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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:vincaleukoblastine
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Accession:CHEBI:27375 term browser browse the term
Definition:A vinca alkaloid that has formula C46H58N4O9.
Synonyms:related_synonym: (2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE;   Formula=C46H58N4O9;   InChI=1S/C46H58N4O9/c1-8-42(54)23-28-24-45(40(52)57-6,36-30(15-19-49(25-28)26-42)29-13-10-11-14-33(29)47-36)32-21-31-34(22-35(32)56-5)48(4)38-44(31)17-20-50-18-12-16-43(9-2,37(44)50)39(59-27(3)51)46(38,55)41(53)58-7/h10-14,16,21-22,28,37-39,47,54-55H,8-9,15,17-20,23-26H2,1-7H3/t28-,37+,38-,39-,42+,43-,44-,45+,46+/m1/s1;   InChIKey=JXLYSJRDGCGARV-XQKSVPLYSA-N;   SMILES=[H][C@@]12N3CC[C@@]11c4cc(c(OC)cc4N(C)[C@@]1([H])[C@](O)([C@H](OC(C)=O)[C@]2(CC)C=CC3)C(=O)OC)[C@]1(C[C@@H]2CN(CCc3c1[nH]c1ccccc31)C[C@](O)(CC)C2)C(=O)OC;   VLB;   Vinblastine;   vinblastina;   vinblastinum
 alt_id: CHEBI:27287;   CHEBI:46447;   CHEBI:9983
 xref: Beilstein:4779207;   CAS:865-21-4;   DrugBank:DB00570;   Drug_Central:2823;   HMDB:HMDB0014710;   KEGG:C07201;   KEGG:D08675;   KNApSAcK:C00001781
 xref_mesh: MESH:D014747
 xref: PDBeChem:VLB;   PMID:11878966;   PMID:15917812;   PMID:20394103;   PMID:22868758;   PMID:25586069;   PMID:26660762;   PMID:27518442;   PMID:35404502;   Wikipedia:Vinblastine


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vincaleukoblastine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 decreases response to substance
increases expression		 ISO ABCA2 mRNA results in decreased susceptibility to Vinblastine
Vinblastine results in increased expression of ABCA2 mRNA		 CTD PMID:16928819 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537 		JBrowse link
G Abca3 ATP binding cassette subfamily A member 3 decreases response to substance
increases expression		 ISO ABCA3 mRNA results in decreased susceptibility to Vinblastine
Vinblastine results in increased expression of ABCA3 mRNA		 CTD PMID:16928819 NCBI chr10:13,382,439...13,439,748
Ensembl chr10:13,382,540...13,439,745 		JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 decreases uptake
decreases activity
multiple interactions
increases export		 ISO ABCB11 protein results in decreased uptake of Vinblastine
Vinblastine results in decreased activity of ABCB11 protein
Vinblastine inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
ABCB11 protein results in increased export of Vinblastine		 CTD PMID:10617675 PMID:24014644 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A decreases response to substance
increases secretion
increases activity
increases expression
affects binding
multiple interactions
affects uptake
increases transport		 ISO
EXP		 ABCB1 protein results in decreased susceptibility to Vinblastine
ABCB1A protein results in increased secretion of Vinblastine
Vinblastine results in increased activity of ABCB1 protein mutant form
Vinblastine results in increased expression of ABCB1 protein
Vinblastine binds to ABCB1 protein
[Carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Vinblastine]] which results in decreased susceptibility to Vinblastine; [Elacridar binds to and results in decreased activity of ABCB1 protein] which results in decreased export of Vinblastine; [Glycyrrhetinic Acid affects the activity of ABCB1 protein] which affects the susceptibility to Vinblastine; [sodium arsenite results in increased expression of ABCB1 protein] which results in decreased susceptibility to Vinblastine; [Vinblastine results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA; Amiodarone inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; Carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Vinblastine]; Clotrimazole inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; cnidiadin inhibits the reaction [ABCB1 protein results in increased export of Vinblastine]; Curcumin analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vinblastine]; Curcumin inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vinblastine]; Cyclosporine inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; Diazinon affects the reaction [ABCB1 protein results in increased transport of Vinblastine]; Erythromycin inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; Ketoconazole inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; Miconazole inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; NR1I2 protein promotes the reaction [Vinblastine results in increased expression of ABCB1 protein]; Reserpine inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; Sesquiterpenes analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vinblastine]; Troleandomycin inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; Verapamil inhibits the reaction [ABCB1 protein affects the uptake of Vinblastine]; Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Vinblastine]; Vinblastine inhibits the reaction [Verapamil analog results in increased activity of ABCB1 protein mutant form]		 CTD PMID:1967174 PMID:8917702 PMID:9148857 PMID:11355955 PMID:11455017 More... NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B increases secretion EXP ABCB1B protein results in increased secretion of Vinblastine CTD PMID:12235267 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 affects response to substance
decreases response to substance		 ISO
EXP		 ABCC1 protein affects the susceptibility to Vinblastine
ABCC1 protein results in decreased susceptibility to Vinblastine		 CTD PMID:9334814 PMID:11455017 PMID:16156793 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 affects transport
decreases response to substance
multiple interactions		 ISO
EXP		 ABCC2 protein affects the transport of Vinblastine
ABCC2 protein results in decreased susceptibility to Vinblastine
[isopropyl 5,12-hydroxypentadeca-8,10-dien-6,14-diynoate results in decreased activity of ABCC2 protein] which results in increased uptake of Vinblastine; [verlukast results in decreased activity of ABCC2 protein] which results in increased uptake of Vinblastine; Probenecid promotes the reaction [ABCC2 protein affects the transport of Vinblastine]		 CTD PMID:9525973 PMID:11455017 PMID:15849751 PMID:25844889 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Ablim1 actin-binding LIM protein 1 affects response to substance ISO ABLIM1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:256,083,747...256,372,075
Ensembl chr 1:256,084,297...256,371,969 		JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 affects response to substance ISO ACAT2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821 		JBrowse link
G Acot13 acyl-CoA thioesterase 13 affects response to substance ISO ACOT13 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr17:40,240,378...40,252,851
Ensembl chr17:40,240,378...40,252,851 		JBrowse link
G Acp1 acid phosphatase 1 affects response to substance ISO ACP1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:47,506,380...47,522,021
Ensembl chr 6:47,506,380...47,522,021 		JBrowse link
G Add3 adducin 3 affects response to substance ISO ADD3 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:252,147,341...252,255,126
Ensembl chr 1:252,147,386...252,255,124 		JBrowse link
G Aif1 allograft inflammatory factor 1 decreases expression EXP Vinblastine results in decreased expression of AIF1 mRNA CTD PMID:20624997 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668 		JBrowse link
G Ak1 adenylate kinase 1 decreases expression EXP Vinblastine results in decreased expression of AK1 mRNA CTD PMID:20624997 NCBI chr 3:15,912,431...15,923,045
Ensembl chr 3:15,912,485...15,923,041 		JBrowse link
G Aox1 aldehyde oxidase 1 affects response to substance ISO AOX1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770 		JBrowse link
G Apln apelin decreases expression EXP Vinblastine results in decreased expression of APLN mRNA CTD PMID:20624997 NCBI chr  X:127,180,801...127,213,567
Ensembl chr  X:127,203,823...127,213,391 		JBrowse link
G Atp5me ATP synthase membrane subunit e affects response to substance ISO ATP5ME protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr14:1,319,868...1,320,996
Ensembl chr14:1,319,868...1,321,013 		JBrowse link
G Atp5mf ATP synthase membrane subunit f affects response to substance ISO ATP5MF protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr12:9,421,665...9,428,236
Ensembl chr12:9,421,579...9,428,236 		JBrowse link
G Aurkb aurora kinase B affects response to substance ISO AURKB protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837 		JBrowse link
G Axl Axl receptor tyrosine kinase affects response to substance ISO AXL protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265 		JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 affects response to substance ISO BIRC2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 affects response to substance ISO BIRC3 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G Birc7 baculoviral IAP repeat-containing 7 decreases response to substance ISO BIRC7 protein results in decreased susceptibility to Vinblastine CTD PMID:17437058 NCBI chr 3:168,047,824...168,052,606
Ensembl chr 3:168,047,824...168,052,606 		JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase affects response to substance ISO BUB1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650 		JBrowse link
G C10h5orf15 similar to human chromosome 5 open reading frame 15 affects response to substance ISO C5ORF15 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr10:36,563,989...36,576,593
Ensembl chr10:36,563,958...36,576,590 		JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions		 EXP
ISO		 Vinblastine results in increased cleavage of CASP3 protein
CD40LG protein inhibits the reaction [Vinblastine promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]; Vinblastine promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]		 CTD PMID:16545138 PMID:20624997 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cat catalase affects response to substance ISO CAT protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression EXP Vinblastine results in increased expression of CCL2 mRNA CTD PMID:20624997 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccn2 cellular communication network factor 2 affects response to substance ISO CCN2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Ccnb1 cyclin B1 affects response to substance
increases response to substance		 ISO CCNB1 protein affects the susceptibility to Vinblastine
CCNB1 protein results in increased susceptibility to Vinblastine		 CTD PMID:16217747 PMID:16849574 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccnb2 cyclin B2 affects response to substance ISO CCNB2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874 		JBrowse link
G Cd14 CD14 molecule increases expression EXP Vinblastine results in increased expression of CD14 mRNA CTD PMID:20624997 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261 		JBrowse link
G Cd40lg CD40 ligand decreases response to substance
multiple interactions		 ISO CD40LG protein results in decreased susceptibility to Vinblastine
CD40LG protein inhibits the reaction [Vinblastine promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]		 CTD PMID:16545138 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306 		JBrowse link
G Cd44 CD44 molecule increases expression EXP Vinblastine results in increased expression of CD44 mRNA CTD PMID:20624997 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cdca8 cell division cycle associated 8 affects response to substance ISO CDCA8 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 affects response to substance ISO CDK1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Cdk2 cyclin dependent kinase 2 affects response to substance ISO CDK2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP Vinblastine results in increased expression of CDKN1A mRNA CTD PMID:20624997 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C affects response to substance ISO CDKN2C protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278 		JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression EXP Vinblastine results in decreased expression of CDKN3 mRNA CTD PMID:20624997 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945 		JBrowse link
G Cenpa centromere protein A affects response to substance ISO CENPA protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675 		JBrowse link
G Ckap2 cytoskeleton associated protein 2 affects response to substance ISO CKAP2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913 		JBrowse link
G Cox17 cytochrome c oxidase copper chaperone COX17 affects response to substance ISO COX17 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr11:62,400,733...62,406,507 JBrowse link
G Cox5a cytochrome c oxidase subunit 5A affects response to substance ISO COX5A protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:57,922,374...57,933,781
Ensembl chr 8:57,922,290...57,933,781 		JBrowse link
G Cox6b1 cytochrome c oxidase subunit 6B1 affects response to substance ISO COX6B1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:85,875,080...85,884,081
Ensembl chr 1:85,875,109...85,884,001
Ensembl chr 2:85,875,109...85,884,001 		JBrowse link
G Cp ceruloplasmin increases expression EXP Vinblastine results in increased expression of CP mRNA CTD PMID:20624997 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075 		JBrowse link
G Creg1 cellular repressor of E1A-stimulated genes 1 affects response to substance ISO CREG1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr13:78,019,814...78,032,310
Ensembl chr13:78,019,843...78,032,308 		JBrowse link
G Cript CXXC repeat containing interactor of PDZ3 domain affects response to substance ISO CRIPT protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:7,581,428...7,589,384
Ensembl chr 6:7,580,703...7,589,399 		JBrowse link
G Ctss cathepsin S increases expression EXP Vinblastine results in increased expression of CTSS mRNA CTD PMID:20624997 NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO Vinblastine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] CTD PMID:11602686 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Dcps decapping enzyme, scavenger affects response to substance ISO DCPS protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:33,468,669...33,524,407
Ensembl chr 8:33,415,671...33,524,389 		JBrowse link
G Ddx23 DEAD-box helicase 23 affects response to substance ISO DDX23 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:129,797,620...129,814,909
Ensembl chr 7:129,797,614...129,814,949 		JBrowse link
G Dera deoxyribose-phosphate aldolase affects response to substance ISO DERA protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 4:170,663,689...170,742,469
Ensembl chr 4:170,663,665...170,758,865 		JBrowse link
G Dffb DNA fragmentation factor subunit beta affects response to substance ISO DFFB protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 5:164,522,446...164,534,733
Ensembl chr 5:164,522,463...164,534,628 		JBrowse link
G Dipk1a divergent protein kinase domain 1A affects response to substance ISO DIPK1A protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr14:1,772,412...1,843,508
Ensembl chr14:1,772,422...1,843,743 		JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 affects response to substance ISO DKK1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202 		JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 affects response to substance ISO DKK3 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:166,237,969...166,281,271
Ensembl chr 1:166,238,238...166,280,590 		JBrowse link
G Donson DNA replication fork stabilization factor DONSON affects response to substance ISO DONSON protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr11:30,919,834...30,933,150
Ensembl chr11:30,923,239...30,932,889 		JBrowse link
G Dscc1 DNA replication and sister chromatid cohesion 1 affects response to substance ISO DSCC1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:86,482,588...86,498,212
Ensembl chr 7:86,482,588...86,498,212 		JBrowse link
G E2f1 E2F transcription factor 1 increases response to substance ISO E2F1 protein results in increased susceptibility to Vinblastine CTD PMID:16849574 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361 		JBrowse link
G Ednrb endothelin receptor type B increases expression EXP Vinblastine results in increased expression of EDNRB mRNA CTD PMID:20624997 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
G Efcab7 EF-hand calcium binding domain 7 affects response to substance ISO EFCAB7 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 5:114,525,403...114,576,130
Ensembl chr 5:114,525,167...114,576,129 		JBrowse link
G Emp2 epithelial membrane protein 2 affects response to substance ISO EMP2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr10:5,360,073...5,394,734
Ensembl chr10:5,360,073...5,394,733 		JBrowse link
G Epcam epithelial cell adhesion molecule affects response to substance ISO EPCAM protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127 		JBrowse link
G Eprs1 glutamyl-prolyl-tRNA synthetase 1 increases expression EXP Vinblastine results in increased expression of EPRS1 mRNA CTD PMID:20624997 NCBI chr13:96,901,548...96,971,966
Ensembl chr13:96,901,575...96,971,966 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 affects response to substance ISO ERBB2 protein affects the susceptibility to Vinblastine CTD PMID:10327070 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Ereg epiregulin affects response to substance ISO EREG protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G Esm1 endothelial cell-specific molecule 1 decreases expression EXP Vinblastine results in decreased expression of ESM1 mRNA CTD PMID:20624997 NCBI chr 2:44,876,067...44,884,805
Ensembl chr 2:44,876,067...44,884,804 		JBrowse link
G Etfb electron transfer flavoprotein subunit beta affects response to substance ISO ETFB protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:93,851,908...93,866,072
Ensembl chr 1:93,851,858...93,866,068 		JBrowse link
G Exosc9 exosome component 9 affects response to substance ISO EXOSC9 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:119,416,028...119,426,981
Ensembl chr 2:119,388,715...119,427,051 		JBrowse link
G F3 coagulation factor III, tissue factor increases expression EXP Vinblastine results in increased expression of F3 mRNA CTD PMID:20624997 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G Fam3c FAM3 metabolism regulating signaling molecule C affects response to substance ISO FAM3C protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 4:50,839,929...50,887,276
Ensembl chr 4:50,838,818...50,888,078 		JBrowse link
G Fancl FA complementation group L affects response to substance ISO FANCL protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr14:100,249,733...100,317,958
Ensembl chr14:100,248,875...100,314,255 		JBrowse link
G Faslg Fas ligand increases expression ISO Vinblastine results in increased expression of FASLG protein CTD PMID:11716366 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fcgr2b Fc gamma receptor 2B increases expression EXP Vinblastine results in increased expression of FCGR2B mRNA CTD PMID:20624997 NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778 		JBrowse link
G Fen1 flap structure-specific endonuclease 1 affects response to substance ISO FEN1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003 		JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A affects response to substance ISO FKBP1A protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743 		JBrowse link
G Fli1 Fli-1 proto-oncogene, ETS transcription factor affects response to substance ISO FLI1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:30,831,422...30,950,468
Ensembl chr 8:30,832,753...30,950,433 		JBrowse link
G Fn1 fibronectin 1 affects response to substance ISO FN1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit affects response to substance ISO FOSL1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930 		JBrowse link
G G0s2 G0/G1switch 2 affects response to substance ISO G0S2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression EXP Vinblastine results in increased expression of GADD45A mRNA CTD PMID:20624997 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta increases expression EXP Vinblastine results in increased expression of GADD45B mRNA CTD PMID:20624997 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046 		JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma increases expression EXP Vinblastine results in increased expression of GADD45G mRNA CTD PMID:20624997 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610 		JBrowse link
G Gas7 growth arrest specific 7 decreases expression EXP Vinblastine results in decreased expression of GAS7 mRNA CTD PMID:20624997 NCBI chr10:52,152,718...52,383,283
Ensembl chr10:52,152,493...52,383,276 		JBrowse link
G Ggct gamma-glutamyl cyclotransferase affects response to substance ISO GGCT protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 4:84,122,921...84,129,327
Ensembl chr 4:84,123,118...84,129,277 		JBrowse link
G Ggcx gamma-glutamyl carboxylase affects response to substance ISO GGCX protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 4:104,469,737...104,485,631
Ensembl chr 4:104,469,765...104,487,063 		JBrowse link
G Gmnn geminin, DNA replication inhibitor affects response to substance ISO GMNN protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr17:40,301,771...40,310,054
