cyanidin cation - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	cyanidin cation	go back to main search page
Accession:	CHEBI:27843	browse the term
Definition:	An anthocyanidin cation that is flavylium substituted at positions 3, 3', 4', 5 and 7 by hydroxy groups.
Synonyms:	exact_synonym:	2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychromenium
	related_synonym:	2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-1-Benzopyrylium; 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychromenylium; 3,5,7,3',4'-Pentahydroxyflavylium; Cyanidin; Cyanidine; Cyanidol; Formula=C15H11O6; InChI=1S/C15H10O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-6H,(H4-,16,17,18,19,20)/p+1; InChIKey=VEVZSMAEJFVWIL-UHFFFAOYSA-O; SMILES=Oc1cc(O)c2cc(O)c([o+]c2c1)-c1ccc(O)c(O)c1
	alt_id:	CHEBI:23425; CHEBI:3970
	xref:	Beilstein:1690254; CAS:13306-05-3; KEGG:C05905; KNApSAcK:C00006614; LIPID_MAPS_instance:LMPK12010002
	xref_mesh:	MESH:C017154
	xref:	MetaCyc:CPD-591; PMID:23123597; PMID:23360684; PMID:23375153; PMID:23389674; Reaxys:1690254; Wikipedia:Cyanidin
	cyclic_relationship:	is_conjugate_acid_of CHEBI:71682

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Genes (30)

cyanidin cation

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

acetylcholinesterase

decreases activity

EXP

cyanidin results in decreased activity of ACHE protein

NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410

G

aryl hydrocarbon receptor

increases activity

ISO

cyanidin results in increased activity of AHR protein

NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901

G

cellular communication network factor 1

multiple interactions

ISO
EXP

cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of CCN1 protein]
cyanidin inhibits the reaction [Freund's Adjuvant results in increased expression of CCN1 protein]

NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:237,222,432...237,225,883

G

colony stimulating factor 2

multiple interactions

EXP
ISO

cyanidin inhibits the reaction [Freund's Adjuvant results in increased expression of CSF2 protein]
cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of CSF2 mRNA]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of CSF2 protein]

NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031

G

catenin beta 1

multiple interactions

EXP

cyanidin promotes the reaction [bisphenol A results in increased expression of CTNNB1 mRNA]

NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662

G

dickkopf WNT signaling pathway inhibitor 1

multiple interactions

EXP

cyanidin inhibits the reaction [bisphenol A results in increased expression of DKK1 mRNA]

NCBI chr 1:237,794,969...237,798,650
Ensembl chr 1:237,794,969...237,798,650

G

glycogen synthase kinase 3 beta

multiple interactions

EXP

cyanidin inhibits the reaction [bisphenol A results in increased expression of GSK3B mRNA]

NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249

G

heparin-binding EGF-like growth factor

multiple interactions

ISO

cyanidin inhibits the reaction [Sodium Chloride results in increased expression of HBEGF mRNA]

NCBI chr18:28,380,337...28,390,220
Ensembl chr18:28,380,337...28,390,220

G

holocarboxylase synthetase

decreases activity

ISO

cyanidin results in decreased activity of HLCS protein

NCBI chr11:46,925,491...47,123,111
Ensembl chr11:46,925,491...47,105,082

G

heme oxygenase 1

affects expression

ISO

cyanidin affects the expression of HMOX1 protein

NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818

G

interleukin 17A

multiple interactions

ISO

[cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of and results in increased phosphorylation of STAT3 protein]] which results in increased expression of PIAS3 protein; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of and results in increased phosphorylation of STAT3 protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of CCN1 protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of CSF2 mRNA]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of CSF2 protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL17RA mRNA]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL17RA protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL23A mRNA]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL23A protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of PCNA protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of TLR3 protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased phosphorylation of JAK1 protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased phosphorylation of JAK3 protein]; cyanidin inhibits the reaction [IL17A protein promotes the reaction [Freund's Adjuvant results in increased expression of TLR3 protein]]

NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:30,640,844...30,644,331

G

interleukin 17 receptor A

multiple interactions

ISO

cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL17RA mRNA]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL17RA protein]

NCBI chr 4:155,339,742...155,362,382
Ensembl chr 4:155,339,400...155,362,382

G

interleukin 23 subunit alpha

multiple interactions

ISO
EXP

cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL23A mRNA]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL23A protein]
cyanidin inhibits the reaction [Freund's Adjuvant results in increased expression of IL23A protein]

NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:1,306,320...1,308,434

G

Janus kinase 1

multiple interactions

ISO

cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased phosphorylation of JAK1 protein]

NCBI chr 5:120,895,606...121,004,207
Ensembl chr 5:120,896,046...120,996,758

G

Janus kinase 3

multiple interactions

ISO

cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased phosphorylation of JAK3 protein]

