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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:griseofulvin
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Accession:CHEBI:27779 term browser browse the term
Definition:An oxaspiro compound produced by Penicillium griseofulvum. It is used by mouth as an antifungal drug for infections involving the scalp, hair, nails and skin that do not respond to topical treatment.
Synonyms:exact_synonym: (2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione
 related_synonym: Curling factor;   Formula=C17H17ClO6;   Fulcin;   Fulvicin;   Grifulvin;   Grisactin;   Grisovin;   Grysio;   InChI=1S/C17H17ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h6-8H,5H2,1-4H3/t8-,17+/m1/s1;   InChIKey=DDUHZTYCFQRHIY-RBHXEPJQSA-N;   Lamoryl;   Likuden;   Poncyl;   SMILES=COc1cc(OC)c2C(=O)[C@]3(Oc2c1Cl)[C@H](C)CC(=O)C=C3OC;   Spirofulvin;   Sporostatin;   amudane;   griseofulvina;   griseofulvine;   griseofulvinum
 alt_id: CHEBI:24429;   CHEBI:5546
 xref: CAS:126-07-8;   DrugBank:DB00400;   Drug_Central:1331;   KEGG:C06686;   KEGG:D00209;   KNApSAcK:C00002398;   LINCS:LSM-5259;   LIPID_MAPS_instance:LMPK13060001
 xref_mesh: MESH:D006118
 xref: MetaCyc:CPD-17786;   PMID:14407521;   PMID:15078340;   PMID:16922553;   PMID:23111828;   PMID:25476923;   PMID:3277037;   PPDB:1807;   Patent:US3069328;   Patent:US3069329;   Reaxys:95226;   VSDB:1807;   Wikipedia:Griseofulvin


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griseofulvin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO Griseofulvin results in increased expression of ABCB1A mRNA CTD PMID:8707270 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 increases expression ISO Griseofulvin results in increased expression of ABCB4 mRNA CTD PMID:8707270 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202 		JBrowse link
G Ace2 angiotensin converting enzyme 2 decreases expression EXP
ISO		 Griseofulvin results in decreased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Adrb3 adrenoceptor beta 3 decreases expression ISO Griseofulvin results in decreased expression of ADRB3 mRNA CTD PMID:12735108 NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552 		JBrowse link
G Alas1 5'-aminolevulinate synthase 1 affects expression
increases expression
increases activity
multiple interactions		 ISO Griseofulvin affects the expression of ALAS1 mRNA
Griseofulvin results in increased expression of ALAS1 mRNA
Griseofulvin results in increased activity of ALAS1 protein
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Griseofulvin results in increased activity of ALAS1 protein]; [Ascorbic Acid co-treated with 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid] inhibits the reaction [Griseofulvin results in increased activity of ALAS1 protein]; Ascorbic Acid inhibits the reaction [Griseofulvin results in increased activity of ALAS1 protein]; Melatonin inhibits the reaction [Griseofulvin results in increased activity of ALAS1 protein]		 CTD PMID:10215191 PMID:12735108 PMID:15793285 PMID:24523661 NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917 		JBrowse link
G Anxa2 annexin A2 increases expression ISO Griseofulvin results in increased expression of ANXA2 mRNA CTD PMID:12735108 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658 		JBrowse link
G Anxa3 annexin A3 affects expression ISO Griseofulvin affects the expression of ANXA3 mRNA CTD PMID:12735108 NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617 		JBrowse link
G Anxa5 annexin A5 increases expression ISO Griseofulvin results in increased expression of ANXA5 mRNA CTD PMID:12735108 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369 		JBrowse link
G Anxa6 annexin A6 increases expression ISO Griseofulvin results in increased expression of ANXA6 mRNA CTD PMID:12735108 NCBI chr10:39,101,395...39,156,483
Ensembl chr10:39,097,109...39,156,433 		JBrowse link
G Areg amphiregulin increases expression ISO Griseofulvin results in increased expression of AREG protein CTD PMID:19267999 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535 		JBrowse link
G Btc betacellulin increases expression ISO Griseofulvin results in increased expression of BTC protein CTD PMID:19267999 NCBI chr14:16,708,447...16,746,961
Ensembl chr14:16,707,982...16,747,049 		JBrowse link
G Casp3 caspase 3 increases activity
increases cleavage		 ISO Griseofulvin results in increased activity of CASP3 protein
