Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:cocaine
go back to main search page
Accession:CHEBI:27958 term browser browse the term
Definition:A tropane alkaloid obtained from leaves of the South American shrub Erythroxylon coca.
Synonyms:exact_synonym: (1R,2R,3S,5S)-2-(methoxycarbonyl)tropan-3-yl benzoate;   methyl (1R,2R,3S,5S)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate
 related_synonym: 2-methyl-3beta-hydroxy-1alphaH,5alphaH-tropane-2beta-carboxylate benzoate (ester);   Benzoylmethylecgonine;   Cocain;   Cocaina;   Formula=C17H21NO4;   InChI=1S/C17H21NO4/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11/h3-7,12-15H,8-10H2,1-2H3/t12-,13+,14-,15+/m0/s1;   InChIKey=ZPUCINDJVBIVPJ-LJISPDSOSA-N;   Kokain;   Neurocaine;   SMILES=[H][C@]12CC[C@]([H])([C@H]([C@H](C1)OC(=O)c1ccccc1)C(=O)OC)N2C;   [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid, methyl ester;   beta-Cocain;   cocainum;   l-Cocain;   l-cocaine;   methyl [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate;   methyl benzoylecgonine
 alt_id: CHEBI:23346;   CHEBI:3801;   CHEBI:41642
 xref: Beilstein:3621912;   Beilstein:5291037;   Beilstein:91034;   CAS:50-36-2;   DrugBank:DB00907;   Drug_Central:723;   Gmelin:170209;   KEGG:C01416;   KEGG:D00110;   KNApSAcK:C00002285
 xref_mesh: MESH:D003042
 xref: MetaCyc:CPD-9776;   PDBeChem:COC;   PMID:11416615;   PMID:11853120;   PMID:14962054;   PMID:17551070;   PMID:19536276;   PMID:21150772;   PMID:25303034;   Reaxys:5291037;   Reaxys:91034;   Wikipedia:Cocaine
 cyclic_relationship: is_conjugate_base_of CHEBI:60056


show annotations for term's descendants           Sort by:
cocaine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aacs acetoacetyl-CoA synthetase affects expression EXP Cocaine affects the expression of AACS mRNA CTD PMID:20187946 NCBI chr12:31,113,098...31,156,411
Ensembl chr12:31,113,098...31,160,954 		JBrowse link
G Aadac arylacetamide deacetylase decreases expression EXP Cocaine results in decreased expression of AADAC mRNA CTD PMID:17898221 NCBI chr 2:144,163,436...144,186,086
Ensembl chr 2:144,135,319...144,174,734 		JBrowse link
G Aanat aralkylamine N-acetyltransferase affects response to substance ISO AANAT protein affects the susceptibility to Cocaine CTD PMID:12138020 NCBI chr10:101,827,072...101,831,805
Ensembl chr10:101,827,301...101,831,801 		JBrowse link
G Abat 4-aminobutyrate aminotransferase increases response to substance ISO ABAT mRNA results in increased susceptibility to Cocaine CTD PMID:10850552 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835 		JBrowse link
G Abca4 ATP binding cassette subfamily A member 4 decreases expression EXP Cocaine results in decreased expression of ABCA4 mRNA CTD PMID:27899881 NCBI chr 2:210,164,813...210,302,069
Ensembl chr 2:210,164,813...210,302,069 		JBrowse link
G Abca5 ATP binding cassette subfamily A member 5 multiple interactions ISO HDAC5 affects the reaction [Cocaine affects the expression of ABCA5 mRNA] CTD PMID:17988634 NCBI chr10:95,240,159...95,309,195
Ensembl chr10:95,240,154...95,308,976 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 affects expression EXP Cocaine affects the expression of ABCC3 mRNA CTD PMID:20187946 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 affects expression EXP Cocaine affects the expression of ABCC5 mRNA CTD PMID:20187946 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253 		JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 affects expression EXP Cocaine affects the expression of ABCC9 mRNA CTD PMID:20187946 NCBI chr 4:175,531,854...175,655,849
Ensembl chr 4:175,532,547...175,655,356 		JBrowse link
G Abcd4 ATP binding cassette subfamily D member 4 affects expression EXP Cocaine affects the expression of ABCD4 mRNA CTD PMID:20187946 NCBI chr 6:104,246,459...104,260,965
Ensembl chr 6:104,246,468...104,280,276 		JBrowse link
G Abhd1 abhydrolase domain containing 1 decreases expression ISO Cocaine results in decreased expression of ABHD1 mRNA CTD PMID:18355967 NCBI chr 6:25,422,526...25,427,514
Ensembl chr 6:25,422,526...25,427,514 		JBrowse link
G Abhd14a abhydrolase domain containing 14A affects expression EXP Cocaine affects the expression of ABHD14A mRNA CTD PMID:20187946 NCBI chr 8:107,079,139...107,089,004
Ensembl chr 8:107,079,144...107,086,985 		JBrowse link
G Abhd17a abhydrolase domain containing 17A, depalmitoylase affects expression EXP Cocaine affects the expression of ABHD17A mRNA CTD PMID:20187946 NCBI chr 7:9,124,332...9,132,762
Ensembl chr 7:9,124,332...9,130,762 		JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase affects expression ISO Cocaine affects the expression of ABL1 mRNA CTD PMID:15681117 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B increases expression ISO Cocaine results in increased expression of ACAA1 mRNA CTD PMID:18355967 NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:118,872,997...118,881,825 		JBrowse link
G Acan aggrecan affects expression EXP Cocaine affects the expression of ACAN mRNA CTD PMID:20187946 NCBI chr 1:132,981,582...133,044,416
Ensembl chr 1:132,981,582...133,043,627 		JBrowse link
G Ace angiotensin I converting enzyme multiple interactions ISO ACE inhibits the reaction [Cocaine affects the abundance of Dinoprostone]; ACE inhibits the reaction [Cocaine affects the abundance of Epoprostenol] CTD PMID:14738173 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Acin1 apoptotic chromatin condensation inducer 1 affects expression ISO Cocaine affects the expression of ACIN1 mRNA CTD PMID:15681117 NCBI chr15:28,102,112...28,147,001
Ensembl chr15:28,102,112...28,147,001 		JBrowse link
G Ackr2 atypical chemokine receptor 2 affects expression EXP Cocaine affects the expression of ACKR2 mRNA CTD PMID:20187946 NCBI chr 8:121,559,563...121,573,633
Ensembl chr 8:121,561,211...121,573,582 		JBrowse link
G Aco2 aconitase 2 increases expression ISO Cocaine results in increased expression of ACO2 protein modified form CTD PMID:24096156 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261 		JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 affects expression EXP Cocaine affects the expression of ACSL5 mRNA CTD PMID:20187946 NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607 		JBrowse link
G Acss1 acyl-CoA synthetase short-chain family member 1 decreases expression EXP Cocaine results in decreased expression of ACSS1 mRNA CTD PMID:27899881 NCBI chr 3:139,450,383...139,500,325
Ensembl chr 3:139,450,383...139,500,325 		JBrowse link
G Actg2 actin gamma 2, smooth muscle decreases expression ISO Cocaine results in decreased expression of ACTG2 mRNA CTD PMID:20948987 NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465 		JBrowse link
G Actn2 actinin alpha 2 increases expression ISO Cocaine results in increased expression of ACTN2 mRNA CTD PMID:15009677 PMID:16710320 NCBI chr17:58,143,334...58,210,622
Ensembl chr17:58,142,625...58,210,622 		JBrowse link
G Acvr1c activin A receptor type 1C increases expression EXP Cocaine results in increased expression of ACVR1C mRNA CTD PMID:17898221 NCBI chr 3:42,815,490...42,892,423
Ensembl chr 3:42,822,610...42,892,327 		JBrowse link
G Acy3 aminoacylase 3 affects expression EXP Cocaine affects the expression of ACY3 mRNA CTD PMID:20187946 NCBI chr 1:201,279,751...201,285,803
Ensembl chr 1:201,279,851...201,283,175 		JBrowse link
G Adam19 ADAM metallopeptidase domain 19 decreases expression EXP Cocaine results in decreased expression of ADAM19 mRNA CTD PMID:17898221 NCBI chr10:30,491,362...30,583,115
Ensembl chr10:30,491,405...30,583,105 		JBrowse link
G Adam1a ADAM metallopeptidase domain 1a multiple interactions ISO HDAC5 affects the reaction [Cocaine affects the expression of ADAM1A mRNA] CTD PMID:17988634 NCBI chr12:35,017,433...35,020,300
Ensembl chr12:35,017,315...35,020,311 		JBrowse link
G Adamts19 ADAM metallopeptidase with thrombospondin type 1 motif, 19 decreases expression EXP Cocaine results in decreased expression of ADAMTS19 mRNA CTD PMID:27899881 NCBI chr18:52,346,448...52,531,245
Ensembl chr18:52,347,428...52,530,509 		JBrowse link
G Adat2 adenosine deaminase, tRNA-specific 2 decreases expression EXP Cocaine results in decreased expression of ADAT2 mRNA CTD PMID:17898221 NCBI chr 1:7,954,520...7,975,254
Ensembl chr 1:7,954,631...7,975,251 		JBrowse link
G Adcy2 adenylate cyclase 2 affects expression EXP Cocaine affects the expression of ADCY2 mRNA CTD PMID:20187946 NCBI chr 1:34,375,639...34,822,252
Ensembl chr 1:34,375,895...34,822,236 		JBrowse link
G Adcy8 adenylate cyclase 8 affects expression EXP Cocaine affects the expression of ADCY8 mRNA CTD PMID:20187946 NCBI chr 7:96,417,310...96,665,911
Ensembl chr 7:96,417,324...96,665,911 		JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 increases expression
multiple interactions		 ISO Cocaine results in increased expression of ADCYAP1 mRNA
ADCYAP1 protein modified form affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; ADCYAP1 protein modified form affects the reaction [Cocaine results in increased expression of BAX protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide affects the reaction [IL6 protein affects the reaction [Cocaine results in increased expression of ADCYAP1 mRNA]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Cocaine results in increased expression of ADCYAP1 mRNA]; IL6 protein affects the reaction [Cocaine results in increased expression of ADCYAP1 mRNA]; TNF protein affects the reaction [Cocaine results in increased expression of ADCYAP1 mRNA]		 CTD PMID:29673861 NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773 		JBrowse link
G Adcyap1r1 ADCYAP receptor type I increases expression
multiple interactions		 ISO Cocaine results in increased expression of ADCYAP1R1 mRNA
alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide affects the reaction [IL6 protein affects the reaction [Cocaine results in increased expression of ADCYAP1R1 mRNA]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Cocaine results in increased expression of ADCYAP1R1 mRNA]; IL6 protein affects the reaction [Cocaine results in increased expression of ADCYAP1R1 mRNA]; TNF protein affects the reaction [Cocaine results in increased expression of ADCYAP1R1 mRNA]		 CTD PMID:29673861 NCBI chr 4:84,593,558...84,642,700
Ensembl chr 4:84,593,892...84,642,700 		JBrowse link
G Adgra1 adhesion G protein-coupled receptor A1 multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in increased expression of ADGRA1 mRNA CTD PMID:18355967 NCBI chr 1:194,629,744...194,673,254
Ensembl chr 1:194,629,726...194,672,550 		JBrowse link
G Adgre1 adhesion G protein-coupled receptor E1 affects expression EXP Cocaine affects the expression of ADGRE1 mRNA CTD PMID:20187946 NCBI chr 9:2,242,476...2,398,000
Ensembl chr 9:2,242,474...2,398,000 		JBrowse link
G Adgrf1 adhesion G protein-coupled receptor F1 decreases expression EXP Cocaine results in decreased expression of ADGRF1 mRNA CTD PMID:17898221 NCBI chr 9:17,661,258...17,696,359
Ensembl chr 9:17,660,930...17,711,704 		JBrowse link
G Adgrl1 adhesion G protein-coupled receptor L1 affects expression EXP Cocaine affects the expression of ADGRL1 mRNA CTD PMID:20187946 NCBI chr19:24,202,405...24,244,137
Ensembl chr19:24,204,360...24,244,139 		JBrowse link
G Adgrl3 adhesion G protein-coupled receptor L3 affects expression EXP Cocaine affects the expression of ADGRL3 mRNA CTD PMID:20187946 NCBI chr14:26,336,320...27,104,060
Ensembl chr14:26,368,277...27,105,860 		JBrowse link
G Adora1 adenosine A1 receptor affects expression
affects response to substance		 EXP
ISO		 Cocaine affects the expression of ADORA1 mRNA; Cocaine affects the expression of ADORA1 protein
ADORA1 affects the susceptibility to Cocaine		 CTD PMID:12358776 PMID:19092996 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801 		JBrowse link
G Adora2a adenosine A2a receptor increases response to substance
increases expression		 ISO ADORA2A results in increased susceptibility to Cocaine
Cocaine deficiency results in increased expression of ADORA2A mRNA		 CTD PMID:16123743 PMID:27126842 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Adora2b adenosine A2B receptor affects expression EXP Cocaine affects the expression of ADORA2B mRNA CTD PMID:20187946 NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772 		JBrowse link
G Adra1b adrenoceptor alpha 1B increases response to substance ISO ADRA1B gene results in increased susceptibility to Cocaine CTD PMID:14556232 NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919 		JBrowse link
G Adrb1 adrenoceptor beta 1 multiple interactions
affects expression		 EXP Betaxolol affects the reaction [Cocaine affects the expression of ADRB1 protein]; Betaxolol inhibits the reaction [Cocaine affects the expression of ADRB1 protein] CTD PMID:17513029 PMID:18596687 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
G Aff4 ALF transcription elongation factor 4 increases expression EXP Cocaine results in increased expression of AFF4 mRNA CTD PMID:17898221 NCBI chr10:37,498,825...37,579,751
Ensembl chr10:37,498,825...37,579,751 		JBrowse link
G Afmid arylformamidase increases expression EXP Cocaine results in increased expression of AFMID mRNA CTD PMID:17898221 NCBI chr10:103,046,129...103,061,718
Ensembl chr10:103,046,180...103,061,718 		JBrowse link
G Afp alpha-fetoprotein increases expression EXP Cocaine results in increased expression of AFP mRNA CTD PMID:27899881 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480 		JBrowse link
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 affects expression EXP Cocaine affects the expression of AGAP2 mRNA CTD PMID:20187946 NCBI chr 7:62,897,282...62,914,295
Ensembl chr 7:62,897,282...62,914,295 		JBrowse link
G Ago2 argonaute RISC catalytic component 2 multiple interactions
affects response to substance		 ISO AGO2 protein affects the reaction [Cocaine results in increased expression of MIR130A mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR136 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR137 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR138-1 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR148B mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR154 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR181A1 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR186 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR301B mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR324 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR337 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR369 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR376A mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR376C mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR380 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR384 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR467B mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR488 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR500 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR544 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR665 mRNA]
AGO2 protein affects the susceptibility to Cocaine		 CTD PMID:20643829 NCBI chr 7:105,018,202...105,105,118
Ensembl chr 7:105,029,120...105,104,974 		JBrowse link
G Aif1l allograft inflammatory factor 1-like decreases expression ISO Cocaine results in decreased expression of AIF1L mRNA CTD PMID:15009677 NCBI chr 3:15,229,476...15,254,033
Ensembl chr 3:15,229,524...15,254,023 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 affects expression
increases expression		 ISO Cocaine affects the expression of AIFM1 mRNA
Cocaine results in increased expression of AIFM1 mRNA		 CTD PMID:15681117 PMID:18000554 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256 		JBrowse link
G Aifm2 AIF family member 2 affects expression ISO Cocaine affects the expression of AIFM2 mRNA CTD PMID:15681117 NCBI chr20:29,654,283...29,679,239
Ensembl chr20:29,652,927...29,679,236 		JBrowse link
G Ak1 adenylate kinase 1 decreases expression ISO Cocaine results in decreased expression of AK1 mRNA CTD PMID:15009677 NCBI chr 3:15,912,431...15,923,045
Ensembl chr 3:15,912,485...15,923,041 		JBrowse link
G Ak3 adenylate kinase 3 affects expression EXP Cocaine affects the expression of AK3 mRNA CTD PMID:20187946 NCBI chr 1:226,737,472...226,764,647
Ensembl chr 1:226,739,318...226,764,625 		JBrowse link
G Akr1d1 aldo-keto reductase family 1, member D1 affects expression EXP Cocaine affects the expression of AKR1D1 mRNA CTD PMID:20187946 NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372 		JBrowse link
G Akr1e2 aldo-keto reductase family 1, member E2 affects expression EXP Cocaine affects the expression of AKR1E1 mRNA CTD PMID:20187946 NCBI chr17:65,735,909...65,750,441
Ensembl chr17:65,735,943...65,750,441 		JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 affects expression EXP Cocaine affects the expression of AKR7A3 mRNA CTD PMID:20187946 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 affects expression
multiple interactions
increases phosphorylation		 EXP
ISO		 Cocaine affects the expression of AKT1 mRNA
Cocaine affects the reaction [ILK protein affects the phosphorylation of AKT1 protein]
Cocaine results in increased phosphorylation of AKT1 protein
[Cocaine co-treated with cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester] results in increased phosphorylation of AKT1 protein		 CTD PMID:18702665 PMID:20187946 PMID:25933444 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alcam activated leukocyte cell adhesion molecule increases expression EXP Cocaine results in increased expression of ALCAM mRNA CTD PMID:17898221 NCBI chr11:48,336,123...48,536,296
Ensembl chr11:48,336,169...48,537,954 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions EXP [[CVT-10216 results in decreased activity of ALDH2 protein] which results in increased abundance of Tetrahydropapaveroline] inhibits the reaction [Cocaine results in increased abundance of and results in increased secretion of Dopamine]; [ALDH2 protein affects the abundance of Tetrahydropapaveroline] which affects the susceptibility to Cocaine; ALDH2 protein affects the reaction [Cocaine results in increased abundance of Dopamine] CTD PMID:20729865 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Ambra1 autophagy and beclin 1 regulator 1 decreases expression EXP Cocaine results in decreased expression of AMBRA1 mRNA CTD PMID:17898221 NCBI chr 3:77,700,936...77,890,221
Ensembl chr 3:77,700,936...77,890,221 		JBrowse link
G Amh anti-Mullerian hormone increases expression EXP Cocaine results in increased expression of AMH mRNA CTD PMID:17898221 NCBI chr 7:8,906,776...8,909,192
Ensembl chr 7:8,906,836...8,909,282 		JBrowse link
G Amigo1 adhesion molecule with Ig like domain 1 affects expression EXP Cocaine affects the expression of AMIGO1 mRNA CTD PMID:20187946 NCBI chr 2:195,823,138...195,828,593
Ensembl chr 2:195,823,042...195,829,585 		JBrowse link
G Amigo3 adhesion molecule with Ig like domain 3 affects expression EXP Cocaine affects the expression of AMIGO3 mRNA CTD PMID:20187946 NCBI chr 8:108,741,899...108,743,425
Ensembl chr 8:108,693,060...108,744,555 		JBrowse link
G Amn1 antagonist of mitotic exit network 1 homolog decreases expression EXP Cocaine results in decreased expression of AMN1 mRNA CTD PMID:17898221 NCBI chr 4:182,155,140...182,182,085
Ensembl chr 4:182,155,142...182,182,016 		JBrowse link
G Ankrd54 ankyrin repeat domain 54 affects expression EXP Cocaine affects the expression of ANKRD54 mRNA CTD PMID:20187946 NCBI chr 7:110,614,942...110,627,739
Ensembl chr 7:110,614,951...110,627,675 		JBrowse link
G Anks1b ankyrin repeat and sterile alpha motif domain containing 1B decreases expression EXP Cocaine results in decreased expression of ANKS1B mRNA CTD PMID:17898221 NCBI chr 7:24,313,339...25,479,307
Ensembl chr 7:24,312,843...25,477,693 		JBrowse link
G Anxa7 annexin A7 affects expression EXP Cocaine affects the expression of ANXA7 mRNA CTD PMID:20187946 NCBI chr15:3,821,798...3,849,659
Ensembl chr15:3,821,845...3,849,385 		JBrowse link
G Ap1ar adaptor-related protein complex 1 associated regulatory protein increases expression EXP Cocaine results in increased expression of AP1AR mRNA CTD PMID:17898221 NCBI chr 2:216,276,631...216,309,020
Ensembl chr 2:216,276,631...216,309,013 		JBrowse link
G Ap2b1 adaptor related protein complex 2 subunit beta 1 affects expression EXP Cocaine affects the expression of AP2B1 mRNA CTD PMID:20187946 NCBI chr10:68,099,397...68,205,023
Ensembl chr10:68,099,547...68,205,013 		JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 increases expression EXP Cocaine results in increased expression of AP2M1 protein CTD PMID:25100957 NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140 		JBrowse link
G Ap2s1 adaptor related protein complex 2 subunit sigma 1 decreases expression ISO Cocaine results in decreased expression of AP2S1 mRNA CTD PMID:15009677 NCBI chr 1:77,417,496...77,428,903
Ensembl chr 1:77,417,477...77,428,905 		JBrowse link
G Ap5m1 adaptor related protein complex 5 subunit mu 1 affects expression EXP Cocaine affects the expression of AP5M1 mRNA CTD PMID:20187946 NCBI chr15:22,355,478...22,385,222
Ensembl chr15:22,355,500...22,377,750 		JBrowse link
G Apcs amyloid P component, serum increases expression ISO Cocaine results in increased expression of APCS protein CTD PMID:12714198 NCBI chr13:85,373,219...85,374,195
Ensembl chr13:85,373,220...85,374,298 		JBrowse link
G Aph1a aph-1 homolog A, gamma secretase subunit affects expression EXP Cocaine affects the expression of APH1A mRNA CTD PMID:20187946 NCBI chr 2:183,437,676...183,443,113
Ensembl chr 2:183,438,434...183,441,955 		JBrowse link
G Aplnr apelin receptor increases expression EXP Cocaine results in increased expression of APLNR mRNA CTD PMID:17898221 NCBI chr 3:70,217,407...70,221,052
Ensembl chr 3:70,217,385...70,221,050 		JBrowse link
G Apol11a apolipoprotein L11a decreases expression EXP Cocaine results in decreased expression of APOL11A mRNA CTD PMID:27899881 NCBI chr 7:109,248,260...109,262,266
Ensembl chr 7:109,248,942...109,253,716 		JBrowse link
G Apol2 apolipoprotein L2 increases expression ISO Cocaine results in increased expression of APOL2 mRNA CTD PMID:17205118 NCBI chr 7:109,331,367...109,338,632
Ensembl chr 7:109,331,392...109,338,558 		JBrowse link
G Apold1 apolipoprotein L domain containing 1 affects expression EXP Cocaine affects the expression of APOLD1 mRNA CTD PMID:20187946 NCBI chr 4:167,768,437...167,825,706
Ensembl chr 4:167,818,271...167,825,706 		JBrowse link
G Apoo apolipoprotein O increases expression EXP Cocaine results in increased expression of APOO protein CTD PMID:25100957 NCBI chr  X:59,157,971...59,262,940
Ensembl chr  X:59,158,049...59,262,940 		JBrowse link
G App amyloid beta precursor protein decreases expression
increases expression		 EXP
ISO		 Cocaine results in decreased expression of APP mRNA
Cocaine results in increased expression of APP mRNA		 CTD PMID:15009677 PMID:16710320 PMID:17898221 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 increases expression EXP Cocaine results in increased expression of APPL1 mRNA CTD PMID:17898221 NCBI chr16:2,118,503...2,166,741
Ensembl chr16:2,121,255...2,166,692 		JBrowse link
G Arc activity-regulated cytoskeleton-associated protein affects expression
multiple interactions
increases expression
increases expression 		EXP
ISO		 Cocaine affects the expression of ARC mRNA
Reserpine inhibits the reaction [Cocaine results in increased expression of ARC mRNA]
Cocaine results in increased expression of ARC mRNA; Cocaine results in increased expression of ARC protein
Cocaine increases expression of Arc protein in dorsal striatum and shell of nucleus accumbens
cocaine co treated with anisomycin decreases expression of Arc protein in dorsal striatum and shell of nucleus accumbens		 CTD
RGD		 PMID:7722525 PMID:12117546 PMID:15254092 PMID:17851536 PMID:18311559 More... RGD:401901591, RGD:401901591 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378 		JBrowse link
G Arf4 ADP-ribosylation factor 4 decreases expression EXP Cocaine results in decreased expression of ARF4 protein CTD PMID:25100957 NCBI chr16:1,896,692...1,913,267
Ensembl chr16:1,896,546...1,913,261 		JBrowse link
G Arhgap1 Rho GTPase activating protein 1 increases expression EXP Cocaine results in increased expression of ARHGAP1 protein CTD PMID:25100957 NCBI chr 3:77,621,377...77,643,400
Ensembl chr 3:77,620,655...77,643,396 		JBrowse link
G Arhgap29 Rho GTPase activating protein 29 decreases expression ISO Cocaine results in decreased expression of ARHGAP29 mRNA CTD PMID:12629581 NCBI chr 2:210,060,036...210,132,572
Ensembl chr 2:210,071,199...210,132,028 		JBrowse link
G Arhgap30 Rho GTPase activating protein 30 increases expression EXP Cocaine results in increased expression of ARHGAP30 mRNA CTD PMID:17898221 NCBI chr13:83,822,290...83,843,634
Ensembl chr13:83,822,283...83,854,885 		JBrowse link
G Arhgap44 Rho GTPase activating protein 44 decreases expression EXP Cocaine results in decreased expression of ARHGAP44 protein CTD PMID:25100957 NCBI chr10:49,655,583...49,822,876
Ensembl chr10:49,655,584...49,824,297 		JBrowse link
G Arhgap5 Rho GTPase activating protein 5 increases expression EXP Cocaine results in increased expression of ARHGAP5 mRNA CTD PMID:17898221 NCBI chr 6:69,975,904...70,039,299
Ensembl chr 6:69,976,214...70,037,660 		JBrowse link
G Arhgap9 Rho GTPase activating protein 9 decreases expression EXP Cocaine results in decreased expression of ARHGAP9 mRNA CTD PMID:17898221 NCBI chr 7:63,148,573...63,157,025
