CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: Se-methyl-L-selenocysteine
Accession: CHEBI:27812
browse the term
Definition: An L-alpha-amino acid compound having methylselanylmethyl as the side-chain.
Synonyms: exact_synonym: (2R)-2-amino-3-methylselanylpropanoic acid
related_synonym: Formula=C4H9NO2Se; InChI=1S/C4H9NO2Se/c1-8-2-3(5)4(6)7/h3H,2,5H2,1H3,(H,6,7)/t3-/m0/s1; InChIKey=XDSSPSLGNGIIHP-VKHMYHEASA-N; L-methylselenocysteine; Methylselenocysteine; SMILES=C[Se]C[C@H](N)C(O)=O; Se-Methyl-selenocysteine; Se-methyl-seleno-L-cysteine; Se-methylselenocysteine; Selenium methyl cysteine; Selenium-methylselenocystine; Selenohomocysteine; Selenomethylselenocysteine; methyl-L-selenocysteine
alt_id: CHEBI:22076; CHEBI:9067
xref: Beilstein:2636762; CAS:2574-71-2; CAS:26046-90-2; KEGG:C05689
xref_mesh: MESH:C002979
cyclic_relationship: is_conjugate_acid_of CHEBI:53126; is_conjugate_base_of CHEBI:53130; is_enantiomer_of CHEBI:53125; is_tautomer_of CHEBI:58531
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Abcc1
ATP binding cassette subfamily C member 1
multiple interactions
ISO
[selenomethylselenocysteine co-treated with irinotecan] results in decreased expression of ABCC1
CTD
PMID:15897249
NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
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Abcc4
ATP binding cassette subfamily C member 4
multiple interactions decreases expression
EXP
Isoflavones promotes the reaction [selenomethylselenocysteine results in decreased expression of ABCC4 mRNA]
CTD
PMID:19025659
NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
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Apaf1
apoptotic peptidase activating factor 1
increases expression
ISO
selenomethylselenocysteine metabolite results in increased expression of APAF1 mRNA
CTD
PMID:25321483
NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
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Ar
androgen receptor
decreases expression
ISO EXP
selenomethylselenocysteine results in decreased expression of AR protein selenomethylselenocysteine results in decreased expression of AR mRNA
CTD
PMID:16637076 PMID:19025659
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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Bak1
BCL2-antagonist/killer 1
increases expression
ISO
selenomethylselenocysteine metabolite results in increased expression of BAK1 mRNA
CTD
PMID:25321483
NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
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Banp
Btg3 associated nuclear protein
increases expression
ISO
selenomethylselenocysteine results in increased expression of BANP mRNA
CTD
PMID:18514395
NCBI chr19:50,007,710...50,082,742
Ensembl chr19:50,007,881...50,082,738
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Bcl2
BCL2, apoptosis regulator
decreases expression multiple interactions
ISO EXP
selenomethylselenocysteine results in decreased expression of BCL2 mRNA [selenomethylselenocysteine results in decreased expression of BCL2 mRNA] which results in increased activity of TNFSF10 protein selenomethylselenocysteine results in decreased expression of BCL2 protein
CTD
PMID:11396176 PMID:19360359
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Bcl2l1
Bcl2-like 1
decreases expression
ISO
selenomethylselenocysteine metabolite results in decreased expression of BCL2L1 mRNA
CTD
PMID:25321483
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 Ensembl chr 1:141,253,523...141,303,479
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Bcl2l11
Bcl2-like 11
increases expression
ISO
selenomethylselenocysteine metabolite results in increased expression of BCL2L11 mRNA
CTD
PMID:25321483
NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
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Bmal1
basic helix-loop-helix ARNT like 1
decreases expression
EXP
selenomethylselenocysteine results in decreased expression of BMAL1 mRNA
CTD
PMID:19122877
NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
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Bmf
Bcl2 modifying factor
multiple interactions increases expression
ISO
4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA]; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP3 protein modified form]; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP6 protein modified form]; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP9 protein modified form]; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of PARP1 protein modified form]; HDAC8 inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA]; selenomethylselenocysteine metabolite inhibits the reaction [HDAC8 protein binds to BMF promoter]; selenomethylselenocysteine metabolite inhibits the reaction [STAT3 protein binds to BMF promoter]; selenomethylselenocysteine metabolite promotes the reaction [EP300 protein binds to BMF promoter]; selenomethylselenocysteine metabolite promotes the reaction [SP3 protein binds to BMF promoter]; STAT3 protein inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA] selenomethylselenocysteine metabolite results in increased expression of BMF mRNA; selenomethylselenocysteine metabolite results in increased expression of BMF protein