Griseofulvin results in increased cleavage of CASP3 protein		 CTD PMID:23329179 PMID:25412316 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 increases activity ISO Griseofulvin results in increased activity of CASP9 protein CTD PMID:23329179 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cbr1 carbonyl reductase 1 affects expression ISO Griseofulvin affects the expression of CBR1 mRNA CTD PMID:12735108 NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393 		JBrowse link
G Cd14 CD14 molecule affects expression ISO Griseofulvin affects the expression of CD14 mRNA CTD PMID:12735108 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261 		JBrowse link
G Cd24 CD24 molecule affects expression ISO Griseofulvin affects the expression of CD24A mRNA CTD PMID:12735108 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662 		JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression ISO Griseofulvin results in increased expression of COL1A1 mRNA CTD PMID:12735108 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col3a1 collagen type III alpha 1 chain increases expression ISO Griseofulvin results in increased expression of COL3A1 mRNA CTD PMID:12735108 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547 		JBrowse link
G Col4a1 collagen type IV alpha 1 chain affects expression ISO Griseofulvin affects the expression of COL4A1 mRNA CTD PMID:12735108 NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412 		JBrowse link
G Cstb cystatin B increases expression ISO Griseofulvin results in increased expression of CSTB mRNA CTD PMID:12735108 NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects expression
multiple interactions		 ISO Griseofulvin affects the expression of CYP1A2 mRNA
Griseofulvin promotes the reaction [CYP1A2 protein affects the metabolism of Theophylline]		 CTD PMID:9029748 PMID:12735108 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 affects expression ISO Griseofulvin affects the expression of CYP2A4 mRNA CTD PMID:12735108 NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979 		JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 affects expression ISO Griseofulvin affects the expression of CYP2B13 mRNA CTD PMID:12735108 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 affects expression ISO Griseofulvin affects the expression of CYP2B10 mRNA CTD PMID:12735108 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 affects expression ISO Griseofulvin affects the expression of CYP2C29 mRNA CTD PMID:12735108 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression ISO Griseofulvin results in increased expression of CYP3A4 mRNA; Griseofulvin results in increased expression of CYP3A4 protein CTD PMID:18505790 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 decreases expression ISO Griseofulvin results in decreased expression of CYP7B1 mRNA CTD PMID:12735108 NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698 		JBrowse link
G Eln elastin affects expression ISO Griseofulvin affects the expression of ELN mRNA CTD PMID:12735108 NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928 		JBrowse link
G Ereg epiregulin increases expression ISO Griseofulvin results in increased expression of EREG protein CTD PMID:19267999 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G Fabp1 fatty acid binding protein 1 decreases expression ISO Griseofulvin results in decreased expression of FABP1 mRNA CTD PMID:12735108 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788 		JBrowse link
G Fech ferrochelatase decreases activity
multiple interactions
increases expression		 ISO Griseofulvin results in decreased activity of FECH protein
[Griseofulvin results in decreased activity of FECH protein] which results in decreased uptake of Iron; heme arginate inhibits the reaction [[Griseofulvin results in decreased activity of FECH protein] which results in decreased uptake of Iron]
Griseofulvin results in increased expression of FECH mRNA		 CTD PMID:10215191 PMID:15078340 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348 		JBrowse link
G Fstl1 follistatin-like 1 affects expression ISO Griseofulvin affects the expression of FSTL1 mRNA CTD PMID:12735108 NCBI chr11:62,895,391...62,948,581
Ensembl chr11:62,779,783...62,948,677 		JBrowse link