Ensembl chr 7:63,148,900...63,157,524 		JBrowse link
G Arhgef1 Rho guanine nucleotide exchange factor 1 affects expression EXP Cocaine affects the expression of ARHGEF1 mRNA CTD PMID:20187946 NCBI chr 1:80,499,026...80,520,954
Ensembl chr 1:80,499,131...80,520,953 		JBrowse link
G Arhgef7 Rho guanine nucleotide exchange factor 7 affects expression EXP Cocaine affects the expression of ARHGEF7 mRNA CTD PMID:20187946 NCBI chr16:77,671,021...77,782,593
Ensembl chr16:77,671,023...77,782,697 		JBrowse link
G Armcx6 armadillo repeat containing, X-linked 6 affects expression EXP Cocaine affects the expression of ARMCX6 mRNA CTD PMID:20187946 NCBI chr  X:97,929,032...97,932,031
Ensembl chr  X:97,929,041...97,931,977 		JBrowse link
G Arpc1a actin related protein 2/3 complex, subunit 1A increases expression EXP Cocaine results in increased expression of ARPC1A protein CTD PMID:25100957 NCBI chr12:9,502,496...9,525,304
Ensembl chr12:9,502,501...9,525,330 		JBrowse link
G Arpp19 cAMP-regulated phosphoprotein 19 multiple interactions EXP Cocaine inhibits the reaction [SK&F 81297 results in increased phosphorylation of ARPP19 protein] CTD PMID:11268215 NCBI chr 8:75,779,640...75,802,474
Ensembl chr 8:75,779,523...75,802,452
Ensembl chr 8:75,779,523...75,802,452 		JBrowse link
G Arpp21 cAMP regulated phosphoprotein 21 multiple interactions
increases expression		 EXP
ISO		 Cocaine inhibits the reaction [SK&F 81297 results in increased phosphorylation of ARPP21 protein]
Cocaine deficiency results in increased expression of ARPP21 mRNA		 CTD PMID:11268215 PMID:27126842 NCBI chr 8:112,034,636...112,199,273
Ensembl chr 8:112,034,642...112,194,297 		JBrowse link
G Art5 ADP-ribosyltransferase 5 increases expression EXP Cocaine results in increased expression of ART5 mRNA CTD PMID:17898221 NCBI chr 1:156,473,362...156,483,324
Ensembl chr 1:156,473,362...156,483,324 		JBrowse link
G As3mt arsenite methyltransferase affects expression EXP Cocaine affects the expression of AS3MT mRNA CTD PMID:20187946 NCBI chr 1:245,595,939...245,628,921
Ensembl chr 1:245,596,108...245,627,872 		JBrowse link
G Asap1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 decreases expression EXP Cocaine results in decreased expression of ASAP1 mRNA CTD PMID:17898221 NCBI chr 7:95,786,130...96,093,111
Ensembl chr 7:95,787,818...96,092,754 		JBrowse link
G Atad1 ATPase family, AAA domain containing 1 increases expression EXP Cocaine results in increased expression of ATAD1 mRNA CTD PMID:17898221 NCBI chr 1:230,544,227...230,610,524
Ensembl chr 1:230,544,047...230,596,548 		JBrowse link
G Atad5 ATPase family, AAA domain containing 5 decreases expression EXP Cocaine results in decreased expression of ATAD5 mRNA CTD PMID:17898221 NCBI chr10:65,070,682...65,118,489
Ensembl chr10:65,070,689...65,117,845 		JBrowse link
G Ate1 arginyltransferase 1 increases expression EXP Cocaine results in increased expression of ATE1 mRNA CTD PMID:17898221 NCBI chr 1:184,961,548...185,081,112
Ensembl chr 1:184,963,562...185,080,908 		JBrowse link
G Atf3 activating transcription factor 3 increases expression
decreases expression		 EXP Cocaine results in increased expression of ATF3 mRNA
Cocaine results in decreased expression of ATF3 mRNA		 CTD PMID:23644055 PMID:27899881 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atf4 activating transcription factor 4 increases expression EXP Cocaine results in increased expression of ATF4; Cocaine results in increased expression of ATF4 mRNA CTD PMID:18593214 PMID:23644055 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Atf6 activating transcription factor 6 affects expression EXP Cocaine affects the expression of ATF6 mRNA CTD PMID:23644055 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177 		JBrowse link
G Atf7 activating transcription factor 7 affects expression ISO Cocaine affects the expression of ATF7 mRNA CTD PMID:15681117 NCBI chr 7:133,660,491...133,750,902
Ensembl chr 7:133,663,294...133,750,848 		JBrowse link
G Atg2b autophagy related 2B affects expression EXP Cocaine affects the expression of ATG2B mRNA CTD PMID:20187946 NCBI chr 6:124,522,283...124,592,412
Ensembl chr 6:124,525,523...124,592,015 		JBrowse link
G Atg4b autophagy related 4B, cysteine peptidase affects expression EXP Cocaine affects the expression of ATG4B mRNA CTD PMID:20187946 NCBI chr 9:94,282,417...94,314,109
Ensembl chr 9:94,282,509...94,314,103 		JBrowse link
G Atm ATM serine/threonine kinase multiple interactions
increases expression		 ISO EHMT2 inhibits the reaction [Cocaine results in increased expression of ATM mRNA] CTD PMID:20056891 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Atp10a ATPase phospholipid transporting 10A (putative) decreases expression EXP Cocaine results in decreased expression of ATP10A mRNA CTD PMID:17898221 PMID:27899881 NCBI chr 1:109,556,760...109,730,440
Ensembl chr 1:109,556,782...109,730,437 		JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 affects expression ISO Cocaine affects the expression of ATP1A1 mRNA CTD PMID:18355967 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837 		JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 increases expression
affects expression		 EXP Cocaine results in increased expression of ATP1A3 mRNA
Cocaine affects the expression of ATP1A3 mRNA		 CTD PMID:16076954 PMID:20187946 NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918 		JBrowse link
G Atp1b2 ATPase Na+/K+ transporting subunit beta 2 increases expression EXP Cocaine results in increased expression of ATP1B2 mRNA CTD PMID:16076954 NCBI chr10:54,318,698...54,324,933
Ensembl chr10:54,318,701...54,324,933 		JBrowse link
G Atp1b3 ATPase Na+/K+ transporting subunit beta 3 increases expression
multiple interactions		 ISO Cocaine results in increased expression of ATP1B3 mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of ATP1B3 mRNA]		 CTD PMID:18355967 NCBI chr 8:96,910,265...96,941,592
Ensembl chr 8:96,910,309...96,941,598 		JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha affects expression ISO Cocaine affects the expression of ATP5F1A protein CTD PMID:19393250 NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794 		JBrowse link
G Atp5f1b ATP synthase F1 subunit beta decreases expression ISO Cocaine results in decreased expression of ATP5F1B protein CTD PMID:17075605 NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273 		JBrowse link
G Atp5f1e ATP synthase F1 subunit epsilon affects expression EXP Cocaine affects the expression of ATP5F1E mRNA CTD PMID:20187946 NCBI chr 3:163,259,072...163,261,974
Ensembl chr 3:163,260,476...163,261,450 		JBrowse link
G Atp5mc3 ATP synthase membrane subunit c locus 3 decreases expression
affects expression		 ISO
EXP		 Cocaine results in decreased expression of ATP5MC3 mRNA
Cocaine affects the expression of ATP5MC3 mRNA		 CTD PMID:12629581 PMID:20187946 NCBI chr 3:58,810,535...58,813,185
Ensembl chr 3:58,810,535...58,814,279 		JBrowse link
G Atp5pb ATP synthase peripheral stalk-membrane subunit b affects expression EXP Cocaine affects the expression of ATP5PB mRNA CTD PMID:20187946 NCBI chr 2:193,424,138...193,435,418
Ensembl chr 2:193,424,047...193,435,418 		JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d affects expression EXP Cocaine affects the expression of ATP5PD mRNA CTD PMID:12358776 NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479 		JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D affects expression EXP Cocaine affects the expression of ATP6V1D mRNA CTD PMID:20187946 NCBI chr 6:97,656,725...97,672,295
Ensembl chr 6:97,656,576...97,672,303 		JBrowse link
G Atp8b2 ATPase phospholipid transporting 8B2 increases expression
multiple interactions		 ISO Cocaine results in increased expression of ATP8B2 mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of ATP8B2 mRNA]		 CTD PMID:18355967 NCBI chr 2:175,378,514...175,402,265
Ensembl chr 2:175,378,517...175,401,883 		JBrowse link
G Atp9b ATPase phospholipid transporting 9B (putative) affects response to substance ISO ATP9B gene SNP affects the susceptibility to Cocaine CTD PMID:18438686 NCBI chr18:74,176,863...74,368,993
Ensembl chr18:74,176,863...74,368,953 		JBrowse link
G Atpaf1 ATP synthase mitochondrial F1 complex assembly factor 1 multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in decreased expression of ATPAF1 mRNA CTD PMID:18355967 NCBI chr 5:129,265,789...129,292,463
Ensembl chr 5:129,266,404...129,293,556 		JBrowse link
G Atrx ATRX, chromatin remodeler increases expression EXP Cocaine results in increased expression of ATRX mRNA CTD PMID:17898221 NCBI chr  X:70,850,981...70,997,330
Ensembl chr  X:70,850,981...70,997,330 		JBrowse link
G Atxn1 ataxin 1 affects expression EXP Cocaine affects the expression of ATXN1 mRNA CTD PMID:20187946 NCBI chr17:18,737,491...19,142,360
Ensembl chr17:18,737,533...19,142,360 		JBrowse link
G Atxn3 ataxin 3 decreases expression ISO Cocaine results in decreased expression of ATXN3 mRNA CTD PMID:12629581 NCBI chr 6:121,072,228...121,107,902
Ensembl chr 6:121,074,448...121,107,902 		JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc-binding decreases expression EXP Cocaine results in decreased expression of AZGP1 mRNA CTD PMID:17898221 NCBI chr12:16,930,990...16,939,333
Ensembl chr12:16,931,024...16,939,091 		JBrowse link
G Baalc BAALC binder of MAP3K1 and KLF4 decreases expression ISO Cocaine results in decreased expression of BAALC mRNA CTD PMID:18355967 NCBI chr 7:69,918,998...69,992,289
Ensembl chr 7:69,918,998...69,992,288 		JBrowse link
G Bach1 BTB domain and CNC homolog 1 increases expression EXP Cocaine results in increased expression of BACH1 mRNA CTD PMID:17898221 NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447 		JBrowse link
G Bach2 BTB domain and CNC homolog 2 affects expression ISO Cocaine affects the expression of BACH2 mRNA CTD PMID:15681117 NCBI chr 5:46,632,338...46,982,676
Ensembl chr 5:46,638,317...46,977,877 		JBrowse link
G Bad BCL2-associated agonist of cell death affects expression ISO Cocaine affects the expression of BAD mRNA CTD PMID:15681117 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bag1 BAG cochaperone 1 affects expression ISO Cocaine affects the expression of BAG1 mRNA CTD PMID:15681117 NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075 		JBrowse link
G Bag3 BAG cochaperone 3 affects expression
increases expression		 ISO
EXP		 Cocaine affects the expression of BAG3 mRNA
Cocaine results in increased expression of BAG3 mRNA		 CTD PMID:15681117 PMID:27899881 NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858 		JBrowse link
G Bambi BMP and activin membrane-bound inhibitor affects expression EXP Cocaine affects the expression of BAMBI mRNA CTD PMID:20187946 NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060 		JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 affects expression EXP Cocaine affects the expression of BASP1 mRNA CTD PMID:20187946 NCBI chr 2:75,816,130...75,863,801
Ensembl chr 2:75,816,122...75,864,043 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
affects expression
increases activity
multiple interactions		 ISO
EXP		 Cocaine results in increased expression of BAX mRNA
Cocaine affects the expression of BAX mRNA
Cocaine results in increased activity of BAX protein
Cocaine results in increased expression of BAX protein
ADCYAP1 protein modified form affects the reaction [Cocaine results in increased expression of BAX protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide affects the reaction [Cocaine results in increased expression of BAX protein]; IL6 protein affects the reaction [Cocaine results in increased expression of BAX protein]; TNF protein affects the reaction [Cocaine results in increased expression of BAX protein]; TNF protein affects the reaction [IL6 protein affects the reaction [Cocaine results in increased expression of BAX protein]]		 CTD PMID:11392460 PMID:15681117 PMID:15685203 PMID:17084983 PMID:17635674 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Baz1b bromodomain adjacent to zinc finger domain, 1B multiple interactions
increases expression		 ISO [SMARCA5 protein co-treated with BAZ1B protein] results in increased susceptibility to Cocaine; Cocaine promotes the reaction [BAZ1B protein binds to SPHKAP gene]; Cocaine results in increased expression of and affects the activity of BAZ1B protein
Cocaine results in increased expression of BAZ1B mRNA		 CTD PMID:27053203 NCBI chr12:21,431,985...21,489,956
Ensembl chr12:21,431,985...21,490,426 		JBrowse link
G Baz2b bromodomain adjacent to zinc finger domain, 2B increases expression EXP Cocaine results in increased expression of BAZ2B mRNA CTD PMID:17898221 NCBI chr 3:44,384,282...44,681,619
Ensembl chr 3:44,385,474...44,592,908 		JBrowse link
G Bcap31 B-cell receptor-associated protein 31 affects expression EXP Cocaine affects the expression of BCAP31 mRNA CTD PMID:20187946 NCBI chr  X:151,397,567...151,429,666
Ensembl chr  X:151,397,576...151,428,506 		JBrowse link
G Bcat1 branched chain amino acid transaminase 1 affects expression EXP Cocaine affects the expression of BCAT1 mRNA CTD PMID:20187946 NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597 		JBrowse link
G Bche butyrylcholinesterase affects metabolic processing
affects degradation
decreases metabolic processing
increases metabolic processing
affects hydrolysis
increases hydrolysis
decreases response to substance
multiple interactions		 ISO BCHE protein affects the metabolism of Cocaine
BCHE protein mutant form affects the degradation of Cocaine
BCHE protein mutant form results in decreased metabolism of Cocaine
BCHE protein results in increased metabolism of Cocaine
BCHE protein affects the hydrolysis of Cocaine
BCHE protein modified form results in increased hydrolysis of Cocaine; BCHE protein mutant form results in increased hydrolysis of Cocaine
BCHE protein mutant form results in decreased susceptibility to Cocaine
BCHE protein mutant form results in increased metabolism of Cocaine; BCHE protein results in increased metabolism of Cocaine
[BCHE protein mutant form results in increased hydrolysis of Cocaine] which results in increased abundance of Benzoic Acid; [BCHE protein mutant form results in increased hydrolysis of Cocaine] which results in increased abundance of ecgonine methyl ester
[BCHE protein mutant form results in increased metabolism of Cocaine] which results in increased chemical synthesis of Benzoic Acid; [BCHE protein mutant form results in increased metabolism of Cocaine] which results in increased chemical synthesis of ecgonine methyl ester		 CTD PMID:572161 PMID:16275916 PMID:17989928 PMID:18514178 PMID:18514640 More... NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Bcl11b BCL11 transcription factor B increases expression ISO Cocaine deficiency results in increased expression of BCL11B mRNA CTD PMID:27126842 NCBI chr 6:126,834,531...126,927,720
Ensembl chr 6:126,834,531...126,928,224 		JBrowse link
G Bcl2 BCL2, apoptosis regulator affects expression
increases expression
decreases expression
multiple interactions
increases phosphorylation		 ISO
EXP		 Cocaine affects the expression of BCL2 mRNA
Cocaine results in increased expression of BCL2 protein
Cocaine results in decreased expression of BCL2 mRNA; Cocaine results in decreased expression of BCL2 protein
6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Cocaine results in increased phosphorylation of BCL2 protein]; 7-(hydroxyimino)cyclopropan(b)chromen-1a-carbxoylic acid ethyl ester inhibits the reaction [Cocaine results in increased phosphorylation of BCL2 protein]; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased phosphorylation of BCL2 protein]; ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate inhibits the reaction [Cocaine results in increased phosphorylation of BCL2 protein]; SCH 23390 inhibits the reaction [Cocaine results in increased phosphorylation of BCL2 protein]
IL6 protein affects the reaction [Cocaine results in decreased expression of BCL2 protein]; PRKCD protein affects the reaction [Cocaine results in decreased expression of BCL2 protein]; rottlerin inhibits the reaction [Cocaine results in decreased expression of BCL2 protein]; TNF protein affects the reaction [Cocaine results in decreased expression of BCL2 protein]; TNF protein affects the reaction [IL6 protein affects the reaction [Cocaine results in decreased expression of BCL2 protein]]		 CTD PMID:11392460 PMID:15365088 PMID:15681117 PMID:15685203 PMID:17084983 More... NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression
multiple interactions
decreases expression		 EXP
ISO		 Cocaine results in increased expression of BCL2L1 mRNA; Cocaine results in increased expression of BCL2L1 mRNA alternative form
IL6 protein affects the reaction [Cocaine results in decreased expression of BCL2L1 protein]; PRKCD protein affects the reaction [Cocaine results in decreased expression of BCL2L1 protein]; rottlerin inhibits the reaction [Cocaine results in decreased expression of BCL2L1 protein]; TNF protein affects the reaction [Cocaine results in decreased expression of BCL2L1 protein]; TNF protein affects the reaction [IL6 protein affects the reaction [Cocaine results in decreased expression of BCL2L1 protein]]		 CTD PMID:16076954 PMID:29673861 PMID:30393195 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bcl2l11 Bcl2-like 11 increases expression EXP Cocaine results in increased expression of BCL2L11 mRNA CTD PMID:16076954 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068 		JBrowse link
G Bdnf brain-derived neurotrophic factor decreases response to substance
increases response to substance
decreases expression
multiple interactions
affects expression
increases expression
decreases activity		 ISO
EXP		 BDNF mRNA results in decreased susceptibility to Cocaine; BDNF protein results in decreased susceptibility to Cocaine
BDNF results in increased susceptibility to Cocaine
Cocaine results in decreased expression of BDNF mRNA; Cocaine results in decreased expression of BDNF protein
(+)-JQ1 compound inhibits the reaction [Cocaine promotes the reaction [BRD4 protein binds to BDNF promoter]]; (+)-JQ1 compound inhibits the reaction [Cocaine results in increased expression of BDNF mRNA]; Cocaine inhibits the reaction [CREB1 protein binds to BDNF promoter]; Cocaine inhibits the reaction [MECP2 protein binds to BDNF promoter]; Cocaine promotes the reaction [BRD4 protein binds to BDNF promoter]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of BDNF mRNA]; Haloperidol inhibits the reaction [Cocaine results in decreased expression of BDNF protein]
BDNF mRNA results in decreased susceptibility to Cocaine; BDNF protein results in decreased susceptibility to Cocaine; BDNF results in decreased susceptibility to Cocaine
BDNF protein inhibits the reaction [Cocaine results in increased abundance of Amino Acids, Peptides, and Proteins]; Cocaine affects the activity of and affects the expression of BDNF protein; Cocaine affects the reaction [CREB1 modified form binds to BDNF promoter]; Cocaine affects the reaction [MECP2 protein affects the expression of BDNF protein]; Cocaine affects the reaction [MECP2 protein binds to and results in decreased activity of BDNF promoter]; Cocaine affects the reaction [MIR212 protein affects the expression of BDNF protein]
Cocaine affects the expression of BDNF exon; Cocaine affects the expression of BDNF mRNA; Cocaine affects the expression of BDNF protein
Cocaine results in increased expression of BDNF protein
Cocaine results in decreased activity of BDNF protein		 CTD PMID:12099907 PMID:14973246 PMID:16423334 PMID:17194538 PMID:17618281 More... NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Begain brain-enriched guanylate kinase-associated affects expression EXP Cocaine affects the expression of BEGAIN mRNA CTD PMID:20187946 NCBI chr 6:127,943,651...127,979,876
Ensembl chr 6:127,943,651...127,979,841 		JBrowse link
G Bhlhe22 basic helix-loop-helix family, member e22 increases expression EXP Cocaine results in increased expression of BHLHE22 mRNA CTD PMID:17898221 NCBI chr 2:100,486,400...100,489,510
Ensembl chr 2:100,486,400...100,489,510 		JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 affects expression EXP Cocaine affects the expression of BHLHE40 mRNA CTD PMID:20187946 NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774 		JBrowse link
G Bid BH3 interacting domain death agonist affects expression ISO Cocaine affects the expression of BID mRNA CTD PMID:15681117 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Bik BCL2-interacting killer affects expression ISO Cocaine affects the expression of BIK mRNA CTD PMID:15681117 NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296 		JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 decreases expression ISO Cocaine results in decreased expression of BMAL1 mRNA CTD PMID:15994025 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231 		JBrowse link
G Bmp2k BMP-2 inducible kinase affects expression EXP Cocaine affects the expression of BMP2K mRNA CTD PMID:20187946 NCBI chr14:12,481,194...12,579,411
Ensembl chr14:12,484,729...12,579,134 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 increases expression EXP Cocaine results in increased expression of BMPR2 mRNA CTD PMID:17898221 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809 		JBrowse link
G Bnip2 BCL2 interacting protein 2 affects expression ISO Cocaine affects the expression of BNIP2 mRNA CTD PMID:15681117 NCBI chr 8:70,640,436...70,661,782
Ensembl chr 8:70,640,445...70,675,590 		JBrowse link
G Bnip3 BCL2 interacting protein 3 affects expression ISO Cocaine affects the expression of BNIP3 mRNA CTD PMID:15681117 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G Bnip3l BCL2 interacting protein 3 like affects expression ISO Cocaine affects the expression of BNIP3L mRNA CTD PMID:15681117 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803 		JBrowse link
G Brd4 bromodomain containing 4 multiple interactions
increases expression		 ISO
EXP		 (+)-JQ1 compound inhibits the reaction [Cocaine promotes the reaction [BRD4 protein binds to BDNF promoter]]; Cocaine promotes the reaction [BRD4 protein binds to BDNF promoter]
Cocaine results in increased expression of BRD4 protein		 CTD PMID:26558777 NCBI chr 7:11,216,446...11,296,029
Ensembl chr 7:11,216,446...11,295,539 		JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin affects expression EXP Cocaine affects the expression of BSCL2 mRNA CTD PMID:20187946 NCBI chr 1:205,731,828...205,743,430
Ensembl chr 1:205,733,872...205,743,421 		JBrowse link
G Bst1 bone marrow stromal cell antigen 1 affects expression EXP Cocaine affects the expression of BST1 mRNA CTD PMID:20187946 NCBI chr14:67,253,706...67,270,203
Ensembl chr14:67,252,998...67,270,180 		JBrowse link
G Btbd9 BTB domain containing 9 increases expression EXP Cocaine results in increased expression of BTBD9 mRNA CTD PMID:17898221 NCBI chr20:8,286,337...8,645,567
Ensembl chr20:8,288,711...8,643,960 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 affects expression EXP Cocaine affects the expression of BTG2 mRNA CTD PMID:20187946 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628 		JBrowse link
G Btk Bruton tyrosine kinase decreases expression EXP Cocaine results in decreased expression of BTK mRNA CTD PMID:17898221 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853 		JBrowse link
G C1qbp complement C1q binding protein decreases expression EXP Cocaine results in decreased expression of C1QBP protein CTD PMID:25100957 NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649 		JBrowse link
G C1qtnf1 C1q and TNF related 1 affects expression EXP Cocaine affects the expression of C1QTNF1 mRNA CTD PMID:20187946 NCBI chr10:103,660,319...103,681,662
Ensembl chr10:103,660,327...103,681,660 		JBrowse link
G C1qtnf4 C1q and TNF related 4 decreases expression EXP Cocaine results in decreased expression of C1QTNF4 mRNA CTD PMID:17898221 NCBI chr 3:76,854,368...76,872,991
Ensembl chr 3:76,857,735...76,874,139 		JBrowse link
G C2cd3 C2 domain containing 3 centriole elongation regulator decreases expression EXP Cocaine results in decreased expression of C2CD3 mRNA CTD PMID:17898221 NCBI chr 1:154,715,151...154,812,955
Ensembl chr 1:154,715,310...154,812,520 		JBrowse link
G C2cd4d C2 calcium-dependent domain containing 4D decreases expression EXP Cocaine results in decreased expression of C2CD4D mRNA CTD PMID:27899881 NCBI chr 2:181,999,778...182,001,941
Ensembl chr 2:181,997,078...182,002,087 		JBrowse link
G C3h11orf96 similar to human chromosome 11 open reading frame 96 increases expression EXP Cocaine results in increased expression of C3H11ORF96 mRNA CTD PMID:27899881 NCBI chr 3:79,920,125...79,921,368
Ensembl chr 3:79,920,129...79,921,523 		JBrowse link
G Cab39l calcium binding protein 39-like multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in increased expression of CAB39L mRNA CTD PMID:18355967 NCBI chr15:33,606,588...33,710,518
Ensembl chr15:33,606,694...33,743,545 		JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D affects response to substance ISO CACNA1D polymorphism affects the susceptibility to Cocaine CTD PMID:28194001 NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215 		JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 affects expression EXP Cocaine affects the expression of CACNB3 mRNA CTD PMID:20187946 NCBI chr 7:129,784,799...129,797,074
Ensembl chr 7:129,783,674...129,797,074 		JBrowse link