CTD
PMID:25321483
NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
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Casp3
caspase 3
increases activity multiple interactions increases expression
ISO
selenomethylselenocysteine results in increased activity of CASP3 protein BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP3 protein modified form]
CTD
PMID:15318939 PMID:25321483
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp6
caspase 6
increases expression multiple interactions
ISO
selenomethylselenocysteine metabolite results in increased expression of CASP6 protein modified form BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP6 protein modified form]
CTD
PMID:25321483
NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
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Casp8
caspase 8
increases expression
ISO
selenomethylselenocysteine metabolite results in increased expression of CASP8 protein modified form
CTD
PMID:25321483
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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Casp9
caspase 9
multiple interactions increases expression
ISO
BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP9 protein modified form]
CTD
PMID:25321483
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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Ccna2
cyclin A2
decreases expression
EXP
selenomethylselenocysteine results in decreased expression of CCNA2 protein
CTD
PMID:11396176
NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
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Ccnd1
cyclin D1
decreases expression multiple interactions
ISO EXP
selenomethylselenocysteine results in decreased expression of CCND1 protein [selenomethylselenocysteine co-treated with Tamoxifen] results in decreased expression of CCND1 protein selenomethylselenocysteine results in decreased expression of CCND1 mRNA; selenomethylselenocysteine results in decreased expression of CCND1 protein
CTD
PMID:11396176 PMID:18855134 PMID:19276161
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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Cdk2
cyclin dependent kinase 2
multiple interactions
ISO
selenomethylselenocysteine results in decreased phosphorylation of and results in decreased activity of CDK2 protein
CTD
PMID:10656618
NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
increases expression multiple interactions
ISO
selenomethylselenocysteine metabolite results in increased expression of CDKN1A protein [Aminooxyacetic Acid results in decreased metabolism of selenomethylselenocysteine] which results in decreased expression of CDKN1A protein
CTD
PMID:25321483
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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Cdkn1b
cyclin-dependent kinase inhibitor 1B
increases expression
EXP
selenomethylselenocysteine results in increased expression of CDKN1B protein
CTD
PMID:11396176 PMID:19276161
NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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Ces1d
carboxylesterase 1D
increases expression
ISO
selenomethylselenocysteine results in increased expression of CES1
CTD
PMID:15897249
NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
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Chmp1a
charged multivesicular body protein 1A
increases expression
ISO
selenomethylselenocysteine results in increased expression of CHMP1A mRNA
CTD
PMID:18514395
NCBI chr19:51,238,153...51,246,433
Ensembl chr19:51,238,160...51,246,436
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Col1a1
collagen type I alpha 1 chain
decreases expression
ISO
selenomethylselenocysteine results in decreased expression of COL1A1 mRNA; selenomethylselenocysteine results in decreased expression of COL1A1 protein
CTD
PMID:18514395
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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Col1a2
collagen type I alpha 2 chain
decreases expression
ISO
selenomethylselenocysteine results in decreased expression of COL1A2 mRNA; selenomethylselenocysteine results in decreased expression of COL1A2 protein
CTD
PMID:18514395
NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
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Col4a5
collagen type IV alpha 5 chain
increases expression
ISO
selenomethylselenocysteine results in increased expression of COL4A5 mRNA
CTD
PMID:18514395
NCBI chr X:105,118,762...105,322,699
Ensembl chr X:105,118,820...105,322,692
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Col6a1
collagen type VI alpha 1 chain
increases expression
ISO
selenomethylselenocysteine results in increased expression of COL6A1 mRNA
CTD
PMID:18514395
NCBI chr20:11,906,105...11,924,599
Ensembl chr20:11,905,957...11,924,597
