water-soluble vitamin (role) - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	water-soluble vitamin (role)	go back to main search page
Accession:	CHEBI:27314	browse the term
Definition:	Any vitamin that dissolves in water and readily absorbed into tissues for immediate use. Unlike the fat-soluble vitamins, they are not stored in the body and need to be replenished regularly in the diet and will rarely accumulate to toxic levels since they are quickly excreted from the body via urine.
Synonyms:	related_synonym:	wasserloesliche Vitamine; water-soluble vitamin; water-soluble vitamins

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Genes (9750)

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

acetyl-CoA carboxylase alpha

decreases expression

EXP

Carnitine results in decreased expression of ACACA protein

NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,511,857...69,773,888

G

acetyl-CoA carboxylase beta

decreases expression

EXP

Carnitine results in decreased expression of ACACB protein

NCBI chr12:48,026,394...48,138,214
Ensembl chr12:48,026,394...48,138,214

G

adiponectin, C1Q and collagen domain containing

increases expression

EXP

Carnitine results in increased expression of ADIPOQ protein

NCBI chr11:91,226,524...91,240,244
Ensembl chr11:91,226,180...91,240,169

G

AKT serine/threonine kinase 1

multiple interactions
increases phosphorylation

EXP

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Carnitine results in increased phosphorylation of AKT1 protein]

NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610

G

amyloid beta precursor protein

multiple interactions

ISO

Carnitine promotes the reaction [Paraquat deficiency inhibits the reaction [Paraquat promotes the reaction [APP protein binds to APP protein]]]

NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971

G

BCL2 associated X, apoptosis regulator

decreases expression
multiple interactions

EXP

Carnitine results in decreased expression of BAX protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Carnitine results in decreased expression of BAX protein]; Carnitine inhibits the reaction [Atrazine results in increased expression of BAX mRNA]; Carnitine inhibits the reaction [Methotrexate results in increased expression of BAX protein]

PMID:29186614 PMID:36282381 PMID:37312617

NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429

G

gamma-butyrobetaine hydroxylase 1

multiple interactions
increases chemical synthesis

ISO

Aluminum inhibits the reaction [BBOX1 protein results in increased chemical synthesis of Carnitine]; Hydrogen Peroxide inhibits the reaction [BBOX1 protein results in increased chemical synthesis of Carnitine]; Ketoglutaric Acids inhibits the reaction [Aluminum inhibits the reaction [BBOX1 protein results in increased chemical synthesis of Carnitine]]; Ketoglutaric Acids inhibits the reaction [Hydrogen Peroxide inhibits the reaction [BBOX1 protein results in increased chemical synthesis of Carnitine]]

NCBI chr 3:117,277,226...117,326,383
Ensembl chr 3:117,277,226...117,326,064

G

BCL2, apoptosis regulator

multiple interactions
increases phosphorylation

EXP

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Carnitine results in increased phosphorylation of BCL2 protein]; Carnitine inhibits the reaction [Atrazine results in decreased expression of BCL2 mRNA]; Carnitine inhibits the reaction [Ifosfamide results in decreased expression of BCL2 mRNA]; Carnitine inhibits the reaction [Methotrexate results in decreased expression of BCL2 protein]

PMID:23213347 PMID:29186614 PMID:36282381 PMID:37312617

NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900

G

Bcl2-like 1

multiple interactions

EXP

Carnitine inhibits the reaction [Gentamicins results in decreased expression of BCL2L1 protein]

NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907

G

caspase 3

multiple interactions
increases expression

EXP
ISO

Carnitine inhibits the reaction [Atrazine results in increased expression of CASP3 mRNA]; Carnitine inhibits the reaction [Gentamicins results in increased cleavage of CASP3 protein]; Carnitine inhibits the reaction [Ifosfamide results in increased expression of CASP3 mRNA]; Carnitine inhibits the reaction [Iohexol promotes the reaction [Glycerol results in increased expression of CASP3 mRNA]]; Carnitine inhibits the reaction [Methotrexate results in increased expression of CASP3 protein]
Carnitine results in increased expression of CASP3 protein
Carnitine inhibits the reaction [quinone results in increased activity of CASP3 protein]

PMID:19491382 PMID:23213347 PMID:25669660 PMID:26562095 PMID:32478940 More...

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732

G

caspase 8

multiple interactions

ISO

Carnitine inhibits the reaction [quinone results in increased activity of CASP8 protein]

NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699

G

caspase 9

multiple interactions

EXP
ISO

Carnitine inhibits the reaction [Ifosfamide results in increased expression of CASP9 mRNA]
Carnitine inhibits the reaction [quinone results in increased activity of CASP9 protein]

PMID:23213347 PMID:32478940

Ensembl chr 5:159,391,188...159,409,648

G

catalase

multiple interactions

EXP

Carnitine inhibits the reaction [Diethylnitrosamine results in decreased activity of CAT protein]; Carnitine inhibits the reaction [Doxorubicin results in decreased activity of CAT protein]; Carnitine inhibits the reaction [Ifosfamide results in decreased expression of CAT mRNA]

PMID:16889571 PMID:19294768 PMID:23213347

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526

G

cellular communication network factor 2

multiple interactions

EXP

Carnitine inhibits the reaction [Sunitinib results in increased expression of CCN2 mRNA]

NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:22,621,501...22,624,976

G

cadherin 1

multiple interactions

EXP

Carnitine inhibits the reaction [perfluorooctane sulfonic acid results in decreased expression of CDH1 protein]

NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565

G

collagen type I alpha 1 chain

multiple interactions

EXP

Carnitine inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of COL1A1 mRNA]; Carnitine inhibits the reaction [Sunitinib results in increased expression of COL1A1 mRNA]

PMID:26581635 PMID:28973641

NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460

G

collagen type II alpha 1 chain

multiple interactions

EXP

[COL2A1 protein co-treated with Freund's Adjuvant] affects the abundance of Carnitine; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Carnitine]; Dexamethasone inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Carnitine]; huang-lien-chieh-tu-tang inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Carnitine]

NCBI chr 7:130,977,561...131,006,627
Ensembl chr 7:130,977,561...131,006,627

G

carnitine palmitoyltransferase 1A

multiple interactions

EXP
ISO

valproyl-coenzyme A inhibits the reaction [CPT1A protein results in increased metabolism of Carnitine]
[Doxorubicin co-treated with Carnitine] results in increased expression of CPT1A mRNA; [Genistein co-treated with Carnitine] results in increased expression of CPT1A protein; Carnitine inhibits the reaction [quinone results in decreased expression of CPT1A protein]

PMID:16283381 PMID:16362726 PMID:19854160 PMID:32478940

NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:209,993,875...210,056,326

G

carnitine palmitoyltransferase 2

multiple interactions
increases expression

ISO
EXP

Carnitine promotes the reaction [[Bezafibrate results in increased activity of CPT2 protein] which results in increased abundance of Adenosine Triphosphate]
Carnitine results in increased expression of CPT2 protein

PMID:21816645 PMID:25669660

NCBI chr 5:127,893,450...127,911,347
Ensembl chr 5:127,893,207...127,910,818

G

cytochrome b-245 beta chain

multiple interactions

EXP

Carnitine inhibits the reaction [Sunitinib results in increased expression of CYBB mRNA]; Carnitine inhibits the reaction [Sunitinib results in increased expression of CYBB protein]

NCBI chr X:16,030,596...16,065,065
Ensembl chr X:16,030,596...16,065,065

G

cytochrome P450, family 17, subfamily a, polypeptide 1

multiple interactions

EXP

Carnitine inhibits the reaction [Atrazine results in decreased expression of CYP17A1 mRNA]

NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974

G

cytochrome P450, family 2, subfamily e, polypeptide 1

multiple interactions

EXP

Carnitine promotes the reaction [Ethanol results in increased expression of CYP2E1 protein]

NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495

G

fatty acid binding protein 3

multiple interactions

EXP

Carnitine inhibits the reaction [Doxorubicin results in decreased expression of FABP3 mRNA]

NCBI chr 5:147,936,027...147,942,870
Ensembl chr 5:147,936,119...147,942,881

G

fatty acid binding protein 9

multiple interactions

EXP

Carnitine inhibits the reaction [carbendazim results in decreased expression of FABP9 mRNA]; Carnitine inhibits the reaction [carbendazim results in decreased expression of FABP9 protein]

NCBI chr 2:93,499,136...93,503,267
Ensembl chr 2:93,499,134...93,503,260

G

fatty acid synthase

decreases expression

EXP

Carnitine results in decreased expression of FASN protein

NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583

G

follicle stimulating hormone subunit beta

multiple interactions

EXP

Carnitine inhibits the reaction [carbendazim results in decreased expression of FSHB protein]

NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:114,003,262...114,007,072

G

growth differentiation factor 9

multiple interactions
increases expression

ISO

Carnitine inhibits the reaction [Cyclophosphamide results in decreased expression of GDF9 mRNA]
Carnitine results in increased expression of GDF9 mRNA

NCBI chr10:38,090,021...38,100,801
Ensembl chr10:38,089,878...38,100,797

G

glial fibrillary acidic protein

multiple interactions

EXP

Carnitine inhibits the reaction [Atrazine results in increased expression of GFAP protein]

NCBI chr10:88,352,987...88,361,661
Ensembl chr10:88,352,986...88,361,685

G

gap junction protein, alpha 1

multiple interactions
increases expression

ISO

Carnitine inhibits the reaction [Cyclophosphamide results in decreased expression of GJA1 mRNA]
Carnitine results in increased expression of GJA1 mRNA

NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689

G

gap junction protein, alpha 4

increases expression
multiple interactions

ISO

Carnitine results in increased expression of GJA4 mRNA
Carnitine inhibits the reaction [Cyclophosphamide results in decreased expression of GJA4 mRNA]

NCBI chr 5:144,917,791...144,920,324
Ensembl chr 5:144,914,147...144,921,216

G

glutamic--pyruvic transaminase

multiple interactions

EXP

Carnitine inhibits the reaction [Atrazine results in increased activity of GPT protein]

NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160

G

glutathione peroxidase 1

multiple interactions

EXP

Carnitine inhibits the reaction [Ifosfamide results in decreased expression of GPX1 mRNA]

NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581

G

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha

multiple interactions

ISO

Carnitine inhibits the reaction [quinone results in decreased expression of HADHA protein]

NCBI chr 6:31,907,801...31,947,434
Ensembl chr 6:31,907,291...31,947,698

G

hyaluronan synthase 2

multiple interactions
increases expression

ISO

Carnitine inhibits the reaction [Cyclophosphamide results in decreased expression of HAS2 mRNA]
Carnitine results in increased expression of HAS2 mRNA

NCBI chr 7:90,002,929...90,028,933
Ensembl chr 7:90,002,929...90,018,535

G

heme oxygenase 1

multiple interactions

EXP

Carnitine inhibits the reaction [Methotrexate results in decreased expression of HMOX1 protein]

NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818

G

harakiri, BCL2 interacting protein

multiple interactions

ISO

Carnitine inhibits the reaction [Gentamicins results in increased expression of HRK mRNA]; Carnitine inhibits the reaction [Gentamicins results in increased expression of HRK protein]

NCBI chr12:44,048,402...44,070,561
Ensembl chr12:44,048,402...44,070,561

G

heat shock protein family A (Hsp70) member 2

multiple interactions

EXP

Carnitine inhibits the reaction [Cadmium Chloride results in increased expression of HSPA2 protein]

NCBI chr 6:100,864,172...100,866,946
Ensembl chr 6:100,864,553...100,867,133

G

isocitrate dehydrogenase (NADP(+)) 2

multiple interactions
increases abundance

ISO

Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Carnitine]

NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:143,439,323...143,467,248

G

interleukin 10

multiple interactions

EXP

Carnitine inhibits the reaction [carbendazim results in decreased expression of IL10 protein]; Carnitine inhibits the reaction [Sunitinib results in decreased expression of IL10 mRNA]

PMID:26581635 PMID:33965443

NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580

G

interleukin 18

increases expression

EXP

Carnitine results in increased expression of IL18 protein

NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286

G

interleukin 1 beta

multiple interactions
increases expression

EXP

Carnitine inhibits the reaction [Iohexol promotes the reaction [Glycerol results in increased expression of IL1B mRNA]]; Carnitine inhibits the reaction [sunitinib results in increased expression of IL1B mRNA]
Carnitine results in increased expression of IL1B protein

PMID:25669660 PMID:26562095 PMID:26581635

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601

G

interleukin 6

multiple interactions

EXP

Carnitine inhibits the reaction [carbendazim results in increased expression of IL6 protein]; Carnitine inhibits the reaction [Methotrexate results in increased expression of IL6 protein]; Carnitine inhibits the reaction [Sunitinib results in increased expression of IL6 mRNA]

PMID:26581635 PMID:33965443 PMID:37312617

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610

G

insulin 1

decreases uptake
multiple interactions

ISO
EXP

INS1 protein results in decreased uptake of Carnitine
Carnitine inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased secretion of INS1 protein]

PMID:28298333 PMID:30256492

NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682

G

lactate dehydrogenase A

multiple interactions

ISO

Carnitine inhibits the reaction [Doxorubicin results in increased activity of LDHA protein]

NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521

G

leptin receptor

affects abundance

ISO

LEPR affects the abundance of Carnitine

NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215

G

luteinizing hormone subunit beta

multiple interactions

EXP

Carnitine inhibits the reaction [carbendazim results in decreased expression of LHB protein]

NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445

G

matrix metallopeptidase 9

multiple interactions

EXP

Carnitine inhibits the reaction [sunitinib results in decreased expression of MMP9 mRNA]

NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442

G

myeloperoxidase

multiple interactions
increases activity

EXP

[Carboplatin co-treated with Carnitine deficiency] results in increased expression of MPO protein; Acetaminophen promotes the reaction [Carnitine deficiency results in increased activity of MPO protein]

PMID:18597074 PMID:18852009

NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056

G

mitochondrially encoded cytochrome c oxidase I

multiple interactions

ISO

Carnitine inhibits the reaction [nickel chloride results in decreased expression of COX1 mRNA]

NCBI chr MT:5,323...6,867
Ensembl chr MT:5,309...6,853

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6

multiple interactions

ISO

Carnitine inhibits the reaction [nickel chloride results in decreased expression of ND6 mRNA]

NCBI chr MT:13,543...14,061
Ensembl chr MT:13,531...14,049

G

microsomal triglyceride transfer protein

multiple interactions

EXP

Carnitine inhibits the reaction [Stavudine results in decreased expression of MTTP mRNA]

NCBI chr 2:229,286,501...229,327,650
Ensembl chr 2:229,286,501...229,327,650

G

NFE2 like bZIP transcription factor 2

multiple interactions

EXP

Carnitine inhibits the reaction [Methotrexate results in decreased expression of NFE2L2 protein]

NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090

G

NLR family, pyrin domain containing 3

increases expression

EXP

Carnitine results in increased expression of NLRP3 protein

NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394

G

nitric oxide synthase 2

multiple interactions

EXP

Carnitine inhibits the reaction [carbendazim results in increased expression of NOS2 protein]; Carnitine inhibits the reaction [Ifosfamide results in increased expression of NOS2 mRNA]

PMID:23213347 PMID:33965443

NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880

G

nitric oxide synthase 3

increases expression

EXP

Carnitine results in increased expression of NOS3

NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664

G

occludin

multiple interactions

EXP

Carnitine inhibits the reaction [carbendazim results in decreased expression of OCLN protein]

NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:33,391,303...33,430,411

G

peroxisome proliferator activated receptor alpha

multiple interactions
increases expression
increases activity

EXP

[pirinixic acid results in increased activity of PPARA protein] promotes the reaction [SLC22A21 protein results in increased uptake of Carnitine]; PPARA protein promotes the reaction [Carnitine results in decreased susceptibility to Gentamicins]
Carnitine results in increased expression of PPARA protein
Carnitine results in increased activity of PPARA protein

PMID:19491382 PMID:19735737 PMID:25669660

NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714

G

peroxisome proliferator-activated receptor gamma

increases expression
multiple interactions

EXP

Carnitine results in increased expression of PPARG protein
Carnitine inhibits the reaction [[Dietary Fats co-treated with Fructose] results in decreased expression of PPARG protein]

NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104

G

PPARG coactivator 1 alpha

multiple interactions

EXP

Carnitine inhibits the reaction [Methotrexate results in decreased expression of PPARGC1A protein]

NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213

G

prostaglandin I2 synthase

increases expression
increases response to substance
multiple interactions

EXP

Carnitine results in increased expression of PTGIS mRNA
PTGIS protein results in increased susceptibility to Carnitine
[Carnitine results in increased expression of PTGIS mRNA] which results in increased chemical synthesis of 6-Ketoprostaglandin F1 alpha

NCBI chr 3:176,347,589...176,383,251
Ensembl chr 3:176,335,437...176,407,650

G

PYD and CARD domain containing

increases expression

EXP

Carnitine results in increased expression of PYCARD protein

NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:192,032,124...192,033,419

G

RELA proto-oncogene, NF-kB subunit

multiple interactions

EXP

Carnitine inhibits the reaction [carbendazim results in increased expression of RELA protein]

NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817

G

stearoyl-CoA desaturase

decreases expression

EXP

Carnitine results in decreased expression of SCD protein

NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:253,218,970...253,231,785

G

sirtuin 1

multiple interactions

EXP

Carnitine inhibits the reaction [Methotrexate results in decreased expression of SIRT1 protein]

NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000

G

sirtuin 3

multiple interactions

ISO

Carnitine inhibits the reaction [Cyclophosphamide results in increased expression of SIRT3 mRNA]

NCBI chr 1:205,371,703...205,394,145
Ensembl chr 1:205,371,710...205,394,076

G

solute carrier family 22 member 1

decreases expression

EXP

Carnitine results in decreased expression of SLC22A1 protein

NCBI chr 1:50,624,339...50,651,437
Ensembl chr 1:50,624,377...50,651,436

G

solute carrier family 22 member 2

decreases expression

EXP

Carnitine results in decreased expression of SLC22A2 protein

NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019

G

solute carrier family 22 (organic cation transporter), member 21

multiple interactions
increases uptake

EXP

[pirinixic acid results in increased activity of PPARA protein] promotes the reaction [SLC22A21 protein results in increased uptake of Carnitine]

NCBI chr10:38,605,665...38,633,376
Ensembl chr10:38,604,886...38,631,209

G

solute carrier family 22 member 4

increases uptake
decreases expression

ISO
EXP

SLC22A4 protein results in increased uptake of Carnitine
Carnitine results in decreased expression of SLC22A4 protein

PMID:21256917 PMID:25669660 PMID:33007874

NCBI chr10:38,634,098...38,687,409
Ensembl chr10:38,634,098...38,679,920

G

solute carrier family 22 member 5

multiple interactions
affects expression
decreases expression
increases transport
increases uptake
increases expression
affects uptake
affects binding

ISO
EXP

[Doxorubicin co-treated with Carnitine] results in increased expression of SLC22A5 mRNA; Amiodarone inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Atorvastatin inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Betaine inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Carnitine inhibits the reaction [SLC22A5 protein results in increased abundance of Doxorubicin]; Carnitine inhibits the reaction [SLC22A5 protein results in increased transport of pivaloylcarnitine]; Choline inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Clozapine inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; grepafloxacin affects the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Ipratropium inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Lidocaine inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Nifedipine inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Ofloxacin inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Olanzapine inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine analog]; pivaloylcarnitine inhibits the reaction [SLC22A5 protein results in increased transport of Carnitine]; Propranolol inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Quetiapine Fumarate inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Spironolactone inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; talinolol inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; ziprasidone inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]
Carnitine affects the expression of SLC22A5 protein
Carnitine inhibits the reaction [SLC22A5 protein results in increased abundance of and results in increased localization of Doxorubicin]
Carnitine results in decreased expression of SLC22A5 mRNA; Carnitine results in decreased expression of SLC22A5 protein
1-Methyl-4-phenylpyridinium inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Carnitine inhibits the reaction [Cyclophosphamide results in decreased expression of SLC22A5 mRNA]; Carnitine inhibits the reaction [Cyclophosphamide results in decreased expression of SLC22A5 protein]; Carnitine inhibits the reaction [Doxorubicin results in decreased expression of SLC22A5 mRNA]; Carnitine inhibits the reaction [SLC22A5 protein results in increased uptake of Tetraethylammonium]; Dithioerythritol inhibits the reaction [Omeprazole inhibits the reaction [SLC22A5 protein results in increased transport of Carnitine]]; Ofloxacin inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Omeprazole inhibits the reaction [SLC22A5 protein results in increased transport of Carnitine]; Tetraethylammonium inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]
Carnitine deficiency results in increased expression of SLC22A5 mRNA
SLC22A5 protein results in increased uptake of Carnitine; SLC22A5 protein results in increased uptake of Carnitine analog
SLC22A5 protein affects the uptake of Carnitine
Carnitine binds to SLC22A5 protein

PMID:12644265 PMID:15486076 PMID:16283381 PMID:16928358 PMID:18762717 More...

NCBI chr10:38,509,072...38,536,240
Ensembl chr10:38,509,072...38,536,077

G

solute carrier family 22 member 8

increases transport

ISO

SLC22A8 protein results in increased transport of Carnitine

NCBI chr 1:214,925,506...214,945,516
Ensembl chr 1:214,925,508...214,946,588

G

solute carrier family 25 member 20

multiple interactions
increases transport

EXP

Ampicillin inhibits the reaction [SLC25A20 protein results in increased transport of Carnitine]; Carnitine inhibits the reaction [Hydrogen Peroxide results in decreased activity of SLC25A20 protein]; Cefazolin inhibits the reaction [SLC25A20 protein results in increased transport of Carnitine]; Cefonicid inhibits the reaction [SLC25A20 protein results in increased transport of Carnitine]; Cephalothin inhibits the reaction [SLC25A20 protein results in increased transport of Carnitine]; Piperacillin inhibits the reaction [SLC25A20 protein results in increased transport of Carnitine]

PMID:18452908 PMID:23402788

NCBI chr 8:118,243,573...118,265,027
Ensembl chr 8:118,243,519...118,265,027

G

solute carrier family 2 member 4

increases expression
multiple interactions

EXP

Carnitine results in increased expression of SLC2A4 protein
Carnitine inhibits the reaction [[Dietary Fats co-treated with Fructose] results in decreased expression of SLC2A4 protein]

NCBI chr10:55,164,721...55,170,289
Ensembl chr10:55,164,721...55,170,270

G

snail family transcriptional repressor 1

multiple interactions

EXP

Carnitine inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of SNAI1 protein]

NCBI chr 3:176,667,476...176,671,965

G

sterol regulatory element binding transcription factor 1

multiple interactions
decreases expression

EXP

Carnitine inhibits the reaction [Stavudine results in increased expression of SREBF1 mRNA]
Carnitine results in decreased expression of SREBF1 protein

PMID:18299183 PMID:25669660

NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164

G

steroidogenic acute regulatory protein

multiple interactions

EXP

Carnitine inhibits the reaction [carbendazim results in decreased expression of STAR mRNA]; Carnitine inhibits the reaction [carbendazim results in decreased expression of STAR protein]

NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447

G

transforming growth factor, beta 1

multiple interactions

EXP

Carnitine inhibits the reaction [Iohexol promotes the reaction [Glycerol results in increased expression of TGFB1 mRNA]]; Carnitine inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of TGFB1 mRNA]; Carnitine inhibits the reaction [sunitinib results in increased expression of TGFB1 mRNA]

PMID:26562095 PMID:26581635 PMID:28973641

NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899

G

TIMP metallopeptidase inhibitor 1

multiple interactions

EXP

Carnitine inhibits the reaction [sunitinib results in increased expression of TIMP1 mRNA]

NCBI chr X:3,766,509...3,772,578
Ensembl chr X:3,766,510...3,771,135

G

tight junction protein 1

multiple interactions

EXP

Carnitine inhibits the reaction [perfluorooctane sulfonic acid results in decreased expression of TJP1 protein]

NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:128,260,330...128,505,158

G

tumor necrosis factor

increases expression
multiple interactions
decreases expression

EXP

Carnitine deficiency results in increased expression of TNF mRNA
[Carboplatin co-treated with Carnitine deficiency] results in increased expression of TNF protein; Acetaminophen promotes the reaction [Carnitine deficiency results in increased expression of TNF mRNA]; Carnitine inhibits the reaction [carbendazim results in increased expression of TNF protein]; Carnitine inhibits the reaction [Iohexol promotes the reaction [Glycerol results in increased expression of TNF mRNA]]; Carnitine inhibits the reaction [Iohexol promotes the reaction [Glycerol results in increased expression of TNF protein]]; Carnitine inhibits the reaction [Methotrexate results in increased expression of TNF protein]
Carnitine results in decreased expression of TNF protein

PMID:18597074 PMID:18629605 PMID:18852009 PMID:26562095 PMID:33965443 More...

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303

G

vimentin

multiple interactions

EXP

Carnitine inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of VIM protein]

NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746

(R)-pantothenic acid

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

atonal bHLH transcription factor 8

increases expression

ISO

Pantothenic Acid results in increased expression of ATOH8 mRNA

NCBI chr 4:105,818,203...105,850,379
Ensembl chr 4:105,818,203...105,850,379

G

cell death-inducing DFFA-like effector a

multiple interactions

ISO

[acetyl methyl tetramethyl tetralin co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in decreased expression of CIDEA mRNA

NCBI chr18:63,164,817...63,190,384
Ensembl chr18:63,164,099...63,190,382

G

cell death-inducing DFFA-like effector c

multiple interactions

ISO

[acetyl methyl tetramethyl tetralin co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in increased expression of CIDEC mRNA; [quinoxyfen co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in increased expression of CIDEC mRNA

NCBI chr 4:148,124,924...148,137,806
Ensembl chr 4:148,124,925...148,137,806

G

collagen type II alpha 1 chain

multiple interactions

EXP

[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of Pantothenic Acid; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of Pantothenic Acid]; Dexamethasone inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of Pantothenic Acid]; huang-lien-chieh-tu-tang inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of Pantothenic Acid]

NCBI chr 7:130,977,561...131,006,627
Ensembl chr 7:130,977,561...131,006,627

G

cytochrome P450, family 1, subfamily b, polypeptide 1

increases expression

ISO

Pantothenic Acid results in increased expression of CYP1B1 mRNA

NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142

G

family with sequence similarity 43, member A

increases expression

ISO

Pantothenic Acid results in increased expression of FAM43A mRNA

NCBI chr11:83,633,165...83,636,313
Ensembl chr11:83,633,154...83,695,297

G

fucosyltransferase 7

decreases expression

ISO

Pantothenic Acid results in decreased expression of FUT7 mRNA

NCBI chr 3:28,635,913...28,640,407
Ensembl chr 3:28,637,107...28,641,388

G

heme oxygenase 1

increases expression

ISO

Pantothenic Acid results in increased expression of HMOX1 mRNA; Pantothenic Acid results in increased expression of HMOX1 protein

NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818

G

heat shock protein family B (small) member 7

increases expression

ISO

Pantothenic Acid results in increased expression of HSPB7 mRNA

NCBI chr 5:159,010,759...159,014,245
Ensembl chr 5:159,010,629...159,014,243

G

inhibitor of DNA binding 1

increases expression

ISO

Pantothenic Acid results in increased expression of ID1 mRNA

NCBI chr 3:161,671,525...161,672,691
Ensembl chr 3:161,671,538...161,672,685

G

inhibitor of DNA binding 3

increases expression

ISO

Pantothenic Acid results in increased expression of ID3 mRNA

NCBI chr 5:153,656,253...153,657,860
Ensembl chr 5:153,630,498...153,657,856

G

isocitrate dehydrogenase (NADP(+)) 2

increases abundance
multiple interactions

ISO

IDH2 protein mutant form results in increased abundance of Pantothenic Acid
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Pantothenic Acid]

NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:143,439,323...143,467,248

G

interleukin 6

increases expression

ISO

Pantothenic Acid results in increased expression of IL6 mRNA

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610

G

insulin 1

multiple interactions

ISO

[acetyl methyl tetramethyl tetralin co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in decreased expression of CIDEA mRNA; [acetyl methyl tetramethyl tetralin co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in decreased expression of SDHA protein; [acetyl methyl tetramethyl tetralin co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in increased expression of CIDEC mRNA; [quinoxyfen co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in decreased expression of SDHA protein; [quinoxyfen co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in increased expression of CIDEC mRNA

NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682

G

leptin receptor

affects abundance

ISO

LEPR affects the abundance of Pantothenic Acid

NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215

G

membrane associated ring-CH-type finger 2

increases expression

ISO

Pantothenic Acid results in increased expression of MARCHF2 mRNA

NCBI chr 7:15,183,931...15,209,988
Ensembl chr 7:15,183,925...15,202,002

G

mitochondrial transcription rescue factor 1

increases expression

ISO

Pantothenic Acid results in increased expression of MTRES1 mRNA

NCBI chr20:48,604,479...48,622,364
Ensembl chr20:48,604,372...48,622,014

G

MYB proto-oncogene, transcription factor

multiple interactions

ISO

Pantothenic Acid inhibits the reaction [Valproic Acid results in decreased expression of MYB protein]

NCBI chr 1:17,759,309...17,793,306
Ensembl chr 1:17,759,309...17,792,547

G

MYCN proto-oncogene, bHLH transcription factor

increases expression

ISO

Pantothenic Acid results in increased expression of MYCN mRNA

NCBI chr 6:41,446,683...41,452,584
Ensembl chr 6:41,446,684...41,452,508

G

NHL repeat containing E3 ubiquitin protein ligase 1

increases expression

ISO

Pantothenic Acid results in increased expression of NHLRC1 mRNA

NCBI chr17:17,880,570...17,883,411
Ensembl chr17:17,880,365...17,883,620

G

nuclear receptor subfamily 4, group A, member 1

multiple interactions

ISO

[Glycerol co-treated with Succinic Acid co-treated with Glucose-6-Phosphate co-treated with Pantothenic Acid co-treated with Niacinamide] results in increased expression of NR4A1 mRNA

NCBI chr 7:134,247,153...134,268,044
Ensembl chr 7:134,247,192...134,268,041

G

neuronal regeneration related protein

increases expression

ISO

Pantothenic Acid results in increased expression of NREP mRNA

NCBI chr18:25,291,219...25,320,742
Ensembl chr18:25,291,219...25,320,742

G

Pim-1 proto-oncogene, serine/threonine kinase

multiple interactions

ISO

Pantothenic Acid inhibits the reaction [Valproic Acid results in decreased expression of PIM1 protein]

NCBI chr20:7,556,496...7,560,747
Ensembl chr20:7,556,113...7,561,764

G

POU class 3 homeobox 4

increases expression

ISO

Pantothenic Acid results in increased expression of POU3F4 mRNA

NCBI chr X:79,974,808...79,976,085
Ensembl chr X:79,974,627...79,987,326

G

protein tyrosine phosphatase, receptor type, C-associated protein

increases expression

ISO

Pantothenic Acid results in increased expression of PTPRCAP mRNA

NCBI chr 1:210,878,593...210,880,752
Ensembl chr 1:210,878,573...210,881,753

G

succinate dehydrogenase complex flavoprotein subunit A

multiple interactions

ISO

[acetyl methyl tetramethyl tetralin co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in decreased expression of SDHA protein; [quinoxyfen co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in decreased expression of SDHA protein

NCBI chr 1:30,764,553...30,789,523
Ensembl chr 1:30,764,590...30,790,121

G

SLC51 subunit beta

increases expression

ISO

Pantothenic Acid results in increased expression of SLC51B mRNA

NCBI chr 8:74,827,047...74,835,109
Ensembl chr 8:74,827,047...74,835,109

G

solute carrier family 5 member 6

increases transport
multiple interactions

EXP
ISO

SLC5A6 results in increased transport of Pantothenic Acid
Thioctic Acid inhibits the reaction [SLC5A6 results in increased transport of Pantothenic Acid]
Sodium affects the reaction [SLC5A6 results in increased transport of Pantothenic Acid]

PMID:9516450 PMID:10329687

NCBI chr 6:31,039,865...31,051,671
Ensembl chr 6:31,040,017...31,051,670

G

SRY-box transcription factor 2

decreases expression

ISO

Pantothenic Acid results in decreased expression of SOX2 mRNA

NCBI chr 2:119,465,131...119,467,542
Ensembl chr 2:119,454,541...119,496,350

G

transferrin

multiple interactions

ISO

[acetyl methyl tetramethyl tetralin co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in decreased expression of CIDEA mRNA; [acetyl methyl tetramethyl tetralin co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in decreased expression of SDHA protein; [acetyl methyl tetramethyl tetralin co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in increased expression of CIDEC mRNA; [quinoxyfen co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in decreased expression of SDHA protein; [quinoxyfen co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in increased expression of CIDEC mRNA

NCBI chr 8:112,668,667...112,695,376
Ensembl chr 8:112,647,642...112,695,400

G

transmembrane protein 18

increases expression

ISO

Pantothenic Acid results in increased expression of TMEM18 mRNA

NCBI chr 6:52,934,419...52,941,868
Ensembl chr 6:52,934,419...52,941,866

G

zinc finger protein 575

decreases expression

ISO

Pantothenic Acid results in decreased expression of ZNF575 mRNA

NCBI chr 1:89,302,927...89,305,087
Ensembl chr 1:89,302,904...89,305,187

10-formyltetrahydrofolic acid

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aldehyde dehydrogenase 1 family, member L2

increases metabolic processing

ISO

ALDH1L2 protein results in increased metabolism of 10-formyltetrahydropteroylglutamic acid

NCBI chr 7:22,141,872...22,193,403
Ensembl chr 7:22,141,842...22,193,398

4-pyridoxic acid

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

collagen type II alpha 1 chain

multiple interactions

EXP

[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of Pyridoxic Acid

NCBI chr 7:130,977,561...131,006,627
Ensembl chr 7:130,977,561...131,006,627

5,10-methylenetetrahydrofolic acid

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

methylenetetrahydrofolate reductase

increases metabolic processing
increases reduction

ISO

MTHFR protein results in increased metabolism of 5,10-methylenetetrahydrofolic acid
MTHFR protein results in increased reduction of 5,10-methylenetetrahydrofolic acid

PMID:7647779 PMID:16187112

NCBI chr 5:163,748,346...163,768,141
Ensembl chr 5:163,748,321...163,768,105

5,6,7,8-tetrahydrofolic acid

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aldehyde dehydrogenase 1 family, member L2

increases chemical synthesis

ISO

ALDH1L2 protein results in increased chemical synthesis of 5,6,7,8-tetrahydrofolic acid

NCBI chr 7:22,141,872...22,193,403
Ensembl chr 7:22,141,842...22,193,398

G

alkaline phosphatase, intestinal

multiple interactions

ISO

5,6,7,8-tetrahydrofolic acid inhibits the reaction [Methotrexate results in increased activity of ALPI protein]

NCBI chr 9:95,221,314...95,224,780
Ensembl chr 9:95,221,314...95,224,780

G

insulin-like growth factor 1 receptor

decreases expression

ISO

5,6,7,8-tetrahydrofolic acid results in decreased expression of IGF1R mRNA

NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:130,959,997...131,248,664

G

5-methyltetrahydrofolate-homocysteine methyltransferase

multiple interactions

ISO

5,6,7,8-tetrahydrofolic acid inhibits the reaction [Methotrexate results in decreased expression of MTR protein]; [Thymidine co-treated with Hypoxanthine co-treated with 5,6,7,8-tetrahydrofolic acid] inhibits the reaction [Methotrexate results in decreased expression of MTR protein]

NCBI chr17:62,911,705...62,996,544
Ensembl chr17:62,911,771...62,996,541

G

solute carrier family 19 member 1

multiple interactions
decreases activity

EXP

5,6,7,8-tetrahydrofolic acid inhibits the reaction [SLC19A1 protein affects the transport of Methotrexate]
5,6,7,8-tetrahydrofolic acid results in decreased activity of SLC19A1 protein

NCBI chr20:11,583,928...11,601,959
Ensembl chr20:11,583,929...11,601,488

G

thymidylate synthetase

increases activity

EXP

5,6,7,8-tetrahydrofolic acid results in increased activity of TYMS protein

NCBI chr 9:120,760,057...120,776,149
Ensembl chr 9:120,763,386...120,776,097

5-formyltetrahydrofolic acid

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily C member 2

multiple interactions

EXP

Leucovorin inhibits the reaction [Methotrexate results in decreased expression of ABCC2 protein]

NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471

G

albumin

multiple interactions

ISO

[Leucovorin co-treated with Cisplatin co-treated with Fluorouracil] results in decreased expression of ALB protein

NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865

G

angiopoietin-like 2

multiple interactions

ISO

ANGPTL2 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan]

NCBI chr 3:36,914,876...36,944,715
Ensembl chr 3:36,914,745...36,945,876

G

ARF like GTPase 6 interacting protein 5

multiple interactions

ISO

ARL6IP5 protein affects the susceptibility to [Fluorouracil co-treated with Leucovorin co-treated with Cisplatin]; ARL6IP5 protein affects the susceptibility to [Fluorouracil co-treated with Leucovorin co-treated with oxaliplatin]

NCBI chr 4:131,365,320...131,395,311
Ensembl chr 4:131,367,289...131,400,130

G

ATP synthase peripheral stalk subunit OSCP

multiple interactions

ISO

ATP5PO mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan]

NCBI chr11:44,651,171...44,657,483
Ensembl chr11:44,651,173...44,657,520

G

axin 2

multiple interactions

EXP

[Methotrexate co-treated with Leucovorin] results in increased expression of AXIN2 mRNA

NCBI chr10:94,393,379...94,426,579
Ensembl chr10:94,395,909...94,426,575

G

BCL6, transcription repressor

multiple interactions

ISO

Leucovorin inhibits the reaction [Pyrimethamine inhibits the reaction [Oncostatin M results in increased expression of BCL6 mRNA]]

NCBI chr11:90,358,753...90,382,049
Ensembl chr11:90,358,753...90,382,047

G

bone gamma-carboxyglutamate protein

multiple interactions

EXP

[Methotrexate co-treated with Leucovorin] results in increased expression of BGLAP mRNA

NCBI chr 2:176,136,341...176,137,318
Ensembl chr 2:176,136,341...176,137,318

G

boule homolog, RNA binding protein

multiple interactions

ISO

BOLL mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan]

NCBI chr 9:64,225,411...64,354,394
Ensembl chr 9:64,228,472...64,354,319

G

caspase 3

multiple interactions

ISO

[10-hydroxycamptothecin co-treated with Fluorouracil co-treated with Leucovorin] results in increased activity of CASP3 protein

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732

G

catalase

multiple interactions

EXP

[Fluorouracil co-treated with Leucovorin co-treated with 1,2-Dimethylhydrazine] results in increased expression of CAT protein

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526

G

cyclin D1

multiple interactions

EXP

[Methotrexate co-treated with Leucovorin] results in increased expression of CCND1 mRNA

NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810

G

cyclin E1

multiple interactions

ISO

[Leucovorin co-treated with Fluorouracil] results in increased expression of CCNE1 mRNA

NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:99,918,674...99,927,822

G

cell division cycle 45

multiple interactions

ISO

[Leucovorin co-treated with Fluorouracil] results in increased expression of CDC45 mRNA

NCBI chr11:95,689,702...95,714,980
Ensembl chr11:95,689,919...95,714,981

G

cell division cycle 6

multiple interactions

ISO

[Leucovorin co-treated with Fluorouracil] results in increased expression of CDC6 mRNA

NCBI chr10:84,360,361...84,374,239
Ensembl chr10:84,360,381...84,374,241

G

cyclin-dependent kinase 1

multiple interactions

ISO

[Leucovorin co-treated with Fluorouracil] results in increased expression of CDK1 mRNA

NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455

G

cyclin dependent kinase 2

multiple interactions

ISO

[Leucovorin co-treated with Fluorouracil] results in increased expression of CDK2 mRNA

NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878

G

cyclin-dependent kinase inhibitor 1A

multiple interactions

ISO

[Leucovorin co-treated with Fluorouracil] results in increased expression of CDKN1A mRNA

NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969

G

catenin beta 1

multiple interactions

EXP

[Methotrexate co-treated with Leucovorin] results in increased expression of CTNNB1 protein

NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662

G

cytochrome P450, family 11, subfamily a, polypeptide 1

multiple interactions

EXP

Leucovorin affects the reaction [Methotrexate results in decreased expression of CYP11A1 mRNA]; Leucovorin affects the reaction [Methotrexate results in decreased expression of CYP11A1 protein]

NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196

G

dihydrofolate reductase

multiple interactions
increases expression

ISO

Leucovorin inhibits the reaction [DHFR gene mutant form results in decreased abundance of Folic Acid]
Leucovorin results in increased expression of DHFR protein

PMID:16712799 PMID:21310277

NCBI chr 2:25,320,895...25,346,004

G

dihydropyrimidine dehydrogenase

multiple interactions

ISO

[Leucovorin co-treated with Fluorouracil] results in decreased activity of DPYD protein

NCBI chr 2:209,293,902...210,159,777
Ensembl chr 2:209,293,929...210,159,778

G

dopamine receptor D5

multiple interactions

ISO

DRD5 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan]

NCBI chr14:76,700,244...76,703,344
Ensembl chr14:76,700,241...76,703,466

G

endothelin 1

increases expression

ISO

Leucovorin results in increased expression of EDN1 mRNA; Leucovorin results in increased expression of EDN1 protein

NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687

G

EMAP like 2

multiple interactions

ISO

EML2 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan]

NCBI chr 1:87,955,924...87,987,366
Ensembl chr 1:87,955,606...87,987,366

G

ERCC excision repair 1, endonuclease non-catalytic subunit

multiple interactions

ISO

ERCC1 gene SNP affects the susceptibility to [Fluorouracil co-treated with Leucovorin co-treated with oxaliplatin]

NCBI chr 1:88,099,308...88,135,966
Ensembl chr 1:88,118,891...88,139,120

G

ERCC excision repair 2, TFIIH core complex helicase subunit

multiple interactions

ISO

ERCC2 gene SNP affects the susceptibility to [Fluorouracil co-treated with Leucovorin co-treated with oxaliplatin]

NCBI chr 1:88,161,342...88,175,102
Ensembl chr 1:88,160,988...88,175,102

G

coagulation factor VIII

multiple interactions

ISO

F8 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan]

NCBI chr18:155,237...187,186
Ensembl chr18:155,309...186,683

G

fatty acid binding protein 4

multiple interactions

EXP

Leucovorin inhibits the reaction [Methotrexate results in increased expression of FABP4 protein]

NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:93,488,271...93,492,972

G

folate receptor alpha

multiple interactions

ISO

FOLR1 protein affects the reaction [Leucovorin results in increased phosphorylation of STAT3 protein]

NCBI chr 1:165,631,462...165,650,430
Ensembl chr 1:165,631,462...165,642,669

G

follicle stimulating hormone subunit beta

multiple interactions

EXP

Leucovorin affects the reaction [Methotrexate results in increased expression of FSHB protein]

NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:114,003,262...114,007,072

G

glucose-6-phosphate dehydrogenase

multiple interactions

EXP

Leucovorin inhibits the reaction [Methotrexate results in decreased activity of G6PD protein]

NCBI chr X:157,352,364...157,372,144
Ensembl chr X:157,352,373...157,372,144

G

heart and neural crest derivatives expressed 2

increases expression

ISO

Leucovorin results in increased expression of HAND2 mRNA; Leucovorin results in increased expression of HAND2 protein

NCBI chr16:37,928,145...37,931,488
Ensembl chr16:37,928,145...37,931,488

G

heat shock protein family B (small) member 1

multiple interactions

ISO

HSPB1 protein affects the susceptibility to [Cisplatin co-treated with Fluorouracil co-treated with Leucovorin]

NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301

G

interleukin 1 beta

multiple interactions

ISO

Leucovorin inhibits the reaction [Methotrexate results in increased expression of IL1B mRNA]

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601

G

interleukin 6

multiple interactions

ISO

Leucovorin inhibits the reaction [Methotrexate results in increased expression of IL6 mRNA]

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610

G

interleukin 6 cytokine family signal transducer

multiple interactions

ISO

IL6ST protein affects the reaction [Leucovorin results in increased phosphorylation of STAT3 protein]

NCBI chr 2:45,798,872...45,839,501
Ensembl chr 2:45,799,380...45,843,182

G

lymphoid enhancer binding factor 1

multiple interactions

EXP

[Methotrexate co-treated with Leucovorin] results in increased expression of LEF1 mRNA

NCBI chr 2:222,340,541...222,453,931
Ensembl chr 2:222,340,704...222,453,929

G

galectin 8

multiple interactions

ISO

LGALS8 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan]

NCBI chr17:62,716,368...62,744,272
Ensembl chr17:62,719,828...62,744,482

G

luteinizing hormone subunit beta

multiple interactions

EXP

Leucovorin affects the reaction [Methotrexate results in increased expression of LHB protein]

NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445

G

methionine adenosyltransferase 2A

multiple interactions

ISO

Leucovorin inhibits the reaction [Methotrexate results in decreased expression of MAT2A mRNA]

NCBI chr 4:106,048,043...106,053,612
Ensembl chr 4:106,038,254...106,053,645

G

methylenetetrahydrofolate reductase

multiple interactions

ISO

MTHFR gene polymorphism results in increased susceptibility to [Fluorouracil co-treated with Leucovorin]

NCBI chr 5:163,748,346...163,768,141
Ensembl chr 5:163,748,321...163,768,105

G

peroxisome proliferator-activated receptor gamma

multiple interactions

EXP

[Methotrexate co-treated with Leucovorin] results in increased expression of PPARG mRNA; [Methotrexate co-treated with Leucovorin] results in increased expression of PPARG protein

NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104

G

serpin family E member 2

multiple interactions

ISO

SERPINE2 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan]

NCBI chr 9:88,573,138...88,637,252
Ensembl chr 9:88,573,149...88,637,202

G

secreted frizzled-related protein 1

multiple interactions

EXP

Leucovorin inhibits the reaction [Methotrexate results in increased expression of SFRP1 mRNA]; Leucovorin inhibits the reaction [Methotrexate results in increased expression of SFRP1 protein]

NCBI chr16:75,278,325...75,316,736
Ensembl chr16:75,278,325...75,316,736

G

solute carrier family 19 member 1

multiple interactions

ISO

Leucovorin inhibits the reaction [SLC19A1 protein results in increased transport of Methotrexate]

NCBI chr20:11,583,928...11,601,959
Ensembl chr20:11,583,929...11,601,488

G

solute carrier family 22 member 6

multiple interactions
increases uptake

EXP
ISO

Leucovorin inhibits the reaction [Methotrexate results in decreased expression of SLC22A6 protein]
SLC22A6 protein results in increased uptake of Leucovorin

PMID:16098483 PMID:16925582

NCBI chr 1:214,951,493...214,960,317
Ensembl chr 1:214,951,867...214,960,311

G

solute carrier family 22 member 8

multiple interactions
increases uptake

EXP
ISO

Leucovorin inhibits the reaction [Methotrexate results in decreased expression of SLC22A8 protein]
SLC22A8 protein results in increased uptake of Leucovorin

PMID:16098483 PMID:16925582

NCBI chr 1:214,925,506...214,945,516
Ensembl chr 1:214,925,508...214,946,588

G

solute carrier family 46 member 1

decreases activity
multiple interactions

ISO

Leucovorin results in decreased activity of SLC46A1 protein
Leucovorin inhibits the reaction [SLC46A1 protein results in increased transport of Folic Acid]

NCBI chr10:63,859,551...63,865,987
Ensembl chr10:63,859,504...63,866,869

G

suppressor of cytokine signaling 3

multiple interactions

ISO

Leucovorin inhibits the reaction [Pyrimethamine results in decreased expression of SOCS3 mRNA]

NCBI chr10:103,692,579...103,695,975
Ensembl chr10:103,690,976...103,704,825

G

Sp7 transcription factor

multiple interactions

EXP

[Methotrexate co-treated with Leucovorin] results in increased expression of SP7 mRNA

NCBI chr 7:135,363,193...135,373,376
Ensembl chr 7:135,363,199...135,373,559

G

steroidogenic acute regulatory protein

multiple interactions

EXP

Leucovorin affects the reaction [Methotrexate results in decreased expression of STAR mRNA]; Leucovorin affects the reaction [Methotrexate results in decreased expression of STAR protein]

NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447

G

signal transducer and activator of transcription 3

multiple interactions

ISO

FOLR1 protein affects the reaction [Leucovorin results in increased phosphorylation of STAT3 protein]; IL6ST protein affects the reaction [Leucovorin results in increased phosphorylation of STAT3 protein]; Leucovorin results in increased activity of and results in increased phosphorylation of STAT3 protein

NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359

G

thymidine phosphorylase

multiple interactions

ISO

TYMP mRNA affects the susceptibility to [irinotecan co-treated with Fluorouracil co-treated with Leucovorin]

NCBI chr 7:122,318,396...122,323,716
Ensembl chr 7:122,316,520...122,324,003

G

thymidylate synthetase

multiple interactions

ISO

[arsenic trioxide co-treated with Fluorouracil co-treated with Leucovorin] results in decreased expression of TYMS mRNA; TYMS gene polymorphism results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with Cisplatin co-treated with Paclitaxel]; TYMS mRNA affects the susceptibility to [irinotecan co-treated with Fluorouracil co-treated with Leucovorin]; TYMS promoter polymorphism results in increased susceptibility to [Fluorouracil co-treated with Leucovorin co-treated with oxaliplatin co-treated with docetaxel]; TYMS protein affects the susceptibility to [Fluorouracil co-treated with Leucovorin]
Leucovorin promotes the reaction [Fluorouracil results in decreased expression of TYMS]

PMID:9050858 PMID:16424979 PMID:17454858 PMID:18676755 PMID:19074750 More...

