491,430...18,477,914
Ensembl chr12:17,493,869...18,477,935
|
|
| G
|
Sdk2
|
sidekick cell adhesion molecule 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SDK2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:99,324,047...99,601,683
Ensembl chr10:99,324,047...99,601,683
|
|
| G
|
Sec16b
|
SEC16 homolog B, endoplasmic reticulum export factor
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SEC16B mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:72,206,778...72,260,733
Ensembl chr13:72,206,772...72,260,729
|
|
| G
|
Sec22c
|
SEC22 homolog C, vesicle trafficking protein
|
increases expression
|
ISO
|
Nickel results in increased expression of SEC22C mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:130,223,349...130,249,079
Ensembl chr 8:130,223,349...130,247,852
|
|
| G
|
Sec23b
|
Sec23 homolog B, COPII coat complex component
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SEC23B mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 3:152,392,340...152,434,813
Ensembl chr 3:152,392,308...152,434,800
|
|
| G
|
Sec23ip
|
SEC23 interacting protein
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SEC23IP mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 1:192,751,379...192,794,345
Ensembl chr 1:192,751,454...192,794,969
|
|
| G
|
Sec24b
|
SEC24 homolog B, COPII coat complex component
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of SEC24B mRNA trichostatin A inhibits the reaction [Nickel affects the expression of SEC24B mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 2:221,236,897...221,306,986
Ensembl chr 2:221,236,898...221,306,919
|
|
| G
|
Sec24d
|
SEC24 homolog D, COPII coat complex component
|
increases expression
|
ISO
|
Nickel results in increased expression of SEC24D mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:214,103,138...214,211,155
Ensembl chr 2:214,103,190...214,211,144
|
|
| G
|
Sec61a1
|
SEC61 translocon subunit alpha 1
|
increases expression
|
ISO
|
Nickel results in increased expression of SEC61A1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:122,530,785...122,545,141
Ensembl chr 4:122,530,789...122,545,141
|
|
| G
|
Sectm1b
|
secreted and transmembrane 1B
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of SECTM1 mRNA Nickel results in increased expression of SECTM1 mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr10:106,822,397...106,832,105
Ensembl chr10:106,822,397...106,832,104
|
|
| G
|
Seh1l
|
SEH1-like nucleoporin
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of SEH1L mRNA Nickel results in increased expression of SEH1L mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr18:63,612,228...63,639,852
Ensembl chr18:63,616,768...63,639,840
|
|
| G
|
Sel1l
|
SEL1L adaptor subunit of SYVN1 ubiquitin ligase
|
increases expression
|
ISO
|
Nickel results in increased expression of SEL1L mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:116,466,163...116,510,436
Ensembl chr 6:116,466,163...116,510,578
|
|
| G
|
Sel1l3
|
SEL1L family member 3
|
increases expression
|
ISO
|
Nickel results in increased expression of SEL1L3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:61,988,350...62,095,542
Ensembl chr14:61,988,346...62,095,542
|
|
| G
|
Sele
|
selectin E
|
increases expression
|
ISO
|
Nickel results in increased expression of SELE mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:78,935,997...78,945,905
Ensembl chr13:78,936,036...78,945,903
|
|
| G
|
Selenbp1
|
selenium binding protein 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SELENBP1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:185,183,022...185,193,612
Ensembl chr 2:185,183,004...185,194,295
|
|
| G
|
Selenoi
|
selenoprotein I
|
increases expression
|
ISO
|
Nickel results in increased expression of SELENOI mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 6:31,792,972...31,831,170
Ensembl chr 6:31,792,973...31,831,523
|
|
| G
|
Selenok
|
selenoprotein K
|
increases expression
|
ISO
|
Nickel results in increased expression of SELENOK mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr16:5,158,601...5,167,183
Ensembl chr16:5,158,621...5,168,512
|
|
| G
|
Selenom
|
selenoprotein M
|
affects response to substance multiple interactions
|
ISO
|
SELENOM protein affects the susceptibility to Nickel [SELENOM protein affects the susceptibility to Nickel] which affects the expression of CASP1 mRNA; [SELENOM protein affects the susceptibility to Nickel] which affects the expression of CASP1 protein; [SELENOM protein affects the susceptibility to Nickel] which affects the expression of CYBB mRNA; [SELENOM protein affects the susceptibility to Nickel] which affects the expression of IL18 mRNA; [SELENOM protein affects the susceptibility to Nickel] which affects the expression of IL1B mRNA; [SELENOM protein affects the susceptibility to Nickel] which affects the expression of NLRP3 mRNA; [SELENOM protein affects the susceptibility to Nickel] which affects the expression of NLRP3 protein; [SELENOM protein affects the susceptibility to Nickel] which affects the expression of PYCARD mRNA; [SELENOM protein affects the susceptibility to Nickel] which affects the expression of PYCARD protein; [SELENOM protein affects the susceptibility to Nickel] which affects the expression of TXN1 mRNA; Melatonin affects the reaction [[SELENOM protein affects the susceptibility to Nickel] which affects the expression of CASP1 mRNA]; Melatonin affects the reaction [[SELENOM protein affects the susceptibility to Nickel] which affects the expression of CASP1 protein]; Melatonin affects the reaction [[SELENOM protein affects the susceptibility to Nickel] which affects the expression of CYBB mRNA]; Melatonin affects the reaction [[SELENOM protein affects the susceptibility to Nickel] which affects the expression of IL18 mRNA]; Melatonin affects the reaction [[SELENOM protein affects the susceptibility to Nickel] which affects the expression of IL1B mRNA]; Melatonin affects the reaction [[SELENOM protein affects the susceptibility to Nickel] which affects the expression of NLRP3 mRNA]; Melatonin affects the reaction [[SELENOM protein affects the susceptibility to Nickel] which affects the expression of NLRP3 protein]; Melatonin affects the reaction [[SELENOM protein affects the susceptibility to Nickel] which affects the expression of PYCARD mRNA]; Melatonin affects the reaction [[SELENOM protein affects the susceptibility to Nickel] which affects the expression of PYCARD protein]; Melatonin affects the reaction [Nickel affects the reaction [SELENOM protein affects the expression of AIM2 mRNA]]; Melatonin affects the reaction [Nickel affects the reaction [SELENOM protein affects the expression of IL1B protein]]; Melatonin affects the reaction [Nickel affects the reaction [SELENOM protein affects the expression of TXNIP mRNA]]; Melatonin inhibits the reaction [SELENOM protein affects the susceptibility to Nickel]; Nickel affects the reaction [Melatonin affects the reaction [SELENOM protein affects the expression of AIM2 mRNA]]; Nickel affects the reaction [Melatonin affects the reaction [SELENOM protein affects the expression of IL1B protein]]; Nickel affects the reaction [SELENOM protein affects the expression of AIM2 mRNA]; Nickel affects the reaction [SELENOM protein affects the expression of IL1B protein]; Nickel affects the reaction [SELENOM protein affects the expression of TXNIP mRNA]
|
CTD |
PMID:36504304 |
|
NCBI chr14:82,619,453...82,622,056
Ensembl chr14:82,619,436...82,622,054
|
|
| G
|
Selenop
|
selenoprotein P
|
affects binding decreases expression
|
ISO
|
SELENOP protein binds to Nickel Nickel results in decreased expression of SELENOP mRNA
|
CTD |
PMID:23896426 PMID:24768652 PMID:25583101 |
|
NCBI chr 2:54,225,736...54,236,022
Ensembl chr 2:54,225,152...54,236,019
|
|
| G
|
Sell
|
selectin L
|
increases expression
|
ISO
|
Nickel results in increased expression of SELL mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:78,950,100...78,969,604
Ensembl chr13:78,950,015...78,969,600
|
|
| G
|
Selp
|
selectin P
|
affects expression increases expression multiple interactions
|
ISO
|
Nickel affects the expression of SELP mRNA Nickel results in increased expression of SELP mRNA trichostatin A inhibits the reaction [Nickel affects the expression of SELP mRNA]
|
CTD |
PMID:14575637 PMID:25583101 |
|
NCBI chr13:79,009,379...79,044,994
Ensembl chr13:79,009,475...79,044,987
|
|
| G
|
Selplg
|
selectin P ligand
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of SELPLG mRNA Nickel results in increased expression of SELPLG mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr12:48,457,102...48,470,444
Ensembl chr12:48,456,932...48,473,154
|
|
| G
|
Sema3b
|
semaphorin 3B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SEMA3B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:117,150,307...117,161,570
Ensembl chr 8:117,150,589...117,157,658
|
|
| G
|
Sema3e
|
semaphorin 3E
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SEMA3E mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:21,252,686...21,510,449
Ensembl chr 4:21,210,734...21,510,374
|
|
| G
|
Sema3g
|
semaphorin 3G
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SEMA3G mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr16:6,420,025...6,431,655
Ensembl chr16:6,420,012...6,432,553
|
|
| G
|
Sema4d
|
semaphorin 4D
|
increases expression
|
ISO
|
Nickel results in increased expression of SEMA4D mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr17:13,582,085...13,688,889
Ensembl chr17:13,582,098...13,688,891
|
|
| G
|
Sema4g
|
semaphorin 4G
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SEMA4G mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:253,799,552...253,814,504
Ensembl chr 1:253,800,099...253,814,503
|
|
| G
|
Sema5a
|
semaphorin 5A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SEMA5A mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:85,020,724...85,451,938
Ensembl chr 2:85,020,724...85,451,938
|
|
| G
|
Sema6d
|
semaphorin 6D
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SEMA6D mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:131,801,680...132,394,578
Ensembl chr 3:132,337,343...132,394,584
|
|
| G
|
Sepsecs
|
Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
|
increases expression
|
ISO
|
Nickel results in increased expression of SEPSECS mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr14:62,524,287...62,554,529
Ensembl chr14:62,524,313...62,554,533
|
|
| G
|
Septin1
|
septin 1
|
increases expression
|
ISO
|
Nickel results in increased expression of SEPTIN1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:191,263,200...191,267,086
Ensembl chr 1:191,263,201...191,267,066
|
|
| G
|
Septin4
|
septin 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SEPTIN4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:72,863,969...72,888,018
Ensembl chr10:72,864,014...72,888,019
|
|
| G
|
Septin5
|
septin 5
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of SEPTIN5 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of SEPTIN5 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr11:95,877,946...95,883,738
Ensembl chr11:95,873,864...95,883,737
|
|
| G
|
Septin6
|
septin 6
|
increases expression
|
ISO
|
Nickel results in increased expression of SEPTIN6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:121,018,951...121,157,677
Ensembl chr X:121,018,944...121,095,792
|
|
| G
|
Septin8
|
septin 8
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SEPTIN8 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:38,185,454...38,214,502
Ensembl chr10:38,185,335...38,214,504
|
|
| G
|
Serhl2
|
serine hydrolase-like 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SERHL2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:116,126,085...116,146,345
Ensembl chr 7:116,126,085...116,152,765
|
|
| G
|
Serp1
|
stress-associated endoplasmic reticulum protein 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SERP1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:144,907,204...144,911,187
Ensembl chr 2:144,907,205...144,911,187
|
|
| G
|
Serpina1
|
serpin family A member 1
|
affects binding increases expression
|
ISO
|
Nickel binds to SERPINA1 protein modified form; SERPINA1 protein binds to Nickel Nickel results in increased expression of SERPINA1 mRNA
|
CTD |
PMID:23896426 PMID:25579632 PMID:25583101 |
|
NCBI chr 6:128,631,101...128,653,125
Ensembl chr 6:128,619,382...128,660,703
|
|
| G
|
Serpina3n
|
serpin family A member 3N
|
affects binding increases expression
|
ISO
|
SERPINA3 protein binds to Nickel Nickel results in increased expression of SERPINA3 mRNA
|
CTD |
PMID:23896426 PMID:24768652 PMID:25583101 |
|
NCBI chr 6:129,088,392...129,095,950
Ensembl chr 6:129,088,398...129,097,415
|
|
| G
|
Serpina4
|
serpin family A member 4
|
affects binding
|
ISO
|
SERPINA4 protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr 6:128,764,738...128,773,858
Ensembl chr 6:128,764,769...128,776,028
|
|
| G
|
Serpina5
|
serpin family A member 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SERPINA5 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 6:128,774,006...128,793,187
Ensembl chr 6:128,784,991...128,793,186
|
|
| G
|
Serpina6
|
serpin family A member 6
|
affects binding
|
ISO
|
SERPINA6 protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr 6:128,544,828...128,555,064