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Col7a1
collagen type VII alpha 1 chain
decreases expression
ISO
selenomethylselenocysteine results in decreased expression of COL7A1 mRNA
CTD
PMID:18514395
NCBI chr 8:109,604,877...109,637,249
Ensembl chr 8:109,604,861...109,637,252
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Cry2
cryptochrome circadian regulator 2
increases expression
EXP
selenomethylselenocysteine results in increased expression of CRY2 mRNA
CTD
PMID:19122877
NCBI chr 3:78,374,995...78,405,001
Ensembl chr 3:78,374,995...78,404,965
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Cyp3a9
cytochrome P450, family 3, subfamily a, polypeptide 9
multiple interactions
ISO
[selenomethylselenocysteine co-treated with irinotecan] results in increased expression of CYP3A5
CTD
PMID:15897249
NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
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Dbp
D-box binding PAR bZIP transcription factor
increases expression
EXP
selenomethylselenocysteine results in increased expression of DBP mRNA
CTD
PMID:19122877
NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745
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Ddit3
DNA-damage inducible transcript 3
increases expression
ISO
selenomethylselenocysteine results in increased expression of DDIT3 mRNA
CTD
PMID:10656618
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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Dhcr24
24-dehydrocholesterol reductase
decreases expression
EXP
selenomethylselenocysteine results in decreased expression of DHCR24 mRNA
CTD
PMID:19025659
NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137
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Drg1
developmentally regulated GTP binding protein 1
multiple interactions
ISO
[selenomethylselenocysteine co-treated with irinotecan] results in decreased expression of DRG1
CTD
PMID:15897249
NCBI chr14:78,103,876...78,119,976
Ensembl chr14:78,103,876...78,119,953
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Ep300
E1A binding protein p300
multiple interactions
ISO
selenomethylselenocysteine metabolite promotes the reaction [EP300 protein binds to BMF promoter]
CTD
PMID:25321483
NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088 Ensembl chr 7:113,106,247...113,136,088
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Esr1
estrogen receptor 1
decreases expression multiple interactions
ISO
selenomethylselenocysteine results in decreased expression of ESR1 protein [selenomethylselenocysteine co-treated with Tamoxifen] results in decreased expression of ESR1 protein
CTD
PMID:18855134
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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Faslg
Fas ligand
multiple interactions
ISO
[selenomethylselenocysteine co-treated with irinotecan] results in increased expression of FASLG
CTD
PMID:15897249
NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
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Gadd45a
growth arrest and DNA-damage-inducible, alpha
increases expression
ISO
selenomethylselenocysteine results in increased expression of GADD45A mRNA
CTD
PMID:10656618
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
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Gpx1
glutathione peroxidase 1
increases activity increases expression
ISO
selenomethylselenocysteine results in increased activity of GPX1 protein selenomethylselenocysteine results in increased expression of GPX1 mRNA; selenomethylselenocysteine results in increased expression of GPX1 protein
CTD
PMID:18514395 PMID:19033020
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
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Gpx4
glutathione peroxidase 4
increases expression
ISO
selenomethylselenocysteine results in increased expression of GPX4 mRNA
CTD
PMID:18514395
NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
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Grik1
glutamate ionotropic receptor kainate type subunit 1
increases expression
ISO
selenomethylselenocysteine results in increased expression of GRIK1 mRNA
CTD
PMID:18514395
NCBI chr11:27,169,739...27,571,131
Ensembl chr11:27,169,740...27,570,645
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Grik3
glutamate ionotropic receptor kainate type subunit 3
increases expression
ISO
selenomethylselenocysteine results in increased expression of GRIK3 mRNA
CTD
PMID:18514395
NCBI chr 5:137,767,865...137,989,617
Ensembl chr 5:137,767,865...137,984,307
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Hdac8
histone deacetylase 8
multiple interactions
ISO
HDAC8 inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA]; selenomethylselenocysteine metabolite inhibits the reaction [HDAC8 protein binds to BMF promoter]
CTD
PMID:25321483
NCBI chr X:67,385,288...67,593,014
Ensembl chr X:67,385,289...67,592,923
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Igf1r
insulin-like growth factor 1 receptor
increases expression
ISO