G Cald1 caldesmon 1 affects expression EXP Cocaine affects the expression of CALD1 mRNA CTD PMID:20187946 NCBI chr 4:63,265,781...63,446,938
Ensembl chr 4:63,265,942...63,446,932 		JBrowse link
G Calm1 calmodulin 1 decreases expression ISO Cocaine results in decreased expression of CALM1 mRNA CTD PMID:17205118 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227 		JBrowse link
G Calm2 calmodulin 2 decreases expression ISO Cocaine results in decreased expression of CALM2 mRNA CTD PMID:17205118 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287 		JBrowse link
G Calr calreticulin decreases expression
affects expression
multiple interactions		 ISO
EXP		 Cocaine results in decreased expression of CALR mRNA
Cocaine affects the expression of CALR mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of CALR mRNA]		 CTD PMID:18355967 PMID:20187946 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414 		JBrowse link
G Caly calcyon neuron-specific vesicular protein increases expression EXP Cocaine results in increased expression of CALY mRNA CTD PMID:20171207 NCBI chr 1:194,862,671...194,873,861
Ensembl chr 1:194,862,672...194,873,551 		JBrowse link
G Camk1g calcium/calmodulin-dependent protein kinase IG multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in increased expression of CAMK1G mRNA CTD PMID:18355967 NCBI chr13:104,877,909...104,901,658
Ensembl chr13:104,877,910...104,901,556 		JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha affects response to substance
multiple interactions
increases expression		 ISO
EXP		 CAMK2A affects the susceptibility to Cocaine
7-chlorokynurenic acid inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of CAMK2A protein]; Cocaine promotes the reaction [DRD3 protein binds to CAMK2A protein]; Cocaine results in increased phosphorylation of and results in increased activity of CAMK2A protein; KN 93 inhibits the reaction [Cocaine promotes the reaction [DRD3 protein binds to CAMK2A protein]]; Sodium Benzoate promotes the reaction [Cocaine results in increased phosphorylation of and results in increased activity of CAMK2A protein]
Cocaine results in increased expression of CAMK2A protein
Cocaine results in increased expression of and results in increased phosphorylation of CAMK2A protein; Nifedipine inhibits the reaction [Cocaine results in increased expression of and results in increased phosphorylation of CAMK2A protein]		 CTD PMID:14725635 PMID:17609678 PMID:19217379 PMID:28194001 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994 		JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta decreases expression
affects expression		 ISO
EXP		 Cocaine results in decreased expression of CAMK2B mRNA
Cocaine affects the expression of CAMK2B mRNA		 CTD PMID:17205118 PMID:20187946 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994 		JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV increases response to substance
decreases response to substance		 ISO CAMK4 promoter SNP results in increased susceptibility to Cocaine
CAMK4 protein results in decreased susceptibility to Cocaine		 CTD PMID:19001277 NCBI chr18:24,582,988...24,811,918
Ensembl chr18:24,585,269...24,802,487 		JBrowse link
G Cap2 cyclase associated actin cytoskeleton regulatory protein 2 affects expression EXP Cocaine affects the expression of CAP2 mRNA CTD PMID:20187946 NCBI chr17:18,054,234...18,203,453
Ensembl chr17:18,054,431...18,203,373 		JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta decreases expression ISO Cocaine results in decreased expression of CAPZB mRNA CTD PMID:12629581 NCBI chr 5:151,435,600...151,535,409
Ensembl chr 5:151,434,871...151,535,409 		JBrowse link
G Car4 carbonic anhydrase 4 decreases expression EXP Cocaine results in decreased expression of CAR4 mRNA CTD PMID:17898221 NCBI chr10:69,827,945...69,836,501
Ensembl chr10:69,827,945...69,836,501 		JBrowse link
G Card11 caspase recruitment domain family, member 11 decreases expression EXP Cocaine results in decreased expression of CARD11 mRNA CTD PMID:27899881 NCBI chr12:13,621,140...13,758,115
Ensembl chr12:13,621,087...13,758,112 		JBrowse link
G Carm1 coactivator-associated arginine methyltransferase 1 affects expression EXP Cocaine affects the expression of CARM1 mRNA CTD PMID:20187946 NCBI chr 8:20,097,262...20,141,950
Ensembl chr 8:20,097,254...20,147,689 		JBrowse link
G Carnmt1 carnosine N-methyltransferase 1 affects expression EXP Cocaine affects the expression of CARNMT1 mRNA CTD PMID:20187946 NCBI chr 1:216,093,720...216,123,360
Ensembl chr 1:216,093,695...216,121,006 		JBrowse link
G Cartpt CART prepropeptide increases expression
affects expression		 ISO
EXP		 Cocaine results in increased expression of CARTPT mRNA
Cocaine affects the expression of CARTPT mRNA		 CTD PMID:15009677 PMID:17851536 PMID:20187946 NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713 		JBrowse link
G Casp2 caspase 2 increases activity
increases expression		 EXP Cocaine results in increased activity of CASP2 protein
Cocaine results in increased expression of CASP2 mRNA		 CTD PMID:16076954 PMID:16638611 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379 		JBrowse link
G Casp3 caspase 3 increases expression
affects expression
multiple interactions
increases cleavage
increases activity		 ISO
EXP		 Cocaine results in increased expression of CASP3 protein
Cocaine affects the expression of CASP3 mRNA
[Heroin co-treated with Cocaine] results in increased activity of CASP3 protein; Cocaine results in increased cleavage of and results in increased activity of CASP3 protein; Heroin promotes the reaction [Cocaine results in increased activity of CASP3 protein]; SB 203580 inhibits the reaction [Cocaine results in increased activity of CASP3 protein]
Cocaine affects the expression of CASP3 protein
Cocaine results in increased cleavage of CASP3 protein
ADCYAP1 protein modified form affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; GPX1 affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; IL6 protein affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; PRKCD protein affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; rottlerin inhibits the reaction [Cocaine results in increased cleavage of CASP3 protein]; TNF protein affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; TNF protein affects the reaction [IL6 protein affects the reaction [Cocaine results in increased cleavage of CASP3 protein]]		 CTD PMID:10604926 PMID:11392460 PMID:12639677 PMID:14741756 PMID:15365088 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp4 caspase 4 affects expression
decreases expression		 ISO Cocaine affects the expression of CASP4 mRNA
Cocaine results in decreased expression of CASP4 mRNA		 CTD PMID:12629581 PMID:15681117 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
G Casp8 caspase 8 affects expression
increases activity		 ISO
EXP		 Cocaine affects the expression of CASP8 mRNA
Cocaine results in increased activity of CASP8 protein		 CTD PMID:11392460 PMID:15681117 PMID:18974856 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 affects expression
increases expression
multiple interactions
increases activity		 ISO
EXP		 Cocaine affects the expression of CASP9 mRNA
Cocaine results in increased expression of CASP9 protein
Cocaine affects the expression of CASP9 protein
SB 203580 inhibits the reaction [Cocaine results in increased activity of CASP9 protein]		 CTD PMID:10604926 PMID:11392460 PMID:12639677 PMID:15365088 PMID:15681117 More... NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Castor1 cytosolic arginine sensor for mTORC1 subunit 1 affects expression EXP Cocaine affects the expression of CASTOR1 mRNA CTD PMID:20187946 NCBI chr14:79,086,136...79,090,549
Ensembl chr14:79,086,136...79,090,548 		JBrowse link
G Cat catalase decreases activity
increases expression
increases activity		 ISO
EXP		 Cocaine results in decreased activity of CAT protein
Cocaine results in increased expression of CAT protein
Cocaine results in increased activity of CAT protein		 CTD PMID:14576513 PMID:16085363 PMID:29475069 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Catsper2 cation channel, sperm associated 2 increases expression EXP Cocaine results in increased expression of CATSPER2 mRNA CTD PMID:17898221 NCBI chr 3:108,368,654...108,389,380
Ensembl chr 3:108,368,668...108,388,050 		JBrowse link
G Cbln1 cerebellin 1 precursor multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in increased expression of CBLN1 mRNA CTD PMID:18355967 NCBI chr19:19,608,763...19,612,572
Ensembl chr19:19,608,716...19,612,572 		JBrowse link
G Ccdc127 coiled-coil domain containing 127 increases expression EXP Cocaine results in increased expression of CCDC127 mRNA CTD PMID:17898221 NCBI chr 1:28,928,420...28,935,885
Ensembl chr 1:28,928,325...28,935,893 		JBrowse link
G Ccdc174 coiled-coil domain containing 174 affects expression EXP Cocaine affects the expression of CCDC174 mRNA CTD PMID:20187946 NCBI chr 4:124,392,183...124,419,035
Ensembl chr 4:124,392,274...124,419,035 		JBrowse link
G Ccdc73 coiled-coil domain containing 73 decreases expression EXP Cocaine results in decreased expression of CCDC73 mRNA CTD PMID:17898221 NCBI chr 3:91,282,919...91,424,269
Ensembl chr 3:91,282,940...91,424,551 		JBrowse link
G Ccdc88a coiled coil domain containing 88A increases expression EXP Cocaine results in increased expression of CCDC88A mRNA CTD PMID:17898221 NCBI chr14:103,104,091...103,256,112
Ensembl chr14:103,103,513...103,252,368 		JBrowse link
G Ccdc93 coiled-coil domain containing 93 increases expression EXP Cocaine results in increased expression of CCDC93 mRNA CTD PMID:17898221 NCBI chr13:32,607,618...32,675,993
Ensembl chr13:32,607,587...32,676,023 		JBrowse link
G Cckbr cholecystokinin B receptor decreases expression
increases response to substance		 ISO Cocaine results in decreased expression of CCKBR mRNA
CCKBR protein results in increased susceptibility to Cocaine		 CTD PMID:11403953 PMID:18000554 NCBI chr 1:159,771,733...159,781,738
Ensembl chr 1:159,771,733...159,814,881 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases secretion
increases expression
multiple interactions		 ISO
EXP		 Cocaine results in increased secretion of CCL2 protein
Cocaine results in increased expression of CCL2 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; AG 1879 inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; Cocaine promotes the reaction [RELA protein binds to CCL2 promoter]; methyl-beta-cyclodextrin inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; pyrazolanthrone inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; RELA mutant form inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; SC 514 inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; SIGMAR1 mutant form inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; U 0126 inhibits the reaction [Cocaine results in increased expression of CCL2 protein]
Cocaine results in increased expression of CCL2 mRNA; Cocaine results in increased expression of CCL2 protein		 CTD PMID:10065903 PMID:20354174 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases secretion ISO Cocaine results in increased secretion of CCL3 protein CTD PMID:10065903 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression ISO Cocaine results in decreased expression of CCN2 mRNA; Cocaine results in decreased expression of CCN2 protein CTD PMID:18000554 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Ccn3 cellular communication network factor 3 increases expression EXP Cocaine results in increased expression of CCN3 mRNA CTD PMID:17898221 NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019 		JBrowse link
G Ccna2 cyclin A2 decreases expression ISO
EXP		 Cocaine results in decreased expression of CCNA2 mRNA CTD PMID:18593214 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ccnd1 cyclin D1 affects expression EXP Cocaine affects the expression of CCND1 mRNA CTD PMID:20187946 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccnd3 cyclin D3 affects expression EXP Cocaine affects the expression of CCND3 mRNA CTD PMID:20187946 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371 		JBrowse link
G Ccnl1 cyclin L1 increases expression EXP Cocaine results in increased expression of CCNL1 mRNA CTD PMID:16076954 NCBI chr 2:150,184,865...150,199,524
Ensembl chr 2:150,184,798...150,197,368 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 affects expression
increases response to substance		 EXP
ISO		 Cocaine affects the expression of CCR2 mRNA
CCR2 results in increased susceptibility to Cocaine		 CTD PMID:20187946 PMID:20354174 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 increases expression ISO Cocaine results in increased expression of CCR5 protein CTD PMID:16204638 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260 		JBrowse link
G Ccser1 coiled-coil serine-rich protein 1 affects response to substance ISO CCSER1 gene SNP affects the susceptibility to Cocaine CTD PMID:18438686 NCBI chr 4:90,153,873...91,391,441
Ensembl chr 4:90,292,780...91,388,786 		JBrowse link
G Cct2 chaperonin containing TCP1 subunit 2 affects expression EXP Cocaine affects the expression of CCT2 mRNA CTD PMID:20187946 NCBI chr 7:52,692,725...52,705,478
Ensembl chr 7:52,692,725...52,706,944 		JBrowse link
G Ccz1 CCZ1 homolog, vacuolar protein trafficking and biogenesis associated decreases expression ISO Cocaine results in decreased expression of CCZ1 mRNA CTD PMID:12629581 NCBI chr12:10,601,066...10,624,608
Ensembl chr12:10,601,056...10,624,608 		JBrowse link
G Cd180 CD180 molecule decreases expression EXP Cocaine results in decreased expression of CD180 mRNA CTD PMID:27899881 NCBI chr 2:33,855,940...33,870,046
Ensembl chr 2:33,855,991...33,899,936 		JBrowse link
G Cd276 Cd276 molecule affects expression EXP Cocaine affects the expression of CD276 mRNA CTD PMID:20187946 NCBI chr 8:58,937,751...58,968,082
Ensembl chr 8:58,937,751...58,968,380 		JBrowse link
G Cd4 Cd4 molecule multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in decreased expression of CD4 mRNA CTD PMID:18355967 NCBI chr 4:157,668,878...157,695,366 JBrowse link
G Cd44 CD44 molecule decreases expression ISO Cocaine results in decreased expression of CD44 mRNA CTD PMID:18000554 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cd47 Cd47 molecule affects expression EXP Cocaine affects the expression of CD47 mRNA CTD PMID:20187946 NCBI chr11:50,906,052...50,970,000
Ensembl chr11:50,906,177...50,969,425 		JBrowse link
G Cd74 CD74 molecule affects expression EXP Cocaine affects the expression of CD74 mRNA CTD PMID:20187946 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003 		JBrowse link
G Cd81 Cd81 molecule increases response to substance
affects response to substance
increases expression		 ISO
EXP		 CD81 protein results in increased susceptibility to Cocaine
CD81 protein affects the susceptibility to Cocaine
Cocaine results in increased expression of CD81 mRNA		 CTD PMID:11178868 PMID:12113778 PMID:15715673 NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660 		JBrowse link
G Cd93 CD93 molecule decreases expression EXP Cocaine results in decreased expression of CD93 mRNA CTD PMID:17898221 NCBI chr 3:135,891,859...135,898,378
Ensembl chr 3:135,891,859...135,898,378 		JBrowse link
G Cdc14b cell division cycle 14B decreases expression EXP Cocaine results in decreased expression of CDC14B mRNA CTD PMID:17898221 NCBI chr17:844,686...934,787
Ensembl chr17:844,685...933,235 		JBrowse link
G Cdc25a cell division cycle 25A increases expression EXP Cocaine results in increased expression of CDC25A mRNA CTD PMID:17898221 NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701 		JBrowse link
G Cdh1 cadherin 1 decreases expression ISO Cocaine results in decreased expression of CDH1 mRNA CTD PMID:12629581 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdh16 cadherin 16 affects expression EXP Cocaine affects the expression of CDH16 mRNA CTD PMID:20187946 NCBI chr19:360,824...371,008
Ensembl chr19:360,824...371,007 		JBrowse link
G Cdh17 cadherin 17 decreases expression ISO Cocaine results in decreased expression of CDH17 mRNA CTD PMID:12629581 NCBI chr 5:25,262,820...25,314,884
Ensembl chr 5:25,262,758...25,314,884 		JBrowse link
G Cdk18 cyclin-dependent kinase 18 affects expression EXP Cocaine affects the expression of CDK18 mRNA CTD PMID:20187946 NCBI chr13:43,555,597...43,582,210
Ensembl chr13:43,556,748...43,588,525 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 affects expression ISO Cocaine affects the expression of CDK4 mRNA CTD PMID:18355967 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Cdk5 cyclin-dependent kinase 5 affects expression
decreases expression
increases expression		 EXP Cocaine affects the expression of CDK5 mRNA; Cocaine affects the expression of CDK5 protein
Cocaine results in decreased expression of CDK5 protein
Cocaine results in increased expression of CDK5 mRNA; Cocaine results in increased expression of CDK5 protein		 CTD PMID:11268215 PMID:12787079 PMID:16263094 PMID:17339080 PMID:17680995 More... NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112 		JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 multiple interactions
decreases expression
increases expression		 ISO
EXP		 CDK5R1 protein inhibits the reaction [Cocaine affects the expression of FOS mRNA]; CDK5R1 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of CREB1 protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of MAP2K1 protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of MAP2K2 protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of MAPK1 protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of MAPK3 protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of PPP1R1B protein]
Cocaine results in decreased expression of CDK5R1 protein
Cocaine results in increased expression of CDK5R1 mRNA; Cocaine results in increased expression of CDK5R1 protein		 CTD PMID:11268215 PMID:15665076 PMID:16263094 NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP Cocaine results in increased expression of CDKN1A mRNA CTD PMID:27899881 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 affects expression EXP Cocaine affects the expression of CEACAM3 mRNA CTD PMID:20187946 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Cel carboxyl ester lipase increases expression EXP Cocaine results in increased expression of CEL mRNA CTD PMID:27899881 NCBI chr 3:11,883,532...11,891,035
Ensembl chr 3:11,883,532...11,891,035 		JBrowse link
G Ces1d carboxylesterase 1D multiple interactions
affects binding
increases hydrolysis		 ISO CES1 protein results in increased metabolism of [Cocaine co-treated with Ethanol]; Cocaine inhibits the reaction [CES1 protein results in increased chemical synthesis of 6-O-monoacetylmorphine]; Cocaine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-methylumbelliferyl acetate]; Cocaine inhibits the reaction [CES1 protein results in increased hydrolysis of Heroin]
Cocaine binds to CES1 protein
CES1 protein results in increased hydrolysis of Cocaine		 CTD PMID:8930175 PMID:9311626 PMID:12679808 PMID:12773168 PMID:25445008 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Ces2h carboxylesterase 2H multiple interactions
increases hydrolysis
decreases expression		 ISO Cocaine inhibits the reaction [CES2 protein results in increased chemical synthesis of 6-O-monoacetylmorphine]; Cocaine inhibits the reaction [CES2 protein results in increased chemical synthesis of Morphine]; Cocaine inhibits the reaction [CES2 protein results in increased hydrolysis of 6-O-monoacetylmorphine]; Cocaine inhibits the reaction [CES2 protein results in increased hydrolysis of Heroin]
CES2 protein results in increased hydrolysis of Cocaine
Cocaine results in decreased expression of CES2 mRNA		 CTD PMID:8930175 PMID:9169443 PMID:12629581 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830 		JBrowse link
G Cfh complement factor H decreases expression EXP Cocaine results in decreased expression of CFH mRNA CTD PMID:17898221 NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator affects expression ISO Cocaine affects the expression of CFLAR mRNA CTD PMID:15681117 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034 		JBrowse link
G Chat choline O-acetyltransferase increases expression ISO Cocaine results in increased expression of CHAT protein CTD PMID:35597300 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093 		JBrowse link
G Chfr checkpoint with forkhead and ring finger domains affects expression EXP Cocaine affects the expression of CHFR mRNA CTD PMID:20187946 NCBI chr12:46,504,497...46,538,104
Ensembl chr12:46,504,497...46,538,014 		JBrowse link
G Chn1 chimerin 1 affects expression EXP Cocaine affects the expression of CHN1 mRNA CTD PMID:20187946 NCBI chr 3:58,509,822...58,676,462
Ensembl chr 3:58,510,536...58,676,490 		JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 increases expression ISO Cocaine results in increased expression of CHRM1 protein CTD PMID:35597300 NCBI chr 1:205,567,226...205,583,001
Ensembl chr 1:205,567,220...205,582,356 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 increases expression ISO Cocaine results in increased expression of CHRM3 protein CTD PMID:35597300 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278 		JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 affects expression EXP Cocaine affects the expression of CHRM4 mRNA CTD PMID:20187946 NCBI chr 3:77,893,425...77,901,166
Ensembl chr 3:77,893,425...77,901,159 		JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 decreases response to substance
increases expression		 EXP
ISO		 CHRM5 mutant form results in decreased susceptibility to Cocaine
Cocaine results in increased expression of CHRM5 protein		 CTD PMID:20393457 PMID:35597300 NCBI chr 3:99,284,846...99,337,252
Ensembl chr 3:99,284,846...99,337,252 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit multiple interactions EXP Cocaine inhibits the reaction [Nicotine results in increased activity of [CHRNA3 protein binds to CHRNB2 protein]] CTD PMID:10336510 NCBI chr 8:55,401,668...55,415,165
Ensembl chr 8:55,401,702...55,415,165 		JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions EXP Cocaine inhibits the reaction [Nicotine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]] CTD PMID:10336510 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957 		JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit decreases response to substance ISO CHRNA5 gene polymorphism results in decreased susceptibility to Cocaine CTD PMID:18519132 NCBI chr 8:55,369,794...55,398,526
Ensembl chr 8:55,369,794...55,398,146 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions
increases response to substance		 EXP
ISO		 Cocaine inhibits the reaction [Nicotine results in increased activity of [CHRNA3 protein binds to CHRNB2 protein]]; Cocaine inhibits the reaction [Nicotine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]]
CHRNB2 protein results in increased susceptibility to Cocaine		 CTD PMID:10336510 PMID:11282258 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
G Chrne cholinergic receptor nicotinic epsilon subunit increases expression EXP Cocaine results in increased expression of CHRNE mRNA CTD PMID:27899881 NCBI chr10:55,331,211...55,339,923
Ensembl chr10:55,331,212...55,335,530 		JBrowse link
G Chtf8 chromosome transmission fidelity factor 8 decreases expression EXP Cocaine results in decreased expression of CHTF8 mRNA CTD PMID:17898221 NCBI chr19:34,782,005...34,792,306
Ensembl chr19:34,781,856...34,792,578 		JBrowse link
G Churc1 churchill domain containing 1 decreases expression ISO Cocaine results in decreased expression of CHURC1 mRNA CTD PMID:15009677 PMID:16710320 NCBI chr 6:95,464,488...95,485,208
Ensembl chr 6:95,470,683...95,619,586 		JBrowse link
G Ciao1 cytosolic iron-sulfur assembly component 1 affects expression EXP Cocaine affects the expression of CIAO1 mRNA CTD PMID:20187946 NCBI chr 3:114,458,671...114,465,928
Ensembl chr 3:114,458,655...114,467,009 		JBrowse link
G Cidea cell death-inducing DFFA-like effector a affects expression ISO Cocaine affects the expression of CIDEA mRNA CTD PMID:15681117 NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481 		JBrowse link
G Cideb cell death-inducing DFFA-like effector b affects expression ISO Cocaine affects the expression of CIDEB mRNA CTD PMID:15681117 NCBI chr15:29,252,208...29,256,482
Ensembl chr15:29,252,213...29,256,605 		JBrowse link
G Cisd1 CDGSH iron sulfur domain 1 increases expression EXP Cocaine results in increased expression of CISD1 protein CTD PMID:25100957 NCBI chr20:17,255,302...17,268,688
Ensembl chr20:17,255,151...17,284,924 		JBrowse link
G Cisd2 CDGSH iron sulfur domain 2 increases expression EXP Cocaine results in increased expression of CISD2 mRNA CTD PMID:17898221 NCBI chr 2:223,828,937...223,853,768
Ensembl chr 2:223,828,937...223,868,946 		JBrowse link
G Cited4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 decreases expression EXP Cocaine results in decreased expression of CITED4 mRNA CTD PMID:27899881 NCBI chr 5:134,246,936...134,247,827
Ensembl chr 5:134,246,682...134,248,135 		JBrowse link
G Ckb creatine kinase B multiple interactions ISO Cocaine results in increased secretion of [CKB protein binds to CKM protein] CTD PMID:12359538 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315 		JBrowse link
G Ckm creatine kinase, M-type multiple interactions ISO Cocaine results in increased secretion of [CKB protein binds to CKM protein] CTD PMID:12359538 NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720 		JBrowse link