Ensembl chr 6:128,544,831...128,555,139
|
|
| G
|
Serpina7
|
serpin family A member 7
|
affects binding
|
ISO
|
SERPINA7 protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr X:107,452,044...107,510,958
Ensembl chr X:107,452,044...107,457,681
|
|
| G
|
Serpinb13
|
serpin family B member 13
|
increases expression
|
ISO
|
Nickel results in increased expression of SERPINB13 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:23,633,220...23,665,100
Ensembl chr13:23,633,220...23,664,994
|
|
| G
|
Serpinb1a
|
serpin family B member 1A
|
increases expression
|
ISO
|
Nickel results in increased expression of SERPINB1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr17:31,799,446...31,807,853
Ensembl chr17:31,799,415...31,808,166
|
|
| G
|
Serpinb2
|
serpin family B member 2
|
increases expression
|
ISO
|
Nickel results in increased expression of SERPINB2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr13:24,051,933...24,065,032
Ensembl chr13:24,056,021...24,065,031
|
|
| G
|
Serpinb3
|
serpin family B member 3
|
increases expression
|
ISO
|
Nickel results in increased expression of SERPINB3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:23,788,758...23,795,298
Ensembl chr13:23,788,758...23,795,298
|
|
| G
|
Serpinb3a
|
serpin family B member 3A
|
increases expression
|
ISO
|
Nickel results in increased expression of SERPINB4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:23,755,690...23,766,188
Ensembl chr13:23,756,118...23,766,341
|
|
| G
|
Serpinb9
|
serpin family B member 9
|
increases expression
|
ISO
|
Nickel results in increased expression of SERPINB9 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr17:31,628,887...31,652,003
Ensembl chr17:31,629,392...31,651,974
|
|
| G
|
Serpinc1
|
serpin family C member 1
|
affects binding
|
ISO
|
SERPINC1 protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr13:75,790,558...75,804,826
Ensembl chr13:75,790,546...75,817,643
|
|
| G
|
Serpind1
|
serpin family D member 1
|
increases expression affects binding
|
ISO
|
Nickel results in increased expression of SERPIND1 mRNA SERPIND1 protein binds to Nickel
|
CTD |
PMID:12540486 PMID:23896426 |
|
NCBI chr11:97,168,753...97,179,830
Ensembl chr11:97,168,754...97,179,755
|
|
| G
|
Serpine1
|
serpin family E member 1
|
multiple interactions increases expression decreases stability
|
ISO
|
HIF1A protein promotes the reaction [Nickel results in increased expression of SERPINE1 mRNA]; Magnesium Chloride affects the reaction [Nickel binds to SERPINE1 protein]; Nickel binds to and results in decreased stability of SERPINE1 protein; U 0126 inhibits the reaction [Nickel results in increased expression of SERPINE1 mRNA]; VTN protein inhibits the reaction [Nickel results in decreased stability of SERPINE1 protein]
|
CTD |
PMID:11504687 PMID:21280127 PMID:21280128 PMID:24768652 PMID:25583101 |
|
NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357
|
|
| G
|
Serpine2
|
serpin family E member 2
|
increases expression
|
ISO
|
Nickel results in increased expression of SERPINE2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:88,573,138...88,637,252
Ensembl chr 9:88,573,149...88,637,202
|
|
| G
|
Serpinf2
|
serpin family F member 2
|
affects binding
|
ISO
|
SERPINF2 protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr10:60,770,698...60,778,782
Ensembl chr10:60,770,698...60,778,996
|
|
| G
|
Serping1
|
serpin family G member 1
|
affects binding
|
ISO
|
SERPING1 protein binds to Nickel
|
CTD |
PMID:23896426 |
|
NCBI chr 3:90,249,410...90,259,299
Ensembl chr 3:90,249,423...90,258,717
|
|
| G
|
Serpinh1
|
serpin family H member 1
|
increases expression
|
ISO
|
Nickel results in increased expression of SERPINH1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:163,055,630...163,063,177
Ensembl chr 1:163,055,630...163,062,976
|
|
| G
|
Serpini1
|
serpin family I member 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SERPINI1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:162,645,209...162,731,737
Ensembl chr 2:162,645,350...162,731,740
|
|
| G
|
Sertad1
|
SERTA domain containing 1
|
increases expression
|
ISO
|
Nickel results in increased expression of SERTAD1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:91,903,297...91,906,565
Ensembl chr 1:91,891,814...91,907,001
|
|
| G
|
Sertad4
|
SERTA domain containing 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SERTAD4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:106,889,019...106,899,777
Ensembl chr13:106,889,019...106,900,309
|
|
| G
|
Sertm1
|
serine-rich and transmembrane domain containing 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SERTM1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 2:141,237,054...141,256,669
Ensembl chr 2:141,235,409...141,265,984
|
|
| G
|
Sesn1
|
sestrin 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SESN1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr20:46,876,918...46,970,010
Ensembl chr20:46,876,895...46,970,010
|
|
| G
|
Sestd1
|
SEC14 and spectrin domain containing 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SESTD1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:82,530,796...82,627,960
Ensembl chr 3:82,537,092...82,588,078
|
|
| G
|
Setd7
|
SET domain containing 7, histone lysine methyltransferase
|
increases expression
|
ISO
|
Nickel results in increased expression of SETD7 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:137,713,545...137,756,319
Ensembl chr 2:137,713,545...137,756,319
|
|
| G
|
Setx
|
senataxin
|
increases expression
|
ISO
|
Nickel results in increased expression of SETX mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 3:32,825,771...32,878,740
Ensembl chr 3:32,828,412...32,878,740
|
|
| G
|
Sez6l
|
seizure related 6 homolog like
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SEZ6L mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr12:49,725,330...49,882,222
Ensembl chr12:49,725,330...49,882,222
|
|
| G
|
Sf3b3
|
splicing factor 3b, subunit 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SF3B3 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr19:55,692,124...55,729,640
Ensembl chr19:55,692,126...55,729,621
|
|
| G
|
Sfmbt2
|
Scm-like with four mbt domains 2
|
increases expression
|
ISO
|
Nickel results in increased expression of SFMBT2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr17:72,844,037...73,038,599
Ensembl chr17:72,845,708...73,032,172
|
|
| G
|
Sfn
|
stratifin
|
increases expression
|
ISO
|
Nickel results in increased expression of SFN mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:151,110,582...151,111,854
Ensembl chr 5:151,110,530...151,111,995
|
|
| G
|
Sfpq
|
splicing factor proline and glutamine rich
|
affects expression increases expression multiple interactions
|
ISO
|
Nickel affects the expression of SFPQ mRNA Nickel results in increased expression of SFPQ mRNA trichostatin A inhibits the reaction [Nickel affects the expression of SFPQ mRNA]
|
CTD |
PMID:14575637 PMID:24768652 PMID:25583101 |
|
NCBI chr 5:144,621,678...144,637,930
Ensembl chr 5:144,622,476...144,637,926
|
|
| G
|
Sfrp1
|
secreted frizzled-related protein 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SFRP1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr16:75,278,325...75,316,736
Ensembl chr16:75,278,325...75,316,736
|
|
| G
|
Sfrp4
|
secreted frizzled-related protein 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SFRP4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr17:49,974,532...50,026,448
Ensembl chr17:50,015,812...50,026,395
|
|
| G
|
Sft2d1
|
SFT2 domain containing 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SFT2D1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 1:54,957,247...54,973,143
Ensembl chr 1:54,960,692...54,973,143
|
|
| G
|
Sft2d2
|
SFT2 domain containing 2
|
increases expression
|
ISO
|
Nickel results in increased expression of SFT2D2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr13:80,017,854...80,037,144
Ensembl chr13:80,008,480...80,037,473
|
|
| G
|
Sftpa1
|
surfactant protein A1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SFTPA1 mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr16:17,042,264...17,045,770
Ensembl chr16:17,042,255...17,045,769
|
|
| G
|
Sftpb
|
surfactant protein B
|
multiple interactions decreases expression
|
ISO
|
SFTPB protein affects the reaction [Nickel results in decreased expression of MT1 mRNA]; SFTPB protein affects the reaction [Nickel results in decreased expression of MT2 mRNA] Nickel results in decreased expression of SFTPB mRNA
|
CTD |
PMID:12540486 PMID:16166738 |
|
NCBI chr 4:105,917,495...105,926,631
Ensembl chr 4:105,917,578...105,927,646
|
|
| G
|
Sftpc
|
surfactant protein C
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SFTPC mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr15:52,006,274...52,009,324
Ensembl chr15:52,006,283...52,009,475
|
|
| G
|
Sgcd
|
sarcoglycan, delta
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SGCD mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:31,847,713...32,829,554
Ensembl chr10:31,781,748...32,419,064
|
|
| G
|
Sgcg
|
sarcoglycan, gamma
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SGCG mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr15:39,564,920...39,611,149
Ensembl chr15:39,564,923...39,611,149
|
|
| G
|
Sgk2
|
serum/glucocorticoid regulated kinase 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SGK2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:172,063,625...172,089,000
Ensembl chr 3:172,063,776...172,089,011
|
|
| G
|
Sgms2
|
sphingomyelin synthase 2
|
increases expression
|
ISO
|
Nickel results in increased expression of SGMS2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:222,567,661...222,641,804
Ensembl chr 2:222,567,664...222,590,807
|
|
| G
|
Sgsm1
|
small G protein signaling modulator 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SGSM1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr12:48,969,578...49,049,110
Ensembl chr12:48,981,693...49,046,921
|
|
| G
|
Sh2b3
|
SH2B adaptor protein 3
|
increases expression
|
ISO
|
Nickel results in increased expression of SH2B3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr12:40,391,755...40,414,336
Ensembl chr12:40,392,633...40,414,335
|
|
| G
|
Sh2d1a
|
SH2 domain containing 1A
|
increases expression
|
ISO
|
Nickel results in increased expression of SH2D1A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:126,239,191...126,267,425
Ensembl chr X:126,239,200...126,267,424
|
|
| G
|
Sh2d1b
|
SH2 domain containing 1B
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SH2D1B mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr13:85,018,078...85,056,263
Ensembl chr13:85,019,508...85,052,125
|
|
| G
|
Sh2d2a
|
SH2 domain containing 2A
|
increases expression
|
ISO
|
Nickel results in increased expression of SH2D2A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:175,610,127...175,616,685
Ensembl chr 2:175,609,874...175,616,685
|
|
| G
|
Sh2d3c
|
SH2 domain containing 3C
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SH2D3C mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 3:36,408,305...36,444,191
Ensembl chr 3:36,408,304...36,444,716
|
|
| G
|
Sh3bgr
|
SH3 domain binding glutamate-rich protein
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SH3BGR mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:48,973,033...48,997,328
Ensembl chr11:48,973,097...48,997,326
|
|
| G
|
Sh3bgrl2
|
SH3 domain binding glutamate-rich protein like 2
|
increases expression decreases expression
|
ISO
|
Nickel results in increased expression of SH3BGRL2 mRNA Nickel results in decreased expression of SH3BGRL2 mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr 8:93,341,104...93,433,143
Ensembl chr 8:93,341,149...93,433,143
|
|
| G
|
Sh3bgrl3
|
SH3 domain binding glutamate-rich protein like 3
|
increases expression
|
ISO
|
Nickel results in increased expression of SH3BGRL3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:151,637,897...151,639,270
Ensembl chr 5:151,637,674...151,639,395
|
|
| G
|
Sh3tc1
|
SH3 domain and tetratricopeptide repeats 1
|
increases expression
|
ISO
|
Nickel results in increased expression of SH3TC1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:79,230,322...79,274,622
Ensembl chr14:79,230,371...79,274,620
|
|
| G
|
Shank2
|
SH3 and multiple ankyrin repeat domains 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SHANK2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:208,575,144...209,020,300
Ensembl chr 1:208,598,772...209,018,736
|
|
| G
|
Shc1
|
SHC adaptor protein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of SHC1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:177,135,649...177,147,257
Ensembl chr 2:177,135,659...177,147,914
|
|
| G
|
Shc3
|
SHC adaptor protein 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SHC3 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr17:13,803,980...13,924,433
Ensembl chr17:13,803,781...13,924,433
|
|
| G
|
Shc4
|
SHC adaptor protein 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SHC4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:133,334,026...133,428,404
Ensembl chr 3:133,334,034...133,427,826
|
|
| G
|
Shfl
|
shiftless antiviral inhibitor of ribosomal frameshifting
|
increases expression
|
ISO
|
Nickel results in increased expression of SHFL mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 8:27,683,560...27,690,269