Ensembl chr17:40,301,808...40,310,054 		JBrowse link
G Gnptab N-acetylglucosamine-1-phosphate transferase subunits alpha and beta affects response to substance ISO GNPTAB protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:22,800,502...22,866,336
Ensembl chr 7:22,800,485...22,866,933 		JBrowse link
G Gpr176 G protein-coupled receptor 176 affects response to substance ISO GPR176 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 3:105,236,794...105,337,664
Ensembl chr 3:105,236,795...105,337,226 		JBrowse link
G Gpsm2 G-protein signaling modulator 2 affects response to substance ISO GPSM2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:196,327,149...196,375,322
Ensembl chr 2:196,327,149...196,375,154 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases response to substance EXP GSTP1 protein results in decreased susceptibility to Vinblastine CTD PMID:11455017 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Gtf2i general transcription factor II I affects response to substance ISO GTF2I protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr12:22,400,933...22,476,243
Ensembl chr12:22,401,431...22,476,243 		JBrowse link
G Gtf3a general transcription factor III A affects response to substance ISO GTF3A protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr12:8,136,746...8,144,690
Ensembl chr12:8,136,747...8,144,690 		JBrowse link
G Gtse1 G-2 and S-phase expressed 1 affects response to substance ISO GTSE1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:116,949,997...116,966,826
Ensembl chr 7:116,950,053...116,966,806 		JBrowse link
G Gusb glucuronidase, beta affects response to substance ISO GUSB protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr12:26,701,188...26,714,718
Ensembl chr12:26,697,951...26,726,905 		JBrowse link
G H1f2 H1.2 linker histone, cluster member affects response to substance ISO H1-2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr17:41,391,106...41,392,597
Ensembl chr17:41,388,477...41,392,635 		JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase affects response to substance ISO HADH protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353 		JBrowse link
G Hcls1 hematopoietic cell specific Lyn substrate 1 affects response to substance ISO HCLS1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr11:63,817,482...63,840,943
Ensembl chr11:63,817,476...63,841,014 		JBrowse link
G Hmgb1 high mobility group box 1 affects response to substance ISO HMGB1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hmgb2 high mobility group box 2 affects response to substance ISO HMGB2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140 		JBrowse link
G Hmgn3 high mobility group nucleosomal binding domain 3 affects response to substance ISO HMGN3 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:84,022,493...84,059,329
Ensembl chr 8:84,022,495...84,062,976 		JBrowse link
G Hmmr hyaluronan-mediated motility receptor affects response to substance ISO HMMR protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP Vinblastine results in increased expression of HMOX1 mRNA CTD PMID:20624997 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Homer1 homer scaffold protein 1 affects response to substance ISO HOMER1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785 		JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression
decreases expression		 EXP
ISO		 Vinblastine results in increased expression of ICAM1 mRNA
Vinblastine results in decreased expression of ICAM1 mRNA; Vinblastine results in decreased expression of ICAM1 protein		 CTD PMID:12649748 PMID:20624997 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Id2 inhibitor of DNA binding 2 affects response to substance ISO ID2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 affects response to substance ISO IDH2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025 		JBrowse link
G Igf2bp3 insulin-like growth factor 2 mRNA binding protein 3 affects response to substance ISO IGF2BP3 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 4:78,060,494...78,195,007
Ensembl chr 4:78,060,494...78,194,865 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta increases phosphorylation
multiple interactions		 ISO Vinblastine results in increased phosphorylation of IKBKB protein
Vinblastine results in decreased localization of [IKBKB protein binds to NFKBIA protein]		 CTD PMID:17029595 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250 		JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 affects response to substance ISO IL13RA2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr  X:111,002,590...111,074,053
Ensembl chr  X:111,002,592...111,072,381 		JBrowse link
G Il1b interleukin 1 beta affects response to substance
increases expression		 ISO
EXP		 IL1B protein affects the susceptibility to Vinblastine
Vinblastine results in increased expression of IL1B mRNA		 CTD PMID:16217747 PMID:20624997 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 decreases chemical synthesis
increases stability		 ISO Vinblastine results in decreased chemical synthesis of IL6 protein
Vinblastine results in increased stability of IL6 mRNA		 CTD PMID:16499908 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Inha inhibin subunit alpha decreases expression EXP Vinblastine results in decreased expression of INHA mRNA CTD PMID:20624997 NCBI chr 9:76,994,465...76,997,366
Ensembl chr 9:76,993,589...76,997,248 		JBrowse link
G Inhba inhibin subunit beta A affects response to substance ISO INHBA protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982 		JBrowse link
G Itgal integrin subunit alpha L decreases expression ISO Vinblastine results in decreased expression of ITGAL mRNA; Vinblastine results in decreased expression of ITGAL protein CTD PMID:12649748 NCBI chr 1:181,918,183...181,955,735
Ensembl chr 1:181,918,183...181,955,732 		JBrowse link
G Itgb1bp1 integrin subunit beta 1 binding protein 1 affects response to substance ISO ITGB1BP1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:40,820,693...40,836,074
Ensembl chr 6:40,821,339...40,836,037 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases phosphorylation		 ISO TP53 protein affects the reaction [Vinblastine results in increased phosphorylation of JUN protein] CTD PMID:12221076 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kank1 KN motif and ankyrin repeat domains 1 affects response to substance ISO KANK1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:222,877,962...223,074,514
Ensembl chr 1:222,877,622...223,074,514 		JBrowse link
G Kazn kazrin, periplakin interacting protein affects response to substance ISO KAZN protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 5:154,392,793...155,381,567
Ensembl chr 5:154,392,793...154,779,074 		JBrowse link
G Kif11 kinesin family member 11 affects response to substance ISO KIF11 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766 		JBrowse link
G Kif15 kinesin family member 15 affects response to substance ISO KIF15 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:122,601,888...122,672,750
Ensembl chr 8:122,601,897...122,672,750 		JBrowse link
G Kif1b kinesin family member 1B affects response to substance ISO KIF1B protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 5:159,607,697...159,742,778
Ensembl chr 5:159,561,271...159,742,778 		JBrowse link
G Kif20a kinesin family member 20A affects response to substance ISO KIF20A protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780 		JBrowse link
G Kif23 kinesin family member 23 affects response to substance ISO KIF23 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072 		JBrowse link
G Kif4a kinesin family member 4A affects response to substance ISO KIF4A protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr  X:65,721,746...65,824,277
Ensembl chr  X:65,721,779...65,824,139 		JBrowse link
G Kpna2 karyopherin subunit alpha 2 affects response to substance ISO KPNA2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr10:91,933,951...91,946,115
Ensembl chr10:91,933,951...91,946,150 		JBrowse link
G Lmnb1 lamin B1 affects response to substance ISO LMNB1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502 		JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 affects response to substance ISO LPAR1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 5:73,229,047...73,347,874
Ensembl chr 5:73,229,625...73,369,895 		JBrowse link
G Lrrc1 leucine rich repeat containing 1 affects response to substance ISO LRRC1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:78,239,897...78,407,347
Ensembl chr 8:78,239,900...78,406,490 		JBrowse link
G Lsm7 LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated affects response to substance ISO LSM7 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:8,856,698...8,859,113
Ensembl chr 7:8,856,489...8,859,119 		JBrowse link
G Ltbp2 latent transforming growth factor beta binding protein 2 affects response to substance ISO LTBP2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:104,429,947...104,530,498
Ensembl chr 6:104,429,947...104,526,208 		JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 affects response to substance ISO MAD2L1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 4:95,906,692...95,918,885
Ensembl chr 4:95,906,817...95,913,470 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation
multiple interactions		 ISO Vinblastine results in increased phosphorylation of MAPK8 protein
TP53 protein affects the reaction [Vinblastine results in increased phosphorylation of MAPK8 protein]		 CTD PMID:12221076 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions
increases phosphorylation		 ISO TP53 protein affects the reaction [Vinblastine results in increased phosphorylation of MAPK9 protein] CTD PMID:12221076 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Mapkapk5 MAPK activated protein kinase 5 affects response to substance ISO MAPKAPK5 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr12:34,993,520...35,013,059
Ensembl chr12:34,994,092...35,013,052 		JBrowse link
G Melk maternal embryonic leucine zipper kinase affects response to substance ISO MELK protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 5:58,540,393...58,600,562
Ensembl chr 5:58,540,449...58,600,937 		JBrowse link
G Mme membrane metallo-endopeptidase affects response to substance ISO MME protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792 		JBrowse link
G Mmp1 matrix metallopeptidase 1 affects response to substance ISO MMP1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mok MOK protein kinase affects response to substance ISO MOK protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:129,823,794...129,854,669
Ensembl chr 6:129,823,795...129,854,700 		JBrowse link
G Mrpl57 mitochondrial ribosomal protein L57 affects response to substance ISO MRPL57 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr15:31,970,904...31,971,766
Ensembl chr15:31,970,860...31,973,993 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor affects response to substance
increases expression		 ISO
EXP		 MYC protein affects the susceptibility to Vinblastine
Vinblastine results in increased expression of MYC mRNA		 CTD PMID:18802399 PMID:20624997 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Mycbp Myc binding protein affects response to substance ISO MYCBP protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 5:136,135,955...136,143,163
Ensembl chr 5:136,135,931...136,145,616 		JBrowse link
G Nbn nibrin increases expression EXP Vinblastine results in increased expression of NBN mRNA CTD PMID:20624997 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150 		JBrowse link
G Ncapg non-SMC condensin I complex, subunit G affects response to substance ISO NCAPG protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr14:65,403,930...65,432,902
Ensembl chr14:65,404,163...65,432,902 		JBrowse link
G Ncaph non-SMC condensin I complex, subunit H affects response to substance ISO NCAPH protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 3:114,371,937...114,399,178
Ensembl chr 3:114,371,941...114,399,180 		JBrowse link
G Ndc80 NDC80 kinetochore complex component affects response to substance ISO NDC80 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924 		JBrowse link
G Ndufa1 NADH:ubiquinone oxidoreductase subunit A1 affects response to substance ISO NDUFA1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr  X:116,424,223...116,427,875
Ensembl chr  X:116,424,223...116,428,633 		JBrowse link
G Ndufa13 NADH:ubiquinone oxidoreductase subunit A13 affects response to substance ISO NDUFA13 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr16:19,526,633...19,533,567
Ensembl chr16:19,526,565...19,535,726 		JBrowse link
G Ndufa3 NADH:ubiquinone oxidoreductase subunit A3 affects response to substance ISO NDUFA3 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:65,597,567...65,600,197
Ensembl chr 1:65,597,578...65,600,235 		JBrowse link
G Ndufa7 NADH:ubiquinone oxidoreductase subunit A7 affects response to substance ISO NDUFA7 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:14,609,283...14,622,064
Ensembl chr 7:14,609,146...14,631,976 		JBrowse link
G Ndufb2 NADH:ubiquinone oxidoreductase subunit B2 affects response to substance ISO NDUFB2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 4:68,367,526...68,374,609
Ensembl chr15:46,536,062...46,536,851
Ensembl chr 4:46,536,062...46,536,851 		JBrowse link
G Ndufc1 NADH:ubiquinone oxidoreductase subunit C1 affects response to substance ISO NDUFC1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:135,447,067...135,450,950
Ensembl chr 2:135,447,119...135,450,874 		JBrowse link
G Ndufc2 NADH:ubiquinone oxidoreductase subunit C2 affects response to substance ISO NDUFC2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:151,711,965...151,718,188
Ensembl chr 1:151,711,901...151,718,189 		JBrowse link
G Ndufs6 NADH:ubiquinone oxidoreductase subunit S6 affects response to substance ISO NDUFS6 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:29,968,833...29,977,423
Ensembl chr 1:29,968,842...29,977,467 		JBrowse link
G Ndufv2 NADH:ubiquinone oxidoreductase core subunit V2 affects response to substance ISO NDUFV2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 9:105,690,454...105,710,669
Ensembl chr 9:105,690,455...105,710,713 		JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 decreases localization ISO Vinblastine results in decreased localization of NFATC4 protein CTD PMID:17044076 NCBI chr15:29,286,998...29,314,610
Ensembl chr15:29,305,535...29,314,610 		JBrowse link
G Nfkbia NFKB inhibitor alpha increases phosphorylation
multiple interactions		 ISO Vinblastine results in increased phosphorylation of NFKBIA protein
Vinblastine results in decreased localization of [IKBKB protein binds to NFKBIA protein]		 CTD PMID:17029595 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Ngf nerve growth factor decreases response to substance EXP Vinblastine results in decreased susceptibility to NGF protein CTD PMID:9524088 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Npy neuropeptide Y decreases expression EXP Vinblastine results in decreased expression of NPY mRNA CTD PMID:1671012 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO Vinblastine inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity		 ISO [Vinblastine results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA; NR1I2 protein promotes the reaction [Vinblastine results in increased expression of ABCB1 protein] CTD PMID:20041327 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nsmaf neutral sphingomyelinase activation associated factor affects response to substance ISO NSMAF protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 5:19,517,795...19,578,773
Ensembl chr 5:19,518,348...19,577,627 		JBrowse link
G Nudt15 nudix hydrolase 15 affects response to substance ISO NUDT15 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr15:48,707,776...48,713,847
Ensembl chr15:48,709,700...48,747,363 		JBrowse link
G Nudt4 nudix hydrolase 4 affects response to substance ISO NUDT4 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:30,188,100...30,204,615
Ensembl chr 7:30,188,100...30,204,615 		JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 affects response to substance ISO NUSAP1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 3:106,603,273...106,633,428
Ensembl chr 3:106,603,289...106,633,624 		JBrowse link
G Oaz1 ornithine decarboxylase antizyme 1 affects response to substance ISO OAZ1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:8,883,855...8,886,315
Ensembl chr 7:8,883,851...8,886,310 		JBrowse link
G Odc1 ornithine decarboxylase 1 multiple interactions ISO Vinblastine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein] CTD PMID:9270009 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440 		JBrowse link
G Oip5 Opa interacting protein 5 affects response to substance ISO OIP5 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 3:106,593,746...106,603,281
Ensembl chr 3:106,593,760...106,603,250 		JBrowse link
G Or1i2 olfactory receptor family 1 subfamily I member 2 affects response to substance ISO OR1I1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:10,985,938...10,986,879
Ensembl chr 7:10,980,344...10,987,036 		JBrowse link
G Orc6 origin recognition complex, subunit 6 affects response to substance ISO ORC6 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr19:21,757,867...21,765,638
Ensembl chr19:21,757,866...21,765,662 		JBrowse link
G Osbpl10 oxysterol binding protein-like 10 affects response to substance ISO OSBPL10 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:114,661,050...114,918,664
Ensembl chr 8:114,660,743...114,918,625 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO CD40LG protein inhibits the reaction [Vinblastine promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]; Vinblastine promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein] CTD PMID:16545138 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pdhb pyruvate dehydrogenase E1 subunit beta affects response to substance ISO PDHB protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr15:16,752,561...16,758,503
Ensembl chr15:16,750,980...16,758,500 		JBrowse link
G Pelo pelota mRNA surveillance and ribosome rescue factor affects response to substance ISO PELO protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:46,797,853...46,799,621
Ensembl chr 2:46,797,853...46,799,746 		JBrowse link
G Pgrmc1 progesterone receptor membrane component 1 affects response to substance ISO PGRMC1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr  X:115,832,865...115,841,060
Ensembl chr  X:115,832,884...115,888,682 		JBrowse link
G Pir pirin affects response to substance ISO PIR protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr  X:30,108,536...30,219,269
Ensembl chr  X:30,108,538...30,219,218 		JBrowse link
G Plagl1 PLAG1 like zinc finger 1 increases expression EXP Vinblastine results in increased expression of PLAGL1 mRNA CTD PMID:20624997 NCBI chr 1:7,477,295...7,517,229
Ensembl chr 1:7,477,177...7,517,228 		JBrowse link
G Plat plasminogen activator, tissue type increases expression EXP Vinblastine results in increased expression of PLAT mRNA CTD PMID:20624997 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223 		JBrowse link
G Plau plasminogen activator, urokinase affects response to substance ISO PLAU protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Plaur plasminogen activator, urokinase receptor increases expression EXP Vinblastine results in increased expression of PLAUR mRNA CTD PMID:20624997 NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression EXP Vinblastine results in increased expression of PPP1R15A mRNA CTD PMID:20624997 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171 		JBrowse link
G Prc1 protein regulator of cytokinesis 1 affects response to substance ISO PRC1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765 		JBrowse link
G Prkcd protein kinase C, delta affects localization ISO Vinblastine affects the localization of PRKCD protein CTD PMID:9852137 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Psmb1 proteasome 20S subunit beta 1 affects response to substance ISO PSMB1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:56,442,432...56,463,544
Ensembl chr 1:56,420,618...56,463,560 		JBrowse link
G Psme4 proteasome activator subunit 4 affects response to substance ISO PSME4 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr14:104,505,716...104,609,410
Ensembl chr14:104,505,716...104,609,408 		JBrowse link
G Ptges3 prostaglandin E synthase 3 affects response to substance ISO PTGES3 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084 		JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin affects response to substance ISO PTTG1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837 		JBrowse link
G Ptx3 pentraxin 3 affects response to substance ISO PTX3 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323 		JBrowse link
G Qrich1 glutamine-rich 1 increases phosphorylation ISO Vinblastine results in increased phosphorylation of QRICH1 protein CTD PMID:17510977 NCBI chr 8:109,216,900...109,256,472
Ensembl chr 8:109,217,376...109,261,359 		JBrowse link
G Rab11fip1 RAB11 family interacting protein 1 affects response to substance ISO RAB11FIP1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr16:64,886,902...64,917,491