G Ckmt1 creatine kinase, mitochondrial 1 affects expression EXP Cocaine affects the expression of CKMT1 mRNA CTD PMID:20187946 NCBI chr 3:108,329,859...108,335,760
Ensembl chr 3:108,330,705...108,335,758 		JBrowse link
G Clcn7 chloride voltage-gated channel 7 affects expression EXP Cocaine affects the expression of CLCN7 mRNA CTD PMID:20187946 NCBI chr10:14,151,758...14,177,130
Ensembl chr10:14,151,758...14,177,130 		JBrowse link
G Cldn11 claudin 11 decreases expression ISO Cocaine results in decreased expression of CLDN11 mRNA CTD PMID:18357522 NCBI chr 2:112,207,745...112,221,050
Ensembl chr 2:112,207,745...112,221,050 		JBrowse link
G Clec4f C-type lectin domain family 4, member F affects expression EXP Cocaine affects the expression of CLEC4F mRNA CTD PMID:20187946 NCBI chr 4:116,129,023...116,138,744
Ensembl chr 4:116,129,023...116,138,775 		JBrowse link
G Clic1 chloride intracellular channel 1 decreases expression ISO Cocaine results in decreased expression of CLIC1 mRNA CTD PMID:18000554 NCBI chr20:3,764,867...3,773,711
Ensembl chr20:3,761,461...3,773,712 		JBrowse link
G Clip1 CAP-GLY domain containing linker protein 1 increases expression ISO Cocaine results in increased expression of CLIP1 mRNA CTD PMID:18000554 NCBI chr12:32,910,932...33,017,891
Ensembl chr12:32,910,977...33,017,884 		JBrowse link
G Clk1 CDC-like kinase 1 increases expression
multiple interactions		 ISO Cocaine results in increased expression of CLK1 mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of CLK1 mRNA]		 CTD PMID:18355967 NCBI chr 9:59,947,774...59,959,002
Ensembl chr 9:59,947,764...59,957,000 		JBrowse link
G Clk4 CDC-like kinase 4 increases expression ISO Cocaine results in increased expression of CLK4 mRNA CTD PMID:20056891 NCBI chr10:35,523,382...35,541,387
Ensembl chr10:35,524,755...35,541,352 		JBrowse link
G Clock clock circadian regulator increases expression ISO Cocaine results in increased expression of CLOCK mRNA CTD PMID:15994025 NCBI chr14:31,908,542...31,992,673
Ensembl chr14:31,908,566...31,990,400 		JBrowse link
G Cltb clathrin, light chain B decreases expression ISO Cocaine results in decreased expression of CLTB mRNA CTD PMID:12629581 PMID:15009677 NCBI chr17:10,001,512...10,019,201
Ensembl chr17:10,001,513...10,019,169 		JBrowse link
G Clybl citramalyl-CoA lyase increases expression EXP Cocaine results in increased expression of CLYBL protein CTD PMID:25100957 NCBI chr15:99,283,644...99,505,697
Ensembl chr15:99,283,650...99,505,695 		JBrowse link
G Cnbd2 cyclic nucleotide binding domain containing 2 increases expression EXP Cocaine results in increased expression of CNBD2 mRNA CTD PMID:17898221 NCBI chr 3:144,819,166...144,884,825
Ensembl chr 3:144,819,195...144,901,583 		JBrowse link
G Cnksr2 connector enhancer of kinase suppressor of Ras 2 increases expression ISO Cocaine results in increased expression of CNKSR2 mRNA CTD PMID:15009677 NCBI chr  X:36,908,135...37,148,337
Ensembl chr  X:36,907,850...37,150,555 		JBrowse link
G Cnr1 cannabinoid receptor 1 affects response to substance
multiple interactions
decreases response to substance
increases activity		 ISO CNR1 gene polymorphism affects the susceptibility to Cocaine; CNR1 gene SNP affects the susceptibility to Cocaine; CNR1 polymorphism affects the susceptibility to Cocaine
CNR1 gene mutant form inhibits the reaction [Cocaine results in increased phosphorylation of PPP1R1B protein]; CNR1 mutant form inhibits the reaction [Cocaine results in increased expression of FOS protein]; CNR1 mutant form inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CNR1 mutant form inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein]
CNR1 mutant form results in decreased susceptibility to Cocaine
Cocaine results in increased activity of CNR1 protein		 CTD PMID:9106242 PMID:16314880 PMID:17596442 PMID:19052543 PMID:20554863 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Cnr2 cannabinoid receptor 2 increases expression ISO Cocaine results in increased expression of CNR2 mRNA CTD PMID:18286196 NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548 		JBrowse link
G Cobll1 cordon-bleu WH2 repeat protein-like 1 increases expression ISO Cocaine results in increased expression of COBLL1 mRNA CTD PMID:27506785 NCBI chr 3:49,753,260...49,915,168
Ensembl chr 3:49,753,262...49,915,194 		JBrowse link
G Coil coilin affects expression EXP Cocaine affects the expression of COIL mRNA CTD PMID:20187946 NCBI chr10:73,789,077...73,810,378
Ensembl chr10:73,789,488...73,810,393 		JBrowse link
G Col15a1 collagen type XV alpha 1 chain affects expression EXP Cocaine affects the expression of COL15A1 mRNA CTD PMID:20187946 NCBI chr 5:61,501,963...61,607,591
Ensembl chr 5:61,501,963...61,607,591 		JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression EXP Cocaine results in increased expression of COL1A1 mRNA CTD PMID:9455993 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col3a1 collagen type III alpha 1 chain increases expression EXP Cocaine results in increased expression of COL3A1 mRNA CTD PMID:9455993 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547 		JBrowse link
G Coq6 coenzyme Q6 monooxygenase affects expression EXP Cocaine affects the expression of COQ6 mRNA CTD PMID:20187946 NCBI chr 6:104,007,814...104,019,888
Ensembl chr 6:104,007,872...104,024,657 		JBrowse link
G Coro7 coronin 7 multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in decreased expression of CORO7 mRNA CTD PMID:18355967 NCBI chr10:10,880,299...10,941,001
Ensembl chr10:10,885,196...10,941,001 		JBrowse link
G Cox20 cytochrome c oxidase assembly factor COX20 decreases expression EXP Cocaine results in decreased expression of COX20 mRNA CTD PMID:17898221 NCBI chr13:90,065,900...90,075,386 JBrowse link
G Cox5a cytochrome c oxidase subunit 5A affects expression EXP Cocaine affects the expression of COX5A mRNA CTD PMID:20187946 NCBI chr 8:57,922,374...57,933,781
Ensembl chr 8:57,922,290...57,933,781 		JBrowse link
G Cox6a1 cytochrome c oxidase subunit 6A1 affects expression
increases expression		 EXP Cocaine affects the expression of COX6A1 mRNA
Cocaine results in increased expression of COX6A1 protein		 CTD PMID:20187946 PMID:25100957 NCBI chr12:41,261,983...41,265,037
Ensembl chr12:41,261,967...41,265,041 		JBrowse link
G Cox6c cytochrome c oxidase subunit 6C decreases expression ISO Cocaine results in decreased expression of COX6C mRNA CTD PMID:12629581 NCBI chr 7:67,129,265...67,142,001
Ensembl chr 7:67,111,024...67,141,963 		JBrowse link
G Cox7b cytochrome c oxidase subunit 7B affects expression EXP Cocaine affects the expression of COX7B mRNA CTD PMID:20187946 NCBI chr  X:71,083,486...71,089,733
Ensembl chr  X:71,083,456...71,089,732 		JBrowse link
G Cox8a cytochrome c oxidase subunit 8A affects expression EXP Cocaine affects the expression of COX8A mRNA CTD PMID:20187946 NCBI chr 1:204,402,118...204,404,439 JBrowse link
G Cplx1 complexin 1 affects expression EXP Cocaine affects the expression of CPLX1 mRNA CTD PMID:20187946 NCBI chr14:1,184,677...1,216,392 JBrowse link
G Cpne8 copine 8 increases expression EXP Cocaine results in increased expression of CPNE8 mRNA CTD PMID:17898221 NCBI chr 7:121,615,293...121,789,507
Ensembl chr 7:121,615,294...121,790,377 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 affects expression
increases expression
multiple interactions
affects phosphorylation
increases phosphorylation		 EXP
ISO		 Cocaine affects the expression of CREB1 mRNA
Cocaine results in increased expression of CREB1 protein
Betaxolol affects the reaction [Cocaine affects the phosphorylation of CREB1 protein]; Cocaine affects the reaction [CREB1 modified form binds to BDNF promoter]; Cocaine promotes the reaction [RPS6KA1 protein binds to CREB1 protein]; Cocaine results in increased phosphorylation of and results in increased activity of CREB1 protein; U 0126 inhibits the reaction [Cocaine results in increased phosphorylation of CREB1 protein]
CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of CREB1 protein]; Cocaine inhibits the reaction [CREB1 protein binds to BDNF promoter]; N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine inhibits the reaction [Cocaine results in increased expression of CREB1 protein]; RPS6KA3 gene mutant form inhibits the reaction [Cocaine results in increased phosphorylation of CREB1 protein]; SL 327 inhibits the reaction [Cocaine results in increased phosphorylation of CREB1 protein]
cocaine increases phosphorylation of Creb1 protein in nucleus accumbens		 CTD
RGD		 PMID:12595601 PMID:15470197 PMID:15665076 PMID:16219028 PMID:16339038 More... RGD:401900166 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Crebbp CREB binding protein increases expression EXP Cocaine results in increased expression of CREBBP mRNA CTD PMID:17898221 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888 		JBrowse link
G Crebrf CREB3 regulatory factor increases expression EXP Cocaine results in increased expression of CREBRF mRNA CTD PMID:17898221 NCBI chr10:16,399,170...16,479,650
Ensembl chr10:16,404,596...16,461,999 		JBrowse link
G Crem cAMP responsive element modulator affects expression
increases expression		 ISO
EXP		 Cocaine affects the expression of CREM mRNA
Cocaine results in increased expression of CREM mRNA		 CTD PMID:18355967 PMID:27899881 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989 		JBrowse link
G Crh corticotropin releasing hormone multiple interactions
affects expression		 EXP Betaxolol affects the reaction [Cocaine affects the expression of CRH mRNA]; Cocaine affects the reaction [CRH protein affects the secretion of Excitatory Amino Acid Agents]; SCH 23390 affects the reaction [Cocaine affects the expression of CRH mRNA]
Cocaine affects the expression of CRH mRNA; Cocaine affects the expression of CRH protein		 CTD PMID:7796157 PMID:11597771 PMID:12782395 PMID:15930388 PMID:18596687 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Crhbp corticotropin releasing hormone binding protein increases expression EXP Cocaine results in increased expression of CRHBP mRNA CTD PMID:27899881 NCBI chr 2:26,692,403...26,704,710
Ensembl chr 2:26,692,403...26,704,710 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 increases expression EXP Cocaine results in increased expression of CRHR1 protein CTD PMID:17079348 NCBI chr10:89,040,186...89,083,481
Ensembl chr10:89,040,203...89,083,481 		JBrowse link
G Crip2 cysteine-rich protein 2 affects expression EXP Cocaine affects the expression of CRIP2 mRNA CTD PMID:20187946 NCBI chr 6:132,221,120...132,226,066
Ensembl chr 6:132,221,082...132,226,065 		JBrowse link
G Crispld1 cysteine-rich secretory protein LCCL domain containing 1 decreases expression EXP Cocaine results in decreased expression of CRISPLD1 mRNA CTD PMID:27899881 NCBI chr 5:1,267,347...1,314,926
Ensembl chr 5:1,274,647...1,314,926 		JBrowse link
G Crp C-reactive protein increases expression ISO Cocaine results in increased expression of CRP protein CTD PMID:11988210 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Crtac1 cartilage acidic protein 1 affects expression EXP Cocaine affects the expression of CRTAC1 mRNA CTD PMID:20187946 NCBI chr 1:241,091,679...241,233,677
Ensembl chr 1:241,078,864...241,233,421 		JBrowse link
G Crtc1 CREB regulated transcription coactivator 1 multiple interactions EXP [[Cocaine results in increased expression of MIR212 mRNA] which results in increased activity of RAF1 protein] which results in increased expression of CRTC1 protein CTD PMID:20613834 NCBI chr16:18,988,197...19,046,914
Ensembl chr16:18,988,250...19,043,381 		JBrowse link
G Cry1 cryptochrome circadian regulator 1 decreases expression ISO Cocaine results in decreased expression of CRY1 mRNA CTD PMID:15994025 NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091 		JBrowse link
G Cry2 cryptochrome circadian regulator 2 decreases expression ISO Cocaine results in decreased expression of CRY2 mRNA CTD PMID:15994025 NCBI chr 3:78,374,995...78,405,001
Ensembl chr 3:78,374,995...78,404,965 		JBrowse link
G Cryab crystallin, alpha B decreases expression
increases expression		 ISO
EXP		 Cocaine results in decreased expression of CRYAB mRNA
Cocaine results in increased expression of CRYAB mRNA		 CTD PMID:15009677 PMID:27899881 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157 		JBrowse link
G Crybb2 crystallin, beta B2 decreases expression ISO Cocaine results in decreased expression of CRYBB2 mRNA CTD PMID:15009677 NCBI chr12:43,569,747...43,579,671
Ensembl chr12:43,569,747...43,579,671 		JBrowse link
G Csad cysteine sulfinic acid decarboxylase affects expression
decreases expression		 EXP Cocaine affects the expression of CSAD mRNA
Cocaine results in decreased expression of CSAD protein		 CTD PMID:20187946 PMID:25100957 NCBI chr 7:133,308,571...133,337,914
Ensembl chr 7:133,308,574...133,337,615 		JBrowse link
G Csf2ra colony stimulating factor 2 receptor subunit alpha decreases expression EXP Cocaine results in decreased expression of CSF2RA mRNA CTD PMID:17898221 NCBI chr14:98,089...103,261
Ensembl chr14:89,172...103,128 		JBrowse link
G Csn3 casein kappa affects expression EXP Cocaine affects the expression of CSN3 mRNA CTD PMID:20187946 NCBI chr14:20,154,032...20,160,585
Ensembl chr14:20,154,032...20,160,587 		JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 decreases expression EXP Cocaine results in decreased expression of CSNK2A1 mRNA CTD PMID:12117546 NCBI chr 3:140,709,984...140,756,757
Ensembl chr 3:140,709,991...140,756,696 		JBrowse link
G Cspg5 chondroitin sulfate proteoglycan 5 affects expression EXP Cocaine affects the expression of CSPG5 mRNA; Cocaine affects the expression of CSPG5 protein CTD PMID:12358776 NCBI chr 8:110,220,506...110,234,766
Ensembl chr 8:110,220,653...110,234,758 		JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 decreases expression ISO Cocaine results in decreased expression of CSRP2 mRNA CTD PMID:18000554 NCBI chr 7:46,349,109...46,367,743
Ensembl chr 7:46,348,686...46,367,745 		JBrowse link
G Ctdnep1 CTD nuclear envelope phosphatase 1 affects expression EXP Cocaine affects the expression of CTDNEP1 mRNA CTD PMID:20187946 NCBI chr10:54,704,367...54,713,781
Ensembl chr10:54,704,148...54,713,781 		JBrowse link
G Ctnnb1 catenin beta 1 affects expression
multiple interactions		 EXP Cocaine affects the expression of CTNNB1 mRNA
Cocaine deficiency promotes the reaction [SMARCA4 protein binds to CTNNB1 promoter]		 CTD PMID:20187946 PMID:27422367 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Ctnnbip1 catenin, beta-interacting protein 1 decreases expression ISO Cocaine results in decreased expression of CTNNBIP1 mRNA CTD PMID:18000554 NCBI chr 5:159,961,961...160,010,942
Ensembl chr 5:159,961,928...160,010,939 		JBrowse link
G Ctnnd2 catenin delta 2 decreases expression
increases expression		 ISO
EXP		 Cocaine results in decreased expression of CTNND2 mRNA
Cocaine results in increased expression of CTNND2 mRNA		 CTD PMID:12629581 PMID:16076954 NCBI chr 2:81,168,525...82,016,495
Ensembl chr 2:81,167,117...82,015,764 		JBrowse link
G Ctrl chymotrypsin-like affects expression
increases expression		 EXP Cocaine affects the expression of CTRL mRNA
Cocaine results in increased expression of CTRL mRNA		 CTD PMID:20187946 PMID:27899881 NCBI chr19:33,827,279...33,829,129
Ensembl chr19:33,827,229...33,833,626 		JBrowse link
G Ctsb cathepsin B affects expression
increases expression
multiple interactions		 ISO Cocaine affects the expression of CTSB mRNA
Cocaine results in increased expression of CTSB mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of CTSB mRNA]		 CTD PMID:15681117 PMID:18355967 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500 		JBrowse link
G Ctsd cathepsin D affects expression
increases expression		 ISO
EXP		 Cocaine affects the expression of CTSD mRNA
Cocaine results in increased expression of CTSD protein		 CTD PMID:15681117 PMID:25100957 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488 		JBrowse link
G Cuedc1 CUE domain containing 1 multiple interactions ISO HDAC5 affects the reaction [Cocaine affects the expression of CUEDC1 mRNA] CTD PMID:17988634 NCBI chr10:72,892,637...72,986,546
Ensembl chr10:72,892,637...72,986,542 		JBrowse link
G Cul4b cullin 4B increases expression ISO Cocaine results in increased expression of CUL4B mRNA CTD PMID:15009677 NCBI chr  X:117,287,481...117,326,688
Ensembl chr  X:117,287,484...117,326,688 		JBrowse link
G Cwf19l2 CWF19 like cell cycle control factor 2 increases expression EXP Cocaine results in increased expression of CWF19L2 mRNA CTD PMID:17898221 NCBI chr 6:290,148...356,636
Ensembl chr 6:281,685...356,604 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression EXP Cocaine results in increased expression of CX3CL1 mRNA CTD PMID:16076954 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases secretion ISO Cocaine results in increased secretion of CXCL10 protein CTD PMID:10065903 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 decreases expression EXP Cocaine results in decreased expression of CXCL9 mRNA CTD PMID:17898221 NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO Cocaine results in increased expression of CXCR4 protein CTD PMID:16204638 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Cxxc5 CXXC finger protein 5 affects expression EXP Cocaine affects the expression of CXXC5 mRNA CTD PMID:20187946 NCBI chr18:27,427,591...27,458,579
Ensembl chr18:27,427,230...27,458,673 		JBrowse link
G Cyba cytochrome b-245 alpha chain increases expression ISO Cocaine results in increased expression of CYBA protein CTD PMID:18952886 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721 		JBrowse link
G Cybb cytochrome b-245 beta chain increases expression
increases response to substance		 ISO Cocaine results in increased expression of CYBB protein
CYBB results in increased susceptibility to Cocaine		 CTD PMID:18952886 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586 		JBrowse link
G Cyc1 cytochrome c-1 decreases expression ISO Cocaine results in decreased expression of CYC1 mRNA CTD PMID:12629581 NCBI chr 7:108,067,106...108,069,483
Ensembl chr 7:108,067,115...108,069,479 		JBrowse link
G Cycs cytochrome c, somatic multiple interactions
affects expression		 EXP
ISO		 Minocycline inhibits the reaction [Cocaine results in increased secretion of CYCS protein]
Cocaine affects the expression of CYCS mRNA		 CTD PMID:15681117 PMID:21424555 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Cygb cytoglobin decreases expression EXP Cocaine results in decreased expression of CYGB protein CTD PMID:25100957 NCBI chr10:101,877,675...101,887,442
Ensembl chr10:101,877,676...101,887,442 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases expression EXP Cocaine results in decreased expression of CYP19A1 mRNA CTD PMID:27899881 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression		 ISO Cimetidine inhibits the reaction [Cocaine results in increased expression of CYP1A1 protein]; Metyrapone inhibits the reaction [Cocaine results in increased expression of CYP1A1 protein] CTD PMID:11856816 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 affects expression EXP Cocaine affects the expression of CYP26A1 mRNA CTD PMID:20187946 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204 		JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 decreases response to substance EXP CYP26B1 protein results in decreased susceptibility to Cocaine CTD PMID:27899881 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628 		JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases expression ISO Cocaine results in decreased expression of CYP2C8 mRNA; Cocaine results in decreased expression of CYP2C8 protein CTD PMID:16188404
G Cyp2j10 cytochrome P450, family 2, subfamily j, polypeptide 10 decreases expression EXP Cocaine results in decreased expression of CYP2J10 mRNA CTD PMID:27899881 NCBI chr 5:110,960,319...110,995,220
Ensembl chr 5:110,960,317...110,995,115 		JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 increases expression
multiple interactions		 ISO Cocaine results in increased expression of CYP2J2 protein
Cimetidine inhibits the reaction [Cocaine results in increased expression of CYP2J2 protein]; Metyrapone inhibits the reaction [Cocaine results in increased expression of CYP2J2 protein]		 CTD PMID:11856816 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 affects expression EXP Cocaine affects the expression of CYP3A23-3A1 mRNA CTD PMID:20187946 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030 		JBrowse link
G Cyp51 cytochrome P450, family 51 decreases expression ISO Cocaine results in decreased expression of CYP51 mRNA CTD PMID:12629581 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410 		JBrowse link
G Cyss cystatin S affects expression EXP Cocaine affects the expression of CYSS mRNA CTD PMID:20187946 NCBI chr 3:137,432,049...137,436,654
Ensembl chr 3:137,432,049...137,436,610 		JBrowse link
G Dab2ip DAB2 interacting protein decreases expression EXP Cocaine results in decreased expression of DAB2IP mRNA CTD PMID:17898221 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280 		JBrowse link
G Dazap1 DAZ associated protein 1 affects expression EXP Cocaine affects the expression of DAZAP1 mRNA CTD PMID:20187946 NCBI chr 7:9,423,673...9,448,116
Ensembl chr 7:9,424,178...9,538,818 		JBrowse link
G Dbh dopamine beta-hydroxylase increases response to substance
decreases response to substance		 ISO DBH gene polymorphism results in increased susceptibility to Cocaine
DBH gene mutant form results in decreased susceptibility to Cocaine		 CTD PMID:10673769 PMID:12555232 PMID:18083142 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
G Dbn1 drebrin 1 multiple interactions EXP Cocaine deficiency promotes the reaction [SMARCA4 protein binds to DBN1 promoter] CTD PMID:27422367 NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984 		JBrowse link
G Dcaf8 DDB1 and CUL4 associated factor 8 affects expression EXP Cocaine affects the expression of DCAF8 mRNA CTD PMID:20187946 NCBI chr13:84,609,838...84,667,025
Ensembl chr13:84,610,248...84,669,726 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 affects expression
increases expression		 ISO
EXP		 Cocaine affects the expression of DDIT3 mRNA
Cocaine results in increased expression of DDIT3 mRNA		 CTD PMID:15681117 PMID:20187946 PMID:23644055 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 decreases expression EXP Cocaine results in decreased expression of DDR2 mRNA CTD PMID:17898221 NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363 		JBrowse link
G Ddx41 DEAD-box helicase 41 decreases expression ISO Cocaine results in decreased expression of DDX41 mRNA CTD PMID:18000554 NCBI chr17:9,102,926...9,108,415
Ensembl chr17:9,103,010...9,108,415 		JBrowse link
G Ddx50 DExD-box helicase 50 affects expression EXP Cocaine affects the expression of DDX50 mRNA CTD PMID:20187946 NCBI chr20:30,561,623...30,591,324
Ensembl chr20:30,560,544...30,591,152 		JBrowse link
G Ddx6 DEAD-box helicase 6 increases expression EXP Cocaine results in increased expression of DDX6 mRNA CTD PMID:17898221 NCBI chr 8:44,931,127...44,967,773
Ensembl chr 8:44,931,974...44,964,405 		JBrowse link
G Deaf1 DEAF1 transcription factor decreases expression ISO Cocaine results in decreased expression of DEAF1 mRNA CTD PMID:15009677 PMID:16710320 NCBI chr 1:196,401,857...196,435,541
Ensembl chr 1:196,401,857...196,435,541 		JBrowse link
G Dhh desert hedgehog signaling molecule affects expression EXP Cocaine affects the expression of DHH mRNA CTD PMID:20187946 NCBI chr 7:130,050,910...130,056,406
Ensembl chr 7:130,050,910...130,056,406 		JBrowse link
G Dhx30 DExH-box helicase 30 affects expression EXP Cocaine affects the expression of DHX30 mRNA CTD PMID:20187946 NCBI chr 8:110,064,751...110,096,954
Ensembl chr 8:110,064,752...110,097,381 		JBrowse link
G Dipk1b divergent protein kinase domain 1B affects expression EXP Cocaine affects the expression of DIPK1B mRNA CTD PMID:20187946 NCBI chr 3:9,455,914...9,464,169
Ensembl chr 3:9,456,409...9,464,161 		JBrowse link
G Dlg2 discs large MAGUK scaffold protein 2 increases expression EXP Cocaine results in increased expression of DLG2 protein CTD PMID:25100957 NCBI chr 1:144,451,653...146,503,949
Ensembl chr 1:144,451,472...146,499,475 		JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 affects expression
decreases expression
decreases response to substance
multiple interactions
increases expression		 EXP
ISO		 Cocaine affects the expression of DLG4 mRNA; Cocaine affects the expression of DLG4 protein
Cocaine results in decreased expression of DLG4 mRNA
DLG4 protein results in decreased susceptibility to Cocaine
ILK mutant form inhibits the reaction [Cocaine results in increased expression of DLG4 protein]		 CTD PMID:14980210 PMID:19629758 PMID:20187946 PMID:20534846 PMID:20600170 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153 		JBrowse link
G Dlk2 delta like non-canonical Notch ligand 2 decreases expression
multiple interactions		 ISO Cocaine results in decreased expression of DLK2 mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of DLK2 mRNA]		 CTD PMID:18355967 NCBI chr 9:14,677,102...14,681,584
Ensembl chr 9:14,676,562...14,681,594 		JBrowse link
G Dnah8 dynein, axonemal, heavy chain 8 affects response to substance ISO DNAH8 gene SNP affects the susceptibility to Cocaine CTD PMID:18438686 NCBI chr20:8,692,939...8,946,780
Ensembl chr20:8,692,963...8,946,772 		JBrowse link