selenomethylselenocysteine results in increased expression of IGF1R mRNA
CTD
PMID:18514395
NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777
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Jun
Jun proto-oncogene, AP-1 transcription factor subunit
increases phosphorylation
EXP
selenomethylselenocysteine results in increased phosphorylation of JUN protein
CTD
PMID:19276161
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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Klk1
kallikrein 1
decreases expression
ISO
selenomethylselenocysteine results in decreased expression of KLK3 protein
CTD
PMID:16637076
NCBI chr 1:94,642,644...94,646,760
Ensembl chr 1:94,642,687...94,646,754
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Mki67
marker of proliferation Ki-67
multiple interactions decreases expression
ISO
[selenomethylselenocysteine co-treated with Tamoxifen] results in decreased expression of MKI67 protein selenomethylselenocysteine results in decreased expression of MKI67 protein
CTD
PMID:18855134
NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
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Msrb1
methionine sulfoxide reductase B1
increases expression
ISO
selenomethylselenocysteine results in increased expression of MSRB1 mRNA
CTD
PMID:18514395
NCBI chr10:13,764,883...13,770,609
Ensembl chr10:13,764,883...13,770,609
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Nfkb1
nuclear factor kappa B subunit 1
multiple interactions
ISO
selenomethylselenocysteine inhibits the reaction [Lipopolysaccharides results in increased localization of NFKB1 protein]
CTD
PMID:21213327
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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Nos2
nitric oxide synthase 2
multiple interactions
ISO
selenomethylselenocysteine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; selenomethylselenocysteine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
CTD
PMID:21213327
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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P4ha1
prolyl 4-hydroxylase subunit alpha 1
increases expression
ISO
selenomethylselenocysteine results in increased expression of P4HA1 mRNA
CTD
PMID:18514395
NCBI chr20:27,302,046...27,352,098
Ensembl chr20:27,302,141...27,352,786
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Parp1
poly (ADP-ribose) polymerase 1
multiple interactions increases expression
ISO
[Aminooxyacetic Acid results in decreased metabolism of selenomethylselenocysteine] which results in decreased expression of PARP1 protein modified form; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of PARP1 protein modified form]
CTD
PMID:25321483
NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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Per2
period circadian regulator 2
increases expression
EXP
selenomethylselenocysteine results in increased expression of PER2 mRNA
CTD
PMID:19122877
NCBI chr 9:92,007,289...92,049,551
Ensembl chr 9:92,007,296...92,049,459
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Per3
period circadian regulator 3
increases expression
EXP
selenomethylselenocysteine results in increased expression of PER3 mRNA
CTD
PMID:19122877
NCBI chr 5:161,460,228...161,495,404
Ensembl chr 5:161,459,533...161,495,607
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Pgr
progesterone receptor
decreases expression multiple interactions
ISO
selenomethylselenocysteine results in decreased expression of PGR protein [selenomethylselenocysteine co-treated with Tamoxifen] results in decreased expression of PGR protein
CTD
PMID:18855134
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
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Ppp1r15a
protein phosphatase 1, regulatory subunit 15A
increases expression
ISO
selenomethylselenocysteine results in increased expression of PPP1R15A mRNA
CTD
PMID:10656618
NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
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Prkce
protein kinase C, epsilon
decreases expression
ISO
selenomethylselenocysteine results in decreased expression of PRKCE protein
CTD
PMID:10656618
NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
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Prkcz
protein kinase C, zeta
decreases expression
ISO
selenomethylselenocysteine results in decreased expression of PRKCZ protein
CTD
PMID:10656618
NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367
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Rab3b
RAB3B, member RAS oncogene family
increases expression
ISO
selenomethylselenocysteine results in increased expression of RAB3B mRNA
CTD
PMID:18514395
NCBI chr 5:123,629,562...123,697,410
Ensembl chr 5:123,644,423...123,697,401
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Rab4a
RAB4A, member RAS oncogene family
increases expression
ISO
selenomethylselenocysteine results in increased expression of RAB4A mRNA
CTD
PMID:18514395
NCBI chr19:51,795,613...51,822,706