Ensembl chr16:64,884,676...64,917,491 		JBrowse link
G Racgap1 Rac GTPase-activating protein 1 affects response to substance ISO RACGAP1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:130,750,936...130,780,891
Ensembl chr 7:130,750,936...130,780,831 		JBrowse link
G Ranbp1 RAN binding protein 1 affects response to substance ISO RANBP1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr11:82,742,603...82,750,836
Ensembl chr11:82,742,600...82,750,838 		JBrowse link
G Rassf1 Ras association domain family member 1 increases expression EXP Vinblastine results in increased expression of RASSF1 mRNA CTD PMID:20624997 NCBI chr 8:108,225,023...108,236,164
Ensembl chr 8:108,225,023...108,236,164 		JBrowse link
G Rev3l REV3 like, DNA directed polymerase zeta catalytic subunit affects response to substance ISO REV3L protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr20:43,131,841...43,290,102
Ensembl chr20:43,132,363...43,290,099 		JBrowse link
G Rfc5 replication factor C subunit 5 affects response to substance ISO RFC5 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr12:39,207,484...39,217,041
Ensembl chr12:39,207,484...39,217,312 		JBrowse link
G Rpa3 replication protein A3 affects response to substance ISO RPA3 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 4:36,304,649...36,307,755
Ensembl chr 4:36,304,651...36,307,709 		JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 affects response to substance ISO RRM2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773 		JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression EXP Vinblastine results in increased expression of S100A8 mRNA CTD PMID:20624997 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643 		JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression EXP Vinblastine results in increased expression of S100A9 mRNA CTD PMID:20624997 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G Sele selectin E increases expression EXP Vinblastine results in increased expression of SELE mRNA CTD PMID:20624997 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741 		JBrowse link
G Serpinb2 serpin family B member 2 affects response to substance ISO SERPINB2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408 		JBrowse link
G Serpine1 serpin family E member 1 increases expression
affects response to substance		 EXP
ISO		 Vinblastine results in increased expression of SERPINE1 mRNA
SERPINE1 protein affects the susceptibility to Vinblastine		 CTD PMID:16217747 PMID:20624997 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Sfxn1 sideroflexin 1 affects response to substance ISO SFXN1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr17:10,486,250...10,522,640
Ensembl chr17:10,486,271...10,522,529 		JBrowse link
G Shtn1 shootin 1 affects response to substance ISO SHTN1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:258,121,966...258,225,861
Ensembl chr 1:258,121,968...258,228,265 		JBrowse link
G Skic8 SKI8 subunit of superkiller complex affects response to substance ISO SKIC8 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:55,103,542...55,120,837
Ensembl chr 8:55,103,545...55,120,813 		JBrowse link
G Skp2 S-phase kinase associated protein 2 affects response to substance ISO SKP2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338 		JBrowse link
G Slc22a3 solute carrier family 22 member 3 affects response to substance ISO SLC22A3 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612 		JBrowse link
G Snrnp25 small nuclear ribonucleoprotein U11/U12 subunit 25 affects response to substance ISO SNRNP25 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr10:15,420,482...15,423,806
Ensembl chr10:15,420,486...15,423,804 		JBrowse link
G Snx10 sorting nexin 10 affects response to substance ISO SNX10 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 4:80,612,648...80,677,005
Ensembl chr 4:80,612,669...80,676,996 		JBrowse link
G Sod1 superoxide dismutase 1 affects response to substance ISO SOD1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression		 ISO bisindolylmaleimide I inhibits the reaction [Vinblastine results in increased expression of SOD2 mRNA]; calphostin C inhibits the reaction [Vinblastine results in increased expression of SOD2 mRNA]; Cycloheximide promotes the reaction [Vinblastine results in increased expression of SOD2 mRNA]; Dactinomycin inhibits the reaction [Vinblastine results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Vinblastine results in increased expression of SOD2 mRNA] CTD PMID:9852137 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sort1 sortilin 1 affects response to substance ISO SORT1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:195,924,033...196,002,354
Ensembl chr 2:195,924,099...196,002,354 		JBrowse link
G Spon1 spondin 1 increases expression EXP Vinblastine results in increased expression of SPON1 mRNA CTD PMID:20624997 NCBI chr 1:167,929,049...168,228,239
Ensembl chr 1:167,928,972...168,228,226 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 affects response to substance ISO SRD5A1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461 		JBrowse link
G Srgn serglycin affects response to substance ISO SRGN protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr20:30,442,810...30,479,549
Ensembl chr20:30,442,813...30,457,406 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO Vinblastine deficiency results in decreased activity of and affects the localization of STAT1 protein CTD PMID:28086195 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO Vinblastine deficiency results in decreased activity of and affects the localization of STAT3 protein CTD PMID:28086195 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Stc2 stanniocalcin 2 affects response to substance ISO STC2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr10:16,251,046...16,260,815
Ensembl chr10:16,250,853...16,262,973 		JBrowse link
G Stk26 serine/threonine kinase 26 affects response to substance ISO STK26 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr  X:130,325,064...130,375,674
Ensembl chr  X:130,310,885...130,374,291 		JBrowse link
G Strn striatin affects response to substance ISO STRN protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:16,335,265...16,422,159
Ensembl chr 6:16,335,358...16,417,083 		JBrowse link
G Sucla2 succinate-CoA ligase ADP-forming subunit beta affects response to substance ISO SUCLA2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr15:48,752,356...48,805,495
Ensembl chr15:48,752,312...48,805,138 		JBrowse link
G Suclg1 succinate-CoA ligase GDP/ADP-forming subunit alpha affects response to substance ISO SUCLG1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 4:105,308,236...105,337,595
Ensembl chr 4:105,308,039...105,337,600 		JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 affects response to substance ISO SULT1A1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562 		JBrowse link
G Syde1 synapse defective Rho GTPase homolog 1 affects response to substance ISO SYDE1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:11,032,931...11,038,917
Ensembl chr 7:11,032,898...11,039,869 		JBrowse link
G Tbc1d4 TBC1 domain family, member 4 affects response to substance ISO TBC1D4 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr15:78,256,030...78,434,168
Ensembl chr15:78,257,121...78,434,265 		JBrowse link
G Tdg thymine-DNA glycosylase affects response to substance ISO TDG protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:21,077,853...21,097,617
Ensembl chr 7:21,077,853...21,097,567 		JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 affects response to substance
increases expression		 ISO
EXP		 TFPI2 protein affects the susceptibility to Vinblastine
Vinblastine results in increased expression of TFPI2 mRNA		 CTD PMID:16217747 PMID:20624997 NCBI chr 4:31,981,786...31,986,707
Ensembl chr 4:31,982,178...31,986,600 		JBrowse link
G Thbd thrombomodulin increases expression EXP Vinblastine results in increased expression of THBD mRNA CTD PMID:20624997 NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193 		JBrowse link
G Thbs1 thrombospondin 1 increases expression EXP Vinblastine results in increased expression of THBS1 mRNA CTD PMID:20624997 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression EXP Vinblastine results in increased expression of TIMP1 mRNA CTD PMID:20624997 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Tmem134 transmembrane protein 134 affects response to substance ISO TMEM134 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:201,419,225...201,424,778
Ensembl chr 1:201,419,264...201,431,411 		JBrowse link
G Tmem14a transmembrane protein 14A affects response to substance ISO TMEM14A protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 9:23,640,594...23,652,379
Ensembl chr 9:23,733,039...23,734,463
Ensembl chr 9:23,733,039...23,734,463 		JBrowse link
G Tmem156 transmembrane protein 156 affects response to substance ISO TMEM156 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr14:43,221,464...43,252,453
Ensembl chr14:43,223,381...43,252,449 		JBrowse link
G Tmem97 transmembrane protein 97 affects response to substance ISO TMEM97 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr10:63,438,228...63,447,311
Ensembl chr10:63,438,222...63,589,730 		JBrowse link
G Tmpo thymopoietin affects response to substance ISO TMPO protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:25,642,752...25,667,756
Ensembl chr 7:25,586,725...25,667,727 		JBrowse link
G Top2a DNA topoisomerase II alpha affects response to substance ISO TOP2A protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO TP53 protein affects the reaction [Vinblastine results in increased phosphorylation of JUN protein]; TP53 protein affects the reaction [Vinblastine results in increased phosphorylation of MAPK8 protein]; TP53 protein affects the reaction [Vinblastine results in increased phosphorylation of MAPK9 protein] CTD PMID:12221076 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tpd52l1 TPD52 like 1 increases expression
affects response to substance		 EXP
ISO		 Vinblastine results in increased expression of TPD52L1 mRNA
TPD52L1 protein affects the susceptibility to Vinblastine		 CTD PMID:16217747 PMID:20624997 NCBI chr 1:26,172,038...26,290,704
Ensembl chr 1:26,172,170...26,291,109 		JBrowse link
G Trim2 tripartite motif-containing 2 affects response to substance ISO TRIM2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:169,500,628...169,652,855
Ensembl chr 2:169,500,634...169,652,927 		JBrowse link
G Trmt5 tRNA methyltransferase 5 affects response to substance ISO TRMT5 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:91,963,558...91,987,660
Ensembl chr 6:91,943,724...91,987,555 		JBrowse link
G Tspan13 tetraspanin 13 affects response to substance ISO TSPAN13 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:52,738,748...52,765,503
Ensembl chr 6:52,738,758...52,765,547 		JBrowse link
G Ttf2 transcription termination factor 2 affects response to substance ISO TTF2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:188,366,321...188,397,750
Ensembl chr 2:188,366,331...188,397,689 		JBrowse link
G Ttk Ttk protein kinase affects response to substance ISO TTK protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651 		JBrowse link
G Tuba1b tubulin, alpha 1B decreases expression EXP Vinblastine results in decreased expression of TUBA1B mRNA CTD PMID:20624997 NCBI chr 7:130,090,663...130,093,644
Ensembl chr 7:130,081,032...130,196,186 		JBrowse link
G Tuba4a tubulin, alpha 4A decreases expression EXP Vinblastine results in decreased expression of TUBA4A mRNA CTD PMID:20624997 NCBI chr 9:76,709,617...76,714,327
Ensembl chr 9:76,709,614...76,713,918 		JBrowse link
G Tubb4b tubulin, beta 4B class IVb decreases expression EXP Vinblastine results in decreased expression of TUBB4B mRNA CTD PMID:20624997 NCBI chr 3:8,037,838...8,040,294
Ensembl chr 3:8,037,799...8,040,296 		JBrowse link
G Tubb5 tubulin, beta 5 class I decreases expression EXP Vinblastine results in decreased expression of TUBB5 mRNA CTD PMID:20624997 NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940 		JBrowse link
G Tubg1 tubulin, gamma 1 decreases expression EXP Vinblastine results in decreased expression of TUBG1 mRNA CTD PMID:20624997 NCBI chr10:86,052,845...86,059,436
Ensembl chr10:86,052,743...86,059,433 		JBrowse link
G Uqcr10 ubiquinol-cytochrome c reductase, complex III subunit X affects response to substance ISO UQCR10 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr14:79,566,151...79,569,017
Ensembl chr14:79,566,157...79,569,003 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression EXP Vinblastine results in increased expression of VCAM1 mRNA CTD PMID:20624997 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958 		JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression EXP Vinblastine results in decreased expression of VEGFA mRNA CTD PMID:20624997 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vegfc vascular endothelial growth factor C affects response to substance ISO VEGFC protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr16:37,712,251...37,827,845
Ensembl chr16:37,712,262...37,827,848 		JBrowse link
G Vwf von Willebrand factor increases expression EXP Vinblastine results in increased expression of VWF mRNA CTD PMID:20624997 NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539 		JBrowse link
G Wsb2 WD repeat and SOCS box-containing 2 affects response to substance ISO WSB2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr12:39,217,645...39,238,634
Ensembl chr12:39,217,648...39,238,640 		JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta affects response to substance ISO YWHAQ protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:40,935,714...40,966,240
Ensembl chr 6:40,935,949...40,966,273 		JBrowse link
G Zdhhc11 zinc finger, DHHC-type containing 11 affects response to substance ISO ZDHHC11 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:29,296,334...29,327,227
Ensembl chr 1:29,296,334...29,326,898 		JBrowse link
G Zfp36l2 zinc finger protein 36, C3H type-like 2 affects response to substance ISO ZFP36L2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:10,490,032...10,494,073
Ensembl chr 6:10,490,032...10,494,064 		JBrowse link
G Zwint ZW10 interacting kinetochore protein affects response to substance ISO ZWINT protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957 		JBrowse link
vincristine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aamdc adipogenesis associated, Mth938 domain containing increases expression ISO Vincristine results in increased expression of AAMDC mRNA CTD PMID:23649840 NCBI chr 1:151,861,990...151,893,621
Ensembl chr 1:151,845,255...151,892,398 		JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions ISO [Vincristine results in decreased susceptibility to Vincristine] which results in increased expression of ABCA1 mRNA CTD PMID:19944135 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170 		JBrowse link
G Abca12 ATP binding cassette subfamily A member 12 increases expression
multiple interactions		 ISO Vincristine results in increased expression of ABCA12 mRNA
[Vincristine results in decreased susceptibility to Vincristine] which results in increased expression of ABCA12 mRNA		 CTD PMID:19944135 PMID:23649840 NCBI chr 9:72,822,661...72,995,748
Ensembl chr 9:72,823,350...72,996,049 		JBrowse link
G Abca4 ATP binding cassette subfamily A member 4 multiple interactions ISO [Vincristine results in decreased susceptibility to Vincristine] which results in increased expression of ABCA4 mRNA CTD PMID:19944135 NCBI chr 2:210,164,813...210,302,069
Ensembl chr 2:210,164,813...210,302,069 		JBrowse link
G Abca5 ATP binding cassette subfamily A member 5 multiple interactions ISO [Vincristine results in decreased susceptibility to Vincristine] which affects the expression of ABCA5 mRNA CTD PMID:19944135 NCBI chr10:95,240,159...95,309,195
Ensembl chr10:95,240,154...95,308,976 		JBrowse link
G Abca8 ATP binding cassette subfamily A member 8 multiple interactions ISO [Vincristine results in decreased susceptibility to Vincristine] which affects the expression of ABCA8 mRNA CTD PMID:19944135 NCBI chr10:94,917,520...94,991,199
Ensembl chr10:94,917,520...94,990,988 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A affects response to substance
increases expression
multiple interactions
increases transport
decreases uptake
decreases response to substance
affects uptake		 ISO
EXP		 ABCB1 protein affects the susceptibility to Vincristine
Vincristine results in increased expression of ABCB1A mRNA
Vincristine results in increased expression of ABCB1 protein
[Estradiol results in decreased expression of ABCB1 protein] which results in increased uptake of and results in increased susceptibility to Vincristine; [MGMT protein co-treated with ABCB1 protein] results in decreased susceptibility to Vincristine; [Paclitaxel results in increased expression of ABCB1] which results in decreased susceptibility to Vincristine; [Vincristine results in decreased susceptibility to Vincristine] which affects the expression of ABCB1 mRNA; [Vincristine results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA; CEP 33779 inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]; Cyclosporine inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]; Fenofibrate inhibits the reaction [ABCB1 protein results in increased transport of Vincristine]; Flupenthixol analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]; NR1I2 protein promotes the reaction [Vincristine results in increased expression of ABCB1 protein]; pinostrobin inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]; tectochrysin inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]; Verapamil inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]; zosuquidar trihydrochloride inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]
ABCB1 protein results in decreased uptake of Vincristine
ABCB1 protein affects the uptake of Vincristine		 CTD PMID:7905786 PMID:10617675 PMID:11792417 PMID:11934808 PMID:15239124 More... NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B affects uptake EXP ABCB1B protein affects the uptake of Vincristine CTD PMID:11934808 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 multiple interactions ISO [Vincristine results in decreased susceptibility to Vincristine] which affects the expression of ABCB4 mRNA CTD PMID:19944135 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202 		JBrowse link
G Abcb6 ATP binding cassette subfamily B member 6 multiple interactions
decreases response to substance		 ISO [Vincristine results in decreased susceptibility to Vincristine] which affects the expression of ABCB6 mRNA
ABCB6 protein results in decreased susceptibility to Vincristine		 CTD PMID:19944135 PMID:25202056 NCBI chr 9:76,668,554...76,677,263
Ensembl chr 9:76,668,554...76,676,924 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases response to substance
increases expression
multiple interactions
decreases response to substance
affects transport
affects response to substance
affects export		 ISO
EXP		 ABCC1 gene SNP results in increased susceptibility to Vincristine
Vincristine results in increased expression of ABCC1 mRNA
[Genistein results in decreased activity of ABCC1 protein] which results in increased uptake of Vincristine; [Indomethacin results in decreased activity of ABCC1 protein] which results in increased uptake of Vincristine; [Probenecid results in decreased activity of ABCC1 protein] which results in increased uptake of Vincristine; [Sulfinpyrazone results in decreased activity of ABCC1 protein] which results in increased uptake of Vincristine; [verlukast results in decreased activity of ABCC1 protein] which results in increased uptake of Vincristine
ABCC1 protein results in decreased susceptibility to Vincristine; ABCC1 results in decreased susceptibility to Vincristine
[MYCN protein affects the expression of ABCC1 mRNA] which affects the susceptibility to Vincristine; [Vincristine results in decreased susceptibility to Vincristine] which results in increased expression of ABCC1 mRNA; ABCC1 protein affects the export of and results in decreased susceptibility to Vincristine; Buthionine Sulfoximine inhibits the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; Cyclosporine inhibits the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; Doxorubicin inhibits the reaction [ABCC1 protein affects the transport of Vincristine]; GSTP1 protein promotes the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; myricetin inhibits the reaction [ABCC1 protein affects the export of and results in decreased susceptibility to Vincristine]; myricetin inhibits the reaction [ABCC1 protein affects the export of Vincristine]; myricetin inhibits the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; Quercetin promotes the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; Verapamil inhibits the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; verlukast inhibits the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; Vincristine inhibits the reaction [ABCC1 protein affects the transport of fluorexon]; Vincristine inhibits the reaction [Glutathione promotes the reaction [ABCC1 results in increased transport of methylarsine analog]]; zafirlukast inhibits the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]