Ensembl chr 8:27,684,510...27,690,679
|
|
| G
|
Shisa3
|
shisa family member 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SHISA3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr14:40,917,563...40,922,135
Ensembl chr14:40,917,564...40,922,135
|
|
| G
|
Shisal1
|
shisa like 1
|
increases expression
|
ISO
|
Nickel results in increased expression of SHISAL1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:117,388,210...117,491,539
|
|
| G
|
Shmt1
|
serine hydroxymethyltransferase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SHMT1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:45,968,959...45,990,341
Ensembl chr10:45,960,434...45,997,326
|
|
| G
|
Shroom3
|
shroom family member 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SHROOM3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:15,383,769...15,681,158
Ensembl chr14:15,383,769...15,680,462
|
|
| G
|
Shroom4
|
shroom family member 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SHROOM4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr X:18,537,371...18,748,665
Ensembl chr X:18,540,913...18,748,700
|
|
| G
|
Sidt1
|
SID1 transmembrane family, member 1
|
increases expression
|
ISO
|
Nickel results in increased expression of SIDT1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:69,867,758...69,965,377
Ensembl chr11:69,868,795...69,965,519
|
|
| G
|
Siglec1
|
sialic acid binding Ig like lectin 1
|
increases expression
|
ISO
|
Nickel results in increased expression of SIGLEC1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:138,740,171...138,759,966
Ensembl chr 3:138,741,019...138,759,881
|
|
| G
|
Siglec10
|
sialic acid binding Ig-like lectin 10
|
increases expression
|
ISO
|
Nickel results in increased expression of SIGLEC10 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:102,953,894...102,962,964
Ensembl chr 1:102,953,918...102,962,964
|
|
| G
|
Siglec5
|
sialic acid binding Ig-like lectin 5
|
increases expression
|
ISO
|
Nickel results in increased expression of SIGLEC6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:102,904,705...102,913,281
Ensembl chr 1:102,904,578...102,913,281
|
|
| G
|
Sik1
|
salt-inducible kinase 1
|
increases expression multiple interactions
|
ISO EXP
|
Nickel results in increased expression of SIK1 mRNA [nickel sulfate results in increased abundance of Nickel] which results in increased expression of SIK1 mRNA
|
CTD |
PMID:23195993 PMID:31734292 |
|
NCBI chr20:9,947,104...9,958,729
Ensembl chr20:9,947,105...9,958,698
|
|
| G
|
Sik2
|
salt-inducible kinase 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SIK2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 8:60,121,913...60,221,707
Ensembl chr 8:60,121,913...60,221,818
|
|
| G
|
Sim1
|
SIM bHLH transcription factor 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SIM1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr20:55,409,814...55,489,450
Ensembl chr20:55,410,577...55,489,449
|
|
| G
|
Sim2
|
SIM bHLH transcription factor 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SIM2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:46,883,859...46,923,305
Ensembl chr11:46,883,859...46,923,305
|
|
| G
|
Sipa1l1
|
signal-induced proliferation-associated 1 like 1
|
increases expression
|
ISO
|
Nickel results in increased expression of SIPA1L1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 6:107,570,569...107,849,613
Ensembl chr 6:107,737,392...107,848,160
|
|
| G
|
Sirpa
|
signal-regulatory protein alpha
|
increases expression
|
ISO
|
Nickel results in increased expression of SIRPA mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:137,272,932...137,311,279
Ensembl chr 3:137,273,042...137,311,279
|
|
| G
|
Sit1
|
signaling threshold regulating transmembrane adaptor 1
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of SIT1 mRNA Nickel results in increased expression of SIT1 mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr 5:62,536,003...62,538,230
Ensembl chr 5:62,536,009...62,537,911
|
|
| G
|
Skap1
|
src kinase associated phosphoprotein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of SKAP1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:81,921,961...82,229,106
Ensembl chr10:81,921,980...82,229,105
|
|
| G
|
Skida1
|
SKI/DACH domain containing 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SKIDA1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr17:85,706,693...85,717,499
Ensembl chr17:85,707,366...85,716,576
|
|
| G
|
Skp2
|
S-phase kinase associated protein 2
|
multiple interactions
|
ISO
|
MT1 affects the reaction [Nickel affects the expression of SKP2 mRNA]; MT2 affects the reaction [Nickel affects the expression of SKP2 mRNA]
|
CTD |
PMID:16166738 |
|
NCBI chr 2:59,888,406...59,916,471
Ensembl chr 2:59,888,413...59,916,438
|
|
| G
|
Sla
|
src-like adaptor
|
increases expression
|
ISO
|
Nickel results in increased expression of SLA mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:100,423,467...100,473,840
Ensembl chr 7:100,424,169...100,473,684
|
|
| G
|
Sla2
|
Src-like-adaptor 2
|
increases expression
|
ISO
|
Nickel results in increased expression of SLA2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:165,821,164...165,848,087
Ensembl chr 3:165,828,657...165,847,062
|
|
| G
|
Slamf1
|
signaling lymphocytic activation molecule family member 1
|
increases expression
|
ISO
|
Nickel results in increased expression of SLAMF1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:86,802,708...86,837,890
Ensembl chr13:86,802,708...86,837,890
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Slamf6
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SLAM family member 6
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decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of SLAMF6 mRNA Nickel results in increased expression of SLAMF6 mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr13:86,916,956...86,937,697
Ensembl chr13:86,916,122...86,938,354
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| G
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Slamf7
|
SLAM family member 7
|
decreases expression increases expression
|
ISO
|
Nickel results in decreased expression of SLAMF7 mRNA Nickel results in increased expression of SLAMF7 mRNA
|
CTD |
PMID:23195993 PMID:24768652 PMID:25583101 |
|
NCBI chr13:86,668,060...86,688,222
Ensembl chr13:86,668,060...86,686,341
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| G
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Slamf8
|
SLAM family member 8
|
increases expression
|
ISO
|
Nickel results in increased expression of SLAMF8 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:87,580,081...87,589,941
Ensembl chr13:87,580,182...87,589,560
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| G
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Slc11a2
|
solute carrier family 11 member 2
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increases transport
|
ISO
|
SLC11A2 protein results in increased transport of Nickel
|
CTD |
PMID:22736759 |
|
NCBI chr 7:133,381,878...133,429,921
Ensembl chr 7:133,381,878...133,418,941
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| G
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Slc12a2
|
solute carrier family 12 member 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLC12A2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr18:53,546,263...53,614,478
Ensembl chr18:53,546,333...53,614,470
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| G
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Slc12a8
|
solute carrier family 12, member 8
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC12A8 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr11:80,622,000...80,771,674
Ensembl chr11:80,622,000...80,771,659
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| G
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Slc12a9
|
solute carrier family 12, member 9
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC12A9 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr12:25,005,741...25,022,628
Ensembl chr12:25,005,738...25,022,607
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| G
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Slc13a2
|
solute carrier family 13 member 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLC13A2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:63,789,874...63,817,441
Ensembl chr10:63,789,876...63,817,184
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| G
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Slc14a1
|
solute carrier family 14 member 1 (Kidd blood group)
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLC14A1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr18:73,840,568...73,883,925
Ensembl chr18:73,840,569...73,870,489
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| G
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Slc15a3
|
solute carrier family 15 member 3
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC15A3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:216,906,836...216,932,046
Ensembl chr 1:216,916,675...216,932,045
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| G
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Slc16a1
|
solute carrier family 16 member 1
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC16A1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 2:194,805,556...194,832,966
Ensembl chr 2:194,812,502...194,832,977
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| G
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Slc16a10
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solute carrier family 16 member 10
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLC16A10 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr20:45,014,229...45,122,392
Ensembl chr20:45,014,235...45,122,358
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| G
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Slc16a3
|
solute carrier family 16 member 3
|
increases expression multiple interactions
|
ISO
|
Nickel results in increased expression of SLC16A3 mRNA Celecoxib inhibits the reaction [Nickel results in increased expression of SLC16A3 mRNA]; Dexamethasone inhibits the reaction [Nickel results in increased expression of SLC16A3 mRNA]; Indomethacin inhibits the reaction [Nickel results in increased expression of SLC16A3 mRNA]
|
CTD |
PMID:24768652 PMID:25583101 PMID:27452194 |
|
NCBI chr10:106,712,328...106,756,168
Ensembl chr10:106,714,466...106,720,903
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| G
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Slc16a6
|
solute carrier family 16, member 6
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC16A6 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:94,923,888...94,946,990
Ensembl chr10:94,923,888...94,947,965
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| G
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Slc18a1
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solute carrier family 18 member A1
|
increases expression
|
EXP
|
Nickel results in increased expression of SLC18A1 mRNA
|
CTD |
PMID:18812211 PMID:18835401 |
|
NCBI chr16:25,408,485...25,453,786
Ensembl chr16:25,420,243...25,453,786
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| G
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Slc18a3
|
solute carrier family 18 member A3
|
decreases expression
|
EXP
|
Nickel results in decreased expression of SLC18A3 mRNA
|
CTD |
PMID:18812211 |
|
NCBI chr16:7,719,953...7,722,814
|
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| G
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Slc19a3
|
solute carrier family 19 member 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLC19A3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 9:91,723,799...91,747,499
Ensembl chr 9:91,724,718...91,754,991
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| G
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Slc1a5
|
solute carrier family 1 member 5
|
multiple interactions
|
ISO
|
[Nickel co-treated with NGF protein] results in increased expression of SLC1A5 mRNA
|
CTD |
PMID:20600679 |
|
NCBI chr 1:86,584,949...86,599,052
Ensembl chr 1:86,584,949...86,599,054
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| G
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Slc20a1
|
solute carrier family 20 member 1
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC20A1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 3:136,880,360...136,894,255
Ensembl chr 3:136,880,290...136,894,249
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| G
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Slc22a15
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solute carrier family 22, member 15
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLC22A15 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:191,987,409...192,049,859
Ensembl chr 2:191,987,409...192,047,362
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| G
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Slc25a11
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solute carrier family 25 member 11
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLC25A11 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr10:55,856,209...55,859,060
