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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:N-acetyl-beta-D-glucosamine
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Accession:CHEBI:28009 term browser browse the term
Definition:An N-acetyl-D-glucosamine having beta-configuration at the anomeric centre.
Synonyms:exact_synonym: 2-acetamido-2-deoxy-beta-D-glucopyranose;   2-acetamido-2-deoxyhexopyranose
 related_synonym: 2-(acetylamino)-2-deoxy-beta-D-glucopyranose;   2-Acetamido-2-deoxy-D-glucose;   2-Acetylamino-2-deoxy-D-glucose;   Acetylglucosamine;   Formula=C8H15NO6;   GlcNAc-beta;   InChI=1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6-,7-,8-/m1/s1;   InChIKey=OVRNDRQMDRJTHS-FMDGEEDCSA-N;   N-Acetyl-D-glucosamine;   N-acetylglucosamine;   SMILES=CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O;   WURCS=2.0/1,1,0/[a2122h-1b_1-5_2*NCC/3=O]/1/;   betaGlcNAc
 alt_id: CHEBI:21579;   CHEBI:44166;   CHEBI:7140;   CHEBI:7169
 xref: CAS:7512-17-6;   Drug_Central:4615;   GlyGen:G49108TO;   GlyTouCan:G49108TO;   Gmelin:721281;   HMDB:HMDB0000803;   KEGG:C03878
 xref_mesh: MESH:D000117
 xref: PDB:2FIK;   PDB:2Q86;   PDBeChem:NAG;   PMID:15692805;   PMID:16537470;   PMID:17991151;   PMID:18295796;   PMID:19443021;   PMID:25568069;   PMID:31537530;   PMID:32568414;   PMID:7521740;   Reaxys:1247660



show annotations for term's descendants           Sort by:
N-acetyl-beta-D-glucosamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angptl4 angiopoietin-like 4 increases expression
decreases expression
ISO Acetylglucosamine results in increased expression of ANGPTL4 mRNA
Acetylglucosamine results in decreased expression of ANGPTL4 mRNA
CTD PMID:18047607 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Ap1s3 adaptor related protein complex 1 subunit sigma 3 decreases expression ISO Acetylglucosamine results in decreased expression of AP1S3 mRNA CTD PMID:18047607 NCBI chr 9:80,950,402...81,009,889
Ensembl chr 9:80,950,715...81,009,798
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO [APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Acetylglucosamine; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Acetylglucosamine] CTD PMID:39172838 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta decreases expression ISO Acetylglucosamine results in decreased expression of ARHGDIB mRNA CTD PMID:18047607 NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658
JBrowse link
G Arpc4 actin related protein 2/3 complex, subunit 4 decreases expression ISO Acetylglucosamine results in decreased expression of ARPC4 mRNA CTD PMID:18047607 NCBI chr 4:146,522,255...146,532,784
Ensembl chr 4:146,522,176...146,532,785
JBrowse link
G Calml5 calmodulin-like 5 increases expression ISO Acetylglucosamine results in increased expression of CALML5 mRNA CTD PMID:18047607 NCBI chr17:66,394,433...66,395,352 JBrowse link
G Cat catalase increases expression ISO Acetylglucosamine results in increased expression of CAT mRNA CTD PMID:18047607 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 decreases expression ISO Acetylglucosamine results in decreased expression of CCT5 mRNA CTD PMID:18047607 NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930
JBrowse link
G Cdkl1 cyclin dependent kinase like 1 decreases expression ISO Acetylglucosamine results in decreased expression of CDKL1 mRNA CTD PMID:18047607 NCBI chr 6:88,224,154...88,273,434
Ensembl chr 6:88,224,143...88,270,276
JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO Acetylglucosamine results in increased expression of CES1 mRNA CTD PMID:18047607 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
JBrowse link
G Dct dopachrome tautomerase increases expression ISO Acetylglucosamine results in increased expression of DCT mRNA CTD PMID:18047607 NCBI chr15:95,062,006...95,100,863
Ensembl chr15:95,062,003...95,100,836
JBrowse link
G Diaph2 diaphanous-related formin 2 decreases expression ISO Acetylglucosamine results in decreased expression of DIAPH2 mRNA CTD PMID:18047607 NCBI chr  X:92,395,189...93,234,521
Ensembl chr  X:92,395,251...93,229,869
JBrowse link
G Eno2 enolase 2 increases expression ISO Acetylglucosamine results in increased expression of ENO2 mRNA CTD PMID:18047607 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
JBrowse link
G Fbxo10 F-box protein 10 increases expression ISO Acetylglucosamine results in increased expression of FBXO10 mRNA CTD PMID:18047607 NCBI chr 5:59,297,016...59,343,429
Ensembl chr 5:59,297,045...59,343,348
JBrowse link