NCBI chr 9:120,760,057...120,776,149
Ensembl chr 9:120,763,386...120,776,097

G

Wnt family member 10B

multiple interactions

EXP

[Methotrexate co-treated with Leucovorin] results in increased expression of WNT10B mRNA

NCBI chr 7:131,801,046...131,806,850
Ensembl chr 7:131,801,046...131,806,850

G

X-ray repair cross complementing 1

multiple interactions

ISO

XRCC1 protein affects the susceptibility to [Fluorouracil co-treated with Leucovorin co-treated with Cisplatin]; XRCC1 protein affects the susceptibility to [Fluorouracil co-treated with Leucovorin co-treated with oxaliplatin]

NCBI chr 1:89,268,721...89,296,619
Ensembl chr 1:89,268,644...89,296,613

G

zinc finger protein 637

multiple interactions

ISO

ZNF32 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan]

NCBI chr 4:152,656,937...152,682,499
Ensembl chr 4:152,656,973...152,685,097

G

zinc finger protein 829 like, pseudogene 1

multiple interactions

ISO

ZNF582 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan]

NCBI chr 1:76,566,416...76,591,856

G

zinc finger (CCCH type), RNA binding motif and serine/arginine rich 2

multiple interactions

ISO

ZRSR2 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan]

NCBI chr X:34,179,279...34,201,989
Ensembl chr X:34,179,311...34,201,986

5-methyltetrahydrofolic acid

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aldehyde dehydrogenase 1 family, member L1

decreases abundance

ISO

ALDH1L1 protein results in decreased abundance of 5-methyltetrahydrofolate

NCBI chr 4:124,617,182...124,663,674
Ensembl chr 4:124,617,217...124,664,704

G

folate receptor alpha

increases uptake

ISO

FOLR1 protein results in increased uptake of 5-methyltetrahydrofolate

NCBI chr 1:165,631,462...165,650,430
Ensembl chr 1:165,631,462...165,642,669

G

glycine N-methyltransferase

affects binding

EXP

GNMT protein binds to 5-methyltetrahydrofolate

NCBI chr 9:21,752,235...21,756,368
Ensembl chr 9:21,752,266...21,755,692

G

methylenetetrahydrofolate reductase

increases chemical synthesis

ISO

MTHFR protein results in increased chemical synthesis of 5-methyltetrahydrofolate

PMID:7647779 PMID:9719624

NCBI chr 5:163,748,346...163,768,141
Ensembl chr 5:163,748,321...163,768,105

G

5-methyltetrahydrofolate-homocysteine methyltransferase

affects binding

ISO

5-methyltetrahydrofolate binds to MTR protein

NCBI chr17:62,911,705...62,996,544
Ensembl chr17:62,911,771...62,996,541

G

5-methyltetrahydrofolate-homocysteine methyltransferase reductase

affects abundance

ISO

MTRR protein affects the abundance of 5-methyltetrahydrofolate

NCBI chr 1:36,695,376...36,727,341
Ensembl chr 1:36,695,460...36,727,807

G

proliferating cell nuclear antigen

multiple interactions

ISO

[Docosahexaenoic Acids co-treated with 5-methyltetrahydrofolate] results in increased expression of PCNA protein

NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901

G

solute carrier family 19 member 1

multiple interactions
decreases activity

ISO
EXP

[5-methyltetrahydrofolate results in decreased activity of SLC19A1 protein] which results in decreased uptake of Folic Acid
5-methyltetrahydrofolate inhibits the reaction [SLC19A1 protein affects the transport of Methotrexate]

PMID:14612385 PMID:17034785

NCBI chr20:11,583,928...11,601,959
Ensembl chr20:11,583,929...11,601,488

G

solute carrier family 46 member 1

multiple interactions
decreases activity

ISO

5-methyltetrahydrofolate inhibits the reaction [SLC46A1 protein results in increased transport of Folic Acid]
5-methyltetrahydrofolate results in decreased activity of SLC46A1 protein

NCBI chr10:63,859,551...63,865,987
Ensembl chr10:63,859,504...63,866,869

G

serine/threonine kinase 11

multiple interactions

ISO

5-methyltetrahydrofolate inhibits the reaction [Palmitic Acid results in decreased phosphorylation of STK11 protein]; dorsomorphin inhibits the reaction [5-methyltetrahydrofolate inhibits the reaction [Palmitic Acid results in decreased phosphorylation of STK11 protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [5-methyltetrahydrofolate inhibits the reaction [Palmitic Acid results in decreased phosphorylation of STK11 protein]]

NCBI chr 7:10,225,204...10,241,965
Ensembl chr 7:10,225,204...10,241,965

7-Hydroxymethotrexate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily C member 4

affects response to substance

ISO

ABCC4 gene mutant form affects the susceptibility to 7-hydroxymethotrexate

NCBI chr15:101,948,387...102,182,912
Ensembl chr15:101,949,433...102,181,375

G

ATP binding cassette subfamily G member 2

affects transport
multiple interactions
increases export

ISO

ABCG2 protein affects the transport of 7-hydroxymethotrexate
Pantoprazole inhibits the reaction [ABCG2 protein affects the transport of 7-hydroxymethotrexate]; Protons promotes the reaction [ABCG2 protein results in increased export of 7-hydroxymethotrexate]

NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493

G

AT-rich interaction domain 5B

affects abundance

ISO

ARID5B gene SNP affects the abundance of 7-hydroxymethotrexate

NCBI chr20:20,305,693...20,489,689
Ensembl chr20:20,306,712...20,489,686

G

folylpolyglutamate synthase

decreases activity

ISO

7-hydroxymethotrexate results in decreased activity of FPGS protein

NCBI chr 3:36,370,505...36,391,314
Ensembl chr 3:36,370,300...36,391,068

G

gamma-glutamyl hydrolase

decreases response to substance

ISO

GGH mRNA results in decreased susceptibility to 7-hydroxymethotrexate

NCBI chr 5:38,326,747...38,349,655
Ensembl chr 5:38,326,594...38,349,647

G

methylenetetrahydrofolate reductase

decreases response to substance

ISO

MTHFR mRNA results in decreased susceptibility to 7-hydroxymethotrexate

NCBI chr 5:163,748,346...163,768,141
Ensembl chr 5:163,748,321...163,768,105

G

solute carrier organic anion transporter family, member 1a4

multiple interactions

ISO

7-hydroxymethotrexate inhibits the reaction [SLCO1A2 mRNA results in increased import of estrone sulfate]

NCBI chr 4:176,441,104...176,495,846
Ensembl chr 4:176,441,104...176,495,816

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

AKT serine/threonine kinase 1

multiple interactions

EXP

[Biotin co-treated with coenzyme Q10] inhibits the reaction [Aluminum Chloride results in decreased phosphorylation of AKT1 protein]; [Biotin co-treated with coenzyme Q10] inhibits the reaction [Aluminum Chloride results in increased cleavage of AKT1 protein]; Biotin inhibits the reaction [Aluminum Chloride results in decreased phosphorylation of AKT1 protein]; Biotin inhibits the reaction [Aluminum Chloride results in increased cleavage of AKT1 protein]

NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610

G

amyloid beta precursor protein

multiple interactions

EXP

[Biotin co-treated with coenzyme Q10] inhibits the reaction [Aluminum Chloride results in increased expression of APP protein]; Biotin inhibits the reaction [Aluminum Chloride results in increased expression of APP protein]

NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971

G

cyclin A2

increases expression

ISO

Biotin results in increased expression of CCNA2 mRNA

NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701

G

cyclin D3

increases expression

ISO

Biotin results in increased expression of CCND3 mRNA

NCBI chr 9:20,891,696...20,987,199
Ensembl chr 9:20,891,704...20,987,033

G

cyclin E1

increases expression

ISO

Biotin results in increased expression of CCNE1 mRNA

NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:99,918,674...99,927,822

G

cyclin dependent kinase 2

increases expression

ISO

Biotin results in increased expression of CDK2 mRNA

NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878

G

cyclin-dependent kinase 4

increases expression

ISO

Biotin results in increased expression of CDK4 mRNA

NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163

G

cyclin-dependent kinase inhibitor 1A

decreases expression

ISO

Biotin results in decreased expression of CDKN1A mRNA

NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969

G

cell death-inducing DFFA-like effector a

multiple interactions

ISO

[acetyl methyl tetramethyl tetralin co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in decreased expression of CIDEA mRNA

NCBI chr18:63,164,817...63,190,384
Ensembl chr18:63,164,099...63,190,382

G

cell death-inducing DFFA-like effector c

multiple interactions

ISO

[acetyl methyl tetramethyl tetralin co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in increased expression of CIDEC mRNA; [quinoxyfen co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in increased expression of CIDEC mRNA

NCBI chr 4:148,124,924...148,137,806
Ensembl chr 4:148,124,925...148,137,806

G

C-X-C motif chemokine ligand 11

decreases expression

ISO

Biotin results in decreased expression of CXCL11 mRNA

NCBI chr14:15,973,728...15,976,503
Ensembl chr14:15,973,720...15,976,567

G

cytochrome P450, family 1, subfamily b, polypeptide 1

multiple interactions
increases expression

ISO

Biotin results in increased expression of and results in increased activity of CYP1B1 protein
Biotin results in increased expression of CYP1B1 mRNA

PMID:15219929 PMID:15333708

NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142

G

cytochrome P450, family 2, subfamily e, polypeptide 1

multiple interactions

ISO

Biotin inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]

NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495

G

E2F transcription factor 1

increases expression

ISO

Biotin results in increased expression of E2F1 mRNA

NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:163,524,739...163,535,563

G

hemoglobin alpha, adult chain 2

multiple interactions

ISO

[Chromium co-treated with Biotin] results in decreased expression of HBA1 protein modified form; [chromium tripicolinate co-treated with Biotin] results in decreased expression of HBA1 protein modified form

NCBI chr10:15,828,291...15,829,138
Ensembl chr10:15,828,377...15,829,141

G

HECT and RLD domain containing E3 ubiquitin protein ligase 4

increases expression

ISO

Biotin results in increased expression of HERC4 mRNA

NCBI chr20:25,329,005...25,403,443
Ensembl chr20:25,328,822...25,403,372

G

histone cell cycle regulator

decreases expression

ISO

Biotin results in decreased expression of HIRA mRNA

NCBI chr11:95,528,831...95,637,565
Ensembl chr11:95,528,831...95,638,549

G

immunoglobulin heavy constant gamma 1

increases expression

ISO

Biotin results in increased expression of IGHG1 mRNA

G

interleukin 1 beta

multiple interactions

EXP

[Biotin co-treated with coenzyme Q10] inhibits the reaction [Aluminum Chloride results in increased expression of IL1B protein]; Biotin inhibits the reaction [Aluminum Chloride results in increased expression of IL1B protein]

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601

G

interleukin 6

multiple interactions

EXP

[Biotin co-treated with coenzyme Q10] inhibits the reaction [Aluminum Chloride results in increased expression of IL6 protein]; Biotin inhibits the reaction [Aluminum Chloride results in increased expression of IL6 protein]

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610

G

insulin 1

multiple interactions

ISO

[acetyl methyl tetramethyl tetralin co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in decreased expression of CIDEA mRNA; [acetyl methyl tetramethyl tetralin co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in decreased expression of SDHA protein; [acetyl methyl tetramethyl tetralin co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in increased expression of CIDEC mRNA; [quinoxyfen co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in decreased expression of SDHA protein; [quinoxyfen co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in increased expression of CIDEC mRNA

NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682

G

insulin receptor substrate 1

multiple interactions

EXP

[Biotin co-treated with coenzyme Q10] inhibits the reaction [Aluminum Chloride affects the phosphorylation of IRS1 protein]; Biotin inhibits the reaction [Aluminum Chloride affects the phosphorylation of IRS1 protein]

NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:90,993,519...91,054,538

G

lysosomal-associated membrane protein 1

decreases expression

ISO

Biotin results in decreased expression of LAMP1 mRNA

NCBI chr16:83,058,131...83,082,843
Ensembl chr16:83,058,385...83,075,159

G

mitogen activated protein kinase 1

increases expression

ISO

Biotin results in increased expression of MAPK1 protein

NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825

G

PPARG coactivator 1 alpha

increases expression

ISO

Biotin results in increased expression of PPARGC1A mRNA

NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213

G

succinate dehydrogenase complex flavoprotein subunit A

multiple interactions

ISO

[acetyl methyl tetramethyl tetralin co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in decreased expression of SDHA protein; [quinoxyfen co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in decreased expression of SDHA protein

NCBI chr 1:30,764,553...30,789,523
Ensembl chr 1:30,764,590...30,790,121

G

selectin E

affects binding

ISO

[Acetylglucosamine analog binds to Biotin] which binds to SELE protein

NCBI chr13:78,935,997...78,945,905
Ensembl chr13:78,936,036...78,945,903

G

selectin L

affects binding

EXP

[Acetylglucosamine analog binds to Biotin] which binds to SELL protein

NCBI chr13:78,950,100...78,969,604
Ensembl chr13:78,950,015...78,969,600

G

selectin P

affects binding

ISO

[Acetylglucosamine analog binds to Biotin] which binds to SELP protein

NCBI chr13:79,009,379...79,044,994
Ensembl chr13:79,009,475...79,044,987

G

solute carrier family 5 member 6

affects expression
increases transport
multiple interactions
increases uptake

ISO
EXP

Biotin affects the expression of SLC5A6 mRNA; Biotin affects the expression of SLC5A6 protein
SLC5A6 results in increased transport of Biotin
Sodium affects the reaction [SLC5A6 results in increased transport of Biotin]; Thioctic Acid inhibits the reaction [SLC5A6 results in increased transport of Biotin]
2,4-Dinitrophenol inhibits the reaction [SLC5A6 protein results in increased transport of Biotin]; 4-Chloromercuribenzenesulfonate inhibits the reaction [SLC5A6 protein results in increased transport of Biotin]; Azides inhibits the reaction [SLC5A6 protein results in increased transport of Biotin]; calmidazolium inhibits the reaction [SLC5A6 protein results in increased transport of Biotin]; chelerythrine inhibits the reaction [SLC5A6 protein results in increased transport of Biotin]; Gramicidin inhibits the reaction [SLC5A6 protein results in increased transport of Biotin]; Iodoacetates inhibits the reaction [SLC5A6 protein results in increased transport of Biotin]; Ouabain inhibits the reaction [SLC5A6 protein results in increased transport of Biotin]; Probenecid inhibits the reaction [SLC5A6 protein results in increased transport of Biotin]; Sodium affects the reaction [SLC5A6 results in increased transport of Biotin]; Sodium promotes the reaction [SLC5A6 protein results in increased transport of Biotin]; Staurosporine inhibits the reaction [SLC5A6 protein results in increased transport of Biotin]; Tetradecanoylphorbol Acetate promotes the reaction [SLC5A6 protein results in increased transport of Biotin]; Trifluoperazine inhibits the reaction [SLC5A6 protein results in increased transport of Biotin]
SLC5A6 results in increased uptake of Biotin
SLC5A6 protein results in increased transport of Biotin; SLC5A6 results in increased transport of Biotin

PMID:9516450 PMID:10329687 PMID:10516089 PMID:12646417 PMID:15561972

NCBI chr 6:31,039,865...31,051,671
Ensembl chr 6:31,040,017...31,051,670

G

Sp1 transcription factor

increases expression

ISO

Biotin results in increased expression of SP1 mRNA

NCBI chr 7:135,419,864...135,450,513
Ensembl chr 7:135,420,050...135,450,513

G

Sp3 transcription factor

increases expression

ISO

Biotin results in increased expression of SP3 mRNA

NCBI chr 3:78,219,421...78,272,318
Ensembl chr 3:78,219,426...78,264,517

G

transferrin

multiple interactions

ISO

[acetyl methyl tetramethyl tetralin co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in decreased expression of CIDEA mRNA; [acetyl methyl tetramethyl tetralin co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in decreased expression of SDHA protein; [acetyl methyl tetramethyl tetralin co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in increased expression of CIDEC mRNA; [quinoxyfen co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in decreased expression of SDHA protein; [quinoxyfen co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in increased expression of CIDEC mRNA

NCBI chr 8:112,668,667...112,695,376
Ensembl chr 8:112,647,642...112,695,400

G

transmembrane serine protease 15

increases expression

ISO

Biotin results in increased expression of TMPRSS15 mRNA

NCBI chr11:31,164,633...31,289,143
Ensembl chr11:31,164,633...31,288,953

G

tumor necrosis factor

multiple interactions

EXP

[Biotin co-treated with coenzyme Q10] inhibits the reaction [Aluminum Chloride results in increased expression of TNF protein]; Biotin inhibits the reaction [Aluminum Chloride results in increased expression of TNF protein]

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303

G

translocated promoter region, nuclear basket protein

increases expression

ISO

Biotin results in increased expression of TPR mRNA

NCBI chr13:64,974,419...65,037,604
Ensembl chr13:64,974,419...65,037,602

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

glutathione S-transferase pi 1

multiple interactions

ISO

cobamamide inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate]

NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705

cyanocob(III)alamin

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily B member 1A

decreases expression
multiple interactions

ISO

Vitamin B 12 results in decreased expression of ABCB1 mRNA; Vitamin B 12 results in decreased expression of ABCB1 protein
Vitamin B 12 inhibits the reaction [Methotrexate results in increased expression of ABCB1 mRNA]

NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135

G

ATP binding cassette subfamily C member 4

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of ABCC4 mRNA

NCBI chr15:101,948,387...102,182,912
Ensembl chr15:101,949,433...102,181,375

G

ATP binding cassette subfamily D member 4

affects metabolic processing

ISO

ABCD4 protein affects the metabolism of Vitamin B 12

NCBI chr 6:109,977,541...109,992,050
Ensembl chr 6:109,977,550...109,991,983

G

acetyl-CoA carboxylase alpha

multiple interactions

EXP

[Choline co-treated with Betaine co-treated with Vitamin B 12 co-treated with Folic Acid co-treated with Dietary Fats co-treated with Dietary Sucrose] results in increased expression of ACACA mRNA

NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,511,857...69,773,888

G

acetyl-CoA carboxylase beta

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of ACACB mRNA

NCBI chr12:48,026,394...48,138,214
Ensembl chr12:48,026,394...48,138,214

G

actin alpha 2, smooth muscle

multiple interactions

ISO

Vitamin B 12 inhibits the reaction [Dimethylnitrosamine results in increased expression of ACTA2 mRNA]

NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503

G

adhesion G protein-coupled receptor G2

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of ADGRG2 mRNA

NCBI chr X:38,106,067...38,231,286
Ensembl chr X:38,106,067...38,231,331

G

aldo-keto reductase family 1, member B7

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of AKR1B7 mRNA

NCBI chr 4:64,043,901...64,083,751
Ensembl chr 4:64,020,686...64,064,909

G

aldehyde dehydrogenase 2 family member

multiple interactions

ISO

[Betaine co-treated with Choline co-treated with Folic Acid co-treated with Methionine co-treated with Vitamin B 12 co-treated with Zinc Sulfate co-treated with Ethanol] results in increased expression of ALDH2 protein

NCBI chr12:40,610,244...40,643,220
Ensembl chr12:40,610,224...40,643,219

G

arsenite methyltransferase

multiple interactions

ISO

Folic Acid promotes the reaction [Vitamin B 12 promotes the reaction [AS3MT protein results in increased methylation of Arsenic]]; Vitamin B 12 promotes the reaction [AS3MT protein results in increased methylation of Arsenic]

NCBI chr 1:255,536,879...255,569,245
Ensembl chr 1:255,537,109...255,569,249

G

axin 1

multiple interactions

ISO

[Folic Acid co-treated with Vitamin B 12 co-treated with Betaine co-treated with Choline] results in increased methylation of AXIN1 gene

NCBI chr10:15,667,894...15,720,092
Ensembl chr10:15,667,958...15,720,092

G

brain-derived neurotrophic factor

multiple interactions

EXP

Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of BDNF protein]

NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657

G

caspase 3

multiple interactions

EXP

Folic Acid inhibits the reaction [Vitamin B 12 promotes the reaction [Dietary Fats results in increased expression of CASP3 mRNA]]; Vitamin B 12 inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Vitamin B 12 promotes the reaction [Dietary Fats results in increased expression of CASP3 mRNA]

PMID:23935743 PMID:38049026

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732

G

caspase 8

multiple interactions

EXP

Folic Acid inhibits the reaction [Vitamin B 12 promotes the reaction [Dietary Fats results in increased expression of CASP8 mRNA]]; Vitamin B 12 promotes the reaction [Dietary Fats results in increased expression of CASP8 mRNA]

NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699

G

catalase

multiple interactions

ISO
EXP

[Betaine co-treated with Choline co-treated with Folic Acid co-treated with Methionine co-treated with Vitamin B 12 co-treated with Zinc Sulfate co-treated with Ethanol] results in increased activity of CAT protein
Vitamin B 12 promotes the reaction [Folic Acid inhibits the reaction [arsenic trioxide results in decreased activity of CAT protein]]

PMID:16214333 PMID:20118189

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526

G

cystathionine beta synthase

multiple interactions

EXP

[Fatty Acids, Omega-3 co-treated with Folic Acid co-treated with Vitamin B 12 deficiency] results in increased expression of CBS mRNA; [Fatty Acids, Omega-3 co-treated with Vitamin B 12 deficiency] results in increased expression of CBS mRNA; [Folic Acid co-treated with Vitamin B 12 deficiency] results in increased expression of CBS mRNA

NCBI chr20:9,709,394...9,733,925
Ensembl chr20:9,709,395...9,734,066

G

C-C motif chemokine ligand 2

multiple interactions

EXP

[Choline co-treated with Betaine co-treated with Vitamin B 12 co-treated with Folic Acid co-treated with Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of CCL2 mRNA

NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875

G

CD40 molecule

multiple interactions

ISO

[Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in decreased expression of CD40 mRNA

NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:174,209,719...174,224,847

G

cyclin-dependent kinase 1

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of CDK1 mRNA

NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455

G

carboxylesterase 2C

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of CES2C mRNA

NCBI chr 1:270,377,201...270,384,768
Ensembl chr 1:270,374,913...270,384,801

G

cardiotrophin-like cytokine factor 1

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of CLCF1 mRNA

NCBI chr 1:210,937,763...210,947,064
Ensembl chr 1:210,937,255...210,947,064

G

C-reactive protein

multiple interactions

ISO

[Folic Acid co-treated with Riboflavin co-treated with Vitamin B 6 co-treated with Vitamin B 12] results in decreased expression of CRP protein; [Vitamin E co-treated with Ascorbic Acid co-treated with Folic Acid co-treated with Riboflavin co-treated with Vitamin B 6 co-treated with Vitamin B 12] results in decreased expression of CRP protein

NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514

G

cytochrome P450, family 26, subfamily a, polypeptide 1

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of CYP26A1 mRNA

NCBI chr 1:244,883,822...244,887,657
Ensembl chr 1:244,883,752...244,887,657

G

cytochrome P450, family 2, subfamily b, polypeptide 3

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of CYP2B10 mRNA

NCBI chr 1:90,780,468...90,859,852

G

cytochrome P450, family 2, subfamily c, polypeptide 24

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of CYP2C55 mRNA

NCBI chr 1:246,286,341...246,348,607
Ensembl chr 1:246,286,341...246,348,607

G

cytochrome P450, family 2, subfamily e, polypeptide 1

multiple interactions

ISO

[Betaine co-treated with Choline co-treated with Folic Acid co-treated with Methionine co-treated with Vitamin B 12 co-treated with Zinc Sulfate] inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein]

NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495

G

DNA-damage inducible transcript 3

multiple interactions

ISO
EXP

[Vitamin B 6 co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in increased expression of DDIT3 protein]
Vitamin B 12 inhibits the reaction [Streptozocin results in increased expression of DDIT3 protein]

PMID:37263574 PMID:38049026

NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509

G

DEPP autophagy regulator 1

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of DEPP1 mRNA

NCBI chr 4:151,583,105...151,585,455
Ensembl chr 4:151,581,502...151,586,233

G

E2F transcription factor 8

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of E2F8 mRNA

NCBI chr 1:107,701,985...107,720,538
Ensembl chr 1:107,701,985...107,720,009

G

epidermal growth factor receptor

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of EGFR mRNA

NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358

G

early growth response 1

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of EGR1 mRNA

NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843

G

eukaryotic translation initiation factor 2 alpha kinase 3

multiple interactions

EXP

Vitamin B 12 inhibits the reaction [Streptozocin results in increased phosphorylation of EIF2AK3 protein]

NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:104,363,833...104,425,268

G

establishment of sister chromatid cohesion N-acetyltransferase 2

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of ESCO2 mRNA

NCBI chr15:44,210,124...44,230,785
Ensembl chr15:44,210,641...44,231,304
Ensembl chr15:44,210,641...44,231,304

G

fatty acid binding protein 5

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of FABP5 mRNA

NCBI chr 2:93,672,451...93,676,186
Ensembl chr 2:93,672,458...93,676,127

G

fatty acid desaturase 1

multiple interactions

EXP

[Fatty Acids, Omega-3 co-treated with Vitamin B 12 deficiency] results in decreased expression of FADS1 mRNA; [Folic Acid co-treated with Vitamin B 12 deficiency] results in decreased expression of FADS1 mRNA; [Vitamin B 12 deficiency co-treated with Fatty Acids, Omega-3] results in decreased activity of FADS1 protein; Folic Acid inhibits the reaction [[Fatty Acids, Omega-3 co-treated with Vitamin B 12 deficiency] results in decreased expression of FADS1 mRNA]; Folic Acid promotes the reaction [[Vitamin B 12 deficiency co-treated with Fatty Acids, Omega-3] results in decreased activity of FADS1 protein]; Vitamin B 12 deficiency promotes the reaction [Folic Acid results in increased activity of FADS1 protein]

NCBI chr 1:216,252,605...216,267,618
Ensembl chr 1:216,252,602...216,267,615

G

fatty acid desaturase 2

multiple interactions

EXP

[Vitamin B 12 deficiency co-treated with Fatty Acids, Omega-3] results in decreased activity of FADS2 protein; [Vitamin B 12 deficiency co-treated with Folic Acid] results in decreased activity of FADS2 protein; Folic Acid inhibits the reaction [[Vitamin B 12 deficiency co-treated with Fatty Acids, Omega-3] results in decreased activity of FADS2 protein]

NCBI chr 1:216,132,277...216,172,190
Ensembl chr 1:216,133,676...216,172,066

G

fatty acid synthase

multiple interactions

EXP

[Choline co-treated with Betaine co-treated with Vitamin B 12 co-treated with Folic Acid] affects the reaction [[Dietary Fats co-treated with Dietary Sucrose] affects the methylation of FASN promoter]

NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583

G

folate hydrolase 1

multiple interactions

ISO

Vitamin B 12 affects the reaction [FOLH1 gene SNP affects the susceptibility to and affects the metabolism of Arsenic]

NCBI chr 1:149,828,286...149,914,313
Ensembl chr 1:149,840,760...149,914,035

G

fucosyltransferase 2

affects abundance

ISO

FUT2 gene polymorphism affects the abundance of Vitamin B 12

NCBI chr 1:105,256,013...105,276,828
Ensembl chr 1:105,255,390...105,276,647

G

growth arrest and DNA-damage-inducible, beta

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of GADD45B mRNA

NCBI chr 7:9,428,689...9,430,991
Ensembl chr 7:9,428,689...9,430,718

G

growth arrest and DNA-damage-inducible, gamma

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of GADD45G mRNA

NCBI chr17:13,528,606...13,530,351
Ensembl chr17:13,528,610...13,530,369

G

glucokinase

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in increased expression of GCK mRNA

NCBI chr14:84,999,019...85,041,098
Ensembl chr14:84,999,020...85,040,949

G

glial cell derived neurotrophic factor

multiple interactions

EXP

Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of GDNF protein]

NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:58,621,327...58,647,240

G

glial fibrillary acidic protein

multiple interactions

EXP

Vitamin B 12 inhibits the reaction [Streptozocin results in increased expression of GFAP protein]

NCBI chr10:88,352,987...88,361,661
Ensembl chr10:88,352,986...88,361,685

G

G protein subunit alpha 14

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of GNA14 mRNA

NCBI chr 1:223,141,802...223,324,210
Ensembl chr 1:223,141,802...223,324,210

G

glycerophosphocholine phosphodiesterase 1

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of GPCPD1 mRNA

NCBI chr 3:140,240,574...140,285,469
Ensembl chr 3:140,240,575...140,285,372

G

glutathione S-transferase alpha 5

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of GSTA5 mRNA; [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in increased expression of GSTA5 mRNA

NCBI chr 8:87,985,768...87,997,766
Ensembl chr 8:87,985,258...87,997,765

G

glutathione S-transferase, mu 5

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of GSTM3 mRNA

NCBI chr 2:198,219,769...198,222,732
Ensembl chr 2:198,219,647...198,222,731

G

guanylate cyclase 1 soluble subunit alpha 1

multiple interactions

ISO

3-(4-Amino-5-cyclopropylpyrimidine-2-yl)-1-(2-fluorobenzyl)-1H-pyrazolo(3,4-b)pyridine promotes the reaction [Vitamin B 12 results in increased activity of [GUCY1A1 protein binds to GUCY1B1 protein]]; Vitamin B 12 results in increased activity of [GUCY1A1 protein binds to GUCY1B1 protein]

NCBI chr 2:169,716,684...169,780,360
Ensembl chr 2:169,716,709...169,779,737

G

guanylate cyclase 1 soluble subunit beta 1

multiple interactions

ISO

3-(4-Amino-5-cyclopropylpyrimidine-2-yl)-1-(2-fluorobenzyl)-1H-pyrazolo(3,4-b)pyridine promotes the reaction [Vitamin B 12 results in increased activity of [GUCY1A1 protein binds to GUCY1B1 protein]]; Vitamin B 12 results in increased activity of [GUCY1A1 protein binds to GUCY1B1 protein]

NCBI chr 2:169,646,897...169,697,060
Ensembl chr 2:169,646,898...169,696,987

G

hepatitis A virus cellular receptor 1

multiple interactions

ISO

[Vitamin B 6 co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in increased expression of HAVCR1 protein]

NCBI chr10:31,619,914...31,652,955
Ensembl chr10:31,619,897...31,653,268

G

hemoglobin alpha, adult chain 2

affects expression
affects glycosylation

ISO

Vitamin B 12 affects the expression of HBA1 protein modified form
Vitamin B 12 affects the glycosylation of HBA1 protein

NCBI chr10:15,828,291...15,829,138
Ensembl chr10:15,828,377...15,829,141

G

heme oxygenase 1

multiple interactions

ISO

[Vitamin B 6 co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in decreased expression of HMOX1 protein]

NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818

G

heat shock protein family A (Hsp70) member 5

multiple interactions

EXP
ISO

Vitamin B 12 inhibits the reaction [Streptozocin results in increased expression of HSPA5 protein]
[Vitamin B 6 co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in increased expression of HSPA5 protein]

PMID:37263574 PMID:38049026

NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790

G

interleukin 1 beta

increases methylation
multiple interactions

ISO

Vitamin B 12 results in increased methylation of IL1B gene
[Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in decreased expression of IL1B mRNA; [Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in decreased secretion of IL1B protein; [Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased methylation of IL1B gene

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601

G

interleukin 6

multiple interactions

EXP

[Folic Acid co-treated with Vitamin B 12] inhibits the reaction [arsenic trioxide results in increased expression of IL6 protein]

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610

G

insulin receptor substrate 2

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of IRS2 mRNA

NCBI chr16:85,190,310...85,214,543
Ensembl chr16:85,190,111...85,214,543

G

integrin subunit alpha 8

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of ITGA8 mRNA

NCBI chr17:80,213,139...80,410,633
Ensembl chr17:80,213,143...80,410,633

G

integrin subunit beta 4

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of ITGB4 mRNA

NCBI chr10:101,705,592...101,741,933
Ensembl chr10:101,705,587...101,741,932

G

keratin 4

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of KRT4 mRNA

NCBI chr 7:134,924,753...134,931,050
Ensembl chr 7:134,924,753...134,930,713

G

kynureninase

multiple interactions

EXP

[Folic Acid co-treated with Vitamin B 12] inhibits the reaction [Rotenone results in decreased expression of KYNU mRNA]

NCBI chr 3:48,188,286...48,338,996
Ensembl chr 3:48,188,182...48,339,014

G

leptin receptor

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of LEPR mRNA

NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215

G

LRAT domain containing 1

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of LRATD1 mRNA

NCBI chr 6:42,646,515...42,650,988
Ensembl chr 6:42,640,190...42,651,204

G

leucine rich repeat containing 24

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of LRRC24 mRNA

NCBI chr 7:110,317,935...110,325,201
Ensembl chr 7:110,317,020...110,325,074

G

monoamine oxidase B

decreases activity

ISO

Vitamin B 12 results in decreased activity of MAOB protein

NCBI chr X:8,490,405...8,594,065
Ensembl chr X:8,490,344...8,594,375

G

microtubule-associated protein 2

multiple interactions

EXP

Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of MAP2 protein]

NCBI chr 9:75,173,038...75,431,606
Ensembl chr 9:75,288,262...75,428,459

G

mitogen activated protein kinase kinase kinase kinase 1

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of MAP4K1 mRNA

NCBI chr 1:93,398,460...93,419,996
Ensembl chr 1:93,398,454...93,419,993

G

mitogen activated protein kinase 1

multiple interactions

ISO

Vitamin B 12 inhibits the reaction [O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate results in increased phosphorylation of MAPK1 protein]

NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825

G

methionine adenosyltransferase 2A

multiple interactions

EXP

[Fatty Acids, Omega-3 co-treated with Vitamin B 12 deficiency] results in increased expression of MAT2A mRNA; [Folic Acid co-treated with Vitamin B 12 deficiency] results in increased expression of MAT2A mRNA; Fatty Acids, Omega-3 promotes the reaction [[Folic Acid co-treated with Vitamin B 12 deficiency] results in increased expression of MAT2A mRNA]

NCBI chr 4:106,048,043...106,053,612
Ensembl chr 4:106,038,254...106,053,645

G

myelin basic protein

multiple interactions

EXP

Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of MBP protein]

NCBI chr18:78,130,652...78,241,174
Ensembl chr18:78,130,325...78,241,174

G

minichromosome maintenance complex component 5

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of MCM5 mRNA

NCBI chr19:13,488,813...13,510,131
Ensembl chr19:13,488,813...13,517,758

G

minichromosome maintenance complex component 6

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of MCM6 mRNA

NCBI chr13:42,379,161...42,404,352
Ensembl chr13:42,379,162...42,465,467

G

microtubule associated monooxygenase, calponin and LIM domain containing 1

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of MICAL1 mRNA

NCBI chr20:46,547,983...46,568,487
Ensembl chr20:46,556,536...46,568,487

G

microRNA 142

multiple interactions

ISO

[Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [sodium arsenite results in decreased expression of MIR142]

NCBI chr10:73,055,104...73,055,190
Ensembl chr10:73,055,097...73,055,207

G

marker of proliferation Ki-67

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of MKI67 mRNA

NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593

G

metabolism of cobalamin associated C

increases metabolic processing
affects binding
decreases metabolic processing

ISO

MMACHC protein results in increased metabolism of Vitamin B 12
Vitamin B 12 analog binds to MMACHC protein; Vitamin B 12 binds to MMACHC protein
MMACHC protein mutant form results in decreased metabolism of Vitamin B 12

NCBI chr 5:135,403,094...135,409,285
Ensembl chr 5:135,402,404...135,409,235

G

methylenetetrahydrofolate reductase

decreases expression
multiple interactions

EXP

Vitamin B 12 deficiency results in decreased expression of MTHFR mRNA
[Folic Acid co-treated with Vitamin B 12 deficiency] results in decreased expression of MTHFR mRNA; Fatty Acids, Omega-3 inhibits the reaction [Vitamin B 12 deficiency results in decreased expression of MTHFR mRNA]

NCBI chr 5:163,748,346...163,768,141
Ensembl chr 5:163,748,321...163,768,105

G

5-methyltetrahydrofolate-homocysteine methyltransferase

affects binding
multiple interactions
increases activity

ISO
EXP

Vitamin B 12 binds to MTR protein
[Fatty Acids, Omega-3 co-treated with Vitamin B 12 deficiency] results in decreased expression of MTR mRNA; Fatty Acids, Omega-3 promotes the reaction [Vitamin B 12 deficiency inhibits the reaction [Fatty Acids, Omega-3 results in increased expression of MTR mRNA]]; Vitamin B 12 deficiency inhibits the reaction [Fatty Acids, Omega-3 results in increased expression of MTR mRNA]
Vitamin B 12 results in increased activity of MTR protein

PMID:17477549 PMID:17982279 PMID:25003120

NCBI chr17:62,911,705...62,996,544
Ensembl chr17:62,911,771...62,996,541

G

MYCL proto-oncogene, bHLH transcription factor

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of MYCL mRNA

NCBI chr 5:140,559,843...140,566,704
Ensembl chr 5:140,560,152...140,566,699

G

neutrophil cytosolic factor 1

multiple interactions

ISO

[Vitamin B 6 co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in increased expression of NCF1 protein]

NCBI chr12:28,121,816...28,131,080
Ensembl chr12:28,121,366...28,131,079

G

NFE2 like bZIP transcription factor 2

multiple interactions

ISO

[Vitamin B 6 co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in decreased expression of NFE2L2 protein]

NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090

G

nerve growth factor

multiple interactions

EXP

Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of NGF protein]

NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:192,589,582...192,643,834

G

NLR family, pyrin domain containing 12

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of NLRP12 mRNA

NCBI chr 1:74,848,020...74,885,945
Ensembl chr 1:74,848,063...74,876,341

G

neuropeptide Y

multiple interactions

ISO

Vitamin B 12 affects the reaction [bisphenol A affects the expression of NPY mRNA]

NCBI chr 4:80,212,111...80,219,310
Ensembl chr 4:80,212,111...80,219,310

G

NAD(P)H quinone dehydrogenase 1

multiple interactions

ISO

[Vitamin B 6 co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in decreased expression of NQO1 protein]

NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260

G

phosphatidylethanolamine N-methyltransferase

multiple interactions

EXP

[Fatty Acids, Omega-3 co-treated with Vitamin B 12 deficiency] results in increased expression of PEMT mRNA; [Folic Acid co-treated with Vitamin B 12 deficiency] results in increased expression of PEMT mRNA; Fatty Acids, Omega-3 inhibits the reaction [[Folic Acid co-treated with Vitamin B 12 deficiency] results in increased expression of PEMT mRNA]

NCBI chr10:45,275,434...45,349,651
Ensembl chr10:45,275,412...45,420,037

G

period circadian regulator 2

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in increased expression of PER2 mRNA

NCBI chr 9:99,454,828...99,497,069
Ensembl chr 9:99,454,830...99,496,993

G

peroxisome proliferator activated receptor alpha

multiple interactions

ISO

[Betaine co-treated with Choline co-treated with Folic Acid co-treated with Methionine co-treated with Vitamin B 12 co-treated with Zinc Sulfate co-treated with Ethanol] results in increased expression of PPARA protein

NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714

G

peroxisome proliferator-activated receptor gamma

multiple interactions

EXP

[Folic Acid co-treated with Vitamin B 12] inhibits the reaction [Dietary Fats results in decreased expression of PPARG mRNA]; Vitamin B 12 inhibits the reaction [Dietary Fats results in decreased expression of PPARG mRNA]

NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104

G

protein phosphatase 1, regulatory subunit 3G

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of PPP1R3G mRNA

NCBI chr17:29,080,407...29,083,739
Ensembl chr17:29,070,658...29,085,135

G

serine protease 8

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of PRSS8 mRNA

NCBI chr 1:191,966,701...191,971,271
Ensembl chr 1:191,966,701...191,971,193

G

regulatory factor X4

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of RFX4 mRNA

NCBI chr 7:20,740,760...20,903,355
Ensembl chr 7:20,741,079...20,902,851

G

regulator of G-protein signaling 16

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of RGS16 mRNA

NCBI chr13:68,421,480...68,443,312
Ensembl chr13:68,438,120...68,443,313

G

ribonucleotide reductase regulatory subunit M2

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of RRM2 mRNA

NCBI chr 6:47,044,755...47,075,370
Ensembl chr 6:47,067,690...47,075,370

G

S100 calcium binding protein A8

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of S100A8 mRNA

NCBI chr 2:178,464,095...178,465,223
Ensembl chr 2:178,464,702...178,465,221

G

serpin family E member 1

multiple interactions
increases methylation

ISO

[Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SERPINE1 mRNA; [Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased methylation of SERPINE1 gene
Vitamin B 12 results in increased methylation of SERPINE1 gene

NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357

G

serpin family H member 1

multiple interactions

ISO

Vitamin B 12 inhibits the reaction [Dimethylnitrosamine results in increased expression of SERPINH1 mRNA]

NCBI chr 1:163,055,630...163,063,177
Ensembl chr 1:163,055,630...163,062,976

G

solute carrier family 25, member 30

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of SLC25A30 mRNA

NCBI chr15:57,486,346...57,508,981
Ensembl chr15:57,486,350...57,502,690

G

suppressor of cytokine signaling 2

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of SOCS2 mRNA

NCBI chr 7:31,890,564...31,932,092
Ensembl chr 7:31,874,463...31,930,423

G

sulfotransferase family 1E member 1

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of SULT1E1 mRNA

NCBI chr14:20,700,444...20,718,719
Ensembl chr14:20,700,292...20,718,716

G

synaptophysin

multiple interactions

EXP

Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of SYP protein]

NCBI chr X:17,521,348...17,536,449
Ensembl chr X:17,521,348...17,536,984

G

transcobalamin 2

multiple interactions

ISO

TCN2 protein binds to and results in increased uptake of Vitamin B 12

NCBI chr14:83,036,935...83,052,187
Ensembl chr14:83,036,935...83,051,552

G

tyrosine hydroxylase

multiple interactions

EXP

Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of TH protein]

NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:207,500,962...207,557,227

G

tumor necrosis factor

multiple interactions

EXP
ISO

[Folic Acid co-treated with Vitamin B 12] inhibits the reaction [arsenic trioxide results in increased expression of TNF protein]
[Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in decreased expression of TNF mRNA; [Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in decreased secretion of TNF protein

PMID:16214333 PMID:30116142

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303

G

unc-51 like autophagy activating kinase 1

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of ULK1 mRNA

NCBI chr12:51,511,492...51,537,746
Ensembl chr12:51,511,492...51,537,746

G

ubiquitin specific peptidase 2

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in increased expression of USP2 mRNA

NCBI chr 8:53,308,264...53,336,800
Ensembl chr 8:53,308,303...53,336,794

G

vanin 1

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of VNN1 mRNA

NCBI chr 1:23,356,324...23,366,629
Ensembl chr 1:23,356,330...23,366,629

dihydrofolic acid

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

hydroxymethylbilane synthase

increases activity

EXP

Dihydrofolic acid increases activity of purified Hmbs protein

RGD

NCBI chr 8:53,570,364...53,577,758
Ensembl chr 8:53,570,364...53,577,802

G

insulin-like growth factor 1 receptor

decreases expression

ISO

dihydrofolate results in decreased expression of IGF1R mRNA

NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:130,959,997...131,248,664

G

N-acetyltransferase 1

decreases activity

ISO

dihydrofolate results in decreased activity of NAT1 protein

NCBI chr16:26,984,882...27,005,194
Ensembl chr16:26,982,625...26,986,527

G

PPARG coactivator 1 alpha

increases expression

ISO

dihydrofolate results in increased expression of PPARGC1A mRNA

NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213

G

solute carrier family 19 member 1

multiple interactions
decreases activity

EXP

dihydrofolate inhibits the reaction [SLC19A1 protein affects the transport of Methotrexate]
dihydrofolate results in decreased activity of SLC19A1 protein

NCBI chr20:11,583,928...11,601,959
Ensembl chr20:11,583,929...11,601,488

FAD

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

NADH:ubiquinone oxidoreductase subunit A9

multiple interactions

ISO

Flavin-Adenine Dinucleotide binds to and results in increased activity of NDUFA9 protein

NCBI chr 4:161,345,398...161,374,188
Ensembl chr 4:161,345,400...161,375,025

G

riboflavin kinase

increases abundance

ISO

RFK protein results in increased abundance of Flavin-Adenine Dinucleotide

NCBI chr 1:224,226,632...224,234,185
Ensembl chr 1:224,226,628...224,235,698
Ensembl chr X:224,226,628...224,235,698

G

solute carrier family 52 member 3

multiple interactions

EXP

Flavin-Adenine Dinucleotide inhibits the reaction [SLC52A3 protein results in increased transport of Riboflavin]

NCBI chr 3:160,959,233...160,976,170
Ensembl chr 3:160,965,302...160,974,692

FMN

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

isocitrate dehydrogenase (NADP(+)) 2

multiple interactions
increases abundance

ISO

Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Flavin Mononucleotide]

NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:143,439,323...143,467,248

G

riboflavin kinase

increases abundance

ISO

RFK protein results in increased abundance of Flavin Mononucleotide

NCBI chr 1:224,226,632...224,234,185
Ensembl chr 1:224,226,628...224,235,698
Ensembl chr X:224,226,628...224,235,698

G

solute carrier family 52 member 3

multiple interactions

EXP

Flavin Mononucleotide inhibits the reaction [SLC52A3 protein results in increased transport of Riboflavin]

NCBI chr 3:160,959,233...160,976,170
Ensembl chr 3:160,965,302...160,974,692

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alpha 1,4-galactosyltransferase

decreases expression

ISO

Folic Acid results in decreased expression of A4GALT mRNA

NCBI chr 7:116,248,571...116,272,917
Ensembl chr 7:116,247,880...116,273,171

G

aladin WD repeat nucleoporin

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of AAAS mRNA]

NCBI chr 7:135,342,901...135,362,545
Ensembl chr 7:135,342,901...135,362,545

G

acetoacetyl-CoA synthetase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AACS mRNA

NCBI chr12:36,774,471...36,817,835
Ensembl chr12:36,774,471...36,822,543

G

arylacetamide deacetylase

multiple interactions

ISO

[Folic Acid deficiency co-treated with Methotrexate] results in increased expression of AADAC mRNA

NCBI chr 2:146,293,449...146,351,061
Ensembl chr 2:146,313,279...146,324,525

G

alpha- and gamma-adaptin binding protein

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AAGAB mRNA

NCBI chr 8:72,978,719...73,017,275
Ensembl chr 8:72,978,741...73,017,278

G

AP2 associated kinase 1

decreases expression

ISO

Folic Acid results in decreased expression of AAK1 mRNA

NCBI chr 4:120,845,012...121,009,170
Ensembl chr 4:120,858,557...121,004,236

G

adipogenesis associated, Mth938 domain containing

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AAMDC mRNA

NCBI chr 1:161,273,205...161,303,253
Ensembl chr 1:161,262,347...161,299,340

G

angio-associated, migratory cell protein

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of AAMP mRNA]

NCBI chr 9:83,312,519...83,318,325
Ensembl chr 9:83,312,519...83,318,325

G

aralkylamine N-acetyltransferase

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of AANAT mRNA]

NCBI chr10:102,323,647...102,330,639
Ensembl chr10:102,326,135...102,330,635

G

alanine and arginine rich domain containing protein

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of AARD gene
Folic Acid results in decreased expression of AARD mRNA

PMID:20938992 PMID:25629700

NCBI chr 7:85,254,322...85,259,163
Ensembl chr 7:85,253,992...85,259,163

G

alanyl-tRNA synthetase 1

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of AARS1 mRNA]

NCBI chr19:55,906,694...55,930,499
Ensembl chr19:55,906,702...55,930,497

G

alanyl-tRNA synthetase domain containing 1

increases expression

ISO

Folic Acid results in increased expression of AARSD1 mRNA

NCBI chr10:86,840,874...86,854,077
Ensembl chr10:86,840,874...86,849,734

G

aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase

decreases expression

ISO

Folic Acid results in decreased expression of AASDHPPT mRNA

NCBI chr 8:9,731,592...9,748,934
Ensembl chr 8:9,738,172...9,748,953

G

4-aminobutyrate aminotransferase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ABAT mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ABAT mRNA

PMID:20938992 PMID:22206623

NCBI chr10:7,503,351...7,599,474
Ensembl chr10:7,492,022...7,599,474

G

ATP binding cassette subfamily A member 1

multiple interactions
decreases expression
increases expression

ISO

[Folic Acid deficiency co-treated with Methotrexate] results in increased expression of ABCA1 mRNA
Folic Acid results in decreased expression of ABCA1 mRNA
Folic Acid results in increased expression of ABCA1 mRNA

PMID:21867686 PMID:24657277 PMID:25629700

NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:72,473,676...72,596,473

G

ATP binding cassette subfamily A member 13

decreases expression

ISO

Folic Acid results in decreased expression of ABCA13 mRNA

NCBI chr14:88,087,146...88,589,868
Ensembl chr14:88,087,801...88,589,392

G

ATP binding cassette subfamily A member 5

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ABCA5 mRNA
Folic Acid results in decreased expression of ABCA5 mRNA

PMID:20938992 PMID:25629700

NCBI chr10:95,739,610...95,808,633
Ensembl chr10:95,739,610...95,808,424

G

ATP binding cassette subfamily A member 7

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ABCA7 mRNA

NCBI chr 7:10,342,092...10,362,094
Ensembl chr 7:10,342,092...10,361,989

G

ATP binding cassette subfamily B member 10

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ABCB10 mRNA

NCBI chr19:68,850,108...68,881,689
Ensembl chr19:68,850,134...68,880,203

G

ATP binding cassette subfamily B member 11

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ABCB11 mRNA

NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581

G

ATP binding cassette subfamily B member 1A

decreases expression

ISO

Folic Acid results in decreased expression of ABCB1A mRNA

NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135

G

ATP-binding cassette, sub-family B member 1B

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ABCB1B mRNA

NCBI chr 4:26,197,706...26,280,156
Ensembl chr 4:26,106,903...26,279,567

G

ATP binding cassette subfamily B member 5

decreases expression

ISO

Folic Acid results in decreased expression of ABCB5 mRNA

NCBI chr 6:145,978,860...146,075,776
Ensembl chr 6:145,978,906...146,077,039

G

ATP binding cassette subfamily B member 6

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ABCB6 mRNA

NCBI chr 9:84,117,222...84,125,939
Ensembl chr 9:84,117,220...84,125,526

G

ATP binding cassette subfamily B member 8

increases expression
multiple interactions

ISO

Folic Acid results in increased expression of ABCB8 mRNA
Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ABCB8 mRNA]

PMID:22206623 PMID:25629700

NCBI chr 4:11,660,716...11,676,030
Ensembl chr 4:11,660,716...11,676,002

G

ATP binding cassette subfamily B member 9

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ABCB9 mRNA

NCBI chr12:38,146,659...38,192,862
Ensembl chr12:38,159,904...38,192,860

G

ATP binding cassette subfamily C member 1

affects activity
decreases expression
multiple interactions
affects expression

ISO

Folic Acid affects the activity of ABCC1 protein
Folic Acid results in decreased expression of ABCC1 mRNA
[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ABCC1 mRNA
Folic Acid deficiency inhibits the reaction [ABCC1 protein results in increased secretion of Daunorubicin]
Folic Acid affects the expression of ABCC1 protein

PMID:15041471 PMID:15657365 PMID:20938992 PMID:25629700

NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404

G

ATP binding cassette subfamily C member 12

increases expression

ISO

Folic Acid results in increased expression of ABCC12 mRNA

NCBI chr19:36,722,550...36,798,868
Ensembl chr19:36,722,575...36,793,993

G

ATP binding cassette subfamily C member 3

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ABCC3 mRNA; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of ABCC3 mRNA]

PMID:20938992 PMID:22206623

NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,793,583...79,839,494

G

ATP binding cassette subfamily C member 4

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of ABCC4 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ABCC4 mRNA

PMID:20938992 PMID:33549593

NCBI chr15:101,948,387...102,182,912
Ensembl chr15:101,949,433...102,181,375

G

ATP binding cassette subfamily C member 5

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ABCC5 gene; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of ABCC5; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ABCC5 mRNA
Folic Acid results in decreased expression of ABCC5 mRNA

PMID:20938992 PMID:25629700

NCBI chr11:93,975,579...94,071,659
Ensembl chr11:93,978,274...94,071,655

G

ATP binding cassette subfamily C member 8

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ABCC8 mRNA

NCBI chr 1:105,734,992...105,816,272
Ensembl chr 1:105,734,992...105,815,982

G

ATP binding cassette subfamily C member 9

decreases expression

ISO

Folic Acid results in decreased expression of ABCC9 mRNA

NCBI chr 4:177,262,848...177,386,837
Ensembl chr 4:177,262,848...177,386,348

G

ATP binding cassette subfamily D member 3

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of ABCD3 mRNA]

NCBI chr 2:212,536,791...212,590,379
Ensembl chr 2:212,536,791...212,590,504

G

ATP binding cassette subfamily D member 4

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ABCD4 mRNA]

NCBI chr 6:109,977,541...109,992,050
Ensembl chr 6:109,977,550...109,991,983

G

ATP binding cassette subfamily E member 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ABCE1 mRNA

NCBI chr19:45,109,880...45,134,819
Ensembl chr19:45,109,906...45,134,819

G

ATP binding cassette subfamily F member 1

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ABCF1 mRNA]

NCBI chr20:2,807,315...2,820,240
Ensembl chr20:2,807,106...2,820,240

G

ATP binding cassette subfamily F member 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ABCF2 gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ABCF2 mRNA]

PMID:20938992 PMID:22206623

NCBI chr 4:11,485,865...11,500,067
Ensembl chr 4:11,487,395...11,500,053

G

ATP binding cassette subfamily G member 2

affects transport
increases expression
multiple interactions
decreases expression

ISO
EXP

ABCG2 protein affects the transport of Folic Acid
Folic Acid deficiency results in increased expression of ABCG2 mRNA; Folic Acid deficiency results in increased expression of ABCG2 protein
[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ABCG2 gene
Folic Acid results in decreased expression of ABCG2 mRNA; Folic Acid results in decreased expression of ABCG2 protein
[3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCG2 protein] inhibits the reaction [Folic Acid deficiency results in decreased susceptibility to Mitoxantrone]; [Folic Acid deficiency results in increased expression of ABCG2 protein] which results in decreased susceptibility to Mitoxantrone; Folic Acid affects the localization of and affects the expression of ABCG2 protein; Protons promotes the reaction [ABCG2 protein results in increased transport of Folic Acid]

PMID:15657365 PMID:17032904 PMID:18623116 PMID:19552531 PMID:20938992

NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493

G

ATP binding cassette subfamily G member 4

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of ABCG4 mRNA
Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of ABCG4 mRNA]

PMID:22206623 PMID:25629700

NCBI chr 8:53,508,005...53,525,314
Ensembl chr 8:53,508,005...53,523,571

G

abhydrolase domain containing 10, depalmitoylase

decreases expression

ISO

Folic Acid results in decreased expression of ABHD10 mRNA

NCBI chr11:68,543,860...68,556,059
Ensembl chr11:68,543,606...68,557,640

G

abhydrolase domain containing 11

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ABHD11 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ABHD11 gene

PMID:20938992 PMID:22206623

NCBI chr12:27,318,739...27,322,016
Ensembl chr12:27,318,749...27,321,970

G

abhydrolase domain containing 12, lysophospholipase

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ABHD12 gene

NCBI chr 3:160,119,724...160,179,959
Ensembl chr 3:160,119,724...160,179,969

G

abhydrolase domain containing 12B

decreases expression

ISO

Folic Acid results in decreased expression of ABHD12B mRNA

NCBI chr 6:94,404,594...94,432,395
Ensembl chr 6:94,404,594...94,432,395

G

abhydrolase domain containing 13

decreases expression

ISO

Folic Acid results in decreased expression of ABHD13 mRNA

PMID:21867686 PMID:25629700

NCBI chr16:86,203,851...86,218,843
Ensembl chr16:86,201,794...86,290,906

G

abhydrolase domain containing 15

increases expression

ISO

Folic Acid results in increased expression of ABHD15 mRNA

NCBI chr10:62,861,335...62,866,726
Ensembl chr10:62,861,317...62,868,540

G

abhydrolase domain containing 17A, depalmitoylase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ABHD17A mRNA

NCBI chr 7:9,775,016...9,781,447

G

abhydrolase domain containing 17B, depalmitoylase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ABHD17B mRNA

NCBI chr 1:228,624,821...228,659,254
Ensembl chr 1:228,624,499...228,658,948

G

abhydrolase domain containing 2, acylglycerol lipase

multiple interactions

ISO

[Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of ABHD2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ABHD2 mRNA

PMID:20938992 PMID:29127188

NCBI chr 1:142,626,748...142,707,892
Ensembl chr 1:142,626,732...142,712,674

G

abhydrolase domain containing 5, lysophosphatidic acid acyltransferase

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of ABHD5 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ABHD5 mRNA

PMID:22206623 PMID:25629700

NCBI chr 8:130,877,834...130,903,947
Ensembl chr 8:130,877,703...130,903,947

G

abhydrolase domain containing 6, acylglycerol lipase

decreases expression

ISO

Folic Acid results in decreased expression of ABHD6 mRNA

NCBI chr15:19,289,967...19,337,500
Ensembl chr15:19,289,969...19,337,193

G

abl-interactor 1

decreases expression

ISO

Folic Acid results in decreased expression of ABI1 mRNA

NCBI chr17:90,006,917...90,088,002
Ensembl chr17:90,006,925...90,087,827

G

abl-interactor 2

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of ABI2 mRNA]

NCBI chr 9:69,321,072...69,490,630
Ensembl chr 9:69,321,150...69,490,597

G

actin binding LIM protein family, member 2

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of ABLIM2 mRNA]

NCBI chr14:79,090,046...79,214,986
Ensembl chr14:79,090,923...79,214,972

G

actin binding LIM protein family, member 3

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ABLIM3 mRNA

NCBI chr18:57,527,917...57,646,936
Ensembl chr18:57,527,917...57,646,710

G

ABR activator of RhoGEF and GTPase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ABR mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ABR mRNA

PMID:20938992 PMID:22206623

NCBI chr10:61,760,743...61,959,526
Ensembl chr10:61,760,743...61,959,467

G

actin-binding Rho activating protein

decreases expression

ISO

Folic Acid results in decreased expression of ABRA mRNA

PMID:21867686 PMID:25629700

NCBI chr 7:74,855,008...74,859,076
Ensembl chr 7:74,855,007...74,859,076

G

ABRA C-terminal like

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ABRACL mRNA

NCBI chr 1:14,474,802...14,484,992
Ensembl chr 1:14,474,803...14,485,055

G

abraxas 1, BRCA1 A complex subunit

decreases expression

ISO

Folic Acid results in decreased expression of FAM175A mRNA

NCBI chr14:9,100,650...9,115,012
Ensembl chr14:9,100,671...9,115,011

G

abraxas 2, BRISC complex subunit

decreases expression

ISO

Folic Acid results in decreased expression of ABRAXAS2 mRNA

PMID:21867686 PMID:25629700

NCBI chr 1:197,077,177...197,102,753
Ensembl chr 1:197,077,158...197,102,757

G

ankyrin repeat and BTB domain containing 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ABTB1 gene

NCBI chr 4:122,856,558...122,862,895
Ensembl chr 4:122,856,564...122,862,789

G

acetyl-CoA acyltransferase 1A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ACAA1A mRNA

NCBI chr 8:127,956,126...127,966,348
Ensembl chr 8:127,956,129...127,966,241

G

acetyl-Coenzyme A acyltransferase 1B

increases expression

ISO

Folic Acid results in increased expression of ACAA1B mRNA

NCBI chr 8:127,750,771...127,759,589
Ensembl chr 8:127,750,743...127,759,569

G

acetyl-CoA acyltransferase 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ACAA2 mRNA

NCBI chr18:70,620,310...70,648,417
Ensembl chr18:70,620,110...70,648,420

G

acetyl-CoA carboxylase alpha

multiple interactions
increases expression

EXP
ISO

[Choline co-treated with Betaine co-treated with Vitamin B 12 co-treated with Folic Acid co-treated with Dietary Fats co-treated with Dietary Sucrose] results in increased expression of ACACA mRNA; [Dietary Fats co-treated with Dietary Sucrose co-treated with Folic Acid] results in decreased expression of ACACA protein; [Folic Acid deficiency co-treated with Methionine deficiency co-treated with Choline deficiency] results in decreased expression of ACACA mRNA
Folic Acid deficiency results in increased expression of ACACA mRNA

PMID:19566968 PMID:22648174 PMID:29056104 PMID:30153273

NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,511,857...69,773,888

G

acetyl-CoA carboxylase beta

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ACACB mRNA; [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of ACACB mRNA
Folic Acid results in decreased expression of ACACB mRNA

PMID:21867686 PMID:22206623 PMID:33549593

NCBI chr12:48,026,394...48,138,214
Ensembl chr12:48,026,394...48,138,214

G

acyl-CoA dehydrogenase family, member 10

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ACAD10 mRNA

NCBI chr12:40,561,900...40,604,378
Ensembl chr12:40,566,701...40,604,378

G

acyl-CoA dehydrogenase family, member 9

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ACAD9 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ACAD9 gene

PMID:20938992 PMID:22206623

NCBI chr 2:120,871,329...120,894,306
Ensembl chr 2:120,871,227...120,894,709

G

acyl-CoA dehydrogenase, long chain

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of ACADL mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ACADL mRNA

PMID:22206623 PMID:25629700

NCBI chr 9:75,783,689...75,822,077
Ensembl chr 9:75,783,689...75,822,164

G

acyl-CoA dehydrogenase medium chain

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ACADM mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ACADM mRNA
Folic Acid results in decreased expression of ACADM mRNA

PMID:22206623 PMID:22872676 PMID:25629700

NCBI chr 2:245,518,693...245,542,864
Ensembl chr 2:245,518,693...245,542,864

G

acyl-CoA dehydrogenase short chain

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ACADS mRNA]

NCBI chr12:47,154,259...47,163,580
Ensembl chr12:47,154,276...47,164,103

G

ArfGAP with coiled-coil, ankyrin repeat and PH domains 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ACAP3 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ACAP3 gene

PMID:20938992 PMID:22206623

NCBI chr 5:171,783,382...171,797,709
Ensembl chr 5:171,783,382...171,798,191

G

acetyl-CoA acetyltransferase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ACAT1 mRNA

NCBI chr 8:62,876,003...62,905,080
Ensembl chr 8:62,876,003...62,905,042

G

acetyl-CoA acetyltransferase 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ACAT2 mRNA

NCBI chr 1:50,100,840...50,118,886
Ensembl chr 1:50,100,817...50,135,095

G

acyl-CoA binding domain containing 3

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of ACBD3 mRNA
Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of ACBD3 mRNA]

PMID:22206623 PMID:25629700

NCBI chr13:94,987,643...95,016,356
Ensembl chr13:94,987,541...95,016,355

G

acyl-CoA binding domain containing 4

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of ACBD4 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ACBD4 mRNA

PMID:22206623 PMID:25629700

NCBI chr10:88,548,146...88,558,588
Ensembl chr10:88,548,158...88,558,587

G

acyl-CoA binding domain containing 5

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ACBD5 gene
[Ethanol co-treated with Folic Acid] results in increased expression of ACBD5 mRNA

PMID:20938992 PMID:23378141

NCBI chr17:90,114,250...90,156,286
Ensembl chr17:90,114,375...90,156,286

G

acyl-CoA binding domain containing 6

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ACBD6 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ACBD6 gene

PMID:20938992 PMID:22206623

NCBI chr13:70,277,036...70,412,598
Ensembl chr13:70,277,057...70,412,597

G

angiotensin I converting enzyme

multiple interactions
increases expression

EXP
ISO

Enalapril promotes the reaction [Folic Acid results in increased expression of ACE mRNA]
Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of ACE mRNA]

PMID:15728788 PMID:22206623

NCBI chr10:91,410,129...91,430,246
Ensembl chr10:91,409,819...91,430,942

G

alkaline ceramidase 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ACER2 mRNA

NCBI chr 5:106,437,773...106,488,572
Ensembl chr 5:106,437,796...106,488,583

G

alkaline ceramidase 3

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of ACER3 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ACER3 mRNA

PMID:21867686 PMID:22206623

NCBI chr 1:161,915,397...162,017,802
Ensembl chr 1:161,915,397...162,017,912

G

acetylcholinesterase

multiple interactions
decreases expression

ISO

Folic Acid inhibits the reaction [MTHFR gene polymorphism results in increased activity of ACHE protein]
Folic Acid results in decreased expression of ACHE mRNA

PMID:16375580 PMID:25629700

NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410

G

atypical chemokine receptor 1

decreases expression

ISO

Folic Acid results in decreased expression of ACKR1 mRNA

NCBI chr13:88,314,735...88,316,354
Ensembl chr13:88,293,188...88,317,807

G

atypical chemokine receptor 3

affects expression
decreases expression

ISO

Folic Acid affects the expression of ACKR3 mRNA
Folic Acid results in decreased expression of CXCR7 mRNA

PMID:17320366 PMID:25629700

NCBI chr 9:98,247,300...98,258,877
Ensembl chr 9:98,246,605...98,260,214

G

atypical chemokine receptor 4

affects expression

ISO

Folic Acid affects the expression of ACKR4 mRNA

NCBI chr 8:113,595,325...113,599,762
Ensembl chr 8:113,595,293...113,602,372

G

ATP citrate lyase

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ACLY gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ACLY mRNA]

PMID:20938992 PMID:22206623

NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,912,402...85,963,631

G

aconitase 1

decreases expression

ISO

Folic Acid results in decreased expression of ACO1 mRNA

NCBI chr 5:60,055,895...60,111,920
Ensembl chr 5:60,055,866...60,112,600

G

aconitase 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ACO2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ACO2 gene

PMID:20938992 PMID:22206623

NCBI chr 7:115,265,816...115,308,931
Ensembl chr 7:115,265,791...115,308,892

G

acyl-CoA thioesterase 1

multiple interactions

ISO

[Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in decreased expression of ACOT1 mRNA

NCBI chr 6:109,367,274...109,375,268
Ensembl chr 6:109,367,268...109,380,749

G

acyl-CoA thioesterase 11

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ACOT11 mRNA

NCBI chr 5:126,756,255...126,804,526
Ensembl chr 5:126,756,255...126,804,507

G

acyl-CoA thioesterase 13

multiple interactions
increases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ACOT13 mRNA
Folic Acid results in increased expression of ACOT13 mRNA

PMID:22206623 PMID:25629700

NCBI chr17:40,668,404...40,680,876
Ensembl chr17:40,668,316...40,680,876

G

acyl-CoA thioesterase 2

multiple interactions
decreases expression

ISO

[Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of ACOT2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ACOT2 mRNA
Folic Acid results in decreased expression of ACOT2 mRNA

PMID:20938992 PMID:25629700 PMID:29127188

NCBI chr 6:109,341,426...109,352,818
Ensembl chr 6:109,342,646...109,350,502

G

acyl-CoA thioesterase 3

increases expression

ISO

Folic Acid results in increased expression of ACOT3 mRNA

NCBI chr 6:109,413,617...109,419,840
Ensembl chr 6:109,413,534...109,421,427
Ensembl chr 6:109,413,534...109,421,427

G

acyl-CoA thioesterase 6

decreases expression

ISO

Folic Acid results in decreased expression of ACOT6 mRNA

NCBI chr 6:109,463,513...109,472,587

G

acyl-CoA thioesterase 7

multiple interactions
increases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ACOT7 mRNA
Folic Acid results in increased expression of ACOT7 mRNA

PMID:22206623 PMID:25629700

NCBI chr 5:167,969,284...168,062,033
Ensembl chr 5:167,968,895...168,062,033

G

acyl-CoA thioesterase 8

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ACOT8 mRNA

NCBI chr 3:173,950,530...173,962,188
Ensembl chr 3:173,950,531...173,962,570

G

acyl-CoA thioesterase 9

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ACOT9 mRNA; [Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of ACOT9 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ACOT9 mRNA
Folic Acid results in decreased expression of ACOT9 mRNA

PMID:20938992 PMID:22206623 PMID:25629700 PMID:29127188

NCBI chr X:43,922,943...43,973,311
Ensembl chr X:43,914,923...43,973,205

G

acyl-CoA oxidase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ACOX1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ACOX1 mRNA

PMID:20938992 PMID:22206623 PMID:22872676

NCBI chr10:101,905,083...101,930,136
Ensembl chr10:101,905,083...101,930,136

G

acyl-CoA oxidase 3, pristanoyl

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ACOX3 mRNA
Folic Acid results in decreased expression of ACOX3 mRNA

PMID:22206623 PMID:25629700

NCBI chr14:79,358,604...79,405,160
Ensembl chr14:79,302,042...79,400,881

G

acid phosphatase 1

decreases expression

ISO

Folic Acid results in decreased expression of ACP1 mRNA

NCBI chr 6:53,233,937...53,249,576
Ensembl chr 6:53,233,948...53,251,959

G

acid phosphatase 2, lysosomal

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ACP2 mRNA]

NCBI chr 3:97,630,654...97,642,601
Ensembl chr 3:97,631,326...97,642,565

G

acid phosphatase 6, lysophosphatidic

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ACP6 mRNA

NCBI chr 2:187,400,786...187,421,877
Ensembl chr 2:187,349,186...187,422,743

G

acrosin

decreases expression

ISO

Folic Acid results in decreased expression of ACR mRNA

NCBI chr 7:122,517,910...122,524,110
Ensembl chr 7:122,517,934...122,524,087

G

acyl-CoA synthetase family member 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ACSF2 mRNA

NCBI chr10:80,001,389...80,043,796
Ensembl chr10:80,001,389...80,045,050

G

acyl-CoA synthetase long-chain family member 4

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ACSL4 mRNA

NCBI chr X:110,739,633...110,803,416
Ensembl chr X:110,739,648...110,803,261

G

acyl-CoA synthetase long-chain family member 5

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ACSL5 mRNA]

NCBI chr 1:264,294,851...264,341,943
Ensembl chr 1:264,294,864...264,341,943

G

acyl-CoA synthetase medium-chain family member 3

multiple interactions
increases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ACSM3 mRNA
Folic Acid results in increased expression of ACSM3 mRNA

PMID:22206623 PMID:25629700

NCBI chr 1:183,564,652...183,591,328
Ensembl chr 1:183,564,635...183,591,437

G

acyl-CoA synthetase medium-chain family member 5

decreases expression

ISO

Folic Acid results in decreased expression of ACSM5 mRNA

NCBI chr 1:183,302,241...183,328,175
Ensembl chr 1:183,294,105...183,329,925

G

acyl-CoA synthetase short-chain family member 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ACSS1 mRNA; [Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of ACSS1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ACSS1 mRNA

PMID:20938992 PMID:22206623 PMID:29127188

NCBI chr 3:159,910,809...159,960,748
Ensembl chr 3:159,910,809...159,960,748

G

acyl-CoA synthetase short-chain family member 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ACSS2 mRNA

NCBI chr 3:164,464,124...164,507,607
Ensembl chr 3:164,464,055...164,519,830

G

actin, alpha 1, skeletal muscle

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ACTA1 mRNA; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ACTA1 mRNA]
Folic Acid results in decreased expression of ACTA1 mRNA

PMID:20938992 PMID:21867686 PMID:22206623

NCBI chr19:68,781,168...68,784,194
Ensembl chr19:68,781,168...68,786,178

G

actin alpha 2, smooth muscle

multiple interactions
increases expression
decreases expression
affects expression

ISO
EXP

6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride inhibits the reaction [Folic Acid results in increased expression of ACTA2 protein]; 6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride promotes the reaction [pyrazolanthrone inhibits the reaction [Folic Acid results in increased expression of ACTA2 protein]]; [1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ACTA2 mRNA; [Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ACTA2 mRNA; [Folic Acid deficiency results in increased abundance of Homocysteine] which results in increased expression of ACTA2 mRNA; [Folic Acid deficiency results in increased abundance of Homocysteine] which results in increased expression of ACTA2 protein; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ACTA2 mRNA; celastrol inhibits the reaction [Folic Acid results in increased expression of ACTA2 protein]; CYBB mutant form inhibits the reaction [[Folic Acid deficiency results in increased abundance of Homocysteine] which results in increased expression of ACTA2 mRNA]; CYBB mutant form inhibits the reaction [[Folic Acid deficiency results in increased abundance of Homocysteine] which results in increased expression of ACTA2 protein]; CYBB mutant form inhibits the reaction [Folic Acid deficiency results in increased expression of ACTA2 protein]; Decitabine inhibits the reaction [Folic Acid results in increased expression of ACTA2 mRNA]; Decitabine inhibits the reaction [Folic Acid results in increased expression of ACTA2 protein]; pyrazolanthrone inhibits the reaction [Folic Acid results in increased expression of ACTA2 protein]; pyrazolanthrone promotes the reaction [6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride inhibits the reaction [Folic Acid results in increased expression of ACTA2 protein]]; SR 144528 inhibits the reaction [celastrol inhibits the reaction [Folic Acid results in increased expression of ACTA2 protein]]; trichostatin A inhibits the reaction [Folic Acid results in increased expression of ACTA2 mRNA]; trichostatin A inhibits the reaction [Folic Acid results in increased expression of ACTA2 protein]
[Methionine co-treated with Betaine co-treated with Choline co-treated with Folic Acid] inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 mRNA]
Folic Acid results in decreased expression of ACTA2 protein
Folic Acid affects the expression of ACTA2 mRNA
Folic Acid deficiency results in increased expression of ACTA2 protein; Folic Acid results in increased expression of ACTA2 mRNA; Folic Acid results in increased expression of ACTA2 protein

PMID:17320366 PMID:20938992 PMID:21647593 PMID:22206623 PMID:23439872 More...

NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503

G

actin, alpha, cardiac muscle 1

affects expression
increases expression
multiple interactions

ISO

Folic Acid affects the expression of ACTC1 mRNA
Folic Acid results in increased expression of ACTC1 mRNA
[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ACTC1 mRNA

PMID:17320366 PMID:20938992 PMID:34742744

NCBI chr 3:121,266,291...121,271,827
Ensembl chr 3:121,266,291...121,271,827

G

actin, gamma 1

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ACTG1 mRNA]

NCBI chr10:106,118,106...106,120,951
Ensembl chr10:106,118,108...106,120,951

G

actin gamma 2, smooth muscle

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ACTG2 mRNA

NCBI chr 4:117,579,513...117,604,379
Ensembl chr 4:117,579,514...117,604,295

G

actin-like 6A

multiple interactions
decreases expression

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ACTL6A mRNA]
Folic Acid results in decreased expression of ACTL6A mRNA

PMID:22206623 PMID:25629700

NCBI chr 2:117,413,206...117,436,758
Ensembl chr 2:117,418,601...117,436,754

G

actin-like 7a

decreases expression

ISO

Folic Acid results in decreased expression of ACTL7A mRNA

NCBI chr 5:76,242,201...76,245,647
Ensembl chr 5:76,240,427...76,247,023

G

actinin, alpha 1

multiple interactions
decreases expression

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ACTN1 mRNA]
Folic Acid results in decreased expression of ACTN1 mRNA

PMID:22206623 PMID:25629700

NCBI chr 6:104,731,485...104,826,312
Ensembl chr 6:104,731,485...104,826,172

G

actinin alpha 2

decreases expression

ISO

Folic Acid results in decreased expression of ACTN2 mRNA

NCBI chr17:62,835,055...62,902,331
Ensembl chr17:62,812,988...62,903,552

G

actin related protein 10

increases expression
multiple interactions

ISO

Folic Acid results in increased expression of ACTR10 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ACTR10 mRNA

PMID:22206623 PMID:25629700

NCBI chr 6:95,182,082...95,208,325
Ensembl chr 6:95,182,111...95,209,021

G

actin related protein 1A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ACTR1A mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ACTR1A gene

PMID:20938992 PMID:22206623

NCBI chr 1:255,179,241...255,199,009
Ensembl chr 1:255,179,242...255,199,459

G

actin related protein 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ACTR2 mRNA

NCBI chr14:98,500,119...98,535,092
Ensembl chr14:98,500,138...98,541,998

G

actin related protein 3

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of ACTR3 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ACTR3 mRNA

PMID:22206623 PMID:25629700

NCBI chr13:39,353,413...39,396,509
Ensembl chr13:39,353,079...39,396,711

G

actin related protein 5

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ACTR5 gene

NCBI chr 3:167,702,299...167,715,736
Ensembl chr 3:167,702,482...167,715,730

G

actin related protein 6

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ACTR6 mRNA

NCBI chr 7:26,037,574...26,058,362
Ensembl chr 7:26,037,574...26,060,604

G

actin related protein 8

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ACTR8 mRNA

NCBI chr16:5,170,649...5,192,883
Ensembl chr16:5,167,237...5,186,180

G

actin-related protein T2

decreases expression

ISO

Folic Acid results in decreased expression of ACTRT2 mRNA

NCBI chr 5:170,518,470...170,519,870
Ensembl chr 5:170,518,165...170,521,164

G

activin A receptor type 1

decreases expression

ISO

Folic Acid results in decreased expression of ACVR1 mRNA

NCBI chr 3:63,387,378...63,506,980
Ensembl chr 3:63,387,381...63,477,884

G

activin A receptor type 1B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ACVR1B mRNA

NCBI chr 7:134,164,987...134,208,389
Ensembl chr 7:134,164,991...134,208,388

G

activin A receptor type 1C

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ACVR1C gene

NCBI chr 3:63,224,322...63,301,252
Ensembl chr 3:63,227,559...63,301,205

G

activin A receptor type 2A

decreases expression

ISO

Folic Acid results in decreased expression of ACVR2A mRNA

NCBI chr 3:53,614,143...53,701,933
Ensembl chr 3:53,614,171...53,701,941

G

activin A receptor type 2B

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ACVR2B gene

NCBI chr 8:128,016,589...128,056,193
Ensembl chr 8:128,016,526...128,048,171

G

aminoacylase 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ACY3 mRNA

NCBI chr 1:210,709,238...210,715,258
Ensembl chr 1:210,709,294...210,715,633

G

acylphosphatase 1

decreases expression

ISO

Folic Acid results in decreased expression of ACYP1 mRNA

NCBI chr 6:110,650,213...110,663,404
Ensembl chr 6:110,650,213...110,663,612

G

adenosine deaminase

increases expression

ISO

Folic Acid deficiency results in increased expression of ADA protein

NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:172,818,176...172,842,293

G

ADAM metallopeptidase domain 11

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ADAM11 mRNA; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of ADAM11 mRNA]

PMID:20938992 PMID:22206623

NCBI chr10:88,224,185...88,242,865
Ensembl chr10:88,224,347...88,242,864

G

ADAM metallopeptidase domain 12

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ADAM12 gene
Folic Acid results in decreased expression of ADAM12 mRNA

PMID:20938992 PMID:21867686

NCBI chr 1:198,116,968...198,443,680
Ensembl chr 1:198,116,975...198,447,552

G

ADAM metallopeptidase domain 15

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ADAM15 mRNA

NCBI chr 2:177,052,363...177,062,879
Ensembl chr 2:177,052,363...177,062,849

G

ADAM metallopeptidase domain 18

increases expression

ISO

Folic Acid results in increased expression of ADAM18 mRNA

NCBI chr16:74,054,974...74,127,861
Ensembl chr16:74,055,008...74,127,864

G

ADAM metallopeptidase domain 19

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ADAM19 mRNA

NCBI chr10:30,992,713...31,084,455
Ensembl chr10:30,992,754...31,084,455

G

ADAM metallopeptidase domain 2

decreases expression

ISO

Folic Acid results in decreased expression of ADAM2 mRNA

NCBI chr15:44,418,191...44,459,570
Ensembl chr15:44,418,199...44,459,516

G

ADAM metallopeptidase domain 24

increases expression

ISO

Folic Acid results in increased expression of ADAM24 mRNA

NCBI chr16:58,281,748...58,287,735
Ensembl chr16:58,281,748...58,287,735

G

ADAM metallopeptidase domain 30

increases expression

ISO

Folic Acid results in increased expression of ADAM30 mRNA

NCBI chr 2:188,440,918...188,444,358
Ensembl chr 2:188,440,918...188,444,358

G

ADAM metallopeptidase domain 33

decreases expression

ISO

Folic Acid results in decreased expression of ADAM33 mRNA

NCBI chr 3:138,715,428...138,736,392
Ensembl chr 3:138,724,046...138,736,347

G

ADAM metallopeptidase domain 3A

increases expression

ISO

Folic Acid results in increased expression of ADAM3 mRNA

NCBI chr16:74,002,566...74,052,579
Ensembl chr16:74,002,410...74,052,578

G

ADAM metallopeptidase domain 8

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ADAM8 mRNA

NCBI chr 1:204,206,206...204,218,988
Ensembl chr 1:204,206,199...204,218,485

G

ADAM metallopeptidase domain 9

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ADAM9 mRNA

NCBI chr16:73,725,186...73,804,284
Ensembl chr16:73,725,114...73,804,646

G

ADAM-like, decysin 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ADAMDEC1 mRNA

NCBI chr15:47,076,011...47,097,065
Ensembl chr15:47,076,019...47,097,065

G

ADAM metallopeptidase with thrombospondin type 1 motif, 1

decreases expression

ISO

Folic Acid results in decreased expression of ADAMTS1 mRNA

NCBI chr11:38,418,565...38,427,384
Ensembl chr11:38,418,101...38,427,390

G

ADAM metallopeptidase with thrombospondin type 1 motif, 12

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ADAMTS12 mRNA

NCBI chr 2:61,759,975...62,054,716
Ensembl chr 2:61,759,987...62,054,716

G

ADAM metallopeptidase with thrombospondin type 1 motif, 15

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ADAMTS15 gene; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of ADAMTS15; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ADAMTS15 mRNA

NCBI chr 8:37,566,064...37,589,446
Ensembl chr 8:37,566,065...37,589,446

G

ADAM metallopeptidase with thrombospondin type 1 motif, 16

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ADAMTS16 mRNA

NCBI chr 1:34,258,899...34,388,952
Ensembl chr 1:34,258,899...34,388,952

G

ADAM metallopeptidase with thrombospondin type 1 motif, 18

decreases expression

ISO

Folic Acid results in decreased expression of ADAMTS18 mRNA

NCBI chr19:58,596,095...58,749,239
Ensembl chr19:58,597,761...58,749,138

G

ADAM metallopeptidase with thrombospondin type 1 motif, 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ADAMTS2 mRNA

NCBI chr10:35,422,030...35,627,483
Ensembl chr10:35,422,030...35,627,483

G

ADAM metallopeptidase with thrombospondin type 1, motif 3

decreases expression

ISO

Folic Acid results in decreased expression of ADAMTS3 mRNA

NCBI chr14:18,515,249...18,721,887
Ensembl chr14:18,515,249...18,721,887

G

ADAM metallopeptidase with thrombospondin type 1 motif, 7

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ADAMTS7 mRNA

NCBI chr 8:99,584,529...99,624,132
Ensembl chr 8:99,584,529...99,624,132

G

ADAM metallopeptidase with thrombospondin type 1 motif, 9

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ADAMTS9 mRNA
Folic Acid results in decreased expression of ADAMTS9 mRNA

PMID:20938992 PMID:25629700

NCBI chr 4:126,847,726...127,019,924
Ensembl chr 4:126,847,729...127,019,876

G

ADAMTS-like 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ADAMTSL2 mRNA

NCBI chr 3:30,795,882...30,832,635
Ensembl chr 3:30,802,700...30,832,635

G

ADAMTS-like 5

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ADAMTSL5 gene

NCBI chr 7:10,013,306...10,021,924
Ensembl chr 7:10,013,929...10,021,924

G

ArfGAP with dual PH domains 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ADAP1 mRNA

NCBI chr12:20,438,091...20,489,961
Ensembl chr12:20,438,063...20,495,020

G

ArfGAP with dual PH domains 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ADAP2 gene

NCBI chr10:65,635,891...65,665,019
Ensembl chr10:65,622,434...65,664,022

G

adenosine deaminase, RNA-specific, B1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ADARB1 mRNA

NCBI chr20:11,222,171...11,350,416
Ensembl chr20:11,222,164...11,350,415

G

aarF domain containing kinase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ADCK1 mRNA

NCBI chr 6:113,005,333...113,107,960
Ensembl chr 6:113,008,111...113,132,359

G

aarF domain containing kinase 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ADCK2 mRNA

NCBI chr 4:69,315,633...69,328,535
Ensembl chr 4:69,315,635...69,329,502

G

aarF domain containing kinase 5

increases expression

ISO

Folic Acid results in increased expression of ADCK5 mRNA

NCBI chr 7:110,182,275...110,200,088
Ensembl chr 7:110,181,981...110,200,088

G

adenylate cyclase 10

decreases expression

ISO

Folic Acid results in decreased expression of ADCY10 mRNA

NCBI chr13:80,280,595...80,366,939
Ensembl chr13:80,284,295...80,366,926

G

adenylate cyclase 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ADCY2 mRNA

NCBI chr 1:36,204,054...36,650,645
Ensembl chr 1:36,204,054...36,650,645

G

adenylate cyclase 3

multiple interactions
affects expression
affects methylation
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ADCY3 mRNA
Folic Acid affects the expression of ADCY3 mRNA
Folic Acid affects the methylation of ADCY3 gene
Folic Acid results in increased expression of ADCY3 mRNA

PMID:20938992 PMID:25629700 PMID:29986310

NCBI chr 6:32,819,602...32,923,174
Ensembl chr 6:32,843,961...32,923,173

G

adenylate cyclase 5

decreases expression

ISO

Folic Acid results in decreased expression of ADCY5 mRNA

NCBI chr11:78,976,861...79,123,343
Ensembl chr11:78,976,861...79,123,343

G

adenylate cyclase 6

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ADCY6 mRNA]