Ensembl chr10:55,855,979...55,859,060
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| G
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Slc25a15
|
solute carrier family 25 member 15
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC25A15 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr16:76,334,037...76,357,325
Ensembl chr16:76,324,288...76,357,321
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| G
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Slc25a18
|
solute carrier family 25 member 18
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLC25A18 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:155,672,939...155,693,549
Ensembl chr 4:155,673,169...155,693,548
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| G
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Slc25a19
|
solute carrier family 25 member 19
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC25A19 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:101,353,426...101,366,551
Ensembl chr10:101,350,106...101,366,351
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| G
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Slc25a20
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solute carrier family 25 member 20
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLC25A20 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 8:118,243,573...118,265,027
Ensembl chr 8:118,243,519...118,265,027
|
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| G
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Slc25a22
|
solute carrier family 25 member 22
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC25A22 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:205,954,713...205,966,188
Ensembl chr 1:205,958,032...205,965,877
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| G
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Slc25a23
|
solute carrier family 25 member 23
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLC25A23 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 9:1,969,633...1,985,365
Ensembl chr 9:1,969,357...1,985,365
|
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| G
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Slc25a25
|
solute carrier family 25 member 25
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC25A25 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:36,106,448...36,139,812
Ensembl chr 3:36,106,449...36,140,011
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| G
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Slc25a27
|
solute carrier family 25, member 27
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLC25A27 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:24,804,183...24,831,219
Ensembl chr 9:24,804,185...24,831,217
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| G
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Slc25a28
|
solute carrier family 25 member 28
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC25A28 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:252,480,106...252,491,365
Ensembl chr 1:252,480,128...252,491,342
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| G
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Slc25a34
|
solute carrier family 25, member 34
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLC25A34 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 5:159,215,120...159,219,892
Ensembl chr 5:159,215,120...159,219,892
|
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| G
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Slc25a35
|
solute carrier family 25, member 35
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLC25A35 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:54,172,138...54,176,359
Ensembl chr10:54,172,202...54,197,016
|
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| G
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Slc25a42
|
solute carrier family 25, member 42
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLC25A42 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr16:19,247,874...19,286,598
Ensembl chr16:19,247,725...19,270,976
|
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| G
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Slc26a3
|
solute carrier family 26 member 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLC26A3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:53,751,415...53,792,300
Ensembl chr 6:53,751,415...53,792,294
|
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| G
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Slc26a4
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solute carrier family 26 member 4
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC26A4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:53,835,102...53,873,968
Ensembl chr 6:53,835,110...53,873,216
|
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| G
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Slc26a7
|
solute carrier family 26 member 7
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLC26A7 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:32,681,653...32,819,110
Ensembl chr 5:32,684,288...32,818,905
|
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| G
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Slc27a1
|
solute carrier family 27 member 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLC27A1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr16:18,311,859...18,337,024
Ensembl chr16:18,313,015...18,330,045
|
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| G
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Slc27a3
|
solute carrier family 27 member 3
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC27A3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:178,150,835...178,155,503
Ensembl chr 2:178,150,835...178,155,503
|
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| G
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Slc27a4
|
solute carrier family 27 member 4
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC27A4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:33,472,903...33,485,824
Ensembl chr 3:33,472,903...33,485,824
|
|
| G
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Slc27a6
|
solute carrier family 27 member 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLC27A6 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr18:54,238,697...54,297,595
Ensembl chr18:54,238,729...54,312,632
|
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| G
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Slc2a1
|
solute carrier family 2 member 1
|
increases expression multiple interactions
|
ISO
|
Nickel results in increased expression of SLC2A1 mRNA Celecoxib inhibits the reaction [Nickel results in increased expression of SLC2A1 mRNA]; Dexamethasone inhibits the reaction [Nickel results in increased expression of SLC2A1 mRNA]; Indomethacin inhibits the reaction [Nickel results in increased expression of SLC2A1 mRNA]
|
CTD |
PMID:24768652 PMID:25583101 PMID:27452194 |
|
NCBI chr 5:138,002,522...138,030,742
Ensembl chr 5:138,002,522...138,030,742
|
|
| G
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Slc2a12
|
solute carrier family 2 member 12
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLC2A12 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:24,623,558...24,683,577
Ensembl chr 1:24,589,707...24,694,290
|
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| G
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Slc2a3
|
solute carrier family 2 member 3
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC2A3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:157,632,887...157,698,034
Ensembl chr 4:157,632,887...157,646,186
|
|
| G
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Slc2a5
|
solute carrier family 2 member 5
|
affects expression increases expression multiple interactions
|
ISO
|
Nickel affects the expression of SLC2A5 mRNA Nickel results in increased expression of SLC2A5 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of SLC2A5 mRNA]
|
CTD |
PMID:14575637 PMID:25583101 |
|
NCBI chr 5:165,857,412...165,892,928
Ensembl chr 5:165,866,172...165,894,038
|
|
| G
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Slc2a6
|
solute carrier family 2 member 6
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC2A6 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:30,746,472...30,753,287
Ensembl chr 3:30,745,995...30,753,287
|
|
| G
|
Slc30a6
|
solute carrier family 30 member 6
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC30A6 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 6:26,772,804...26,802,656
Ensembl chr 6:26,772,804...26,802,656
|
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| G
|
Slc30a7
|
solute carrier family 30 member 7
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC30A7 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 2:206,544,800...206,607,087
Ensembl chr 2:206,544,800...206,607,043
|
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| G
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Slc34a2
|
solute carrier family 34 member 2
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC34A2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:62,123,313...62,153,020
Ensembl chr14:62,123,316...62,143,360
|
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| G
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Slc35a1
|
solute carrier family 35 member A1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLC35A1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 5:54,021,896...54,044,677
Ensembl chr 5:54,021,896...54,044,677
|
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| G
|
Slc35a2
|
solute carrier family 35 member A2
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC35A2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr X:17,280,072...17,288,928
Ensembl chr X:17,280,074...17,288,613
|
|
| G
|
Slc35a4
|
solute carrier family 35, member A4
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of SLC35A4 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of SLC35A4 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr18:28,555,471...28,558,639
Ensembl chr18:28,545,756...28,558,725
|
|
| G
|
Slc35a5
|
solute carrier family 35, member A5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLC35A5 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr11:69,159,435...69,180,503
Ensembl chr11:69,159,384...69,180,502
|
|
| G
|
Slc35e3
|
solute carrier family 35, member E3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLC35E3 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 7:55,222,962...55,236,022
Ensembl chr 7:55,219,998...55,236,035
|
|
| G
|
Slc35f1
|
solute carrier family 35, member F1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLC35F1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr20:32,573,091...32,961,466
Ensembl chr20:32,573,428...32,961,465
|
|
| G
|
Slc35g1
|
solute carrier family 35, member G1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLC35G1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:245,576,011...245,584,533
Ensembl chr 1:245,575,996...245,584,529
|
|
| G
|
Slc36a1
|
solute carrier family 36 member 1
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC36A1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:39,819,753...39,858,068
Ensembl chr10:39,825,023...39,858,066
|
|
| G
|
Slc37a2
|
solute carrier family 37 member 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLC37A2 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 8:45,134,596...45,160,551
Ensembl chr 8:45,134,596...45,277,989
|
|
| G
|
Slc38a10
|
solute carrier family 38, member 10
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC38A10 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:105,885,250...105,935,043
Ensembl chr10:105,885,250...105,935,043
|
|
| G
|
Slc38a2
|
solute carrier family 38, member 2
|
multiple interactions affects expression
|
ISO
|
trichostatin A inhibits the reaction [Nickel affects the expression of SLC38A2 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 7:129,730,450...129,742,619
Ensembl chr 7:129,730,450...129,742,619
|
|
| G
|
Slc38a4
|
solute carrier family 38, member 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLC38A4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:130,022,039...130,082,169
Ensembl chr 7:130,023,980...130,082,097
|
|
| G
|
Slc39a14
|
solute carrier family 39 member 14
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC39A14 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr15:51,786,517...51,833,260
Ensembl chr15:51,786,623...51,833,229
|
|
| G
|
Slc39a8
|
solute carrier family 39 member 8
|
increases expression multiple interactions
|
ISO
|
Nickel results in increased expression of SLC39A8 mRNA Nickel inhibits the reaction [SLC39A8 protein results in increased uptake of Zinc]
|
CTD |
PMID:24768652 PMID:25583101 PMID:27956349 |
|
NCBI chr 2:226,845,686...226,992,668
Ensembl chr 2:226,929,644...226,992,667
|
|
| G
|
Slc40a1
|
solute carrier family 40 member 1
|
multiple interactions decreases expression
|
ISO
|
Nickel inhibits the reaction [SLC40A1 protein results in increased export of Manganese] Nickel results in decreased expression of SLC40A1 mRNA
|
CTD |
PMID:22178646 PMID:24768652 PMID:25583101 |
|
NCBI chr 9:55,525,457...55,633,463