ABCC1 protein affects the transport of Vincristine; ABCC1 protein mutant form affects the transport of Vincristine
ABCC1 protein affects the susceptibility to Vincristine		 CTD PMID:7954421 PMID:8649356 PMID:8968083 PMID:10348353 PMID:10685512 More... NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Abcc10 ATP binding cassette subfamily C member 10 multiple interactions
decreases response to substance		 ISO Imatinib Mesylate inhibits the reaction [ABCC10 protein results in decreased susceptibility to Vincristine]; nilotinib inhibits the reaction [ABCC10 protein results in decreased susceptibility to Vincristine] CTD PMID:19841739 NCBI chr 9:14,657,242...14,677,178
Ensembl chr 9:14,657,264...14,677,178 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 affects export
multiple interactions
decreases response to substance		 ISO ABCC2 protein affects the export of Vincristine
[Vincristine results in decreased susceptibility to Vincristine] which results in increased expression of ABCC2 mRNA; ABCC2 protein affects the export of and results in decreased susceptibility to Vincristine; myricetin inhibits the reaction [ABCC2 protein affects the export of and results in decreased susceptibility to Vincristine]; myricetin inhibits the reaction [ABCC2 protein affects the export of Vincristine]; myricetin inhibits the reaction [ABCC2 protein results in decreased susceptibility to Vincristine]		 CTD PMID:15896345 PMID:19944135 PMID:22095822 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions ISO [Vincristine results in decreased susceptibility to Vincristine] which results in increased expression of ABCC3 mRNA CTD PMID:19944135 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions ISO [Vincristine results in decreased susceptibility to Vincristine] which results in decreased expression of ABCC4 mRNA CTD PMID:19944135 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283 		JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 multiple interactions ISO [Vincristine results in decreased susceptibility to Vincristine] which affects the expression of ABCC5 mRNA CTD PMID:19944135 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253 		JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 multiple interactions ISO [Vincristine results in decreased susceptibility to Vincristine] which results in decreased expression of ABCC6 mRNA CTD PMID:19944135 NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464 		JBrowse link
G Abcd3 ATP binding cassette subfamily D member 3 multiple interactions ISO [Vincristine results in decreased susceptibility to Vincristine] which results in decreased expression of ABCD3 mRNA CTD PMID:19944135 NCBI chr 2:209,852,087...209,905,763
Ensembl chr 2:209,852,087...209,906,020 		JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 multiple interactions ISO [Vincristine results in decreased susceptibility to Vincristine] which results in decreased expression of ABCG1 mRNA CTD PMID:19944135 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO [Paclitaxel results in decreased expression of ABCG2] which results in decreased susceptibility to Vincristine; [Vincristine results in decreased susceptibility to Vincristine] which results in increased expression of ABCG2 mRNA CTD PMID:19944135 PMID:21833476 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Abcg4 ATP binding cassette subfamily G member 4 multiple interactions ISO [Vincristine results in decreased susceptibility to Vincristine] which results in decreased expression of ABCG4 mRNA CTD PMID:19944135 NCBI chr 8:44,611,187...44,629,818
Ensembl chr 8:44,611,187...44,626,881 		JBrowse link
G Abhd11 abhydrolase domain containing 11 decreases expression ISO Vincristine results in decreased expression of ABHD11 mRNA CTD PMID:23649840 NCBI chr12:21,682,206...21,685,331
Ensembl chr12:21,682,202...21,685,398 		JBrowse link
G Abtb2 ankyrin repeat and BTB domain containing 2 increases expression ISO Vincristine results in increased expression of ABTB2 mRNA CTD PMID:23649840 NCBI chr 3:89,954,726...90,108,549
Ensembl chr 3:89,954,713...90,108,548 		JBrowse link
G Acad9 acyl-CoA dehydrogenase family, member 9 decreases expression ISO Vincristine results in decreased expression of ACAD9 mRNA CTD PMID:23649840 NCBI chr 2:118,943,170...118,966,150
Ensembl chr 2:118,943,174...118,966,547 		JBrowse link
G Ache acetylcholinesterase decreases expression
multiple interactions		 EXP Vincristine results in decreased expression of ACHE protein
xaliproden inhibits the reaction [Vincristine results in decreased expression of ACHE protein]		 CTD PMID:8413926 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Ackr3 atypical chemokine receptor 3 increases expression ISO Vincristine results in increased expression of ACKR3 mRNA CTD PMID:23649840 NCBI chr 9:90,799,682...90,811,246
Ensembl chr 9:90,799,686...90,811,237 		JBrowse link
G Actr2 actin related protein 2 increases expression ISO Vincristine results in increased expression of ACTR2 mRNA CTD PMID:23649840 NCBI chr14:94,296,443...94,333,735
Ensembl chr14:94,296,443...94,340,524 		JBrowse link
G Adat2 adenosine deaminase, tRNA-specific 2 decreases expression ISO Vincristine results in decreased expression of ADAT2 mRNA CTD PMID:23649840 NCBI chr 1:7,954,520...7,975,254
Ensembl chr 1:7,954,631...7,975,251 		JBrowse link
G Adgrf4 adhesion G protein-coupled receptor F4 increases expression ISO Vincristine results in increased expression of ADGRF4 mRNA CTD PMID:23649840 NCBI chr 9:18,272,050...18,303,219
Ensembl chr 9:18,272,050...18,303,217 		JBrowse link
G Adrb1 adrenoceptor beta 1 decreases expression ISO Vincristine results in decreased expression of ADRB1 mRNA CTD PMID:23649840 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
G Adrb2 adrenoceptor beta 2 increases response to substance ISO ADRB2 gene SNP results in increased susceptibility to Vincristine CTD PMID:21245421 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Agbl3 AGBL carboxypeptidase 3 decreases expression ISO Vincristine results in decreased expression of AGBL3 mRNA CTD PMID:23649840 NCBI chr 4:63,448,789...63,535,538
Ensembl chr 4:63,453,940...63,531,188 		JBrowse link
G Ahsa2 activator of HSP90 ATPase homolog 2 decreases expression ISO Vincristine results in decreased expression of AHSA2P mRNA CTD PMID:23649840 NCBI chr14:97,476,304...97,485,725
Ensembl chr14:97,476,817...97,485,657 		JBrowse link
G Aim2 absent in melanoma 2 increases expression ISO Vincristine results in increased expression of AIM2 mRNA CTD PMID:23649840 NCBI chr13:85,865,206...85,906,996
Ensembl chr13:85,866,284...85,906,975 		JBrowse link
G Ak1 adenylate kinase 1 decreases expression EXP Vincristine results in decreased expression of AK1 mRNA CTD PMID:20624997 NCBI chr 3:15,912,431...15,923,045
Ensembl chr 3:15,912,485...15,923,041 		JBrowse link
G Ak3 adenylate kinase 3 decreases expression ISO Vincristine results in decreased expression of AK3 mRNA CTD PMID:23649840 NCBI chr 1:226,737,472...226,764,647
Ensembl chr 1:226,739,318...226,764,625 		JBrowse link
G Akap10 A-kinase anchoring protein 10 increases expression ISO Vincristine results in increased expression of AKAP10 mRNA CTD PMID:23649840 NCBI chr10:46,545,371...46,608,730
Ensembl chr10:46,551,532...46,608,769 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases expression		 ISO
EXP		 Vincristine inhibits the reaction [Doxorubicin results in decreased phosphorylation of AKT1 protein]
Vincristine promotes the reaction [NVP ADW742 inhibits the reaction [IGF1 protein results in increased phosphorylation of AKT1 protein]]
Quercetin inhibits the reaction [Vincristine results in decreased expression of AKT1 mRNA]		 CTD PMID:16740780 PMID:18590705 PMID:33038355 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 decreases expression
multiple interactions		 EXP Vincristine results in decreased expression of AKT2 mRNA
Quercetin inhibits the reaction [Vincristine results in decreased expression of AKT2 mRNA]		 CTD PMID:33038355 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817 		JBrowse link
G Aldoc aldolase, fructose-bisphosphate C decreases expression ISO Vincristine results in decreased expression of ALDOC mRNA CTD PMID:23649840 NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066 		JBrowse link
G Alms1 ALMS1, centrosome and basal body associated protein decreases expression ISO Vincristine results in decreased expression of ALMS1 mRNA CTD PMID:23649840 NCBI chr 4:118,125,581...118,226,005
Ensembl chr 4:118,125,607...118,226,005 		JBrowse link
G Alpk2 alpha-kinase 2 increases expression ISO Vincristine results in increased expression of ALPK2 mRNA CTD PMID:23649840 NCBI chr18:58,775,603...58,906,150
Ensembl chr18:58,775,605...58,906,258 		JBrowse link
G Amh anti-Mullerian hormone decreases secretion ISO Vincristine results in decreased secretion of AMH protein CTD PMID:30657998 NCBI chr 7:8,906,776...8,909,192
Ensembl chr 7:8,906,836...8,909,282 		JBrowse link
G Anapc5 anaphase-promoting complex subunit 5 increases expression ISO Vincristine results in increased expression of ANAPC5 mRNA CTD PMID:23649840 NCBI chr12:33,748,709...33,781,709
Ensembl chr12:33,748,735...33,781,781 		JBrowse link
G Ankdd1a ankyrin repeat and death domain containing 1A decreases expression ISO Vincristine results in decreased expression of ANKDD1A mRNA CTD PMID:23649840 NCBI chr 8:66,017,571...66,043,738
Ensembl chr 8:66,017,773...66,042,651 		JBrowse link
G Ankhd1 ankyrin repeat and KH domain containing 1 increases expression ISO Vincristine results in increased expression of ANKHD1 mRNA CTD PMID:23649840 NCBI chr18:28,161,882...28,260,917
Ensembl chr18:28,162,311...28,268,024 		JBrowse link
G Ankra2 ankyrin repeat family A member 2 increases expression ISO Vincristine results in increased expression of ANKRA2 mRNA CTD PMID:23649840 NCBI chr 2:29,612,867...29,623,748
Ensembl chr 2:29,612,925...29,623,730 		JBrowse link
G Ankrd13c ankyrin repeat domain 13C decreases expression ISO Vincristine results in decreased expression of ANKRD13C mRNA CTD PMID:23649840 NCBI chr 2:247,023,040...247,070,433
Ensembl chr 2:247,022,286...247,070,433 		JBrowse link
G Ankrd33b ankyrin repeat domain 33B increases expression ISO Vincristine results in increased expression of ANKRD33B mRNA CTD PMID:23649840 NCBI chr 2:82,277,604...82,359,420
Ensembl chr 2:82,283,108...82,358,872 		JBrowse link
G Ankrd37 ankyrin repeat domain 37 decreases expression ISO Vincristine results in decreased expression of ANKRD37 mRNA CTD PMID:23649840 NCBI chr16:46,268,933...46,271,971
Ensembl chr16:46,268,443...46,271,963 		JBrowse link
G Anp32e acidic nuclear phosphoprotein 32 family member E decreases expression ISO Vincristine results in decreased expression of ANP32E mRNA CTD PMID:23649840 NCBI chr 2:183,472,600...183,489,057
Ensembl chr 2:183,472,609...183,489,054 		JBrowse link
G Anxa1 annexin A1 increases expression ISO Vincristine results in increased expression of ANXA1 mRNA CTD PMID:23649840 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Anxa2 annexin A2 increases expression ISO Vincristine results in increased expression of ANXA2 mRNA CTD PMID:23649840 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658 		JBrowse link
G Ap1s2 adaptor related protein complex 1 subunit sigma 2 decreases expression ISO Vincristine results in decreased expression of AP1S2 mRNA CTD PMID:23649840 NCBI chr  X:30,572,746...30,598,961
Ensembl chr  X:30,572,751...30,597,262 		JBrowse link
G Apex2 apurinic/apyrimidinic endodeoxyribonuclease 2 decreases expression ISO Vincristine results in decreased expression of APEX2 mRNA CTD PMID:23649840 NCBI chr  X:19,425,684...19,508,459
Ensembl chr  X:19,487,419...19,508,439 		JBrowse link
G Apln apelin decreases expression EXP Vincristine results in decreased expression of APLN mRNA CTD PMID:20624997 NCBI chr  X:127,180,801...127,213,567
Ensembl chr  X:127,203,823...127,213,391 		JBrowse link
G Apod apolipoprotein D increases expression ISO Vincristine results in increased expression of APOD mRNA CTD PMID:23649840 NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305 		JBrowse link
G Apold1 apolipoprotein L domain containing 1 increases expression ISO Vincristine results in increased expression of APOLD1 mRNA CTD PMID:23649840 NCBI chr 4:167,768,437...167,825,706
Ensembl chr 4:167,818,271...167,825,706 		JBrowse link
G Aqp9 aquaporin 9 increases expression ISO Vincristine results in increased expression of AQP9 mRNA CTD PMID:23649840 NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395 		JBrowse link
G Arap2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 decreases expression ISO Vincristine results in decreased expression of ARAP2 mRNA CTD PMID:23649840 NCBI chr14:46,717,657...46,917,326
Ensembl chr14:46,718,760...46,917,154 		JBrowse link
G Arf1 ARF GTPase 1 increases expression ISO Vincristine results in increased expression of ARF1 mRNA CTD PMID:23649840 NCBI chr10:43,997,983...44,014,461
Ensembl chr10:43,997,986...44,014,434 		JBrowse link
G Arhgap15 Rho GTPase activating protein 15 increases expression ISO Vincristine results in increased expression of ARHGAP15 mRNA CTD PMID:23649840 NCBI chr 3:27,989,368...28,592,722
Ensembl chr 3:27,989,633...28,600,265 		JBrowse link
G Arhgap18 Rho GTPase activating protein 18 decreases expression ISO Vincristine results in decreased expression of ARHGAP18 mRNA CTD PMID:23649840 NCBI chr 1:18,403,531...18,637,306
Ensembl chr 1:18,403,537...18,637,256 		JBrowse link
G Arhgap5 Rho GTPase activating protein 5 decreases expression ISO Vincristine results in decreased expression of ARHGAP5 mRNA CTD PMID:23649840 NCBI chr 6:69,975,904...70,039,299
Ensembl chr 6:69,976,214...70,037,660 		JBrowse link
G Arhgef6 Rac/Cdc42 guanine nucleotide exchange factor 6 increases expression ISO Vincristine results in increased expression of ARHGEF6 mRNA CTD PMID:23649840 NCBI chr  X:135,145,447...135,264,636
Ensembl chr  X:135,146,786...135,275,304 		JBrowse link
G Arhgef7 Rho guanine nucleotide exchange factor 7 increases expression ISO Vincristine results in increased expression of ARHGEF7 mRNA CTD PMID:23649840 NCBI chr16:77,671,021...77,782,593
Ensembl chr16:77,671,023...77,782,697 		JBrowse link
G Arid2 AT-rich interaction domain 2 increases expression ISO Vincristine results in increased expression of ARID2 mRNA CTD PMID:23649840 NCBI chr 7:127,447,192...127,565,987
Ensembl chr 7:127,447,278...127,563,512 		JBrowse link
G Arid4b AT-rich interaction domain 4B increases expression ISO Vincristine results in increased expression of ARID4B mRNA CTD PMID:23649840 NCBI chr17:51,138,419...51,262,894
Ensembl chr17:51,138,535...51,262,906 		JBrowse link
G Arl5a ARF like GTPase 5A decreases expression ISO Vincristine results in decreased expression of ARL5A mRNA CTD PMID:23649840 NCBI chr 3:36,878,461...36,903,362
Ensembl chr 3:36,880,712...36,903,211 		JBrowse link
G Arl5b ARF like GTPase 5B increases expression ISO Vincristine results in increased expression of ARL5B mRNA CTD PMID:23649840 NCBI chr17:77,955,864...77,979,895
Ensembl chr17:77,955,818...77,979,854 		JBrowse link
G Arl6ip1 ARL6 interacting reticulophagy regulator 1 decreases expression ISO Vincristine results in decreased expression of ARL6IP1 mRNA CTD PMID:23649840 NCBI chr 1:172,430,475...172,439,990
Ensembl chr 1:172,430,489...172,439,994 		JBrowse link
G Armc8 armadillo repeat containing 8 decreases expression ISO Vincristine results in decreased expression of ARMC8 mRNA CTD PMID:23649840 NCBI chr 8:100,036,946...100,131,544
Ensembl chr 8:100,036,946...100,131,520 		JBrowse link
G Aspm assembly factor for spindle microtubules increases expression ISO Vincristine results in increased expression of ASPM mRNA CTD PMID:17374387 NCBI chr13:51,074,849...51,123,755
Ensembl chr13:51,074,849...51,123,755 		JBrowse link
G Asxl1 ASXL transcriptional regulator 1 increases expression ISO Vincristine results in increased expression of ASXL1 mRNA CTD PMID:23649840 NCBI chr 3:141,814,012...141,881,526
Ensembl chr 3:141,813,433...141,881,538 		JBrowse link
G Atad2 ATPase family, AAA domain containing 2 decreases expression ISO Vincristine results in decreased expression of ATAD2 mRNA CTD PMID:23649840 NCBI chr 7:89,634,123...89,676,738
Ensembl chr 7:89,634,123...89,676,738 		JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Vincristine results in increased expression of ATF3 mRNA CTD PMID:23649840 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atf5 activating transcription factor 5 increases expression ISO Vincristine results in increased expression of ATF5 mRNA CTD PMID:23649840 NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707 		JBrowse link
G Atf6 activating transcription factor 6 multiple interactions
increases expression		 EXP Quercetin inhibits the reaction [Vincristine results in increased expression of ATF6 mRNA] CTD PMID:33038355 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177 		JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 increases expression ISO Vincristine results in increased expression of ATP2B4 mRNA CTD PMID:23649840 NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246 		JBrowse link
G Atp5f1c ATP synthase F1 subunit gamma decreases expression ISO Vincristine results in decreased expression of ATP5F1C mRNA CTD PMID:23649840 NCBI chr17:68,423,927...68,446,169
Ensembl chr17:68,423,909...68,608,367 		JBrowse link
G Atp6v0e1 ATPase H+ transporting V0 subunit e1 increases expression ISO Vincristine results in increased expression of ATP6V0E1 mRNA CTD PMID:23649840 NCBI chr10:16,479,656...16,502,732
Ensembl chr10:16,479,567...16,524,434 		JBrowse link
G Atp7a ATPase copper transporting alpha decreases response to substance ISO ATP7A protein results in decreased susceptibility to Vincristine CTD PMID:17510416 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Atp8a1 ATPase phospholipid transporting 8A1 decreases expression ISO Vincristine results in decreased expression of ATP8A1 mRNA CTD PMID:23649840 NCBI chr14:40,315,013...40,557,572
Ensembl chr14:40,315,049...40,554,611 		JBrowse link
G Aurka aurora kinase A increases response to substance
increases expression		 ISO AURKA gene SNP results in increased susceptibility to Vincristine
Vincristine results in increased expression of AURKA mRNA		 CTD PMID:17374387 PMID:20864405 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390 		JBrowse link
G Aurkb aurora kinase B decreases expression ISO Vincristine results in decreased expression of AURKB mRNA CTD PMID:23649840 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837 		JBrowse link
G Avp arginine vasopressin increases expression ISO Vincristine results in increased expression of AVP protein CTD PMID:4356234 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G B3galt6 Beta-1,3-galactosyltransferase 6 decreases expression ISO Vincristine results in decreased expression of B3GALT6 mRNA CTD PMID:23649840 NCBI chr 5:166,584,202...166,586,338
Ensembl chr 5:166,584,202...166,586,338 		JBrowse link
G B3gnt5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 increases expression ISO Vincristine results in increased expression of B3GNT5 mRNA CTD PMID:23649840 NCBI chr11:81,141,102...81,153,206
Ensembl chr11:81,140,599...81,156,166 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 affects response to substance ISO BAK1 protein affects the susceptibility to Vincristine CTD PMID:22178383 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bambi BMP and activin membrane-bound inhibitor increases expression ISO Vincristine results in increased expression of BAMBI mRNA CTD PMID:23649840 NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060 		JBrowse link
G Bard1 BRCA1 associated RING domain 1 decreases expression ISO Vincristine results in decreased expression of BARD1 mRNA CTD PMID:23649840 NCBI chr 9:72,616,070...72,694,553
Ensembl chr 9:72,623,155...72,694,265 		JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 increases expression ISO Vincristine results in increased expression of BASP1 mRNA CTD PMID:23649840 NCBI chr 2:75,816,130...75,863,801
Ensembl chr 2:75,816,122...75,864,043 		JBrowse link
G Batf basic leucine zipper ATF-like transcription factor increases expression ISO Vincristine results in increased expression of BATF mRNA CTD PMID:23649840 NCBI chr 6:105,353,715...105,376,051
Ensembl chr 6:105,353,715...105,376,051 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
multiple interactions
increases expression
affects response to substance		 ISO
EXP		 Vincristine results in decreased expression of BAX mRNA
KN 93 inhibits the reaction [Vincristine results in increased expression of BAX mRNA]; KN 93 inhibits the reaction [Vincristine results in increased expression of BAX protein]
Vincristine results in increased expression of BAX mRNA; Vincristine results in increased expression of BAX protein
Quercetin inhibits the reaction [Vincristine results in increased expression of BAX mRNA]
BAX protein affects the susceptibility to Vincristine
[Doxorubicin co-treated with Vincristine co-treated with Etoposide co-treated with Mitotane] results in decreased expression of BAX protein; Vincristine results in increased cleavage of and results in increased expression of BAX protein		 CTD PMID:9815696 PMID:15131059 PMID:16001973 PMID:22178383 PMID:33038355 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcat1 branched chain amino acid transaminase 1 increases expression ISO Vincristine results in increased expression of BCAT1 mRNA CTD PMID:23649840 NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases response to substance