NCBI chr 7:131,621,860...131,642,923
Ensembl chr 7:131,621,860...131,642,770

G

adenylate cyclase 7

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ADCY7 mRNA
Folic Acid results in decreased expression of ADCY7 mRNA

PMID:20938992 PMID:25629700

NCBI chr19:34,913,154...34,972,366
Ensembl chr19:34,914,322...34,936,743

G

adenylate cyclase 8

affects expression

ISO

Folic Acid affects the expression of ADCY8 mRNA

NCBI chr 7:98,306,434...98,555,687
Ensembl chr 7:98,306,464...98,555,038

G

adenylate cyclase 9

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ADCY9 mRNA]

NCBI chr10:11,645,373...11,768,462
Ensembl chr10:11,645,282...11,765,792

G

adenylate cyclase activating polypeptide 1

decreases expression

ISO

Folic Acid results in decreased expression of ADCYAP1 mRNA

NCBI chr 9:120,550,236...120,569,096
Ensembl chr 9:120,550,328...120,556,383

G

adducin 3

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ADD3 gene

NCBI chr 1:262,152,722...262,260,504
Ensembl chr 1:262,154,996...262,260,504

G

adhesion G protein-coupled receptor A1

decreases expression

ISO

Folic Acid results in decreased expression of ADGRA1 mRNA

NCBI chr 1:204,059,218...204,102,869
Ensembl chr 1:204,059,367...204,102,869

G

adhesion G protein-coupled receptor A3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ADGRA3 mRNA

NCBI chr14:65,085,418...65,188,949
Ensembl chr14:65,087,380...65,188,959

G

adhesion G protein-coupled receptor B1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ADGRB1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ADGRB1 gene

PMID:20938992 PMID:22206623

NCBI chr 7:108,293,681...108,365,892
Ensembl chr 7:108,293,818...108,365,870

G

adhesion G protein-coupled receptor B2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ADGRB2 gene

NCBI chr 5:147,581,573...147,646,726
Ensembl chr 5:147,611,580...147,646,726

G

adhesion G protein-coupled receptor D1

decreases expression

ISO

Folic Acid results in decreased expression of ADGRD1 mRNA

NCBI chr12:33,124,981...33,239,778
Ensembl chr12:33,125,915...33,272,509

G

adhesion G protein-coupled receptor E1

multiple interactions
increases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ADGRE1 mRNA; Metformin inhibits the reaction [Folic Acid results in increased expression of ADGRE1 mRNA]

PMID:22206623 PMID:29380373 PMID:34619300

NCBI chr 9:2,329,398...2,484,959
Ensembl chr 9:2,329,438...2,484,959

G

adhesion G protein-coupled receptor G2

multiple interactions
decreases expression

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of ADGRG2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ADGRG2 mRNA
Folic Acid results in decreased expression of ADGRG2 mRNA

PMID:20938992 PMID:21867686 PMID:33549593

NCBI chr X:38,106,067...38,231,286
Ensembl chr X:38,106,067...38,231,331

G

adhesion G protein-coupled receptor G3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ADGRG3 mRNA

NCBI chr19:9,978,450...10,007,145
Ensembl chr19:9,978,514...10,007,238

G

adhesion G protein-coupled receptor G6

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ADGRG6 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ADGRG6 gene

NCBI chr 1:10,633,004...10,774,685
Ensembl chr 1:10,631,829...10,774,023

G

adhesion G protein-coupled receptor L1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ADGRL1 mRNA

NCBI chr19:41,107,162...41,148,752
Ensembl chr19:41,109,117...41,148,896

G

adhesion G protein-coupled receptor L2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ADGRL2 gene; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of and results in decreased expression of ADGRL2

NCBI chr 2:240,356,176...240,987,246
Ensembl chr 2:240,356,177...240,855,933

G

adhesion G protein-coupled receptor L3

decreases expression

ISO

Folic Acid results in decreased expression of LPHN3 mRNA

NCBI chr14:26,690,891...27,458,132
Ensembl chr14:26,722,194...27,280,418

G

adhesion G protein-coupled receptor L4

decreases expression

ISO

Folic Acid results in decreased expression of ELTD1 mRNA

NCBI chr 2:243,014,927...243,117,226
Ensembl chr 2:243,014,796...243,117,222

G

adhesion G protein-coupled receptor V1

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ADGRV1 mRNA
Folic Acid results in increased expression of ADGRV1 mRNA

PMID:20938992 PMID:21867686

NCBI chr 2:13,067,149...13,647,407
Ensembl chr 2:13,067,150...13,647,372

G

alcohol dehydrogenase 1C (class I), gamma polypeptide

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ADH1 mRNA

NCBI chr 2:229,470,703...229,482,291
Ensembl chr 2:229,470,703...229,482,291

G

alcohol dehydrogenase 5 (class III), chi polypeptide

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ADH5 gene
Folic Acid results in decreased expression of ADH5 mRNA

PMID:20938992 PMID:25629700

NCBI chr 2:229,648,557...229,660,964
Ensembl chr 2:229,648,501...229,665,232

G

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ADH7 mRNA

NCBI chr 2:229,422,125...229,436,584
Ensembl chr 2:229,421,252...229,436,691

G

alcohol dehydrogenase, iron containing, 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ADHFE1 mRNA
[Ethanol co-treated with Folic Acid] results in increased expression of ADHFE1 mRNA

PMID:20938992 PMID:23378141

NCBI chr 5:14,488,784...14,515,405
Ensembl chr 5:14,488,788...14,515,835

G

acireductone dioxygenase 1

decreases expression

ISO

Folic Acid results in decreased expression of ADI1 mRNA

NCBI chr 6:51,035,267...51,042,229
Ensembl chr 6:51,034,931...51,042,855

G

adiponectin receptor 1

decreases expression

ISO

Folic Acid results in decreased expression of ADIPOR1 mRNA

NCBI chr13:48,411,438...48,431,251
Ensembl chr13:48,411,826...48,431,255

G

adiponectin receptor 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ADIPOR2 mRNA

NCBI chr 4:154,195,440...154,261,141
Ensembl chr 4:154,172,567...154,231,666

G

adenosine kinase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ADK mRNA

NCBI chr15:2,912,543...3,295,745
Ensembl chr15:2,912,544...3,295,745

G

adrenomedullin

multiple interactions

ISO

[Ethanol co-treated with Folic Acid] results in increased expression of ADM mRNA

NCBI chr 1:174,164,178...174,182,372
Ensembl chr 1:174,178,773...174,182,371

G

ADNP homeobox 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ADNP2 mRNA

NCBI chr18:75,846,860...75,871,638
Ensembl chr18:75,847,165...75,903,317

G

adenosine A1 receptor

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ADORA1 mRNA

NCBI chr13:48,210,922...48,247,826
Ensembl chr13:48,213,273...48,247,190

G

adenosine A2a receptor

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of ADORA2A mRNA]

NCBI chr20:13,315,270...13,332,802
Ensembl chr20:13,315,270...13,332,802

G

adenosine A2B receptor

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ADORA2B mRNA

NCBI chr10:47,439,712...47,456,092
Ensembl chr10:47,439,701...47,456,091

G

ADP-ribosylarginine hydrolase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ADPRH mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ADPRH mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ADPRH gene

PMID:20938992 PMID:22206623

NCBI chr11:75,805,347...75,811,686
Ensembl chr11:75,805,310...75,812,452

G

ADP-ribosylhydrolase like 1

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of ADPRHL1 mRNA]

NCBI chr16:82,985,355...83,017,240

G

ADP-ribosylserine hydrolase

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ADPRS mRNA]

NCBI chr 5:143,898,542...143,903,816
Ensembl chr 5:143,898,542...143,903,816

G

adrenoceptor alpha 1B

increases expression

ISO

Folic Acid results in increased expression of ADRA1B mRNA

NCBI chr10:28,756,461...28,874,831
Ensembl chr10:28,756,461...28,814,347

G

adrenoceptor alpha 2A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ADRA2A mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ADRA2A gene

PMID:20938992 PMID:22206623

NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:263,065,278...263,069,871

G

adrenoceptor alpha 2B

decreases expression

ISO

Folic Acid results in decreased expression of ADRA2B mRNA

NCBI chr 3:135,038,481...135,042,527
Ensembl chr 3:135,038,474...135,042,525

G

adrenoceptor beta 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ADRB2 mRNA

NCBI chr18:57,912,760...57,914,802
Ensembl chr18:57,911,348...57,914,803

G

adrenoceptor beta 3

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ADRB3 gene
Folic Acid results in increased expression of ADRB3 mRNA

PMID:20938992 PMID:25629700

NCBI chr16:71,544,603...71,547,410
Ensembl chr16:71,542,567...71,547,420

G

adenylosuccinate lyase

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ADSL mRNA]

NCBI chr 7:114,359,440...114,383,618
Ensembl chr 7:114,359,440...114,384,872

G

adenylosuccinate synthase 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ADSS1 gene
Folic Acid results in decreased expression of ADSS1 mRNA

PMID:20938992 PMID:25629700

NCBI chr 6:137,500,549...137,523,087
Ensembl chr 6:137,501,001...137,523,086

G

adenylosuccinate synthase 2

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ADSS2 mRNA
Folic Acid results in decreased expression of ADSS2 mRNA

PMID:22206623 PMID:25629700

NCBI chr13:92,301,302...92,331,638
Ensembl chr13:92,301,302...92,331,638

G

AE binding protein 1

increases expression

ISO

Folic Acid results in increased expression of AEBP1 mRNA

NCBI chr14:84,951,577...84,962,840
Ensembl chr14:84,952,822...84,962,843

G

AE binding protein 2

decreases expression

ISO

Folic Acid results in decreased expression of AEBP2 mRNA

NCBI chr 4:175,258,286...175,297,149
Ensembl chr 4:175,258,887...175,326,422

G

apoptosis enhancing nuclease

multiple interactions
increases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of AEN mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of AEN gene
Folic Acid results in increased expression of AEN mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr 1:142,224,499...142,233,902
Ensembl chr 1:142,224,493...142,233,898

G

actin filament associated protein 1

affects expression

ISO

Folic Acid affects the expression of AFAP1 mRNA

NCBI chr14:78,967,961...79,081,032
Ensembl chr14:78,967,961...79,080,939

G

actin filament associated protein 1-like 1

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of AFAP1L1 mRNA
Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of AFAP1L1 mRNA]

PMID:21867686 PMID:22206623

NCBI chr18:57,454,120...57,514,584
Ensembl chr18:57,454,121...57,514,480

G

actin filament associated protein 1-like 2

decreases expression

ISO

Folic Acid results in decreased expression of AFAP1L2 mRNA

NCBI chr 1:265,969,368...266,065,951
Ensembl chr 1:265,969,368...266,065,943

G

ALF transcription elongation factor 1

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AFF1 mRNA
Folic Acid results in decreased expression of AFF1 mRNA

PMID:22206623 PMID:25629700

NCBI chr14:6,165,864...6,328,848
Ensembl chr14:6,169,562...6,328,879

G

ALF transcription elongation factor 3

increases expression

ISO

Folic Acid results in increased expression of AFF3 mRNA

NCBI chr 9:47,894,903...48,352,380
Ensembl chr 9:47,894,903...48,353,000

G

ALF transcription elongation factor 4

decreases expression

ISO

Folic Acid results in decreased expression of AFF4 mRNA

NCBI chr10:37,998,319...38,080,580
Ensembl chr10:37,999,579...38,080,580

G

AFG2 AAA ATPase homolog A

decreases expression

ISO

Folic Acid results in decreased expression of AFG2A mRNA

NCBI chr 2:122,234,619...122,425,808
Ensembl chr 2:122,234,738...122,425,808

G

AFG3 like matrix AAA peptidase subunit 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of AFG3L2 mRNA

NCBI chr18:63,224,163...63,269,000
Ensembl chr18:63,224,163...63,269,000

G

alpha-fetoprotein

multiple interactions

ISO
EXP

[Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of AFP mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AFP mRNA
[Folic Acid deficiency co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of AFP protein

PMID:19566968 PMID:20938992 PMID:29127188

NCBI chr14:17,857,584...17,875,645
Ensembl chr14:17,857,584...17,875,649

G

aftiphilin

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of AFTPH mRNA

NCBI chr14:99,072,761...99,127,006
Ensembl chr14:99,072,761...99,126,727

G

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of AGAP1 mRNA]

NCBI chr 9:97,487,382...97,922,870
Ensembl chr 9:97,487,406...97,922,870

G

ArfGAP with GTPase domain, ankyrin repeat and PH domain 2

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of AGAP2 gene
Folic Acid results in increased expression of AGAP2 mRNA

PMID:20938992 PMID:25629700

NCBI chr 7:64,782,618...64,799,624
Ensembl chr 7:64,782,612...64,799,640

G

AGBL carboxypeptidase 3

increases expression

ISO

Folic Acid results in increased expression of AGBL3 mRNA

NCBI chr 4:64,416,139...64,498,987
Ensembl chr 4:64,421,397...64,498,985

G

AGBL carboxypeptidase 4

decreases expression

ISO

Folic Acid results in decreased expression of AGBL4 mRNA

NCBI chr 5:130,483,551...131,762,906

G

angiogenic factor with G patch and FHA domains 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of AGGF1 mRNA

NCBI chr 2:28,354,073...28,380,794
Ensembl chr 2:28,354,073...28,380,759

G

amylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of AGL mRNA]

NCBI chr 2:207,389,949...207,445,959
Ensembl chr 2:207,389,949...207,445,724

G

alkylglycerol monooxygenase

decreases expression

ISO

Folic Acid results in decreased expression of AGMO mRNA

NCBI chr 6:59,713,495...60,044,851
Ensembl chr 6:59,713,467...60,044,854

G

argonaute RISC component 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of AGO1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of AGO1 gene

NCBI chr 5:144,006,618...144,064,740
Ensembl chr 5:144,006,618...144,041,624

G

argonaute RISC catalytic component 2

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AGO2 mRNA
Folic Acid results in decreased expression of AGO2 mRNA

PMID:22206623 PMID:25629700

NCBI chr 7:106,907,209...106,994,124
Ensembl chr 7:106,918,125...106,993,980

G

argonaute RISC component 4

decreases expression

ISO

Folic Acid results in decreased expression of AGO4 mRNA

NCBI chr 5:144,064,949...144,110,422
Ensembl chr 5:144,064,949...144,110,402

G

1-acylglycerol-3-phosphate O-acyltransferase 4

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AGPAT4 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AGPAT4 mRNA

PMID:20938992 PMID:22206623

NCBI chr 1:51,075,081...51,181,548
Ensembl chr 1:51,075,081...51,180,976

G

anterior gradient 2, protein disulphide isomerase family member

increases expression
multiple interactions

ISO

Folic Acid results in increased expression of AGR2 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AGR2 mRNA

PMID:17868486 PMID:22206623

NCBI chr 6:58,435,908...58,456,678
Ensembl chr 6:58,435,908...58,456,677

G

agrin

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AGRN mRNA

NCBI chr 5:172,031,528...172,064,429
Ensembl chr 5:172,031,528...172,064,539

G

angiotensinogen

multiple interactions
decreases expression
increases localization

EXP
ISO

AGT protein promotes the reaction [Folic Acid results in increased expression of PTHLH protein]; candesartan inhibits the reaction [Folic Acid results in increased localization of [AGT protein binds to AGTR1A protein]]; Folic Acid results in increased localization of [AGT protein binds to AGTR1A protein]; Losartan inhibits the reaction [Folic Acid results in increased localization of [AGT protein binds to AGTR1A protein]]; Losartan inhibits the reaction [Folic Acid results in increased localization of AGT protein]; PTHLH protein promotes the reaction [Folic Acid results in increased expression of AGT protein]
Folic Acid affects the reaction [HPH1 protein affects the susceptibility to AGT protein]; Folic Acid inhibits the reaction [AGT protein results in decreased expression of CBS mRNA]; Folic Acid inhibits the reaction [AGT protein results in decreased expression of CBS protein]; Folic Acid inhibits the reaction [AGT protein results in decreased expression of CTH mRNA]; Folic Acid inhibits the reaction [AGT protein results in decreased expression of CTH protein]; Folic Acid inhibits the reaction [AGT protein results in decreased expression of MTHFR mRNA]; Folic Acid inhibits the reaction [AGT protein results in decreased expression of MTHFR protein]; Folic Acid inhibits the reaction [AGT protein results in decreased expression of NOS3 protein]; Folic Acid inhibits the reaction [AGT protein results in decreased expression of TIMP1 protein]; Folic Acid inhibits the reaction [AGT protein results in decreased expression of TIMP2 protein]; Folic Acid inhibits the reaction [AGT protein results in decreased expression of TIMP3 protein]; Folic Acid inhibits the reaction [AGT protein results in decreased expression of TIMP4 protein]; Folic Acid inhibits the reaction [AGT protein results in decreased expression of VEGFA protein]; Folic Acid inhibits the reaction [AGT protein results in increased expression of and results in increased activity of MMP2 protein]; Folic Acid inhibits the reaction [AGT protein results in increased expression of and results in increased activity of MMP9 protein]; Folic Acid inhibits the reaction [AGT protein results in increased expression of COL18A1 protein]; Folic Acid inhibits the reaction [AGT protein results in increased expression of CYBB protein]; Folic Acid inhibits the reaction [AGT protein results in increased expression of DDAH1 mRNA]; Folic Acid inhibits the reaction [AGT protein results in increased expression of DDAH1 protein]; Folic Acid inhibits the reaction [AGT protein results in increased expression of NOX4 protein]; Folic Acid inhibits the reaction [AGT protein results in increased expression of PLG protein]
Folic Acid results in decreased expression of AGT mRNA

PMID:15728788 PMID:22083158 PMID:24386282 PMID:25629700

NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944

G

ATP/GTP binding carboxypeptidase 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of AGTPBP1 gene

NCBI chr17:5,092,108...5,244,414
Ensembl chr17:5,126,146...5,244,420

G

angiotensin II receptor, type 1a

multiple interactions
decreases expression

EXP
ISO

candesartan inhibits the reaction [Folic Acid results in increased localization of [AGT protein binds to AGTR1A protein]]; Folic Acid results in increased localization of [AGT protein binds to AGTR1A protein]; Losartan inhibits the reaction [Folic Acid results in increased localization of [AGT protein binds to AGTR1A protein]]
Folic Acid results in decreased expression of AGTR1A mRNA
Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of AGTR1A mRNA]

PMID:15728788 PMID:22206623 PMID:25629700

NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,381,467...34,435,660

G

angiotensin II receptor, type 2

increases expression

ISO

Folic Acid results in increased expression of AGTR2 mRNA; Folic Acid results in increased expression of AGTR2 protein

NCBI chr X:116,914,320...116,918,504
Ensembl chr X:116,913,656...116,918,745

G

alanine--glyoxylate aminotransferase

decreases expression

ISO

Folic Acid results in decreased expression of AGXT mRNA

NCBI chr 9:101,122,793...101,132,746
Ensembl chr 9:101,122,793...101,132,745

G

adenosylhomocysteinase

multiple interactions
decreases expression
increases expression

ISO
EXP

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AHCY mRNA; [Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in decreased expression of AHCY mRNA; [Choline deficiency co-treated with Folic Acid deficiency] affects the expression of AHCY mRNA; [Choline deficiency co-treated with Folic Acid deficiency] inhibits the reaction [CEBPB protein binds to AHCY promoter]; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of AHCY mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of AHCY gene
Folic Acid deficiency results in decreased expression of AHCY mRNA; Folic Acid deficiency results in decreased expression of AHCY protein
[Folic Acid deficiency co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of AHCY protein
Folic Acid results in increased expression of AHCY mRNA; Folic Acid results in increased expression of AHCY protein

PMID:19566968 PMID:20938992 PMID:22206623 PMID:23439872 PMID:25384423 More...

NCBI chr 3:164,029,338...164,044,562
Ensembl chr 3:164,029,338...164,044,587

G

adenosylhomocysteinase-like 1

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AHCYL1 mRNA
Folic Acid results in decreased expression of AHCYL1 mRNA

PMID:22206623 PMID:25629700

NCBI chr 2:197,982,335...198,016,770
Ensembl chr 2:197,982,344...198,033,930

G

AHNAK nucleoprotein

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AHNAK mRNA; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of AHNAK mRNA]
Folic Acid results in increased expression of AHNAK mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr 1:215,311,289...215,400,010
Ensembl chr 1:215,321,931...215,400,675

G

aryl hydrocarbon receptor

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AHR mRNA

NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901

G

aryl-hydrocarbon receptor repressor

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of AHRR gene

NCBI chr 1:30,822,219...30,917,251
Ensembl chr 1:30,810,866...30,952,866

G

activator of Hsp90 ATPase activity 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AHSA1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of AHSA1 gene

PMID:20938992 PMID:22206623

NCBI chr 6:112,644,287...112,652,290
Ensembl chr 6:112,644,479...112,655,595

G

activator of HSP90 ATPase homolog 2

multiple interactions

ISO

[Ethanol co-treated with Folic Acid] results in increased expression of AHSA2 mRNA

NCBI chr14:101,677,447...101,688,706
Ensembl chr14:101,677,447...101,686,923

G

alpha-2-HS-glycoprotein

decreases expression

ISO

Folic Acid results in decreased expression of AHSG mRNA

NCBI chr11:91,625,975...91,632,583
Ensembl chr11:91,625,975...91,634,039

G

axin interactor, dorsalization associated

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of AIDA mRNA]

NCBI chr13:97,471,931...97,499,531
Ensembl chr13:97,471,604...97,499,535

G

allograft inflammatory factor 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of AIF1 mRNA

NCBI chr20:3,651,435...3,657,341
Ensembl chr20:3,652,243...3,657,339

G

androgen-induced 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AIG1 mRNA

NCBI chr 1:9,866,546...10,089,454
Ensembl chr 1:9,866,548...10,089,155

G

aminoacyl tRNA synthetase complex-interacting multifunctional protein 1

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of AIMP1 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AIMP1 mRNA

PMID:22206623 PMID:25629700

NCBI chr 2:223,825,930...223,849,477
Ensembl chr 2:223,825,931...223,849,994

G

ajuba LIM protein

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AJUBA mRNA

NCBI chr15:31,989,796...32,000,042
Ensembl chr15:31,989,799...32,000,042

G

adenylate kinase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of AK1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AK1 mRNA

PMID:20938992 PMID:22206623

NCBI chr 3:36,310,113...36,320,760
Ensembl chr 3:36,310,197...36,320,757

G

adenylate kinase 2

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of AK2 gene
Folic Acid results in decreased expression of AK2 mRNA

PMID:20938992 PMID:25629700

NCBI chr 5:146,609,469...146,649,008
Ensembl chr 5:146,630,445...146,650,610

G

adenylate kinase 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AK3 mRNA

NCBI chr 1:236,151,012...236,178,689
Ensembl chr 1:236,151,012...236,178,183

G

adenylate kinase 4

affects expression
decreases expression
multiple interactions

ISO

Folic Acid affects the expression of AK4 mRNA
Folic Acid results in decreased expression of AK4 mRNA
[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of AK4 mRNA

PMID:17320366 PMID:20938992 PMID:25629700

NCBI chr 5:121,154,565...121,214,403
Ensembl chr 5:121,154,572...121,214,401

G

adenylate kinase 6

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AK6 mRNA

NCBI chr 2:33,528,388...33,540,445
Ensembl chr 2:33,528,035...33,540,441
Ensembl chr20:33,528,035...33,540,441

G

adenylate kinase 7

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AK7 mRNA

NCBI chr 6:130,376,499...130,444,674
Ensembl chr 6:130,376,550...130,444,677

G

A-kinase anchoring protein 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of AKAP1 mRNA

NCBI chr10:74,118,232...74,151,366
Ensembl chr10:74,119,124...74,138,190

G

A-kinase anchoring protein 10

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of AKAP10 mRNA
Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of AKAP10 mRNA]

PMID:22206623 PMID:25629700

NCBI chr10:47,044,819...47,108,153
Ensembl chr10:47,044,819...47,108,203

G

A-kinase anchoring protein 12

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of AKAP12 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AKAP12 mRNA

PMID:11723236 PMID:21867686 PMID:22206623

NCBI chr 1:43,135,515...43,225,245
Ensembl chr 1:43,199,008...43,225,557

G

A-kinase anchoring protein 13

decreases expression

ISO

Folic Acid results in decreased expression of AKAP13 mRNA

NCBI chr 1:138,722,445...139,029,401
Ensembl chr 1:138,724,150...139,029,401

G

A-kinase anchoring protein 14

affects expression

ISO

Folic Acid affects the expression of AKAP14 mRNA

NCBI chr X:121,261,195...121,276,376
Ensembl chr X:121,259,899...121,276,376

G

A-kinase anchoring protein 17A

decreases expression

ISO

Folic Acid results in decreased expression of AKAP17B mRNA

NCBI chr12:21,424,202...21,428,308
Ensembl chr12:21,424,202...21,428,247

G

A-kinase anchoring protein 4

increases expression

ISO

Folic Acid results in increased expression of AKAP4 mRNA

NCBI chr X:18,107,256...18,117,549
Ensembl chr X:18,107,275...18,117,549

G

A-kinase anchoring protein 5

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of AKAP5 gene
Folic Acid results in decreased expression of AKAP5 mRNA

PMID:20938992 PMID:25629700

NCBI chr 6:100,787,169...100,796,712
Ensembl chr 6:100,790,148...100,796,620

G

A-kinase anchoring protein 6

decreases expression

ISO

Folic Acid results in decreased expression of AKAP6 mRNA

NCBI chr 6:75,919,350...76,359,667
Ensembl chr 6:75,919,513...76,355,036

G

A-kinase anchoring protein 7

decreases expression

ISO

Folic Acid results in decreased expression of AKAP7 mRNA

NCBI chr 1:21,906,503...22,168,663
Ensembl chr 1:21,906,676...22,037,090

G

A-kinase interacting protein 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AKIP1 mRNA

NCBI chr 1:173,169,520...173,178,445
Ensembl chr 1:173,169,458...173,178,445

G

akirin 1

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of AKIRIN1 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AKIRIN1 mRNA

PMID:22206623 PMID:25629700

NCBI chr 5:141,274,174...141,289,617
Ensembl chr 5:141,274,175...141,289,575

G

AT-hook transcription factor

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of AKNA gene

NCBI chr 5:81,792,928...81,839,936
Ensembl chr 5:81,792,929...81,831,528

G

AKNA domain containing 1

increases expression

ISO

Folic Acid results in increased expression of AKNAD1 mRNA

NCBI chr 2:199,076,864...199,120,402
Ensembl chr 2:199,081,596...199,120,375

G

aldo-keto reductase family 1 member A1

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of AKR1A1 mRNA]

NCBI chr 5:135,329,605...135,367,037
Ensembl chr 5:135,329,606...135,367,035

G

aldo-keto reductase family 1 member B1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AKR1B1 mRNA; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of AKR1B1 mRNA]

PMID:20938992 PMID:22206623

NCBI chr 4:63,899,222...63,913,315
Ensembl chr 4:63,899,222...63,913,315

G

aldo-keto reductase family 1, member B7

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of AKR1B7 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AKR1B7 mRNA

PMID:20938992 PMID:33549593

NCBI chr 4:64,043,901...64,083,751
Ensembl chr 4:64,020,686...64,064,909

G

aldo-keto reductase family 1, member C2

increases expression

ISO

Folic Acid results in increased expression of AKR1C21 mRNA

NCBI chr17:70,669,684...70,717,935
Ensembl chr17:70,669,710...70,685,686

G

aldo-keto reductase family 1, member C3

multiple interactions

ISO

[Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of AKR1C18 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AKR1C18 mRNA

PMID:20938992 PMID:29127188

NCBI chr17:71,020,884...71,037,779
Ensembl chr17:70,970,900...71,048,438

G

aldo-keto reductase family 7, member A2

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of AKR7A5 mRNA]

NCBI chr 5:156,835,589...156,844,127
Ensembl chr 5:156,835,551...156,844,109

G

AKT serine/threonine kinase 1

multiple interactions
increases phosphorylation

EXP
ISO

[Melatonin co-treated with Folic Acid] inhibits the reaction [Carbon Tetrachloride results in increased expression of AKT1 mRNA]; Folic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of AKT1 mRNA]
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of AKT1 mRNA; EGFR protein affects the reaction [Folic Acid results in increased phosphorylation of AKT1 protein]; Gefitinib inhibits the reaction [Folic Acid results in increased phosphorylation of AKT1 protein]
Folic Acid inhibits the reaction [aluminum maltolate results in decreased phosphorylation of AKT1 protein]; Folic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]; Folic Acid inhibits the reaction [Oxygen deficiency results in increased phosphorylation of AKT1 protein]; MIR19A mRNA affects the reaction [Folic Acid inhibits the reaction [aluminum maltolate results in decreased phosphorylation of AKT1 protein]]; MIR19B1 mRNA affects the reaction [Folic Acid inhibits the reaction [aluminum maltolate results in decreased phosphorylation of AKT1 protein]]

PMID:22206623 PMID:23255615 PMID:23374533 PMID:26974319 PMID:27113042 More...

NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610

G

AKT serine/threonine kinase 3

affects methylation
multiple interactions

EXP

Folic Acid affects the methylation of AKT3 gene
pyrimidin-2-one beta-ribofuranoside affects the reaction [Folic Acid affects the methylation of AKT3 gene]

NCBI chr13:91,475,839...91,758,060
Ensembl chr13:91,475,839...91,748,020

G

AKT interacting protein

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of AKTIP gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of AKTIP mRNA]

PMID:20938992 PMID:22206623

NCBI chr19:32,039,507...32,059,634
Ensembl chr19:32,039,466...32,067,178

G

aminolevulinate dehydratase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ALAD mRNA

NCBI chr 5:80,977,562...80,987,901
Ensembl chr 5:80,977,562...80,988,041

G

5'-aminolevulinate synthase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ALAS1 mRNA

NCBI chr 8:115,755,238...115,768,642
Ensembl chr 8:115,755,238...115,768,642

G

albumin

affects binding
decreases expression
multiple interactions
increases secretion
affects expression

ISO
EXP

ALB protein binds to Folic Acid
Folic Acid results in decreased expression of ALB protein
Folic Acid inhibits the reaction [Homocysteine inhibits the reaction [ALB protein binds to Bilirubin]]; Folic Acid inhibits the reaction [phenylhydrazine inhibits the reaction [ALB protein binds to Bilirubin]]
Folic Acid deficiency results in increased secretion of ALB protein
CYBB mutant form inhibits the reaction [Folic Acid deficiency results in increased secretion of ALB protein]; Decitabine inhibits the reaction [Folic Acid results in decreased expression of ALB protein]; Nicorandil inhibits the reaction [Folic Acid results in decreased expression of ALB protein]; trichostatin A inhibits the reaction [Folic Acid results in decreased expression of ALB protein]; Trimetazidine inhibits the reaction [Folic Acid results in decreased expression of ALB protein]
Folic Acid affects the expression of ALB protein

PMID:16251605 PMID:17029005 PMID:21647593 PMID:33404076 PMID:33788065 More...

NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865

G

activated leukocyte cell adhesion molecule

decreases expression

ISO

Folic Acid results in decreased expression of ALCAM mRNA

NCBI chr11:61,804,932...62,005,250
Ensembl chr11:61,805,049...62,006,876

G

aldehyde dehydrogenase 18 family, member A1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ALDH18A1 mRNA
Folic Acid results in decreased expression of ALDH18A1 mRNA

PMID:20938992 PMID:25629700

NCBI chr 1:249,325,082...249,357,383
Ensembl chr 1:249,325,082...249,357,383

G

aldehyde dehydrogenase 1 family, member A1

affects expression
multiple interactions

ISO

Folic Acid affects the expression of ALDH1A1 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ALDH1A1 mRNA

PMID:17868486 PMID:22206623

NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500

G

aldehyde dehydrogenase 1 family, member A3

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ALDH1A3 mRNA; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ALDH1A3 mRNA]

PMID:20938992 PMID:22206623

NCBI chr 1:129,392,516...129,436,552
Ensembl chr 1:129,392,516...129,427,777

G

aldehyde dehydrogenase 1 family, member B1

multiple interactions
increases expression

ISO
EXP

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ALDH1B1 mRNA]
Folic Acid deficiency results in increased expression of ALDH1B1 protein
[Folic Acid deficiency co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of ALDH1B1 protein; [Methionine deficiency co-treated with Choline deficiency] inhibits the reaction [Folic Acid deficiency results in increased expression of ALDH1B1 protein]

PMID:19566968 PMID:22206623

NCBI chr 5:64,859,000...64,864,008
Ensembl chr 5:64,858,934...64,864,365

G

aldehyde dehydrogenase 1 family, member L1

increases degradation
affects activity
multiple interactions

ISO
EXP

ALDH1L1 protein results in increased degradation of Folic Acid
Folic Acid affects the activity of ALDH1L1 protein
Folic Acid affects the reaction [Ethanol results in decreased activity of ALDH1L1 protein]

PMID:16385189 PMID:16627483

NCBI chr 4:124,617,182...124,663,674
Ensembl chr 4:124,617,217...124,664,704

G

aldehyde dehydrogenase 1 family, member L2

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ALDH1L2 mRNA
Folic Acid results in decreased expression of ALDH1L2 mRNA

PMID:20938992 PMID:25629700

NCBI chr 7:22,141,872...22,193,403
Ensembl chr 7:22,141,842...22,193,398

G

aldehyde dehydrogenase 2 family member

multiple interactions
increases expression
decreases expression

ISO
EXP

[Betaine co-treated with Choline co-treated with Folic Acid co-treated with Methionine co-treated with Vitamin B 12 co-treated with Zinc Sulfate co-treated with Ethanol] results in increased expression of ALDH2 protein; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ALDH2 mRNA; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ALDH2 mRNA]
Folic Acid deficiency results in increased expression of ALDH2 protein
[Folic Acid deficiency co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of ALDH2 protein
Folic Acid results in decreased expression of ALDH2 mRNA

PMID:19566968 PMID:20118189 PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr12:40,610,244...40,643,220
Ensembl chr12:40,610,224...40,643,219

G

aldehyde dehydrogenase 3 family, member A1

decreases expression

ISO

Folic Acid results in decreased expression of ALDH3A1 mRNA

NCBI chr10:46,392,464...46,402,151
Ensembl chr10:46,392,411...46,402,151

G

aldehyde dehydrogenase 3 family, member A2

decreases expression

ISO

Folic Acid results in decreased expression of ALDH3A2 mRNA

NCBI chr10:46,427,789...46,448,449
Ensembl chr10:46,407,993...46,448,648

G

aldehyde dehydrogenase 3 family, member B1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ALDH3B1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ALDH3B1 mRNA

PMID:20938992 PMID:22206623

NCBI chr 1:210,574,545...210,605,188
Ensembl chr 1:210,573,661...210,610,538

G

aldehyde dehydrogenase 3 family, member B3

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ALDH3B2 mRNA

NCBI chr 1:210,617,090...210,629,886
Ensembl chr 1:210,622,639...210,629,879

G

aldehyde dehydrogenase 4 family, member A1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ALDH4A1 mRNA; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of ALDH4A1 mRNA]

PMID:20938992 PMID:22206623

NCBI chr 5:157,163,189...157,188,673
Ensembl chr 5:157,162,945...157,188,673

G

aldehyde dehydrogenase 5 family, member A1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ALDH5A1 mRNA

NCBI chr17:40,560,373...40,586,711
Ensembl chr17:40,558,347...40,586,714

G

aldehyde dehydrogenase 6 family, member A1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ALDH6A1 mRNA

NCBI chr 6:109,809,092...109,829,725
Ensembl chr 6:109,809,122...109,829,743

G

aldehyde dehydrogenase 7 family, member A1

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ALDH7A1 gene
Folic Acid results in increased expression of ALDH7A1 mRNA

PMID:20938992 PMID:25629700

NCBI chr18:52,208,035...52,240,293
Ensembl chr18:52,204,161...52,240,467

G

aldehyde dehydrogenase 8 family, member A1

decreases expression

ISO

Folic Acid results in decreased expression of ALDH8A1 mRNA

NCBI chr 1:18,003,507...18,022,952
Ensembl chr 1:18,003,514...18,023,883

G

aldehyde dehydrogenase 9 family, member A1

multiple interactions
increases expression

ISO
EXP

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ALDH9A1 gene
[Methionine deficiency co-treated with Choline deficiency] inhibits the reaction [Folic Acid deficiency results in increased expression of ALDH9A1 protein]

PMID:19566968 PMID:20938992

NCBI chr13:82,038,679...82,055,478
Ensembl chr13:82,038,533...82,055,481

G

aldolase 1 A retrogene 2

increases expression

ISO

Folic Acid results in increased expression of ALDOART2 mRNA

NCBI chr 6:78,674,945...78,676,635
Ensembl chr 6:78,673,353...78,680,406

G

ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ALG1 mRNA

NCBI chr10:10,853,014...10,863,250
Ensembl chr10:10,853,014...10,863,239

G

ALG10, alpha-1,2-glucosyltransferase

decreases expression

ISO

Folic Acid results in decreased expression of ALG10B mRNA

NCBI chr 7:123,214,636...123,225,104
Ensembl chr 7:123,214,636...123,225,104

G

ALG14, UDP-N-acetylglucosaminyltransferase subunit

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ALG14 mRNA

NCBI chr 2:212,053,008...212,130,136
Ensembl chr 2:212,044,969...212,130,140

G

ALG2, alpha-1,3/1,6-mannosyltransferase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ALG2 mRNA

NCBI chr 5:66,564,328...66,568,887
Ensembl chr 5:66,564,330...66,568,887

G

ALG5, dolichyl-phosphate beta-glucosyltransferase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ALG5 mRNA

NCBI chr 2:141,087,126...141,101,397
Ensembl chr 2:141,087,147...141,102,951

G

ALG9, alpha-1,2-mannosyltransferase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ALG9 mRNA

NCBI chr 8:60,013,429...60,085,159
Ensembl chr 8:60,009,618...60,085,054

G

ALK receptor tyrosine kinase

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ALK gene

NCBI chr 6:28,631,431...29,351,321
Ensembl chr 6:28,632,197...29,349,721

G

alkB homolog 5, RNA demethylase

decreases expression

ISO

Folic Acid results in decreased expression of ALKBH5 mRNA

NCBI chr10:45,844,411...45,865,853
Ensembl chr10:45,843,656...45,869,658

G

alkB homolog 8, tRNA methyltransferase

decreases expression

ISO

Folic Acid results in decreased expression of ALKBH8 mRNA

NCBI chr 6:6,121,402...6,198,226
Ensembl chr 6:6,124,253...6,198,080

G

arachidonate 12-lipoxygenase, 12R type

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ALOX12B mRNA

NCBI chr10:54,361,898...54,373,776
Ensembl chr10:54,361,898...54,373,776

G

arachidonate 5-lipoxygenase

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ALOX5 mRNA

NCBI chr 4:151,203,948...151,251,126
Ensembl chr 4:151,203,949...151,251,126

G

arachidonate 5-lipoxygenase activating protein

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ALOX5AP mRNA; [Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of ALOX5AP mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ALOX5AP mRNA
Folic Acid results in decreased expression of ALOX5AP mRNA

PMID:20938992 PMID:22206623 PMID:25629700 PMID:29127188

NCBI chr12:10,785,254...10,809,295
Ensembl chr12:10,785,257...10,817,038

G

alkaline phosphatase, biomineralization associated

multiple interactions

ISO

[Ethanol co-treated with Folic Acid] results in decreased expression of ALPL mRNA

NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167

G

ALX homeobox 3

multiple interactions
affects response to substance
increases expression
decreases expression

ISO
EXP

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ALX3 gene
ALX3 protein affects the susceptibility to Folic Acid
Folic Acid results in increased expression of ALX3 mRNA
Dactinomycin inhibits the reaction [Folic Acid results in increased expression of ALX3 mRNA]
Folic Acid deficiency results in decreased expression of ALX3 mRNA

PMID:20534379 PMID:20938992

NCBI chr 2:197,919,381...197,929,795
Ensembl chr 2:197,919,381...197,929,795

G

ALX homeobox 4

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of ALX4 mRNA]

NCBI chr 3:100,067,052...100,103,624
Ensembl chr 3:100,067,052...100,103,624

G

Aly/REF export factor

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ALYREF mRNA

NCBI chr10:106,369,750...106,373,395
Ensembl chr10:106,369,750...106,373,395

G

alpha-methylacyl-CoA racemase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AMACR mRNA

NCBI chr 2:61,673,291...61,685,381
Ensembl chr 2:61,670,475...61,685,379

G

adenosylmethionine decarboxylase 1

increases activity
multiple interactions

ISO

Folic Acid results in increased activity of AMD1 protein
Reserpine inhibits the reaction [Folic Acid results in increased activity of AMD1 protein]

NCBI chr20:45,250,289...45,324,939
Ensembl chr20:45,250,289...45,265,982

G

amidohydrolase domain containing 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AMDHD2 mRNA

NCBI chr10:13,692,136...13,700,632
Ensembl chr10:13,692,146...13,700,632

G

APC membrane recruitment protein 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of AMER1 mRNA

NCBI chr X:64,310,492...64,326,377
Ensembl chr X:64,300,953...64,326,332

G

adhesion molecule with Ig like domain 3

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of AMIGO3 mRNA]

NCBI chr 8:117,620,499...117,622,025
Ensembl chr 8:117,616,629...117,626,577

G

AMMECR1 like

increases expression
multiple interactions

ISO

Folic Acid results in increased expression of AMMECR1L mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AMMECR1L mRNA

PMID:22206623 PMID:25629700

NCBI chr18:23,661,649...23,685,391
Ensembl chr18:23,661,341...23,685,649

G

amnion associated transmembrane protein

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of AMN gene
Folic Acid results in decreased expression of AMN mRNA

PMID:20938992 PMID:21867686

NCBI chr 6:136,132,567...136,140,008
Ensembl chr 6:136,132,567...136,140,008

G

antagonist of mitotic exit network 1 homolog

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of AMN1 mRNA]

NCBI chr 4:183,886,469...183,913,411
Ensembl chr 4:183,886,474...183,913,411

G

angiomotin

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of AMOT mRNA

NCBI chr X:113,778,990...113,837,846
Ensembl chr X:113,781,526...113,837,482

G

angiomotin-like 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of AMOTL1 gene

NCBI chr 8:19,630,139...19,749,027
Ensembl chr 8:19,634,510...19,748,869

G

adenosine monophosphate deaminase 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AMPD2 mRNA

NCBI chr 2:198,395,767...198,408,514
Ensembl chr 2:198,395,768...198,408,796

G

amphiphysin

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of AMPH mRNA
Folic Acid results in decreased expression of AMPH mRNA

PMID:22206623 PMID:25629700

NCBI chr17:50,435,018...50,678,583
Ensembl chr17:50,435,018...50,678,501

G

archaelysin family metallopeptidase 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AMZ2 mRNA

NCBI chr10:94,901,053...94,911,629
Ensembl chr10:94,901,129...94,911,627

G

anaphase promoting complex subunit 1

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of ANAPC1 mRNA]

NCBI chr 3:136,303,350...136,383,464
Ensembl chr 3:136,303,413...136,383,464

G

anaphase promoting complex subunit 11

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ANAPC11 mRNA

NCBI chr10:106,373,610...106,384,633
Ensembl chr10:106,373,634...106,384,633

G

anaphase promoting complex subunit 13

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ANAPC13 mRNA

NCBI chr 8:112,084,405...112,092,821
Ensembl chr 8:112,084,405...112,092,821

G

anaphase promoting complex subunit 16

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ANAPC16 mRNA

NCBI chr20:28,470,282...28,484,601
Ensembl chr20:28,470,282...28,484,987

G

anaphase promoting complex subunit 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ANAPC2 mRNA

NCBI chr 3:28,484,590...28,496,338
Ensembl chr 3:28,484,614...28,496,337

G

anaphase promoting complex subunit 4

decreases expression

ISO

Folic Acid results in decreased expression of ANAPC4 mRNA

NCBI chr14:62,338,798...62,370,572
Ensembl chr14:62,338,798...62,370,572

G

anaphase-promoting complex subunit 5

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ANAPC5 gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ANAPC5 mRNA]
Folic Acid results in decreased expression of ANAPC5 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr12:39,409,519...39,442,518
Ensembl chr12:39,385,399...39,442,762

G

anaphase promoting complex subunit 7

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of ANAPC7 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ANAPC7 mRNA