Ensembl chr 9:55,525,532...55,543,460
|
|
| G
|
Slc41a2
|
solute carrier family 41 member 2
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC41A2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 7:22,271,298...22,378,764
Ensembl chr 7:22,271,313...22,378,764
|
|
| G
|
Slc43a3
|
solute carrier family 43, member 3
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC43A3 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:90,414,822...90,450,654
Ensembl chr 3:90,415,977...90,436,976
|
|
| G
|
Slc44a5
|
solute carrier family 44, member 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLC44A5 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:245,570,875...245,866,369
Ensembl chr 2:245,570,829...245,867,780
|
|
| G
|
Slc46a2
|
solute carrier family 46, member 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLC46A2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 5:79,594,003...79,603,074
Ensembl chr 5:79,595,150...79,603,114
|
|
| G
|
Slc47a1
|
solute carrier family 47 member 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLC47A1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr10:46,533,580...46,590,128
Ensembl chr10:46,533,583...46,587,096
|
|
| G
|
Slc47a2
|
solute carrier family 47 member 2
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC47A2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:46,490,262...46,532,954
Ensembl chr10:46,489,831...46,533,425
|
|
| G
|
Slc4a8
|
solute carrier family 4 member 8
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC4A8 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 7:133,742,830...133,818,056
Ensembl chr 7:133,742,830...133,818,056
|
|
| G
|
Slc51a
|
solute carrier family 51 member A
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC51A mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:81,804,141...81,818,539
Ensembl chr11:81,803,972...81,818,539
|
|
| G
|
Slc5a9
|
solute carrier family 5 member 9
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLC5A9 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 5:131,937,368...131,966,405
Ensembl chr 5:131,938,216...131,961,922
|
|
| G
|
Slc6a16
|
solute carrier family 6, member 16
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLC6A16 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:104,858,108...104,886,741
Ensembl chr 1:104,873,144...104,886,740
|
|
| G
|
Slc6a2
|
solute carrier family 6 member 2
|
decreases expression
|
EXP ISO
|
Nickel results in decreased expression of SLC6A2 mRNA
|
CTD |
PMID:18812211 PMID:24768652 PMID:25583101 |
|
NCBI chr19:30,183,289...30,228,292
Ensembl chr19:30,183,383...30,223,348
|
|
| G
|
Slc6a4
|
solute carrier family 6 member 4
|
decreases expression
|
EXP
|
Nickel results in decreased expression of SLC6A4 mRNA
|
CTD |
PMID:18835401 |
|
NCBI chr10:62,322,688...62,357,060
Ensembl chr10:62,324,254...62,357,056
|
|
| G
|
Slc6a6
|
solute carrier family 6 member 6
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC6A6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:125,752,340...125,826,033
Ensembl chr 4:125,752,372...125,826,032
|
|
| G
|
Slc7a11
|
solute carrier family 7 member 11
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC7A11 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:136,532,912...136,668,560
Ensembl chr 2:136,532,246...136,695,695
|
|
| G
|
Slc7a5
|
solute carrier family 7 member 5
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC7A5 mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr19:66,843,808...66,872,412
Ensembl chr19:66,843,808...66,872,412
|
|
| G
|
Slc7a7
|
solute carrier family 7 member 7
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC7A7 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr15:31,792,122...31,852,732
Ensembl chr15:31,792,125...31,835,683
|
|
| G
|
Slc8a1
|
solute carrier family 8 member A1
|
increases uptake decreases expression multiple interactions
|
ISO
|
SLC8A1 protein results in increased uptake of Nickel Nickel results in decreased expression of SLC8A1 mRNA Calcium inhibits the reaction [SLC8A1 protein results in increased uptake of Nickel]; Sodium promotes the reaction [SLC8A1 protein results in increased uptake of Nickel]
|
CTD |
PMID:10329968 PMID:23195993 |
|
NCBI chr 6:18,975,498...19,299,704
Ensembl chr 6:18,946,798...19,287,964
|
|
| G
|
Slc9a1
|
solute carrier family 9 member A1
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC9A1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:150,859,412...150,913,525
Ensembl chr 5:150,860,228...150,913,517
|
|
| G
|
Slc9b2
|
solute carrier family 9 member B2
|
increases expression
|
ISO
|
Nickel results in increased expression of SLC9B2 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 2:226,400,358...226,435,039
Ensembl chr 2:226,410,263...226,435,030
|
|
| G
|
Slco4c1
|
solute carrier organic anion transporter family, member 4C1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLCO4C1 mRNA
|
CTD |
PMID:23195993 PMID:24768652 |
|
NCBI chr 9:104,624,802...104,676,462
Ensembl chr 9:104,624,802...104,676,462
|
|
| G
|
Slco5a1
|
solute carrier organic anion transporter family, member 5A1
|
increases expression
|
ISO
|
Nickel results in increased expression of SLCO5A1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:11,012,001...11,141,180
Ensembl chr 5:11,012,075...11,141,177
|
|
| G
|
Slf1
|
SMC5-SMC6 complex localization factor 1
|
increases expression
|
ISO
|
Nickel results in increased expression of SLF1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:8,498,776...8,606,251
Ensembl chr 2:8,498,778...8,605,760
|
|
| G
|
Slfn4
|
schlafen family member 4
|
increases expression
|
ISO
|
Nickel results in increased expression of SLFN4 mRNA Nickel results in increased expression of SLFN12 mRNA
|
CTD |
PMID:12540486 PMID:24768652 PMID:25583101 |
|
NCBI chr10:68,492,135...68,515,674
Ensembl chr10:68,508,916...68,513,991
|
|
| G
|
Slfn5
|
schlafen family member 5
|
increases expression
|
ISO
|
Nickel results in increased expression of SLFN5 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:68,378,440...68,392,515
Ensembl chr10:68,378,449...68,392,544
|
|
| G
|
Slfn9
|
schlafen family member 9
|
increases expression
|
ISO
|
Nickel results in increased expression of SLFN11 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:68,406,641...68,420,062
Ensembl chr10:68,406,642...68,421,134
|
|
| G
|
Slfnl1
|
schlafen-like 1
|
increases expression
|
ISO
|
Nickel results in increased expression of SLFNL1 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 5:139,402,861...139,407,332
Ensembl chr 5:139,403,672...139,407,332
|
|
| G
|
Slit3
|
slit guidance ligand 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLIT3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:20,075,929...20,660,704
Ensembl chr10:20,076,021...20,660,704
|
|
| G
|
Slitrk4
|
SLIT and NTRK-like family, member 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLITRK4 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr X:147,728,163...147,755,086
Ensembl chr X:147,727,983...147,755,557
|
|
| G
|
Slitrk5
|
SLIT and NTRK-like family, member 5
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLITRK5 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr15:95,261,397...95,270,465
Ensembl chr15:95,261,005...95,276,090
|
|
| G
|
Slitrk6
|
SLIT and NTRK-like family, member 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SLITRK6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr15:93,977,812...93,984,431
Ensembl chr15:93,969,038...93,984,526
|
|
| G
|
Smad2
|
SMAD family member 2
|
multiple interactions
|
ISO
|
[nickel chloride results in increased abundance of Nickel] which results in increased phosphorylation of SMAD2 mRNA; [nickel chloride results in increased abundance of Nickel] which results in increased phosphorylation of SMAD2 protein; Acetylcysteine inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased phosphorylation of SMAD2 protein]
|
CTD |
PMID:38488660 |
|
NCBI chr18:72,124,792...72,193,345
Ensembl chr18:72,124,863...72,187,388
|
|
| G
|
Smad3
|
SMAD family member 3
|
multiple interactions
|
ISO
|
[nickel chloride results in increased abundance of Nickel] which results in increased phosphorylation of SMAD3 mRNA; [nickel chloride results in increased abundance of Nickel] which results in increased phosphorylation of SMAD3 protein; Acetylcysteine inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased phosphorylation of SMAD3 protein]
|
CTD |
PMID:38488660 |
|
NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:73,024,760...73,132,324
|
|
| G
|
Smad7
|
SMAD family member 7
|
increases expression
|
ISO
|
Nickel results in increased expression of SMAD7 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr18:71,263,508...71,291,849
Ensembl chr18:71,263,508...71,291,849
|
|
| G
|
Smap2
|
small ArfGAP2
|
increases expression
|
ISO
|
Nickel results in increased expression of SMAP2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:139,815,737...139,862,156
Ensembl chr 5:139,815,739...139,862,126
|
|
| G
|
Smarca2
|
SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SMARCA2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:233,617,277...233,784,908
Ensembl chr 1:233,617,366...233,784,869
|
|
| G
|
Smc1a
|
structural maintenance of chromosomes 1A
|
increases expression
|
ISO
|
Nickel results in increased expression of SMC1A mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr X:24,582,732...24,627,462
Ensembl chr X:24,582,690...24,627,462
|
|
| G
|
Smc2
|
structural maintenance of chromosomes 2
|
increases expression
|
ISO
|
Nickel results in increased expression of SMC2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:71,592,428...71,648,636
Ensembl chr 5:71,602,308...71,648,632
|
|
| G
|
Smc4
|
structural maintenance of chromosomes 4
|
increases expression
|
ISO
|
Nickel results in increased expression of SMC4 mRNA
|
CTD |
PMID:19031421 |
|
NCBI chr 2:155,550,262...155,578,695
Ensembl chr 2:155,550,262...155,581,937
|
|
| G
|
Smchd1
|
structural maintenance of chromosomes flexible hinge domain containing 1
|
increases expression
|
ISO
|
Nickel results in increased expression of SMCHD1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:118,690,050...118,837,281
Ensembl chr 9:118,690,057...118,833,452
|
|
| G
|
Smco4
|
single-pass membrane protein with coiled-coil domains 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SMCO4 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 8:20,594,633...20,646,916
Ensembl chr 8:20,627,338...20,646,916
|
|
| G
|
Smim11
|
small integral membrane protein 11
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SMIM11 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr11:45,019,269...45,028,926
Ensembl chr11:45,019,239...45,028,921
|
|
| G
|
Smim8
|
small integral membrane protein 8
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SMIM8 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 5:54,132,905...54,141,940
Ensembl chr 5:54,132,905...54,141,729
|
|
| G
|
Smoc1
|
SPARC related modular calcium binding 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SMOC1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 6:106,432,592...106,593,956
Ensembl chr 6:106,432,603...106,593,956
|
|
| G
|
Smox
|
spermine oxidase
|
increases expression
|
ISO
|
Nickel results in increased expression of SMOX mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 3:139,184,793...139,220,174
Ensembl chr 3:139,184,798...139,220,170 Ensembl chr X:139,184,798...139,220,170
|
|
| G
|
Smurf1
|
SMAD specific E3 ubiquitin protein ligase 1
|
multiple interactions
|
EXP
|
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of SMURF1 mRNA
|
CTD |
PMID:31734292 |
|
NCBI chr12:14,748,717...14,840,273
Ensembl chr12:14,749,043...14,840,273
|
|
| G
|
Smurf2
|
SMAD specific E3 ubiquitin protein ligase 2
|
multiple interactions
|
ISO
|
MT1 affects the reaction [Nickel affects the expression of SMURF2 mRNA]; MT2 affects the reaction [Nickel affects the expression of SMURF2 mRNA]
|
CTD |
PMID:16166738 |
|
NCBI chr10:92,261,516...92,362,185
Ensembl chr10:92,261,525...92,362,552
|
|
| G
|
Snapc3
|
small nuclear RNA activating complex, polypeptide 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SNAPC3 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 5:102,863,867...102,890,573
Ensembl chr 5:102,863,854...102,893,499
|
|
| G
|
Snapin
|
SNAP-associated protein
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SNAPIN mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 2:178,269,157...178,271,746
Ensembl chr 2:178,269,166...178,272,041
|
|
| G
|
Snca
|
synuclein alpha
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SNCA mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:91,026,474...91,127,444
Ensembl chr 4:91,026,474...91,126,315
|
|
| G
|
Sncg
|
synuclein, gamma
|
affects expression decreases expression multiple interactions
|
ISO
|
Nickel affects the expression of SNCG mRNA Nickel results in decreased expression of SNCG mRNA trichostatin A inhibits the reaction [Nickel affects the expression of SNCG mRNA]
|
CTD |
PMID:14575637 PMID:25583101 |
|
NCBI chr16:9,706,765...9,712,072
Ensembl chr16:9,706,753...9,712,076
|
|
| G
|
Snora21
|
small nucleolar RNA, H/ACA box 21
|
increases expression
|
ISO
|
Nickel results in increased expression of SNORA21 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 5:164,341,679...164,341,814