multiple interactions
decreases expression
increases phosphorylation		 ISO
EXP		 BCL2 protein results in decreased susceptibility to Vincristine
KN 93 inhibits the reaction [Vincristine results in decreased expression of BCL2 mRNA]; KN 93 inhibits the reaction [Vincristine results in decreased expression of BCL2 protein]
Vincristine results in decreased expression of BCL2 mRNA; Vincristine results in decreased expression of BCL2 protein
Quercetin inhibits the reaction [Vincristine results in decreased expression of BCL2 mRNA]
Vincristine results in increased phosphorylation of BCL2 protein
[Doxorubicin co-treated with Dexamethasone co-treated with Vincristine co-treated with Cytarabine co-treated with Mercaptopurine co-treated with Methotrexate co-treated with Cyclophosphamide co-treated with Enzymes and Coenzymes] results in increased expression of BCL2 protein; [Doxorubicin co-treated with Vincristine co-treated with Etoposide co-treated with Mitotane] results in decreased expression of BCL2 protein; [MIR497 results in decreased expression of BCL2 protein] which results in increased susceptibility to Vincristine; TYMP inhibits the reaction [Vincristine results in increased phosphorylation of BCL2 protein]		 CTD PMID:9815696 PMID:15907805 PMID:20162574 PMID:21182165 PMID:21258880 More... NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2a1 BCL2-related protein A1 increases expression ISO Vincristine results in increased expression of BCL2A1 mRNA CTD PMID:23649840 NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998 		JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression
affects response to substance		 ISO Vincristine results in increased expression of BCL2L1 mRNA
BCL2L1 protein affects the susceptibility to Vincristine		 CTD PMID:22178383 PMID:23649840 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bclaf1 BCL2-associated transcription factor 1 decreases expression ISO Vincristine results in decreased expression of BCLAF1 mRNA CTD PMID:23649840 NCBI chr 1:15,088,436...15,117,666
Ensembl chr 1:15,070,894...15,148,832 		JBrowse link
G Bcor BCL6 co-repressor increases expression ISO Vincristine results in increased expression of BCOR mRNA CTD PMID:23649840 NCBI chr  X:10,609,756...10,729,613
Ensembl chr  X:10,687,732...10,729,613 		JBrowse link
G Bdkrb1 bradykinin receptor B1 multiple interactions EXP [HOE 140, desArg(10)- binds to and results in decreased activity of BDKRB1 protein] which results in decreased susceptibility to Vincristine CTD PMID:17989505 NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747 		JBrowse link
G Bdkrb2 bradykinin receptor B2 multiple interactions EXP [icatibant binds to and results in decreased activity of BDKRB2 protein] which results in decreased susceptibility to Vincristine CTD PMID:17989505 NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497 		JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 increases expression ISO Vincristine results in increased expression of BIRC2 mRNA CTD PMID:23649840 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression ISO Vincristine results in increased expression of BIRC3 mRNA CTD PMID:23649840 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G Blm BLM RecQ like helicase decreases expression ISO Vincristine results in decreased expression of BLM mRNA CTD PMID:23649840 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312 		JBrowse link
G Bmp2 bone morphogenetic protein 2 increases expression ISO Vincristine results in increased expression of BMP2 mRNA CTD PMID:23649840 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bnip3 BCL2 interacting protein 3 decreases expression
multiple interactions		 ISO Vincristine results in decreased expression of BNIP3 mRNA
Vincristine affects the reaction [Valproic Acid affects the localization of BNIP3 protein]		 CTD PMID:23649840 PMID:25446377 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G Bnip3l BCL2 interacting protein 3 like decreases expression ISO Vincristine results in decreased expression of BNIP3L mRNA CTD PMID:23649840 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803 		JBrowse link
G Borcs7 BLOC-1 related complex subunit 7 increases expression ISO Vincristine results in increased expression of BORCS7 mRNA CTD PMID:23649840 NCBI chr 1:245,564,347...245,578,182
Ensembl chr 1:245,564,369...245,579,343 		JBrowse link
G Brip1 BRCA1 interacting DNA helicase 1 decreases expression ISO Vincristine results in decreased expression of BRIP1 mRNA CTD PMID:23649840 NCBI chr10:70,907,266...71,031,502
Ensembl chr10:70,907,371...71,030,324 		JBrowse link
G Brwd1 bromodomain and WD repeat domain containing 1 decreases expression ISO Vincristine results in decreased expression of BRWD1 mRNA CTD PMID:23649840 NCBI chr11:35,286,364...35,378,768
Ensembl chr11:35,288,313...35,378,768 		JBrowse link
G Btg1 BTG anti-proliferation factor 1 increases expression ISO Vincristine results in increased expression of BTG1 mRNA CTD PMID:23649840 NCBI chr 7:31,341,391...31,343,649
Ensembl chr 7:31,341,027...31,343,649 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Vincristine results in increased expression of BTG2 mRNA CTD PMID:23649840 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628 		JBrowse link
G Btg4 BTG anti-proliferation factor 4 increases expression ISO Vincristine results in increased expression of BTG4 mRNA CTD PMID:23649840 NCBI chr 8:51,410,774...51,425,802
Ensembl chr 8:51,422,061...51,425,796 		JBrowse link
G Bub3 BUB3 mitotic checkpoint protein decreases expression ISO Vincristine results in decreased expression of BUB3 mRNA CTD PMID:23649840 NCBI chr 1:186,330,358...186,340,969
Ensembl chr 1:186,327,931...186,395,036 		JBrowse link
G C13h1orf74 similar to human chromosome 1 open reading frame 74 decreases expression ISO Vincristine results in decreased expression of C1ORF74 mRNA CTD PMID:23649840 NCBI chr13:104,692,769...104,695,368
Ensembl chr13:104,692,824...104,695,470 		JBrowse link
G C1galt1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1 decreases expression ISO Vincristine results in decreased expression of C1GALT1 mRNA CTD PMID:23649840 NCBI chr 4:35,930,981...35,966,100
Ensembl chr 4:35,928,104...35,961,831 		JBrowse link
G C7h12orf54 similar to human chromosome 12 open reading frame 54 increases expression ISO Vincristine results in increased expression of C12ORF54 mRNA CTD PMID:23649840 NCBI chr 7:129,529,811...129,548,676 JBrowse link
G C8h15orf39 similar to human chromosome 15 open reading frame 39 decreases expression ISO Vincristine results in decreased expression of C15ORF39 mRNA CTD PMID:23649840 NCBI chr 8:57,646,324...57,655,896
Ensembl chr 8:57,645,756...57,655,941 		JBrowse link
G Cables2 Cdk5 and Abl enzyme substrate 2 decreases expression ISO Vincristine results in decreased expression of CABLES2 mRNA CTD PMID:23649840 NCBI chr 3:167,347,527...167,362,274
Ensembl chr 3:167,347,461...167,362,279 		JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H increases expression
multiple interactions		 ISO Vincristine results in increased expression of CACNA1H mRNA; Vincristine results in increased expression of CACNA1H protein
Ascorbic Acid inhibits the reaction [Vincristine results in increased expression of CACNA1H mRNA]; Ascorbic Acid inhibits the reaction [Vincristine results in increased expression of CACNA1H protein]; KN 62 inhibits the reaction [Vincristine results in increased expression of CACNA1H protein]; KN 93 inhibits the reaction [Vincristine results in increased expression of CACNA1H mRNA]; KN 93 inhibits the reaction [Vincristine results in increased expression of CACNA1H protein]; zinc chloride inhibits the reaction [Vincristine results in increased expression of CACNA1H protein]		 CTD PMID:34286406 NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376 		JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 increases expression ISO Vincristine results in increased expression of CACNB2 mRNA CTD PMID:23649840 NCBI chr17:77,564,630...77,910,000
Ensembl chr17:77,564,460...77,909,106 		JBrowse link
G Cald1 caldesmon 1 increases expression ISO Vincristine results in increased expression of CALD1 mRNA CTD PMID:23649840 NCBI chr 4:63,265,781...63,446,938
Ensembl chr 4:63,265,942...63,446,932 		JBrowse link
G Calm2 calmodulin 2 decreases expression ISO Vincristine results in decreased expression of CALM2 mRNA CTD PMID:23649840 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287 		JBrowse link
G Calu calumenin increases expression ISO Vincristine results in increased expression of CALU mRNA CTD PMID:23649840 NCBI chr 4:57,949,086...57,976,589
Ensembl chr 4:57,948,997...57,976,593 		JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta decreases expression ISO Vincristine results in decreased expression of CAMK2D mRNA CTD PMID:23649840 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178 		JBrowse link
G Camkk1 calcium/calmodulin-dependent protein kinase kinase 1 increases response to substance ISO CAMKK1 gene SNP results in increased susceptibility to Vincristine CTD PMID:21245421 NCBI chr10:57,637,335...57,660,498
Ensembl chr10:57,637,391...57,660,498 		JBrowse link
G Capg capping actin protein, gelsolin like increases expression ISO Vincristine results in increased expression of CAPG mRNA CTD PMID:23649840 NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856 		JBrowse link
G Carhsp1 calcium regulated heat stable protein 1 decreases expression ISO Vincristine results in decreased expression of CARHSP1 mRNA CTD PMID:23649840 NCBI chr10:6,946,036...6,960,556
Ensembl chr10:6,946,959...7,020,019 		JBrowse link
G Casp1 caspase 1 increases expression ISO Vincristine results in increased expression of CASP1 mRNA CTD PMID:23649840 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
increases expression		 EXP
ISO		 Vincristine results in increased cleavage of CASP3 protein
KN 93 inhibits the reaction [Vincristine results in increased cleavage of CASP3 protein]
coenzyme Q10 inhibits the reaction [Vincristine results in increased expression of CASP3 protein]; Quercetin inhibits the reaction [Vincristine results in increased expression of CASP3 mRNA]; Quercetin inhibits the reaction [Vincristine results in increased expression of CASP3 protein]; Sumatriptan inhibits the reaction [Vincristine results in increased expression of CASP3 mRNA]; Sumatriptan inhibits the reaction [Vincristine results in increased expression of CASP3 protein]
Vincristine results in increased expression of CASP3 mRNA; Vincristine results in increased expression of CASP3 protein		 CTD PMID:20624997 PMID:29958920 PMID:33038355 PMID:34286406 PMID:34939713 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp6 caspase 6 increases expression ISO Vincristine results in increased expression of CASP6 mRNA CTD PMID:16001973 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502 		JBrowse link
G Casp8 caspase 8 increases expression
increases response to substance
multiple interactions		 ISO Vincristine results in increased expression of CASP8 mRNA
CASP8 protein results in increased susceptibility to Vincristine
Vincristine results in increased expression of and results in increased cleavage of CASP8 protein		 CTD PMID:16001973 PMID:22010212 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Cat catalase affects response to substance
decreases activity
decreases expression
multiple interactions		 ISO
EXP		 CAT protein affects the susceptibility to Vincristine
Vincristine results in decreased activity of CAT protein
Vincristine results in decreased expression of CAT protein
Quercetin inhibits the reaction [Vincristine results in decreased activity of CAT protein]; tetrahydrocurcumin inhibits the reaction [Vincristine results in decreased expression of CAT protein]; Vincristine inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Vincristine inhibits the reaction [Isoproterenol results in decreased expression of CAT protein]		 CTD PMID:11178967 PMID:24201307 PMID:25537132 PMID:26102012 PMID:36808657 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cbx3 chromobox 3 decreases expression ISO Vincristine results in decreased expression of CBX3 mRNA CTD PMID:23649840 NCBI chr 4:80,545,450...80,559,284
Ensembl chr 4:80,546,010...80,559,283 		JBrowse link
G Cbx5 chromobox 5 decreases expression ISO Vincristine results in decreased expression of CBX5 mRNA CTD PMID:23649840 NCBI chr 7:134,333,165...134,376,102
Ensembl chr 7:134,331,335...134,375,022 		JBrowse link
G Ccar1 cell division cycle and apoptosis regulator 1 decreases expression ISO Vincristine results in decreased expression of CCAR1 mRNA CTD PMID:23649840 NCBI chr20:30,685,916...30,728,531
Ensembl chr20:30,685,916...30,728,526 		JBrowse link
G Ccdc12 coiled-coil domain containing 12 decreases expression ISO Vincristine results in decreased expression of CCDC12 mRNA CTD PMID:23649840 NCBI chr 8:110,635,276...110,686,417
Ensembl chr 8:110,635,710...110,686,417 		JBrowse link
G Ccdc186 coiled-coil domain containing 186 decreases expression ISO Vincristine results in decreased expression of CCDC186 mRNA CTD PMID:23649840 NCBI chr 1:255,831,663...255,871,954
Ensembl chr 1:255,839,595...255,871,935 		JBrowse link
G Ccdc198 coiled-coil domain containing 198 decreases expression ISO Vincristine results in decreased expression of CCDC198 mRNA CTD PMID:23649840 NCBI chr15:22,500,181...22,527,011
Ensembl chr15:22,502,687...22,526,992 		JBrowse link
G Ccdc32 coiled-coil domain containing 32 decreases expression ISO Vincristine results in decreased expression of CCDC32 mRNA CTD PMID:23649840 NCBI chr 3:105,998,429...106,010,985
Ensembl chr 3:105,998,430...106,010,975 		JBrowse link
G Ccdc82 coiled-coil domain containing 82 increases expression ISO Vincristine results in increased expression of CCDC82 mRNA CTD PMID:23649840 NCBI chr 8:10,227,727...10,265,963
Ensembl chr 8:10,228,430...10,265,963 		JBrowse link
G Cchcr1 coiled-coil alpha-helical rod protein 1 decreases expression ISO Vincristine results in decreased expression of CCHCR1 mRNA CTD PMID:23649840 NCBI chr20:3,205,675...3,218,437
Ensembl chr20:3,205,676...3,218,308 		JBrowse link
G Ccl1 C-C motif chemokine ligand 1 increases expression ISO Vincristine results in increased expression of CCL1 mRNA CTD PMID:23649840 NCBI chr10:67,128,331...67,131,109
Ensembl chr10:67,128,331...67,131,159 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO
EXP		 Vincristine results in increased expression of CCL2 mRNA CTD PMID:20624997 PMID:23649840 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression ISO Vincristine results in increased expression of CCL20 mRNA CTD PMID:23649840 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Ccl22 C-C motif chemokine ligand 22 increases expression ISO Vincristine results in increased expression of CCL22 mRNA CTD PMID:23649840 NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression ISO Vincristine results in increased expression of CCL4 mRNA CTD PMID:23649840 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO Vincristine results in increased expression of CCL5 mRNA CTD PMID:23649840 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccn2 cellular communication network factor 2 decreases response to substance ISO CCN2 mRNA results in decreased susceptibility to Vincristine CTD PMID:24154679 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Ccnb1 cyclin B1 affects response to substance
increases expression		 ISO CCNB1 protein affects the susceptibility to Vincristine
Vincristine results in increased expression of CCNB1 mRNA		 CTD PMID:22178383 PMID:23649840 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccnb2 cyclin B2 increases expression ISO Vincristine results in increased expression of CCNB2 mRNA CTD PMID:23649840 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874 		JBrowse link
G Ccne1 cyclin E1 decreases expression ISO Vincristine results in decreased expression of CCNE1 mRNA CTD PMID:23649840 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101 		JBrowse link
G Ccne2 cyclin E2 decreases expression ISO Vincristine results in decreased expression of CCNE2 mRNA CTD PMID:23649840 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632 		JBrowse link
G Ccnl1 cyclin L1 decreases expression ISO Vincristine results in decreased expression of CCNL1 mRNA CTD PMID:23649840 NCBI chr 2:150,184,865...150,199,524
Ensembl chr 2:150,184,798...150,197,368 		JBrowse link
G Cd109 CD109 molecule increases expression ISO Vincristine results in increased expression of CD109 mRNA CTD PMID:23649840 NCBI chr 8:79,454,480...79,569,195
Ensembl chr 8:79,454,480...79,569,194 		JBrowse link
G Cd14 CD14 molecule increases expression EXP Vincristine results in increased expression of CD14 mRNA CTD PMID:20624997 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261 		JBrowse link
G Cd200 Cd200 molecule increases expression ISO Vincristine results in increased expression of CD200 mRNA CTD PMID:23649840 NCBI chr11:55,410,166...55,437,527
Ensembl chr11:55,410,196...55,501,648 		JBrowse link
G Cd274 CD274 molecule increases expression ISO Vincristine results in increased expression of CD274 mRNA CTD PMID:23649840 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Cd36 CD36 molecule increases expression EXP Vincristine results in increased expression of CD36 mRNA CTD PMID:20624997 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cd40 CD40 molecule increases expression ISO Vincristine results in increased expression of CD40 mRNA CTD PMID:23649840 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534 		JBrowse link
G Cd44 CD44 molecule increases expression ISO Vincristine results in increased expression of CD44 mRNA CTD PMID:23649840 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cd48 Cd48 molecule increases expression ISO Vincristine results in increased expression of CD48 mRNA CTD PMID:23649840 NCBI chr13:84,184,884...84,209,144
Ensembl chr13:84,185,532...84,209,142 		JBrowse link
G Cd55 CD55 molecule (Cromer blood group) increases expression ISO Vincristine results in increased expression of CD55 mRNA CTD PMID:23649840 NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831 		JBrowse link
G Cd69 Cd69 molecule increases expression ISO Vincristine results in increased expression of CD69 mRNA CTD PMID:23649840 NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542 		JBrowse link
G Cd80 Cd80 molecule increases expression ISO Vincristine results in increased expression of CD80 mRNA CTD PMID:23649840 NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030 		JBrowse link
G Cd83 CD83 molecule increases expression ISO Vincristine results in increased expression of CD83 mRNA CTD PMID:23649840 NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083 		JBrowse link
G Cd86 CD86 molecule increases expression ISO Vincristine results in increased expression of CD86 mRNA CTD PMID:23649840 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Cdc42ep3 CDC42 effector protein 3 increases expression ISO Vincristine results in increased expression of CDC42EP3 mRNA CTD PMID:23649840 NCBI chr 6:15,710,894...15,731,366
Ensembl chr 6:15,708,730...15,732,721 		JBrowse link
G Cdc42ep4 CDC42 effector protein 4 increases expression ISO Vincristine results in increased expression of CDC42EP4 mRNA CTD PMID:23649840 NCBI chr10:98,772,613...98,797,924
Ensembl chr10:98,772,495...98,797,695 		JBrowse link
G Cdc42se1 CDC42 small effector 1 increases expression ISO Vincristine results in increased expression of CDC42SE1 mRNA CTD PMID:23649840 NCBI chr 2:182,805,691...182,813,520
Ensembl chr 2:182,804,925...182,814,028 		JBrowse link
G Cdc6 cell division cycle 6 decreases expression ISO Vincristine results in decreased expression of CDC6 mRNA CTD PMID:23649840 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011 		JBrowse link
G Cdca3 cell division cycle associated 3 decreases expression ISO Vincristine results in decreased expression of CDCA3 mRNA CTD PMID:23649840 NCBI chr 4:157,634,775...157,638,799
Ensembl chr 4:157,634,928...157,638,799 		JBrowse link
G Cdca7 cell division cycle associated 7 decreases expression ISO Vincristine results in decreased expression of CDCA7 mRNA CTD PMID:23649840 NCBI chr 3:57,322,718...57,333,353
Ensembl chr 3:57,322,708...57,333,353 		JBrowse link
G Cdh1 cadherin 1 increases expression ISO Vincristine results in increased expression of CDH1 mRNA CTD PMID:23649840 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO Vincristine results in decreased expression of CDK1 mRNA CTD PMID:23649840 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Cdk10 cyclin-dependent kinase 10 decreases expression ISO Vincristine results in decreased expression of CDK10 mRNA CTD PMID:23649840 NCBI chr19:51,260,012...51,273,009
Ensembl chr19:51,261,356...51,269,078 		JBrowse link
G Cdk19 cyclin-dependent kinase 19 decreases expression ISO Vincristine results in decreased expression of CDK19 mRNA CTD PMID:23649840 NCBI chr20:43,770,409...43,910,629
Ensembl chr20:43,770,409...43,910,628 		JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO Vincristine results in decreased expression of CDK2 mRNA CTD PMID:23649840 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions		 EXP
ISO		 Vincristine results in increased expression of CDKN1A mRNA