PMID:22206623 PMID:25629700

NCBI chr12:39,793,518...39,821,614
Ensembl chr12:39,794,349...39,821,066

G

angiogenin, ribonuclease A family, member 2

decreases expression

ISO

Folic Acid results in decreased expression of ANG2 mRNA

NCBI chr15:26,871,842...26,889,421
Ensembl chr15:26,871,838...26,889,421

G

angiopoietin-like 1

increases expression

ISO

Folic Acid results in increased expression of ANGPTL1 mRNA

NCBI chr13:71,463,913...71,531,810
Ensembl chr13:71,511,727...71,531,818

G

angiopoietin-like 2

increases expression

ISO

Folic Acid results in increased expression of ANGPTL2 mRNA

NCBI chr 3:36,914,876...36,944,715
Ensembl chr 3:36,914,745...36,945,876

G

angiopoietin-like 6

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ANGPTL6 gene

NCBI chr 8:27,689,804...27,696,172
Ensembl chr 8:27,689,806...27,696,111

G

angiopoietin like 7

increases expression

ISO

Folic Acid results in increased expression of ANGPTL7 mRNA

NCBI chr 5:164,215,223...164,220,408
Ensembl chr 5:164,215,223...164,220,584

G

ankyrin 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ANK2 mRNA

NCBI chr 2:218,052,555...218,628,414
Ensembl chr 2:218,052,555...218,537,259

G

ankyrin 3

decreases expression

ISO

Folic Acid results in decreased expression of ANK3 mRNA

NCBI chr20:18,601,307...19,224,790
Ensembl chr20:18,601,826...19,084,879

G

ANKH inorganic pyrophosphate transport regulator

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ANK mRNA

NCBI chr 2:79,883,350...80,011,222
Ensembl chr 2:79,883,544...80,011,699

G

ankyrin repeat and KH domain containing 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ANKHD1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ANKHD1 gene

PMID:20938992 PMID:22206623

NCBI chr18:28,436,296...28,534,954
Ensembl chr18:28,436,394...28,534,954

G

ankyrin repeat and IBR domain containing 1

decreases expression

ISO

Folic Acid results in decreased expression of ANKIB1 mRNA

NCBI chr 4:31,288,393...31,412,500
Ensembl chr 4:31,288,142...31,412,504

G

ankyrin repeat and LEM domain containing 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ANKLE1 mRNA

NCBI chr16:18,109,865...18,116,999
Ensembl chr16:18,110,476...18,114,244

G

ankyrin repeat family A member 2

multiple interactions

ISO

[Folic Acid deficiency co-treated with Methotrexate] results in increased expression of ANKRA2 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ANKRA2 mRNA

PMID:22206623 PMID:24657277

NCBI chr 2:31,347,158...31,358,002
Ensembl chr 2:31,347,090...31,364,394

G

ankyrin repeat domain 1

increases expression
multiple interactions

ISO

Folic Acid results in increased expression of ANKRD1 mRNA
[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ANKRD1 mRNA

PMID:17868486 PMID:20938992

NCBI chr 1:243,228,460...243,237,014
Ensembl chr 1:243,228,448...243,263,751

G

ankyrin repeat domain 10

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ANKRD10 mRNA

NCBI chr16:84,566,021...84,591,849
Ensembl chr16:84,568,506...84,591,846

G

ankyrin repeat domain 12

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ANKRD12 gene
Folic Acid results in decreased expression of ANKRD12 mRNA

PMID:20938992 PMID:25629700

NCBI chr 9:113,030,127...113,134,816
Ensembl chr 9:113,030,919...113,134,762

G

ankyrin repeat domain 13B

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ANKRD13B mRNA; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ANKRD13B mRNA]

PMID:20938992 PMID:22206623

NCBI chr10:62,817,791...62,836,456
Ensembl chr10:62,817,778...62,836,635

G

ankyrin repeat domain 13D

increases expression

ISO

Folic Acid results in increased expression of ANKRD13D mRNA

NCBI chr 1:210,995,012...211,007,430
Ensembl chr 1:210,995,148...211,007,369

G

ankyrin repeat domain 16

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ANKRD16 gene

NCBI chr17:71,645,171...71,658,377
Ensembl chr17:71,647,107...71,658,377

G

ankyrin repeat domain 24

increases expression
multiple interactions

ISO

Folic Acid results in increased expression of ANKRD24 mRNA
Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of ANKRD24 mRNA]

PMID:22206623 PMID:25629700

NCBI chr 7:8,712,720...8,731,910
Ensembl chr 7:8,712,722...8,731,910

G

ankyrin repeat domain containing 26

decreases expression

ISO

Folic Acid results in decreased expression of ANKRD26 mRNA

NCBI chr 4:153,342,901...153,412,321
Ensembl chr 4:153,343,578...153,412,256

G

ankyrin repeat domain 27

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ANKRD27 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ANKRD27 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ANKRD27 gene

PMID:20938992 PMID:22206623

NCBI chr 1:97,387,997...97,440,501
Ensembl chr 1:97,388,099...97,440,501

G

ankyrin repeat domain 28

decreases expression

ISO

Folic Acid results in decreased expression of ANKRD28 mRNA

NCBI chr16:6,924,868...7,056,593
Ensembl chr16:6,924,882...7,056,593

G

ankyrin repeat domain 34A

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ANKRD34A gene

NCBI chr 2:186,818,496...186,823,921
Ensembl chr 2:186,817,216...186,824,467

G

ankyrin repeat domain 34B

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ANKRD34B gene

NCBI chr 2:25,386,452...25,402,376
Ensembl chr 2:25,386,158...25,403,265

G

ankyrin repeat domain 39

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ANKRD39 mRNA

NCBI chr 9:46,277,659...46,286,050
Ensembl chr 9:46,279,952...46,286,043

G

ankyrin repeat domain 40

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of ANKRD40 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ANKRD40 mRNA

PMID:22206623 PMID:25629700

NCBI chr10:79,778,966...79,792,212
Ensembl chr10:56,415,260...56,416,345
Ensembl chr10:56,415,260...56,416,345

G

ankyrin repeat domain 44

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of ANKRD44 mRNA]

NCBI chr 9:63,621,193...63,921,999
Ensembl chr 9:63,555,869...63,921,940

G

ankyrin repeat domain 45

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of ANKRD45 mRNA]

NCBI chr13:75,957,047...75,984,868
Ensembl chr13:75,957,926...75,984,910

G

ankyrin repeat domain 46

decreases expression

ISO

Folic Acid results in decreased expression of ANKRD46 mRNA

NCBI chr 7:69,532,303...69,553,311
Ensembl chr 7:69,532,304...69,545,421

G

ankyrin repeat domain 49

decreases expression

ISO

Folic Acid results in decreased expression of ANKRD49 mRNA

NCBI chr 8:19,908,968...19,913,656
Ensembl chr 8:19,908,973...19,913,656

G

ankyrin repeat domain containing 50

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of ANKRD50 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ANKRD50 mRNA

PMID:22206623 PMID:25629700

NCBI chr 2:123,394,311...123,428,788
Ensembl chr 2:123,396,606...123,427,340

G

ankyrin repeat domain 53

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ANKRD53 gene

NCBI chr 4:117,804,702...117,810,650
Ensembl chr 4:117,804,548...117,810,645

G

ankyrin repeat and sterile alpha motif domain containing 1A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ANKS1 mRNA

NCBI chr20:5,965,421...6,118,875
Ensembl chr20:5,965,028...6,118,875

G

ankyrin repeat and sterile alpha motif domain containing 3

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ANKS3 gene

NCBI chr10:11,121,504...11,142,261
Ensembl chr10:11,121,553...11,142,491

G

ankyrin repeat and sterile alpha motif domain containing 4B

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ANKS4B mRNA

NCBI chr 1:183,934,528...183,989,127
Ensembl chr 1:183,978,769...183,989,122

G

ankyrin repeat and sterile alpha motif domain containing 6

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ANKS6 mRNA

NCBI chr 5:66,104,770...66,146,186
Ensembl chr 5:66,104,773...66,146,186

G

anillin, actin binding protein

multiple interactions
decreases expression

ISO

[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of ANLN mRNA
Folic Acid results in decreased expression of ANLN mRNA

PMID:24657277 PMID:25629700

NCBI chr 8:29,134,222...29,197,513
Ensembl chr 8:29,134,222...29,197,513

G

anoctamin 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ANO1 gene; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ANO1 mRNA
Folic Acid results in decreased expression of ANO1 mRNA

PMID:20938992 PMID:21867686

NCBI chr 1:209,180,755...209,329,413
Ensembl chr 1:209,180,755...209,329,550

G

anoctamin 10

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ANO10 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ANO10 mRNA
Folic Acid results in decreased expression of ANO10 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr 8:130,719,177...130,838,243
Ensembl chr 8:130,718,755...130,877,636

G

anoctamin 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ANO2 mRNA

NCBI chr 4:160,200,471...160,541,830
Ensembl chr 4:160,182,152...160,541,821

G

anoctamin 6

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ANO6 mRNA

NCBI chr 7:128,812,842...128,992,805
Ensembl chr 7:128,813,068...128,992,799

G

anoctamin 7

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ANO7 gene

NCBI chr 9:101,364,915...101,392,711
Ensembl chr 9:101,364,842...101,394,173

G

anoctamin 8

increases expression

ISO

Folic Acid results in increased expression of ANO8 mRNA

NCBI chr16:18,197,829...18,207,205
Ensembl chr16:18,197,001...18,207,234

G

acidic nuclear phosphoprotein 32 family member A

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ANP32A mRNA
Folic Acid results in decreased expression of ANP32A mRNA

PMID:21867686 PMID:22206623 PMID:25629700

NCBI chr 8:71,724,578...71,760,922
Ensembl chr 8:71,724,531...71,760,922

G

acidic nuclear phosphoprotein 32 family member B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ANP32B mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ANP32B gene

PMID:20938992 PMID:22206623

NCBI chr 5:65,538,872...65,561,305
Ensembl chr 5:65,538,535...65,561,437

G

acidic nuclear phosphoprotein 32 family member E

decreases expression

ISO

Folic Acid results in decreased expression of ANP32E mRNA

NCBI chr 2:186,161,520...186,177,984
Ensembl chr 2:186,161,532...186,177,986

G

alanyl aminopeptidase, membrane

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ANPEP mRNA

NCBI chr 1:143,176,645...143,219,447
Ensembl chr 1:143,176,645...143,195,101

G

adenine nucleotide translocase lysine methyltransferase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ANTKMT mRNA

NCBI chr10:15,316,797...15,320,950
Ensembl chr10:15,316,772...15,318,656

G

ANTXR cell adhesion molecule 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ANTXR1 mRNA

NCBI chr 4:121,148,102...121,335,549
Ensembl chr 4:121,148,103...121,336,892

G

ANTXR cell adhesion molecule 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ANTXR2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ANTXR2 gene

PMID:20938992 PMID:22206623

NCBI chr14:11,845,774...11,986,166
Ensembl chr14:11,845,700...11,986,168

G

annexin A1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ANXA1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ANXA1 mRNA

PMID:20938992 PMID:22206623

NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:227,287,717...227,306,831

G

annexin A11

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ANXA11 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ANXA11 gene

PMID:20938992 PMID:22206623

NCBI chr16:1,419,627...1,464,590
Ensembl chr16:1,418,351...1,464,839

G

annexin A13

affects expression
multiple interactions

ISO

Folic Acid affects the expression of ANXA13 mRNA
[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ANXA13 mRNA

PMID:17868486 PMID:20938992

NCBI chr 7:91,773,844...91,826,386
Ensembl chr 7:91,770,861...91,826,386

G

annexin A2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ANXA2 mRNA

NCBI chr 8:78,986,252...79,022,638
Ensembl chr 8:78,986,242...79,022,631

G

annexin A3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ANXA3 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ANXA3 mRNA

PMID:20938992 PMID:22206623

NCBI chr14:13,031,675...13,085,678
Ensembl chr14:13,023,762...13,085,849

G

annexin A4

multiple interactions

EXP
ISO

[Folic Acid deficiency co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of ANXA4 protein
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ANXA4 mRNA

PMID:19566968 PMID:22206623

NCBI chr 4:120,741,750...120,798,534
Ensembl chr 4:120,741,750...120,798,513

G

annexin A5

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ANXA5 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ANXA5 mRNA

PMID:20938992 PMID:22206623

NCBI chr 2:121,242,133...121,272,935
Ensembl chr 2:121,242,136...121,281,400

G

annexin A7

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ANXA7 mRNA]

NCBI chr15:3,869,180...3,897,827
Ensembl chr15:3,870,974...3,898,891

G

annexin A8

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ANXA8 mRNA]

NCBI chr16:9,403,267...9,418,317
Ensembl chr16:9,403,353...9,418,310

G

acyloxyacyl hydrolase

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AOAH mRNA

NCBI chr17:48,503,812...48,745,161
Ensembl chr17:48,503,812...48,745,146

G

amine oxidase, copper containing 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AOC1 mRNA; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of AOC1 mRNA]

PMID:20938992 PMID:22206623

NCBI chr 4:79,143,126...79,162,705
Ensembl chr 4:79,143,126...79,162,704

G

amine oxidase, copper containing 2, pseudogene 1

decreases expression

ISO

Folic Acid results in decreased expression of AOC2 mRNA

NCBI chr10:86,767,268...86,768,734

G

aminopeptidase O

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of AOPEP mRNA]

NCBI chr17:1,817,001...2,133,008
Ensembl chr17:1,817,001...2,133,104

G

adaptor related protein complex 1 subunit beta 1

decreases expression

ISO

Folic Acid results in decreased expression of AP1B1 mRNA

NCBI chr14:84,093,529...84,144,835
Ensembl chr14:84,093,559...84,144,892

G

adaptor related protein complex 1 subunit gamma 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of AP1G1 gene
Folic Acid results in decreased expression of AP1G1 mRNA

PMID:20938992 PMID:25629700

NCBI chr19:54,654,101...54,740,586
Ensembl chr19:54,620,807...54,740,586

G

adaptor related protein complex 1 subunit mu 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AP1M2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of AP1M2 gene

NCBI chr 8:28,114,748...28,132,767
Ensembl chr 8:28,114,748...28,132,642

G

adaptor related protein complex 1 subunit sigma 1

decreases expression

ISO

Folic Acid results in decreased expression of AP1S1 mRNA

NCBI chr12:25,261,958...25,272,483
Ensembl chr12:25,262,036...25,272,483

G

adaptor related protein complex 1 subunit sigma 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AP1S2 mRNA

NCBI chr X:34,204,601...34,230,819
Ensembl chr X:34,204,603...34,228,529

G

adaptor related protein complex 1 subunit sigma 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AP1S3 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of AP1S3; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of AP1S3 gene; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AP1S3 mRNA

PMID:20938992 PMID:22206623

NCBI chr 9:88,399,109...88,458,396
Ensembl chr 9:88,399,109...88,488,089

G

adaptor related protein complex 2 subunit alpha 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of AP2A1 mRNA

NCBI chr 1:104,520,789...104,550,655
Ensembl chr 1:104,520,792...104,550,655

G

adaptor related protein complex 2 subunit alpha 2

multiple interactions
decreases expression

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of AP2A2 mRNA]
Folic Acid results in decreased expression of AP2A2 mRNA

PMID:22206623 PMID:25629700

NCBI chr 1:206,081,856...206,155,146
Ensembl chr 1:206,081,878...206,155,150

G

adaptor related protein complex 2 subunit beta 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AP2B1 mRNA

NCBI chr10:68,596,925...68,702,547
Ensembl chr10:68,597,093...68,702,539

G

adaptor related protein complex 2 subunit mu 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AP2M1 mRNA

NCBI chr11:93,859,690...93,868,600
Ensembl chr11:93,859,690...93,868,480

G

adaptor related protein complex 2 subunit sigma 1

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of AP2S1 mRNA]

NCBI chr 1:86,545,601...86,557,007
Ensembl chr 1:86,545,350...86,557,009

G

adaptor related protein complex 3 subunit beta 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AP3B1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of AP3B1 gene

PMID:20938992 PMID:22206623

NCBI chr 2:27,331,241...27,535,683
Ensembl chr 2:27,334,900...27,537,702

G

adaptor related protein complex 3 subunit beta 2

increases expression
multiple interactions

ISO

Folic Acid results in increased expression of AP3B2 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of AP3B2 mRNA

PMID:22206623 PMID:25629700

NCBI chr 1:144,821,819...144,854,533
Ensembl chr 1:144,821,819...144,854,432

G

adaptor related protein complex 3 subunit delta 1

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of AP3D1 mRNA]

NCBI chr 7:9,620,909...9,656,350
Ensembl chr 7:9,620,968...9,656,342

G

adaptor related protein complex 3 subunit mu 1

decreases expression

ISO

Folic Acid results in decreased expression of AP3M1 mRNA

NCBI chr15:3,285,591...3,314,139
Ensembl chr15:3,295,444...3,313,104

G

adaptor related protein complex 3 subunit mu 2

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of AP3M2; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of AP3M2 gene; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AP3M2 mRNA
Folic Acid results in decreased expression of AP3M2 mRNA

PMID:20938992 PMID:25629700

NCBI chr16:75,908,459...75,937,915
Ensembl chr16:75,920,084...75,937,923

G

adaptor related protein complex 3 subunit sigma 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AP3S1 mRNA

NCBI chr18:41,649,321...41,718,221
Ensembl chr18:41,648,796...41,767,641

G

adaptor related protein complex 4 subunit epsilon 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of AP4E1 gene

NCBI chr 3:134,726,338...134,792,820
Ensembl chr 3:134,726,287...134,792,818

G

adaptor related protein complex 4 subunit mu 1

decreases expression

ISO

Folic Acid results in decreased expression of AP4M1 mRNA

NCBI chr12:22,163,474...22,171,734
Ensembl chr12:22,163,466...22,171,731

G

adaptor related protein complex 5 subunit mu 1

decreases expression

ISO

Folic Acid results in decreased expression of AP5M1 mRNA

NCBI chr15:24,835,122...24,864,854
Ensembl chr15:24,835,100...24,862,606

G

adaptor related protein complex 5 subunit zeta 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AP5Z1 mRNA

NCBI chr12:17,207,315...17,222,975
Ensembl chr12:17,207,315...17,222,467

G

apoptotic peptidase activating factor 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of APAF1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of APAF1 gene

NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:27,381,855...27,466,772

G

amyloid beta precursor protein binding family A member 3

decreases expression

ISO

Folic Acid results in decreased expression of APBA3 mRNA

NCBI chr 7:9,096,936...9,103,457
Ensembl chr 7:9,095,975...9,101,909

G

amyloid beta precursor protein binding family B member 1 interacting protein

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of APBB1IP mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of APBB1IP mRNA

PMID:20938992 PMID:22206623

NCBI chr17:89,849,474...89,941,099
Ensembl chr17:89,671,716...89,941,089

G

APC regulator of WNT signaling pathway

decreases expression
increases methylation

ISO

Folic Acid results in decreased expression of APC mRNA
Folic Acid results in increased methylation of APC promoter

NCBI chr18:26,138,382...26,196,021
Ensembl chr18:26,102,679...26,197,022

G

APC regulator of WNT signaling pathway 2

increases expression
multiple interactions

ISO

Folic Acid results in increased expression of APC2 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of APC2 mRNA

PMID:22206623 PMID:25629700

NCBI chr 7:10,043,010...10,065,037
Ensembl chr 7:10,043,010...10,065,210

G

APC down-regulated 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of APCDD1 mRNA

NCBI chr18:58,655,696...58,686,359
Ensembl chr18:58,655,919...58,686,356

G

amyloid P component, serum

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of APCS mRNA

NCBI chr13:87,905,532...87,906,508
Ensembl chr13:87,905,532...87,928,824

G

acylaminoacyl-peptide hydrolase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of APEH mRNA

NCBI chr 8:117,652,390...117,661,502
Ensembl chr 8:117,652,393...117,661,711

G

apurinic/apyrimidinic endodeoxyribonuclease 1

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of APEX1 mRNA]

NCBI chr15:26,618,146...26,620,330
Ensembl chr15:26,618,224...26,620,329

G

aph-1 homolog A, gamma secretase subunit

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of APH1A mRNA

NCBI chr 2:186,123,023...186,130,886
Ensembl chr 2:186,127,323...186,132,045

G

aph-1 homolog B, gamma secretase subunit

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of APH1B; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of APH1B mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of APH1B gene

NCBI chr 8:76,310,380...76,334,146
Ensembl chr 8:76,310,380...76,331,428

G

apoptosis inhibitor 5

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of API5 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of API5 mRNA

PMID:22206623 PMID:25629700

NCBI chr 3:100,833,417...100,858,580
Ensembl chr 3:100,833,417...100,858,580

G

APAF1 interacting protein

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of APIP mRNA

NCBI chr 3:109,886,919...109,913,295
Ensembl chr 3:109,886,953...109,915,862

G

aprataxin and PNKP like factor

decreases expression

ISO

Folic Acid results in decreased expression of APLF mRNA

NCBI chr 4:121,627,800...121,679,980
Ensembl chr 4:121,627,800...121,679,961

G

apelin

decreases expression

ISO

Folic Acid results in decreased expression of APLN mRNA

NCBI chr X:132,058,739...132,091,518
Ensembl chr X:132,081,759...132,091,246

G

apelin receptor

decreases expression

ISO

Folic Acid results in decreased expression of APLNR mRNA

NCBI chr 3:90,624,055...90,627,700
Ensembl chr 3:90,624,012...90,627,908

G

amyloid beta precursor like protein 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of APLP1 mRNA

NCBI chr 1:94,824,330...94,834,705
Ensembl chr 1:94,824,072...94,834,610

G

apolipoprotein A1

multiple interactions

ISO
EXP

[APOE gene mutant form affects the susceptibility to Folic Acid] which results in increased expression of APOA1 protein
[Folic Acid deficiency co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of APOA1 protein

PMID:17118406 PMID:19566968

NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:55,423,825...55,425,729

G

apolipoprotein A2

multiple interactions

ISO

[APOE gene mutant form affects the susceptibility to Folic Acid] which results in increased expression of APOA2 protein

NCBI chr13:86,176,767...86,178,819
Ensembl chr13:86,174,741...86,179,410

G

apolipoprotein A4

multiple interactions

ISO

[APOE gene mutant form affects the susceptibility to Folic Acid] which results in increased expression of APOA4 mRNA; [APOE gene mutant form affects the susceptibility to Folic Acid] which results in increased expression of APOA4 protein; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of APOA4 mRNA

PMID:17118406 PMID:20938992

NCBI chr 8:55,435,779...55,438,160
Ensembl chr 8:55,434,168...55,438,164

G

apolipoprotein A5

decreases expression

ISO

Folic Acid results in decreased expression of APOA5 mRNA

NCBI chr 8:55,446,329...55,460,509
Ensembl chr 8:55,456,899...55,460,507

G

apolipoprotein B

multiple interactions
decreases expression
increases expression

ISO

[Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with Oleic Acid co-treated with Folic Acid co-treated with Vitamin B 6 co-treated with Vitamin E] results in decreased expression of APOB protein
Folic Acid deficiency results in decreased expression of APOB mRNA
[APOE gene mutant form affects the susceptibility to Folic Acid] which results in decreased expression of APOB protein
Folic Acid results in increased expression of APOB mRNA

PMID:17118406 PMID:17237316 PMID:17868486 PMID:30153273

NCBI chr 6:36,563,704...36,603,300
Ensembl chr 6:36,563,704...36,611,814

G

apolipoprotein B mRNA editing enzyme catalytic subunit 1

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of APOBEC1 mRNA]

NCBI chr 4:157,472,879...157,500,496
Ensembl chr 4:157,472,868...157,498,909

G

apolipoprotein B receptor

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of APOBR mRNA

NCBI chr 1:190,599,595...190,603,782
Ensembl chr 1:190,597,638...190,616,809

G

apolipoprotein C2

decreases expression

ISO

Folic Acid results in decreased expression of APOC2 mRNA

NCBI chr 1:88,457,397...88,462,365
Ensembl chr 1:88,457,396...88,463,438

G

apolipoprotein D

increases expression

ISO

Folic Acid results in increased expression of APOD mRNA

NCBI chr11:82,936,216...82,957,264
Ensembl chr11:82,936,038...82,957,263

G

apolipoprotein E

affects response to substance
decreases expression
multiple interactions

ISO

APOE gene mutant form affects the susceptibility to Folic Acid
Folic Acid results in decreased expression of APOE mRNA
[APOE gene mutant form affects the susceptibility to Folic Acid] which results in decreased abundance of 8-epi-prostaglandin F2alpha; [APOE gene mutant form affects the susceptibility to Folic Acid] which results in decreased expression of APOB protein; [APOE gene mutant form affects the susceptibility to Folic Acid] which results in increased abundance of Cholesterol, HDL analog; [APOE gene mutant form affects the susceptibility to Folic Acid] which results in increased abundance of Cholesterol, LDL; [APOE gene mutant form affects the susceptibility to Folic Acid] which results in increased abundance of Cholesterol, VLDL; [APOE gene mutant form affects the susceptibility to Folic Acid] which results in increased expression of APOA1 protein; [APOE gene mutant form affects the susceptibility to Folic Acid] which results in increased expression of APOA2 protein; [APOE gene mutant form affects the susceptibility to Folic Acid] which results in increased expression of APOA4 mRNA; [APOE gene mutant form affects the susceptibility to Folic Acid] which results in increased expression of APOA4 protein; Folic Acid affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of CCL2 mRNA]; Folic Acid affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of CCL2 protein]; Folic Acid affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of DNMT1 mRNA]; Folic Acid affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of DNMT3A mRNA]; Folic Acid affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of DNMT3B mRNA]; Folic Acid affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of VEGFA mRNA]; Folic Acid affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of VEGFA protein]; Folic Acid affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the methylation of CCL2 promoter]; Folic Acid affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the methylation of VEGFA promoter]

PMID:17118406 PMID:21867686 PMID:28475147

NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855

G

apolipoprotein L domain containing 1

decreases expression

ISO

Folic Acid results in decreased expression of APOLD1 mRNA

NCBI chr 4:169,499,728...169,557,075
Ensembl chr 4:169,549,679...169,559,176

G

apolipoprotein O

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of APOO mRNA

NCBI chr X:63,151,736...63,256,696
Ensembl chr X:63,151,814...63,256,690

G

amyloid beta precursor protein

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of APP mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of APP mRNA; Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in decreased expression of BAD protein modified form]; Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in decreased expression of BCL2 protein]; Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in decreased expression of BCL2L1 protein]; Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in decreased expression of IGF1R protein modified form]; Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in decreased expression of SIRT1 protein]; Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in decreased expression of SOD2 protein]; Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in increased expression of CASP12 protein modified form]; Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in increased expression of CASP3 protein modified form]; Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in increased expression of CASP9 protein modified form]; Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in increased expression of CYCS protein]; Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in increased expression of FADD protein]; Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in increased expression of FAS protein]
APP protein affects the reaction [Folic Acid affects the expression of DNMT1 mRNA]; APP protein affects the reaction [Folic Acid affects the expression of DNMT3B mRNA]; APP protein affects the reaction [Folic Acid affects the expression of DNMT3B protein]; pyrimidin-2-one beta-ribofuranoside inhibits the reaction [Folic Acid results in decreased expression of APP protein]

PMID:20938992 PMID:22206623 PMID:26492244 PMID:29068127

NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971

G

amyloid beta precursor protein binding protein 2

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of APPBP2 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of APPBP2 mRNA

PMID:22206623 PMID:25629700

NCBI chr10:70,555,212...70,597,267
Ensembl chr10:70,555,212...70,597,193

G

adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of APPL1 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of APPL1 mRNA

PMID:22206623 PMID:25629700

NCBI chr16:2,125,234...2,173,457
Ensembl chr16:2,125,234...2,173,421

G

adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of APPL2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of APPL2 gene
Folic Acid results in decreased expression of APPL2 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr 7:22,019,480...22,072,386
Ensembl chr 7:22,022,963...22,072,385

G

adenine phosphoribosyl transferase

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of APRT mRNA]

NCBI chr19:67,534,737...67,537,027

G

aquaporin 10

decreases expression

ISO

Folic Acid results in decreased expression of AQP10 mRNA

NCBI chr 2:177,699,717...177,704,620
Ensembl chr 2:177,700,943...177,704,495

G

aquaporin 11

decreases expression

ISO

Folic Acid results in decreased expression of AQP11 mRNA

NCBI chr 1:161,457,752...161,467,918
Ensembl chr 1:161,457,754...161,467,945

G

aquaporin 12A

increases expression

ISO

Folic Acid results in increased expression of AQP12 mRNA

NCBI chr 9:101,001,939...101,007,425
Ensembl chr 9:101,001,939...101,007,425

G

aquaporin 2

decreases expression

ISO

Folic Acid results in decreased expression of AQP2 mRNA

NCBI chr 7:132,590,286...132,595,321
Ensembl chr 7:132,590,225...132,595,319

G

aquaporin 3 (Gill blood group)

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AQP3 mRNA

NCBI chr 5:61,035,165...61,040,683
Ensembl chr 5:61,035,166...61,040,685

G

aquaporin 4

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AQP4 mRNA

NCBI chr18:6,782,389...6,799,034
Ensembl chr18:6,782,389...6,799,098

G

aquaporin 5

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AQP5 mRNA

NCBI chr 7:132,601,528...132,605,060
Ensembl chr 7:132,601,059...132,605,062

G

aquaporin 7

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AQP7 mRNA

NCBI chr 5:60,968,495...60,982,618
Ensembl chr 5:60,967,558...60,982,618

G

aquaporin 8

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AQP8 mRNA

NCBI chr 1:187,424,314...187,430,243
Ensembl chr 1:187,424,417...187,430,242

G

aquaporin 9

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of AQP9 mRNA

NCBI chr 8:80,678,027...80,718,273
Ensembl chr 8:80,678,030...80,717,240

G

aquarius intron-binding spliceosomal factor

decreases expression

ISO

Folic Acid results in decreased expression of AQR mRNA

NCBI chr 3:121,329,287...121,399,375
Ensembl chr 3:121,329,289...121,399,321

G

androgen receptor

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of AR mRNA

NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467

G

A-Raf proto-oncogene, serine/threonine kinase

decreases expression

ISO

Folic Acid results in decreased expression of ARAF mRNA

NCBI chr X:3,780,932...3,845,919
Ensembl chr X:3,780,932...3,792,611

G

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ARAP1 mRNA

NCBI chr 1:165,160,701...165,226,219
Ensembl chr 1:165,160,678...165,226,218

G

activity-regulated cytoskeleton-associated protein

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ARC gene

NCBI chr 7:108,444,959...108,448,413
Ensembl chr 7:108,444,692...108,451,220

G

amphiregulin

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AREG mRNA
[Folic Acid deficiency co-treated with Methotrexate] results in increased expression of AREG mRNA

PMID:20938992 PMID:24657277

NCBI chr14:17,256,384...17,265,641
Ensembl chr14:17,256,384...17,265,641

G

apoptosis resistant E3 ubiquitin protein ligase 1

multiple interactions
decreases expression

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of AREL1 mRNA]
Folic Acid results in decreased expression of AREL1 mRNA

PMID:21867686 PMID:22206623

NCBI chr 6:110,296,072...110,348,751
Ensembl chr 6:110,296,072...110,320,832

G

ARF GTPase 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ARF1 gene
Folic Acid results in decreased expression of ARF1 mRNA

PMID:20938992 PMID:25629700

NCBI chr10:44,497,543...44,513,994

G

ARF GTPase 4

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of ARF4 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ARF4 mRNA

PMID:22206623 PMID:25629700

NCBI chr16:1,903,238...1,920,012
Ensembl chr16:1,903,371...1,920,011

G

ARF GTPase 6

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of ARF6 mRNA
Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ARF6 mRNA]

PMID:22206623 PMID:25629700

NCBI chr 6:93,589,777...93,590,925
Ensembl chr 6:93,569,234...93,610,536

G

ARF GTPase activating protein 1

decreases expression

ISO

Folic Acid results in decreased expression of ARFGAP1 mRNA

NCBI chr 3:188,462,125...188,477,515
Ensembl chr 3:188,465,648...188,511,078

G

ARF GTPase activating protein 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ARFGAP3 mRNA

NCBI chr 7:116,312,996...116,359,300
Ensembl chr 7:116,313,001...116,359,592

G

ARF guanine nucleotide exchange factor 1

decreases expression

ISO

Folic Acid results in decreased expression of ARFGEF1 mRNA

NCBI chr 5:13,764,507...13,859,237
Ensembl chr 5:13,764,975...13,859,237

G

ARF guanine nucleotide exchange factor 2

decreases expression

ISO

Folic Acid results in decreased expression of ARFGEF2 mRNA

NCBI chr 3:175,966,575...176,052,715
Ensembl chr 3:175,966,579...176,052,713

G

ARFGEF family member 3

decreases expression

ISO

Folic Acid results in decreased expression of ARFGEF3 mRNA

NCBI chr 1:15,058,574...15,223,742
Ensembl chr 1:15,058,579...15,223,742

G

ARF interacting protein 1

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ARFIP1 mRNA
Folic Acid results in decreased expression of ARFIP1 mRNA

PMID:22206623 PMID:25629700

NCBI chr 2:172,141,862...172,224,464
Ensembl chr 2:172,141,859...172,221,280

G

ARF interacting protein 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ARFIP2 mRNA

NCBI chr 1:169,387,484...169,392,290
Ensembl chr 1:169,387,485...169,392,166

G

arginase 1

multiple interactions

ISO

Folic Acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of ARG1 mRNA]

NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:22,295,322...22,307,713

G

arginase 2

multiple interactions

ISO

[Folic Acid deficiency co-treated with Methotrexate] results in increased expression of ARG2 mRNA

NCBI chr 6:103,669,001...103,694,375
Ensembl chr 6:103,668,988...103,694,375

G

arginine and glutamate rich 1

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ARGLU1 mRNA]

NCBI chr16:87,455,097...87,479,148
Ensembl chr16:87,455,113...87,479,148

G

Rho GTPase activating protein 10

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ARHGAP10 mRNA

NCBI chr19:47,352,783...47,614,532
Ensembl chr19:47,352,276...47,614,531

G

Rho GTPase activating protein 11A

multiple interactions

ISO

[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of ARHGAP11A mRNA

NCBI chr 3:121,045,187...121,071,985
Ensembl chr 3:121,045,187...121,061,468

G

Rho GTPase activating protein 12

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ARHGAP12 mRNA

NCBI chr17:56,284,282...56,397,630
Ensembl chr17:56,284,286...56,397,563

G

Rho GTPase activating protein 15

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ARHGAP15 mRNA

NCBI chr 3:48,382,945...49,002,213
Ensembl chr 3:48,382,904...49,011,378

G

Rho GTPase activating protein 17

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ARHGAP17 mRNA

NCBI chr 1:187,238,675...187,328,093
Ensembl chr 1:187,238,380...187,327,936

G

Rho GTPase activating protein 22

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ARHGAP22 mRNA

NCBI chr16:8,480,222...8,637,823
Ensembl chr16:8,479,956...8,637,822

G

Rho GTPase activating protein 23

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ARHGAP23 mRNA

NCBI chr10:82,891,021...82,993,230
Ensembl chr10:82,890,853...82,993,228

G

Rho GTPase activating protein 25

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ARHGAP25 mRNA

NCBI chr 4:121,454,151...121,532,293
Ensembl chr 4:121,454,151...121,552,913

G

Rho GTPase activating protein 26

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ARHGAP26 mRNA

NCBI chr18:30,702,602...31,489,047
Ensembl chr18:31,089,787...31,489,047

G

Rho GTPase activating protein 28

decreases expression

ISO

Folic Acid results in decreased expression of ARHGAP28 mRNA

NCBI chr 9:115,277,849...115,444,789
Ensembl chr 9:115,279,734...115,445,008

G

Rho GTPase activating protein 29

affects expression
decreases expression

ISO

Folic Acid affects the expression of ARHGAP29 mRNA
Folic Acid results in decreased expression of ARHGAP29 mRNA

PMID:17320366 PMID:25629700

NCBI chr 2:212,744,626...212,816,710
Ensembl chr 2:212,755,803...212,986,729

G

Rho GTPase activating protein 30

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ARHGAP30 mRNA

NCBI chr13:86,354,448...86,376,552
Ensembl chr13:86,354,547...86,376,888

G

Rho GTPase activating protein 31

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ARHGAP31 gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of ARHGAP31 mRNA]

PMID:20938992 PMID:22206623

NCBI chr11:75,544,176...75,657,087
Ensembl chr11:75,544,040...75,661,076

G

Rho GTPase activating protein 32

increases expression

ISO

Folic Acid results in increased expression of ARHGAP32 mRNA

NCBI chr 8:38,679,368...38,939,960
Ensembl chr 8:38,684,484...38,939,960

G

Rho GTPase activating protein 35

multiple interactions
decreases expression
increases activity

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ARHGAP35 mRNA]
AG 1879 inhibits the reaction [Folic Acid results in increased activity of ARHGAP35 protein]; ARHGAP35 protein affects the reaction [Folic Acid results in decreased activity of RHOA protein]
Folic Acid results in decreased expression of ARHGAP35 mRNA

PMID:22206623 PMID:23178654 PMID:25629700

NCBI chr 1:86,330,566...86,447,414
Ensembl chr 1:86,330,566...86,447,414

G

Rho GTPase activating protein 8

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ARHGAP8 mRNA

NCBI chr 7:117,723,512...117,782,031
Ensembl chr 7:117,730,578...117,782,030

G

Rho GTPase activating protein 9

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ARHGAP9 mRNA

NCBI chr 7:65,034,023...65,042,336
Ensembl chr 7:65,034,144...65,042,336

G

Rho GDP dissociation inhibitor alpha

multiple interactions
increases expression

ISO
EXP

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ARHGDIA mRNA
[Folic Acid deficiency co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of ARHGDIA protein
Folic Acid results in increased expression of ARHGDIA mRNA

PMID:19566968 PMID:20938992 PMID:25629700

NCBI chr10:106,352,858...106,356,347
Ensembl chr10:106,353,491...106,356,347

G

Rho guanine nucleotide exchange factor 10 like

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ARHGEF10L mRNA

NCBI chr 5:158,075,370...158,218,358
Ensembl chr 5:158,075,370...158,180,685

G

Rho guanine nucleotide exchange factor 11

decreases expression

ISO

Folic Acid results in decreased expression of ARHGEF11 mRNA

NCBI chr 2:175,372,269...175,493,852
Ensembl chr 2:175,372,290...175,493,852

G

Rho guanine nucleotide exchange factor 12

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ARHGEF12 mRNA

NCBI chr 8:52,247,047...52,373,158
Ensembl chr 8:52,247,047...52,372,376

G

Rho guanine nucleotide exchange factor 16

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ARHGEF16 mRNA]

NCBI chr 5:170,126,573...170,148,624
Ensembl chr 5:170,126,575...170,148,624

G

Rho guanine nucleotide exchange factor 17

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ARHGEF17 mRNA]

NCBI chr 1:164,642,690...164,702,241
Ensembl chr 1:164,642,690...164,702,241

G

Rho guanine nucleotide exchange factor 19

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ARHGEF19 mRNA

NCBI chr 5:158,818,840...158,837,196
Ensembl chr 5:158,818,932...158,837,196

G

Rho/Rac guanine nucleotide exchange factor 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ARHGEF2 mRNA

NCBI chr 2:176,358,909...176,416,178
Ensembl chr 2:176,358,904...176,417,646

G

Rho guanine nucleotide exchange factor 26

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ARHGEF26 mRNA
Folic Acid results in decreased expression of ARHGEF26 mRNA

PMID:22206623 PMID:25629700

NCBI chr 2:148,889,405...149,000,538
Ensembl chr 2:148,889,423...149,000,538

G

Rho guanine nucleotide exchange factor 28

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ARHGEF28 mRNA

NCBI chr 2:30,998,292...31,294,757
Ensembl chr 2:30,998,295...31,294,853

G

Rho guanine nucleotide exchange factor 33

decreases expression

ISO

Folic Acid results in decreased expression of ARHGEF33 mRNA

NCBI chr 6:20,303,731...20,469,968
Ensembl chr 6:20,311,451...20,466,319

G

Rho guanine nucleotide exchange factor 4

increases expression

ISO

Folic Acid results in increased expression of ARHGEF4 mRNA

NCBI chr 9:44,357,716...44,500,959
Ensembl chr 9:44,357,736...44,501,550

G

Rho guanine nucleotide exchange factor 40

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ARHGEF40 mRNA

NCBI chr15:27,146,155...27,170,012
Ensembl chr15:27,146,197...27,170,012

G

Rho guanine nucleotide exchange factor 5

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ARHGEF5 mRNA]

NCBI chr 4:73,087,240...73,112,311
Ensembl chr 4:73,087,240...73,112,311

G

Rac/Cdc42 guanine nucleotide exchange factor 6

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ARHGEF6 mRNA

NCBI chr X:140,182,734...140,302,812
Ensembl chr X:140,182,734...140,344,458

G

Rho guanine nucleotide exchange factor 7

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ARHGEF7 mRNA

NCBI chr16:84,373,123...84,484,759
Ensembl chr16:84,373,123...84,484,597

G

AT-rich interaction domain 1A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ARID1A mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ARID1A gene

PMID:20938992 PMID:22206623

NCBI chr 5:151,192,014...151,269,291
Ensembl chr 5:151,192,014...151,265,386

G

AT-rich interaction domain 1B

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of and results in decreased expression of ARID1B; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ARID1B gene

NCBI chr 1:47,973,199...48,328,793
Ensembl chr 1:47,973,997...48,328,793

G

AT-rich interaction domain 3A

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of ARID3A; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ARID3A gene; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ARID3A mRNA

NCBI chr 7:10,403,161...10,431,551
Ensembl chr 7:10,405,631...10,427,926

G

AT-rich interaction domain 4A

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ARID4A gene

NCBI chr 6:95,258,429...95,335,987
Ensembl chr 6:95,258,429...95,329,840

G

AT-rich interaction domain 5B

decreases expression

ISO

Folic Acid results in decreased expression of ARID5B mRNA

NCBI chr20:20,305,693...20,489,689
Ensembl chr20:20,306,712...20,489,686

G

ariadne RBR E3 ubiquitin protein ligase 2

decreases expression

ISO

Folic Acid results in decreased expression of ARIH2 mRNA

NCBI chr 8:118,175,267...118,234,425
Ensembl chr 8:118,175,267...118,234,284

G

ARF like GTPase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ARL1 mRNA

NCBI chr 7:25,007,401...25,018,572
Ensembl chr 7:25,006,981...25,019,319

G

ARF like GTPase 10

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ARL10 gene

NCBI chr17:10,035,320...10,043,732
Ensembl chr17:10,035,320...10,043,981

G

ARF like GTPase 11

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ARL11 mRNA

NCBI chr15:39,659,404...39,661,651
Ensembl chr15:39,656,050...39,664,105

G

ARF like GTPase 13B

decreases expression

ISO

Folic Acid results in decreased expression of ARL13B mRNA

NCBI chr11:13,597,538...13,663,681
Ensembl chr11:13,597,538...13,663,546

G

ARF like GTPase 14 effector protein

decreases expression

ISO

Folic Acid results in decreased expression of ARL14EP mRNA

NCBI chr 3:113,896,731...113,908,994
Ensembl chr 3:113,898,076...113,908,833

G

ARF like GTPase 15

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ARL15 mRNA

NCBI chr 2:47,171,377...47,555,666
Ensembl chr 2:47,094,900...47,555,666

G

ARF like GTPase 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ARL2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ARL2 gene

PMID:20938992 PMID:22206623

NCBI chr 1:212,863,422...212,875,425
Ensembl chr 1:212,863,423...212,875,373

G

ARF like GTPase 2 binding protein

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ARL2BP mRNA]

NCBI chr19:10,342,895...10,352,529
Ensembl chr19:10,342,895...10,352,514

G

ARF like GTPase 3

decreases expression

ISO

Folic Acid results in decreased expression of ARL3 mRNA

NCBI chr 1:255,342,078...255,388,087
Ensembl chr 1:255,342,076...255,388,279

G

ARF like GTPase 4A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ARL4A mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ARL4A gene

PMID:20938992 PMID:22206623

NCBI chr 6:62,809,287...62,811,297
Ensembl chr 6:62,804,548...62,820,760

G

ARF like GTPase 4C

affects expression
multiple interactions

ISO

Folic Acid affects the expression of ARL4C mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ARL4C mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ARL4C mRNA

PMID:17320366 PMID:20938992 PMID:22206623

NCBI chr 9:96,748,075...96,751,510
Ensembl chr 9:96,745,069...96,752,772

G

ARF like GTPase 4D

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of ARL4D mRNA
Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of ARL4D mRNA]

PMID:22206623 PMID:25629700

NCBI chr10:87,092,276...87,103,079
Ensembl chr10:87,077,523...87,106,199

G

ARF like GTPase 5A

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ARL5A mRNA]

NCBI chr 3:57,287,599...57,312,488
Ensembl chr 3:57,289,846...57,312,488

G

ARF like GTPase 5C

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ARL5C mRNA

NCBI chr10:83,481,540...83,492,915
Ensembl chr10:83,481,540...83,488,406

G

ARL6 interacting reticulophagy regulator 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ARL6IP1 mRNA

NCBI chr 1:181,864,717...181,874,232
Ensembl chr 1:181,864,746...181,874,232

G

ARF like GTPase 6 interacting protein 4

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ARL6IP4 gene
Folic Acid results in increased expression of ARL6IP4 mRNA

PMID:20938992 PMID:25629700

NCBI chr12:38,140,566...38,142,711
Ensembl chr12:38,140,550...38,142,724

G

ARF like GTPase 6 interacting protein 5

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ARL6IP5 mRNA

NCBI chr 4:131,365,320...131,395,311
Ensembl chr 4:131,367,289...131,400,130

G

ARF like GTPase 6 interacting protein 6

multiple interactions
increases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ARL6IP6 mRNA
Folic Acid results in increased expression of ARL6IP6 mRNA