G Fbxo4 F-box protein 4 increases expression ISO Acetylglucosamine results in increased expression of FBXO4 mRNA CTD PMID:18047607 NCBI chr 2:53,174,798...53,187,792
Ensembl chr 2:53,174,798...53,187,792
JBrowse link
G Fcnb ficolin B affects binding ISO FCN1 protein binds to Acetylglucosamine CTD PMID:11012776 NCBI chr 3:11,393,713...11,402,198
Ensembl chr 3:11,393,739...11,402,151
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression ISO Acetylglucosamine results in increased expression of GPX1 mRNA CTD PMID:18047607 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gsta4 glutathione S-transferase alpha 4 increases expression ISO Acetylglucosamine results in increased expression of GSTA4 mRNA CTD PMID:18047607 NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182
JBrowse link
G Gstt2 glutathione S-transferase theta 2 increases expression ISO Acetylglucosamine results in increased expression of GSTT2 mRNA CTD PMID:18047607 NCBI chr20:12,819,617...12,823,288
Ensembl chr20:12,819,170...12,823,288
JBrowse link
G Hk2 hexokinase 2 increases expression ISO Acetylglucosamine results in increased expression of HK2 mRNA CTD PMID:18047607 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO Acetylglucosamine inhibits the reaction [TNF results in increased expression of ICAM1 protein] CTD PMID:16431966 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ifng interferon gamma increases expression
increases secretion
ISO Acetylglucosamine analog results in increased expression of IFNG mRNA
Acetylglucosamine analog results in increased secretion of IFNG protein
CTD PMID:21349367 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il4 interleukin 4 increases expression ISO Acetylglucosamine analog results in increased expression of IL4 mRNA CTD PMID:21349367 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Klrb1a killer cell lectin like receptor B1A affects binding EXP Acetylglucosamine analog binds to KLRB1A protein CTD PMID:21349367 NCBI chr 4:161,890,577...161,904,050
Ensembl chr 4:161,890,577...161,961,675
JBrowse link
G Odc1 ornithine decarboxylase 1 decreases expression ISO Acetylglucosamine results in decreased expression of ODC1 mRNA CTD PMID:18047607 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 increases expression ISO Acetylglucosamine results in increased expression of PFKFB3 mRNA CTD PMID:18047607 NCBI chr17:66,983,629...67,064,702
Ensembl chr17:66,983,686...67,063,125
JBrowse link
G Pon2 paraoxonase 2 increases expression ISO Acetylglucosamine results in increased expression of PON2 mRNA CTD PMID:18047607 NCBI chr 4:33,389,702...33,425,186
Ensembl chr 4:33,389,714...33,425,248
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO [Acetylglucosamine co-treated with Glucose] binds to PPARA protein; Acetylglucosamine inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]] CTD PMID:18812576 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A decreases expression ISO Acetylglucosamine results in decreased expression of PPP1R9A mRNA CTD PMID:18047607 NCBI chr 4:32,970,501...33,292,360
Ensembl chr 4:33,024,450...33,286,907
JBrowse link
G Prdx3 peroxiredoxin 3 increases expression ISO Acetylglucosamine results in increased expression of PRDX3 mRNA CTD PMID:18047607 NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111
JBrowse link
G Prdx5 peroxiredoxin 5 increases expression ISO Acetylglucosamine results in increased expression of PRDX5 mRNA CTD PMID:18047607 NCBI chr 1:204,099,826...204,103,589
Ensembl chr 1:204,099,826...204,114,268
JBrowse link
G Psen1 presenilin 1 multiple interactions ISO [APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Acetylglucosamine; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Acetylglucosamine] CTD PMID:39172838 NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650
JBrowse link
G Rbp1 retinol binding protein 1 decreases expression
increases expression
ISO Acetylglucosamine results in decreased expression of RBP1 mRNA
Acetylglucosamine results in increased expression of RBP1 mRNA
CTD PMID:18047607 NCBI chr 8:99,025,218...99,046,740
Ensembl chr 8:99,025,206...99,046,743
JBrowse link
G Sele selectin E affects binding ISO [Acetylglucosamine analog binds to Biotin] which binds to SELE protein; Acetylglucosamine analog binds to SELE protein CTD PMID:12191509 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Sell selectin L affects binding EXP [Acetylglucosamine analog binds to Biotin] which binds to SELL protein; Acetylglucosamine analog binds to SELL protein CTD PMID:12191509 NCBI chr13:76,416,969...76,436,444
Ensembl chr13:76,416,915...76,436,456