G Dnm1 dynamin 1 affects expression EXP Cocaine affects the expression of DNM1 mRNA CTD PMID:20187946 NCBI chr 3:15,604,782...15,648,654
Ensembl chr 3:15,604,784...15,648,538 		JBrowse link
G Dnm1l dynamin 1-like multiple interactions
increases phosphorylation		 EXP
ISO		 [Cocaine co-treated with Cocaine deficiency] promotes the reaction [RUNX2 protein binds to DNM1L promoter]
Cocaine results in increased phosphorylation of DNM1L protein		 CTD PMID:30158054 PMID:31494168 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482 		JBrowse link
G Dnm2 dynamin 2 affects expression EXP Cocaine affects the expression of DNM2 mRNA CTD PMID:20187946 NCBI chr 8:19,978,313...20,060,162
Ensembl chr 8:19,978,400...20,060,157 		JBrowse link
G Dnm3 dynamin 3 affects expression EXP Cocaine affects the expression of DNM3 mRNA CTD PMID:20187946 NCBI chr13:74,359,043...74,838,135
Ensembl chr13:74,359,213...74,838,108 		JBrowse link
G Dnmbp dynamin binding protein decreases expression EXP Cocaine results in decreased expression of DNMBP mRNA CTD PMID:17898221 NCBI chr 1:242,736,189...242,829,431
Ensembl chr 1:242,736,189...242,802,604 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta decreases expression
multiple interactions		 ISO Cocaine results in decreased expression of DNMT3B mRNA; Cocaine results in decreased expression of DNMT3B protein
Methionine inhibits the reaction [Cocaine results in decreased expression of DNMT3B mRNA]; Methionine inhibits the reaction [Cocaine results in decreased expression of DNMT3B protein]		 CTD PMID:22438930 NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124 		JBrowse link
G Dnph1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 decreases expression ISO Cocaine results in decreased expression of DNPH1 mRNA CTD PMID:15009677 PMID:16710320 NCBI chr 9:14,481,296...14,484,034
Ensembl chr 9:14,481,066...14,484,022 		JBrowse link
G Dpf2 double PHD fingers 2 increases expression ISO Cocaine results in increased expression of DPF2 mRNA CTD PMID:18000554 NCBI chr 1:203,183,674...203,199,037
Ensembl chr 1:203,183,686...203,198,983 		JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 multiple interactions EXP [Cocaine affects the activity of PRKACA protein] which affects the phosphorylation of DPYSL2 protein CTD PMID:19457111 NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829 		JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 affects expression EXP Cocaine affects the expression of DPYSL3 mRNA CTD PMID:20187946 NCBI chr18:35,374,427...35,480,228
Ensembl chr18:35,377,181...35,480,157 		JBrowse link
G Drd1 dopamine receptor D1 multiple interactions
decreases response to substance
increases response to substance
affects expression
affects response to substance
decreases expression
increases expression		 ISO
EXP		 1-propyl-5-(3-p-tolylisoxazol-5-yl)-1,2,3,6-tetrahydropyridine inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]]; 1-propyl-5-(3-p-tolylisoxazol-5-yl)-1,2,3,6-tetrahydropyridine inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]]; [Cocaine binds to SIGMAR1 protein] affects the folding of [SIGMAR1 protein binds to DRD1 protein]; Cocaine affects the localization of [DRD1 protein binds to SIGMAR1 protein]; Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Cocaine promotes the reaction [DRD1 protein binds to SIGMAR1 protein]; SCH 23390 inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]]; SCH 23390 inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]]
[anhydroecgonine methyl ester co-treated with Cocaine] results in decreased expression of DRD1 protein; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Cocaine results in increased expression of FOS protein]; Cocaine affects the reaction [SCH 23390 binds to DRD1 protein]; DRD1 protein affects the reaction [Cocaine results in increased expression of FOSB protein alternative form]; DRD1 protein affects the reaction [Cocaine results in increased expression of FOSB protein]
Cocaine promotes the reaction [DRD1 protein results in increased expression of FOS protein]; Cocaine promotes the reaction [DRD1 protein results in increased expression of NEO1 protein]; Cocaine promotes the reaction [DRD1 protein results in increased expression of PDYN protein]; Cocaine promotes the reaction [DRD1 protein results in increased expression of SYT7 protein]; Cocaine promotes the reaction [DRD1 protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Cocaine promotes the reaction [DRD1 protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]; DRD1 mutant form inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; DRD1 mutant form inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein]
DRD1 gene mutant form results in decreased susceptibility to Cocaine
DRD1 results in increased susceptibility to Cocaine
Cocaine affects the expression of DRD1 protein
DRD1 protein affects the susceptibility to Cocaine
Cocaine results in decreased expression of DRD1 protein
Cocaine deficiency results in increased expression of DRD1 mRNA		 CTD PMID:2213551 PMID:8001143 PMID:11421588 PMID:11602327 PMID:15049517 More... NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd2 dopamine receptor D2 decreases expression
multiple interactions
increases response to substance
decreases response to substance
affects expression
increases expression
increases activity
affects response to substance		 ISO
EXP		 Cocaine results in decreased expression of DRD2 mRNA; Cocaine results in decreased expression of DRD2 protein
Cocaine affects the reaction [Raclopride binds to DRD2]
DRD2 polymorphism results in increased susceptibility to Cocaine
DRD2 results in increased susceptibility to Cocaine
PDYN protein affects the reaction [Cocaine affects the expression of DRD2 protein]
DRD2 protein results in decreased susceptibility to Cocaine
Cocaine affects the expression of DRD2; Cocaine affects the expression of DRD2 mRNA; Cocaine affects the expression of DRD2 protein
Cocaine affects the reaction [Spiperone binds to DRD2 protein]; Cocaine promotes the reaction [[DRD2 protein results in increased phosphorylation of TH protein] which results in increased abundance of Dopamine]; Methadone affects the reaction [Cocaine affects the expression of DRD2 mRNA]; Spiperone inhibits the reaction [Cocaine promotes the reaction [[DRD2 protein results in increased phosphorylation of TH protein] which results in increased abundance of Dopamine]]
Cocaine results in increased expression of DRD2 mRNA; Cocaine results in increased expression of DRD2 protein
Cocaine results in increased activity of DRD2 protein
DRD2 protein affects the susceptibility to Cocaine
Cocaine deficiency results in increased expression of DRD2 mRNA; Cocaine results in increased expression of DRD2 protein		 CTD PMID:2213551 PMID:9892293 PMID:11126397 PMID:11602327 PMID:11790512 More... NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd3 dopamine receptor D3 decreases expression
affects response to substance
multiple interactions
increases expression
decreases response to substance
affects activity
affects expression
increases activity		 ISO
EXP		 Cocaine results in decreased expression of DRD3 protein
DRD3 affects the susceptibility to Cocaine
[3,4,4a,10b-tetrahydro-4-propyl-2H,5H-(1)benzopyrano(4,3-b)-1,4-oxazin-9-ol binds to and results in increased activity of DRD3 protein] which results in decreased susceptibility to Cocaine; [3,4,4a,10b-tetrahydro-4-propyl-2H,5H-(1)benzopyrano(4,3-b)-1,4-oxazin-9-ol co-treated with Cocaine] affects the localization of DRD3 protein; Cocaine promotes the reaction [DRD3 protein results in decreased expression of FOS protein]; Cocaine promotes the reaction [DRD3 protein results in decreased expression of NEO1 protein]; Cocaine promotes the reaction [DRD3 protein results in decreased expression of PDYN protein]; Cocaine promotes the reaction [DRD3 protein results in decreased expression of SYT7 protein]; Cocaine promotes the reaction [DRD3 protein results in decreased phosphorylation of and results in decreased activity of MAPK1 protein]; Cocaine promotes the reaction [DRD3 protein results in decreased phosphorylation of and results in decreased activity of MAPK3 protein]; DRD3 protein affects the reaction [Cocaine results in increased expression of NTS mRNA]; DRD3 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; DRD3 protein inhibits the reaction [Cocaine results in increased expression of PDYN protein]; SB 277011 inhibits the reaction [[3,4,4a,10b-tetrahydro-4-propyl-2H,5H-(1)benzopyrano(4,3-b)-1,4-oxazin-9-ol binds to and results in increased activity of DRD3 protein] which results in decreased susceptibility to Cocaine]
Cocaine results in increased expression of DRD3 mRNA
7-hydroxy-2-N,N-dipropylaminotetralin inhibits the reaction [Cocaine affects the activity of DRD3 protein]; Cocaine promotes the reaction [DRD3 protein binds to CAMK2A protein]; KN 93 inhibits the reaction [Cocaine promotes the reaction [DRD3 protein binds to CAMK2A protein]]
DRD3 protein results in decreased susceptibility to Cocaine
Cocaine affects the expression of DRD3 protein
Cocaine results in increased activity of DRD3 protein
DRD3 results in decreased susceptibility to Cocaine		 CTD PMID:10523822 PMID:10943692 PMID:11120399 PMID:12099907 PMID:15056714 More... NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G Drd4 dopamine receptor D4 increases response to substance
affects expression		 ISO
EXP		 DRD4 polymorphism results in increased susceptibility to Cocaine
Cocaine affects the expression of DRD4 mRNA		 CTD PMID:17671965 PMID:20187946 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Drd5 dopamine receptor D5 affects expression EXP Cocaine affects the expression of DRD5 mRNA CTD PMID:20187946 NCBI chr14:72,487,950...72,491,050
Ensembl chr14:72,489,347...72,490,774 		JBrowse link
G Drp2 dystrophin related protein 2 affects expression ISO Cocaine affects the expression of DRP2 protein CTD PMID:19393250 NCBI chr  X:97,607,577...97,658,117
Ensembl chr  X:97,607,719...97,655,684 		JBrowse link
G Dsp desmoplakin increases expression ISO Cocaine results in increased expression of DSP protein CTD PMID:17075605 NCBI chr17:26,623,602...26,671,692
Ensembl chr17:26,623,588...26,671,800 		JBrowse link
G Dusp1 dual specificity phosphatase 1 affects expression
increases phosphorylation		 EXP Cocaine affects the expression of DUSP1 mRNA
Cocaine results in increased phosphorylation of DUSP1 protein		 CTD PMID:18822274 PMID:20187946 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Dusp5 dual specificity phosphatase 5 affects expression
increases expression		 EXP Cocaine affects the expression of CPG21 mRNA
Cocaine results in increased expression of DUSP5 mRNA		 CTD PMID:20187946 PMID:27899881 NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818 		JBrowse link
G Dusp8 dual specificity phosphatase 8 multiple interactions
increases expression		 EXP 5,7-Dihydroxytryptamine inhibits the reaction [Cocaine results in increased expression of DUSP8 mRNA] CTD PMID:9813294 NCBI chr 1:197,167,392...197,184,285
Ensembl chr 1:197,169,422...197,182,921 		JBrowse link
G Dvl1 dishevelled segment polarity protein 1 affects expression EXP Cocaine affects the expression of DVL1 mRNA CTD PMID:20187946 NCBI chr 5:166,456,989...166,468,733
Ensembl chr 5:166,456,686...166,468,664 		JBrowse link
G Dync1i1 dynein cytoplasmic 1 intermediate chain 1 decreases expression ISO Cocaine results in decreased expression of DYNC1I1 mRNA CTD PMID:12629581 NCBI chr 4:33,852,597...34,166,159
Ensembl chr 4:33,852,927...34,166,149 		JBrowse link
G Dync1li2 dynein, cytoplasmic 1 light intermediate chain 2 increases expression EXP Cocaine results in increased expression of DYNC1LI2 protein CTD PMID:25100957 NCBI chr19:531,783...554,670
Ensembl chr19:531,812...554,670 		JBrowse link
G Dynll1 dynein light chain LC8-type 1 affects expression EXP Cocaine affects the expression of DYNLL1 mRNA CTD PMID:20187946 NCBI chr12:41,312,365...41,316,157
Ensembl chr12:41,312,367...41,314,741 		JBrowse link
G Eci2 enoyl-CoA delta isomerase 2 affects expression EXP Cocaine affects the expression of ECI2 mRNA CTD PMID:20187946 NCBI chr17:29,850,884...29,886,781
Ensembl chr17:29,870,391...29,886,781 		JBrowse link
G Edn1 endothelin 1 increases expression EXP
ISO		 Cocaine results in increased expression of EDN1 protein CTD PMID:9714087 PMID:11948058 PMID:17420087 PMID:18813882 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Ednra endothelin receptor type A increases expression ISO
EXP		 Cocaine results in increased expression of EDNRA protein CTD PMID:17420087 PMID:18813882 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Ednrb endothelin receptor type B affects expression EXP Cocaine affects the expression of EDNRB mRNA CTD PMID:20187946 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 affects expression EXP Cocaine affects the expression of EEF1A1 mRNA CTD PMID:20187946 NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839 		JBrowse link
G Eef1a2 eukaryotic translation elongation factor 1 alpha 2 affects expression EXP Cocaine affects the expression of EEF1A2 mRNA CTD PMID:20187946 NCBI chr 3:168,265,893...168,275,071
Ensembl chr 3:168,195,357...168,275,071 		JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma decreases expression ISO Cocaine results in decreased expression of EEF1G mRNA CTD PMID:15009677 NCBI chr 1:205,860,713...205,871,319
Ensembl chr 1:205,860,698...205,872,382 		JBrowse link
G Efcab3 EF-hand calcium binding domain 3 affects expression
decreases expression		 EXP Cocaine affects the expression of EFCAB3 mRNA
Cocaine results in decreased expression of EFCAB3 mRNA		 CTD PMID:17898221 PMID:20187946 NCBI chr10:89,583,526...90,077,260
Ensembl chr10:89,644,522...90,077,259 		JBrowse link
G Efna1 ephrin A1 affects expression EXP Cocaine affects the expression of EFNA1 mRNA CTD PMID:15691709 NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866 		JBrowse link
G Efna2 ephrin A2 affects expression EXP Cocaine affects the expression of EFNA2 mRNA CTD PMID:15691709 NCBI chr 7:9,515,635...9,528,071
Ensembl chr 7:9,516,429...9,527,061 		JBrowse link
G Efna3 ephrin A3 affects expression EXP Cocaine affects the expression of EFNA3 mRNA CTD PMID:15691709 NCBI chr 2:174,729,192...174,738,111
Ensembl chr 2:174,729,764...174,738,736 		JBrowse link
G Efna4 ephrin A4 affects expression EXP Cocaine affects the expression of EFNA4 mRNA CTD PMID:15691709 NCBI chr 2:174,748,729...174,752,979
Ensembl chr 2:174,748,724...174,752,979 		JBrowse link
G Efna5 ephrin A5 increases expression EXP Cocaine results in increased expression of EFNA5 mRNA CTD PMID:15691709 NCBI chr 9:102,316,753...102,595,480
Ensembl chr 9:102,320,295...102,597,413 		JBrowse link
G Efnb1 ephrin B1 increases expression EXP Cocaine results in increased expression of EFNB1 mRNA CTD PMID:15691709 PMID:17898221 NCBI chr  X:64,257,351...64,270,158
Ensembl chr  X:64,257,351...64,270,157 		JBrowse link
G Efnb2 ephrin B2 increases expression EXP Cocaine results in increased expression of EFNB2 mRNA CTD PMID:15691709 NCBI chr16:80,783,389...80,827,420
Ensembl chr16:80,783,417...80,824,391 		JBrowse link
G Efnb3 ephrin B3 increases expression EXP Cocaine results in increased expression of EFNB3 mRNA CTD PMID:15691709 NCBI chr10:54,274,506...54,281,951
Ensembl chr10:54,274,506...54,280,471 		JBrowse link
G Eftud2 elongation factor Tu GTP binding domain containing 2 affects expression EXP Cocaine affects the expression of EFTUD2 mRNA CTD PMID:20187946 NCBI chr10:87,804,893...87,852,181
Ensembl chr10:87,804,892...87,846,079 		JBrowse link
G Egfr epidermal growth factor receptor decreases expression ISO Cocaine results in decreased expression of EGFR mRNA CTD PMID:18000554 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Egr1 early growth response 1 affects expression
multiple interactions
increases response to substance
increases expression
decreases expression		 ISO
EXP		 Cocaine affects the expression of EGR1 mRNA
[Cocaine co-treated with Caffeine] results in increased expression of EGR1 mRNA; Cocaine promotes the reaction [Caffeine results in increased expression of EGR1 mRNA]
EGR1 results in increased susceptibility to Cocaine
Cocaine results in increased expression of EGR1 mRNA; Cocaine results in increased expression of EGR1 protein
NPPC protein inhibits the reaction [Cocaine results in increased expression of EGR1 mRNA]
Cocaine deficiency results in decreased expression of EGR1 mRNA		 CTD PMID:1347779 PMID:7905595 PMID:9890435 PMID:10971643 PMID:11860464 More... NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Egr2 early growth response 2 increases expression
affects expression		 ISO
EXP		 Cocaine results in increased expression of EGR2 mRNA
Cocaine affects the expression of EGR2 mRNA		 CTD PMID:20056891 PMID:20187946 PMID:27899881 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562 		JBrowse link
G Egr3 early growth response 3 affects expression
increases expression
multiple interactions
decreases expression		 EXP
ISO		 Cocaine affects the expression of EGR3 mRNA
Cocaine results in increased expression of EGR3 mRNA
[Cocaine co-treated with Cocaine deficiency] promotes the reaction [RUNX2 protein binds to EGR3 promoter]
Cocaine deficiency results in decreased expression of EGR3 mRNA		 CTD PMID:16459018 PMID:20187946 PMID:27126842 PMID:30158054 NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627 		JBrowse link
G Egr4 early growth response 4 increases expression EXP Cocaine results in increased expression of EGR4 mRNA CTD PMID:27899881 NCBI chr 4:118,047,869...118,050,328
Ensembl chr 4:118,047,869...118,050,328 		JBrowse link
G Ehd2 EH-domain containing 2 decreases expression EXP Cocaine results in decreased expression of EHD2 mRNA CTD PMID:17898221 NCBI chr 1:76,639,568...76,658,747
Ensembl chr 1:76,637,482...76,658,783 		JBrowse link
G Ehmt1 euchromatic histone lysine methyltransferase 1 decreases expression ISO Cocaine results in decreased expression of EHMT1 mRNA CTD PMID:20056891 NCBI chr 3:7,580,680...7,729,046
Ensembl chr 3:7,580,683...7,729,007 		JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 multiple interactions
decreases expression
decreases response to substance		 ISO Cocaine inhibits the reaction [Cocaine promotes the reaction [EHMT2 protein binds to FOSB protein]]; Cocaine promotes the reaction [EHMT2 protein binds to FOSB protein]; EHMT2 inhibits the reaction [Cocaine results in increased expression of ATM mRNA]; EHMT2 inhibits the reaction [Cocaine results in increased expression of ELMO1 mRNA]; EHMT2 inhibits the reaction [Cocaine results in increased expression of TGFBR1 mRNA]; EHMT2 inhibits the reaction [Cocaine results in increased expression of TNFRSF25 mRNA]; EHMT2 inhibits the reaction [Cocaine results in increased expression of USP9X mRNA]; EHMT2 inhibits the reaction [Cocaine results in increased expression of WNK3 mRNA]; EHMT2 protein inhibits the reaction [Cocaine results in increased expression of FOSB mRNA]
Cocaine results in decreased expression of EHMT2 mRNA; Cocaine results in decreased expression of EHMT2 protein
EHMT2 results in decreased susceptibility to Cocaine		 CTD PMID:20056891 NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547 		JBrowse link
G Eif1a eukaryotic translation initiation factor 1A increases expression EXP Cocaine results in increased expression of EIF1A mRNA; Cocaine results in increased expression of EIF1AY mRNA CTD PMID:17898221 NCBI chr18:39,325,695...39,338,043
Ensembl chr18:39,325,202...39,338,696 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases expression
multiple interactions		 EXP Cocaine results in increased expression of EIF2AK3 protein
6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Cocaine results in increased expression of EIF2AK3 protein]; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of EIF2AK3 protein]; N-phenyl-7-(hydroxyimino)cyclopropa(b)chromen-1a-carboxamide inhibits the reaction [Cocaine results in increased expression of EIF2AK3 protein]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of EIF2AK3 protein]		 CTD PMID:17303341 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation EXP Cocaine results in increased phosphorylation of EIF2S1 CTD PMID:18593214 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
G Eif3a eukaryotic translation initiation factor 3, subunit A increases expression EXP Cocaine results in increased expression of EIF3A mRNA CTD PMID:17898221 NCBI chr 1:259,902,767...259,932,976
Ensembl chr 1:259,902,680...259,932,976 		JBrowse link
G Eif3b eukaryotic translation initiation factor 3, subunit B affects expression EXP Cocaine affects the expression of EIF3B mRNA CTD PMID:20187946 NCBI chr12:14,196,403...14,220,865
Ensembl chr12:14,196,403...14,220,886 		JBrowse link
G Eif3c eukaryotic translation initiation factor 3, subunit C increases expression EXP Cocaine results in increased expression of EIF3C mRNA CTD PMID:17898221 NCBI chr 1:181,134,604...181,152,489
Ensembl chr 1:181,134,604...181,152,493 		JBrowse link
G Eif3e eukaryotic translation initiation factor 3 subunit E affects expression EXP Cocaine affects the expression of EIF3E mRNA CTD PMID:20187946 NCBI chr 7:74,339,848...74,372,483
Ensembl chr 7:74,339,828...74,373,096 		JBrowse link
G Eif4b eukaryotic translation initiation factor 4B multiple interactions
increases expression		 ISO FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of EIF4B mRNA] CTD PMID:18355967 NCBI chr 7:133,206,637...133,228,436 JBrowse link
G Eif5a eukaryotic translation initiation factor 5A decreases expression
increases expression
affects expression		 ISO
EXP		 Cocaine results in decreased expression of EIF5A mRNA
Cocaine results in increased expression of EIF5A mRNA
Cocaine affects the expression of EIF5A mRNA		 CTD PMID:15009677 PMID:16710320 PMID:20187946 NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656 		JBrowse link
G Eif5b eukaryotic translation initiation factor 5B increases expression EXP Cocaine results in increased expression of EIF5B mRNA CTD PMID:17898221 NCBI chr 9:40,222,769...40,277,482
Ensembl chr 9:40,222,898...40,277,482 		JBrowse link
G Eif5b-ps1 eukaryotic translation initiation factor 5B, pseudogene 1 increases expression EXP Cocaine results in increased expression of EIF5B-PS1 mRNA CTD PMID:17898221 NCBI chr19:35,387,899...35,392,006 JBrowse link
G Elane elastase, neutrophil expressed multiple interactions ISO [Cocaine affects the reaction [Antibodies, Antineutrophil Cytoplasmic binds to ELANE protein]] which results in decreased activity of ELANE protein; Cocaine affects the reaction [Antibodies, Antineutrophil Cytoplasmic binds to ELANE protein] CTD PMID:18438818 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100 		JBrowse link
G Elmo1 engulfment and cell motility 1 multiple interactions
increases expression		 ISO EHMT2 inhibits the reaction [Cocaine results in increased expression of ELMO1 mRNA] CTD PMID:20056891 NCBI chr17:44,286,495...44,822,668
Ensembl chr17:44,286,485...44,822,788 		JBrowse link
G Emc9 ER membrane protein complex subunit 9 affects expression EXP Cocaine affects the expression of EMC9 mRNA CTD PMID:20187946 NCBI chr15:29,071,881...29,076,098
Ensembl chr15:29,071,883...29,076,098 		JBrowse link
G Enah ENAH, actin regulator increases expression EXP Cocaine results in increased expression of ENAH mRNA CTD PMID:17898221 NCBI chr13:93,617,747...93,738,119
Ensembl chr13:93,626,944...93,740,955 		JBrowse link
G Enc1 ectodermal-neural cortex 1 increases expression EXP Cocaine results in increased expression of ENC1 mRNA CTD PMID:17898221 NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713 		JBrowse link
G Enho energy homeostasis associated decreases expression ISO Cocaine results in decreased expression of ENHO mRNA CTD PMID:16710320 NCBI chr 5:56,800,980...56,802,777
Ensembl chr 5:56,800,980...56,802,777 		JBrowse link
G Eno2 enolase 2 decreases expression
increases expression		 ISO Cocaine results in decreased expression of ENO2 mRNA
Cocaine results in increased expression of ENO2 protein		 CTD PMID:12629581 PMID:17075605 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980 		JBrowse link
G Enpp5 ectonucleotide pyrophosphatase/phosphodiesterase family member 5 increases expression ISO Cocaine results in increased expression of ENPP5 mRNA CTD PMID:15009677 NCBI chr 9:16,910,187...16,917,633
Ensembl chr 9:16,910,831...16,917,480 		JBrowse link
G Entpd2 ectonucleoside triphosphate diphosphohydrolase 2 decreases expression EXP Cocaine results in decreased expression of ENTPD2 protein CTD PMID:25100957 NCBI chr 3:8,213,575...8,219,094
Ensembl chr 3:8,213,663...8,226,866 		JBrowse link
G Entpd3 ectonucleoside triphosphate diphosphohydrolase 3 multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in decreased expression of ENTPD3 mRNA CTD PMID:18355967 NCBI chr 8:120,246,412...120,277,943
Ensembl chr 8:120,247,121...120,277,943 		JBrowse link
G Epha1 Eph receptor A1 affects expression EXP Cocaine affects the expression of EPHA1 mRNA CTD PMID:15691709 NCBI chr 4:71,246,409...71,260,920
Ensembl chr 4:71,246,409...71,260,846 		JBrowse link
G Epha2 Eph receptor A2 affects expression EXP Cocaine affects the expression of EPHA2 mRNA CTD PMID:15691709 NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117 		JBrowse link
G Epha3 Eph receptor A3 affects expression EXP Cocaine affects the expression of EPHA3 mRNA CTD PMID:15691709 NCBI chr11:1,138,485...1,474,102
Ensembl chr11:1,140,985...1,473,900 		JBrowse link
G Epha4 Eph receptor A4 affects expression
increases expression		 EXP Cocaine affects the expression of EPHA4 mRNA