PMID:22206623 PMID:25629700

NCBI chr 3:58,098,978...58,126,962
Ensembl chr 3:58,099,408...58,126,957

G

ARF like GTPase 8A

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ARL8A mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ARL8A gene
Folic Acid results in decreased expression of ARL8A mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr13:49,137,632...49,146,633
Ensembl chr13:49,137,632...49,146,633

G

ARF like GTPase 9

decreases expression

ISO

Folic Acid results in decreased expression of ARL9 mRNA

NCBI chr14:31,511,845...31,521,038
Ensembl chr14:31,511,330...31,520,988

G

armadillo repeat containing 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ARMC1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ARMC1 gene

PMID:20938992 PMID:22206623

NCBI chr 2:103,524,333...103,568,355
Ensembl chr 2:103,524,333...103,568,355

G

armadillo repeat containing 5

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ARMC5 mRNA

NCBI chr 1:192,250,580...192,257,347
Ensembl chr 1:192,249,939...192,257,348

G

armadillo repeat containing 8

decreases expression

ISO

Folic Acid results in decreased expression of ARMC8 mRNA

NCBI chr 8:108,916,274...109,010,877
Ensembl chr 8:108,916,274...109,010,717

G

armadillo repeat containing 9

decreases expression

ISO

Folic Acid results in decreased expression of ARMC9 mRNA

NCBI chr 9:94,250,492...94,376,589
Ensembl chr 9:94,250,859...94,376,589

G

armadillo repeat containing, X-linked 3

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ARMCX3 mRNA
Folic Acid results in decreased expression of ARMCX3 mRNA

PMID:20938992 PMID:25629700

NCBI chr X:102,230,464...102,234,017
Ensembl chr X:102,219,848...102,263,297

G

armadillo repeat containing, X-linked 5

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of ARMCX5; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ARMCX5 gene; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ARMCX5 mRNA

NCBI chr X:103,501,552...103,505,978
Ensembl chr X:103,501,146...103,539,449

G

aryl hydrocarbon receptor nuclear translocator 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ARNT2 gene

NCBI chr 1:147,645,354...147,801,986
Ensembl chr 1:147,599,058...147,801,997

G

actin related protein 2/3 complex, subunit 1A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ARPC1A mRNA

NCBI chr12:14,616,245...14,639,052
Ensembl chr12:14,616,248...14,639,052

G

actin related protein 2/3 complex, subunit 1B

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ARPC1B mRNA]

NCBI chr12:14,595,939...14,609,501
Ensembl chr12:14,595,678...14,609,504

G

actin related protein 2/3 complex, subunit 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ARPC2 mRNA

NCBI chr 9:83,269,884...83,300,610
Ensembl chr 9:83,269,932...83,305,409

G

actin related protein 2/3 complex, subunit 3

multiple interactions
decreases expression

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ARPC3 mRNA]
Folic Acid results in decreased expression of ARPC3 mRNA

PMID:22206623 PMID:25629700

NCBI chr12:39,833,569...39,847,436
Ensembl chr12:39,833,569...39,847,436

G

actin related protein 2/3 complex, subunit 4

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ARPC4 mRNA]

NCBI chr 4:148,077,799...148,088,427
Ensembl chr 4:148,077,240...148,088,428

G

actin related protein 2/3 complex, subunit 5-like

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ARPC5L mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ARPC5L gene

PMID:20938992 PMID:22206623

NCBI chr 3:43,169,518...43,177,224
Ensembl chr 3:43,169,462...43,177,240
Ensembl chr 9:43,169,462...43,177,240

G

cAMP-regulated phosphoprotein 19

decreases expression

ISO

Folic Acid results in decreased expression of ARPP19 mRNA

NCBI chr 8:84,660,166...84,683,012
Ensembl chr 8:119,691,942...119,692,385
Ensembl chr 8:119,691,942...119,692,385

G

arrestin, beta 1

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of ARRB1 mRNA]

NCBI chr 1:163,249,654...163,321,711
Ensembl chr 1:163,250,157...163,340,859

G

arrestin domain containing 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ARRDC2 mRNA

NCBI chr16:18,635,883...18,640,019
Ensembl chr16:18,635,883...18,640,158

G

arrestin domain containing 3

multiple interactions
decreases expression

ISO

[Ethanol co-treated with Folic Acid] results in increased expression of ARRDC3 mRNA
Folic Acid results in decreased expression of ARRDC3 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ARRDC3 mRNA

PMID:22206623 PMID:23378141 PMID:25629700

NCBI chr 2:12,873,202...12,885,716
Ensembl chr 2:12,873,202...12,885,875

G

arrestin domain containing 4

decreases expression

ISO

Folic Acid results in decreased expression of ARRDC4 mRNA

NCBI chr 1:131,779,436...131,793,438
Ensembl chr 1:131,779,437...131,793,565

G

arylsulfatase A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ARSA mRNA

NCBI chr 7:122,422,971...122,426,971
Ensembl chr 7:122,422,982...122,428,401

G

arylsulfatase G

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ARSG mRNA

NCBI chr10:94,912,094...95,063,021
Ensembl chr10:94,913,152...95,042,447

G

ADP-ribosyltransferase 4

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ART4 mRNA

NCBI chr 4:171,468,415...171,482,435
Ensembl chr 4:171,471,534...171,481,868

G

ARVCF, delta catenin family member

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ARVCF gene

NCBI chr11:96,092,451...96,150,144
Ensembl chr11:96,092,451...96,150,163

G

arsenite methyltransferase

multiple interactions
decreases expression

ISO

Folic Acid promotes the reaction [Vitamin B 12 promotes the reaction [AS3MT protein results in increased methylation of Arsenic]]
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AS3MT mRNA
Folic Acid results in decreased expression of AS3MT mRNA

PMID:20049124 PMID:22206623 PMID:25629700

NCBI chr 1:255,536,879...255,569,245
Ensembl chr 1:255,537,109...255,569,249

G

N-acylsphingosine amidohydrolase 1

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of ASAH1 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ASAH1 mRNA

PMID:22206623 PMID:25629700

NCBI chr16:57,669,927...57,701,349
Ensembl chr16:57,669,750...57,718,305

G

N-acylsphingosine amidohydrolase 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ASAH2 mRNA

NCBI chr 1:239,278,994...239,386,598
Ensembl chr 1:239,278,994...239,382,024

G

ArfGAP with SH3 domain, ankyrin repeat and PH domain 1

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ASAP1 mRNA
Folic Acid results in decreased expression of ASAP1 mRNA

PMID:22206623 PMID:25629700

NCBI chr 7:97,675,354...97,982,523
Ensembl chr 7:97,675,354...97,982,024

G

ankyrin repeat and SOCS box containing 11

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ASB11 mRNA

NCBI chr X:33,646,389...33,669,790
Ensembl chr X:33,624,394...33,669,934

G

ankyrin repeat and SOCS box-containing 13

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ASB13 mRNA

NCBI chr17:71,474,531...71,493,238
Ensembl chr17:71,474,531...71,505,633

G

ankyrin repeat and SOCS box-containing 18

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ASB18 gene

NCBI chr 9:97,979,018...98,043,609
Ensembl chr 9:97,979,264...98,043,540

G

ankyrin repeat and SOCS box-containing 4

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ASB4 mRNA
Folic Acid results in decreased expression of ASB4 mRNA

PMID:20938992 PMID:21867686

NCBI chr 4:34,473,527...34,511,163
Ensembl chr 4:34,473,408...34,512,888

G

ankyrin repeat and SOCS box-containing 9

increases expression

ISO

Folic Acid results in increased expression of ASB9 mRNA

NCBI chr X:33,588,484...33,633,285
Ensembl chr X:33,588,484...33,624,397

G

activating signal cointegrator 1 complex subunit 1

decreases expression

ISO

Folic Acid results in decreased expression of ASCC1 mRNA

NCBI chr20:28,484,044...28,574,195
Ensembl chr20:28,483,956...28,574,200

G

activating signal cointegrator 1 complex subunit 2

multiple interactions
increases expression

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ASCC2 mRNA]
Folic Acid results in increased expression of ASCC2 mRNA

PMID:22206623 PMID:25629700

NCBI chr14:83,726,975...83,771,312
Ensembl chr14:83,727,049...83,771,316

G

anti-silencing function 1A histone chaperone

decreases expression

ISO

Folic Acid results in decreased expression of ASF1A mRNA

NCBI chr20:33,436,632...33,451,478
Ensembl chr20:33,436,707...33,449,639

G

anti-silencing function 1B histone chaperone

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of ASF1B; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ASF1B gene; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ASF1B mRNA
Folic Acid results in decreased expression of ASF1B mRNA
[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of ASF1B mRNA

PMID:20938992 PMID:24657277 PMID:25629700

NCBI chr19:41,085,786...41,100,352
Ensembl chr19:41,086,114...41,100,352

G

asialoglycoprotein receptor 1

decreases expression

ISO

Folic Acid results in decreased expression of ASGR1 mRNA

NCBI chr10:55,274,299...55,278,323
Ensembl chr10:55,274,706...55,278,322

G

asialoglycoprotein receptor 2

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of ASGR2 mRNA]

NCBI chr10:55,320,082...55,333,294
Ensembl chr10:55,320,091...55,333,263

G

ASH1 like histone lysine methyltransferase

decreases expression

ISO

Folic Acid results in decreased expression of ASH1L mRNA

NCBI chr 2:176,644,393...176,780,848
Ensembl chr 2:176,644,924...176,780,847

G

ASH2 like histone lysine methyltransferase complex subunit

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ASH2L gene
Folic Acid results in decreased expression of ASH2L mRNA

PMID:20938992 PMID:21867686

NCBI chr16:72,943,527...72,966,791
Ensembl chr16:72,944,949...72,967,839

G

acid sensing ion channel subunit 2

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ASIC2 gene
Folic Acid results in decreased expression of ASIC2 mRNA

PMID:20938992 PMID:21867686

NCBI chr10:66,368,308...67,438,237
Ensembl chr10:66,368,310...66,636,245

G

acid sensing ion channel subunit 3

increases expression

ISO

Folic Acid results in increased expression of ASIC3 mRNA

NCBI chr 4:11,652,946...11,657,415
Ensembl chr 4:11,652,946...11,657,367

G

agouti signaling protein

increases methylation

ISO

Folic Acid results in increased methylation of A gene

NCBI chr 3:163,933,768...164,021,377
Ensembl chr 3:164,015,903...164,021,378

G

argininosuccinate lyase

multiple interactions
decreases expression

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ASL mRNA]
Folic Acid results in decreased expression of ASL mRNA

PMID:22206623 PMID:25629700

NCBI chr12:32,295,779...32,313,257
Ensembl chr12:32,295,633...32,317,261

G

acetylserotonin O-methyltransferase-like

decreases expression

ISO

Folic Acid results in decreased expression of ASMTL mRNA

NCBI chr12:21,429,119...21,431,847
Ensembl chr12:21,429,171...21,431,847

G

asparagine synthetase (glutamine-hydrolyzing)

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ASNS gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ASNS mRNA]

PMID:20938992 PMID:22206623

NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:36,751,802...36,776,050

G

asparagine synthetase domain containing 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ASNSD1 mRNA

NCBI chr 9:55,618,799...55,631,064
Ensembl chr 9:55,618,799...55,631,064

G

aspartoacylase

decreases expression

ISO

Folic Acid results in decreased expression of ASPA mRNA

NCBI chr10:58,390,204...58,443,790
Ensembl chr10:58,379,410...58,443,769

G

asparaginase

multiple interactions
decreases expression

ISO

icariin inhibits the reaction [Folic Acid results in decreased expression of ASPG protein]

NCBI chr 6:136,997,832...137,017,417
Ensembl chr 6:136,998,023...137,017,417

G

aspartate-beta-hydroxylase

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ASPH mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ASPH gene
Folic Acid results in decreased expression of ASPH mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr 5:27,398,933...27,611,519
Ensembl chr 5:27,398,949...27,611,215

G

aspartate beta-hydroxylase domain containing 2

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of ASPHD2 mRNA]

NCBI chr12:49,908,539...49,919,060
Ensembl chr12:49,908,241...49,925,254

G

assembly factor for spindle microtubules

multiple interactions
decreases expression

ISO

[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of ASPM mRNA
Folic Acid results in decreased expression of ASPM mRNA

PMID:24657277 PMID:25629700

NCBI chr13:53,625,584...53,674,489
Ensembl chr13:53,625,584...53,674,489

G

ASPSCR1 tether for SLC2A4, UBX domain containing

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ASPSCR1 gene

NCBI chr10:106,450,600...106,488,231
Ensembl chr10:106,450,567...106,488,579

G

asparaginase and isoaspartyl peptidase 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ASRGL1 mRNA

NCBI chr 1:215,436,180...215,456,188
Ensembl chr 1:215,435,218...215,456,198

G

argininosuccinate synthase 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ASS1 mRNA

NCBI chr 3:35,144,765...35,194,632
Ensembl chr 3:35,144,999...35,194,627

G

ASXL transcriptional regulator 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ASXL1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ASXL1 gene

PMID:20938992 PMID:22206623

NCBI chr 3:162,273,828...162,341,742
Ensembl chr 3:162,273,828...162,341,742

G

ASXL transcriptional regulator 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ASXL2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ASXL2 gene

PMID:20938992 PMID:22206623

NCBI chr 6:32,090,497...32,234,487
Ensembl chr 6:32,145,607...32,227,851

G

ATPase family, AAA domain containing 2B

decreases expression

ISO

Folic Acid results in decreased expression of ATAD2B mRNA

NCBI chr 6:33,646,075...33,789,532
Ensembl chr 6:33,646,075...33,789,532

G

ATPase family, AAA domain containing 3A

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ATAD3A mRNA]

NCBI chr 5:171,632,545...171,652,725
Ensembl chr 5:171,632,547...171,652,725

G

ATCAY kinesin light chain interacting caytaxin

decreases expression

ISO

Folic Acid results in decreased expression of ATCAY mRNA

NCBI chr 7:9,138,485...9,162,249
Ensembl chr 7:9,138,587...9,163,370

G

arginyltransferase 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ATE1 gene

NCBI chr 1:194,391,843...194,514,284
Ensembl chr 1:194,391,843...194,511,348

G

activating transcription factor 2

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ATF2 gene
Folic Acid results in decreased expression of ATF2 mRNA

PMID:20938992 PMID:25629700

NCBI chr 3:79,125,814...79,202,896
Ensembl chr 3:79,126,705...79,202,745

G

activating transcription factor 3

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ATF3 mRNA; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ATF3 mRNA]
[Folic Acid deficiency co-treated with Methotrexate] results in increased expression of ATF3 mRNA

PMID:20938992 PMID:22206623 PMID:24657277

NCBI chr13:105,274,103...105,331,653
Ensembl chr13:105,282,440...105,295,750

G

activating transcription factor 5

multiple interactions
increases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ATF5 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ATF5 mRNA
Folic Acid results in increased expression of ATF5 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr 1:104,432,094...104,437,611
Ensembl chr 1:104,432,094...104,436,183

G

activating transcription factor 6 beta

affects expression
multiple interactions

ISO

Folic Acid affects the expression of ATF6B mRNA
[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ATF6B gene

PMID:17320366 PMID:20938992

NCBI chr20:4,095,534...4,103,534
Ensembl chr20:4,095,534...4,106,032

G

activating transcription factor 7

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ATF7 mRNA

NCBI chr 7:135,537,351...135,649,188
Ensembl chr 7:135,542,111...135,599,899

G

activating transcription factor 7 interacting protein

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ATF7IP gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ATF7IP mRNA]

PMID:20938992 PMID:22206623

NCBI chr 4:171,117,122...171,202,871
Ensembl chr 4:171,117,122...171,202,867

G

autophagy related 101

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATG101 mRNA

NCBI chr 7:134,277,223...134,286,387
Ensembl chr 7:134,272,847...134,286,379

G

autophagy related 12

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATG12 mRNA

NCBI chr18:41,638,841...41,649,311
Ensembl chr18:41,635,835...41,649,261

G

autophagy related 14

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ATG14 mRNA

NCBI chr15:23,275,457...23,306,817
Ensembl chr15:23,275,457...23,306,815

G

autophagy related 16-like 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATG16L1 mRNA

NCBI chr 9:95,869,839...95,905,354
Ensembl chr 9:95,869,865...95,905,357

G

autophagy related 3

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ATG3 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ATG3 mRNA
Folic Acid results in decreased expression of ATG3 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr11:69,130,948...69,159,280
Ensembl chr11:69,121,952...69,159,280

G

autophagy related 4D, cysteine peptidase

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of ATG4D mRNA]

NCBI chr 8:28,083,902...28,093,491
Ensembl chr 8:28,083,936...28,093,491

G

autophagy related 5

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATG5 mRNA

NCBI chr20:49,380,835...49,471,826
Ensembl chr20:49,380,813...49,471,821

G

autophagy related 7

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATG7 mRNA

NCBI chr 4:149,390,000...149,597,534
Ensembl chr 4:149,391,390...149,598,319

G

autophagy related 9A

decreases expression

ISO

Folic Acid results in decreased expression of ATG9A mRNA

NCBI chr 9:84,126,071...84,136,723
Ensembl chr 9:84,126,071...84,136,666

G

autophagy related 9B

decreases expression

ISO

Folic Acid results in decreased expression of ATG9B mRNA

NCBI chr 4:11,678,548...11,686,097
Ensembl chr 4:11,678,299...11,686,079

G

5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATIC mRNA

NCBI chr 9:80,614,311...80,634,360
Ensembl chr 9:80,614,283...80,635,756

G

atlastin GTPase 1

decreases expression

ISO

Folic Acid results in decreased expression of ATL1 mRNA

NCBI chr 6:94,113,149...94,210,955
Ensembl chr 6:94,112,877...94,211,219

G

ATM serine/threonine kinase

affects expression

ISO

Folic Acid affects the expression of ATM mRNA

NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629

G

ATM interactor

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of ATMIN mRNA]

NCBI chr19:61,905,343...61,922,443
Ensembl chr19:61,905,144...61,922,443

G

atrophin 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATN1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ATN1 gene

PMID:20938992 PMID:22206623

NCBI chr 4:159,240,573...159,254,378
Ensembl chr 4:159,237,562...159,254,418

G

atonal bHLH transcription factor 1

decreases expression

ISO

Folic Acid results in decreased expression of ATOH1 mRNA

NCBI chr 4:95,241,933...95,244,028
Ensembl chr 4:95,241,933...95,244,019

G

atonal bHLH transcription factor 7

decreases expression

ISO

Folic Acid results in decreased expression of ATOH7 mRNA

NCBI chr20:25,529,528...25,529,977
Ensembl chr20:25,528,906...25,530,368

G

atos homolog B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ATOSB mRNA

NCBI chr 5:62,056,654...62,070,338
Ensembl chr 5:62,056,654...62,064,613

G

antioxidant 1 copper chaperone

increases expression

ISO

Folic Acid results in increased expression of ATOX1 mRNA

NCBI chr10:40,065,525...40,080,627
Ensembl chr10:40,065,527...40,080,585

G

ATPase phospholipid transporting 10A (putative)

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ATP10A gene

NCBI chr 1:118,692,456...118,866,117
Ensembl chr 1:118,692,478...118,866,114

G

ATPase phospholipid transporting 10D (putative)

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ATP10D mRNA

NCBI chr14:36,265,696...36,366,460
Ensembl chr14:36,265,696...36,366,460

G

ATPase phospholipid transporting 11A

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of ATP11A mRNA]

NCBI chr16:83,359,884...83,469,807
Ensembl chr16:83,359,884...83,469,767

G

ATPase phospholipid transporting 11B (putative)

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ATP11B mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of and results in decreased expression of ATP11B; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ATP11B gene
Folic Acid results in decreased expression of ATP11B mRNA

PMID:20938992 PMID:25629700

NCBI chr 2:120,513,535...120,619,249
Ensembl chr 2:120,513,552...120,619,249

G

ATPase 13A3

decreases expression

ISO

Folic Acid results in decreased expression of ATP13A3 mRNA

NCBI chr11:83,860,725...83,946,899
Ensembl chr11:83,870,218...83,944,662

G

ATPase 13A4

decreases expression

ISO

Folic Acid results in decreased expression of ATP13A4 mRNA

NCBI chr11:84,727,014...84,864,747
Ensembl chr11:84,731,041...84,864,747

G

ATPase 13A5

decreases expression

ISO

Folic Acid results in decreased expression of ATP13A5 mRNA

NCBI chr11:84,881,196...85,020,597
Ensembl chr11:84,881,230...85,020,593

G

ATPase Na+/K+ transporting subunit alpha 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATP1A1 mRNA

NCBI chr 2:191,709,311...191,737,414
Ensembl chr 2:191,709,311...191,737,425

G

ATPase Na+/K+ transporting subunit alpha 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ATP1A2 mRNA

NCBI chr13:87,261,964...87,286,911
Ensembl chr13:87,261,968...87,286,911

G

ATPase Na+/K+ transporting subunit alpha 3

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ATP1A3 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ATP1A3 gene
Folic Acid results in decreased expression of ATP1A3 mRNA

PMID:20938992 PMID:25629700

NCBI chr 1:89,700,645...89,729,782
Ensembl chr 1:89,700,649...89,729,825

G

ATPase Na+/K+ transporting subunit beta 1

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATP1B1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ATP1B1 gene
Folic Acid results in decreased expression of ATP1B1 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr13:79,319,708...79,340,226
Ensembl chr13:79,319,706...79,340,549

G

ATPase Na+/K+ transporting subunit beta 3

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of ATP1B3 mRNA
Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ATP1B3 mRNA]

PMID:22206623 PMID:25629700

NCBI chr 8:105,789,824...105,821,151
Ensembl chr 8:65,253,361...65,254,304
Ensembl chr 8:65,253,361...65,254,304

G

ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ATP2A2 gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ATP2A2 mRNA]

PMID:20938992 PMID:22206623

NCBI chr12:39,733,519...39,782,942
Ensembl chr12:39,733,458...39,782,934

G

ATPase plasma membrane Ca2+ transporting 2

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ATP2B2 mRNA
Folic Acid results in decreased expression of ATP2B2 mRNA

PMID:20938992 PMID:25629700

NCBI chr 4:148,450,207...148,763,653
Ensembl chr 4:148,450,207...148,696,239

G

ATPase secretory pathway Ca2+ transporting 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATP2C2 mRNA

NCBI chr19:64,662,729...64,719,998
Ensembl chr19:64,662,715...64,719,996

G

ATP synthase F1 subunit alpha

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATP5F1A mRNA

NCBI chr18:73,567,537...73,575,473
Ensembl chr18:73,567,526...73,575,922

G

ATP synthase F1 subunit beta

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ATP5F1B gene
Folic Acid results in decreased expression of ATP5F1B

PMID:20938992 PMID:24275386

NCBI chr 7:1,100,058...1,106,461
Ensembl chr 7:1,099,860...1,106,462

G

ATP synthase F1 subunit delta

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATP5F1D mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ATP5F1D gene

PMID:20938992 PMID:22206623

NCBI chr 7:10,211,260...10,218,989
Ensembl chr 7:10,211,262...10,216,583

G

ATP synthase F1 subunit epsilon

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATP5F1E mRNA

NCBI chr 3:183,677,270...183,680,172
Ensembl chr 3:183,677,273...183,680,214

G

ATP synthase inhibitory factor subunit 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATP5IF1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ATP5IF1 mRNA

PMID:20938992 PMID:22206623

NCBI chr 5:150,022,960...150,026,677
Ensembl chr 5:150,022,960...150,026,677

G

ATP synthase membrane subunit c locus 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATP5MC3 mRNA

NCBI chr 3:79,218,014...79,220,664
Ensembl chr 3:79,218,014...79,220,664

G

ATP synthase membrane subunit e

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATP5ME mRNA

NCBI chr14:1,464,788...1,465,989
Ensembl chr14:1,464,800...1,465,988

G

ATP synthase membrane subunit f

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATP5MF mRNA

NCBI chr12:14,535,435...14,542,007
Ensembl chr12:14,522,832...14,542,709

G

ATP synthase membrane subunit G

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of ATP5MG mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATP5MG mRNA

PMID:22206623 PMID:25629700

NCBI chr 8:54,122,457...54,130,407
Ensembl chr 8:54,122,457...54,132,831

G

ATP synthase membrane subunit j

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATP5MJ mRNA

NCBI chr 6:136,839,890...136,845,640
Ensembl chr 1:177,906,475...177,907,045
Ensembl chr 1:177,906,475...177,907,045

G

ATP synthase membrane subunit K

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATP5MK mRNA

NCBI chr 1:255,915,255...255,922,185
Ensembl chr 1:255,915,259...255,922,106
Ensembl chr10:255,915,259...255,922,106

G

ATP synthase peripheral stalk-membrane subunit b

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATP5PB mRNA

NCBI chr 2:196,112,459...196,123,737
Ensembl chr 2:196,112,108...196,124,387

G

ATP synthase peripheral stalk subunit d

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATP5PD mRNA

NCBI chr10:101,156,673...101,161,926
Ensembl chr10:101,156,673...101,162,954

G

ATP synthase peripheral stalk subunit F6

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATP5PF mRNA

NCBI chr11:37,368,045...37,375,721
Ensembl chr11:37,368,042...37,375,466

G

ATP synthase peripheral stalk subunit OSCP

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATP5PO mRNA

NCBI chr11:44,651,171...44,657,483
Ensembl chr11:44,651,173...44,657,520

G

ATPase H+ transporting accessory protein 1

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ATP6AP1 mRNA]

NCBI chr X:157,231,243...157,238,323
Ensembl chr X:157,225,327...157,238,323

G

ATPase H+ transporting accessory protein 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATP6AP2 mRNA

NCBI chr X:12,856,708...12,883,670
Ensembl chr X:12,855,859...12,905,875

G

ATPase H+ transporting V0 subunit a1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ATP6V0A1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ATP6V0A1 mRNA

PMID:20938992 PMID:22206623

NCBI chr10:86,436,089...86,490,185
Ensembl chr10:86,436,141...86,490,181

G

ATPase H+ transporting V0 subunit a2

decreases expression

ISO

Folic Acid results in decreased expression of ATP6V0A2 mRNA

NCBI chr12:37,608,211...37,640,860
Ensembl chr12:37,472,813...37,640,860

G

ATPase H+ transporting V0 subunit a4

increases expression

ISO

Folic Acid results in increased expression of ATP6V0A4 mRNA

NCBI chr 4:67,727,145...67,809,092
Ensembl chr 4:67,727,145...67,809,092

G

ATPase H+ transporting V0 subunit B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATP6V0B mRNA

NCBI chr 5:136,708,823...136,710,339
Ensembl chr 5:136,708,823...136,716,828

G

ATPase H+ transporting V0 subunit C

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATP6V0C mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ATP6V0C gene
Folic Acid results in decreased expression of ATP6V0C mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr10:13,700,764...13,707,147
Ensembl chr10:13,700,764...13,706,245

G

ATPase H+ transporting V0 subunit D1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATP6V0D1 mRNA

NCBI chr19:50,313,268...50,357,248
Ensembl chr19:50,313,273...50,357,395

G

ATPase H+ transporting V0 subunit D2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ATP6V0D2 mRNA

NCBI chr 5:38,133,151...38,182,245
Ensembl chr 5:38,133,158...38,182,245

G

ATPase H+ transporting V0 subunit e1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATP6V0E mRNA

NCBI chr10:16,984,084...17,007,156
Ensembl chr10:16,984,084...17,028,858

G

ATPase, H+ transporting V0 subunit e2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ATP6V0E2 mRNA

NCBI chr 4:78,815,771...78,818,919
Ensembl chr 4:78,813,129...78,819,680

G

ATPase H+ transporting V1 subunit A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ATP6V1A mRNA

NCBI chr11:70,066,800...70,120,603
Ensembl chr11:70,035,134...70,120,603

G

ATPase H+ transporting V1 subunit B2

decreases expression

ISO

Folic Acid results in decreased expression of ATP6V1B2 mRNA

NCBI chr16:25,384,254...25,408,388
Ensembl chr16:25,384,257...25,408,839

G

ATPase H+ transporting V1 subunit C1

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ATP6V1C1 mRNA]

NCBI chr 7:71,719,326...71,757,191
Ensembl chr 7:71,719,404...71,757,184

G

ATPase H+ transporting V1 subunit C2

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ATP6V1C2 gene
Folic Acid results in increased expression of ATP6V1C2 mRNA

PMID:20938992 PMID:25629700

NCBI chr 6:45,809,269...45,872,914
Ensembl chr 6:45,809,271...45,848,747

G

ATPase H+ transporting V1 subunit D

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of ATP6V1D mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATP6V1D mRNA

PMID:22206623 PMID:25629700

NCBI chr 6:103,389,778...103,405,346
Ensembl chr 6:103,389,783...103,405,346

G

ATPase H+ transporting V1 subunit G1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATP6V1G1 mRNA

NCBI chr 5:81,976,959...81,983,139
Ensembl chr 5:81,977,015...81,985,930

G

ATPase H+ transporting V1 subunit G2

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of ATP6V1G2 mRNA]

NCBI chr20:3,592,374...3,595,986
Ensembl chr20:3,592,364...3,595,475

G

ATPase copper transporting alpha

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATP7A mRNA

NCBI chr X:75,159,635...75,267,094
Ensembl chr X:75,159,782...75,267,093

G

ATPase copper transporting beta

decreases expression

ISO

Folic Acid results in decreased expression of ATP7B mRNA

NCBI chr16:76,654,725...76,726,092
Ensembl chr16:76,653,660...76,728,801

G

ATPase phospholipid transporting 8B1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ATP8B1 gene

NCBI chr18:60,286,605...60,427,862
Ensembl chr18:60,288,464...60,427,027

G

ATPase phospholipid transporting 8B2

decreases expression

ISO

Folic Acid results in decreased expression of ATP8B2 mRNA

NCBI chr 2:177,676,205...177,699,575
Ensembl chr 2:177,676,208...177,699,575

G

ATPase phospholipid transporting 9A (putative)

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ATP9A mRNA]

NCBI chr 3:177,779,203...177,886,431
Ensembl chr 3:177,779,203...178,023,661

G

ATP synthase mitochondrial F1 complex assembly factor 1

decreases expression

ISO

Folic Acid results in decreased expression of ATPAF1 mRNA

NCBI chr 5:134,503,164...134,530,323
Ensembl chr 5:134,499,687...134,530,321

G

ATP synthase mitochondrial F1 complex assembly factor 2

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of ATPAF2 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATPAF2 mRNA

PMID:22206623 PMID:25629700

NCBI chr10:45,705,157...45,721,282
Ensembl chr10:45,697,027...45,721,383

G

ATP synthase c subunit lysine N-methyltransferase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATPSCKMT mRNA

NCBI chr 2:84,313,991...84,329,195
Ensembl chr 2:84,313,921...84,329,194

G

ATR serine/threonine kinase

decreases expression

ISO

Folic Acid results in decreased expression of ATR mRNA

NCBI chr 8:105,306,299...105,403,742
Ensembl chr 8:105,306,305...105,403,718

G

attractin like 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ATRNL1 mRNA
Folic Acid results in decreased expression of ATRNL1 mRNA

PMID:20938992 PMID:25629700

NCBI chr 1:266,676,051...267,216,847
Ensembl chr 1:266,675,852...267,216,842

G

ATRX, chromatin remodeler

decreases expression

ISO

Folic Acid results in decreased expression of ATRX mRNA

NCBI chr X:74,916,548...75,062,880
Ensembl chr X:74,916,548...75,062,880

G

ataxin 1

multiple interactions

ISO

[Ethanol co-treated with Folic Acid] results in increased expression of ATXN1 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATXN1 mRNA

PMID:22206623 PMID:23378141

NCBI chr17:18,943,397...19,354,751
Ensembl chr17:19,208,200...19,356,790

G

ataxin 10

increases expression
multiple interactions

ISO

Folic Acid results in increased expression of ATXN10 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ATXN10 mRNA

PMID:22206623 PMID:25629700

NCBI chr 7:118,321,516...118,444,967
Ensembl chr 7:118,319,490...118,445,636

G

ataxin 1 like

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATXN1L mRNA

NCBI chr19:54,609,852...54,621,024
Ensembl chr19:54,609,132...54,680,582

G

ataxin 2-like

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATXN2L mRNA

NCBI chr 1:190,508,878...190,526,263
Ensembl chr 1:190,508,878...190,520,579

G

ataxin 7

decreases expression

ISO

Folic Acid results in decreased expression of ATXN7 mRNA

NCBI chr15:13,547,859...13,693,311
Ensembl chr15:13,547,862...13,693,526

G

ataxin 7-like 1

decreases expression

ISO

Folic Acid results in decreased expression of ATXN7L1 mRNA

NCBI chr 6:55,487,309...55,709,751
Ensembl chr 6:55,649,362...55,701,996

G

ataxin 7-like 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATXN7L2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ATXN7L2 gene

PMID:20938992 PMID:22206623

NCBI chr 2:198,527,066...198,535,899
Ensembl chr 2:198,527,066...198,534,062

G

ataxin 7-like 3B

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of ATXN7L3B mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATXN7L3B mRNA

PMID:22206623 PMID:25629700

NCBI chr 7:50,208,666...50,212,190
Ensembl chr 7:50,208,676...50,212,190

G

AU RNA binding methylglutaconyl-CoA hydratase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AUH mRNA

NCBI chr17:12,481,396...12,576,748
Ensembl chr17:12,481,416...12,602,587

G

AUP1, lipid droplet regulating VLDL assembly factor

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of AUP1 mRNA]

NCBI chr 4:117,118,035...117,121,063
Ensembl chr 4:117,117,999...117,121,061

G

aurora kinase A

multiple interactions

ISO

[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of AURKA mRNA

NCBI chr 3:181,546,742...181,562,890
Ensembl chr 3:181,546,742...181,562,771

G

aurora kinase B

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of AURKB; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of AURKB gene; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AURKB mRNA
Folic Acid results in decreased expression of AURKB mRNA

PMID:20938992 PMID:25629700

NCBI chr10:54,243,116...54,249,675
Ensembl chr10:54,242,850...54,252,285

G

activator of transcription and developmental regulator AUTS2

multiple interactions
affects expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AUTS2 mRNA
Folic Acid affects the expression of AUTS2 mRNA

PMID:20938992 PMID:26547318

NCBI chr12:29,739,138...30,830,386
Ensembl chr12:29,740,523...30,830,386

G

apoptosis and caspase activation inhibitor

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of AVEN mRNA]

NCBI chr 3:119,753,395...119,886,009
Ensembl chr 3:119,872,661...119,886,008

G

AVL9 cell migration associated

decreases expression

ISO

Folic Acid results in decreased expression of AVL9 mRNA

NCBI chr 4:87,291,062...87,338,537
Ensembl chr 4:87,291,798...87,331,916

G

arginine vasopressin

decreases expression

ISO

Folic Acid results in decreased expression of AVP mRNA

PMID:25006883 PMID:25629700

NCBI chr 3:138,246,544...138,248,522
Ensembl chr 3:138,246,554...138,248,522

G

arginine vasopressin-induced 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AVPI1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AVPI1 mRNA

PMID:20938992 PMID:22206623

NCBI chr 1:250,879,530...250,885,448
Ensembl chr 1:250,879,530...250,885,704

G

arginine vasopressin receptor 2

increases expression

ISO

Folic Acid results in increased expression of AVPR2 mRNA

NCBI chr X:156,785,009...156,787,477
Ensembl chr X:156,785,139...156,787,477

G

axin 1

multiple interactions
decreases expression

ISO

[Folic Acid co-treated with Vitamin B 12 co-treated with Betaine co-treated with Choline] results in increased methylation of AXIN1 gene
Folic Acid results in decreased expression of AXIN1 mRNA

PMID:16868943 PMID:25629700

NCBI chr10:15,667,894...15,720,092
Ensembl chr10:15,667,958...15,720,092

G

axin 2

multiple interactions
decreases expression

ISO

[Folic Acid co-treated with sodium arsenite] results in increased methylation of AXIN2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of AXIN2 gene
Folic Acid results in decreased expression of AXIN2 mRNA

PMID:20938992 PMID:22959928 PMID:25629700

NCBI chr10:94,393,379...94,426,579
Ensembl chr10:94,395,909...94,426,575

G

Axl receptor tyrosine kinase

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of AXL mRNA
Folic Acid results in decreased expression of AXL mRNA

PMID:22206623 PMID:25629700

NCBI chr 1:90,392,864...90,424,123
Ensembl chr 1:90,392,864...90,424,009

G

5-azacytidine induced 2

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AZI2 mRNA
Folic Acid results in decreased expression of AZI2 mRNA

PMID:22206623 PMID:25629700

NCBI chr 8:126,651,268...126,674,795
Ensembl chr 8:126,651,206...126,676,182

G

antizyme inhibitor 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AZIN1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of AZIN1 gene

PMID:20938992 PMID:22206623

NCBI chr 7:71,539,711...71,566,515
Ensembl chr 7:71,539,711...71,566,515

G

antizyme inhibitor 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of AZIN2 mRNA

NCBI chr 5:146,568,187...146,594,777
Ensembl chr 5:146,565,437...146,594,777

G

beta-2 microglobulin

affects expression

ISO

Folic Acid affects the expression of B2M mRNA

NCBI chr 3:129,549,236...129,555,354
Ensembl chr 3:129,549,318...129,555,356

G

beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of B3GALNT1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of B3GALNT1 mRNA

PMID:20938992 PMID:22206623

NCBI chr 2:156,157,234...156,187,037
Ensembl chr 2:156,156,265...156,188,404

G

beta-1,3-N-acetylgalactosaminyltransferase 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of B3GALNT2 mRNA

NCBI chr17:56,030,409...56,072,952
Ensembl chr17:56,030,409...56,072,952

G

Beta-1,3-galactosyltransferase 2

decreases expression

ISO

Folic Acid results in decreased expression of B3GALT2 mRNA

NCBI chr13:57,939,724...57,948,735
Ensembl chr13:57,930,539...57,956,539

G

Beta-1,3-galactosyltransferase 4

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of B3GALT4 mRNA

NCBI chr20:4,937,974...4,939,549
Ensembl chr20:4,937,674...4,939,885

G

Beta-1,3-galactosyltransferase 6

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of B3GALT6 mRNA
Folic Acid results in decreased expression of B3GALT6 mRNA

PMID:20938992 PMID:25629700

NCBI chr 5:171,866,428...171,868,564
Ensembl chr 5:171,864,094...171,874,789

G

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of B3GNT2 gene

NCBI chr14:101,009,682...101,034,507
Ensembl chr14:100,967,131...101,043,412

G

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3

increases expression

ISO

Folic Acid results in increased expression of B3GNT3 mRNA

NCBI chr16:18,434,114...18,444,851
Ensembl chr16:18,435,378...18,444,738

G

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of B3GNT8 mRNA

NCBI chr 1:90,263,387...90,266,292
Ensembl chr 1:90,263,827...90,270,287

G

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9

decreases expression

ISO

Folic Acid results in decreased expression of B3GNT9 mRNA

NCBI chr19:50,039,649...50,042,206
Ensembl chr19:50,030,866...50,043,339

G

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1

decreases expression

ISO

Folic Acid results in decreased expression of B3GNTL1 mRNA

NCBI chr10:107,363,036...107,431,988
Ensembl chr10:107,371,442...107,431,908

G

beta-1,4-N-acetyl-galactosaminyl transferase 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of B4GALNT1 gene

NCBI chr 7:64,873,909...64,881,512
Ensembl chr 7:64,874,022...64,881,516

G

beta-1,4-N-acetyl-galactosaminyl transferase 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of B4GALNT2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of B4GALNT2 gene

PMID:20938992 PMID:22206623

NCBI chr10:81,298,338...81,324,738
Ensembl chr10:81,299,421...81,382,557

G

beta-1,4-N-acetyl-galactosaminyl transferase 4

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of B4GALNT4 gene

NCBI chr 1:205,600,989...205,611,889
Ensembl chr 1:205,600,989...205,611,889

G

beta-1,4-galactosyltransferase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of B4GALT1 mRNA

NCBI chr 5:60,731,601...60,778,456
Ensembl chr 5:60,731,602...60,778,445

G

beta-1,4-galactosyltransferase 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of B4GALT2 mRNA

NCBI chr 5:136,697,981...136,707,783
Ensembl chr 5:136,697,981...136,710,422

G

beta-1,4-galactosyltransferase 4

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of B4GALT4 mRNA
Folic Acid results in decreased expression of B4GALT4 mRNA

PMID:22206623 PMID:25629700

NCBI chr11:75,501,358...75,527,291
Ensembl chr11:75,501,366...75,527,177

G

beta-1,4-galactosyltransferase 6

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of B4GALT6 mRNA; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of B4GALT6 mRNA]

PMID:20938992 PMID:22206623

NCBI chr18:12,233,350...12,290,204
Ensembl chr18:12,233,351...12,290,204

G

beta-1,4-glucuronyltransferase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of B4GAT1 mRNA

NCBI chr 1:211,772,644...211,774,866
Ensembl chr 1:211,772,606...211,775,442

G

B9 domain containing 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of B9D1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of B9D1 mRNA

PMID:20938992 PMID:22206623

NCBI chr10:46,685,410...46,698,580
Ensembl chr10:46,686,133...46,695,428

G

B9 domain containing 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of B9D2 mRNA

NCBI chr 1:90,315,472...90,323,143
Ensembl chr 1:90,317,200...90,323,175

G

BRISC and BRCA1 A complex member 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BABAM2 mRNA

NCBI chr 6:30,089,065...30,467,508
Ensembl chr 6:30,071,611...30,467,341

G

beta-secretase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BACE1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of BACE1 gene

PMID:20938992 PMID:22206623

NCBI chr 8:55,038,842...55,061,138
Ensembl chr 8:55,038,823...55,064,918

G

beta-secretase 2

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of BACE2 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BACE2 mRNA

PMID:22206623 PMID:25629700

NCBI chr11:50,176,852...50,258,948
Ensembl chr11:50,176,621...50,259,008

G

BTB domain and CNC homolog 1

multiple interactions
decreases expression

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of BACH1 mRNA]
Folic Acid results in decreased expression of BACH1 mRNA

PMID:22206623 PMID:25629700

NCBI chr11:40,425,721...40,461,118
Ensembl chr11:40,425,664...40,461,277

G

BTB domain and CNC homolog 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BACH2 gene

NCBI chr 5:51,428,802...51,779,030
Ensembl chr 5:51,434,870...51,774,234

G

BCL2-associated agonist of cell death

multiple interactions

ISO

Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in decreased expression of BAD protein modified form]

NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034

G

BAG cochaperone 2

decreases expression

ISO

Folic Acid results in decreased expression of BAG2 mRNA

NCBI chr 9:43,465,993...43,476,637
Ensembl chr 9:43,465,995...43,476,752

G

BAG cochaperone 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BAG3 mRNA

NCBI chr 1:192,533,460...192,557,281
Ensembl chr 1:192,475,828...192,557,280

G

BAG cochaperone 5

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BAG5 mRNA

NCBI chr 6:136,589,623...136,593,278
Ensembl chr 6:136,584,741...136,598,492

G

BAG cochaperone 6

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of and results in decreased expression of BAG6; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of BAG6 gene
Folic Acid results in increased expression of BAG6 mRNA

PMID:20938992 PMID:25629700

NCBI chr20:3,680,607...3,693,329
Ensembl chr20:3,680,607...3,693,329

G

BAH domain and coiled-coil containing 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of BAHCC1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BAHCC1 gene
Folic Acid results in decreased expression of BAHCC1 mRNA

PMID:20938992 PMID:25629700

NCBI chr10:106,020,534...106,081,698
Ensembl chr10:106,020,575...106,080,285

G

bromo adjacent homology domain containing 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of BAHD1 gene
Folic Acid results in decreased expression of BAHD1 mRNA

PMID:20938992 PMID:25629700

NCBI chr 3:126,341,853...126,368,281
Ensembl chr 3:126,345,371...126,368,278

G

BAR/IMD domain containing adaptor protein 2

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of BAIAP2; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BAIAP2 gene; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BAIAP2 mRNA
Folic Acid results in decreased expression of BAIAP2 mRNA

PMID:20938992 PMID:25629700

NCBI chr10:105,721,371...105,788,549
Ensembl chr10:105,721,417...105,788,549

G

BAR/IMD domain containing adaptor protein 2 like 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BAIAP2L2 mRNA

NCBI chr 7:112,704,798...112,731,691
Ensembl chr 7:112,704,682...112,731,127

G

BCL2-antagonist/killer 1

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of BAK1 mRNA]
Folic Acid inhibits the reaction [Camptothecin results in decreased expression of BAK1 mRNA]; Folic Acid inhibits the reaction [Doxorubicin results in decreased expression of BAK1 mRNA]; Folic Acid inhibits the reaction [Methyl Methanesulfonate results in increased expression of BAK1 mRNA]

PMID:22206623 PMID:30581319

NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974

G

BMP and activin membrane-bound inhibitor

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of BAMBI; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BAMBI gene; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BAMBI mRNA

NCBI chr17:58,816,438...58,821,003
Ensembl chr17:58,816,442...58,821,247

G

barrier to autointegration nuclear assembly factor 1

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of BANF1 mRNA]

NCBI chr 1:212,101,523...212,103,568
Ensembl chr 1:212,101,523...212,103,552

G

BRCA1 associated deubiquitinase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of BAP1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of BAP1 gene

PMID:20938992 PMID:22206623

NCBI chr16:6,453,126...6,461,952
Ensembl chr16:6,452,974...6,461,952

G

BRCA1 associated RING domain 1

decreases expression

ISO

Folic Acid results in decreased expression of BARD1 mRNA

NCBI chr 9:80,069,960...80,144,167
Ensembl chr 9:80,069,960...80,176,873

G

BarH-like homeobox 1

decreases expression

ISO

Folic Acid results in decreased expression of BARHL1 mRNA

NCBI chr 3:32,639,283...32,646,605
Ensembl chr 3:32,638,644...32,646,605

G

BarH-like homeobox 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of BARHL2 gene

NCBI chr14:3,485,309...3,490,206
Ensembl chr14:3,485,309...3,490,197

G

BARX homeobox 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of BARX1 gene
Folic Acid results in decreased expression of BARX1 mRNA

PMID:20938992 PMID:25629700

NCBI chr17:16,196,764...16,200,239
Ensembl chr17:16,196,764...16,200,239

G

BARX homeobox 2

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BARX2 gene
Folic Acid results in decreased expression of BARX2 mRNA

PMID:20938992 PMID:25629700

NCBI chr 8:38,509,277...38,576,978
Ensembl chr 8:38,509,277...38,576,978

G

basic leucine zipper ATF-like transcription factor

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BATF mRNA

NCBI chr 6:111,084,717...111,107,052
Ensembl chr 6:111,084,717...111,107,052

G

basic leucine zipper ATF-like transcription factor 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BATF2 mRNA

NCBI chr 1:212,897,076...212,905,740
Ensembl chr 1:212,875,148...212,905,831

G

BCL2 associated X, apoptosis regulator

affects expression
multiple interactions
increases expression

ISO
EXP

Folic Acid affects the expression of BAX mRNA
Folic Acid affects the reaction [Homocysteine affects the expression of BAX mRNA]; Folic Acid affects the reaction [Homocysteine affects the expression of BAX protein]; Folic Acid inhibits the reaction [aluminum maltolate results in increased expression of BAX protein]; Folic Acid inhibits the reaction [Camptothecin results in decreased expression of BAX mRNA]
Folic Acid results in increased expression of BAX mRNA; Folic Acid results in increased expression of BAX protein
[Folic Acid co-treated with Isoflavones] results in decreased expression of BAX protein; [Methionine co-treated with Betaine co-treated with Choline co-treated with Folic Acid] inhibits the reaction [Carbon Tetrachloride results in increased expression of BAX mRNA]; [Vitamin E co-treated with Folic Acid] affects the expression of BAX protein; Folic Acid inhibits the reaction [Homocysteine results in increased expression of BAX mRNA]; Folic Acid inhibits the reaction [Nicotine results in increased expression of BAX protein]
Decitabine inhibits the reaction [Folic Acid results in increased expression of BAX mRNA]; Folic Acid inhibits the reaction [sodium arsenite results in increased expression of BAX protein]; Nicorandil inhibits the reaction [Folic Acid results in increased expression of BAX protein]; nilotinib inhibits the reaction [Folic Acid results in increased expression of BAX protein]; PTHLH protein inhibits the reaction [Folic Acid results in increased expression of BAX protein]; trichostatin A inhibits the reaction [Folic Acid results in increased expression of BAX mRNA]; Trimetazidine inhibits the reaction [Folic Acid results in increased expression of BAX protein]

PMID:16361273 PMID:16672315 PMID:16933212 PMID:20060418 PMID:27113042 More...

NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429

G

bromodomain adjacent to zinc finger domain, 1B

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BAZ1B gene

NCBI chr12:27,068,541...27,126,511
Ensembl chr12:27,068,541...27,126,511

G

bromodomain adjacent to zinc finger domain, 2A

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of BAZ2A gene
Folic Acid results in decreased expression of BAZ2A mRNA

PMID:20938992 PMID:25629700

NCBI chr 7:1,107,377...1,145,507
Ensembl chr 7:1,107,796...1,145,507

G

bromodomain adjacent to zinc finger domain, 2B

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of BAZ2B mRNA]

NCBI chr 3:64,792,984...65,034,547
Ensembl chr 3:64,794,001...65,001,781

G

Bcl-2 binding component 3

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BBC3 gene

NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:86,141,603...86,150,666

G

Bardet-Biedl syndrome 1

decreases expression

ISO

Folic Acid results in decreased expression of BBS1 mRNA

NCBI chr 1:211,614,195...211,633,504
Ensembl chr 1:211,615,533...211,633,468

G

Bardet-Biedl syndrome 4

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BBS4 gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of BBS4 mRNA]

PMID:20938992 PMID:22206623

NCBI chr 8:68,627,739...68,661,232
Ensembl chr 8:68,627,656...68,661,358

G

Bardet-Biedl syndrome 7

decreases expression

ISO

Folic Acid results in decreased expression of BBS7 mRNA

NCBI chr 2:121,362,884...121,402,473
Ensembl chr 2:121,362,885...121,402,473

G

BBX high mobility group box domain containing

decreases expression

ISO

Folic Acid results in decreased expression of BBX mRNA

NCBI chr11:63,850,034...64,097,700
Ensembl chr11:63,850,018...64,093,265

G

basal cell adhesion molecule (Lutheran blood group)

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BCAM mRNA

NCBI chr 1:88,542,971...88,557,358
Ensembl chr 1:88,542,972...88,557,888

G

brevican

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BCAN gene

NCBI chr 2:175,752,333...175,765,766
Ensembl chr 2:175,752,336...175,765,314

G

B-cell receptor-associated protein 29

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BCAP29 mRNA

NCBI chr 6:53,910,209...53,950,206
Ensembl chr 6:53,910,216...53,949,963

G

B-cell receptor-associated protein 31

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BCAP31 mRNA

NCBI chr X:156,548,911...156,581,002
Ensembl chr X:156,548,911...156,579,371

G

BCAR1 scaffold protein, Cas family member

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BCAR1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BCAR1 gene

PMID:20938992 PMID:22206623

NCBI chr19:56,588,500...56,623,190
Ensembl chr19:56,588,500...56,623,190

G

BCAR3 adaptor protein, NSP family member

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BCAR3 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BCAR3 gene

PMID:20938992 PMID:22206623

NCBI chr 2:213,209,907...213,323,305
Ensembl chr 2:213,209,893...213,323,302

G

branched chain amino acid transaminase 1

decreases expression

ISO

Folic Acid results in decreased expression of BCAT1 mRNA

NCBI chr 4:179,695,662...179,777,973
Ensembl chr 4:179,695,662...179,777,288

G

branched chain amino acid transaminase 2

decreases expression

ISO

Folic Acid results in decreased expression of BCAT2 mRNA

NCBI chr 1:105,175,157...105,196,474
Ensembl chr 1:105,176,977...105,196,463

G

BRCA2 and CDKN1A interacting protein

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of BCCIP mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BCCIP mRNA

PMID:22206623 PMID:25629700

NCBI chr 1:197,942,535...197,954,948
Ensembl chr 1:197,942,190...197,956,378

G

BCDIN3 domain containing RNA methyltransferase

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of BCDIN3D gene

NCBI chr 7:132,484,404...132,488,998
Ensembl chr 7:132,484,431...132,488,998

G

butyrylcholinesterase

multiple interactions

EXP
ISO

Folic Acid inhibits the reaction [Homocysteine results in decreased activity of BCHE protein]
[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of BCHE mRNA

PMID:16442260 PMID:24657277

NCBI chr 2:160,607,289...160,699,760
Ensembl chr 2:160,606,288...160,699,760

G

branched chain keto acid dehydrogenase E1 subunit beta

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BCKDHB mRNA

NCBI chr 8:93,725,277...93,907,799
Ensembl chr 8:93,725,275...93,907,798

G

branched chain ketoacid dehydrogenase kinase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BCKDK mRNA

NCBI chr 1:191,945,809...191,950,480
Ensembl chr 1:191,946,471...191,953,453

G

BCL10, immune signaling adaptor

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BCL10 mRNA
Folic Acid results in decreased expression of BCL10 mRNA

PMID:22206623 PMID:25629700

NCBI chr 2:237,501,181...237,510,821
Ensembl chr 2:237,501,134...237,511,829

G

BCL11 transcription factor A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of BCL11A mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BCL11A gene

PMID:20938992 PMID:22206623

NCBI chr14:102,230,147...102,325,289
Ensembl chr14:102,231,113...102,325,623

G

BCL11 transcription factor B

decreases expression

ISO

Folic Acid results in decreased expression of BCL11B mRNA

NCBI chr 6:132,598,968...132,692,123
Ensembl chr 6:132,598,968...132,691,301

G

BCL2, apoptosis regulator

affects expression
increases expression
decreases expression
multiple interactions

ISO
EXP

Folic Acid affects the expression of BCL2 mRNA
Folic Acid results in increased expression of BCL2 mRNA
Folic Acid deficiency results in decreased expression of BCL2 protein
[Folic Acid co-treated with Methyl Methanesulfonate] results in increased expression of BCL2 mRNA; Folic Acid affects the reaction [Homocysteine affects the expression of BCL2 mRNA]; Folic Acid affects the reaction [Homocysteine affects the expression of BCL2 protein]; Folic Acid inhibits the reaction [aluminum maltolate results in decreased expression of BCL2 protein]; Folic Acid inhibits the reaction [Camptothecin results in decreased expression of BCL2 mRNA]; Folic Acid inhibits the reaction [Doxorubicin results in decreased expression of BCL2 mRNA]
Folic Acid results in decreased expression of BCL2 mRNA; Folic Acid results in decreased expression of BCL2 protein
Folic Acid affects the expression of BCL2 protein
[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of BCL2; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BCL2 gene; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BCL2 mRNA; Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in decreased expression of BCL2 protein]; Folic Acid inhibits the reaction [sodium arsenite results in decreased expression of BCL2 protein]; PTHLH protein inhibits the reaction [Folic Acid results in increased expression of BCL2 protein]; Trimetazidine inhibits the reaction [Folic Acid results in decreased expression of BCL2 protein]
[Carbon Tetrachloride co-treated with Folic Acid] results in decreased expression of BCL2 mRNA; [Folic Acid co-treated with Isoflavones] results in increased expression of BCL2 protein; [Methionine co-treated with Betaine co-treated with Choline co-treated with Folic Acid] inhibits the reaction [Carbon Tetrachloride results in decreased expression of BCL2 protein]; [Vitamin E co-treated with Folic Acid] affects the expression of BCL2 protein; Folic Acid affects the reaction [[Homocysteine co-treated with Sodium Glutamate] affects the expression of BCL2 mRNA]; Folic Acid affects the reaction [[Homocysteine co-treated with Sodium Glutamate] affects the expression of BCL2 protein]; Folic Acid inhibits the reaction [Methionine results in decreased methylation of BCL2 gene]; Folic Acid inhibits the reaction [Methionine results in increased expression of BCL2 mRNA]; Folic Acid inhibits the reaction [Methionine results in increased expression of BCL2 protein]; Folic Acid inhibits the reaction [Nicotine results in decreased expression of BCL2 protein]

PMID:16611376 PMID:16672315 PMID:16933212 PMID:18156304 PMID:20060418 More...

NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900

G

BCL2-related protein A1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BCL2A1B mRNA

NCBI chr 8:98,596,806...98,604,890
Ensembl chr 8:98,596,650...98,604,890

G

Bcl2-like 1

decreases expression
multiple interactions
increases expression

ISO

Folic Acid results in decreased expression of BCL2L1 protein
Folic Acid inhibits the reaction [Camptothecin results in decreased expression of BCL2L1 mRNA]; Folic Acid inhibits the reaction [Doxorubicin results in decreased expression of BCL2L1 mRNA]
Folic Acid results in increased expression of BCL2L1 mRNA
Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in decreased expression of BCL2L1 protein]; TNF protein affects the reaction [Folic Acid results in decreased expression of BCL2L1 protein]

PMID:16595132 PMID:25629700 PMID:29068127 PMID:30581319

NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907

G

Bcl2-like 10

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of BCL2L10 mRNA]

NCBI chr 8:84,987,833...84,993,878
Ensembl chr 8:84,987,833...84,993,872

G

Bcl2-like 11

affects expression

ISO

Folic Acid affects the expression of BCL2L11 mRNA

NCBI chr 3:135,820,042...135,857,330
Ensembl chr 3:135,817,562...135,960,695

G

Bcl2 like 12

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of BCL2L12 mRNA
Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of BCL2L12 mRNA]

PMID:22206623 PMID:25629700

NCBI chr 1:104,608,753...104,617,472
Ensembl chr 1:104,608,753...104,617,472

G

Bcl2-like 14

multiple interactions
increases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BCL2L14 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BCL2L14 mRNA
Folic Acid results in increased expression of BCL2L14 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr 4:168,948,919...168,989,450
Ensembl chr 4:168,948,946...168,990,079

G

Bcl2-like 2

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BCL2L2 mRNA
Folic Acid results in decreased expression of BCL2L2 mRNA

PMID:20938992 PMID:25629700

NCBI chr15:32,326,686...32,337,834
Ensembl chr15:32,326,020...32,335,379

G

BCL3, transcription coactivator

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BCL3 mRNA

NCBI chr 1:88,599,321...88,613,555
Ensembl chr 1:88,599,321...88,614,368

G

BCL6B, transcription repressor

decreases expression

ISO

Folic Acid results in decreased expression of BCL6B mRNA

NCBI chr10:55,439,566...55,444,631
Ensembl chr10:55,432,382...55,444,631

G

BAF chromatin remodeling complex subunit BCL7A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BCL7A mRNA

NCBI chr12:38,872,851...38,904,770
Ensembl chr12:38,872,851...38,904,770

G

BAF chromatin remodeling complex subunit BCL7C

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of BCL7C mRNA]

NCBI chr 1:191,703,432...191,754,751
Ensembl chr 1:191,691,089...191,754,641

G

BCL9, transcription coactivator

decreases expression

ISO

Folic Acid results in decreased expression of BCL9 mRNA

NCBI chr 2:187,449,425...187,475,241
Ensembl chr 2:187,449,425...187,475,241

G

BCL9 like

decreases expression

ISO

Folic Acid results in decreased expression of BCL9L mRNA

NCBI chr 8:53,708,770...53,738,880
Ensembl chr 8:53,708,770...53,737,395

G

BCL2-associated transcription factor 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BCLAF1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of BCLAF1 gene

PMID:20938992 PMID:22206623

NCBI chr 1:16,904,572...16,937,106
Ensembl chr 1:16,914,118...16,936,801

G

BCLAF1 and THRAP3 family member 3

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of BCLAF3 mRNA
Folic Acid results in decreased expression of BCLAF3 mRNA

PMID:21867686 PMID:22206623

NCBI chr X:39,065,842...39,137,521
Ensembl chr X:39,072,840...39,137,448

G

BCL6 co-repressor

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of BCOR mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BCOR gene
Folic Acid results in decreased expression of BCOR mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr X:13,282,431...13,402,254
Ensembl chr X:13,360,376...13,402,254

G

BCL6 co-repressor-like 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of BCORL1 mRNA
Folic Acid results in decreased expression of BCORL1 mRNA

PMID:20938992 PMID:25629700

NCBI chr X:132,394,703...132,462,414
Ensembl chr X:132,397,069...132,461,976

G

BCR activator of RhoGEF and GTPase

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of BCR mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of BCR mRNA

PMID:21867686 PMID:22206623

NCBI chr20:13,468,732...13,596,333
Ensembl chr20:13,468,732...13,596,333

G

BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of BCS1L mRNA

NCBI chr 9:83,614,045...83,618,052
Ensembl chr 9:83,613,975...83,618,257

G

3-hydroxybutyrate dehydrogenase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BDH1 mRNA

NCBI chr11:82,806,125...82,848,133
Ensembl chr11:82,807,503...82,842,636

G

brain-derived neurotrophic factor

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BDNF gene
Folic Acid results in increased expression of BDNF mRNA; Folic Acid results in increased expression of BDNF protein

PMID:20938992 PMID:30920123

NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657

G

beclin 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BECN1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of BECN1 gene

PMID:20938992 PMID:22206623

NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002

G

bestrophin 1

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BEST1 mRNA
Folic Acid results in increased expression of BEST1 mRNA

PMID:20938992 PMID:25629700

NCBI chr 1:216,054,395...216,071,012
Ensembl chr 1:216,054,395...216,070,974

G

Bet1 golgi vesicular membrane trafficking protein

decreases expression

ISO

Folic Acid results in decreased expression of BET1 mRNA

NCBI chr 4:33,070,892...33,081,162
Ensembl chr 4:33,070,891...33,081,164

G

Bet1 golgi vesicular membrane trafficking protein-like

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BET1L mRNA

NCBI chr 1:205,361,041...205,365,036
Ensembl chr 1:205,361,041...205,364,706

G

brain expressed X-linked 1

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of BEX2 mRNA
[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BEX2 mRNA

PMID:20938992 PMID:25629700

NCBI chr X:104,010,639...104,012,143
Ensembl chr X:104,010,371...104,011,236

G

brain expressed X-linked 2

multiple interactions

ISO

[Ethanol co-treated with Folic Acid] results in decreased expression of BEX1 mRNA
[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BEX1 mRNA

PMID:20938992 PMID:23378141

NCBI chr X:103,811,458...103,812,986
Ensembl chr X:103,808,935...103,812,092

G

brain expressed X-linked 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BEX3 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BEX3 mRNA

PMID:20938992 PMID:22206623

NCBI chr X:104,064,896...104,066,425
Ensembl chr X:104,064,515...104,075,906

G

brain expressed, X-linked 4

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BEX4 mRNA

NCBI chr X:103,923,609...103,925,041
Ensembl chr X:103,923,338...103,925,496

G

bifunctional apoptosis regulator

affects expression
decreases expression

ISO

Folic Acid affects the expression of BFAR mRNA
Folic Acid results in decreased expression of BFAR mRNA

PMID:16361273 PMID:25629700

NCBI chr10:2,059,189...2,092,207
Ensembl chr10:2,059,058...2,094,183

G

beaded filament structural protein 1

increases expression

ISO

Folic Acid results in increased expression of BFSP1 mRNA

NCBI chr 3:151,648,588...151,706,153
Ensembl chr 3:151,648,588...151,682,837

G

basic helix-loop-helix family, member a15

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BHLHA15 mRNA

NCBI chr12:15,534,123...15,538,299
Ensembl chr12:15,534,123...15,538,515

G

basic helix-loop-helix family, member a9

decreases expression

ISO

Folic Acid results in decreased expression of BHLHA9 mRNA

NCBI chr10:62,011,787...62,012,908
Ensembl chr10:62,011,787...62,012,908

G

basic helix-loop-helix family, member e40

multiple interactions

ISO

[Ethanol co-treated with Folic Acid] results in increased expression of BHLHE40 mRNA; [Folic Acid deficiency co-treated with Methotrexate] results in increased expression of BHLHE40 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BHLHE40 mRNA

PMID:22206623 PMID:23378141 PMID:24657277

NCBI chr 4:143,174,450...143,180,150
Ensembl chr 4:143,174,048...143,180,783

G

basic helix-loop-helix family, member e41

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BHLHE41 gene
Folic Acid results in increased expression of BHLHE41 mRNA
[Ethanol co-treated with Folic Acid] results in increased expression of BHLHE41 mRNA

PMID:20938992 PMID:23378141 PMID:25629700

NCBI chr 4:180,565,003...180,569,415
Ensembl chr 4:180,565,003...180,569,355

G

betaine-homocysteine S-methyltransferase

multiple interactions
decreases expression
increases expression

ISO
EXP

[Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in decreased expression of BHMT mRNA; [Choline deficiency co-treated with Folic Acid deficiency] affects the expression of BHMT mRNA
Folic Acid deficiency results in decreased expression of BHMT mRNA; Folic Acid deficiency results in decreased expression of BHMT protein
Folic Acid results in increased expression of BHMT mRNA; Folic Acid results in increased expression of BHMT protein
Folic Acid results in decreased expression of BHMT mRNA

PMID:21840474 PMID:23439872 PMID:25384423 PMID:29127188 PMID:30920123

NCBI chr 2:26,594,852...26,614,429
Ensembl chr 2:26,594,854...26,614,715

G

BicC family RNA binding protein 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BICC1 mRNA
Folic Acid results in decreased expression of BICC1 mRNA

PMID:20938992 PMID:25629700

NCBI chr20:17,448,745...17,685,887
Ensembl chr20:17,448,765...17,685,885

G

BICD cargo adaptor 1

decreases expression

ISO

Folic Acid results in decreased expression of BICD1 mRNA

NCBI chr 4:184,208,891...184,362,840
Ensembl chr 4:184,210,363...184,357,391

G

BH3 interacting domain death agonist

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BID mRNA
Folic Acid results in decreased expression of BID mRNA

PMID:22206623 PMID:25629700

NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:155,785,377...155,808,275

G

bridging integrator 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of BIN1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BIN1 gene

PMID:20938992 PMID:22206623

NCBI chr18:24,282,840...24,341,461
Ensembl chr18:24,283,801...24,341,458

G

bridging integrator 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BIN3 mRNA

NCBI chr15:51,583,474...51,622,329
Ensembl chr15:51,583,481...51,622,329

G

baculoviral IAP repeat-containing 2

increases expression
decreases expression
multiple interactions

ISO
EXP

Folic Acid results in increased expression of BIRC2 mRNA; Folic Acid results in increased expression of BIRC2 protein
Folic Acid results in decreased expression of BIRC2 mRNA
[Carbon Tetrachloride co-treated with Folic Acid] results in decreased expression of BIRC2 mRNA

PMID:15211800 PMID:18156304 PMID:25629700

NCBI chr 8:13,253,697...13,273,672
Ensembl chr 8:13,253,706...13,271,911

G

baculoviral IAP repeat-containing 3

affects expression
decreases expression
multiple interactions

ISO

Folic Acid affects the expression of BIRC3 mRNA
Folic Acid results in decreased expression of BIRC3 mRNA
[Folic Acid deficiency co-treated with Methotrexate] results in increased expression of BIRC3 mRNA

PMID:16361273 PMID:21867686 PMID:24657277

NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:13,285,703...13,298,590

G

baculoviral IAP repeat-containing 5

decreases expression
increases expression
multiple interactions

ISO

Folic Acid deficiency results in decreased expression of BIRC5 protein
Folic Acid results in increased expression of BIRC5 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BIRC5 mRNA
[Folic Acid co-treated with Camptothecin] results in decreased expression of BIRC5 mRNA; [Folic Acid co-treated with Doxorubicin] results in decreased expression of BIRC5 mRNA; [Folic Acid co-treated with Methyl Methanesulfonate] results in decreased expression of BIRC5 mRNA

PMID:22206623 PMID:28639913 PMID:30581319 PMID:36354958

NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155

G

B-cell linker

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BLNK mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BLNK mRNA

PMID:20938992 PMID:22206623

NCBI chr 1:249,703,064...249,770,533
Ensembl chr 1:249,703,072...249,770,533

G

biogenesis of lysosomal organelles complex 1 subunit 4

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of CNO mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BLOC1S4 mRNA

PMID:22206623 PMID:25629700

NCBI chr14:78,267,735...78,269,035
Ensembl chr14:78,267,508...78,269,564

G

biogenesis of lysosomal organelles complex 1 subunit 5

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BLOC1S5 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BLOC1S5 gene

PMID:20938992 PMID:22206623

NCBI chr17:26,377,549...26,402,869
Ensembl chr17:26,377,560...26,402,865

G

biogenesis of lysosomal organelles complex 1 subunit 6

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of BLOC1S6 mRNA

NCBI chr 3:130,269,979...130,280,109
Ensembl chr 3:130,268,442...130,281,360

G

bridge-like lipid transfer protein family member 3A

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BLTP3A gene

NCBI chr20:5,912,033...5,956,404
Ensembl chr20:5,912,106...5,956,403

G

biliverdin reductase A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BLVRA mRNA

NCBI chr 3:134,793,397...134,819,367
Ensembl chr 3:134,794,203...134,819,785

G

basic helix-loop-helix ARNT like 1

multiple interactions

ISO

[Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of BMAL1 mRNA; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of BMAL1 mRNA]

PMID:22206623 PMID:29127188

NCBI chr 1:176,766,222...176,864,741
Ensembl chr 1:176,829,305...176,864,739

G

BMI1 proto-oncogene, polycomb ring finger

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of BMI1 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of BMI1 mRNA

PMID:22206623 PMID:25629700

NCBI chr17:86,240,683...86,250,044
Ensembl chr17:86,243,491...86,250,024

G

bone morphogenetic protein 2

decreases expression

ISO

Folic Acid results in decreased expression of BMP2 mRNA

NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:141,264,646...141,274,760

G

BMP-2 inducible kinase

decreases expression

ISO

Folic Acid results in decreased expression of BMP2K mRNA

NCBI chr14:12,785,169...12,882,676
Ensembl chr14:12,785,169...12,882,657

G

bone morphogenetic protein 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BMP3 mRNA

NCBI chr14:11,012,564...11,041,282
Ensembl chr14:11,016,620...11,041,282

G

bone morphogenetic protein 4

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of BMP4 gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of BMP4 mRNA]

PMID:20938992 PMID:22206623

NCBI chr15:22,098,191...22,113,145
Ensembl chr15:22,098,470...22,105,172

G

bone morphogenetic protein 6

decreases expression

ISO

Folic Acid results in decreased expression of BMP6 mRNA

NCBI chr17:26,523,704...26,785,558
Ensembl chr17:26,523,704...26,675,261

G

bone morphogenetic protein 7

increases expression

ISO

Folic Acid results in increased expression of BMP7 mRNA

NCBI chr 3:182,059,318...182,135,273
Ensembl chr 3:182,052,337...182,135,137

G

bone morphogenetic protein 8a

decreases expression

ISO

Folic Acid results in decreased expression of BMP8A mRNA

NCBI chr 5:140,874,942...140,902,881
Ensembl chr 5:140,874,503...140,902,881

G

BMP-binding endothelial regulator

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BMPER mRNA

NCBI chr 8:30,008,049...30,253,201
Ensembl chr 8:30,008,148...30,434,359

G

bone morphogenetic protein receptor type 1A

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of BMPR1A mRNA]

NCBI chr16:9,740,751...9,786,861
Ensembl chr16:9,742,875...9,786,861

G

bone morphogenetic protein receptor type 2

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BMPR2 gene
Folic Acid results in decreased expression of BMPR2 mRNA

PMID:20938992 PMID:25629700

NCBI chr 9:68,685,942...68,801,353
Ensembl chr 9:68,685,988...68,801,350

G

BMS1 ribosome biogenesis factor

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BMS1 gene

NCBI chr 4:153,230,471...153,267,437
Ensembl chr 4:153,230,471...153,267,429

G

basonuclin zinc finger protein 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BNC1 gene

NCBI chr 1:145,326,881...145,352,534
Ensembl chr 1:145,326,892...145,353,510

G

BCL2 interacting protein 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of BNIP1 gene
Folic Acid results in decreased expression of BNIP1 mRNA

PMID:20938992 PMID:25629700

NCBI chr10:16,891,317...16,903,561
Ensembl chr10:16,891,317...16,903,561

G

BCL2 interacting protein 3

affects expression

ISO

Folic Acid affects the expression of BNIP3 mRNA

NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:203,137,778...203,154,962

G

BCL2 interacting protein 3 like

affects expression
decreases expression

ISO

Folic Acid affects the expression of BNIP3L mRNA
Folic Acid results in decreased expression of BNIP3L mRNA

PMID:17320366 PMID:25629700

NCBI chr15:45,350,081...45,373,213
Ensembl chr15:45,334,537...45,373,282

G

BOC cell adhesion associated, oncogene regulated

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BOC mRNA
Folic Acid results in decreased expression of BOC mRNA

PMID:20938992 PMID:25629700

NCBI chr11:69,628,703...69,704,009
Ensembl chr11:69,628,660...69,704,004

G

biorientation of chromosomes in cell division 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BOD1 mRNA

NCBI chr10:16,497,918...16,504,259
Ensembl chr10:16,497,876...16,504,253

G

BCL2 family apoptosis regulator BOK

decreases expression
increases expression

ISO

Folic Acid results in decreased expression of BOK mRNA
Folic Acid results in increased expression of BOK mRNA

PMID:21867686 PMID:25629700

NCBI chr 9:101,670,729...101,681,834
Ensembl chr 9:101,670,625...101,681,833

G

bolA family member 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BOLA3 mRNA

NCBI chr 4:117,411,044...117,420,491
Ensembl chr 4:117,410,680...117,420,491

G

BOP1 ribosomal biogenesis factor

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BOP1 mRNA

NCBI chr 7:110,052,716...110,076,529
Ensembl chr 7:110,052,720...110,076,529

G

BLOC-1 related complex subunit 6

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BORCS6 mRNA

NCBI chr10:54,259,349...54,261,203
Ensembl chr10:54,256,949...54,261,387

G

bisphosphoglycerate mutase

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of BPGM mRNA]

NCBI chr 4:64,106,809...64,135,749
Ensembl chr 4:64,106,804...64,135,627

G

biphenyl hydrolase like

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BPHL mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of BPHL gene

PMID:20938992 PMID:22206623

NCBI chr17:31,006,283...31,042,631
Ensembl chr17:31,004,972...31,042,632

G

3'(2'), 5'-bisphosphate nucleotidase 1

affects expression
decreases expression

EXP
ISO

Folic Acid affects the expression of BPNT1 protein
Folic Acid results in decreased expression of BPNT1 mRNA

PMID:16251605 PMID:25629700

NCBI chr13:99,397,127...99,425,056
Ensembl chr13:99,400,115...99,425,053

G

3'(2'), 5'-bisphosphate nucleotidase 2

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BPNT2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BPNT2 mRNA
Folic Acid results in decreased expression of IMPAD1 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr 5:22,573,241...22,600,126
Ensembl chr 5:22,570,165...22,600,126

G

bromodomain PHD finger transcription factor

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of BPTF mRNA]

NCBI chr10:92,480,007...92,582,485
Ensembl chr10:92,480,007...92,582,413

G

B-Raf proto-oncogene, serine/threonine kinase

decreases expression

ISO

Folic Acid results in decreased expression of BRAF mRNA

NCBI chr 4:69,329,772...69,476,931
Ensembl chr 4:69,342,813...69,476,931

G

BRCA1, DNA repair associated

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BRCA1 mRNA
[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of BRCA1 mRNA

PMID:20938992 PMID:24657277

NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,917,693...86,977,763

G

BRCA2, DNA repair associated

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BRCA2 gene
Folic Acid results in decreased expression of BRCA2 mRNA

PMID:20938992 PMID:21867686

NCBI chr12:4,895,092...4,939,340
Ensembl chr12:4,895,447...4,936,194

G

BRCA1/BRCA2-containing complex subunit 3

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of BRCC3 mRNA]

NCBI chr 9:2,073,927...2,076,469
Ensembl chr 9:2,073,184...2,084,185

G

bromodomain containing 2

increases expression

ISO

Folic Acid results in increased expression of BRD2 mRNA

NCBI chr20:4,728,282...4,737,286
Ensembl chr20:4,728,951...4,737,290

G

bromodomain containing 3

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BRD3 gene
Folic Acid results in increased expression of BRD3 mRNA

PMID:20938992 PMID:25629700

NCBI chr 3:31,173,332...31,227,749
Ensembl chr 3:31,173,332...31,227,629

G

bromodomain containing 4

decreases expression

ISO

Folic Acid results in decreased expression of BRD4 mRNA

NCBI chr 7:11,866,997...11,946,575
Ensembl chr 7:11,866,997...11,946,923

G

bromodomain containing 7

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BRD7 gene

NCBI chr19:34,882,238...34,910,944
Ensembl chr19:34,882,304...34,910,944

G

bromodomain containing 8

decreases expression

ISO

Folic Acid results in decreased expression of BRD8 mRNA

NCBI chr18:26,455,824...26,504,106
Ensembl chr18:26,455,512...26,504,006

G

bromodomain testis associated

decreases expression

ISO

Folic Acid results in decreased expression of BRDT mRNA

NCBI chr14:2,532,275...2,590,780
Ensembl chr14:2,532,275...2,590,760

G

brain protein I3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BRI3 mRNA

NCBI chr12:15,454,673...15,478,319
Ensembl chr12:15,454,673...15,478,319

G

biogenesis of ribosomes BRX1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BRIX1 mRNA

NCBI chr 2:61,177,769...61,188,647
Ensembl chr 2:61,177,771...61,188,647

G

BRICK1 subunit of SCAR/WAVE actin nucleating complex

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BRK1 mRNA

NCBI chr 4:148,306,436...148,321,668
Ensembl chr 4:148,306,398...148,321,984

G

BRMS1, transcriptional repressor and anoikis regulator

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of BRMS1 gene

NCBI chr 1:211,775,142...211,784,411
Ensembl chr 1:211,775,095...211,784,410

G

BRMS1 like transcriptional repressor

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of BRMS1L mRNA

NCBI chr 6:79,001,803...79,035,735
Ensembl chr 6:79,000,615...79,035,734

G

bromodomain and PHD finger containing, 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of BRPF3 mRNA

NCBI chr20:6,866,378...6,904,456
Ensembl chr20:6,867,635...6,904,456

G

BR serine/threonine kinase 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of BRSK2 gene

NCBI chr 1:206,465,040...206,518,156
Ensembl chr 1:206,465,040...206,518,156

G

bromodomain and WD repeat domain containing 1

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of BRWD1 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BRWD1 mRNA

PMID:21867686 PMID:22206623 PMID:25629700

NCBI chr11:48,756,174...48,853,692
Ensembl chr11:48,756,811...48,848,256

G

BSD domain containing 1

decreases expression

ISO

Folic Acid results in decreased expression of BSDC1 mRNA

NCBI chr 5:147,083,044...147,113,997
Ensembl chr 5:147,079,838...147,114,241

G

basigin

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of BSG mRNA]

NCBI chr 7:10,643,788...10,651,005
Ensembl chr 7:10,643,789...10,651,005

G

bassoon (presynaptic cytomatrix protein)

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of BSN mRNA

NCBI chr 8:117,663,447...117,754,412
Ensembl chr 8:117,670,334...117,754,412

G

B-box and SPRY domain containing

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BSPRY mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BSPRY mRNA

PMID:20938992 PMID:22206623

NCBI chr 5:80,942,974...80,965,157
Ensembl chr 5:80,942,979...80,988,154

G

bone marrow stromal cell antigen 2

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of BST2 mRNA]

NCBI chr16:18,250,593...18,254,967
Ensembl chr16:18,251,847...18,254,967

G

BTB domain containing 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BTBD1 mRNA

NCBI chr 1:145,143,806...145,183,653
Ensembl chr 1:145,143,808...145,181,197

G

BTB domain containing 10

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of BTBD10 mRNA

NCBI chr 1:176,865,817...176,923,663
Ensembl chr 1:176,865,817...176,923,663

G

BTB domain containing 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BTBD2 mRNA

NCBI chr 7:9,710,392...9,726,032
Ensembl chr 7:9,712,269...9,726,032

G

BTB domain containing 6

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BTBD6 mRNA

NCBI chr 6:137,879,202...137,881,662
Ensembl chr 6:137,879,162...137,881,652

G

BTB domain containing 8

decreases expression

ISO

Folic Acid results in decreased expression of BTBD8 mRNA

NCBI chr14:2,410,093...2,483,114
Ensembl chr14:2,410,093...2,479,202

G

BTB domain containing 9

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BTBD9 mRNA

NCBI chr20:8,287,813...8,645,437
Ensembl chr20:8,290,456...8,641,292

G

biotinidase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BTD mRNA

NCBI chr16:6,869,448...6,900,711
Ensembl chr16:6,869,291...6,901,410

G

basic transcription factor 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BTF3 mRNA

NCBI chr 2:31,394,010...31,401,138
Ensembl chr 2:31,394,011...31,401,125
Ensembl chr13:31,394,011...31,401,125

G

basic transcription factor 3-like 4

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BTF3L4 mRNA
Folic Acid results in decreased expression of BTF3L4 mRNA

PMID:22206623 PMID:25629700

NCBI chr 5:128,796,594...128,816,219
Ensembl chr 5:128,796,594...128,816,602

G

BTG anti-proliferation factor 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BTG1 mRNA

NCBI chr 7:33,228,149...33,230,406
Ensembl chr 7:33,227,833...33,230,406

G

BTG anti-proliferation factor 2

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of BTG2 gene
Folic Acid results in decreased expression of BTG2 mRNA

PMID:20938992 PMID:25629700

NCBI chr13:48,083,931...48,087,690
Ensembl chr13:48,083,931...48,087,690

G

BTG anti-proliferation factor 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BTG3 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BTG3 mRNA

PMID:20938992 PMID:22206623

NCBI chr11:30,517,068...30,532,981
Ensembl chr11:30,517,072...30,533,082

G

Bruton tyrosine kinase

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BTK mRNA

NCBI chr X:102,016,070...102,055,448
Ensembl chr X:102,016,074...102,055,143

G

butyrophilin, subfamily 1, member A1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of BTN1A1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of BTN1A1 gene

PMID:20938992 PMID:22206623

NCBI chr17:42,080,217...42,092,286
Ensembl chr17:42,081,527...42,092,276

G

butyrophilin-like 2

decreases expression

ISO

Folic Acid results in decreased expression of BTNL2 mRNA

NCBI chr20:4,492,100...4,505,932
Ensembl chr20:4,492,111...4,505,932

G

BUB1 mitotic checkpoint serine/threonine kinase

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BUB1 mRNA
[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of BUB1 mRNA

PMID:20938992 PMID:24657277

NCBI chr 3:135,473,525...135,504,921
Ensembl chr 3:135,472,582...135,504,921

G

BUB1 mitotic checkpoint serine/threonine kinase B

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BUB1B mRNA
[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of BUB1B mRNA

PMID:20938992 PMID:24657277

NCBI chr 3:126,017,019...126,069,470
Ensembl chr 3:126,017,045...126,069,796

G

BUD31 homolog

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of BUD31 mRNA
Folic Acid results in decreased expression of BUD31 mRNA

PMID:22206623 PMID:25629700

NCBI chr12:14,576,602...14,584,132
Ensembl chr12:14,576,605...14,584,039

G

basic leucine zipper and W2 domains 1

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BZW1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BZW1 gene
Folic Acid results in decreased expression of BZW1 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr 9:67,424,860...67,438,656
Ensembl chr 9:67,424,866...67,439,684

G

basic leucine zipper and W2 domains 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BZW2 mRNA; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of BZW2 mRNA]

PMID:20938992 PMID:22206623

NCBI chr 6:58,555,362...58,615,921
Ensembl chr 6:58,554,961...58,615,912

G

similar to human chromosome 5 open reading frame 58

decreases expression

ISO

Folic Acid results in decreased expression of C5ORF58 mRNA

NCBI chr10:19,195,306...19,203,013
Ensembl chr10:19,193,035...19,205,380

G

similar to human chromosome 1 open reading frame 115

decreases expression

ISO

Folic Acid results in decreased expression of C1ORF115 mRNA

NCBI chr13:98,953,841...98,963,577
Ensembl chr13:98,953,843...98,963,810

G

similar to human chromosome 1 open reading frame 226

decreases expression

ISO

Folic Acid results in decreased expression of C1ORF226 mRNA

NCBI chr13:85,063,350...85,071,435
Ensembl chr13:85,063,350...85,353,741

G

similar to human chromosome 19 open reading frame 53

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of D8ERTD738E mRNA

NCBI chr19:40,819,830...40,822,609

G

C1GALT1-specific chaperone 1

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of C1GALT1C1 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of C1GALT1C1 mRNA

PMID:22206623 PMID:25629700

NCBI chr X:122,243,736...122,248,217
Ensembl chr X:122,234,454...122,248,422

G

similar to human chromosome 11 open reading frame 86

decreases expression

ISO

Folic Acid results in decreased expression of C11ORF86 mRNA

NCBI chr 1:211,213,429...211,225,624
Ensembl chr 1:211,213,445...211,229,116

G

similar to human chromosome 15 open reading frame 40

decreases expression

ISO

Folic Acid results in decreased expression of C15ORF40 mRNA

NCBI chr 1:145,135,088...145,144,826
Ensembl chr 1:145,126,868...145,141,356

G

similar to human chromosome 9 open reading frame 85

decreases expression

ISO

Folic Acid results in decreased expression of C9ORF85 mRNA

NCBI chr 1:228,562,621...228,624,472
Ensembl chr 1:228,564,731...228,624,278

G

complement C1q A chain

decreases expression

ISO

Folic Acid results in decreased expression of C1QA mRNA

NCBI chr 5:154,417,086...154,419,933
Ensembl chr 5:154,417,087...154,427,732

G

complement C1q B chain

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of C1QB mRNA; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of C1QB mRNA]

PMID:20938992 PMID:22206623

NCBI chr 5:154,402,276...154,407,827
Ensembl chr 5:154,402,279...154,407,840

G

complement C1q binding protein

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of C1QBP mRNA

NCBI chr10:56,198,534...56,203,185
Ensembl chr10:56,198,540...56,203,235

G

C1q and TNF related 1

decreases expression

ISO

Folic Acid results in decreased expression of C1QTNF1 mRNA

NCBI chr10:104,159,021...104,180,253
Ensembl chr10:104,158,886...104,180,251

G

C1q and TNF related 12

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of C1QTNF12 mRNA

NCBI chr 5:171,833,854...171,838,229
Ensembl chr 5:171,833,854...171,838,800

G

C1q and TNF related 2

decreases expression

ISO

Folic Acid results in decreased expression of C1QTNF2 mRNA

NCBI chr10:28,443,326...28,460,400
Ensembl chr10:28,443,425...28,460,395

G

C1q and TNF related 3

increases expression

ISO

Folic Acid results in increased expression of C1QTNF3 mRNA

NCBI chr 2:61,644,225...61,666,640
Ensembl chr 2:61,644,276...61,666,559

G

C1q and TNF related 4

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of C1QTNF4 mRNA

NCBI chr 3:97,310,220...97,328,818
Ensembl chr 3:97,327,670...97,342,587

G

C1q and TNF related 6

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of C1QTNF6 mRNA

NCBI chr 7:111,958,348...111,964,948
Ensembl chr 7:111,958,350...111,966,871

G

C1q and TNF related 7

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of C1QTNF7 mRNA
Folic Acid results in decreased expression of C1QTNF7 mRNA

PMID:20938992 PMID:21867686

NCBI chr14:71,680,415...71,792,931
Ensembl chr14:71,680,479...71,792,865

G

complement C1r

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of C1R mRNA

NCBI chr 4:159,099,013...159,109,770
Ensembl chr 4:159,098,918...159,109,714

G

complement C1r subcomponent like

decreases expression

ISO

Folic Acid results in decreased expression of C1RL mRNA

NCBI chr 4:159,080,495...159,097,066
Ensembl chr 4:159,080,495...159,097,066

G

complement C1s

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of C1S1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of C1S mRNA

PMID:20938992 PMID:22206623

NCBI chr 4:159,116,549...159,128,736
Ensembl chr 4:159,116,549...159,128,736

G

C2CD2-like

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of C2CD2L mRNA

NCBI chr 8:53,544,887...53,557,127
Ensembl chr 8:53,544,892...53,555,153

G

C2 domain containing 3 centriole elongation regulator

decreases expression

ISO

Folic Acid results in decreased expression of C2CD3 mRNA

NCBI chr 1:164,127,304...164,225,088
Ensembl chr 1:164,127,281...164,225,086

G

C2 calcium-dependent domain containing 4B

decreases expression

ISO

Folic Acid results in decreased expression of C2CD4B mRNA

NCBI chr 8:77,254,327...77,277,620
Ensembl chr 8:77,238,551...77,279,879

G

C2 calcium dependent domain containing 6

increases expression

ISO

Folic Acid results in increased expression of C2CD6 mRNA

NCBI chr 9:67,929,069...68,024,993
Ensembl chr 9:67,929,082...68,024,960

G

complement C3

multiple interactions
increases expression

ISO

[Folic Acid affects the susceptibility to Pemetrexed] which affects the expression of C3 mRNA; [Folic Acid affects the susceptibility to Pemetrexed] which affects the expression of C3 protein; [Folic Acid deficiency co-treated with Methotrexate] results in increased expression of C3 mRNA
Folic Acid results in increased expression of C3 protein
Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of C3 mRNA]; icariin inhibits the reaction [Folic Acid results in increased expression of C3 protein]
Folic Acid deficiency results in increased expression of C3 mRNA; Folic Acid deficiency results in increased expression of C3 protein

PMID:22206623 PMID:22975265 PMID:24657277 PMID:38272249

NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,174,412...2,201,339

G

complement C3a receptor 1

multiple interactions
decreases expression
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of C3AR1 mRNA
Folic Acid results in decreased expression of C3AR1 mRNA
Folic Acid results in increased expression of C3AR1 mRNA