|
|
| G
|
Snrnp40
|
small nuclear ribonucleoprotein U5 subunit 40
|
increases expression
|
ISO
|
Nickel results in increased expression of SNRNP40 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 5:147,984,758...148,017,932
Ensembl chr 5:147,984,656...148,018,725
|
|
| G
|
Snrnp70
|
small nuclear ribonucleoprotein U1 subunit 70
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SNRNP70 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:104,992,518...105,012,851
Ensembl chr 1:104,992,442...105,012,851
|
|
| G
|
Sntg2
|
syntrophin, gamma 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SNTG2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 6:52,529,481...52,730,972
Ensembl chr 6:52,529,481...52,730,972
|
|
| G
|
Snx1
|
sorting nexin 1
|
multiple interactions
|
ISO
|
MT1 affects the reaction [Nickel affects the expression of SNX1 mRNA]; MT2 affects the reaction [Nickel affects the expression of SNX1 mRNA]
|
CTD |
PMID:16166738 |
|
NCBI chr 8:75,515,780...75,565,487
Ensembl chr 8:75,525,181...75,565,561
|
|
| G
|
Snx10
|
sorting nexin 10
|
increases expression
|
ISO
|
Nickel results in increased expression of SNX10 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:81,943,262...82,007,667
Ensembl chr 4:81,943,287...82,007,651
|
|
| G
|
Snx12
|
sorting nexin 12
|
multiple interactions
|
ISO
|
MT1 affects the reaction [Nickel affects the expression of SNX12 mRNA]; MT2 affects the reaction [Nickel affects the expression of SNX12 mRNA]
|
CTD |
PMID:16166738 |
|
NCBI chr X:70,267,013...70,396,948
Ensembl chr X:70,381,837...70,397,164
|
|
| G
|
Snx20
|
sorting nexin 20
|
increases expression
|
ISO
|
Nickel results in increased expression of SNX20 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr19:34,609,397...34,618,569
Ensembl chr19:34,609,412...34,618,567
|
|
| G
|
Snx8
|
sorting nexin 8
|
increases expression
|
ISO
|
Nickel results in increased expression of SNX8 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr12:19,365,746...19,414,333
Ensembl chr12:19,365,755...19,414,332
|
|
| G
|
Soat1
|
sterol O-acyltransferase 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SOAT1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr13:71,105,178...71,147,776
Ensembl chr13:71,105,178...71,147,672
|
|
| G
|
Sobp
|
sine oculis binding protein homolog
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SOBP mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr20:48,064,445...48,243,607
Ensembl chr20:48,064,445...48,243,607
|
|
| G
|
Socs1
|
suppressor of cytokine signaling 1
|
increases expression
|
ISO
|
Nickel results in increased expression of SOCS1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:5,389,574...5,391,265
Ensembl chr10:5,389,334...5,391,847
|
|
| G
|
Socs2
|
suppressor of cytokine signaling 2
|
increases expression
|
ISO
|
Nickel results in increased expression of SOCS2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:31,890,564...31,932,092
Ensembl chr 7:31,874,463...31,930,423
|
|
| G
|
Socs3
|
suppressor of cytokine signaling 3
|
increases expression
|
ISO
|
Nickel results in increased expression of SOCS3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:103,692,579...103,695,975
Ensembl chr10:103,690,976...103,704,825
|
|
| G
|
Sod1
|
superoxide dismutase 1
|
decreases expression
|
EXP
|
Nickel results in decreased expression of SOD1 mRNA
|
CTD |
PMID:19440498 |
|
NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399
|
|
| G
|
Sod2
|
superoxide dismutase 2
|
decreases expression increases expression
|
EXP ISO
|
Nickel results in decreased expression of SOD2 mRNA Nickel results in increased expression of SOD2 mRNA
|
CTD |
PMID:19440498 PMID:25583101 |
|
NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168
|
|
| G
|
Sorbs1
|
sorbin and SH3 domain containing 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SORBS1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:249,057,324...249,279,703
Ensembl chr 1:249,057,324...249,279,608
|
|
| G
|
Sorbs2
|
sorbin and SH3 domain containing 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SORBS2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr16:53,167,795...53,481,300
Ensembl chr16:53,167,827...53,358,986
|
|
| G
|
Sort1
|
sortilin 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SORT1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:198,609,466...198,690,481
Ensembl chr 2:198,612,148...198,690,481
|
|
| G
|
Sos1
|
SOS Ras/Rac guanine nucleotide exchange factor 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SOS1 mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 6:20,286,117...20,363,350
Ensembl chr 6:20,286,117...20,363,350
|
|
| G
|
Sostdc1
|
sclerostin domain containing 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SOSTDC1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:58,778,623...58,782,797
Ensembl chr 6:58,778,623...58,782,866
|
|
| G
|
Sowaha
|
sosondowah ankyrin repeat domain family member A
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SOWAHA mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:38,142,633...38,146,199
Ensembl chr10:38,144,782...38,147,171
|
|
| G
|
Sox10
|
SRY-box transcription factor 10
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SOX10 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 7:112,605,721...112,615,097
Ensembl chr 7:112,605,721...112,615,990
|
|
| G
|
Sox4
|
SRY-box transcription factor 4
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SOX4 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr17:35,876,298...35,881,004
Ensembl chr17:35,875,756...35,884,024
|
|
| G
|
Sox6
|
SRY-box transcription factor 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SOX6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:179,157,678...179,769,243
Ensembl chr 1:179,163,566...179,711,727
|
|
| G
|
Sox8
|
SRY-box transcription factor 8
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SOX8 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:15,089,357...15,094,345
Ensembl chr10:15,089,357...15,094,345
|
|
| G
|
Sp1
|
Sp1 transcription factor
|
increases activity
|
ISO
|
Nickel results in increased activity of SP1 protein
|
CTD |
PMID:19403854 |
|
NCBI chr 7:135,419,864...135,450,513
Ensembl chr 7:135,420,050...135,450,513
|
|
| G
|
Sp100
|
SP100 nuclear antigen
|
increases expression
|
ISO
|
Nickel results in increased expression of SP100 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:93,758,975...93,825,068
Ensembl chr 9:93,759,075...93,825,068
|
|
| G
|
Sp110
|
SP110 nuclear body protein
|
increases expression
|
ISO
|
Nickel results in increased expression of SP110 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:93,648,574...93,673,476
Ensembl chr 9:93,648,575...93,670,659
|
|
| G
|
Sp140
|
SP140 nuclear body protein
|
increases expression
|
ISO
|
Nickel results in increased expression of SP140 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 9:93,672,536...93,722,596
Ensembl chr 9:93,667,989...93,722,593
|
|
| G
|
Sp6
|
Sp6 transcription factor
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SP6 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr10:82,501,957...82,506,138
Ensembl chr10:82,501,726...82,508,887
|
|
| G
|
Spag17
|
sperm associated antigen 17
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SPAG17 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr 2:189,952,649...190,199,623
Ensembl chr 2:189,952,729...190,189,755
|
|
| G
|
Spag5
|
sperm associated antigen 5
|
increases expression
|
ISO
|
Nickel results in increased expression of SPAG5 mRNA
|
CTD |
PMID:19031421 PMID:25583101 |
|
NCBI chr10:63,693,300...63,714,813
Ensembl chr10:63,696,466...63,714,811
|
|
| G
|
Spast
|
spastin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SPAST mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 6:26,807,220...26,858,456
Ensembl chr 6:26,807,220...26,858,446
|
|
| G
|
Spata6
|
spermatogenesis associated 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SPATA6 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:131,821,585...131,905,011
Ensembl chr 5:131,821,585...131,905,014
|
|
| G
|
Spata6l
|
spermatogenesis associated 6-like
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SPATA6L mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 1:236,042,960...236,096,530
Ensembl chr 1:236,033,147...236,096,730
|
|
| G
|
Spata7
|
spermatogenesis associated 7
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SPATA7 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 6:123,609,519...123,655,001
Ensembl chr 6:123,609,535...123,655,001
|
|
| G
|
Spc25
|
SPC25 component of NDC80 kinetochore complex
|
increases expression
|
ISO
|
Nickel results in increased expression of SPC25 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 3:74,337,872...74,396,825
Ensembl chr 3:74,383,548...74,396,718
|
|
| G
|
Spcs3
|
signal peptidase complex subunit 3
|
increases expression
|
ISO
|
Nickel results in increased expression of SPCS3 mRNA
|
CTD |
PMID:24768652 |
|
NCBI chr16:44,038,421...44,043,855
Ensembl chr16:44,038,278...44,046,394
|
|
| G
|
Sphk1
|
sphingosine kinase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of SPHK1 mRNA
|
CTD |
PMID:12540486 |
|
NCBI chr10:102,257,413...102,263,086
Ensembl chr10:102,258,975...102,263,082
|
|
| G
|
Spi1
|
Spi-1 proto-oncogene
|
increases expression
|
ISO
|
Nickel results in increased expression of SPI1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 3:97,529,509...97,548,204
Ensembl chr 3:97,527,572...97,549,540
|
|
| G
|
Spib
|
Spi-B transcription factor
|
increases expression
|
ISO
|
Nickel results in increased expression of SPIB mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:104,155,456...104,161,311
Ensembl chr 1:104,155,464...104,161,517
|
|
| G
|
Spidr
|
scaffold protein involved in DNA repair
|
increases expression
|
ISO
|
Nickel results in increased expression of SPIDR mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr11:98,270,779...98,511,760
Ensembl chr11:98,270,224...98,528,748
|
|
| G
|
Spink1
|
serine peptidase inhibitor, Kazal type 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SPINK1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr18:36,121,626...36,133,596
Ensembl chr18:36,076,399...36,133,545
|
|
| G
|
Spint2
|
serine peptidase inhibitor, Kunitz type, 2
|
affects expression multiple interactions
|
ISO
|
Nickel affects the expression of SPINT2 mRNA trichostatin A inhibits the reaction [Nickel affects the expression of SPINT2 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 1:93,685,637...93,708,091
Ensembl chr 1:93,685,641...93,708,091
|
|
| G
|
Spire1
|
spire-type actin nucleation factor 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SPIRE1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr18:63,311,800...63,441,545
Ensembl chr18:63,311,800...63,441,534
|
|
| G
|
Spmap2
|
sperm microtubule associated protein 2
|
multiple interactions affects expression
|
ISO
|
trichostatin A inhibits the reaction [Nickel affects the expression of SPMAP2 mRNA]
|
CTD |
PMID:14575637 |
|
NCBI chr 7:10,777,984...10,788,157
Ensembl chr 7:10,778,015...10,788,155
|
|
| G
|
Spn
|
sialophorin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SPN mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 1:191,177,449...191,190,115
Ensembl chr 1:191,178,096...191,187,852
|
|
| G
|
Spock2
|
SPARC/osteonectin, cwcv and kazal like domains proteoglycan 2
|
increases expression
|
ISO
|
Nickel results in increased expression of SPOCK2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr20:28,580,262...28,607,198
Ensembl chr20:28,580,226...28,608,409
|
|
| G
|
Spon2
|
spondin 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SPON2 mRNA
|
CTD |
PMID:23195993 PMID:25583101 |
|
NCBI chr14:81,713,070...81,742,510
Ensembl chr14:81,731,188...81,742,609
|
|
| G
|
Spp1
|
secreted phosphoprotein 1
|
increases expression
|
ISO
|
Nickel results in increased expression of SPP1 mRNA
|
CTD |
PMID:12540486 PMID:24768652 PMID:25583101 |
|
NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820
|
|
| G
|
Sprr1a
|
small proline-rich protein 1A
|
increases expression
|
ISO
|
Nickel results in increased expression of SPRR1A mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:180,750,709...180,752,625
Ensembl chr 2:180,750,709...180,752,991
|
|
| G
|
Sprr1b
|
small proline-rich protein 1B
|
increases expression
|
ISO
|
Nickel results in increased expression of SPRR1B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:180,704,457...180,706,355
Ensembl chr 2:180,704,457...180,706,355
|
|
| G
|
Sprr2b
|
small proline rich protein 2B
|
increases expression
|
ISO
|
Nickel results in increased expression of SPRR2B mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:180,548,428...180,548,700
|
|
| G
|
Sprr3
|
small proline-rich protein 3
|
increases expression
|
ISO
|
Nickel results in increased expression of SPRR3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:180,723,038...180,725,695
Ensembl chr 2:180,723,061...180,725,505
|
|
| G
|
Spry1
|
sprouty RTK signaling antagonist 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SPRY1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 2:122,484,995...122,490,008
Ensembl chr 2:122,484,355...122,492,956
|
|
| G
|
Spry2
|
sprouty RTK signaling antagonist 2
|
multiple interactions decreases expression