NCBI chr16:18,418,807...18,432,515
Ensembl chr16:18,420,415...18,433,222

G

microtubule-associated protein tau

multiple interactions

EXP

cyanidin inhibits the reaction [bisphenol A results in increased phosphorylation of MAPT protein]

NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,638,599...89,736,108

G

neuronal differentiation 1

multiple interactions

EXP

cyanidin promotes the reaction [bisphenol A results in increased expression of NEUROD1 mRNA]

NCBI chr 3:84,766,483...84,770,454
Ensembl chr 3:84,764,725...84,770,810

G

NFE2 like bZIP transcription factor 2

increases activity
affects expression

EXP
ISO

cyanidin results in increased activity of NFE2L2 protein
cyanidin affects the expression of NFE2L2 protein

PMID:26505893 PMID:27166148

NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090

G

nitric oxide synthase 3

increases expression

ISO

cyanidin results in increased expression of NOS3 mRNA

NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664

G

proliferating cell nuclear antigen

multiple interactions

ISO

cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of PCNA protein]

NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901

G

platelet derived growth factor subunit A

multiple interactions

ISO

cyanidin inhibits the reaction [[PDGFA protein binds to PDGFB protein] which results in increased abundance of Reactive Oxygen Species]; cyanidin inhibits the reaction [[PDGFA protein binds to PDGFB protein] which results in increased secretion of VEGFA protein]

NCBI chr12:20,759,366...20,780,337
Ensembl chr12:20,754,208...20,780,322

G

platelet derived growth factor subunit B

multiple interactions

ISO

cyanidin inhibits the reaction [[PDGFA protein binds to PDGFB protein] which results in increased abundance of Reactive Oxygen Species]; cyanidin inhibits the reaction [[PDGFA protein binds to PDGFB protein] which results in increased secretion of VEGFA protein]

NCBI chr 7:113,419,882...113,438,343
Ensembl chr 7:113,420,710...113,438,343

G

protein inhibitor of activated STAT, 3

multiple interactions

ISO

[cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of and results in increased phosphorylation of STAT3 protein]] which results in increased expression of PIAS3 protein

NCBI chr 2:186,921,384...186,930,292
Ensembl chr 2:186,921,428...186,936,714

G

signal transducer and activator of transcription 3

multiple interactions

ISO
EXP

[cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of and results in increased phosphorylation of STAT3 protein]] which results in increased expression of PIAS3 protein; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of and results in increased phosphorylation of STAT3 protein]
cyanidin inhibits the reaction [Freund's Adjuvant results in increased phosphorylation of STAT3 protein]

NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359

G

toll-like receptor 3

multiple interactions

ISO
EXP

cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of TLR3 protein]; cyanidin inhibits the reaction [IL17A protein promotes the reaction [Freund's Adjuvant results in increased expression of TLR3 protein]]
cyanidin inhibits the reaction [Freund's Adjuvant results in increased expression of TLR3 protein]

NCBI chr16:53,554,916...53,572,321
Ensembl chr16:53,555,131...53,568,385

G

tumor necrosis factor

multiple interactions

ISO

cyanidin inhibits the reaction [Benzo(a)pyrene results in increased expression of TNF mRNA]

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303

G

uncoupling protein 2

multiple interactions

ISO

cyanidin inhibits the reaction [Benzo(a)pyrene results in increased expression of UCP2 mRNA]

NCBI chr 1:164,251,373...164,257,742
Ensembl chr 1:164,251,373...164,257,743

G

vascular endothelial growth factor A

multiple interactions

ISO

cyanidin inhibits the reaction [[PDGFA protein binds to PDGFB protein] which results in increased secretion of VEGFA protein]; cyanidin inhibits the reaction [cobaltous chloride results in increased expression of VEGFA mRNA]

PMID:16921400 PMID:26800359

NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194

G

Wnt inhibitory factor 1

multiple interactions

EXP

cyanidin inhibits the reaction [bisphenol A results in increased expression of WIF1 mRNA]

NCBI chr 7:58,433,326...58,503,853
Ensembl chr 7:58,384,643...58,503,852

G

Wnt family member 3A

multiple interactions

EXP

cyanidin inhibits the reaction [bisphenol A results in decreased expression of WNT3A mRNA]