[XL019 compound co-treated with Vincristine] results in increased expression of CDKN1A protein; Resveratrol inhibits the reaction [Vincristine results in increased expression of CDKN1A mRNA]		 CTD PMID:20624997 PMID:23649840 PMID:26055805 PMID:29187454 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases response to substance ISO CDKN2A protein results in increased susceptibility to Vincristine CTD PMID:16786135 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C decreases expression ISO Vincristine results in decreased expression of CDKN2C mRNA CTD PMID:23649840 NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 increases expression ISO Vincristine results in increased expression of CEACAM1 mRNA CTD PMID:23649840 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression ISO Vincristine results in increased expression of CEBPB mRNA CTD PMID:16001973 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Celf1 CUGBP, Elav-like family member 1 decreases expression ISO Vincristine results in decreased expression of CELF1 mRNA CTD PMID:23649840 NCBI chr 3:76,924,591...76,999,429
Ensembl chr 3:76,924,613...76,999,426 		JBrowse link
G Cenpc centromere protein C decreases expression ISO Vincristine results in decreased expression of CENPC1 mRNA CTD PMID:23649840 NCBI chr14:21,988,067...22,046,732
Ensembl chr14:21,988,144...22,055,476 		JBrowse link
G Cenpf centromere protein F decreases expression ISO Vincristine results in decreased expression of CENPF mRNA CTD PMID:23649840 NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669 		JBrowse link
G Cenpi centromere protein I decreases expression ISO Vincristine results in decreased expression of CENPI mRNA CTD PMID:23649840 NCBI chr  X:97,515,919...97,567,671
Ensembl chr  X:97,515,972...97,567,657 		JBrowse link
G Cenpu centromere protein U decreases expression ISO Vincristine results in decreased expression of CENPU mRNA CTD PMID:23649840 NCBI chr16:45,715,821...45,739,038
Ensembl chr16:45,714,294...45,738,823 		JBrowse link
G Cep135 centrosomal protein 135 increases expression ISO Vincristine results in increased expression of CEP135 mRNA CTD PMID:23649840 NCBI chr14:31,530,538...31,595,812
Ensembl chr14:31,531,482...31,595,772 		JBrowse link
G Ces5a carboxylesterase 5A increases expression ISO Vincristine results in increased expression of CES5A mRNA CTD PMID:23649840 NCBI chr19:11,469,431...11,499,007
Ensembl chr19:11,469,469...11,499,006 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression ISO Vincristine results in increased expression of CFLAR mRNA CTD PMID:23649840 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034 		JBrowse link
G Chd1l chromodomain helicase DNA binding protein 1-like increases expression ISO Vincristine results in increased expression of CHD1L mRNA CTD PMID:23649840 NCBI chr 2:185,138,526...185,217,498
Ensembl chr 2:185,139,308...185,217,595 		JBrowse link
G Chek2 checkpoint kinase 2 decreases expression ISO Vincristine results in decreased expression of CHEK2 mRNA CTD PMID:23649840 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Chm CHM Rab escort protein increases expression ISO Vincristine results in increased expression of CHM mRNA CTD PMID:23649840 NCBI chr  X:78,203,200...78,361,996
Ensembl chr  X:78,203,204...78,361,943 		JBrowse link
G Chml CHM like Rab escort protein decreases expression ISO Vincristine results in decreased expression of CHML mRNA CTD PMID:23649840 NCBI chr13:87,609,647...87,619,868
Ensembl chr13:87,589,298...87,619,862 		JBrowse link
G Chtf18 chromosome transmission fidelity factor 18 decreases expression ISO Vincristine results in decreased expression of CHTF18 mRNA CTD PMID:23649840 NCBI chr10:14,743,006...14,751,044
Ensembl chr10:14,742,621...14,751,050 		JBrowse link
G Ciapin1 cytokine induced apoptosis inhibitor 1 decreases response to substance ISO CIAPIN1 protein results in decreased susceptibility to Vincristine CTD PMID:18389626 NCBI chr19:10,179,963...10,195,511
Ensembl chr19:10,180,100...10,195,503 		JBrowse link
G Cirbp cold inducible RNA binding protein decreases expression ISO Vincristine results in decreased expression of CIRBP mRNA CTD PMID:23649840 NCBI chr 7:9,533,857...9,538,899
Ensembl chr 7:9,424,178...9,538,818 		JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 increases expression ISO Vincristine results in increased expression of CLASP2 mRNA CTD PMID:23649840 NCBI chr 8:113,677,345...113,859,957
Ensembl chr 8:113,677,284...113,858,731 		JBrowse link
G Clec2d C-type lectin domain family 2, member D decreases expression ISO Vincristine results in decreased expression of CLEC2D mRNA CTD PMID:23649840 NCBI chr 4:162,216,052...162,239,530
Ensembl chr 4:162,216,572...162,239,527 		JBrowse link
G Clic2 chloride intracellular channel 2 increases expression ISO Vincristine results in increased expression of CLIC2 mRNA CTD PMID:23649840 NCBI chr20:149,337...164,375
Ensembl chr20:148,907...164,355 		JBrowse link
G Clspn claspin decreases expression ISO Vincristine results in decreased expression of CLSPN mRNA CTD PMID:23649840 NCBI chr 5:138,850,119...138,885,037
Ensembl chr 5:138,850,128...138,885,034 		JBrowse link
G Cnksr2 connector enhancer of kinase suppressor of Ras 2 decreases expression ISO Vincristine results in decreased expression of CNKSR2 mRNA CTD PMID:23649840 NCBI chr  X:36,908,135...37,148,337
Ensembl chr  X:36,907,850...37,150,555 		JBrowse link
G Cnot3 CCR4-NOT transcription complex, subunit 3 decreases expression ISO Vincristine results in decreased expression of CNOT3 mRNA CTD PMID:23649840 NCBI chr 1:65,555,924...65,572,167
Ensembl chr 1:65,555,924...65,572,167 		JBrowse link
G Cnot6l CCR4-NOT transcription complex, subunit 6-like decreases expression ISO Vincristine results in decreased expression of CNOT6L mRNA CTD PMID:23649840 NCBI chr14:13,410,499...13,502,511
Ensembl chr14:13,411,281...13,498,203 		JBrowse link
G Cntln centlein decreases expression ISO Vincristine results in decreased expression of CNTLN mRNA CTD PMID:23649840 NCBI chr 5:99,295,865...99,576,402
Ensembl chr 5:99,296,000...99,576,396 		JBrowse link
G Col15a1 collagen type XV alpha 1 chain decreases response to substance ISO COL15A1 mRNA results in decreased susceptibility to Vincristine CTD PMID:25199881 NCBI chr 5:61,501,963...61,607,591
Ensembl chr 5:61,501,963...61,607,591 		JBrowse link
G Col1a2 collagen type I alpha 2 chain increases response to substance ISO COL1A2 mRNA results in increased susceptibility to Vincristine CTD PMID:25199881 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867 		JBrowse link
G Col3a1 collagen type III alpha 1 chain decreases response to substance ISO COL3A1 mRNA results in decreased susceptibility to Vincristine CTD PMID:25199881 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547 		JBrowse link
G Col5a2 collagen type V alpha 2 chain decreases response to substance ISO COL5A2 mRNA results in decreased susceptibility to Vincristine CTD PMID:25199881 NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154 		JBrowse link
G Comtd1 catechol-O-methyltransferase domain containing 1 decreases expression ISO Vincristine results in decreased expression of COMTD1 mRNA CTD PMID:23649840 NCBI chr15:2,459,783...2,462,895
Ensembl chr15:2,459,783...2,462,895 		JBrowse link
G Cp ceruloplasmin increases expression EXP Vincristine results in increased expression of CP mRNA CTD PMID:20624997 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075 		JBrowse link
G Cpeb2 cytoplasmic polyadenylation element binding protein 2 increases expression ISO Vincristine results in increased expression of CPEB2 mRNA CTD PMID:23649840 NCBI chr14:67,787,503...67,839,973
Ensembl chr14:67,787,507...67,840,743 		JBrowse link
G Cpne3 copine 3 decreases expression ISO Vincristine results in decreased expression of CPNE3 mRNA CTD PMID:23649840 NCBI chr 5:33,014,658...33,063,934
Ensembl chr 5:33,016,307...33,063,934 		JBrowse link
G Cpsf6 cleavage and polyadenylation specific factor 6 decreases expression ISO Vincristine results in decreased expression of CPSF6 mRNA CTD PMID:23649840 NCBI chr 7:52,956,589...53,001,783
Ensembl chr 7:52,956,589...52,988,122 		JBrowse link
G Crebbp CREB binding protein increases expression ISO Vincristine results in increased expression of CREBBP mRNA CTD PMID:23649840 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888 		JBrowse link
G Crebrf CREB3 regulatory factor increases expression ISO Vincristine results in increased expression of CREBRF mRNA CTD PMID:23649840 NCBI chr10:16,399,170...16,479,650
Ensembl chr10:16,404,596...16,461,999 		JBrowse link
G Crebzf CREB/ATF bZIP transcription factor decreases expression ISO Vincristine results in decreased expression of CREBZF mRNA CTD PMID:23649840 NCBI chr 1:144,416,864...144,423,540
Ensembl chr 1:144,417,446...144,428,553 		JBrowse link
G Crtap cartilage associated protein decreases expression ISO Vincristine results in decreased expression of CRTAP mRNA CTD PMID:23649840 NCBI chr 8:114,047,929...114,067,636
Ensembl chr 8:114,047,933...114,067,631 		JBrowse link
G Crtc3 CREB regulated transcription coactivator 3 increases expression ISO Vincristine results in increased expression of CRTC3 mRNA CTD PMID:23649840 NCBI chr 1:134,552,830...134,655,929
Ensembl chr 1:134,554,696...134,655,500 		JBrowse link
G Csad cysteine sulfinic acid decarboxylase decreases expression ISO Vincristine results in decreased expression of CSAD mRNA CTD PMID:23649840 NCBI chr 7:133,308,571...133,337,914
Ensembl chr 7:133,308,574...133,337,615 		JBrowse link
G Csf2 colony stimulating factor 2 increases expression ISO Vincristine results in increased expression of CSF2 mRNA CTD PMID:23649840 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 increases expression ISO Vincristine results in increased expression of CSNK1A1 mRNA CTD PMID:23649840 NCBI chr18:55,017,049...55,050,184
Ensembl chr18:55,017,055...55,049,271 		JBrowse link
G Csnk1g1 casein kinase 1, gamma 1 increases expression ISO Vincristine results in increased expression of CSNK1G1 mRNA CTD PMID:23649840 NCBI chr 8:66,439,760...66,577,247
Ensembl chr 8:66,439,864...66,572,826 		JBrowse link
G Csta cystatin A increases expression ISO Vincristine results in increased expression of CSTA mRNA CTD PMID:23649840 NCBI chr11:64,620,483...64,631,488
Ensembl chr11:64,620,483...64,631,488 		JBrowse link
G Cstf1 cleavage stimulation factor subunit 1 decreases expression ISO Vincristine results in decreased expression of CSTF1 mRNA CTD PMID:23649840 NCBI chr 3:161,144,522...161,156,294
Ensembl chr 3:161,144,548...161,156,300 		JBrowse link
G Ctc1 CST telomere replication complex component 1 decreases expression ISO Vincristine results in decreased expression of CTC1 mRNA CTD PMID:23649840 NCBI chr10:53,714,614...53,735,298
Ensembl chr10:53,714,644...53,735,298 		JBrowse link
G Cth cystathionine gamma-lyase increases expression ISO Vincristine results in increased expression of CTH mRNA CTD PMID:23649840 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234 		JBrowse link
G Ctnnal1 catenin alpha-like 1 decreases expression ISO Vincristine results in decreased expression of CTNNAL1 mRNA CTD PMID:23649840 NCBI chr 5:71,514,340...71,569,431
Ensembl chr 5:71,514,340...71,569,431 		JBrowse link
G Ctnnb1 catenin beta 1 increases expression
decreases response to substance		 ISO Vincristine results in increased expression of CTNNB1 mRNA
CTNNB1 results in decreased susceptibility to Vincristine		 CTD PMID:22000491 PMID:23649840 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cul4a cullin 4A increases expression ISO Vincristine results in increased expression of CUL4A mRNA CTD PMID:23649840 NCBI chr16:76,385,298...76,422,316
Ensembl chr16:76,384,546...76,422,330 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression ISO Vincristine results in increased expression of CXCL10 mRNA CTD PMID:23649840 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 increases expression ISO Vincristine results in increased expression of CXCL11 mRNA CTD PMID:23649840 NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression
multiple interactions		 ISO Vincristine results in increased expression of CXCL12 mRNA
KN 93 inhibits the reaction [Vincristine results in increased expression of CXCL12 mRNA]		 CTD PMID:34286406 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 increases expression ISO Vincristine results in increased expression of CXCL9 mRNA CTD PMID:23649840 NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435 		JBrowse link
G Cyld CYLD lysine 63 deubiquitinase increases expression ISO Vincristine results in increased expression of CYLD mRNA CTD PMID:23649840 NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658 		JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 increases response to substance ISO CYP2C8 gene SNP results in increased susceptibility to Vincristine CTD PMID:21245421
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases metabolic processing ISO CYP3A4 protein results in increased metabolism of Vincristine CTD PMID:19346885 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions
increases metabolic processing		 ISO [CYP3A5 gene polymorphism results in increased activity of CYP3A5 protein] which results in increased metabolism of Vincristine
CYP3A5 protein results in increased metabolism of Vincristine		 CTD PMID:21225912 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422 		JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 increases expression ISO Vincristine results in increased expression of CYP4F3 mRNA CTD PMID:23649840 NCBI chr16:17,763,543...17,804,944
Ensembl chr16:17,707,317...17,804,940 		JBrowse link
G Cyp4v3 cytochrome P450, family 4, subfamily v, polypeptide 3 decreases expression ISO Vincristine results in decreased expression of CYP4V2 mRNA CTD PMID:23649840 NCBI chr16:46,917,929...46,958,735
Ensembl chr16:46,918,401...46,943,395 		JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 decreases expression ISO Vincristine results in decreased expression of CYSLTR1 mRNA CTD PMID:23649840 NCBI chr  X:71,661,421...71,690,012
Ensembl chr  X:71,663,821...71,690,121 		JBrowse link
G Daam1 dishevelled associated activator of morphogenesis 1 increases expression ISO Vincristine results in increased expression of DAAM1 mRNA CTD PMID:23649840 NCBI chr 6:90,389,544...90,550,114
Ensembl chr 6:90,389,688...90,550,114 		JBrowse link
G Dcaf8 DDB1 and CUL4 associated factor 8 increases expression ISO Vincristine results in increased expression of DCAF8 mRNA CTD PMID:23649840 NCBI chr13:84,609,838...84,667,025
Ensembl chr13:84,610,248...84,669,726 		JBrowse link
G Dcn decorin decreases response to substance ISO DCN mRNA results in decreased susceptibility to Vincristine CTD PMID:25199881 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270 		JBrowse link
G Dcun1d1 defective in cullin neddylation 1 domain containing 1 increases expression ISO Vincristine results in increased expression of DCUN1D1 mRNA CTD PMID:23649840 NCBI chr 2:118,721,275...118,772,606
Ensembl chr 2:118,721,822...118,772,602 		JBrowse link
G Dcun1d4 defective in cullin neddylation 1 domain containing 4 decreases expression ISO Vincristine results in decreased expression of DCUN1D4 mRNA CTD PMID:23649840 NCBI chr14:34,652,723...34,733,122
Ensembl chr14:34,652,723...34,733,207 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Vincristine results in increased expression of DDIT3 mRNA CTD PMID:23649840 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Ddx50 DExD-box helicase 50 increases expression ISO Vincristine results in increased expression of DDX50 mRNA CTD PMID:23649840 NCBI chr20:30,561,623...30,591,324
Ensembl chr20:30,560,544...30,591,152 		JBrowse link
G Ddx52 DExD-box helicase 52 increases expression ISO Vincristine results in increased expression of DDX52 mRNA CTD PMID:23649840 NCBI chr10:68,824,594...68,847,400
Ensembl chr10:68,824,645...68,848,266 		JBrowse link
G Ddx60 DEXD/H-box helicase 60 increases expression ISO Vincristine results in increased expression of DDX60 mRNA CTD PMID:23649840 NCBI chr16:28,077,000...28,197,903
Ensembl chr16:28,076,999...28,179,526 		JBrowse link
G Dennd5a DENN domain containing 5A increases expression ISO Vincristine results in increased expression of DENND5A mRNA CTD PMID:23649840 NCBI chr 1:163,928,183...163,994,207
Ensembl chr 1:163,928,183...163,994,316 		JBrowse link
G Dgcr8 DGCR8 microprocessor complex subunit decreases expression ISO Vincristine results in decreased expression of DGCR8 mRNA CTD PMID:23649840 NCBI chr11:82,704,673...82,737,251
Ensembl chr11:82,704,729...82,737,242 		JBrowse link
G Dhfr dihydrofolate reductase decreases expression ISO Vincristine results in decreased expression of DHFR mRNA CTD PMID:23649840 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
G Dhrs11 dehydrogenase/reductase 11 decreases expression ISO Vincristine results in decreased expression of DHRS11 mRNA CTD PMID:23649840 NCBI chr10:69,698,214...69,708,294
Ensembl chr10:69,698,214...69,708,295 		JBrowse link
G Dhrs2 dehydrogenase/reductase 2 increases expression ISO Vincristine results in increased expression of DHRS2 mRNA CTD PMID:23649840 NCBI chr15:28,688,881...28,703,646
Ensembl chr15:28,688,940...28,703,644 		JBrowse link
G Dhrs7 dehydrogenase/reductase 7 increases expression ISO Vincristine results in increased expression of DHRS7 mRNA CTD PMID:23649840 NCBI chr 6:91,332,259...91,347,856
Ensembl chr 6:91,251,323...91,347,892 		JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein decreases expression ISO Vincristine results in decreased expression of DIABLO mRNA CTD PMID:23649840 NCBI chr12:33,055,784...33,070,401
Ensembl chr12:33,055,263...33,070,387 		JBrowse link
G Dido1 death inducer-obliterator 1 decreases expression ISO Vincristine results in decreased expression of DIDO1 mRNA CTD PMID:23649840 NCBI chr 3:167,772,535...167,825,894
Ensembl chr 3:167,772,770...167,817,218 		JBrowse link
G Dip2a disco-interacting protein 2 homolog A increases expression ISO Vincristine results in increased expression of DIP2A mRNA CTD PMID:23649840 NCBI chr20:12,284,566...12,371,068
Ensembl chr20:12,284,654...12,370,217 		JBrowse link
G Dmd dystrophin increases expression ISO Vincristine results in increased expression of DMD mRNA CTD PMID:23649840 NCBI chr  X:47,272,324...49,504,219
Ensembl chr  X:47,272,331...49,504,207 		JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 decreases expression ISO Vincristine results in decreased expression of DNAJB1 mRNA CTD PMID:23649840 NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458 		JBrowse link
G Dnajc7 DnaJ heat shock protein family (Hsp40) member C7 increases expression ISO Vincristine results in increased expression of DNAJC7 mRNA CTD PMID:23649840 NCBI chr10:85,518,637...85,555,079
Ensembl chr10:85,518,621...85,555,575 		JBrowse link
G Dnase1l3 deoxyribonuclease 1L3 decreases expression ISO Vincristine results in decreased expression of DNASE1L3 mRNA CTD PMID:23649840 NCBI chr15:16,922,335...16,948,322
Ensembl chr15:16,922,335...16,948,317 		JBrowse link
G Dnmbp dynamin binding protein decreases expression ISO Vincristine results in decreased expression of DNMBP mRNA CTD PMID:23649840 NCBI chr 1:242,736,189...242,829,431
Ensembl chr 1:242,736,189...242,802,604 		JBrowse link
G Dock4 dedicator of cytokinesis 4 increases expression ISO Vincristine results in increased expression of DOCK4 mRNA CTD PMID:23649840 NCBI chr 6:57,512,929...57,902,597
Ensembl chr 6:57,512,908...57,901,855 		JBrowse link
G Dock8 dedicator of cytokinesis 8 decreases expression ISO Vincristine results in decreased expression of DOCK8 mRNA CTD PMID:23649840 NCBI chr 1:222,649,309...222,842,474
Ensembl chr 1:222,649,309...222,842,474 		JBrowse link
G Dok4 docking protein 4 increases expression ISO Vincristine results in increased expression of DOK4 mRNA CTD PMID:23649840 NCBI chr19:10,146,520...10,157,187
Ensembl chr19:10,146,474...10,158,203 		JBrowse link
G Donson DNA replication fork stabilization factor DONSON decreases expression ISO Vincristine results in decreased expression of DONSON mRNA CTD PMID:23649840 NCBI chr11:30,919,834...30,933,150
Ensembl chr11:30,923,239...30,932,889 		JBrowse link
G Dpp4 dipeptidylpeptidase 4 decreases expression ISO Vincristine results in decreased expression of DPP4 mRNA CTD PMID:23649840 NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901 		JBrowse link
G Dpyd dihydropyrimidine dehydrogenase increases response to substance ISO DPYD gene SNP results in increased susceptibility to Vincristine CTD PMID:20864405 NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982 		JBrowse link
G Dram1 DNA-damage regulated autophagy modulator 1 increases expression ISO Vincristine results in increased expression of DRAM1 mRNA CTD PMID:23649840 NCBI chr 7:22,742,794...22,776,888
Ensembl chr 7:22,742,849...22,776,765 		JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase homolog decreases expression ISO Vincristine results in decreased expression of DTL mRNA CTD PMID:23649840 NCBI chr13:103,115,810...103,155,029
Ensembl chr13:103,117,186...103,154,890 		JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Vincristine results in increased expression of DUSP1 mRNA CTD PMID:23649840 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Dusp10 dual specificity phosphatase 10 increases expression ISO Vincristine results in increased expression of DUSP10 mRNA CTD PMID:23649840 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716 		JBrowse link
G Dusp16 dual specificity phosphatase 16 increases expression ISO Vincristine results in increased expression of DUSP16 mRNA CTD PMID:23649840 NCBI chr 4:167,546,780...167,630,173