Cocaine results in increased expression of EPHA4 mRNA		 CTD PMID:15691709 PMID:17898221 NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139 		JBrowse link
G Epha5 EPH receptor A5 affects expression EXP Cocaine affects the expression of EPHA5 mRNA CTD PMID:15691709 NCBI chr14:23,653,393...24,020,129
Ensembl chr14:23,653,393...24,017,317 		JBrowse link
G Epha7 Eph receptor A7 affects expression EXP Cocaine affects the expression of EPHA7 mRNA CTD PMID:15691709 NCBI chr 5:42,975,353...43,128,703
Ensembl chr 5:42,975,405...43,127,112 		JBrowse link
G Epha8 Eph receptor A8 affects expression EXP Cocaine affects the expression of EPHA8 mRNA CTD PMID:15691709 NCBI chr 5:149,166,107...149,193,515
Ensembl chr 5:149,166,697...149,193,399 		JBrowse link
G Ephb1 Eph receptor B1 increases expression ISO
EXP		 Cocaine results in increased expression of EPHB1 protein
Cocaine results in increased expression of EPHB1 mRNA		 CTD PMID:11146119 PMID:15691709 NCBI chr 8:102,507,549...102,944,839
Ensembl chr 8:102,507,549...102,944,839 		JBrowse link
G Ephb2 Eph receptor B2 increases expression EXP Cocaine results in increased expression of EPHB2 mRNA CTD PMID:15691709 NCBI chr 5:148,889,574...149,077,027
Ensembl chr 5:148,897,246...149,077,059 		JBrowse link
G Ephb3 Eph receptor B3 affects expression EXP Cocaine affects the expression of EPHB3 mRNA CTD PMID:15691709 NCBI chr11:79,840,668...79,859,345
Ensembl chr11:79,840,668...79,859,370 		JBrowse link
G Ephb4 EPH receptor B4 decreases expression
affects expression		 ISO
EXP		 Cocaine results in decreased expression of EPHB4 mRNA
Cocaine affects the expression of EPHB4 mRNA		 CTD PMID:15691709 PMID:18000554 NCBI chr12:19,326,411...19,351,667
Ensembl chr12:19,326,427...19,351,314 		JBrowse link
G Ephb6 Eph receptor B6 affects expression EXP Cocaine affects the expression of EPHB6 mRNA CTD PMID:15691709 NCBI chr 4:70,491,973...70,507,230
Ensembl chr 4:70,491,973...70,507,230 		JBrowse link
G Erbin erbb2 interacting protein multiple interactions ISO HDAC5 affects the reaction [Cocaine affects the expression of ERBIN mRNA] CTD PMID:17988634 NCBI chr 2:34,926,962...35,028,440
Ensembl chr 2:34,928,863...35,027,852 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions
increases expression		 EXP 6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Cocaine results in increased expression of ERN1 protein]; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of ERN1 protein]; N-phenyl-7-(hydroxyimino)cyclopropa(b)chromen-1a-carboxamide inhibits the reaction [Cocaine results in increased expression of ERN1 protein]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of ERN1 protein] CTD PMID:17303341 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G Ess2 ess-2 splicing factor homolog decreases expression EXP Cocaine results in decreased expression of ESS2 mRNA CTD PMID:17898221 NCBI chr11:83,075,893...83,085,849
Ensembl chr11:83,075,925...83,084,846 		JBrowse link
G Etf1 eukaryotic translation termination factor 1 affects expression EXP Cocaine affects the expression of ETF1 mRNA CTD PMID:20187946 NCBI chr18:26,502,413...26,530,753
Ensembl chr18:26,504,080...26,530,810 		JBrowse link
G Etfa electron transfer flavoprotein subunit alpha affects expression EXP Cocaine affects the expression of ETFA mRNA CTD PMID:20187946 NCBI chr 8:55,835,115...55,891,890
Ensembl chr 8:55,835,134...55,891,969 		JBrowse link
G Exoc2 exocyst complex component 2 increases expression EXP Cocaine results in increased expression of EXOC2 protein CTD PMID:25100957 NCBI chr17:33,506,289...33,698,246
Ensembl chr17:33,506,338...33,693,289 		JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 increases expression ISO Cocaine results in increased expression of EYA1 mRNA CTD PMID:15009677 NCBI chr 5:4,863,501...5,101,483
Ensembl chr 5:4,955,543...5,101,483 		JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 affects expression EXP Cocaine affects the expression of EYA2 mRNA CTD PMID:20187946 NCBI chr 3:154,335,598...154,519,006
Ensembl chr 3:154,335,400...154,518,793 		JBrowse link
G Ezr ezrin decreases expression ISO Cocaine results in decreased expression of EZR mRNA CTD PMID:20948987 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505 		JBrowse link
G Fadd Fas associated via death domain affects expression
decreases expression
multiple interactions		 EXP Cocaine affects the expression of FADD mRNA
Cocaine results in decreased expression of FADD protein modified form
Raclopride affects the reaction [Cocaine affects the expression of FADD protein]		 CTD PMID:18580876 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Fahd1 fumarylacetoacetate hydrolase domain containing 1 increases expression EXP Cocaine results in increased expression of FAHD1 protein CTD PMID:25100957 NCBI chr10:13,873,539...13,874,978
Ensembl chr10:13,873,527...13,875,012 		JBrowse link
G Faim Fas apoptotic inhibitory molecule affects expression ISO Cocaine affects the expression of FAIM mRNA CTD PMID:15681117 NCBI chr 8:99,543,877...99,569,499
Ensembl chr 8:99,542,405...99,560,562 		JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 increases expression EXP Cocaine results in increased expression of FAIM2 mRNA CTD PMID:16076954 NCBI chr 7:130,632,368...130,659,353
Ensembl chr 7:130,633,348...130,659,168 		JBrowse link
G Fam184b family with sequence similarity 184, member B decreases expression EXP Cocaine results in decreased expression of FAM184B mRNA CTD PMID:27899881 NCBI chr14:65,475,489...65,591,388
Ensembl chr14:65,475,489...65,591,388 		JBrowse link
G Fam20c FAM20C, golgi associated secretory pathway kinase affects expression EXP Cocaine affects the expression of FAM20C mRNA CTD PMID:20187946 NCBI chr12:15,826,864...15,885,423
Ensembl chr12:15,826,871...15,884,543 		JBrowse link
G Fam78b family with sequence similarity 78, member B decreases expression EXP Cocaine results in decreased expression of FAM78B mRNA CTD PMID:17898221 NCBI chr13:79,162,393...79,250,958
Ensembl chr13:79,162,228...79,250,500 		JBrowse link
G Fas Fas cell surface death receptor increases expression ISO Cocaine results in increased expression of FAS mRNA CTD PMID:16710320 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fbxl3 F-box and leucine-rich repeat protein 3 increases expression EXP Cocaine results in increased expression of FBXL3 mRNA CTD PMID:17898221 NCBI chr15:79,906,795...79,926,678
Ensembl chr15:79,906,795...79,927,867 		JBrowse link
G Fbxo46 F-box protein 46 affects expression EXP Cocaine affects the expression of FBXO46 mRNA CTD PMID:20187946 NCBI chr 1:78,770,059...78,786,582
Ensembl chr 1:78,770,018...78,790,097 		JBrowse link
G Fcgr2b Fc gamma receptor 2B decreases expression EXP Cocaine results in decreased expression of FCGR2B mRNA CTD PMID:27899881 NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 increases expression ISO Cocaine results in increased expression of FDFT1 mRNA CTD PMID:17205118 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287 		JBrowse link
G Fev FEV transcription factor, ETS family member decreases expression EXP Cocaine results in decreased expression of FEV mRNA CTD PMID:17898221 NCBI chr 9:76,439,164...76,443,603
Ensembl chr 9:76,439,172...76,443,065 		JBrowse link
G Fgd5 FYVE, RhoGEF and PH domain containing 5 increases expression EXP Cocaine results in increased expression of FGD5 mRNA CTD PMID:17898221 NCBI chr 4:124,497,061...124,594,564
Ensembl chr 4:124,497,068...124,594,563 		JBrowse link
G Fgf12 fibroblast growth factor 12 affects expression EXP Cocaine affects the expression of FGF12 mRNA CTD PMID:20187946 NCBI chr11:71,997,151...72,564,757
Ensembl chr11:71,997,099...72,562,607 		JBrowse link
G Fgf2 fibroblast growth factor 2 decreases expression ISO Cocaine results in decreased expression of FGF2 mRNA CTD PMID:12629581 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 increases expression EXP Cocaine results in increased expression of FGFR1 mRNA CTD PMID:16076954 NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
G Fh fumarate hydratase affects expression ISO Cocaine affects the expression of FH1 protein CTD PMID:19393250 NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266 		JBrowse link
G Fis1 fission, mitochondrial 1 increases expression ISO Cocaine results in increased expression of FIS1 mRNA CTD PMID:31494168 NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377 		JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B affects expression EXP Cocaine affects the expression of FKBP1B mRNA CTD PMID:20187946 NCBI chr 6:27,832,128...27,850,600
Ensembl chr 6:27,838,802...27,848,653 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 increases expression EXP cocaine increases expression of Fkbp5 mRNA in bed nucleus of the stria terminalis, central amygdala and paraventricular nucleus RGD PMID:31029877 RGD:401976486 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674 		JBrowse link
G Fkbpl FKBP prolyl isomerase like affects expression EXP Cocaine affects the expression of FKBPL mRNA CTD PMID:20187946 NCBI chr20:4,099,845...4,101,315
Ensembl chr20:4,099,806...4,101,368 		JBrowse link
G Flrt3 fibronectin leucine rich transmembrane protein 3 increases expression ISO Cocaine results in increased expression of FLRT3 mRNA CTD PMID:18000554 NCBI chr 3:127,994,491...128,008,137
Ensembl chr 3:127,994,226...128,007,841 		JBrowse link
G Flywch1 FLYWCH-type zinc finger 1 decreases expression EXP Cocaine results in decreased expression of FLYWCH1 mRNA CTD PMID:17898221 NCBI chr10:12,774,644...12,794,373
Ensembl chr10:12,774,653...12,794,267 		JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 decreases expression EXP Cocaine results in decreased expression of FMR1 mRNA CTD PMID:24810662 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050 		JBrowse link
G Fndc1 fibronectin type III domain containing 1 multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in decreased expression of FNDC1 mRNA CTD PMID:18355967 NCBI chr 1:47,281,839...47,364,247
Ensembl chr 1:47,281,844...47,364,259 		JBrowse link
G Fndc5 fibronectin type III domain containing 5 affects expression EXP Cocaine affects the expression of FNDC5 mRNA CTD PMID:20187946 NCBI chr 5:141,481,593...141,491,257
Ensembl chr 5:141,481,590...141,490,731 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
affects expression
decreases expression
increases activity
decreases response to substance
increases phosphorylation
increases expression		 ISO
EXP		 [Cocaine co-treated with SLC6A3 protein] results in increased expression of FOS protein; Cocaine inhibits the reaction [[Dopamine co-treated with SLC6A3 protein] results in increased expression of FOS mRNA]; Cocaine inhibits the reaction [[Dopamine co-treated with SLC6A3 protein] results in increased expression of FOS protein]
[[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOS protein] which affects the expression of NEO1 protein; [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOS protein] which affects the expression of PDYN protein; [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOS protein] which affects the expression of SYT7 protein; [Cocaine co-treated with Caffeine] results in increased expression of FOS mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of ATPAF1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of CD4 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of CORO7 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of ENTPD3 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of FNDC1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of ITPR1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of NEXN mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PBX2 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PER1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PINX1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PKNOX2 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PLPP1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PRKCZ mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of SHANK3 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of SYT9 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of THRA mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of ADGRA1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of CAB39L mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of CAMK1G mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of CBLN1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of GRIP1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of INA mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of LARGE1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of NRIP3 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of SATB2 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of SORCS3 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of TENM4 mRNA; [Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOS protein; [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOS protein; Baclofen inhibits the reaction [Cocaine results in increased expression of FOS protein]; CDK5R1 protein inhibits the reaction [Cocaine affects the expression of FOS mRNA]; CDK5R1 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; CNR1 mutant form inhibits the reaction [Cocaine results in increased expression of FOS protein]; Cocaine promotes the reaction [Caffeine results in increased expression of FOS mRNA]; Cocaine promotes the reaction [DRD1 protein results in increased expression of FOS protein]; Cocaine promotes the reaction [DRD3 protein results in decreased expression of FOS protein]; cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester inhibits the reaction [Cocaine results in increased expression of FOS protein]; DRD3 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of BDNF mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of CALR mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of DLK2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of HOMER2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of HS3ST2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of MAPK11 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of NCALD mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of NPTXR mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of NRN1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of PRKCA mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of SATB1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of SEZ6L mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of ATP1B3 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of ATP8B2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of CLK1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of CTSB mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of EIF4B mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of GPC5 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of KCNT1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of KDM3A mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of LIN7B mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of LZTS3 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of MEPCE mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of NIT2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of NOS3 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of PBX3 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of PPP1R7 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of PRPF18 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of PTPRV mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of SBSN mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of SYNE1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of SYT2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of TSPOAP1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of ZFPM1 mRNA]; GPX1 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine inhibits the reaction [Cocaine results in increased expression of FOS protein]; N-methyl-3-(bis(4'-fluorophenyl)methoxy)tropane inhibits the reaction [Cocaine results in increased expression of FOS protein]; NTRK2 protein affects the reaction [Cocaine affects the expression of FOS protein]; prolinedithiocarbamate inhibits the reaction [Cocaine results in increased expression of FOS protein]; RPS6KA3 affects the reaction [Cocaine results in increased phosphorylation of FOS protein]; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOS protein]; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOS protein]; SL 327 inhibits the reaction [Cocaine results in increased activity of FOS protein]; SL 327 inhibits the reaction [Cocaine results in increased expression of FOS mRNA]; SL 327 inhibits the reaction [Cocaine results in increased expression of FOS protein]
Cocaine affects the expression of FOS mRNA; Cocaine affects the expression of FOS protein
Cocaine deficiency results in decreased expression of FOS protein; Cocaine results in decreased expression of FOS protein
FOS protein mutant form results in decreased susceptibility to Cocaine
[Morphine co-treated with Cocaine] affects the expression of FOS; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Cocaine results in increased expression of FOS protein]; Alcohols promotes the reaction [Cocaine results in increased expression of FOS protein]; Baclofen inhibits the reaction [Cocaine results in increased expression of FOS protein]; Chloral Hydrate inhibits the reaction [Cocaine results in increased expression of FOS protein]; Cocaine promotes the reaction [[SK&F 81297 co-treated with Quinpirole] results in increased expression of FOS protein]; Cocaine promotes the reaction [Cocaine results in increased expression of FOS mRNA]; Cocaine promotes the reaction [Ethanol results in increased expression of FOS protein]; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of FOS protein]; ecopipam inhibits the reaction [Cocaine results in increased expression of FOS protein]; Ethanol promotes the reaction [Cocaine results in increased expression of FOS protein]; Muscimol inhibits the reaction [Cocaine results in increased expression of FOS protein]; NPPC protein inhibits the reaction [Cocaine results in increased expression of FOS mRNA]; Reserpine inhibits the reaction [Cocaine results in increased expression of FOS protein]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of FOS protein]; Urethane inhibits the reaction [Cocaine results in increased expression of FOS protein]; volinanserin inhibits the reaction [Cocaine results in increased expression of FOS protein]
Cocaine results in increased expression of FOS mRNA; Cocaine results in increased expression of FOS protein		 CTD PMID:1498673 PMID:2118661 PMID:7905595 PMID:10415707 PMID:10521585 More... NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
affects expression
increases expression 		ISO
EXP		 Cocaine results in increased expression of FOSB protein
[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOSB protein; [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOSB protein; [JUND protein results in decreased activity of FOSB protein] which results in decreased susceptibility to Cocaine; Cocaine inhibits the reaction [Cocaine promotes the reaction [EHMT2 protein binds to FOSB protein]]; Cocaine promotes the reaction [EHMT2 protein binds to FOSB protein]; EHMT2 protein inhibits the reaction [Cocaine results in increased expression of FOSB mRNA]; N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine inhibits the reaction [Cocaine results in increased expression of FOSB protein alternative form]; PPP1R1B gene mutant form inhibits the reaction [Cocaine results in increased expression of FOSB protein]; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOSB protein]; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOSB protein]; SL 327 inhibits the reaction [Cocaine results in increased expression of FOSB protein alternative form]
Cocaine affects the expression of FOSB mRNA
Cocaine results in increased expression of FOSB mRNA; Cocaine results in increased expression of FOSB protein; Cocaine results in increased expression of FOSB protein alternative form
Cocaine affects the expression of FOSB mRNA; Cocaine affects the expression of FOSB protein
DRD1 protein affects the reaction [Cocaine results in increased expression of FOSB protein alternative form]; DRD1 protein affects the reaction [Cocaine results in increased expression of FOSB protein]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of FOSB protein alternative form]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of FOSB protein]
cocaine increases expression of Fosb protein in Nucleus Accumbens and Caudate Putamen
cocaine increases expression of Fosb protein in Brain
Cocaine increases expression of Fosb protein in brain
Cocaine increases expression of Fosb protein in caudate���putamen
Cocaine increases expression of Fosb protein in Nucleus Accumbens and Caudate putamen
Cocaine increases expression of Fosb mRNA and protein in Nucleus Accumbens and Caudate Putamen
cocaine increases expression of Fosb protein in dorsal striatum and nucelus accumbens		 CTD
RGD		 PMID:10103106 PMID:11391778 PMID:11739600 PMID:12417638 PMID:15056714 More... RGD:401851063, RGD:401851078, RGD:401851084, RGD:401900302, RGD:401900166, RGD:401900126, RGD:401901287 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit affects expression
decreases expression		 EXP
ISO		 Cocaine affects the expression of FOSL1 mRNA
Cocaine results in decreased expression of FOSL1 mRNA		 CTD PMID:12117546 PMID:12629581 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930 		JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit multiple interactions
decreases expression		 ISO Cocaine promotes the reaction [JUN protein binds to FOSL2 protein]
Cocaine results in decreased expression of FOSL2 protein
[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOSL2 protein; [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOSL2 protein; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOSL2 protein]; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOSL2 protein]		 CTD PMID:15056714 PMID:15814102 NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034 		JBrowse link
G Foxc2 forkhead box C2 decreases expression EXP Cocaine results in decreased expression of FOXC2 mRNA CTD PMID:17898221 NCBI chr19:49,186,034...49,188,736
Ensembl chr19:49,185,662...49,188,737 		JBrowse link
G Foxo1 forkhead box O1 decreases expression EXP Cocaine results in decreased expression of FOXO1 mRNA CTD PMID:17898221 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G Foxp1 forkhead box P1 increases expression ISO Cocaine deficiency results in increased expression of FOXP1 mRNA CTD PMID:27126842 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G Fras1 Fraser extracellular matrix complex subunit 1 increases expression EXP Cocaine results in increased expression of FRAS1 mRNA CTD PMID:17898221 NCBI chr14:12,791,407...13,200,862
Ensembl chr14:12,793,599...13,200,726 		JBrowse link
G Frem2 FRAS1 related extracellular matrix 2 decreases expression EXP Cocaine results in decreased expression of FREM2 mRNA CTD PMID:27899881 NCBI chr 2:137,602,784...137,740,785
Ensembl chr 2:137,602,784...137,740,785 		JBrowse link
G Frmd5 FERM domain containing 5 decreases expression EXP Cocaine results in decreased expression of FRMD5 mRNA CTD PMID:17898221 NCBI chr 3:108,492,099...108,763,715
Ensembl chr 3:108,474,562...108,763,498 		JBrowse link
G Frs3 fibroblast growth factor receptor substrate 3 affects expression EXP Cocaine affects the expression of FRS3 mRNA CTD PMID:20187946 NCBI chr 9:13,288,559...13,297,285
Ensembl chr 9:13,288,667...13,295,382 		JBrowse link
G Fubp1 far upstream element binding protein 1 affects expression EXP Cocaine affects the expression of FUBP1 mRNA CTD PMID:20187946 NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602 		JBrowse link
G Fut8 fucosyltransferase 8 affects expression EXP Cocaine affects the expression of FUT8 mRNA CTD PMID:20187946 NCBI chr 6:95,949,246...96,176,677
Ensembl chr 6:95,949,991...96,176,677 		JBrowse link
G Fzd6 frizzled class receptor 6 affects expression EXP Cocaine affects the expression of FZD6 mRNA CTD PMID:20187946 NCBI chr 7:70,055,012...70,086,781
Ensembl chr 7:70,055,068...70,086,776 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases expression EXP Cocaine results in increased expression of G6PD protein CTD PMID:25100957 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 affects expression
decreases expression
increases expression		 EXP Cocaine affects the expression of GABBR1 mRNA
Cocaine results in decreased expression of GABBR1 mRNA
Cocaine results in increased expression of GABBR1 mRNA		 CTD PMID:11793422 PMID:16076954 PMID:20187946 NCBI chr20:1,464,534...1,494,114
Ensembl chr20:1,464,534...1,493,994 		JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 decreases phosphorylation EXP Cocaine results in decreased phosphorylation of GABBR2 protein CTD PMID:12716959 NCBI chr 5:60,947,517...61,288,104
Ensembl chr 5:60,947,526...61,288,104 		JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 affects expression
multiple interactions		 EXP
ISO		 Cocaine affects the expression of GABRA1 protein
1-(3-chlorophenyl)piperazine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 3,4-Methylenedioxyamphetamine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [1-(3-chlorophenyl)piperazine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [3,4-Methylenedioxyamphetamine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]