G G0s2 G0/G1switch 2 decreases expression ISO Griseofulvin results in decreased expression of G0S2 mRNA CTD PMID:12735108 NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta affects expression ISO Griseofulvin affects the expression of GADD45B mRNA CTD PMID:12735108 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046 		JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions
increases expression		 ISO Griseofulvin results in increased expression of and results in increased localization of GJA1 protein
Griseofulvin results in increased expression of GJA1 mRNA		 CTD PMID:23329179 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 affects expression ISO Griseofulvin affects the expression of GSTM2 mRNA CTD PMID:12735108 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961 		JBrowse link
G Hmox1 heme oxygenase 1 increases activity
increases expression		 ISO Griseofulvin results in increased activity of HMOX1 protein
Griseofulvin results in increased expression of HMOX1 mRNA; Griseofulvin results in increased expression of HMOX1 protein		 CTD PMID:10215191 PMID:15793285 PMID:16309571 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Ier3 immediate early response 3 affects expression ISO Griseofulvin affects the expression of IER3 mRNA CTD PMID:12735108 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583 		JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression ISO Griseofulvin results in decreased expression of IGF1 mRNA CTD PMID:12735108 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit decreases expression ISO Griseofulvin results in decreased expression of IGFALS mRNA CTD PMID:12735108 NCBI chr10:13,897,468...13,903,920
Ensembl chr10:13,898,395...13,902,677 		JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 affects expression ISO Griseofulvin affects the expression of IGFBP2 mRNA CTD PMID:12735108 NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO Griseofulvin inhibits the reaction [IL1A protein results in increased expression of VCAM1 protein] CTD PMID:11367519 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Inhbc inhibin subunit beta C decreases expression ISO Griseofulvin results in decreased expression of INHBC mRNA CTD PMID:12735108 NCBI chr 7:63,184,141...63,197,630
Ensembl chr 7:63,184,142...63,197,630 		JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 affects expression ISO Griseofulvin affects the expression of IQGAP1 mRNA CTD PMID:12735108 NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755 		JBrowse link
G Itgb2 integrin subunit beta 2 affects expression ISO Griseofulvin affects the expression of ITGB2 mRNA CTD PMID:12735108 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600 		JBrowse link
G Krt18 keratin 18 multiple interactions
increases expression
decreases response to substance		 ISO Griseofulvin promotes the reaction [KRT18 protein binds to KRT18 protein]
Griseofulvin results in increased expression of KRT18 mRNA
KRT18 protein results in decreased susceptibility to Griseofulvin
Griseofulvin results in increased expression of KRT18 mRNA; Griseofulvin results in increased expression of KRT18 protein		 CTD PMID:7504119 PMID:8770877 PMID:10952237 PMID:12388748 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
Ensembl chr10:133,157,475...133,161,166 		JBrowse link
G Krt8 keratin 8 increases expression
increases phosphorylation		 ISO Griseofulvin results in increased expression of KRT8 mRNA; Griseofulvin results in increased expression of KRT8 protein
Griseofulvin results in increased phosphorylation of KRT8 protein		 CTD PMID:7504119 PMID:10952237 PMID:12735108 PMID:20643122 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728 		JBrowse link
G Lamb1 laminin subunit beta 1 decreases expression ISO Griseofulvin results in decreased expression of LAMB1 protein CTD PMID:1573853 NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:47,835,525...47,902,585 		JBrowse link
G Lamb2 laminin subunit beta 2 decreases expression
increases expression		 ISO Griseofulvin results in decreased expression of LAMB2 protein
Griseofulvin results in increased expression of LAMB2 mRNA		 CTD PMID:1573853 NCBI chr 8:109,178,367...109,190,552
Ensembl chr 8:109,178,409...109,190,549 		JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 affects expression ISO Griseofulvin affects the expression of LILRB4 mRNA CTD PMID:12735108 NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660 		JBrowse link