Ensembl chr19:51,795,613...51,822,703
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Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions
ISO
selenomethylselenocysteine inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein]
CTD
PMID:21213327
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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Scarb1
scavenger receptor class B, member 1
increases expression
ISO
selenomethylselenocysteine results in increased expression of SCARB1 mRNA
CTD
PMID:18514395
NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
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Selenof
selenoprotein F
increases expression
ISO
selenomethylselenocysteine results in increased expression of SELENOF mRNA
CTD
PMID:18514395
NCBI chr 2:233,642,075...233,674,853
Ensembl chr 2:233,641,932...233,674,846
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Selenop
selenoprotein P
increases expression
ISO
selenomethylselenocysteine results in increased expression of SELENOP mRNA
CTD
PMID:18514395
NCBI chr 2:52,498,123...52,508,409
Ensembl chr 2:52,498,339...52,508,852
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Selenow
selenoprotein W
increases expression
ISO
selenomethylselenocysteine results in increased expression of SELENOW mRNA
CTD
PMID:18514395
NCBI chr 1:76,599,441...76,604,514
Ensembl chr 1:76,598,779...76,604,724 Ensembl chr 1:76,598,779...76,604,724
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Slc3a1
solute carrier family 3 member 1
increases uptake
ISO
SLC3A1 protein results in increased uptake of selenomethylselenocysteine
CTD
PMID:18845132
NCBI chr 6:9,608,169...9,641,881
Ensembl chr 6:9,608,178...9,641,907
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Slc6a19
solute carrier family 6 member 19
increases uptake
ISO
SLC6A19 protein results in increased uptake of selenomethylselenocysteine
CTD
PMID:18845132
NCBI chr 1:29,586,191...29,604,964
Ensembl chr 1:29,586,195...29,604,962
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Slc6a20a
solute carrier family 6 member 20a
increases uptake
ISO
SLC6A20B protein results in increased uptake of selenomethylselenocysteine
CTD
PMID:18845132
NCBI chr 8:123,282,325...123,322,609
Ensembl chr 8:123,281,472...123,322,573
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Snap23
synaptosome associated protein 23
decreases expression
ISO
selenomethylselenocysteine results in decreased expression of SNAP23 mRNA
CTD
PMID:18514395
NCBI chr 3:107,514,088...107,546,177
Ensembl chr 3:107,514,131...107,544,320
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Sort1
sortilin 1
increases expression
ISO
selenomethylselenocysteine results in increased expression of SORT1 mRNA
CTD
PMID:18514395
NCBI chr 2:195,924,033...196,002,354
Ensembl chr 2:195,924,099...196,002,354
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Sp3
Sp3 transcription factor
multiple interactions
ISO
selenomethylselenocysteine metabolite promotes the reaction [SP3 protein binds to BMF promoter]
CTD
PMID:25321483
NCBI chr 3:57,811,855...57,857,150
Ensembl chr 3:57,812,075...57,860,342
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Spp1
secreted phosphoprotein 1
decreases expression
ISO
selenomethylselenocysteine results in decreased expression of SPP1 protein
CTD
PMID:15318939
NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
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Srd5a1
steroid 5 alpha-reductase 1
multiple interactions
EXP
[selenomethylselenocysteine co-treated with Isoflavones] results in decreased activity of SRD5A1 protein
CTD
PMID:19025659
NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461
G
Stat3
signal transducer and activator of transcription 3
multiple interactions
ISO
selenomethylselenocysteine metabolite inhibits the reaction [STAT3 protein binds to BMF promoter]; STAT3 protein inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA]
CTD
PMID:25321483
NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
G
Stx3
syntaxin 3
increases expression
ISO
selenomethylselenocysteine results in increased expression of STX3 mRNA
CTD
PMID:18514395
NCBI chr 1:208,617,018...208,686,240
Ensembl chr 1:208,639,115...208,685,805
G
Tnfsf10
TNF superfamily member 10
multiple interactions
ISO
[selenomethylselenocysteine results in decreased expression of BCL2 mRNA] which results in increased activity of TNFSF10 protein
CTD
PMID:19360359
NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
G
Trnau1ap
tRNA selenocysteine 1 associated protein 1
increases expression
ISO
selenomethylselenocysteine results in increased expression of TRNAU1AP mRNA
CTD
PMID:18514395
NCBI chr 5:144,507,044...144,524,142
Ensembl chr 5:144,507,615...144,524,131
G
Xpa
XPA, DNA damage recognition and repair factor
multiple interactions
ISO
selenomethylselenocysteine inhibits the reaction [Zinc binds to XPA protein]
CTD
PMID:15265038
NCBI chr 5:60,431,673...60,475,726
Ensembl chr 5:60,431,673...60,475,726
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