Cocaine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]		 CTD PMID:20826313 PMID:23266428 PMID:32209479 NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864 		JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 increases expression EXP Cocaine results in increased expression of GABRB1 mRNA CTD PMID:17898221 NCBI chr14:36,068,725...36,548,946
Ensembl chr14:36,080,393...36,548,948 		JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 multiple interactions ISO
EXP		 1-(3-chlorophenyl)piperazine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 3,4-Methylenedioxyamphetamine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [1-(3-chlorophenyl)piperazine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [3,4-Methylenedioxyamphetamine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]
Cocaine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]		 CTD PMID:23266428 PMID:32209479 NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251 		JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 affects expression
multiple interactions		 EXP Cocaine affects the expression of GABRB3 mRNA
Cocaine affects the phosphorylation of and affects the expression of GABRB3 protein		 CTD PMID:20187946 PMID:20826313 NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961 		JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 multiple interactions
increases expression		 ISO
EXP		 1-(3-chlorophenyl)piperazine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 3,4-Methylenedioxyamphetamine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [1-(3-chlorophenyl)piperazine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [3,4-Methylenedioxyamphetamine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]
Cocaine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
Cocaine deficiency results in increased expression of GABRG2 mRNA		 CTD PMID:23266428 PMID:27126842 PMID:32209479 NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346 		JBrowse link
G Gad1 glutamate decarboxylase 1 decreases expression
increases expression		 ISO
EXP		 Cocaine results in decreased expression of GAD1 mRNA
Cocaine results in increased expression of GAD1 protein		 CTD PMID:12629581 PMID:15295023 PMID:18611417 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gal galanin and GMAP prepropeptide multiple interactions ISO GAL protein inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; GAL protein inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:19099295 NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959 		JBrowse link
G Galk1 galactokinase 1 affects expression EXP Cocaine affects the expression of GALK1 mRNA CTD PMID:20187946 NCBI chr10:101,243,146...101,247,323
Ensembl chr10:101,235,994...101,247,337 		JBrowse link
G Galnt1 polypeptide N-acetylgalactosaminyltransferase 1 increases expression EXP Cocaine results in increased expression of GALNT1 mRNA CTD PMID:17898221 NCBI chr18:15,489,015...15,568,849
Ensembl chr18:15,489,020...15,568,245 		JBrowse link
G Galnt16 polypeptide N-acetylgalactosaminyltransferase 16 affects expression EXP Cocaine affects the expression of GALNT16 mRNA CTD PMID:20187946 NCBI chr 6:100,168,943...100,250,718
Ensembl chr 6:100,170,306...100,250,705 		JBrowse link
G Gap43 growth associated protein 43 decreases expression ISO Cocaine results in decreased expression of GAP43 mRNA CTD PMID:12629581 NCBI chr11:58,376,371...58,470,047
Ensembl chr11:58,376,371...58,470,045 		JBrowse link
G Gas2 growth arrest-specific 2 affects expression ISO Cocaine affects the expression of GAS2 mRNA CTD PMID:15681117 NCBI chr 1:101,452,361...101,582,619
Ensembl chr 1:101,482,591...101,582,619 		JBrowse link
G Gcc1 GRIP and coiled-coil domain containing 1 increases expression ISO Cocaine results in increased expression of GCC1 mRNA CTD PMID:17205118 NCBI chr 4:57,030,817...57,042,682
Ensembl chr 4:57,032,314...57,042,663 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
multiple interactions		 ISO Cocaine results in increased expression of GCLC mRNA
PRKCD protein affects the reaction [Cocaine results in increased expression of GCLC mRNA]; rottlerin promotes the reaction [Cocaine results in increased expression of GCLC mRNA]		 CTD PMID:30393195 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit affects expression
multiple interactions
increases expression		 EXP
ISO		 Cocaine affects the expression of GCLM mRNA
PRKCD protein affects the reaction [Cocaine results in increased expression of GCLM mRNA]; rottlerin promotes the reaction [Cocaine results in increased expression of GCLM mRNA]		 CTD PMID:20187946 PMID:30393195 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 increases expression ISO Cocaine deficiency results in increased expression of GCNT2 mRNA CTD PMID:27126842 NCBI chr17:23,796,859...23,901,625
Ensembl chr17:23,796,859...23,901,611 		JBrowse link
G Gdap1 ganglioside-induced differentiation-associated-protein 1 increases expression EXP Cocaine results in increased expression of GDAP1 protein CTD PMID:25100957 NCBI chr 5:1,932,613...1,951,691
Ensembl chr 5:1,932,613...2,030,061 		JBrowse link
G Gdap1l1 ganglioside-induced differentiation-associated protein 1-like 1 decreases expression EXP Cocaine results in decreased expression of GDAP1L1 protein CTD PMID:25100957 NCBI chr 3:152,110,225...152,129,693
Ensembl chr 3:152,110,253...152,128,711 		JBrowse link
G Gdnf glial cell derived neurotrophic factor decreases expression EXP Cocaine results in decreased expression of GDNF mRNA CTD PMID:14622243 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle increases expression ISO Cocaine results in increased expression of GEM mRNA CTD PMID:15009677 NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:25,214,309...25,225,222 		JBrowse link
G Gfap glial fibrillary acidic protein increases expression
affects expression
decreases expression		 ISO
EXP		 Cocaine results in increased expression of GFAP protein
Cocaine affects the expression of GFAP protein
Cocaine affects the expression of GFAP mRNA; Cocaine affects the expression of GFAP protein
Cocaine results in decreased expression of GFAP protein		 CTD PMID:11391778 PMID:11882367 PMID:12670315 PMID:15814102 PMID:20187946 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589 		JBrowse link
G Gfra2 GDNF family receptor alpha 2 affects expression EXP Cocaine affects the expression of GFRA2 mRNA CTD PMID:12358776 NCBI chr15:45,941,841...46,033,715
Ensembl chr15:45,941,828...46,033,714 		JBrowse link
G Gh1 growth hormone 1 multiple interactions ISO
EXP		 Cocaine inhibits the reaction [4-hydroxybutyric acid results in increased secretion of GH1 protein]; Cocaine inhibits the reaction [Sodium Oxybate results in increased expression of GH1 protein]
Cocaine inhibits the reaction [Clonidine results in increased secretion of GH1 protein]		 CTD PMID:9413023 PMID:10657535 PMID:15099682 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078 		JBrowse link
G Gid8 GID complex subunit 8 homolog affects expression EXP Cocaine affects the expression of GID8 mRNA CTD PMID:20187946 NCBI chr 3:167,826,006...167,836,759
Ensembl chr 3:167,826,060...167,834,814 		JBrowse link
G Gimap1 GTPase, IMAP family member 1 affects expression EXP Cocaine affects the expression of GIMAP1 mRNA CTD PMID:20187946 NCBI chr 4:77,687,581...77,691,468
Ensembl chr 4:77,682,171...77,691,866 		JBrowse link
G Gimap5 GTPase, IMAP family member 5 affects expression EXP Cocaine affects the expression of GIMAP5 mRNA CTD PMID:20187946 NCBI chr 4:77,693,417...77,701,025
Ensembl chr 4:77,687,564...77,703,086 		JBrowse link
G Gins3 GINS complex subunit 3 decreases expression EXP Cocaine results in decreased expression of GINS3 mRNA CTD PMID:27899881 NCBI chr19:9,420,085...9,428,621
Ensembl chr19:9,420,086...9,428,687 		JBrowse link
G Gipc1 GIPC PDZ domain containing family, member 1 affects expression EXP Cocaine affects the expression of GIPC1 mRNA CTD PMID:20187946 NCBI chr19:24,474,291...24,487,083
Ensembl chr19:24,453,123...24,486,997 		JBrowse link
G Gja5 gap junction protein, alpha 5 increases expression EXP Cocaine results in increased expression of GJA5 mRNA CTD PMID:27899881 NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952 		JBrowse link
G Gjb1 gap junction protein, beta 1 affects expression EXP Cocaine affects the expression of GJB1 mRNA; Cocaine affects the expression of GJB1 protein CTD PMID:10510198 NCBI chr  X:66,501,848...66,509,783
Ensembl chr  X:66,501,820...66,509,925 		JBrowse link
G Gjb2 gap junction protein, beta 2 decreases expression ISO Cocaine results in decreased expression of GJB2 mRNA CTD PMID:12629581 NCBI chr15:31,260,390...31,278,222
Ensembl chr15:31,260,357...31,278,177 		JBrowse link
G Gjb5 gap junction protein, beta 5 decreases expression EXP Cocaine results in decreased expression of GJB5 mRNA CTD PMID:27899881 NCBI chr 5:139,680,670...139,683,588
Ensembl chr 5:139,680,671...139,683,583 		JBrowse link
G Gjd2 gap junction protein, delta 2 affects expression EXP Cocaine affects the expression of GJD2 mRNA; Cocaine affects the expression of GJD2 protein CTD PMID:16138316 NCBI chr 3:100,771,450...100,776,134
Ensembl chr 3:100,772,062...100,775,061 		JBrowse link
G Gli2 GLI family zinc finger 2 decreases expression EXP Cocaine results in decreased expression of GLI2 mRNA CTD PMID:27899881 NCBI chr13:29,946,882...30,163,589
Ensembl chr13:29,946,809...30,163,574 		JBrowse link
G Glp2r glucagon-like peptide 2 receptor decreases expression EXP Cocaine results in decreased expression of GLP2R mRNA CTD PMID:17898221 NCBI chr10:52,402,748...52,466,012
Ensembl chr10:52,402,748...52,466,012 		JBrowse link
G Glra1 glycine receptor, alpha 1 multiple interactions EXP Cocaine inhibits the reaction [Glycine results in increased activity of GLRA1 protein]; Dronabinol inhibits the reaction [Cocaine inhibits the reaction [Glycine results in increased activity of GLRA1 protein]] CTD PMID:32209479 NCBI chr10:39,625,853...39,727,897
Ensembl chr10:39,629,459...39,727,162 		JBrowse link
G Glrx3 glutaredoxin 3 affects expression EXP Cocaine affects the expression of GLRX3 mRNA CTD PMID:20187946 NCBI chr 1:192,241,707...192,272,012
Ensembl chr 1:192,241,701...192,272,010 		JBrowse link
G Gnao1 G protein subunit alpha o1 decreases expression
multiple interactions		 ISO
EXP		 Cocaine results in decreased expression of GNAO1 mRNA
[Cocaine affects the activity of PRKACA protein] which affects the phosphorylation of GNAO1 protein alternative form		 CTD PMID:12629581 PMID:19457111 NCBI chr19:11,034,874...11,192,531
Ensembl chr19:11,035,956...11,192,493 		JBrowse link
G Gnat1 G protein subunit alpha transducin 1 increases expression EXP Cocaine results in increased expression of GNAT1 mRNA CTD PMID:27899881 NCBI chr 8:108,350,935...108,355,671
Ensembl chr 8:108,350,935...108,355,671 		JBrowse link
G Gnb1 G protein subunit beta 1 decreases expression
increases expression		 ISO
EXP		 Cocaine results in decreased expression of GNB1 mRNA
Cocaine results in increased expression of GNB1 mRNA		 CTD PMID:12629581 PMID:16076954 NCBI chr 5:166,075,508...166,142,223
Ensembl chr 5:166,075,629...166,142,124 		JBrowse link
G Gnb2 G protein subunit beta 2 affects expression EXP Cocaine affects the expression of GNB2 mRNA CTD PMID:20187946 NCBI chr12:19,159,002...19,164,021
Ensembl chr12:19,158,973...19,164,019 		JBrowse link
G Gnb4 G protein subunit beta 4 multiple interactions ISO HDAC5 affects the reaction [Cocaine affects the expression of GNB4 mRNA] CTD PMID:17988634 NCBI chr 2:115,360,746...115,400,680
Ensembl chr 2:115,364,918...115,400,579 		JBrowse link
G Gng12 G protein subunit gamma 12 affects expression EXP Cocaine affects the expression of GNG12 mRNA CTD PMID:20187946 NCBI chr 4:96,011,118...96,134,767
Ensembl chr 4:96,010,952...96,134,712 		JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 decreases expression
multiple interactions		 ISO Cocaine results in decreased expression of GNRH1 protein
GPX1 protein inhibits the reaction [Cocaine results in decreased expression of GNRH1 protein]; prolinedithiocarbamate inhibits the reaction [Cocaine results in decreased expression of GNRH1 protein]		 CTD PMID:31059705 NCBI chr15:41,972,482...41,976,690
Ensembl chr15:41,972,905...41,973,581
Ensembl chr15:41,972,905...41,973,581 		JBrowse link
G Gp2 glycoprotein 2 affects expression EXP Cocaine affects the expression of GP2 mRNA CTD PMID:20187946 NCBI chr 1:173,797,057...173,812,619
Ensembl chr 1:173,797,057...173,812,619 		JBrowse link
G Gpc5 glypican 5 increases expression
multiple interactions		 ISO Cocaine results in increased expression of GPC5 mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of GPC5 mRNA]		 CTD PMID:18355967 NCBI chr15:92,207,275...93,644,054
Ensembl chr15:92,239,176...93,643,282 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 increases expression EXP Cocaine results in increased expression of GPER1 mRNA CTD PMID:17898221 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889 		JBrowse link
G Gphn gephyrin increases phosphorylation
multiple interactions		 EXP Cocaine results in increased phosphorylation of GPHN protein
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [Cocaine results in increased phosphorylation of GPHN protein]		 CTD PMID:32312805 NCBI chr 6:96,954,365...97,483,617
Ensembl chr 6:96,892,148...97,483,612 		JBrowse link
G Gpm6a glycoprotein m6a decreases expression ISO Cocaine results in decreased expression of GPM6A mRNA CTD PMID:12629581 NCBI chr16:36,641,282...36,973,377
Ensembl chr16:36,641,284...36,973,475 		JBrowse link
G Gpm6b glycoprotein m6b decreases expression ISO Cocaine results in decreased expression of GPM6B mRNA CTD PMID:12629581 NCBI chr  X:28,057,788...28,204,409
Ensembl chr  X:28,059,450...28,204,211 		JBrowse link
G Gpr157 G protein-coupled receptor 157 decreases expression EXP Cocaine results in decreased expression of GPR157 mRNA CTD PMID:27899881 NCBI chr 5:160,550,703...160,566,432
Ensembl chr 5:160,550,713...160,566,432 		JBrowse link
G Gpr3 G protein-coupled receptor 3 increases expression EXP Cocaine results in increased expression of GPR3 mRNA CTD PMID:27899881 NCBI chr 5:145,411,500...145,414,621
Ensembl chr 5:145,411,510...145,414,590 		JBrowse link
G Gpr88 G-protein coupled receptor 88 affects expression
increases expression		 EXP
ISO		 Cocaine affects the expression of GPR88 mRNA
Cocaine deficiency results in increased expression of GPR88 mRNA		 CTD PMID:20187946 PMID:27126842 NCBI chr 2:204,191,443...204,199,576
Ensembl chr 2:204,191,427...204,199,733 		JBrowse link
G Gprasp1 G protein-coupled receptor associated sorting protein 1 affects expression EXP Cocaine affects the expression of GPRASP1 mRNA CTD PMID:20187946 NCBI chr  X:98,764,853...98,772,685
Ensembl chr  X:98,709,841...98,772,851 		JBrowse link
G Gpsm1 G-protein signaling modulator 1 affects expression EXP Cocaine affects the expression of GPSM1 protein CTD PMID:15091342 NCBI chr 3:9,140,816...9,167,828
Ensembl chr 3:9,128,636...9,167,827 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases activity		 ISO PRKCD protein affects the reaction [Cocaine results in increased activity of GPT protein]; rottlerin inhibits the reaction [Cocaine results in increased activity of GPT protein] CTD PMID:30393195 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression
multiple interactions
affects response to substance		 ISO Cocaine results in increased expression of GPX1 protein
GPX1 affects the reaction [Cocaine results in increased activity of SOD1 protein]; GPX1 affects the reaction [Cocaine results in increased activity of SOD2 protein]; GPX1 affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; GPX1 affects the reaction [Cocaine results in increased cleavage of PRKCD protein]; GPX1 protein affects the susceptibility to [Cocaine co-treated with prolinedithiocarbamate]; GPX1 protein inhibits the reaction [Cocaine affects the localization of RELA protein]; GPX1 protein inhibits the reaction [Cocaine results in decreased expression of GNRH1 protein]; GPX1 protein inhibits the reaction [Cocaine results in increased activity of and affects the localization of RELA protein]; GPX1 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; prolinedithiocarbamate promotes the reaction [Cocaine results in increased expression of GPX1 protein]
GPX1 protein affects the susceptibility to Cocaine		 CTD PMID:30027653 PMID:31059705 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Grb2 growth factor receptor bound protein 2 increases expression EXP Cocaine results in increased expression of GRB2 protein CTD PMID:25100957 NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 decreases response to substance
increases expression
affects expression
multiple interactions
decreases phosphorylation
increases response to substance
affects response to substance
increases phosphorylation
decreases expression
increases expression
decreases expression 		ISO
EXP		 GRIA1 results in decreased susceptibility to Cocaine
Cocaine results in increased expression of GRIA1 protein
Cocaine affects the expression of GRIA1 mRNA
Cocaine results in increased expression of and results in increased phosphorylation of GRIA1 protein; Nifedipine inhibits the reaction [Cocaine results in increased expression of and results in increased phosphorylation of GRIA1 protein]; resveratrol promotes the reaction [Cocaine results in increased phosphorylation of GRIA1 protein]; SL 327 inhibits the reaction [Cocaine results in increased phosphorylation of GRIA1 protein]
Cocaine affects the expression of GRIA1 mRNA; Cocaine affects the expression of GRIA1 protein
6-methyl-2-(phenylethynyl)pyridine affects the reaction [Cocaine affects the phosphorylation of GRIA1 protein]; Cocaine affects the phosphorylation of and affects the expression of GRIA1 protein; Cocaine results in increased phosphorylation of and results in increased transport of GRIA1 protein; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of GRIA1 protein]; ifenprodil inhibits the reaction [Cocaine results in increased expression of GRIA1 protein]; ILK mutant form inhibits the reaction [Cocaine results in increased phosphorylation of GRIA1 protein]; Ondansetron inhibits the reaction [Cocaine results in increased phosphorylation of GRIA1 protein]; roscovitine inhibits the reaction [Cocaine results in decreased phosphorylation of GRIA1 protein]; U 0126 inhibits the reaction [Cocaine results in increased expression of GRIA1 protein]
Cocaine results in increased expression of GRIA1 mRNA; Cocaine results in increased expression of GRIA1 protein
GRIA1 protein mutant form results in decreased susceptibility to Cocaine; GRIA1 results in decreased susceptibility to Cocaine
GRIA1 protein results in increased susceptibility to Cocaine
GRIA1 protein affects the susceptibility to Cocaine
Cocaine results in decreased expression of GRIA1 mRNA; Cocaine results in decreased expression of GRIA1 protein
Cocaine increases expression of Gria1 mRNA in the nucleus accumbens
Cocaine increases expression of Gria1 protein in the ventral tegmental area
Cocaine increases phosphorylation of Gria1 protein in the hippocampal formation
Cocaine increases phosphorylation of Gria1 protein in the dorsal striatum
Cocaine decreases expression of Gria1 protein in the nucleus accumbens
Cocaine increases expression of Gria1 protein in the nucleus accumbens
Cocaine increases phosphorylation of Gria1 protein in the prefrontal cortex, premotor cortex
Cocaine increases phosphorylation of Gria1 protein in the shell of nucleus accumbens
Cocaine increases expression of Gria1 protein on nucleus accumbens cell surface
Cocaine increases phosphorylation of Gria1 protein in prefrontal cortex, nucleus accumbens		 CTD
RGD		 PMID:9886066 PMID:11268215 PMID:11801363 PMID:12511956 PMID:12787079 More... RGD:405096667, RGD:405649733, RGD:405649734, RGD:405649862, RGD:405650197, RGD:405650201, RGD:405650586, RGD:405650670, RGD:405650685, RGD:405818274, RGD:405820206, RGD:405820210 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 increases expression
affects expression
multiple interactions
decreases response to substance		 ISO
EXP		 Cocaine results in increased expression of GRIA2 protein
Cocaine affects the expression of GRIA2 mRNA; Cocaine affects the expression of GRIA2 protein
Cocaine results in increased expression of GRIA2 mRNA
Cocaine results in increased phosphorylation of and affects the localization of GRIA2 protein
GRIA2 results in decreased susceptibility to Cocaine		 CTD PMID:9886066 PMID:12511956 PMID:12787079 PMID:15140200 PMID:16363995 More... NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510 		JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 decreases expression
increases expression
affects expression		 ISO
EXP		 Cocaine results in decreased expression of GRIA3 mRNA
Cocaine results in increased expression of GRIA3 protein
Cocaine affects the expression of GRIA3 protein		 CTD PMID:9886066 PMID:12511956 PMID:15140200 PMID:16363995 NCBI chr  X:120,238,515...120,504,106
Ensembl chr  X:120,238,534...120,504,096 		JBrowse link
G Gria4 glutamate ionotropic receptor AMPA type subunit 4 affects expression ISO
EXP		 Cocaine affects the expression of GRIA4 mRNA
Cocaine affects the expression of GRIA4 protein		 CTD PMID:9886066 PMID:15140200 NCBI chr 8:1,562,118...2,035,035
Ensembl chr 8:1,562,119...2,034,979 		JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 affects expression EXP Cocaine affects the expression of GRIK1 mRNA; Cocaine affects the expression of GRIK1 protein CTD PMID:12358776 PMID:15140200 NCBI chr11:27,169,739...27,571,131
Ensembl chr11:27,169,740...27,570,645 		JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 affects expression EXP Cocaine affects the expression of GRIK2 protein CTD PMID:15140200 NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375 		JBrowse link
G Grik3 glutamate ionotropic receptor kainate type subunit 3 affects expression EXP Cocaine affects the expression of GRIK3 protein CTD PMID:15140200 NCBI chr 5:137,767,865...137,989,617
Ensembl chr 5:137,767,865...137,984,307 		JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 affects expression EXP Cocaine affects the expression of GRIK5 protein CTD PMID:15140200 NCBI chr 1:80,605,878...80,667,896
Ensembl chr 1:80,605,892...80,667,125 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 multiple interactions
increases expression
decreases expression
affects expression
affects phosphorylation
affects response to substance		 EXP
ISO		 6-methyl-2-(phenylethynyl)pyridine affects the reaction [Cocaine affects the phosphorylation of GRIN1 protein]; Cocaine affects the phosphorylation of and affects the expression of GRIN1 protein; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of GRIN1 protein]; ifenprodil inhibits the reaction [Cocaine results in increased expression of GRIN1 protein]
Cocaine results in decreased expression of GRIN1 mRNA
Cocaine affects the expression of GRIN1 mRNA; Cocaine affects the expression of GRIN1 protein
Cocaine results in increased expression of GRIN1 mRNA; Cocaine results in increased expression of GRIN1 protein
GRIN1 protein affects the susceptibility to Cocaine		 CTD PMID:9886066 PMID:11032893 PMID:11801363 PMID:12457264 PMID:12670717 More... NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A multiple interactions
affects expression
increases expression		 ISO
EXP		 HDAC5 affects the reaction [Cocaine affects the expression of GRIN2A mRNA]
Cocaine affects the expression of GRIN2A mRNA; Cocaine affects the expression of GRIN2A protein
Cocaine results in increased expression of GRIN2A mRNA; Cocaine results in increased expression of GRIN2A protein
ifenprodil inhibits the reaction [Cocaine results in increased expression of GRIN2A protein]		 CTD PMID:17898221 PMID:17988634 PMID:19105975 PMID:19306440 PMID:19474322 More... NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B increases expression
decreases phosphorylation
affects expression
multiple interactions
affects response to substance		 EXP Cocaine results in increased expression of GRIN2B protein
Cocaine results in decreased phosphorylation of GRIN2B protein
Cocaine affects the expression of GRIN2B mRNA; Cocaine affects the expression of GRIN2B protein
Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of GRIN2B protein]; ifenprodil inhibits the reaction [Cocaine results in increased expression of GRIN2B protein]; Ondansetron inhibits the reaction [Cocaine results in decreased phosphorylation of GRIN2B protein]; Ondansetron inhibits the reaction [Cocaine results in increased expression of GRIN2B protein]
GRIN2B protein affects the susceptibility to Cocaine		 CTD PMID:11032893 PMID:11801363 PMID:15140200 PMID:16794574 PMID:19105975 More... NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C affects expression EXP Cocaine affects the expression of GRIN2C mRNA CTD PMID:20187946 NCBI chr10:100,488,430...100,507,083
Ensembl chr10:100,488,431...100,506,427 		JBrowse link
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D increases expression
affects expression		 EXP Cocaine results in increased expression of GRIN2D mRNA
Cocaine affects the expression of GRIN2D mRNA		 CTD PMID:16076954 PMID:20187946 NCBI chr 1:96,306,871...96,346,994
Ensembl chr 1:96,308,365...96,344,793 		JBrowse link
G Grin3a glutamate ionotropic receptor NMDA type subunit 3A affects expression EXP Cocaine affects the expression of GRIN3A protein CTD PMID:15140200 NCBI chr 5:64,006,847...64,206,408
Ensembl chr 5:64,009,980...64,206,085 		JBrowse link