JBrowse link
G Selp selectin P affects binding ISO [Acetylglucosamine analog binds to Biotin] which binds to SELP protein; Acetylglucosamine analog binds to SELP protein CTD PMID:12191509 NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845
JBrowse link
G Serpina3n serpin family A member 3N decreases expression ISO Acetylglucosamine results in decreased expression of SERPINA3 mRNA CTD PMID:18047607 NCBI chr 6:123,323,623...123,331,181
Ensembl chr 6:123,323,629...123,332,433
JBrowse link
G Serpinb3a serpin family B member 3A increases expression ISO Acetylglucosamine results in increased expression of SERPINB4 mRNA CTD PMID:18047607 NCBI chr13:23,241,303...23,246,328
Ensembl chr13:23,236,972...23,246,985
JBrowse link
G Slc2a3 solute carrier family 2 member 3 decreases expression
increases expression
ISO Acetylglucosamine results in decreased expression of SLC2A3 mRNA
Acetylglucosamine results in increased expression of SLC2A3 mRNA
CTD PMID:18047607 NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472
JBrowse link
G Slc7a5 solute carrier family 7 member 5 decreases expression ISO Acetylglucosamine results in decreased expression of SLC7A5 mRNA CTD PMID:18047607 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
JBrowse link
G Snx5 sorting nexin 5 decreases expression ISO Acetylglucosamine results in decreased expression of SNX5 mRNA CTD PMID:18047607 NCBI chr 3:131,621,875...131,641,127
Ensembl chr 3:131,621,880...131,641,192
JBrowse link
G Sod2 superoxide dismutase 2 decreases expression ISO Acetylglucosamine results in decreased expression of SOD2 mRNA CTD PMID:18047607 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Tgm5 transglutaminase 5 increases expression ISO Acetylglucosamine results in increased expression of TGM5 mRNA CTD PMID:18047607 NCBI chr 3:108,008,087...108,044,013
Ensembl chr 3:108,008,143...108,043,976
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Acetylglucosamine inhibits the reaction [TNF results in increased expression of ICAM1 protein] CTD PMID:16431966 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Ttll3 tubulin tyrosine ligase like 3 decreases expression ISO Acetylglucosamine results in decreased expression of TTLL3 mRNA CTD PMID:18047607 NCBI chr 4:146,532,958...146,558,425
Ensembl chr 4:146,533,953...146,557,889
JBrowse link
G Tubb5 tubulin, beta 5 class I decreases expression ISO Acetylglucosamine results in decreased expression of TUBB mRNA CTD PMID:18047607 NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940
JBrowse link
G Tubgcp3 tubulin gamma complex component 3 decreases expression ISO Acetylglucosamine results in decreased expression of TUBGCP3 mRNA CTD PMID:18047607 NCBI chr16:76,851,859...76,912,499
Ensembl chr16:76,851,810...76,912,499
JBrowse link
G Ube2d3 ubiquitin-conjugating enzyme E2D 3 increases expression ISO Acetylglucosamine results in increased expression of UBE2D3 mRNA CTD PMID:18047607 NCBI chr 2:223,868,397...223,899,606
Ensembl chr 2:223,868,730...223,898,081
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    role 19850
      biological role 19848
        epitope 7031
          N-acetyl-beta-D-glucosamine 48
            N,N'-diacetylchitobiono-1,5-lactone 0
            [6)-beta-D-GlcpNAc-(1->] residue + 0
            alpha-D-Galf-(1->3)-beta-D-GlcpNAc 0
            alpha-D-Galp-(1->3)-beta-D-GlcpNAc + 0
            alpha-D-Galp-(1->4)-beta-D-GlcpNAc 0
            alpha-D-Galp-(1->6)-beta-D-GlcpNAc 0
            alpha-D-Manp-(1->4)-beta-D-GlcpNAc 0
            alpha-L-Fucp-(1->6)-beta-D-GlcpNAc 0
            beta-D-GalpNAc4S-(1->4)-beta-D-GlcpNAc 0
            beta-D-GclpNAc-(1->2)-[beta-D-GlcpNAc-(1->3)]-D-Manp 0
            beta-D-Glcp-(1->4)-beta-D-GlcpNAc 0
            beta-D-GlcpNAc-(1->2)-beta-D-Galp 0
            beta-D-GlcpNAc-(1->2)-beta-D-Manp 0
            beta-D-GlcpNAc-(1->2-)alpha-D-Galp 0
            beta-D-GlcpNAc-(1->3)-D-Gal-OH 0
            beta-D-GlcpNAc-(1->3)-D-Galp + 0
            beta-D-GlcpNAc-(1->3)-D-GalpNAc + 0
            beta-D-GlcpNAc-(1->3)-alpha-D-Glcp 0
            beta-D-GlcpNAc-(1->3)-alpha-D-GlcpNAc 0
            beta-D-GlcpNAc-(1->3)-beta-D-Galp-(1->4)-D-Glc-OH 0
            beta-D-GlcpNAc-(1->3)-beta-D-GalpNAc 0
            beta-D-GlcpNAc-(1->3)-beta-D-GlcpNAc 0
            beta-D-GlcpNAc-(1->3)-beta-L-Fucp + 0
            beta-D-GlcpNAc-(1->4)-D-Manp + 0
            beta-D-GlcpNAc-(1->4)-beta-D-Galp + 0
            beta-D-GlcpNAc-(1->4)-beta-D-GlcpA 0
            beta-D-GlcpNAc-(1->6)-D-Galp + 0
            beta-D-GlcpNAc-(1->6)-alpha-D-GalpNAc3S 0