G Lpl lipoprotein lipase affects expression ISO Griseofulvin affects the expression of LPL mRNA CTD PMID:12735108 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249 		JBrowse link
G Ly6d lymphocyte antigen 6 family member D increases expression ISO Griseofulvin results in increased expression of LY6D mRNA CTD PMID:12735108 NCBI chr 7:106,643,225...106,644,733
Ensembl chr 7:106,643,232...106,644,733 		JBrowse link
G Mapt microtubule-associated protein tau increases expression ISO Griseofulvin results in increased expression of MAPT mRNA; Griseofulvin results in increased expression of MAPT mRNA alternative form; Griseofulvin results in increased expression of MAPT protein CTD PMID:10051481 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129 		JBrowse link
G Mt1 metallothionein 1 increases expression ISO Griseofulvin results in increased expression of MT1 mRNA CTD PMID:12735108 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049
Ensembl chr  X:10,826,032...10,827,049 		JBrowse link
G Npdc1 neural proliferation, differentiation and control, 1 affects expression ISO Griseofulvin affects the expression of NPDC1 mRNA CTD PMID:12735108 NCBI chr 3:8,220,446...8,226,446
Ensembl chr 3:8,213,663...8,226,866 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Griseofulvin results in increased expression of NQO1 mRNA CTD PMID:12735108 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO Griseofulvin inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Papss2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 affects expression ISO Griseofulvin affects the expression of PAPSS2 mRNA CTD PMID:12735108 NCBI chr 1:230,454,314...230,539,332
Ensembl chr 1:230,454,426...230,539,331 		JBrowse link
G Pf4 platelet factor 4 affects expression ISO Griseofulvin affects the expression of PF4 mRNA CTD PMID:12735108 NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365 		JBrowse link
G Por cytochrome p450 oxidoreductase affects expression ISO Griseofulvin affects the expression of POR mRNA CTD PMID:12735108 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression ISO Griseofulvin results in decreased expression of PPARA mRNA CTD PMID:9548566 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta increases expression ISO Griseofulvin results in increased expression of PPARD mRNA CTD PMID:9548566 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO Griseofulvin results in increased expression of PPARG mRNA CTD PMID:9548566 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppl periplakin affects expression ISO Griseofulvin affects the expression of PPL mRNA CTD PMID:12735108 NCBI chr10:10,450,919...10,496,575
Ensembl chr10:10,450,919...10,496,575 		JBrowse link
G Rara retinoic acid receptor, alpha increases expression ISO Griseofulvin results in increased expression of RARA mRNA CTD PMID:9548566 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142 		JBrowse link
G Rarb retinoic acid receptor, beta increases expression ISO Griseofulvin results in increased expression of RARB mRNA CTD PMID:9548566 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288 		JBrowse link
G Rarg retinoic acid receptor, gamma increases expression ISO Griseofulvin results in increased expression of RARG mRNA CTD PMID:9548566 NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177 		JBrowse link
G Rxra retinoid X receptor alpha decreases expression ISO Griseofulvin results in decreased expression of RXRA mRNA CTD PMID:9548566 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712 		JBrowse link
G Rxrg retinoid X receptor gamma decreases expression ISO Griseofulvin results in decreased expression of RXRG mRNA CTD PMID:9548566 NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167 		JBrowse link
G S100a6 S100 calcium binding protein A6 increases expression ISO Griseofulvin results in increased expression of S100A6 mRNA CTD PMID:12735108 NCBI chr 2:176,100,619...176,102,181
Ensembl chr 2:176,100,899...176,102,180 		JBrowse link
G Scd2 stearoyl-Coenzyme A desaturase 2 affects expression ISO Griseofulvin affects the expression of SCD2 mRNA CTD PMID:12735108 NCBI chr 1:243,169,171...243,182,231
Ensembl chr 1:243,169,236...243,182,232 		JBrowse link
G Sele selectin E multiple interactions ISO Griseofulvin inhibits the reaction [TNF protein results in increased expression of SELE protein] CTD PMID:11367519 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741 		JBrowse link