G Grin3b glutamate ionotropic receptor NMDA type subunit 3B affects expression EXP Cocaine affects the expression of GRIN3B protein CTD PMID:15140200 NCBI chr 7:9,730,861...9,737,183
Ensembl chr 7:9,730,862...9,737,183 		JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 increases expression EXP Cocaine results in increased expression of GRINA mRNA CTD PMID:16076954 NCBI chr 7:107,962,194...107,965,372
Ensembl chr 7:107,962,207...107,965,366 		JBrowse link
G Grip1 glutamate receptor interacting protein 1 increases phosphorylation
multiple interactions		 EXP
ISO		 Cocaine results in increased phosphorylation of GRIP1 protein
[Cocaine co-treated with FOS protein mutant form] results in increased expression of GRIP1 mRNA		 CTD PMID:18355967 PMID:19439608 NCBI chr 7:54,934,856...55,592,274
Ensembl chr 7:54,934,250...55,592,273 		JBrowse link
G Grip2 glutamate receptor interacting protein 2 increases expression EXP Cocaine results in increased expression of GRIP2 mRNA CTD PMID:16076954 NCBI chr 4:124,271,456...124,356,538
Ensembl chr 4:124,271,456...124,321,268 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 affects expression
increases expression		 EXP Cocaine affects the expression of GRK2 mRNA
Cocaine results in increased expression of GRK2 mRNA		 CTD PMID:16076954 PMID:20187946 NCBI chr 1:201,580,823...201,601,580
Ensembl chr 1:201,581,480...201,601,582 		JBrowse link
G Grk6 G protein-coupled receptor kinase 6 affects expression EXP Cocaine affects the expression of GRK6 mRNA CTD PMID:20187946 NCBI chr17:9,177,018...9,192,813
Ensembl chr17:9,177,019...9,192,644 		JBrowse link
G Grm1 glutamate metabotropic receptor 1 affects response to substance ISO GRM1 affects the susceptibility to Cocaine CTD PMID:19597494 NCBI chr 1:5,058,285...5,453,170
Ensembl chr 1:5,058,292...5,453,170 		JBrowse link
G Grm2 glutamate metabotropic receptor 2 increases activity
decreases activity
affects expression		 EXP Cocaine results in increased activity of GRM2 protein
Cocaine results in decreased activity of GRM2 protein
Cocaine affects the expression of GRM2 protein		 CTD PMID:18673447 PMID:19105975 PMID:20416862 NCBI chr 8:107,280,099...107,293,159
Ensembl chr 8:107,280,099...107,293,146 		JBrowse link
G Grm3 glutamate metabotropic receptor 3 increases activity
affects expression		 EXP Cocaine results in increased activity of GRM3 protein
Cocaine affects the expression of GRM3 protein		 CTD PMID:19105975 PMID:20416862 NCBI chr 4:24,364,854...24,643,972
Ensembl chr 4:24,365,115...24,609,804 		JBrowse link
G Grm5 glutamate metabotropic receptor 5 affects expression
decreases response to substance
affects localization
increases expression
multiple interactions		 ISO
EXP		 Cocaine affects the expression of GRM5 mRNA
GRM5 mutant form results in decreased susceptibility to Cocaine
Cocaine affects the localization of GRM5 protein
Cocaine affects the expression of GRM5 protein
Cocaine results in increased expression of GRM5 mRNA
Cocaine results in decreased expression of and results in decreased activity of GRM5 protein
Cocaine deficiency results in increased expression of GRM5 mRNA		 CTD PMID:9886066 PMID:15295029 PMID:17898221 PMID:19105975 PMID:19118598 More... NCBI chr 1:141,310,069...141,884,980
Ensembl chr 1:141,312,368...141,882,274 		JBrowse link
G Grm7 glutamate metabotropic receptor 7 increases expression EXP Cocaine results in increased expression of GRM7 mRNA CTD PMID:16076954 NCBI chr 4:143,730,862...144,613,230
Ensembl chr 4:143,731,259...144,612,344 		JBrowse link
G Grpr gastrin releasing peptide receptor affects expression EXP Cocaine affects the expression of GRPR mRNA CTD PMID:20187946 NCBI chr  X:30,998,425...31,038,442
Ensembl chr  X:30,998,416...31,038,442 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha affects expression EXP Cocaine affects the expression of GSK3A mRNA CTD PMID:12117546 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases activity		 ISO Cocaine results in decreased phosphorylation of and results in increased activity of GSK3B protein
Cocaine results in increased activity of GSK3B protein		 CTD PMID:19328817 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gsn gelsolin decreases expression ISO Cocaine results in decreased expression of GSN mRNA CTD PMID:12629581 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402 		JBrowse link
G Gsr glutathione-disulfide reductase increases expression EXP Cocaine deficiency results in increased expression of GSR mRNA CTD PMID:22860061 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Gsto1 glutathione S-transferase omega 1 affects expression ISO Cocaine affects the expression of GSTO1 protein CTD PMID:19393250 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 affects response to substance ISO GSTP1 polymorphism affects the susceptibility to Cocaine CTD PMID:16272961 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 increases expression EXP Cocaine results in increased expression of GUCY1A1 mRNA CTD PMID:17898221 NCBI chr 2:167,418,615...167,482,293
Ensembl chr 2:167,418,640...167,481,671 		JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 increases expression EXP Cocaine results in increased expression of GUCY1B1 mRNA CTD PMID:17898221 NCBI chr 2:167,348,824...167,398,983
Ensembl chr 2:167,348,825...167,398,916 		JBrowse link
G Gyg1 glycogenin 1 decreases expression EXP Cocaine results in decreased expression of GYG1 protein CTD PMID:25100957 NCBI chr 2:102,611,888...102,653,916
Ensembl chr 2:102,598,496...102,653,797 		JBrowse link
G Gzmm granzyme M affects expression EXP Cocaine affects the expression of GZMM mRNA CTD PMID:20187946 NCBI chr 7:10,011,065...10,016,841
Ensembl chr 7:10,011,066...10,016,665 		JBrowse link
G Hand1 heart and neural crest derivatives expressed 1 affects expression EXP Cocaine affects the expression of HAND1 mRNA CTD PMID:20187946 NCBI chr10:42,006,646...42,009,213
Ensembl chr10:42,006,651...42,009,213 		JBrowse link
G Hbb-b2 hemoglobin, beta adult minor chain increases expression ISO Cocaine results in increased expression of HBB-B2 protein modified form CTD PMID:24096156 NCBI chr 1:158,243,696...158,245,076
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Hcn2 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 increases expression ISO Cocaine results in increased expression of HCN2 mRNA CTD PMID:18000554 NCBI chr 7:9,969,801...9,988,839
Ensembl chr 7:9,970,368...9,988,841 		JBrowse link
G Hcrt hypocretin neuropeptide precursor affects expression
multiple interactions		 EXP Cocaine affects the expression of HCRT mRNA
Methadone affects the reaction [Cocaine affects the expression of HCRT mRNA]		 CTD PMID:18990547 NCBI chr10:85,689,979...85,691,214
Ensembl chr10:85,689,465...85,691,210 		JBrowse link
G Hcrtr2 hypocretin receptor 2 affects expression EXP Cocaine affects the expression of HCRTR2 protein CTD PMID:17623047 NCBI chr 8:76,989,834...77,105,953
Ensembl chr 8:76,989,834...77,105,893 		JBrowse link
G Hdac10 histone deacetylase 10 affects expression EXP Cocaine affects the expression of HDAC10 mRNA CTD PMID:20187946 NCBI chr 7:120,199,126...120,205,850
Ensembl chr 7:120,199,129...120,204,228 		JBrowse link
G Hdac5 histone deacetylase 5 decreases activity
multiple interactions
decreases response to substance		 ISO Cocaine results in decreased activity of HDAC5 protein
Cocaine results in increased phosphorylation of and results in increased localization of HDAC5 protein; HDAC5 affects the reaction [Cocaine affects the expression of ABCA5 mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of ADAM1A mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of CUEDC1 mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of ERBIN mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of GNB4 mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of GRIN2A mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of KCNK4 mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of KCNQ5 mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of PRM1 mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of RAPGEF6 mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of RGS20 mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of SUV39H1 mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of TACR1 mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of WNT5A mRNA]
HDAC5 results in decreased susceptibility to Cocaine		 CTD PMID:17988634 NCBI chr10:87,152,978...87,187,921
Ensembl chr10:87,152,978...87,188,235 		JBrowse link
G Hdac6 histone deacetylase 6 multiple interactions
decreases expression		 EXP (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [Cocaine results in decreased expression of HDAC6 protein] CTD PMID:32312805 NCBI chr  X:14,550,645...14,572,445
Ensembl chr  X:14,551,044...14,572,441 		JBrowse link
G Hdc histidine decarboxylase affects response to substance ISO HDC gene mutant form affects the susceptibility to Cocaine CTD PMID:17072589 NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341 		JBrowse link
G Hecw2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 decreases expression EXP Cocaine results in decreased expression of HECW2 mRNA CTD PMID:17898221 NCBI chr 9:55,359,462...55,753,106
Ensembl chr 9:55,365,203...55,580,327 		JBrowse link
G Herc1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 increases expression EXP Cocaine results in increased expression of HERC1 mRNA CTD PMID:17898221 NCBI chr 8:66,857,169...67,070,318
Ensembl chr 8:66,856,935...67,070,312 		JBrowse link
G Hhip Hedgehog-interacting protein decreases expression EXP Cocaine results in decreased expression of HHIP mRNA CTD PMID:17898221 NCBI chr19:27,863,684...27,952,528
Ensembl chr19:27,863,213...27,952,528 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases expression ISO Cocaine results in decreased expression of HIF1A mRNA CTD PMID:12629581 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Higd1a HIG1 hypoxia inducible domain family, member 1A affects expression
increases expression		 EXP Cocaine affects the expression of HIGD1A mRNA
Cocaine results in increased expression of HIGD1A protein		 CTD PMID:20187946 PMID:25100957 NCBI chr 8:121,514,152...121,523,382
Ensembl chr 8:121,514,156...121,523,443 		JBrowse link
G Hmga1 high mobility group AT-hook 1 affects expression EXP Cocaine affects the expression of HMGA1 mRNA CTD PMID:20187946 NCBI chr20:5,611,088...5,618,755
Ensembl chr20:5,611,694...5,618,752 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression EXP Cocaine results in increased expression of HMGCS1 mRNA CTD PMID:12117546 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100 		JBrowse link
G Homer1 homer scaffold protein 1 increases response to substance
increases expression
decreases response to substance
multiple interactions
affects expression		 ISO
EXP		 HOMER1 polymorphism results in increased susceptibility to Cocaine
Cocaine results in increased expression of HOMER1 mRNA
HOMER1 protein results in decreased susceptibility to Cocaine
Cocaine affects the expression of and affects the localization of HOMER1 protein
Cocaine affects the expression of HOMER1 mRNA; Cocaine affects the expression of HOMER1 protein
Cocaine results in increased expression of HOMER1 protein		 CTD PMID:15294147 PMID:16314758 PMID:18355967 PMID:19105975 PMID:19118598 More... NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785 		JBrowse link
G Homer2 homer scaffold protein 2 multiple interactions
decreases expression
decreases response to substance
affects expression		 ISO
EXP		 Cocaine affects the reaction [HOMER2 mutant form results in decreased secretion of Excitatory Amino Acid Agents]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of HOMER2 mRNA]
HOMER2 protein results in decreased susceptibility to Cocaine; HOMER2 results in decreased susceptibility to Cocaine
Cocaine affects the expression of HOMER2 mRNA		 CTD PMID:14684444 PMID:15294147 PMID:15545022 PMID:18355967 PMID:20187946 NCBI chr 1:135,558,977...135,659,780
Ensembl chr 1:135,567,414...135,659,772 		JBrowse link
G Homer3 homer scaffold protein 3 affects expression EXP Cocaine affects the expression of HOMER3 mRNA CTD PMID:20187946 NCBI chr16:19,132,177...19,142,739
Ensembl chr16:19,132,162...19,142,680 		JBrowse link
G Hpca hippocalcin increases expression ISO Cocaine deficiency results in increased expression of HPCA mRNA CTD PMID:27126842 NCBI chr 5:141,455,616...141,466,252
Ensembl chr 5:141,455,613...141,463,841 		JBrowse link
G Hpcal1 hippocalcin-like 1 decreases expression ISO Cocaine results in decreased expression of HPCAL1 mRNA CTD PMID:15009677 NCBI chr 6:40,478,206...40,584,721
Ensembl chr 6:40,478,208...40,584,687 		JBrowse link
G Hpcal4 hippocalcin-like 4 affects expression
increases expression		 EXP Cocaine affects the expression of HPCAL4 mRNA
Cocaine results in increased expression of HPCAL4 mRNA		 CTD PMID:17898221 PMID:20187946 NCBI chr 5:135,454,477...135,466,417
Ensembl chr 5:135,454,540...135,466,416 		JBrowse link
G Hpd 4-hydroxyphenylpyruvate dioxygenase increases expression EXP Cocaine results in increased expression of HPD mRNA CTD PMID:27899881 NCBI chr12:33,381,397...33,392,750
Ensembl chr12:33,381,231...33,392,766 		JBrowse link
G Hps1 HPS1, biogenesis of lysosomal organelles complex 3 subunit 1 affects expression EXP Cocaine affects the expression of HPS1 mRNA CTD PMID:20187946 NCBI chr 1:241,551,180...241,577,292
Ensembl chr 1:241,551,175...241,577,268 		JBrowse link
G Hs3st2 heparan sulfate-glucosamine 3-sulfotransferase 2 decreases expression
multiple interactions		 ISO Cocaine results in decreased expression of HS3ST2 mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of HS3ST2 mRNA]		 CTD PMID:18355967 NCBI chr 1:175,956,161...176,077,400
Ensembl chr 1:175,956,157...176,077,399 		JBrowse link
G Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6 decreases expression EXP Cocaine results in decreased expression of HSD17B6 mRNA CTD PMID:17898221 NCBI chr 7:422,466...442,008
Ensembl chr 7:422,480...442,425 		JBrowse link
G Hsf1 heat shock transcription factor 1 affects expression EXP Cocaine affects the expression of HSF1 mRNA CTD PMID:20187946 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression EXP Cocaine deficiency results in increased expression of HSP90AA1 mRNA CTD PMID:22860061 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 decreases expression EXP Cocaine results in decreased expression of HSP90AB1 mRNA CTD PMID:17898221 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression ISO Cocaine results in increased expression of HSPA1A mRNA CTD PMID:20056891 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B affects expression
increases expression		 ISO
EXP		 Cocaine affects the expression of HSPA1B mRNA
Cocaine results in increased expression of HSPA1B mRNA		 CTD PMID:15681117 PMID:27899881 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions		 ISO
EXP		 Cocaine results in increased expression of HSPA5 mRNA
6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Cocaine results in increased expression of HSPA5 protein]; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of HSPA5 protein]; N-phenyl-7-(hydroxyimino)cyclopropa(b)chromen-1a-carboxamide inhibits the reaction [Cocaine results in increased expression of HSPA5 protein]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of HSPA5 protein]
Cocaine results in increased expression of HSPA5 mRNA; Cocaine results in increased expression of HSPA5 protein		 CTD PMID:15009677 PMID:17303341 PMID:23644055 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 multiple interactions
increases expression		 EXP Anisomycin inhibits the reaction [Cocaine results in increased expression of HSPA9 protein] CTD PMID:12422371 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression EXP Cocaine results in increased expression of HSPB1 mRNA CTD PMID:27899881 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 affects expression ISO Cocaine affects the expression of HSPD1 protein CTD PMID:19393250 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662 		JBrowse link
G Htatsf1 HIV-1 Tat specific factor 1 multiple interactions EXP [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone co-treated with Cocaine] results in decreased phosphorylation of HTATSF1 protein CTD PMID:32312805 NCBI chr  X:134,935,426...134,949,607
Ensembl chr  X:134,935,426...134,949,607 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions EXP
ISO		 Cocaine inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to HTR1A protein]
Cocaine inhibits the reaction [Chronic constriction injury increases expression of Htr1a protein in dorsal raphe nucleus]		 CTD
RGD		 PMID:9723786 PMID:31045847 RGD:405849276 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B increases response to substance
multiple interactions
affects activity		 ISO
EXP		 HTR1B mutant form results in increased susceptibility to Cocaine
[3-(1,2,5,6-tetrahydropyrid-4-yl)pyrrolo(3,2-b)pyrid-5-one binds to and results in increased activity of HTR1B protein] which affects the susceptibility to Cocaine; [5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1H indole binds to and results in increased activity of HTR1B protein] which affects the susceptibility to Cocaine; [CP 94253 binds to and results in increased activity of HTR1B protein] which affects the susceptibility to Cocaine
Cocaine affects the activity of HTR1B protein		 CTD PMID:9603521 PMID:9822762 PMID:17074068 NCBI chr 8:82,513,572...82,534,670
Ensembl chr 8:82,517,360...82,534,549 		JBrowse link
G Htr1d 5-hydroxytryptamine receptor 1D affects expression EXP Cocaine affects the expression of HTR1D mRNA CTD PMID:20187946 NCBI chr 5:148,656,252...148,676,532
Ensembl chr 5:148,674,495...148,675,619 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A multiple interactions
affects response to substance
affects activity		 ISO
EXP		 [alpha-phenyl-1-(2-phenylethyl)-4-piperidinemethanol binds to and results in decreased activity of HTR2A protein] which results in decreased susceptibility to Cocaine; [Alprenolol co-treated with Cocaine] affects the reaction [HTR2A protein results in increased susceptibility to 4-iodo-2,5-dimethoxyphenylisopropylamine]; [Metergoline binds to and results in decreased activity of HTR2A protein] which results in decreased susceptibility to Cocaine; [Methiothepin binds to and results in decreased activity of HTR2A protein] which results in decreased susceptibility to Cocaine; [Mianserin binds to and results in decreased activity of HTR2A protein] which results in decreased susceptibility to Cocaine; [Yohimbine co-treated with Cocaine] affects the reaction [HTR2A protein results in increased susceptibility to 4-iodo-2,5-dimethoxyphenylisopropylamine]; Cocaine inhibits the reaction [HTR2A protein results in increased susceptibility to 4-iodo-2,5-dimethoxyphenylisopropylamine]
HTR2A protein affects the susceptibility to Cocaine
Cocaine promotes the reaction [[4-iodo-2,5-dimethoxyphenylisopropylamine binds to and results in increased activity of HTR2A protein] which results in increased secretion of and results in increased abundance of Dopamine]; Ketanserin inhibits the reaction [Cocaine promotes the reaction [[4-iodo-2,5-dimethoxyphenylisopropylamine binds to and results in increased activity of HTR2A protein] which results in increased secretion of and results in increased abundance of Dopamine]]
Cocaine affects the activity of HTR2A protein		 CTD PMID:8392199 PMID:10764922 PMID:10773209 PMID:10773215 PMID:17259860 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C multiple interactions
increases response to substance
decreases expression		 ISO
EXP		 [1-(3-chlorophenyl)piperazine binds to and results in increased activity of HTR2C protein] which results in increased susceptibility to Cocaine; [6-chloro-2-(1-piperazinyl)pyrazine binds to and results in increased activity of HTR2C protein] which results in increased susceptibility to Cocaine; HTR2C protein affects the reaction [Cocaine results in increased abundance of Dopamine]
HTR2C mutant form results in increased susceptibility to Cocaine
Cocaine results in decreased expression of HTR2C mRNA		 CTD PMID:10541732 PMID:12427861 PMID:16076954 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A decreases response to substance
multiple interactions		 ISO
EXP		 HTR3A mutant form results in decreased susceptibility to Cocaine
Cocaine inhibits the reaction [Serotonin results in increased activity of HTR3A protein]		 CTD PMID:17559417 PMID:32209479 NCBI chr 8:49,242,018...49,254,475
Ensembl chr 8:49,242,020...49,254,389 		JBrowse link
G Htr4 5-hydroxytryptamine receptor 4 affects response to substance EXP HTR4 protein affects the susceptibility to Cocaine CTD PMID:9806222 NCBI chr18:55,765,981...55,949,921
Ensembl chr18:55,766,725...55,949,321 		JBrowse link
G Htr6 5-hydroxytryptamine receptor 6 multiple interactions EXP [Ro 4-6790 binds to and results in decreased activity of HTR6 protein] which results in decreased susceptibility to Cocaine; [SB 271046 binds to and results in decreased activity of HTR6 protein] which results in decreased susceptibility to Cocaine CTD PMID:20426879 NCBI chr 5:151,295,269...151,312,853
Ensembl chr 5:151,296,662...151,311,912 		JBrowse link
G Hvcn1 hydrogen voltage-gated channel 1 decreases expression EXP Cocaine results in decreased expression of HVCN1 mRNA CTD PMID:27899881 NCBI chr12:34,341,673...34,370,010
Ensembl chr12:34,335,190...34,370,141 		JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression EXP Cocaine results in increased expression of ICAM1 mRNA CTD PMID:10864098 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Ice2 interactor of little elongation complex ELL subunit 2 affects response to substance ISO ICE2 gene SNP affects the susceptibility to Cocaine CTD PMID:18438686 NCBI chr 8:70,043,419...70,085,217
Ensembl chr 8:70,043,424...70,084,995 		JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha affects expression EXP Cocaine affects the expression of IDH3A mRNA CTD PMID:20187946 NCBI chr 8:54,971,694...54,991,085
Ensembl chr 8:54,971,740...54,991,084 		JBrowse link
G Ier5 immediate early response 5 affects expression EXP Cocaine affects the expression of IER5 mRNA CTD PMID:20187946 NCBI chr13:67,270,134...67,272,226
Ensembl chr13:67,270,135...67,272,227 		JBrowse link
G Ifng interferon gamma affects secretion
decreases expression
multiple interactions		 ISO Cocaine affects the secretion of IFNG protein
Cocaine results in decreased expression of IFNG protein
[Cocaine co-treated with Heroin] results in increased expression of IFNG protein
Cocaine results in decreased expression of IFNG mRNA; Cocaine results in decreased expression of IFNG protein		 CTD PMID:9787120 PMID:16766138 PMID:29673861 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Ifrd1 interferon-related developmental regulator 1 affects expression EXP Cocaine affects the expression of IFRD1 mRNA CTD PMID:20187946 NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990 		JBrowse link
G Ift81 intraflagellar transport 81 increases expression EXP Cocaine results in increased expression of IFT81 mRNA CTD PMID:17898221 NCBI chr12:33,957,744...34,037,164
Ensembl chr12:33,957,806...34,037,057 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor affects expression EXP Cocaine affects the expression of IGF1R mRNA CTD PMID:20187946 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Igf2 insulin-like growth factor 2 decreases expression EXP Cocaine results in decreased expression of IGF2 mRNA CTD PMID:16076954 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018 		JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 decreases expression EXP Cocaine results in decreased expression of IGFBP2 mRNA CTD PMID:16076954 NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937 		JBrowse link
G Igsf8 immunoglobulin superfamily, member 8 affects expression EXP Cocaine affects the expression of IGSF8 mRNA CTD PMID:20187946 NCBI chr13:84,770,348...84,781,534
Ensembl chr13:84,770,279...84,778,576 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta affects expression EXP Cocaine affects the expression of IKBKB mRNA CTD PMID:20187946 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250 		JBrowse link
G Il10 interleukin 10 multiple interactions
decreases secretion
increases expression		 ISO [Cocaine co-treated with Heroin] results in increased expression of IL10 protein
Cocaine results in decreased secretion of IL10 protein
Cocaine results in increased expression of IL10 protein		 CTD PMID:9787120 PMID:16766138 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il16 interleukin 16 decreases expression EXP Cocaine results in decreased expression of IL16 mRNA CTD PMID:27899881 NCBI chr 1:137,617,702...137,718,022
Ensembl chr 1:137,617,944...137,718,130 		JBrowse link
G Il18bp interleukin 18 binding protein affects expression EXP Cocaine affects the expression of IL18BP mRNA CTD PMID:20187946 NCBI chr 1:156,372,923...156,374,963
Ensembl chr 1:156,372,883...156,374,963 		JBrowse link
G Il1a interleukin 1 alpha affects expression EXP Cocaine affects the expression of IL1A mRNA CTD PMID:20187946 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta increases expression ISO Cocaine results in increased expression of IL1B mRNA CTD PMID:20948987 PMID:26558777 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il2 interleukin 2 multiple interactions ISO [Cocaine co-treated with Heroin] results in increased expression of IL2 protein CTD PMID:16766138 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link