|
ISO
|
SPRY2 mRNA affects the reaction [Nickel results in increased phosphorylation of MAPK1 protein]; SPRY2 mRNA affects the reaction [Nickel results in increased phosphorylation of MAPK3 protein]; SPRY2 protein inhibits the reaction [Nickel results in increased phosphorylation of MAPK1 protein]; SPRY2 protein inhibits the reaction [Nickel results in increased phosphorylation of MAPK3 protein] Nickel results in decreased expression of SPRY2 mRNA; Nickel results in decreased expression of SPRY2 protein
|
CTD |
PMID:20881000 |
|
NCBI chr15:89,106,809...89,111,926
Ensembl chr15:89,103,731...89,115,074
|
|
| G
|
Sptbn1
|
spectrin, beta, non-erythrocytic 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SPTBN1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr14:108,042,629...108,217,884
Ensembl chr14:108,042,629...108,217,836
|
|
| G
|
Sptlc2
|
serine palmitoyltransferase, long chain base subunit 2
|
increases expression
|
ISO
|
Nickel results in increased expression of SPTLC2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:112,679,623...112,762,470
Ensembl chr 6:112,679,623...112,762,640
|
|
| G
|
Spty2d1
|
SPT2 chromatin protein domain containing 1
|
increases expression
|
ISO
|
Nickel results in increased expression of SPTY2D1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:106,667,750...106,685,871
Ensembl chr 1:106,667,750...106,685,871
|
|
| G
|
Sqor
|
sulfide quinone oxidoreductase
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SQOR mRNA
|
CTD |
PMID:23195993 |
|
NCBI chr 3:130,294,783...130,341,655
Ensembl chr 3:130,292,814...130,340,799
|
|
| G
|
Sqstm1
|
sequestosome 1
|
multiple interactions
|
ISO
|
[nickel chloride results in increased abundance of Nickel] which affects the expression of and affects the localization of SQSTM1 protein
|
CTD |
PMID:36794572 |
|
NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750
|
|
| G
|
Sra1
|
steroid receptor RNA activator 1
|
increases expression
|
ISO
|
Nickel results in increased expression of SRA1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr18:28,543,347...28,547,474
Ensembl chr18:28,543,348...28,546,575
|
|
| G
|
Src
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
multiple interactions increases phosphorylation
|
ISO EXP
|
chromium hexavalent ion inhibits the reaction [Nickel results in increased phosphorylation of SRC protein]; U 0126 inhibits the reaction [Nickel results in increased phosphorylation of SRC protein] [nickel sulfate results in increased abundance of Nickel] which results in increased expression of SRC mRNA
|
CTD |
PMID:19403854 PMID:31734292 |
|
NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:166,511,985...166,559,462
|
|
| G
|
Srcin1
|
SRC kinase signaling inhibitor 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SRCIN1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr10:82,999,295...83,066,359
Ensembl chr10:82,991,033...83,067,419
|
|
| G
|
Srgap2
|
SLIT-ROBO Rho GTPase activating protein 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SRGAP2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr13:45,298,192...45,519,330
Ensembl chr13:45,298,192...45,519,330
|
|
| G
|
Srgap3
|
SLIT-ROBO Rho GTPase activating protein 3
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SRGAP3 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 4:147,391,082...147,626,407
Ensembl chr 4:147,395,880...147,625,713
|
|
| G
|
Srgn
|
serglycin
|
increases expression
|
ISO
|
Nickel results in increased expression of SRGN mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr20:30,985,508...31,022,296
Ensembl chr20:30,985,508...31,000,327
|
|
| G
|
Srl
|
sarcalumenin
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SRL mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:11,540,365...11,584,506
Ensembl chr10:11,540,443...11,584,504
|
|
| G
|
Srm
|
spermidine synthase
|
increases expression
|
ISO
|
Nickel results in increased expression of SRM mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 5:164,309,002...164,312,203
Ensembl chr 5:164,308,991...164,332,705
|
|
| G
|
Srr
|
serine racemase
|
increases expression
|
ISO
|
Nickel results in increased expression of SRR mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:60,267,936...60,285,094
Ensembl chr10:60,268,859...60,285,100
|
|
| G
|
Srsf2
|
serine and arginine rich splicing factor 2
|
increases expression
|
ISO
|
Nickel results in increased expression of SRSF2 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr10:102,550,962...102,554,200
Ensembl chr10:102,553,072...102,554,141
|
|
| G
|
Srsf6
|
serine and arginine rich splicing factor 6
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SRSF6 mRNA
|
CTD |
PMID:18922574 |
|
NCBI chr 3:172,009,072...172,014,395
Ensembl chr 3:172,009,061...172,014,392
|
|
| G
|
Ssbp2
|
single-stranded DNA binding protein 2
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SSBP2 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 2:24,385,494...24,673,768
Ensembl chr 2:24,385,687...24,673,768
|
|
| G
|
Ssc5d
|
scavenger receptor cysteine rich family member with 5 domains
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SSC5D mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr 1:77,920,781...77,939,284
Ensembl chr 1:77,920,783...77,938,574
|
|
| G
|
Ssh1
|
slingshot protein phosphatase 1
|
increases expression
|
ISO
|
Nickel results in increased expression of SSH1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr12:48,281,756...48,343,812
Ensembl chr12:48,281,756...48,343,812
|
|
| G
|
Sspn
|
sarcospan
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SSPN mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 4:180,620,762...180,666,893
Ensembl chr 4:180,627,848...180,662,284
|
|
| G
|
Ssr1
|
signal sequence receptor subunit 1
|
increases expression
|
ISO
|
Nickel results in increased expression of SSR1 mRNA
|
CTD |
PMID:25583101 |
|
NCBI chr17:27,039,203...27,067,352
Ensembl chr17:27,039,269...27,067,348
|
|
| G
|
Sstr1
|
somatostatin receptor 1
|
decreases expression
|
ISO
|
Nickel results in decreased expression of SSTR1 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
|
NCBI chr 6:81,567,237...81,571,759
Ensembl chr 6:81,566,850...81,571,992
|
|
| G
|
St14
|
ST14 transmembrane serine protease matriptase
|
increases expression
|
ISO
|
Nickel results in increased expression of ST14 mRNA
|
CTD |
PMID:24768652 PMID:25583101 |
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NCBI chr 8:37,798,994...37,839,881
Ensembl chr 8:37,798,995...37,855,652
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| G
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St3gal1
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ST3 beta-galactoside alpha-2,3-sialyltransferase 1
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increases expression
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ISO
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Nickel results in increased expression of ST3GAL1 mRNA
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CTD |
PMID:24768652 PMID:25583101 |
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NCBI chr 7:100,734,300...100,802,443
Ensembl chr 7:100,734,300...100,745,242
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| G
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St3gal3
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ST3 beta-galactoside alpha-2,3-sialyltransferase 3
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decreases expression
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ISO
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Nickel results in decreased expression of ST3GAL3 mRNA
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CTD |
PMID:25583101 |
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NCBI chr 5:136,755,780...136,958,081
Ensembl chr 5:136,755,678...136,955,987
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| G
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St6gal2
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ST6 beta-galactoside alpha-2,6-sialyltransferase 2
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decreases expression
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ISO
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Nickel results in decreased expression of ST6GAL2 mRNA
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CTD |
PMID:24768652 PMID:25583101 |
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NCBI chr 9:9,508,928...9,606,900
Ensembl chr 9:9,509,548...9,594,007
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| G
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St6galnac5
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ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
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decreases expression
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ISO
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Nickel results in decreased expression of ST6GALNAC5 mRNA
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CTD |
PMID:25583101 |
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NCBI chr 2:244,398,604...244,571,100
Ensembl chr 2:244,402,589...244,571,097
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| G
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St7l
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suppression of tumorigenicity 7-like
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decreases expression
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ISO
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Nickel results in decreased expression of ST7L mRNA
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CTD |
PMID:24768652 |
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NCBI chr 2:195,052,939...195,122,755
Ensembl chr 2:195,052,922...195,175,857
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| G
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St8sia1
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ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
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increases expression
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ISO
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Nickel results in increased expression of ST8SIA1 mRNA
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CTD |
PMID:25583101 |
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NCBI chr 4:177,513,966...177,651,553
Ensembl chr 4:177,520,926...177,651,553
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| G
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St8sia4
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ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
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decreases expression increases expression
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ISO
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Nickel results in decreased expression of ST8SIA4 mRNA Nickel results in increased expression of ST8SIA4 mRNA
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CTD |
PMID:23195993 PMID:25583101 |
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NCBI chr 9:103,437,479...103,532,008
Ensembl chr 9:103,437,479...103,532,008
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| G
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Stac2
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SH3 and cysteine rich domain 2
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decreases expression
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ISO
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Nickel results in decreased expression of STAC2 mRNA
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CTD |
PMID:25583101 |
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NCBI chr10:83,528,741...83,544,583
Ensembl chr10:83,528,741...83,544,583
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| G
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Stam2
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signal transducing adaptor molecule 2
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decreases expression
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ISO
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Nickel results in decreased expression of STAM2 mRNA
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CTD |
PMID:23195993 |
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NCBI chr 3:57,597,557...57,643,915
Ensembl chr 3:57,597,559...57,643,915
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| G
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Stambpl1
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STAM binding protein-like 1
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increases expression
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ISO
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Nickel results in increased expression of STAMBPL1 mRNA
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CTD |
PMID:25583101 |
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NCBI chr 1:241,095,695...241,158,225
Ensembl chr 1:241,113,239...241,158,225
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| G
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Stap1