NCBI chr10:44,533,734...44,577,919
Ensembl chr10:44,533,734...44,577,919

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	20871
role	20829
chemical role	20408
antioxidant	16458
cyanidin cation	30
6-hydroxycyanidin	0
cyanidin 3,3',5-tri-O-glucoside	0
cyanidin 3,7-di-O-beta-D-glucoside	0
cyanidin 3,7-di-O-beta-D-glucoside betaine	0
cyanidin 3-O-(2''-O-galloyl-beta-D-galactopyranoside)	0
cyanidin 3-O-(2-O-beta-D-glucuronosyl)-beta-D-glucoside	0
cyanidin 3-O-(2-O-beta-D-glucuronosyl)-beta-D-glucoside betaine	0
cyanidin 3-O-(2-O-beta-D-glucuronosyl)-beta-D-glucoside(2-)	0
cyanidin 3-O-(6-O-(E)-4-coumaroyl-beta-D-glucoside)	0
cyanidin 3-O-(6-O-acetyl-beta-D-glucoside)	0
cyanidin 3-O-(6-O-glucosyl-2-O-xylosylgalactoside)	0
cyanidin 3-O-(6-O-malonyl-beta-D-glucoside)	0
cyanidin 3-O-[6-O-(4-O-beta-D-glucosyl-p-coumaroyl)-2-O-(2-O-sinapoyl-beta-D-xylosyl)-beta-D-glucosyl]-5-O-(6-O-malonyl-beta-D-glucoside)	0
cyanidin 3-O-[6-O-(4-O-beta-D-glucosyl-p-coumaroyl)-2-O-(beta-D-xylosyl)-beta-D-glucosyl]-5-O-(6-O-malonyl-beta-D-glucoside)	0
cyanidin 3-O-[beta-D-xylosyl-(1->2)-beta-D-galactoside]	0
cyanidin 3-O-[beta-D-xylosyl-(1->2)-beta-D-galactoside](1-)	0
cyanidin 3-O-\	0
cyanidin 3-O-\	0
cyanidin 3-O-beta-D-galactoside +	0
cyanidin 3-O-beta-D-galactoside betaine	0
cyanidin 3-O-beta-D-glucoside	0
cyanidin 3-O-beta-D-glucoside(1-)	0
cyanidin 3-O-beta-D-sambubioside	0
cyanidin 3-O-rutinoside +	0
cyanidin 3-O-rutinoside 5-O-beta-D-glucoside	0
cyanin +	0
cyanin betaine	0
Path 2
Term	Annotations
CHEBI ontology	20871
subatomic particle	20869
composite particle	20869
hadron	20869
baryon	20869
nucleon	20869
atomic nucleus	20869
atom	20869
main group element atom	20792
p-block element atom	20792
carbon group element atom	20725
carbon atom	20721
organic molecular entity	20721
organic molecule	20665
organic cyclic compound	20414
organic heterocyclic compound	19392
oxacycle	18295
benzopyran	12179
1-benzopyran	11911
chromenes	4452
chromene	155
2H-chromene	155
chromenyliums	155
chromenylium	155
flavylium	155
anthocyanidin cation	155
5-hydroxyanthocyanidin	111
cyanidin cation	30
6-hydroxycyanidin	0
cyanidin 3,3',5-tri-O-glucoside	0
cyanidin 3,7-di-O-beta-D-glucoside	0
cyanidin 3,7-di-O-beta-D-glucoside betaine	0
cyanidin 3-O-(2''-O-galloyl-beta-D-galactopyranoside)	0
cyanidin 3-O-(2-O-beta-D-glucuronosyl)-beta-D-glucoside	0
cyanidin 3-O-(2-O-beta-D-glucuronosyl)-beta-D-glucoside betaine	0
cyanidin 3-O-(2-O-beta-D-glucuronosyl)-beta-D-glucoside(2-)	0
cyanidin 3-O-(6-O-(E)-4-coumaroyl-beta-D-glucoside)	0
cyanidin 3-O-(6-O-acetyl-beta-D-glucoside)	0
cyanidin 3-O-(6-O-glucosyl-2-O-xylosylgalactoside)	0
cyanidin 3-O-(6-O-malonyl-beta-D-glucoside)	0
cyanidin 3-O-[6-O-(4-O-beta-D-glucosyl-p-coumaroyl)-2-O-(2-O-sinapoyl-beta-D-xylosyl)-beta-D-glucosyl]-5-O-(6-O-malonyl-beta-D-glucoside)	0
cyanidin 3-O-[6-O-(4-O-beta-D-glucosyl-p-coumaroyl)-2-O-(beta-D-xylosyl)-beta-D-glucosyl]-5-O-(6-O-malonyl-beta-D-glucoside)	0
cyanidin 3-O-[beta-D-xylosyl-(1->2)-beta-D-galactoside]	0
cyanidin 3-O-[beta-D-xylosyl-(1->2)-beta-D-galactoside](1-)	0
cyanidin 3-O-\	0
cyanidin 3-O-\	0
cyanidin 3-O-beta-D-galactoside +	0
cyanidin 3-O-beta-D-galactoside betaine	0
cyanidin 3-O-beta-D-glucoside	0
cyanidin 3-O-beta-D-glucoside(1-)	0
cyanidin 3-O-beta-D-sambubioside	0
cyanidin 3-O-rutinoside +	0
cyanidin 3-O-rutinoside 5-O-beta-D-glucoside	0
cyanin +	0
cyanin betaine	0

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