Ensembl chr 4:167,548,155...167,629,980 		JBrowse link
G Dusp2 dual specificity phosphatase 2 increases expression ISO Vincristine results in increased expression of DUSP2 mRNA CTD PMID:23649840 NCBI chr 3:114,556,325...114,558,510
Ensembl chr 3:114,556,325...114,558,499 		JBrowse link
G Dusp4 dual specificity phosphatase 4 increases expression ISO Vincristine results in increased expression of DUSP4 mRNA CTD PMID:23649840 NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138 		JBrowse link
G Dynlt2 dynein light chain Tctex-type 2 decreases expression ISO Vincristine results in decreased expression of DYNLT2 mRNA CTD PMID:23649840 NCBI chr 1:55,971,285...55,983,249
Ensembl chr 1:55,971,283...55,983,307 		JBrowse link
G E2f8 E2F transcription factor 8 decreases expression ISO Vincristine results in decreased expression of E2F8 mRNA CTD PMID:23649840 NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098 		JBrowse link
G Ebf1 EBF transcription factor 1 increases expression ISO Vincristine results in increased expression of EBF1 mRNA CTD PMID:23649840 NCBI chr10:29,095,858...29,489,142
Ensembl chr10:29,099,933...29,487,665 		JBrowse link
G Ednrb endothelin receptor type B increases expression EXP Vincristine results in increased expression of EDNRB mRNA CTD PMID:20624997 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
G Efna4 ephrin A4 decreases expression ISO Vincristine results in decreased expression of EFNA4 mRNA CTD PMID:23649840 NCBI chr 2:174,748,729...174,752,979
Ensembl chr 2:174,748,724...174,752,979 		JBrowse link
G Egfl6 EGF-like-domain, multiple 6 decreases response to substance ISO EGFL6 mRNA results in decreased susceptibility to Vincristine CTD PMID:25199881 NCBI chr  X:27,884,087...27,942,044
Ensembl chr  X:27,884,125...27,942,044 		JBrowse link
G Egr1 early growth response 1 increases expression ISO Vincristine results in increased expression of EGR1 mRNA CTD PMID:12706485 PMID:23649840 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Egr3 early growth response 3 increases expression ISO Vincristine results in increased expression of EGR3 mRNA CTD PMID:23649840 NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627 		JBrowse link
G Ehbp1l1 EH domain binding protein 1-like 1 decreases expression ISO Vincristine results in decreased expression of EHBP1L1 mRNA CTD PMID:23649840 NCBI chr 1:202,994,115...203,014,320
Ensembl chr 1:202,994,118...203,014,270 		JBrowse link
G Eif1 eukaryotic translation initiation factor 1 decreases expression ISO Vincristine results in decreased expression of EIF1 mRNA CTD PMID:23649840 NCBI chr10:85,246,751...85,248,842
Ensembl chr10:85,246,764...85,427,327 		JBrowse link
G Eif1ad eukaryotic translation initiation factor 1A domain containing decreases expression ISO Vincristine results in decreased expression of EIF1AD mRNA CTD PMID:23649840 NCBI chr 1:202,674,362...202,679,662
Ensembl chr 1:202,674,185...202,679,658 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases expression
multiple interactions		 EXP Vincristine results in increased expression of EIF2AK3 mRNA
Quercetin inhibits the reaction [Vincristine results in increased expression of EIF2AK3 mRNA]		 CTD PMID:33038355 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Eif3b eukaryotic translation initiation factor 3, subunit B decreases expression ISO Vincristine results in decreased expression of EIF3B mRNA CTD PMID:23649840 NCBI chr12:14,196,403...14,220,865
Ensembl chr12:14,196,403...14,220,886 		JBrowse link
G Eif3m eukaryotic translation initiation factor 3, subunit M increases expression ISO Vincristine results in increased expression of EIF3M mRNA CTD PMID:23649840 NCBI chr 3:91,424,754...91,442,358
Ensembl chr 3:91,416,325...91,442,392 		JBrowse link
G Eif4a1 eukaryotic translation initiation factor 4A1 increases expression ISO Vincristine results in increased expression of EIF4A1 mRNA CTD PMID:23649840 NCBI chr10:54,384,345...54,389,855
Ensembl chr10:54,384,347...54,389,858 		JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 decreases expression ISO Vincristine results in decreased expression of EIF4A2 mRNA CTD PMID:23649840 NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781 		JBrowse link
G Elf3 E74 like ETS transcription factor 3 increases expression ISO Vincristine results in increased expression of ELF3 mRNA CTD PMID:23649840 NCBI chr13:46,690,460...46,695,394
Ensembl chr13:46,690,466...46,695,481 		JBrowse link
G Elk3 ETS transcription factor ELK3 increases expression ISO Vincristine results in increased expression of ELK3 mRNA CTD PMID:23649840 NCBI chr 7:27,768,582...27,831,088
Ensembl chr 7:27,768,599...27,804,084 		JBrowse link
G Eme2 essential meiotic structure-specific endonuclease subunit 2 decreases expression ISO Vincristine results in decreased expression of EME2 mRNA CTD PMID:23649840 NCBI chr10:13,913,216...13,915,991
Ensembl chr10:13,913,221...13,915,968 		JBrowse link
G Eml6 EMAP like 6 decreases expression ISO Vincristine results in decreased expression of EML6 mRNA CTD PMID:23649840 NCBI chr14:103,471,537...103,806,120
Ensembl chr14:103,476,372...103,805,849 		JBrowse link
G Enox1 ecto-NOX disulfide-thiol exchanger 1 increases expression ISO Vincristine results in increased expression of ENOX1 mRNA CTD PMID:23649840 NCBI chr15:52,517,833...53,079,752
Ensembl chr15:52,515,178...53,079,749 		JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 increases expression ISO Vincristine results in increased expression of ENPP2 mRNA CTD PMID:23649840 NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827 		JBrowse link
G Ensa endosulfine alpha decreases expression ISO Vincristine results in decreased expression of ENSA mRNA CTD PMID:23649840 NCBI chr 2:183,185,552...183,192,888
Ensembl chr 2:183,185,552...183,194,847 		JBrowse link
G Entpd2 ectonucleoside triphosphate diphosphohydrolase 2 increases expression ISO Vincristine results in increased expression of ENTPD2 mRNA CTD PMID:23649840 NCBI chr 3:8,213,575...8,219,094
Ensembl chr 3:8,213,663...8,226,866 		JBrowse link
G Eomes eomesodermin decreases expression ISO Vincristine results in decreased expression of EOMES mRNA CTD PMID:23649840 NCBI chr 8:118,181,340...118,189,186
Ensembl chr 8:118,181,777...118,188,316 		JBrowse link
G Epg5 ectopic P-granules 5 autophagy tethering factor increases expression ISO Vincristine results in increased expression of EPG5 mRNA CTD PMID:23649840 NCBI chr18:71,403,990...71,502,079
Ensembl chr18:71,404,010...71,501,502 		JBrowse link
G Ephb1 Eph receptor B1 decreases expression ISO Vincristine results in decreased expression of EPHB1 mRNA CTD PMID:23649840 NCBI chr 8:102,507,549...102,944,839
Ensembl chr 8:102,507,549...102,944,839 		JBrowse link
G Ephx1 epoxide hydrolase 1 decreases expression ISO Vincristine results in decreased expression of EPHX1 mRNA CTD PMID:21382384 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Epm2aip1 EPM2A interacting protein 1 decreases expression ISO Vincristine results in decreased expression of EPM2AIP1 mRNA CTD PMID:23649840 NCBI chr 8:111,233,871...111,241,219
Ensembl chr 8:111,233,826...111,241,871 		JBrowse link
G Epor erythropoietin receptor decreases expression ISO Vincristine results in decreased expression of EPOR mRNA CTD PMID:23649840 NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257 		JBrowse link
G Eprs1 glutamyl-prolyl-tRNA synthetase 1 increases expression EXP Vincristine results in increased expression of EPRS1 mRNA CTD PMID:20624997 NCBI chr13:96,901,548...96,971,966
Ensembl chr13:96,901,575...96,971,966 		JBrowse link
G Epsti1 epithelial stromal interaction 1 increases expression ISO Vincristine results in increased expression of EPSTI1 mRNA CTD PMID:23649840 NCBI chr15:53,283,964...53,382,192
Ensembl chr15:53,284,216...53,382,191 		JBrowse link
G Erich3 glutamate-rich 3 decreases expression ISO Vincristine results in decreased expression of ERICH3 mRNA CTD PMID:23649840 NCBI chr 2:243,615,777...243,717,973
Ensembl chr 2:243,615,872...243,715,317 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 increases expression
multiple interactions		 EXP Vincristine results in increased expression of ERN1 mRNA
Quercetin inhibits the reaction [Vincristine results in increased expression of ERN1 mRNA]		 CTD PMID:33038355 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 decreases expression ISO Vincristine results in decreased expression of ESCO2 mRNA CTD PMID:23649840 NCBI chr15:40,034,566...40,052,295
Ensembl chr15:40,034,568...40,055,306 		JBrowse link
G Esd esterase D decreases expression ISO Vincristine results in decreased expression of ESD mRNA CTD PMID:23649840 NCBI chr15:50,043,634...50,063,134
Ensembl chr15:50,043,632...50,063,144 		JBrowse link
G Esm1 endothelial cell-specific molecule 1 decreases expression EXP Vincristine results in decreased expression of ESM1 mRNA CTD PMID:20624997 NCBI chr 2:44,876,067...44,884,805
Ensembl chr 2:44,876,067...44,884,804 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
decreases expression		 ISO bisphenol A inhibits the reaction [Vincristine results in decreased expression of ESR1 mRNA]; bisphenol A inhibits the reaction [Vincristine results in decreased expression of ESR1 protein]; Diethylhexyl Phthalate inhibits the reaction [Vincristine results in decreased expression of ESR1 mRNA]; Diethylhexyl Phthalate inhibits the reaction [Vincristine results in decreased expression of ESR1 protein]; Vincristine binds to and results in decreased activity of ESR1 protein
Vincristine results in decreased expression of ESR1 mRNA; Vincristine results in decreased expression of ESR1 protein		 CTD PMID:25752796 PMID:35263089 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
decreases expression		 ISO bisphenol A inhibits the reaction [Vincristine results in decreased expression of ESR2 mRNA]; bisphenol A inhibits the reaction [Vincristine results in decreased expression of ESR2 protein]; Diethylhexyl Phthalate inhibits the reaction [Vincristine results in decreased expression of ESR2 mRNA]; Diethylhexyl Phthalate inhibits the reaction [Vincristine results in decreased expression of ESR2 protein]
Vincristine results in decreased expression of ESR2 mRNA; Vincristine results in decreased expression of ESR2 protein		 CTD PMID:35263089 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Evc EvC ciliary complex subunit 1 increases expression ISO Vincristine results in increased expression of EVC mRNA CTD PMID:23649840 NCBI chr14:73,456,181...73,498,955
Ensembl chr14:73,456,222...73,498,099 		JBrowse link
G Exo1 exonuclease 1 decreases expression ISO Vincristine results in decreased expression of EXO1 mRNA CTD PMID:23649840 NCBI chr13:87,809,725...87,834,654
Ensembl chr13:87,809,810...87,834,654 		JBrowse link
G Exog exo/endonuclease G decreases expression ISO Vincristine results in decreased expression of EXOG mRNA CTD PMID:23649840 NCBI chr 8:119,184,974...119,204,819
Ensembl chr 8:119,185,136...119,204,672 		JBrowse link
G Ext1 exostosin glycosyltransferase 1 increases expression ISO Vincristine results in increased expression of EXT1 mRNA CTD PMID:23649840 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357 		JBrowse link
G F2 coagulation factor II, thrombin affects expression ISO Vincristine affects the expression of F2 protein CTD PMID:12542493 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G F3 coagulation factor III, tissue factor increases expression ISO
EXP		 Vincristine results in increased expression of F3 mRNA; Vincristine results in increased expression of F3 protein CTD PMID:12542493 PMID:20624997 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G Fam13b family with sequence similarity 13, member B increases expression ISO Vincristine results in increased expression of FAM13B mRNA CTD PMID:23649840 NCBI chr18:26,040,285...26,107,112
Ensembl chr18:26,040,285...26,106,587 		JBrowse link
G Fam13c family with sequence similarity 13, member C increases expression ISO Vincristine results in increased expression of FAM13C mRNA CTD PMID:23649840 NCBI chr20:18,065,625...18,187,792
Ensembl chr20:18,065,628...18,187,592 		JBrowse link
G Fam171b family with sequence similarity 171, member B decreases expression ISO Vincristine results in decreased expression of FAM171B mRNA CTD PMID:23649840 NCBI chr 3:68,930,755...68,986,113
Ensembl chr 3:68,930,822...68,986,127 		JBrowse link
G Fam174a family with sequence similarity 174, member A increases expression ISO Vincristine results in increased expression of FAM174A mRNA CTD PMID:23649840 NCBI chr 9:95,742,815...95,761,083
Ensembl chr 9:95,742,927...95,761,081 		JBrowse link
G Fam76b family with sequence similarity 76, member B decreases expression ISO Vincristine results in decreased expression of FAM76B mRNA CTD PMID:23649840 NCBI chr 8:10,689,396...10,711,847
Ensembl chr 8:10,688,963...10,711,861 		JBrowse link
G Fam81a family with sequence similarity 81, member A decreases expression ISO Vincristine results in decreased expression of FAM81A mRNA CTD PMID:23649840 NCBI chr 8:70,762,852...70,821,898
Ensembl chr 8:70,763,614...70,821,875 		JBrowse link
G Fam83d family with sequence similarity 83, member D decreases expression ISO Vincristine results in decreased expression of FAM83D mRNA CTD PMID:23649840 NCBI chr 3:147,421,941...147,441,211
Ensembl chr 3:147,421,908...147,441,192 		JBrowse link
G Fancf FA complementation group F decreases expression ISO Vincristine results in decreased expression of FANCF mRNA CTD PMID:23649840 NCBI chr 1:101,449,120...101,451,936
Ensembl chr 1:101,450,389...101,451,923 		JBrowse link
G Fancg FA complementation group G decreases expression ISO Vincristine results in decreased expression of FANCG mRNA CTD PMID:23649840 NCBI chr 5:57,230,287...57,240,067
Ensembl chr 5:57,231,685...57,240,029 		JBrowse link
G Fas Fas cell surface death receptor increases expression ISO Vincristine results in increased expression of FAS mRNA CTD PMID:23649840 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand increases expression ISO Vincristine results in increased expression of FASLG protein CTD PMID:11716366 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fastkd2 FAST kinase domains 2 decreases expression ISO Vincristine results in decreased expression of FASTKD2 mRNA CTD PMID:23649840 NCBI chr 9:65,166,148...65,188,184
Ensembl chr 9:65,168,228...65,188,174 		JBrowse link
G Fbxl20 F-box and leucine-rich repeat protein 20 decreases expression ISO Vincristine results in decreased expression of FBXL20 mRNA CTD PMID:23649840 NCBI chr10:83,080,568...83,143,680
Ensembl chr10:83,086,551...83,144,162 		JBrowse link
G Fbxl4 F-box and leucine-rich repeat protein 4 decreases expression ISO Vincristine results in decreased expression of FBXL4 mRNA CTD PMID:23649840 NCBI chr 5:35,955,801...36,029,446
Ensembl chr 5:35,955,812...36,029,443 		JBrowse link
G Fbxo33 F-box protein 33 decreases expression ISO Vincristine results in decreased expression of FBXO33 mRNA CTD PMID:23649840 NCBI chr 6:76,900,619...76,934,232
Ensembl chr 6:76,900,631...76,932,669 		JBrowse link
G Fbxo5 F-box protein 5 decreases expression ISO Vincristine results in decreased expression of FBXO5 mRNA CTD PMID:23649840 NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437 		JBrowse link
G Fbxo9 f-box protein 9 decreases expression ISO Vincristine results in decreased expression of FBXO9 mRNA CTD PMID:23649840 NCBI chr 8:78,958,482...78,984,015
Ensembl chr 8:78,958,483...78,983,949 		JBrowse link
G Fcgr2b Fc gamma receptor 2B increases expression EXP Vincristine results in increased expression of FCGR2B mRNA CTD PMID:20624997 NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 increases expression ISO Vincristine results in increased expression of FDFT1 mRNA CTD PMID:23649840 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287 		JBrowse link
G Fermt2 FERM domain containing kindlin 2 increases expression ISO Vincristine results in increased expression of FERMT2 mRNA CTD PMID:23649840 NCBI chr15:18,682,927...18,751,959
Ensembl chr15:18,682,927...18,751,811 		JBrowse link
G Ffar2 free fatty acid receptor 2 decreases expression ISO Vincristine results in decreased expression of FFAR2 mRNA CTD PMID:23649840 NCBI chr 1:86,071,855...86,075,049
Ensembl chr 1:86,072,184...86,075,033 		JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase decreases expression ISO Vincristine results in decreased expression of FGR mRNA CTD PMID:23649840 NCBI chr 5:145,189,814...145,219,571
Ensembl chr 5:145,189,841...145,217,326 		JBrowse link
G Flot2 flotillin 2 decreases expression ISO Vincristine results in decreased expression of FLOT2 mRNA CTD PMID:23649840 NCBI chr10:62,926,047...62,947,759
Ensembl chr10:62,920,665...62,947,756 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 decreases expression ISO Vincristine results in decreased expression of FLT1 mRNA CTD PMID:23649840 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626 		JBrowse link
G Fmnl3 formin-like 3 increases expression ISO Vincristine results in increased expression of FMNL3 mRNA CTD PMID:23649840 NCBI chr 7:130,454,270...130,505,626
Ensembl chr 7:130,454,275...130,505,626 		JBrowse link
G Fnbp1 formin binding protein 1 increases expression ISO Vincristine results in increased expression of FNBP1 mRNA CTD PMID:23649840 NCBI chr 3:14,309,067...14,424,378
Ensembl chr 3:14,309,640...14,424,881 		JBrowse link
G Fnbp4 formin binding protein 4 increases expression ISO Vincristine results in increased expression of FNBP4 mRNA CTD PMID:23649840 NCBI chr 3:76,733,012...76,763,077
Ensembl chr 3:76,733,027...76,763,079 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Vincristine results in increased expression of FOS protein CTD PMID:18930597 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit increases expression ISO Vincristine results in increased expression of FOSL2 mRNA CTD PMID:23649840 NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034 		JBrowse link
G Foxk2 forkhead box K2 decreases expression ISO Vincristine results in decreased expression of FOXK2 mRNA CTD PMID:23649840 NCBI chr10:106,542,643...106,592,569
Ensembl chr10:106,542,566...106,592,563 		JBrowse link
G Foxo1 forkhead box O1 multiple interactions
decreases expression		 EXP Quercetin inhibits the reaction [Vincristine results in decreased expression of FOXO1 mRNA] CTD PMID:33038355 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G Foxp1 forkhead box P1 increases expression ISO Vincristine results in increased expression of FOXP1 mRNA CTD PMID:23649840 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G Fry FRY microtubule binding protein decreases expression ISO Vincristine results in decreased expression of FRY mRNA CTD PMID:23649840 NCBI chr12:4,493,890...4,887,118
Ensembl chr12:4,493,891...4,799,116 		JBrowse link
G Fscn1 fascin actin-bundling protein 1 increases expression ISO Vincristine results in increased expression of FSCN1 mRNA CTD PMID:23649840 NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211 		JBrowse link
G Fsd1l fibronectin type III and SPRY domain containing 1-like increases expression ISO Vincristine results in increased expression of FSD1L mRNA CTD PMID:23649840 NCBI chr 5:68,258,877...68,334,931
Ensembl chr 5:68,258,932...68,334,928 		JBrowse link
G Fubp1 far upstream element binding protein 1 decreases expression ISO Vincristine results in decreased expression of FUBP1 mRNA CTD PMID:23649840 NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602 		JBrowse link
G Fut11 fucosyltransferase 11 decreases expression ISO Vincristine results in decreased expression of FUT11 mRNA CTD PMID:23649840 NCBI chr15:3,598,768...3,602,328
Ensembl chr15:3,598,758...3,602,356 		JBrowse link
G G3bp1 G3BP stress granule assembly factor 1 increases expression ISO Vincristine results in increased expression of G3BP1 mRNA CTD PMID:23649840 NCBI chr10:39,586,864...39,620,268
Ensembl chr10:39,586,864...39,620,268 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression EXP
ISO		 Vincristine results in increased expression of GADD45A mRNA CTD PMID:20624997 PMID:23649840 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta increases expression EXP Vincristine results in increased expression of GADD45B mRNA CTD PMID:20624997 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046 		JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma increases expression EXP Vincristine results in increased expression of GADD45G mRNA CTD PMID:20624997 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610 		JBrowse link
G Garin1b golgi associated RAB2 interactor 1B increases expression ISO Vincristine results in increased expression of GARIN1B mRNA CTD PMID:23649840 NCBI chr 4:57,915,184...57,938,593
Ensembl chr 4:57,920,790...57,938,591 		JBrowse link
G Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase decreases expression ISO Vincristine results in decreased expression of GART mRNA CTD PMID:23649840 NCBI chr11:30,864,896...30,891,125
Ensembl chr11:30,865,889...30,891,125 		JBrowse link
G Gas7 growth arrest specific 7 decreases expression EXP Vincristine results in decreased expression of GAS7 mRNA CTD PMID:20624997 NCBI chr10:52,152,718...52,383,283
Ensembl chr10:52,152,493...52,383,276 		JBrowse link
G Gbp1 guanylate binding protein 1 increases expression ISO Vincristine results in increased expression of GBP1 mRNA CTD PMID:23649840 NCBI chr 2:231,398,136...231,432,773
Ensembl chr 2:231,398,163...231,432,131