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signal transducing adaptor family member 1
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increases expression
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ISO
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Nickel results in increased expression of STAP1 mRNA
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CTD |
PMID:24768652 |
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NCBI chr14:22,301,278...22,336,218
Ensembl chr14:22,236,616...22,342,652
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| G
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Stard4
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StAR-related lipid transfer domain containing 4
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increases expression
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ISO
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Nickel results in increased expression of STARD4 mRNA
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CTD |
PMID:25583101 |
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NCBI chr18:25,088,831...25,104,172
Ensembl chr18:25,091,255...25,104,172
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| G
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Stard9
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StAR-related lipid transfer domain containing 9
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decreases expression
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ISO
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Nickel results in decreased expression of STARD9 mRNA
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CTD |
PMID:24768652 PMID:25583101 |
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NCBI chr 3:128,034,866...128,150,493
Ensembl chr 3:128,034,908...128,127,402
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| G
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Stat1
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signal transducer and activator of transcription 1
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multiple interactions increases expression decreases expression
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ISO
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STAT1 protein affects the reaction [chromium hexavalent ion inhibits the reaction [Nickel results in increased expression of VEGFA mRNA]]; STAT1 protein affects the reaction [chromium hexavalent ion inhibits the reaction [Nickel results in increased stability of and results in increased expression of HIF1A protein]] Nickel results in increased expression of STAT1 mRNA Nickel results in decreased expression of STAT1 mRNA
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CTD |
PMID:19403854 PMID:23195993 PMID:24768652 PMID:25583101 |
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NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:56,911,523...57,077,346
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| G
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Stat2
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signal transducer and activator of transcription 2
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decreases expression
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ISO
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Nickel results in decreased expression of STAT2 mRNA
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CTD |
PMID:23195993 |
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NCBI chr 7:1,287,025...1,302,858
Ensembl chr 7:1,287,024...1,303,459
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| G
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Stat3
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signal transducer and activator of transcription 3
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increases expression multiple interactions
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ISO
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Nickel results in increased expression of STAT3 mRNA 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide inhibits the reaction [[Nickel co-treated with lipopolysaccharide, E. coli O26-B6] results in increased phosphorylation of STAT3 protein]; [Nickel co-treated with lipopolysaccharide, E. coli O26-B6] results in increased phosphorylation of STAT3 protein; N'-(7-fluoroH-pyrrolo(1,2-a)quinoxalin-4-yl)pyrazine-2-carbohydrazide promotes the reaction [[Nickel co-treated with lipopolysaccharide, E. coli O26-B6] results in increased phosphorylation of STAT3 protein]
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CTD |
PMID:24768652 PMID:25583101 PMID:35623502 |
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NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359
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| G
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Stat4
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signal transducer and activator of transcription 4
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increases expression
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ISO
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Nickel results in increased expression of STAT4 mRNA
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CTD |
PMID:25583101 |
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NCBI chr 9:56,964,617...57,080,523
Ensembl chr 9:56,911,523...57,077,346
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| G
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Stat5a
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signal transducer and activator of transcription 5A
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increases expression
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ISO
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Nickel results in increased expression of STAT5A mRNA
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CTD |
PMID:24768652 PMID:25583101 |
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NCBI chr10:86,285,859...86,310,187
Ensembl chr10:86,285,547...86,310,184
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| G
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Stat5b
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signal transducer and activator of transcription 5B
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multiple interactions
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EXP
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[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of STAT5B mRNA
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CTD |
PMID:31734292 |
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NCBI chr10:86,205,148...86,276,178
Ensembl chr10:86,207,293...86,275,990
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| G
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Stc1
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stanniocalcin 1
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increases expression
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ISO
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Nickel results in increased expression of STC1 mRNA
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CTD |
PMID:24768652 |
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NCBI chr15:50,709,439...50,720,093
Ensembl chr15:50,709,415...50,720,082
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| G
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Stc2
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stanniocalcin 2
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increases expression
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ISO
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Nickel results in increased expression of STC2 mRNA
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CTD |
PMID:24768652 |
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NCBI chr10:16,755,508...16,765,275
Ensembl chr10:16,755,267...16,767,447
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| G
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Steap1
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STEAP family member 1
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increases expression
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ISO
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Nickel results in increased expression of STEAP1 mRNA
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CTD |
PMID:24768652 PMID:25583101 |
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NCBI chr 4:29,231,809...29,242,317
Ensembl chr 4:29,231,753...29,242,317
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| G
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Steap2
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STEAP2 metalloreductase
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increases expression
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ISO
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Nickel results in increased expression of STEAP2 mRNA
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CTD |
PMID:25583101 |
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NCBI chr 4:29,302,487...29,323,006
Ensembl chr 4:29,303,381...29,330,620
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| G
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Steap4
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STEAP4 metalloreductase
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increases expression decreases expression
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ISO
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Nickel results in increased expression of STEAP4 mRNA Nickel results in decreased expression of STEAP4 mRNA
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CTD |
PMID:12540486 PMID:23195993 PMID:24768652 PMID:25583101 |
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NCBI chr 4:27,032,096...27,054,769
Ensembl chr 4:27,009,584...27,067,105
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| G
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Sting1
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stimulator of interferon response cGAMP interactor 1
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increases expression
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ISO
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Nickel results in increased expression of STING1 mRNA
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CTD |
PMID:24768652 PMID:25583101 |
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NCBI chr18:27,606,196...27,612,544
Ensembl chr18:27,606,196...27,611,947
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| G
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Stip1
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stress-induced phosphoprotein 1
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increases expression decreases expression
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ISO
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Nickel results in increased expression of STIP1 mRNA Nickel results in decreased expression of STIP1 mRNA
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CTD |
PMID:23195993 PMID:24768652 |
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NCBI chr 1:213,638,641...213,657,654
Ensembl chr 1:213,638,641...213,657,654
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| G
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Stk10
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serine/threonine kinase 10
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increases expression
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ISO
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Nickel results in increased expression of STK10 mRNA
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CTD |
PMID:25583101 |
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NCBI chr10:17,622,149...17,716,337
Ensembl chr10:17,622,162...17,716,332
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| G
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Stk17b
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serine/threonine kinase 17b
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increases expression
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ISO
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Nickel results in increased expression of STK17B mRNA
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CTD |
PMID:24768652 PMID:25583101 |
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NCBI chr 9:62,801,912...62,832,511
Ensembl chr 9:62,803,005...62,832,511
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| G
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Stk32a
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serine/threonine kinase 32A
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decreases expression
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ISO
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Nickel results in decreased expression of STK32A mRNA
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CTD |
PMID:24768 |