            beta-D-GlcpNAc-(1->6)-alpha-D-Manp + 0
            beta-D-GlcpNAc-(1->6)-beta-D-Galp + 0
            beta-D-GlcpNAc-(1->6)-beta-D-GlcpNAc 0
            beta-L-Fucp-(1->6)-beta-D-GlcpNAc 0
            beta-L-Galp-(1->3)-beta-D-GlcpNAc 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      carbon group element atom 19757
                        carbon atom 19754
                          organic molecular entity 19754
                            heteroorganic entity 19512
                              organochalcogen compound 19275
                                organooxygen compound 19191
                                  carbohydrates and carbohydrate derivatives 15289
                                    carbohydrate 15289
                                      carbohydrate derivative 14305
                                        amino sugar 1380
                                          amino monosaccharide 1375
                                            hexosamine 1375
                                              N-acyl-hexosamine 1158
                                                N-acetylhexosamine 48
                                                  N-acetyl-D-hexosamine 48
                                                    N-acetyl-D-glucosamine 48
                                                      N-acetyl-beta-D-glucosamine 48
                                                        N,N'-diacetylchitobiono-1,5-lactone 0
                                                        [6)-beta-D-GlcpNAc-(1->] residue + 0
                                                        alpha-D-Galf-(1->3)-beta-D-GlcpNAc 0
                                                        alpha-D-Galp-(1->3)-beta-D-GlcpNAc + 0
                                                        alpha-D-Galp-(1->4)-beta-D-GlcpNAc 0
                                                        alpha-D-Galp-(1->6)-beta-D-GlcpNAc 0
                                                        alpha-D-Manp-(1->4)-beta-D-GlcpNAc 0
                                                        alpha-L-Fucp-(1->6)-beta-D-GlcpNAc 0
                                                        beta-D-GalpNAc4S-(1->4)-beta-D-GlcpNAc 0
                                                        beta-D-GclpNAc-(1->2)-[beta-D-GlcpNAc-(1->3)]-D-Manp 0
                                                        beta-D-Glcp-(1->4)-beta-D-GlcpNAc 0
                                                        beta-D-GlcpNAc-(1->2)-beta-D-Galp 0
                                                        beta-D-GlcpNAc-(1->2)-beta-D-Manp 0
                                                        beta-D-GlcpNAc-(1->2-)alpha-D-Galp 0
                                                        beta-D-GlcpNAc-(1->3)-D-Gal-OH 0
                                                        beta-D-GlcpNAc-(1->3)-D-Galp + 0
                                                        beta-D-GlcpNAc-(1->3)-D-GalpNAc + 0
                                                        beta-D-GlcpNAc-(1->3)-alpha-D-Glcp 0
                                                        beta-D-GlcpNAc-(1->3)-alpha-D-GlcpNAc 0
                                                        beta-D-GlcpNAc-(1->3)-beta-D-Galp-(1->4)-D-Glc-OH 0
                                                        beta-D-GlcpNAc-(1->3)-beta-D-GalpNAc 0
                                                        beta-D-GlcpNAc-(1->3)-beta-D-GlcpNAc 0
                                                        beta-D-GlcpNAc-(1->3)-beta-L-Fucp + 0
                                                        beta-D-GlcpNAc-(1->4)-D-Manp + 0
                                                        beta-D-GlcpNAc-(1->4)-beta-D-Galp + 0
                                                        beta-D-GlcpNAc-(1->4)-beta-D-GlcpA 0
                                                        beta-D-GlcpNAc-(1->6)-D-Galp + 0
                                                        beta-D-GlcpNAc-(1->6)-alpha-D-GalpNAc3S 0
                                                        beta-D-GlcpNAc-(1->6)-alpha-D-Manp + 0
                                                        beta-D-GlcpNAc-(1->6)-beta-D-Galp + 0
                                                        beta-D-GlcpNAc-(1->6)-beta-D-GlcpNAc 0
                                                        beta-L-Fucp-(1->6)-beta-D-GlcpNAc 0
                                                        beta-L-Galp-(1->3)-beta-D-GlcpNAc 0
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