Ensembl chr 2:231,398,163...231,432,131 		JBrowse link
G Gbp2 guanylate binding protein 2 increases expression ISO Vincristine results in increased expression of GBP2 mRNA CTD PMID:23649840 NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571 		JBrowse link
G Gbp6 guanylate binding protein family member 6 decreases expression ISO Vincristine results in decreased expression of GBP6 mRNA CTD PMID:23649840 NCBI chr14:4,730,286...4,756,508
Ensembl chr14:4,730,453...4,839,062
Ensembl chr14:4,730,453...4,839,062 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO [GCLC protein co-treated with GCLM protein] results in decreased susceptibility to Vincristine CTD PMID:10900222 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions
decreases expression		 ISO [GCLC protein co-treated with GCLM protein] results in decreased susceptibility to Vincristine
Vincristine results in decreased expression of GCLM mRNA		 CTD PMID:10900222 PMID:23649840 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Vincristine results in increased expression of GDF15 mRNA CTD PMID:23649840 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055 		JBrowse link
G Gfap glial fibrillary acidic protein increases expression
multiple interactions		 EXP
ISO		 Vincristine results in increased expression of GFAP protein
Ascorbic Acid inhibits the reaction [Vincristine results in increased expression of GFAP protein]; KN 93 inhibits the reaction [Vincristine results in increased expression of GFAP protein]
Quercetin inhibits the reaction [Vincristine results in increased expression of GFAP protein]		 CTD PMID:33038355 PMID:34286406 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589 		JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor decreases expression ISO Vincristine results in decreased expression of GFI1 mRNA CTD PMID:23649840 NCBI chr14:2,040,576...2,056,874
Ensembl chr14:2,042,434...2,051,814 		JBrowse link
G Gfm1 G elongation factor, mitochondrial 1 increases expression ISO Vincristine results in increased expression of GFM1 mRNA CTD PMID:23649840 NCBI chr 2:151,700,573...151,745,477
Ensembl chr 2:151,700,564...151,745,471 		JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression
multiple interactions		 ISO Vincristine results in increased expression of GJA1 mRNA; Vincristine results in increased expression of GJA1 protein
Ascorbic Acid inhibits the reaction [Vincristine results in increased expression of GJA1 mRNA]; Ascorbic Acid inhibits the reaction [Vincristine results in increased expression of GJA1 protein]; gap 27 peptide inhibits the reaction [Vincristine results in increased expression of GJA1 mRNA]; gap 27 peptide inhibits the reaction [Vincristine results in increased expression of GJA1 protein]; GJA1 protein promotes the reaction [Vincristine results in increased secretion of IL1B protein]; GJA1 protein promotes the reaction [Vincristine results in increased secretion of IL6 protein]; KN 62 inhibits the reaction [Vincristine results in increased expression of GJA1 protein]; KN 93 inhibits the reaction [Vincristine results in increased expression of GJA1 mRNA]; KN 93 inhibits the reaction [Vincristine results in increased expression of GJA1 protein]; zinc chloride inhibits the reaction [Vincristine results in increased expression of GJA1 protein]		 CTD PMID:34286406 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gjc1 gap junction protein, gamma 1 decreases expression ISO Vincristine results in decreased expression of GJC1 mRNA CTD PMID:23649840 NCBI chr10:87,758,192...87,785,443
Ensembl chr10:87,760,528...87,785,867 		JBrowse link
G Gli1 GLI family zinc finger 1 increases response to substance ISO GLI1 gene SNP results in increased susceptibility to Vincristine CTD PMID:20864405 NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251 		JBrowse link
G Glipr1 GLI pathogenesis-related 1 increases expression ISO Vincristine results in increased expression of GLIPR1 mRNA CTD PMID:23649840 NCBI chr 7:47,487,342...47,498,974
Ensembl chr 7:47,487,345...47,498,429 		JBrowse link
G Gmfb glia maturation factor, beta increases expression ISO Vincristine results in increased expression of GMFB mRNA CTD PMID:23649840 NCBI chr15:20,069,923...20,081,005
Ensembl chr15:20,067,263...20,080,331 		JBrowse link
G Gmppb GDP-mannose pyrophosphorylase B decreases expression ISO Vincristine results in decreased expression of GMPPB mRNA CTD PMID:23649840 NCBI chr 8:108,737,429...108,740,437
Ensembl chr 8:108,693,060...108,767,286 		JBrowse link
G Gna15 G protein subunit alpha 15 increases expression ISO Vincristine results in increased expression of GNA15 mRNA CTD PMID:23649840 NCBI chr 7:8,184,632...8,205,508
Ensembl chr 7:8,184,861...8,205,508 		JBrowse link
G Gng2 G protein subunit gamma 2 increases expression ISO Vincristine results in increased expression of GNG2 mRNA CTD PMID:23649840 NCBI chr15:4,316,038...4,416,918
Ensembl chr15:4,316,059...4,417,183 		JBrowse link
G Gon4l gon-4 like increases expression ISO Vincristine results in increased expression of GON4L mRNA CTD PMID:23649840 NCBI chr 2:174,233,461...174,306,636
Ensembl chr 2:174,233,461...174,306,634 		JBrowse link
G Gopc golgi associated PDZ and coiled-coil motif containing decreases expression ISO Vincristine results in decreased expression of GOPC mRNA CTD PMID:23649840 NCBI chr20:31,727,617...31,776,904
Ensembl chr20:31,727,620...31,776,903 		JBrowse link
G Gpatch11 G patch domain containing 11 decreases expression ISO Vincristine results in decreased expression of GPATCH11 mRNA CTD PMID:23649840 NCBI chr 6:16,229,933...16,243,305
Ensembl chr 6:16,233,059...16,243,238 		JBrowse link
G Gpatch2 G patch domain containing 2 increases expression ISO Vincristine results in increased expression of GPATCH2 mRNA CTD PMID:23649840 NCBI chr13:98,784,993...98,925,696
Ensembl chr13:98,784,969...98,925,661 		JBrowse link
G Gpatch2l G patch domain containing 2-like increases expression ISO Vincristine results in increased expression of GPATCH2L mRNA CTD PMID:23649840 NCBI chr 6:105,883,383...105,935,644
Ensembl chr 6:105,883,460...105,934,888 		JBrowse link
G Gpbp1l1 GC-rich promoter binding protein 1-like 1 increases expression ISO Vincristine results in increased expression of GPBP1L1 mRNA CTD PMID:23649840 NCBI chr 5:130,009,768...130,050,636
Ensembl chr 5:130,023,137...130,050,459 		JBrowse link
G Gpc3 glypican 3 increases response to substance ISO GPC3 mRNA results in increased susceptibility to Vincristine CTD PMID:25199881 NCBI chr  X:131,868,986...132,236,824
Ensembl chr  X:131,868,990...132,236,798 		JBrowse link
G Gpd2 glycerol-3-phosphate dehydrogenase 2 decreases expression ISO Vincristine results in decreased expression of GPD2 mRNA CTD PMID:23649840 NCBI chr 3:41,800,552...41,937,729
Ensembl chr 3:41,801,930...41,936,901 		JBrowse link
G Gpnmb glycoprotein nmb increases expression ISO Vincristine results in increased expression of GPNMB mRNA CTD PMID:23649840 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367 		JBrowse link
G Gpr132 G protein-coupled receptor 132 increases expression ISO Vincristine results in increased expression of GPR132 mRNA CTD PMID:23649840 NCBI chr 6:131,924,061...131,943,327
Ensembl chr 6:131,924,160...131,942,168 		JBrowse link
G Gpr137b G protein-coupled receptor 137B increases expression ISO Vincristine results in increased expression of GPR137B mRNA CTD PMID:23649840 NCBI chr17:86,003,635...86,041,841
Ensembl chr17:85,966,921...86,041,835 		JBrowse link
G Gpr180 G protein-coupled receptor 180 decreases expression ISO Vincristine results in decreased expression of GPR180 mRNA CTD PMID:23649840 NCBI chr15:95,195,782...95,224,955
Ensembl chr15:95,199,777...95,228,373 		JBrowse link
G Gpr55 G protein-coupled receptor 55 increases expression ISO Vincristine results in increased expression of GPR55 mRNA CTD PMID:23649840 NCBI chr 9:86,584,906...86,640,601
Ensembl chr 9:86,590,885...86,640,613 		JBrowse link
G Gpr63 G protein-coupled receptor 63 decreases expression ISO Vincristine results in decreased expression of GPR63 mRNA CTD PMID:23649840 NCBI chr 5:38,672,548...38,727,224
Ensembl chr 5:38,635,472...38,727,677 		JBrowse link
G Gpr84 G protein-coupled receptor 84 increases expression ISO Vincristine results in increased expression of GPR84 mRNA CTD PMID:23649840 NCBI chr 7:134,443,904...134,446,173
Ensembl chr 7:134,443,936...134,446,178 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases activity		 EXP Quercetin inhibits the reaction [Vincristine results in increased activity of GPT protein] CTD PMID:36808657 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gramd2b GRAM domain containing 2B increases expression ISO Vincristine results in increased expression of GRAMD2B mRNA CTD PMID:23649840 NCBI chr18:49,884,014...49,981,955
Ensembl chr18:49,884,014...49,981,953 		JBrowse link
G Grap2 GRB2-related adaptor protein 2 decreases expression ISO Vincristine results in decreased expression of GRAP2 mRNA CTD PMID:23649840 NCBI chr 7:112,117,142...112,190,880
Ensembl chr 7:112,117,142...112,190,877 		JBrowse link
G Gspt1 G1 to S phase transition 1 increases expression ISO Vincristine results in increased expression of GSPT1 mRNA CTD PMID:23649840 NCBI chr10:4,362,528...4,397,215
Ensembl chr10:4,362,510...4,397,198 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 affects response to substance
decreases response to substance
multiple interactions		 ISO GSTM1 gene polymorphism affects the susceptibility to Vincristine
GSTM1 protein results in decreased susceptibility to Vincristine
Sulfinpyrazone inhibits the reaction [GSTM1 protein results in decreased susceptibility to Vincristine]		 CTD PMID:15044619 PMID:15713801 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases response to substance
multiple interactions		 ISO GSTP1 protein results in decreased susceptibility to Vincristine
GSTP1 protein promotes the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]		 CTD PMID:10900222 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Gtf3c3 general transcription factor IIIC subunit 3 increases expression ISO Vincristine results in increased expression of GTF3C3 mRNA CTD PMID:23649840 NCBI chr 9:55,882,252...55,943,037
Ensembl chr 9:55,883,721...55,942,967 		JBrowse link
G Gtpbp3 GTP binding protein 3 decreases expression ISO Vincristine results in decreased expression of GTPBP3 mRNA CTD PMID:23649840 NCBI chr16:18,175,766...18,180,857
Ensembl chr16:18,175,766...18,180,857 		JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO [CEP 33779 results in increased susceptibility to Vincristine] which results in increased phosphorylation of H2AX protein; [NVP-BSK805 results in increased susceptibility to Vincristine] which results in increased phosphorylation of H2AX protein CTD PMID:28669723 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G H2bc12 H2B clustered histone 12 increases expression ISO Vincristine results in increased expression of H2BC12 mRNA CTD PMID:23649840 NCBI chr17:42,485,699...42,486,162 JBrowse link
G H2bc3 H2B clustered histone 3 increases expression ISO Vincristine results in increased expression of H2BC3 mRNA CTD PMID:23649840 NCBI chr17:41,380,056...41,380,686 JBrowse link
G H2bc6 H2B clustered histone 6 increases expression ISO Vincristine results in increased expression of H2BC6 mRNA CTD PMID:23649840 NCBI chr17:41,520,775...41,521,238 JBrowse link
G Hamp hepcidin antimicrobial peptide decreases expression ISO Vincristine results in decreased expression of HAMP mRNA CTD PMID:25633564 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891 		JBrowse link
G Haus2 HAUS augmin like complex subunit 2 decreases expression ISO Vincristine results in decreased expression of HAUS2 mRNA CTD PMID:23649840 NCBI chr 3:107,553,146...107,565,982
Ensembl chr 3:107,553,161...107,565,157 		JBrowse link
G Hbb hemoglobin subunit beta decreases expression ISO Vincristine results in decreased expression of HBB mRNA CTD PMID:23649840 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Hbb-b1 hemoglobin, beta adult major chain decreases expression ISO Vincristine results in decreased expression of HBD mRNA CTD PMID:23649840 NCBI chr 1:158,224,175...158,231,675
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Hdac1 histone deacetylase 1 decreases expression EXP Vincristine results in decreased expression of HDAC1 protein CTD PMID:27474498 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111 		JBrowse link
G Hdac4 histone deacetylase 4 decreases expression EXP Vincristine results in decreased expression of HDAC4 protein CTD PMID:27474498 NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164 		JBrowse link
G Hdac9 histone deacetylase 9 decreases expression ISO Vincristine results in decreased expression of HDAC9 mRNA CTD PMID:23649840 NCBI chr 6:50,762,074...51,624,311
Ensembl chr 6:50,763,590...51,625,333 		JBrowse link
G Hdhd3 haloacid dehalogenase-like hydrolase domain containing 3 decreases expression ISO Vincristine results in decreased expression of HDHD3 mRNA CTD PMID:23649840 NCBI chr 5:75,951,308...75,954,775
Ensembl chr 5:75,946,013...75,955,266 		JBrowse link
G Hectd4 HECT domain E3 ubiquitin protein ligase 4 increases expression ISO Vincristine results in increased expression of HECTD4 mRNA CTD PMID:23649840 NCBI chr12:35,182,165...35,330,935
Ensembl chr12:35,182,154...35,330,987 		JBrowse link
G Hells helicase, lymphoid specific decreases expression ISO Vincristine results in decreased expression of HELLS mRNA CTD PMID:23649840 NCBI chr 1:236,701,704...236,748,239
Ensembl chr 1:236,701,758...236,746,844 		JBrowse link
G Heph hephaestin increases expression ISO Vincristine results in increased expression of HEPH mRNA CTD PMID:23649840 NCBI chr  X:61,151,131...61,402,980
Ensembl chr  X:61,296,345...61,402,980 		JBrowse link
G Hhat hedgehog acyltransferase increases expression ISO Vincristine results in increased expression of HHAT mRNA CTD PMID:23649840 NCBI chr13:104,024,507...104,283,580
Ensembl chr13:104,010,916...104,282,893 		JBrowse link
G Hic1 HIC ZBTB transcriptional repressor 1 decreases expression ISO Vincristine results in decreased expression of HIC1 mRNA CTD PMID:23649840 NCBI chr10:60,014,520...60,019,475
Ensembl chr10:60,011,528...60,019,475 		JBrowse link
G Hilpda hypoxia inducible lipid droplet-associated decreases expression ISO Vincristine results in decreased expression of HILPDA mRNA CTD PMID:23649840 NCBI chr 4:57,871,088...57,874,048
Ensembl chr 4:57,871,110...57,874,557 		JBrowse link
G Hint1 histidine triad nucleotide binding protein 1 decreases expression ISO Vincristine results in decreased expression of HINT1 mRNA CTD PMID:23649840 NCBI chr10:38,989,516...38,993,259
Ensembl chr 4:92,100,973...92,101,568 		JBrowse link
G Hint3 histidine triad nucleotide binding protein 3 increases expression ISO Vincristine results in increased expression of HINT3 mRNA CTD PMID:23649840 NCBI chr 1:27,035,936...27,045,799
Ensembl chr 1:27,035,905...27,047,721 		JBrowse link
G Hist1h2al1 histone cluster 1 H2A family like 1 increases expression ISO Vincristine results in increased expression of H2AC6 mRNA CTD PMID:23649840 NCBI chr17:42,707,954...42,708,420 JBrowse link
G Hist1h2bc histone cluster 1, H2bc increases expression ISO Vincristine results in increased expression of H2BC21 mRNA CTD PMID:23649840 NCBI chr17:42,692,335...42,696,601
Ensembl chr17:42,694,723...42,696,642 		JBrowse link
G Hist1h2bd histone cluster 1 H2B family member D increases expression ISO Vincristine results in increased expression of H2BC5 mRNA CTD PMID:23649840 NCBI chr17:42,792,887...42,793,268 JBrowse link
G Hist1h2bq histone cluster 1 H2B family member Q increases expression ISO Vincristine results in increased expression of H2BC7 mRNA CTD PMID:23649840 NCBI chr17:41,432,100...41,441,487
Ensembl chr17:41,429,164...41,442,153 		JBrowse link
G Hivep3 HIVEP zinc finger 3 increases expression ISO Vincristine results in increased expression of HIVEP3 mRNA CTD PMID:23649840 NCBI chr 5:133,325,327...133,727,797
Ensembl chr 5:133,658,052...133,727,795 		JBrowse link
G Hlf HLF transcription factor, PAR bZIP family member increases expression ISO Vincristine results in increased expression of HLF mRNA CTD PMID:23649840 NCBI chr10:75,154,244...75,211,884
Ensembl chr10:75,154,507...75,211,935 		JBrowse link
G Hmcn1 hemicentin 1 increases response to substance ISO HMCN1 mRNA results in increased susceptibility to Vincristine CTD PMID:25199881 NCBI chr13:62,615,461...63,084,524
Ensembl chr13:62,615,461...63,084,524 		JBrowse link
G Hmga2 high mobility group AT-hook 2 decreases expression ISO Vincristine results in decreased expression of HMGA2 mRNA CTD PMID:23649840 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784 		JBrowse link
G Hmgb1 high mobility group box 1 decreases expression
increases secretion
decreases response to substance		 EXP
ISO		 Vincristine results in decreased expression of HMGB1 protein
Vincristine results in increased secretion of HMGB1 protein
HMGB1 protein results in decreased susceptibility to Vincristine		 CTD PMID:27474498 PMID:27807322 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hmgn5 high mobility group nucleosome binding domain 5 decreases expression ISO Vincristine results in decreased expression of HMGN5 mRNA CTD PMID:23649840 NCBI chr  X:74,085,871...74,094,488
Ensembl chr  X:74,085,875...74,094,441 		JBrowse link
G Hmox1 heme oxygenase 1 decreases expression
decreases activity
multiple interactions
increases expression		 ISO
EXP		 Vincristine results in decreased expression of HMOX1 mRNA
Vincristine results in decreased expression of HMOX1 protein
Vincristine results in decreased activity of HMOX1 protein
Quercetin inhibits the reaction [Vincristine results in decreased activity of HMOX1 protein]; Quercetin inhibits the reaction [Vincristine results in decreased expression of HMOX1 protein]
Vincristine results in increased expression of HMOX1 mRNA		 CTD PMID:20624997 PMID:23649840 PMID:33038355 PMID:36808657 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 decreases expression ISO Vincristine results in decreased expression of HNRNPA2B1 mRNA CTD PMID:23649840 NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249 		JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D decreases expression ISO Vincristine results in decreased expression of HNRNPD mRNA CTD PMID:23649840 NCBI chr14:9,615,375...9,638,975
Ensembl chr14:9,615,479...9,633,786 		JBrowse link
G Hnrnpdl heterogeneous nuclear ribonucleoprotein D-like decreases expression ISO Vincristine results in decreased expression of HNRNPDL mRNA CTD PMID:23649840 NCBI chr14:9,557,430...9,563,659
Ensembl chr14:9,557,425...9,562,506 		JBrowse link
G Hnrnpr heterogeneous nuclear ribonucleoprotein R decreases expression ISO Vincristine results in decreased expression of HNRNPR mRNA CTD PMID:23649840 NCBI chr 5:148,542,999...148,574,888
Ensembl chr 5:148,543,044...148,574,867 		JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U decreases expression ISO Vincristine results in decreased expression of HNRNPU mRNA CTD PMID:23649840 NCBI chr13:90,069,058...90,086,905
Ensembl chr13:90,074,181...90,086,588 		JBrowse link
G Hook1 hook microtubule-tethering protein 1 decreases expression ISO Vincristine results in decreased expression of HOOK1 mRNA CTD PMID:23649840 NCBI chr 5:110,824,501...110,887,791
Ensembl chr 5:110,824,501...110,887,787 		JBrowse link
G Hook3 hook microtubule-tethering protein 3 decreases expression ISO Vincristine results in decreased expression of HOOK3 mRNA CTD PMID:23649840 NCBI chr16:65,954,293...66,058,812
Ensembl chr16:65,954,350...66,061,338 		JBrowse link
G Hoxb7 homeo box B7 decreases expression ISO Vincristine results in decreased expression of HOXB7 mRNA CTD PMID:23649840 NCBI chr10:81,252,616...81,256,034
Ensembl chr10:81,252,553...81,256,034 		JBrowse link
G Hpdl 4-hydroxyphenylpyruvate dioxygenase-like decreases expression ISO Vincristine results in decreased expression of HPDL mRNA CTD PMID:23649840 NCBI chr 5:130,286,627...130,288,233
Ensembl chr 5:130,286,631...130,288,233 		JBrowse link
G Hras HRas proto-oncogene, GTPase increases expression ISO Vincristine results in increased expression of HRAS mRNA CTD PMID:16001973 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Hs2st1 heparan sulfate 2-O-sulfotransferase 1 decreases expression ISO Vincristine results in decreased expression of HS2ST1 mRNA CTD PMID:23649840 NCBI chr 2:233,508,018...233,641,769
Ensembl chr 2:233,508,021...233,641,769 		JBrowse link
G Hspa14 heat shock protein family A (Hsp70) member 14 decreases expression ISO Vincristine results in decreased expression of HSPA14 mRNA CTD PMID:23649840 NCBI chr17:74,728,945...74,749,727
Ensembl chr17:74,728,899...74,749,727 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions		 EXP Vincristine results in increased expression of HSPA5 mRNA
Quercetin inhibits the reaction [Vincristine results in increased expression of HSPA5 mRNA]		 CTD PMID:33038355 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Hspb2 heat shock protein family B (small) member 2 decreases response to substance ISO HSPB2 protein results in decreased susceptibility to Vincristine CTD PMID:17524270 NCBI chr 8:51,093,267...51,094,528
Ensembl chr 8:51,081,342...51,094,533 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 decreases expression ISO Vincristine results in decreased expression of HSPD1 mRNA CTD PMID:23649840 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662