G Sell selectin L decreases expression ISO Griseofulvin results in decreased expression of SELL protein CTD PMID:11367519 NCBI chr13:76,416,969...76,436,444
Ensembl chr13:76,416,915...76,436,456 		JBrowse link
G Soat1 sterol O-acyltransferase 1 affects expression ISO Griseofulvin affects the expression of SOAT1 mRNA CTD PMID:12735108 NCBI chr13:68,552,274...68,597,529
Ensembl chr13:68,552,317...68,597,494 		JBrowse link
G Spp1 secreted phosphoprotein 1 affects expression ISO Griseofulvin affects the expression of SPP1 mRNA CTD PMID:12735108 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Tgm2 transglutaminase 2 affects expression ISO Griseofulvin affects the expression of TGM2 mRNA CTD PMID:12735108 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981 		JBrowse link
G Tm4sf4 transmembrane 4 L six family member 4 affects expression ISO Griseofulvin affects the expression of TM4SF4 mRNA CTD PMID:12735108 NCBI chr 2:141,570,321...141,621,263
Ensembl chr 2:141,481,902...141,621,200 		JBrowse link
G Tmsb10 thymosin, beta 10 affects expression ISO Griseofulvin affects the expression of TMSB10 mRNA CTD PMID:12735108 NCBI chr 4:105,009,959...105,011,095
Ensembl chr 4:105,009,212...105,011,028 		JBrowse link
G Tmsb4x thymosin beta 4, X-linked affects expression ISO Griseofulvin affects the expression of TMSB4X mRNA CTD PMID:12735108 NCBI chr  X:27,144,666...27,146,667
Ensembl chr  X:27,128,610...27,146,667
Ensembl chr10:27,128,610...27,146,667 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Griseofulvin inhibits the reaction [TNF protein results in increased expression of SELE protein]; Griseofulvin inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; Griseofulvin inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; Paclitaxel inhibits the reaction [Griseofulvin inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]]; Paclitaxel inhibits the reaction [Griseofulvin inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]] CTD PMID:11154858 PMID:11367519 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase affects expression ISO Griseofulvin affects the expression of UGDH mRNA CTD PMID:12735108 NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 affects expression ISO Griseofulvin affects the expression of UGT1A1 mRNA CTD PMID:12735108 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 affects expression
multiple interactions		 ISO Griseofulvin affects the expression of VCAM1 mRNA
Griseofulvin inhibits the reaction [IL1A protein results in increased expression of VCAM1 protein]; Griseofulvin inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; Griseofulvin inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; Paclitaxel inhibits the reaction [Griseofulvin inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]]; Paclitaxel inhibits the reaction [Griseofulvin inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]]		 CTD PMID:11154858 PMID:11367519 PMID:12735108 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958 		JBrowse link
G Vcl vinculin affects localization ISO Griseofulvin affects the localization of VCL protein CTD PMID:25412316 NCBI chr15:3,265,776...3,355,586
Ensembl chr15:3,265,815...3,355,606 		JBrowse link
G Wnt3a Wnt family member 3A affects expression ISO Griseofulvin affects the expression of WNT3A mRNA CTD PMID:12735108 NCBI chr10:44,034,174...44,078,366
Ensembl chr10:44,034,194...44,078,324 		JBrowse link
G Ybx3 Y box binding protein 3 affects expression ISO Griseofulvin affects the expression of YBX3 mRNA CTD PMID:12735108 NCBI chr 4:165,129,747...165,153,101
Ensembl chr 4:165,129,758...165,153,161 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    role 19850
      biological role 19848
        antimicrobial agent 18250
          antibacterial agent 16369
            griseofulvin 86
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      carbon group element atom 19757
                        carbon atom 19754
                          organic molecular entity 19754
                            organic molecule 19706
                              organic cyclic compound 19495
                                organic heterocyclic compound 18874
                                  oxacycle 17906
                                    benzofurans 3287
                                      1-benzofurans 1427
                                        griseofulvin 86
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