PMID:20938992 PMID:21867686 PMID:25629700

NCBI chr 4:157,747,419...157,756,609
Ensembl chr 4:157,746,089...157,776,323

G

complement C4B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of C4B mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of C4B mRNA

PMID:20938992 PMID:22206623

NCBI chr20:4,201,979...4,216,292
Ensembl chr20:4,201,961...4,216,289

G

complement C7

decreases expression
increases expression

ISO

Folic Acid results in decreased expression of C7 mRNA
Folic Acid results in increased expression of C7 mRNA

PMID:21867686 PMID:25629700

NCBI chr 2:55,815,687...55,892,605
Ensembl chr 2:55,816,807...55,892,672

G

complement C8 gamma chain

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of C8G mRNA]

NCBI chr 3:28,718,648...28,720,232

G

carbonic anhydrase 13

decreases expression

ISO

Folic Acid results in decreased expression of CA13 mRNA

NCBI chr 2:88,649,643...88,680,763
Ensembl chr 2:88,649,625...88,680,763

G

carbonic anhydrase 14

decreases expression

ISO

Folic Acid results in decreased expression of CAR14 mRNA

NCBI chr 2:186,131,196...186,138,164
Ensembl chr 2:186,129,341...186,138,863

G

carbonic anhydrase 4

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CAR4 mRNA

NCBI chr10:70,325,102...70,333,916
Ensembl chr10:70,325,358...70,333,916

G

carbonic anhydrase 5B

decreases expression

ISO

Folic Acid results in decreased expression of CA5B mRNA

NCBI chr X:34,106,553...34,166,651
Ensembl chr X:34,067,403...34,166,653

G

carbonic anhydrase 8

decreases expression

ISO

Folic Acid results in decreased expression of CAR8 mRNA

NCBI chr 5:26,102,767...26,199,819
Ensembl chr 5:26,102,813...26,199,796

G

calcineurin binding protein 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CABIN1 gene
Folic Acid results in decreased expression of CABIN1 mRNA

PMID:20938992 PMID:25629700

NCBI chr20:12,892,750...13,014,801
Ensembl chr20:12,892,771...13,014,800

G

Cdk5 and Abl enzyme substrate 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CABLES1 mRNA

NCBI chr18:3,349,681...3,455,956
Ensembl chr18:3,351,652...3,455,956

G

Cdk5 and Abl enzyme substrate 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CABLES2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CABLES2 mRNA

PMID:20938992 PMID:22206623

NCBI chr 3:187,725,128...187,739,880
Ensembl chr 3:187,725,031...187,740,027

G

calcium channel flower domain containing 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CACFD1 mRNA

NCBI chr 3:30,733,958...30,750,237
Ensembl chr 3:30,736,637...30,744,764

G

cache domain containing 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CACHD1 mRNA

NCBI chr 5:120,527,224...120,752,685
Ensembl chr 5:120,526,770...120,772,877

G

calcium voltage-gated channel subunit alpha1 A

multiple interactions
decreases expression
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CACNA1A gene
Folic Acid results in decreased expression of CACNA1A mRNA
Folic Acid results in increased expression of CACNA1A mRNA

PMID:20938992 PMID:25006883 PMID:25629700

NCBI chr19:40,425,560...40,724,810
Ensembl chr19:40,425,560...40,724,599

G

calcium voltage-gated channel subunit alpha1 B

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CACNA1B gene
Folic Acid results in increased expression of CACNA1B mRNA

PMID:20938992 PMID:25006883

NCBI chr 3:27,779,133...27,944,292
Ensembl chr 3:27,779,166...27,944,285

G

calcium voltage-gated channel subunit alpha1 D

decreases expression

ISO

Folic Acid results in decreased expression of CACNA1D mRNA

NCBI chr16:5,233,682...5,527,549
Ensembl chr16:5,233,690...5,674,692

G

calcium voltage-gated channel subunit alpha1 G

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CACNA1G gene

NCBI chr10:79,851,886...79,919,926
Ensembl chr10:79,851,896...79,919,634

G

calcium voltage-gated channel subunit alpha1 I

decreases expression

ISO

Folic Acid results in decreased expression of CACNA1I mRNA

NCBI chr 7:113,716,266...113,827,670
Ensembl chr 7:113,716,266...113,827,670

G

calcium voltage-gated channel auxiliary subunit alpha2delta 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CACNA2D1 mRNA
Folic Acid results in decreased expression of CACNA2D1 mRNA

PMID:20938992 PMID:25629700

NCBI chr 4:19,902,324...20,330,287
Ensembl chr 4:19,905,764...20,330,147

G

calcium voltage-gated channel auxiliary subunit alpha2delta 2

decreases expression

ISO

Folic Acid results in decreased expression of CACNA2D2 mRNA

NCBI chr 8:116,950,860...117,082,159
Ensembl chr 8:116,950,907...117,081,759

G

calcium voltage-gated channel auxiliary subunit beta 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CACNB2 gene

NCBI chr17:82,473,097...82,818,564
Ensembl chr17:82,473,129...82,818,564

G

calcium voltage-gated channel auxiliary subunit beta 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CACNB3 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CACNB3 mRNA

PMID:20938992 PMID:22206623

NCBI chr 7:131,663,810...131,676,085
Ensembl chr 7:131,662,545...131,676,085

G

calcium voltage-gated channel auxiliary subunit gamma 2

decreases expression

ISO

Folic Acid results in decreased expression of CACNG2 mRNA

NCBI chr 7:111,451,605...111,579,071
Ensembl chr 7:111,455,006...111,577,757

G

calcium voltage-gated channel auxiliary subunit gamma 5

decreases expression

ISO

Folic Acid results in decreased expression of CACNG5 mRNA

NCBI chr10:93,327,142...93,369,244
Ensembl chr10:93,327,150...93,336,667

G

calcium voltage-gated channel auxiliary subunit gamma 6

decreases expression

ISO

Folic Acid results in decreased expression of CACNG6 mRNA

NCBI chr 1:74,648,342...74,663,351
Ensembl chr 1:74,648,063...74,662,753

G

calcium voltage-gated channel auxiliary subunit gamma 7

multiple interactions
increases expression

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CACNG7 mRNA]
Folic Acid results in increased expression of CACNG7 mRNA

PMID:22206623 PMID:25629700

NCBI chr 1:74,715,483...74,746,669
Ensembl chr 1:74,715,483...74,746,669

G

calcyclin binding protein

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CACYBP mRNA

NCBI chr13:74,970,917...74,981,298
Ensembl chr13:74,970,923...74,981,505

G

cell adhesion molecule 1

increases expression
multiple interactions

ISO

Folic Acid results in increased expression of CADM1 mRNA; Folic Acid results in increased expression of CADM1 protein
CADM1 protein affects the reaction [Folic Acid results in increased expression of CDH1 protein]; FOLR1 protein affects the reaction [Folic Acid results in increased expression of CADM1 mRNA]; FOLR1 protein affects the reaction [Folic Acid results in increased expression of CADM1 protein]; U 0126 inhibits the reaction [Folic Acid results in increased expression of CADM1 mRNA]; U 0126 inhibits the reaction [Folic Acid results in increased expression of CADM1 protein]

NCBI chr 8:56,744,374...57,075,264
Ensembl chr 8:56,744,372...57,080,192

G

cell adhesion molecule 2

decreases expression

ISO

Folic Acid results in decreased expression of CADM2 mRNA

NCBI chr11:17,994,856...18,971,895
Ensembl chr11:17,994,856...18,971,448

G

cell adhesion molecule 4

increases expression

ISO

Folic Acid results in increased expression of CADM4 mRNA

NCBI chr 1:89,203,089...89,225,345
Ensembl chr 1:89,202,554...89,225,345

G

calcium dependent secretion activator

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CADPS mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CADPS gene

PMID:20938992 PMID:22206623

NCBI chr15:14,719,078...15,173,218
Ensembl chr15:14,720,726...15,173,211

G

calcium dependent secretion activator 2

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CADPS2 gene
Folic Acid results in decreased expression of CADPS2 mRNA

PMID:20938992 PMID:25629700

NCBI chr 4:52,746,054...53,275,252
Ensembl chr 4:52,746,065...53,275,004

G

calbindin 1

multiple interactions

ISO

Folic Acid inhibits the reaction [sodium arsenite results in decreased expression of CALB1 protein]

NCBI chr 5:34,172,612...34,199,555
Ensembl chr 5:34,172,664...34,200,160

G

calcitonin-related polypeptide alpha

increases expression
decreases expression

ISO

Folic Acid results in increased expression of CALCA mRNA
Folic Acid results in decreased expression of CALCA mRNA

PMID:21867686 PMID:25629700

NCBI chr 1:178,312,636...178,317,588
Ensembl chr 1:178,312,638...178,317,529

G

calcium binding and coiled coil domain 1

decreases expression

ISO

Folic Acid results in decreased expression of CALCOCO1 mRNA

NCBI chr 7:135,713,208...135,728,044
Ensembl chr 7:135,713,208...135,727,928

G

calmodulin 1

affects expression
decreases expression
multiple interactions

ISO

Folic Acid affects the expression of CALM1 mRNA
Folic Acid results in decreased expression of CALM1 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CALM1 mRNA

PMID:21867686 PMID:22206623 PMID:25629700

NCBI chr 6:125,217,191...125,227,855
Ensembl chr 6:125,217,246...125,225,381

G

calmodulin 2

decreases expression

ISO

Folic Acid results in decreased expression of CALM2 mRNA

NCBI chr 6:12,845,170...12,857,830
Ensembl chr15:64,519,554...64,520,657
Ensembl chr 6:64,519,554...64,520,657

G

calmodulin 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CALM3 mRNA

NCBI chr 1:86,718,761...86,725,869
Ensembl chr 1:86,717,321...86,725,960

G

calmodulin-like 4

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CALML4 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CALML4 mRNA

PMID:20938992 PMID:22206623

NCBI chr 8:72,218,870...72,230,650
Ensembl chr 8:72,218,613...72,230,650

G

calneuron 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CALN1 gene

NCBI chr12:31,447,964...31,939,847

G

calreticulin

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CALR mRNA; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CALR mRNA]

PMID:20938992 PMID:22206623

NCBI chr19:40,213,367...40,218,262
Ensembl chr19:40,213,239...40,219,236

G

calumenin

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CALU mRNA

NCBI chr 4:58,914,456...58,941,957
Ensembl chr 4:58,914,421...58,941,956

G

calcyon neuron-specific vesicular protein

multiple interactions
affects expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CALY gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CALY mRNA]
Folic Acid affects the expression of CALY mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr 1:204,292,317...204,303,506
Ensembl chr 1:204,292,318...204,303,196

G

calcium/calmodulin-dependent protein kinase ID

increases expression

ISO

Folic Acid results in increased expression of CAMK1D mRNA

NCBI chr17:77,491,191...77,892,018
Ensembl chr17:77,491,220...77,892,012

G

calcium/calmodulin-dependent protein kinase II beta

decreases expression

ISO

Folic Acid results in decreased expression of CAMK2B mRNA

NCBI chr14:85,059,166...85,148,121
Ensembl chr14:85,059,191...85,148,485

G

calcium/calmodulin-dependent protein kinase II delta

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CAMK2D mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CAMK2D mRNA

PMID:20938992 PMID:22206623

NCBI chr 2:217,698,324...217,961,898
Ensembl chr 2:217,698,551...217,960,276

G

calcium/calmodulin-dependent protein kinase II gamma

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CAMK2G mRNA

NCBI chr15:3,553,238...3,612,310
Ensembl chr15:3,553,294...3,612,310

G

calcium/calmodulin-dependent protein kinase II inhibitor 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CAMK2N1 gene
Folic Acid results in decreased expression of CAMK2N1 mRNA

PMID:20938992 PMID:25629700

NCBI chr 5:155,958,116...155,959,897
Ensembl chr 5:155,957,878...155,961,058

G

calcium/calmodulin-dependent protein kinase IV

decreases expression

ISO

Folic Acid results in decreased expression of CAMK4 mRNA

NCBI chr18:24,857,152...25,076,054
Ensembl chr18:24,857,146...25,077,193

G

calcium/calmodulin-dependent protein kinase kinase 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of CAMKK1; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CAMKK1 gene; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CAMKK1 mRNA
Folic Acid results in decreased expression of CAMKK1 mRNA

PMID:20938992 PMID:21867686

NCBI chr10:58,135,872...58,159,023
Ensembl chr10:58,135,915...58,159,010

G

CaM kinase-like vesicle-associated

increases expression

ISO

Folic Acid results in increased expression of CAMKV mRNA

NCBI chr 8:117,505,439...117,519,785
Ensembl chr 8:117,505,408...117,519,797

G

calcium modulating ligand

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CAML mRNA

NCBI chr17:8,997,868...9,009,140
Ensembl chr17:8,997,272...9,009,012

G

calmodulin regulated spectrin-associated protein 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CAMSAP1 gene

NCBI chr 3:29,144,318...29,206,382
Ensembl chr 3:29,144,318...29,204,184

G

calmodulin regulated spectrin-associated protein family, member 2

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CAMSAP2 gene
Folic Acid results in decreased expression of CAMSAP2 mRNA

PMID:20938992 PMID:25629700

NCBI chr13:50,274,950...50,354,298
Ensembl chr13:50,274,950...50,354,298

G

calmodulin binding transcription activator 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CAMTA1 gene
Folic Acid results in decreased expression of CAMTA1 mRNA

PMID:20938992 PMID:25629700

NCBI chr 5:166,791,639...167,639,502
Ensembl chr 5:166,793,101...167,639,733

G

cullin-associated and neddylation-dissociated 1

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CAND1 mRNA]

NCBI chr 7:56,566,765...56,604,653
Ensembl chr 7:56,551,394...56,604,655

G

cullin-associated and neddylation-dissociated 2 (putative)

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CAND2 mRNA
Folic Acid results in decreased expression of CAND2 mRNA

PMID:20938992 PMID:25629700

NCBI chr 4:150,507,659...150,535,755
Ensembl chr 4:150,507,657...150,541,293

G

calcium activated nucleotidase 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CANT1 gene

NCBI chr10:104,135,676...104,148,854
Ensembl chr10:104,135,682...104,148,698

G

cyclase associated actin cytoskeleton regulatory protein 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CAP1 mRNA

NCBI chr 5:140,427,265...140,507,678
Ensembl chr 5:140,427,269...140,453,470

G

cyclase associated actin cytoskeleton regulatory protein 2

decreases expression

ISO

Folic Acid results in decreased expression of CAP2 mRNA

NCBI chr17:18,260,462...18,409,681
Ensembl chr17:18,261,646...18,409,563

G

capping actin protein, gelsolin like

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CAPG mRNA

NCBI chr 4:106,152,912...106,170,010
Ensembl chr 4:106,152,890...106,170,672

G

calpain 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CAPN1 mRNA

NCBI chr 1:212,705,219...212,736,134
Ensembl chr 1:212,705,222...212,729,445

G

calpain 10

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CAPN10 mRNA

NCBI chr 9:100,943,665...100,957,910
Ensembl chr 9:100,945,551...100,957,912

G

calpain 15

increases expression

ISO

Folic Acid results in increased expression of CAPN15 mRNA

NCBI chr10:15,477,311...15,503,913
Ensembl chr10:15,477,313...15,503,913

G

calpain 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CAPN2 mRNA

NCBI chr13:96,681,902...96,732,625
Ensembl chr13:96,681,848...96,732,625

G

calpain 5

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CAPN5 mRNA

NCBI chr 1:161,827,474...161,884,142
Ensembl chr 1:161,827,474...161,884,142

G

calpain 6

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CAPN6 mRNA

NCBI chr X:112,177,467...112,202,178
Ensembl chr X:112,177,467...112,202,178

G

calpain 7

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of CAPN7 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CAPN7 mRNA

PMID:22206623 PMID:25629700

NCBI chr16:6,552,048...6,588,317
Ensembl chr16:6,552,049...6,588,316

G

calpain 9

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CAPN9 mRNA

NCBI chr19:69,446,847...69,483,810
Ensembl chr19:69,446,847...69,483,810

G

calpain, small subunit 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CAPNS1 mRNA

NCBI chr 1:94,572,083...94,582,332
Ensembl chr 1:94,572,083...94,583,368

G

cell cycle associated protein 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CAPRIN1 mRNA

NCBI chr 3:110,606,489...110,685,408
Ensembl chr 3:110,606,489...110,685,562

G

caprin family member 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CAPRIN2 mRNA

NCBI chr 4:183,537,935...183,592,162
Ensembl chr 4:183,537,430...183,592,809

G

calcyphosine-like

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CAPSL mRNA

NCBI chr 2:60,122,162...60,152,692
Ensembl chr 2:60,138,589...60,152,838

G

capping actin protein of muscle Z-line subunit alpha 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CAPZA1 mRNA

NCBI chr 2:195,008,035...195,053,100
Ensembl chr 2:195,008,039...195,053,100

G

capping actin protein of muscle Z-line subunit alpha 2

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of CAPZA2 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CAPZA2 mRNA

PMID:22206623 PMID:25629700

NCBI chr 4:46,944,040...46,979,930
Ensembl chr 4:46,895,701...46,979,938

G

capping actin protein of muscle Z-line subunit beta

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CAPZB gene

NCBI chr 5:156,718,619...156,818,623
Ensembl chr 5:156,650,432...156,818,619

G

carbonic anhydrase 10

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CAR10 gene

NCBI chr10:78,551,067...79,053,421
Ensembl chr10:78,551,067...79,053,421

G

carbonic anhydrase 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CAR2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CAR2 mRNA

PMID:20938992 PMID:22206623

NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064

G

caspase recruitment domain family, member 10

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CARD10 gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CARD10 mRNA]

PMID:20938992 PMID:22206623

NCBI chr 7:112,210,944...112,252,044
Ensembl chr 7:112,210,776...112,239,806

G

calcium regulated heat stable protein 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CARHSP1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CARHSP1 mRNA

PMID:20938992 PMID:22206623

NCBI chr10:7,453,602...7,467,218
Ensembl chr10:7,452,978...7,467,770

G

carnosine N-methyltransferase 1

multiple interactions

ISO

Folic Acid inhibits the reaction [Doxorubicin results in decreased expression of CARNMT1 mRNA]

NCBI chr 1:225,520,345...225,549,971
Ensembl chr 1:225,520,151...225,550,232

G

cysteinyl-tRNA synthetase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CARS1 mRNA

NCBI chr 1:208,183,092...208,225,425
Ensembl chr 1:208,182,788...208,225,407

G

cysteinyl-tRNA synthetase 2, mitochondrial

decreases expression

ISO

Folic Acid results in decreased expression of CARS2 mRNA

NCBI chr16:84,649,617...84,689,254
Ensembl chr16:84,645,627...84,690,192

G

CAS1 domain containing 1

decreases expression

ISO

Folic Acid results in decreased expression of CASD1 mRNA

NCBI chr 4:33,613,805...33,705,821
Ensembl chr 4:33,613,450...33,705,821

G

calcium/calmodulin dependent serine protein kinase

decreases expression

ISO

Folic Acid results in decreased expression of CASK mRNA

NCBI chr X:11,572,328...11,915,831
Ensembl chr X:11,572,636...11,911,948

G

cask-interacting protein 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CASKIN2 mRNA

NCBI chr10:101,526,131...101,540,362
Ensembl chr10:101,526,195...101,540,349

G

caspase 1

affects response to substance
increases activity
multiple interactions

ISO

CASP1 protein affects the susceptibility to Folic Acid deficiency
Folic Acid deficiency results in increased activity of CASP1 protein
[Folic Acid deficiency results in increased abundance of Homocysteine] promotes the reaction [NLRC3 protein binds to PYCARD protein binds to CASP1 protein]; CASP1 protein affects the reaction [Folic Acid deficiency results in increased expression of IL1B protein]; PYCARD protein affects the reaction [Folic Acid deficiency results in increased activity of CASP1 protein]

NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275

G

caspase 12

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CASP12 mRNA; Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in increased expression of CASP12 protein modified form]

PMID:20938992 PMID:29068127

NCBI chr 8:10,927,188...10,954,442
Ensembl chr 8:10,926,994...10,954,442

G

caspase 14

decreases expression

ISO

Folic Acid results in decreased expression of CASP14 mRNA

NCBI chr 7:11,577,315...11,583,987
Ensembl chr 7:11,580,339...11,583,171

G

caspase 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CASP2 mRNA

NCBI chr 4:72,116,265...72,134,023
Ensembl chr 4:72,116,246...72,134,022

G

caspase 3

multiple interactions
increases activity
affects expression
increases cleavage
increases expression

ISO
EXP

6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride inhibits the reaction [Folic Acid results in increased activity of CASP3 protein]; 6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride promotes the reaction [pyrazolanthrone inhibits the reaction [Folic Acid results in increased activity of CASP3 protein]]; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CASP3 mRNA; Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in increased expression of CASP3 protein modified form]; Folic Acid inhibits the reaction [sodium arsenite results in increased cleavage of CASP3 protein]; Nicorandil inhibits the reaction [Folic Acid results in increased expression of CASP3 protein]; nilotinib inhibits the reaction [Folic Acid results in increased expression of CASP3 protein]; pyrazolanthrone inhibits the reaction [Folic Acid results in increased activity of CASP3 protein]; pyrazolanthrone promotes the reaction [6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride inhibits the reaction [Folic Acid results in increased activity of CASP3 protein]]; Trimetazidine inhibits the reaction [Folic Acid results in increased expression of CASP3 protein]
Folic Acid affects the expression of CASP3 protein
Folic Acid deficiency results in increased cleavage of CASP3 protein
Folic Acid affects the reaction [Homocysteine affects the cleavage of CASP3 protein]; Folic Acid affects the reaction [Homocysteine affects the expression of CASP3 mRNA]; Folic Acid inhibits the reaction [aluminum maltolate results in increased cleavage of CASP3 protein]; MIR19A mRNA affects the reaction [Folic Acid inhibits the reaction [aluminum maltolate results in increased cleavage of CASP3 protein]]; MIR19B1 mRNA affects the reaction [Folic Acid inhibits the reaction [aluminum maltolate results in increased cleavage of CASP3 protein]]
[Methionine co-treated with Betaine co-treated with Choline co-treated with Folic Acid] inhibits the reaction [Carbon Tetrachloride results in increased expression of CASP3 mRNA]; Folic Acid inhibits the reaction [Dietary Fats results in increased expression of CASP3 mRNA]; Folic Acid inhibits the reaction [Homocysteine results in increased expression of CASP3 protein]; Folic Acid inhibits the reaction [Methotrexate results in decreased expression of CASP3 protein]; Folic Acid inhibits the reaction [Vitamin B 12 promotes the reaction [Dietary Fats results in increased expression of CASP3 mRNA]]

PMID:20938992 PMID:21349824 PMID:23219837 PMID:23935743 PMID:27113042 More...

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732

G

caspase 4

affects expression
multiple interactions

ISO

Folic Acid affects the expression of CASP4 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CASP4 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CASP4 mRNA

PMID:16361273 PMID:20938992 PMID:22206623

NCBI chr 8:10,883,817...10,919,978
Ensembl chr 8:10,883,769...10,920,727

G

caspase 6

affects expression
multiple interactions

ISO

Folic Acid affects the expression of CASP6 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CASP6 mRNA

PMID:16361273 PMID:22206623

NCBI chr 2:221,140,287...221,152,727
Ensembl chr 2:221,140,256...221,152,726

G

caspase 7

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CASP7 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CASP7 gene
Folic Acid inhibits the reaction [Doxorubicin results in decreased expression of CASP7 mRNA]

PMID:20938992 PMID:30581319

NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512

G

caspase 8

affects expression
multiple interactions

ISO
EXP

Folic Acid affects the expression of CASP8 mRNA
Folic Acid affects the reaction [Homocysteine affects the expression of CASP8 mRNA]; Folic Acid affects the reaction [Homocysteine affects the expression of CASP8 protein]; Folic Acid inhibits the reaction [Doxorubicin results in decreased expression of CASP8 mRNA]
Folic Acid inhibits the reaction [Dietary Fats results in increased expression of CASP8 mRNA]; Folic Acid inhibits the reaction [Vitamin B 12 promotes the reaction [Dietary Fats results in increased expression of CASP8 mRNA]]
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CASP8 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CASP8 gene

PMID:16361273 PMID:20938992 PMID:22206623 PMID:23935743 PMID:29250709 More...

NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699

G

caspase 8 associated protein 2

decreases expression

ISO

Folic Acid results in decreased expression of CASP8AP2 mRNA

NCBI chr 5:51,809,366...51,848,633
Ensembl chr 5:51,810,972...51,848,632

G

caspase 9

multiple interactions
increases expression

ISO
EXP

Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in increased expression of CASP9 protein modified form]
Folic Acid inhibits the reaction [aluminum maltolate results in increased cleavage of CASP9 protein]; Folic Acid inhibits the reaction [Doxorubicin results in decreased expression of CASP9 mRNA]; MIR19A mRNA affects the reaction [Folic Acid inhibits the reaction [aluminum maltolate results in increased cleavage of CASP9 protein]]; MIR19B1 mRNA affects the reaction [Folic Acid inhibits the reaction [aluminum maltolate results in increased cleavage of CASP9 protein]]
Folic Acid inhibits the reaction [Nicotine results in increased expression of CASP9 protein]
Folic Acid results in increased expression of CASP9 protein modified form

PMID:27113042 PMID:29068127 PMID:29972271 PMID:30581319

Ensembl chr 5:159,391,188...159,409,648

G

Cas scaffold protein family member 4

decreases expression

ISO

Folic Acid results in decreased expression of CASS4 mRNA

PMID:21867686 PMID:25629700

NCBI chr 3:181,580,954...181,620,945
Ensembl chr 3:181,581,902...181,620,945

G

castor zinc finger 1

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CASZ1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CASZ1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CASZ1 gene
Folic Acid results in decreased expression of CASZ1 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr 5:164,527,083...164,677,037
Ensembl chr 5:164,527,112...164,677,014

G

catalase

multiple interactions
increases expression
decreases expression

ISO
EXP

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CAT mRNA; [Betaine co-treated with Choline co-treated with Folic Acid co-treated with Methionine co-treated with Vitamin B 12 co-treated with Zinc Sulfate co-treated with Ethanol] results in increased activity of CAT protein; [Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CAT protein; [Folic Acid co-treated with Sodium Bicarbonate] results in decreased activity of CAT protein
Folic Acid results in increased expression of CAT mRNA
Folic Acid deficiency results in decreased expression of CAT
[Melatonin co-treated with Folic Acid] inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein]; [Methionine co-treated with Betaine co-treated with Choline co-treated with Folic Acid] inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein]; Folic Acid inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein]; Folic Acid inhibits the reaction [Nicotine results in decreased activity of CAT protein]; Vitamin B 12 promotes the reaction [Folic Acid inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein]]

PMID:16214333 PMID:20118189 PMID:22206623 PMID:23374533 PMID:23439872 More...

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526

G

caveolin 1

increases expression
multiple interactions

ISO

Folic Acid results in increased expression of CAV1 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CAV1 mRNA

PMID:22206623 PMID:25629700

NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:46,600,738...46,639,740

G

caveolae associated protein 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CAVIN1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CAVIN1 mRNA

PMID:20938992 PMID:22206623

NCBI chr10:86,384,401...86,398,240
Ensembl chr10:86,384,401...86,396,383

G

caveolae associated protein 3

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CAVIN3 mRNA

NCBI chr 1:169,238,384...169,239,973
Ensembl chr 1:169,238,384...169,239,981

G

CACN subunit beta associated regulatory protein

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CBARP mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CBARP gene

PMID:20938992 PMID:22206623

NCBI chr 7:10,217,314...10,225,855
Ensembl chr 7:10,217,328...10,225,854

G

CBFA2/RUNX1 partner transcriptional co-repressor 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CBFA2T2 mRNA; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CBFA2T2 mRNA]

PMID:20938992 PMID:22206623

NCBI chr 3:163,397,160...163,503,409
Ensembl chr 3:163,397,185...163,503,407

G

Cbl proto-oncogene B

decreases expression

ISO

Folic Acid results in decreased expression of CBLB mRNA

NCBI chr11:62,058,829...62,225,904
Ensembl chr11:62,061,653...62,225,778

G

Cbl proto-oncogene C

decreases expression

ISO

Folic Acid results in decreased expression of CBLC mRNA

NCBI chr 1:88,567,930...88,584,709
Ensembl chr 1:88,567,932...88,584,709

G

Cbl proto-oncogene like 1

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of CBLL1 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CBLL1 mRNA

PMID:22206623 PMID:25629700

NCBI chr 6:53,798,712...53,812,890
Ensembl chr 6:53,798,712...53,813,880

G

cerebellin 1 precursor

decreases expression

ISO

Folic Acid results in decreased expression of CBLN1 mRNA

NCBI chr19:35,782,151...35,785,960
Ensembl chr19:35,781,952...35,785,960

G

cerebellin 2 precursor

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CBLN2 gene

NCBI chr18:82,215,210...82,222,648
Ensembl chr18:82,215,220...82,222,648

G

cerebellin 3 precursor

decreases expression

ISO

Folic Acid results in decreased expression of CBLN3 mRNA

NCBI chr15:33,331,919...33,334,428
Ensembl chr15:33,331,919...33,334,428

G

cerebellin 4 precursor

decreases expression

ISO

Folic Acid results in decreased expression of CBLN4 mRNA

NCBI chr 3:181,218,046...181,225,600
Ensembl chr 3:181,218,046...181,225,600

G

carbonyl reductase 2

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CBR2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CBR2 mRNA
Folic Acid results in decreased expression of CBR2 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr10:106,508,964...106,511,614
Ensembl chr10:106,509,136...106,511,180

G

carbonyl reductase 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CBR3 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CBR3 mRNA

PMID:20938992 PMID:22206623

NCBI chr11:46,478,295...46,486,555
Ensembl chr11:46,478,274...46,486,558

G

carbonyl reductase 4

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CBR4 mRNA

NCBI chr16:33,625,734...33,695,067
Ensembl chr16:33,617,399...33,656,832

G

cystathionine beta synthase

increases expression
increases activity
decreases expression
multiple interactions

ISO
EXP

Folic Acid results in increased expression of CBS mRNA
Folic Acid results in increased activity of CBS protein
Folic Acid results in decreased expression of CBS mRNA
[Fatty Acids, Omega-3 co-treated with Folic Acid co-treated with Vitamin B 12 deficiency] results in increased expression of CBS mRNA; [Folic Acid co-treated with Vitamin B 12 deficiency] results in increased expression of CBS mRNA; Folic Acid inhibits the reaction [phenylhydrazine results in decreased activity of CBS protein]; Homocysteine inhibits the reaction [Folic Acid results in increased activity of CBS protein]
Folic Acid deficiency results in decreased expression of CBS protein
[Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in decreased expression of CBS mRNA; [Choline deficiency co-treated with Folic Acid deficiency] affects the expression of CBS mRNA; Folic Acid inhibits the reaction [AGT protein results in decreased expression of CBS mRNA]; Folic Acid inhibits the reaction [AGT protein results in decreased expression of CBS protein]

PMID:21840474 PMID:22959928 PMID:23439872 PMID:24386282 PMID:25003120 More...

NCBI chr20:9,709,394...9,733,925
Ensembl chr20:9,709,395...9,734,066

G

chromobox 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CBX1 gene

NCBI chr10:82,266,746...82,286,431
Ensembl chr10:82,266,759...82,287,242

G

chromobox 2

decreases expression

ISO

Folic Acid results in decreased expression of CBX2 mRNA

NCBI chr10:104,777,054...104,785,922
Ensembl chr10:104,777,056...104,785,926

G

chromobox 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CBX3 mRNA

NCBI chr 4:81,876,155...81,889,912
Ensembl chr 4:81,876,649...81,889,911

G

chromobox 4

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CBX4 mRNA

NCBI chr10:104,835,685...104,841,727
Ensembl chr10:104,835,685...104,841,727

G

chromobox 6

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CBX6 mRNA
Folic Acid results in decreased expression of CBX6 mRNA

PMID:20938992 PMID:25629700

NCBI chr 7:113,253,364...113,263,413
Ensembl chr 7:113,253,364...113,263,413

G

chromobox 7

decreases expression

ISO

Folic Acid results in decreased expression of CBX7 mRNA

NCBI chr 7:113,341,030...113,358,716
Ensembl chr 7:113,341,030...113,358,346

G

chromobox 8

increases expression

ISO

Folic Acid results in increased expression of CBX8 mRNA

NCBI chr10:104,793,062...104,795,500
Ensembl chr10:104,793,062...104,795,500

G

chibby family member 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CBY2 mRNA

NCBI chr15:57,318,820...57,413,687
Ensembl chr15:57,317,988...57,334,505

G

coiled-coil and C2 domain containing 1B

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of CC2D1B; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CC2D1B gene

NCBI chr 5:128,581,962...128,596,045
Ensembl chr 5:128,581,994...128,596,022

G

collagen and calcium binding EGF domains 1

multiple interactions

ISO

[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of CCBE1 mRNA

NCBI chr18:61,849,821...62,093,876
Ensembl chr18:61,853,149...62,094,075

G

coiled-coil domain containing 102A

decreases expression

ISO

Folic Acid results in decreased expression of CCDC102A mRNA

NCBI chr19:10,108,553...10,124,652
Ensembl chr19:10,109,364...10,124,652

G

coiled-coil domain containing 106

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CCDC106 gene

NCBI chr 1:77,808,723...77,812,816
Ensembl chr 1:77,808,723...77,852,105

G

coiled-coil domain containing 107

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CCDC107 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CCDC107 gene

PMID:20938992 PMID:22206623

NCBI chr 5:62,545,273...62,548,711
Ensembl chr 5:62,544,714...62,548,709

G

coiled-coil domain containing 112

decreases expression

ISO

Folic Acid results in decreased expression of CCDC112 mRNA

NCBI chr18:41,184,769...41,218,958
Ensembl chr18:41,184,769...41,218,958

G

coiled-coil domain containing 115

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CCDC115 mRNA]

NCBI chr 9:44,146,287...44,150,250
Ensembl chr 9:44,145,161...44,149,899

G

coiled-coil domain containing 116

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCDC116 mRNA

NCBI chr11:97,346,927...97,354,827
Ensembl chr11:97,346,675...97,354,824

G

coiled-coil domain containing 117

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CCDC117 mRNA

NCBI chr14:84,614,282...84,623,648
Ensembl chr14:84,614,283...84,624,087

G

coiled-coil domain containing 12

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCDC12 mRNA

NCBI chr 8:119,513,007...119,564,802
Ensembl chr 8:119,514,094...119,564,802

G

coiled-coil domain containing 120

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCDC120 mRNA
Folic Acid results in decreased expression of CCDC120 mRNA

PMID:20938992 PMID:25629700

NCBI chr X:17,437,219...17,443,716
Ensembl chr X:17,425,624...17,444,717

G

coiled-coil domain containing 124

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCDC124 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CCDC124 gene

PMID:20938992 PMID:22206623

NCBI chr16:18,600,737...18,606,556
Ensembl chr16:18,600,737...18,606,556

G

coiled-coil domain containing 127

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCDC127 mRNA
Folic Acid results in decreased expression of CCDC127 mRNA

PMID:22206623 PMID:25629700

NCBI chr 1:30,757,010...30,764,473
Ensembl chr 1:30,757,010...30,764,473

G

coiled-coil domain containing 138

decreases expression

ISO

Folic Acid results in decreased expression of CCDC138 mRNA

NCBI chr20:27,037,256...27,115,454
Ensembl chr20:27,038,349...27,115,452

G

coiled-coil domain containing 154

decreases expression

ISO

Folic Acid results in decreased expression of CCDC154 mRNA

NCBI chr10:14,681,938...14,691,757
Ensembl chr10:14,681,923...14,691,759

G

coiled-coil domain containing 157

decreases expression

ISO

Folic Acid results in decreased expression of CCDC157 mRNA

NCBI chr14:83,236,010...83,255,012
Ensembl chr14:83,237,956...83,267,666

G

coiled-coil domain containing 158

increases expression

ISO

Folic Acid results in increased expression of CCDC158 mRNA

NCBI chr14:15,695,456...15,752,896
Ensembl chr14:15,695,512...15,752,941

G

coiled-coil domain containing 159

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCDC159 mRNA

NCBI chr 8:28,733,988...28,742,646
Ensembl chr 8:28,725,003...28,744,890

G

coiled-coil domain containing 162

increases expression

ISO

Folic Acid results in increased expression of CCDC162 mRNA

NCBI chr20:46,627,277...46,820,216
Ensembl chr20:46,627,277...46,818,249

G

coiled-coil domain containing 167

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCDC167 mRNA

NCBI chr20:7,768,425...7,783,181
Ensembl chr20:7,753,072...7,783,181

G

coiled-coil domain containing 174

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CCDC174 mRNA

NCBI chr 4:125,949,203...125,976,179
Ensembl chr 4:125,949,420...125,976,178

G

coiled-coil domain containing 18

increases expression

ISO

Folic Acid results in increased expression of CCDC18 mRNA

NCBI chr14:1,646,725...1,752,581
Ensembl chr14:1,646,809...1,750,470

G

coiled-coil domain containing 181

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCDC181 mRNA

NCBI chr13:79,157,708...79,171,365
Ensembl chr13:79,157,697...79,171,364

G

coiled-coil domain containing 190

multiple interactions

ISO

[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of CCDC190 mRNA

NCBI chr13:84,679,959...84,687,661
Ensembl chr13:84,679,986...84,687,658

G

coiled-coil domain containing 191

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCDC191 mRNA

NCBI chr11:70,241,562...70,312,288
Ensembl chr11:70,241,562...70,312,431

G

coiled-coil domain containing 22

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCDC22 mRNA

NCBI chr X:17,570,184...17,582,130
Ensembl chr X:17,535,659...17,582,130

G

coiled-coil domain containing 3

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCDC3 mRNA

NCBI chr17:77,941,148...78,044,820
Ensembl chr17:77,944,977...78,044,470

G

coiled-coil domain containing 32

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCDC32 mRNA

NCBI chr 3:126,452,293...126,464,845
Ensembl chr 3:126,452,304...126,472,778

G

coiled-coil domain containing 51

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of CCDC51 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCDC51 mRNA

PMID:22206623 PMID:25629700

NCBI chr 8:118,601,002...118,619,943
Ensembl chr 8:118,601,019...118,619,943

G

coiled-coil domain containing 54

increases expression

ISO

Folic Acid results in increased expression of CCDC54 mRNA

NCBI chr11:63,693,017...63,696,114
Ensembl chr11:63,692,105...63,722,348

G

coiled-coil domain containing 6

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCDC6 mRNA
Folic Acid results in decreased expression of CCDC6 mRNA

PMID:22206623 PMID:25629700

NCBI chr20:18,431,243...18,527,227
Ensembl chr20:18,431,243...18,527,227

G

coiled-coil domain containing 61

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCDC61 mRNA

NCBI chr 1:87,665,541...87,685,732
Ensembl chr 1:87,665,541...87,685,732

G

coiled-coil domain containing 68

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCDC68 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCDC68 mRNA

PMID:20938992 PMID:22206623

NCBI chr18:65,817,232...65,859,529
Ensembl chr18:65,786,926...65,859,526

G

coiled-coil domain containing 69

increases expression

ISO

Folic Acid results in increased expression of CCDC69 mRNA

NCBI chr10:39,673,984...39,701,080
Ensembl chr10:39,673,985...39,700,579

G

coiled-coil domain containing 71

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of CCDC71 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCDC71 mRNA

PMID:22206623 PMID:25629700

NCBI chr 8:118,025,192...118,040,143
Ensembl chr 8:118,003,244...118,046,209

G

coiled-coil domain containing 71-like

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCDC71L mRNA

NCBI chr 6:54,687,474...54,691,566
Ensembl chr 6:54,617,540...55,014,344

G

coiled-coil domain containing 73

decreases expression

ISO

Folic Acid results in decreased expression of CCDC73 mRNA

NCBI chr 3:111,737,771...111,879,588
Ensembl chr 3:111,737,730...111,880,105

G

coiled-coil domain containing 77

decreases expression

ISO

Folic Acid results in decreased expression of CCDC77 mRNA

NCBI chr 4:155,206,402...155,238,235
Ensembl chr 4:155,193,275...155,239,207

G

coiled-coil domain containing 80

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCDC80 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCDC80 mRNA

PMID:20938992 PMID:22206623

NCBI chr11:69,191,188...69,224,844
Ensembl chr11:69,191,189...69,224,844

G

coiled-coil domain containing 82

increases expression

ISO

Folic Acid results in increased expression of CCDC82 mRNA

NCBI chr 8:18,509,293...18,665,008
Ensembl chr 8:18,509,382...18,550,529

G

coiled-coil domain containing 85A

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CCDC85A gene
Folic Acid results in decreased expression of CCDC85A mRNA

PMID:20938992 PMID:25629700

NCBI chr14:106,327,580...106,560,205
Ensembl chr14:106,327,580...106,560,165

G

coiled-coil domain containing 86

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CCDC86 mRNA]

NCBI chr 1:217,015,059...217,021,439
Ensembl chr 1:217,014,848...217,021,468

G

coiled coil domain containing 88A

multiple interactions

ISO

[Doxorubicin co-treated with Folic Acid] results in increased expression of CCDC88A mRNA

NCBI chr14:107,304,654...107,456,104
Ensembl chr14:107,305,199...107,453,285

G

coiled-coil domain containing 88B

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CCDC88B gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CCDC88B mRNA]

PMID:20938992 PMID:22206623

NCBI chr 1:213,466,139...213,482,099
Ensembl chr 1:213,461,963...213,522,302

G

coiled-coil domain containing 88C

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CCDC88C gene

NCBI chr 6:125,899,337...126,019,162
Ensembl chr 6:125,899,526...126,018,865

G

coiled-coil domain containing 9

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CCDC9 gene

NCBI chr 1:86,105,717...86,119,811
Ensembl chr 1:86,105,800...86,119,884

G

coiled-coil domain containing 90B

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CCDC90B gene
Folic Acid results in decreased expression of CCDC90B mRNA

PMID:20938992 PMID:25629700

NCBI chr 1:156,045,192...156,058,750
Ensembl chr 1:156,045,138...156,061,403

G

coiled-coil domain containing 91

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CCDC91 mRNA

NCBI chr 4:182,132,931...182,304,948
Ensembl chr 4:182,132,942...182,304,948

G

coiled-coil domain containing 92

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCDC92 mRNA

NCBI chr12:37,457,676...37,484,080
Ensembl chr12:37,457,068...37,484,327

G

coiled-coil domain containing 97

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCDC97 mRNA

NCBI chr 1:90,347,003...90,354,809
Ensembl chr 1:90,347,008...90,354,764

G

coiled-coil domain containing 9B

decreases expression

ISO

Folic Acid results in decreased expression of CCDC9B mRNA

NCBI chr 3:126,190,039...126,198,931
Ensembl chr 3:126,192,232...126,199,580

G

coiled-coil alpha-helical rod protein 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCHCR1 mRNA

NCBI chr20:3,210,383...3,223,187
Ensembl chr20:3,210,384...3,222,765

G

cholecystokinin

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCK mRNA

NCBI chr 8:130,031,012...130,037,702
Ensembl chr 8:130,031,013...130,037,686

G

C-C motif chemokine ligand 19

increases expression

ISO

Folic Acid results in increased expression of CCL19 mRNA

NCBI chr 5:61,759,220...61,761,164
Ensembl chr 5:61,759,220...61,772,022

G

C-C motif chemokine ligand 2

multiple interactions
increases expression
decreases expression

ISO
EXP

[Folic Acid affects the susceptibility to Pemetrexed] which affects the expression of CCL2 mRNA; Folic Acid deficiency results in increased expression of and results in increased secretion of CCL2 protein; Folic Acid inhibits the reaction [Homocysteine results in increased expression of CCL2 mRNA]; Folic Acid inhibits the reaction [TGFB1 protein results in increased expression of CCL2 mRNA]; SB 203580 inhibits the reaction [Folic Acid deficiency results in increased expression of and results in increased secretion of CCL2 protein]; SB 203580 inhibits the reaction [Folic Acid deficiency results in increased expression of CCL2 mRNA]
Folic Acid results in increased expression of CCL2 mRNA
Folic Acid deficiency results in increased expression of CCL2 mRNA; Folic Acid deficiency results in increased expression of CCL2 protein
[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCL2 mRNA; Folic Acid affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of CCL2 mRNA]; Folic Acid affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of CCL2 protein]; Folic Acid affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the methylation of CCL2 promoter]; Metformin inhibits the reaction [Folic Acid results in increased expression of CCL2 mRNA]
[Choline co-treated with Betaine co-treated with Vitamin B 12 co-treated with Folic Acid co-treated with Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of CCL2 mRNA; Folic Acid inhibits the reaction [Methionine results in increased expression of CCL2 mRNA]; Folic Acid inhibits the reaction [Methionine results in increased expression of CCL2 protein]
Folic Acid results in decreased expression of CCL2 mRNA; Folic Acid results in decreased expression of CCL2 protein

PMID:16491109 PMID:16845898 PMID:17868882 PMID:19152916 PMID:20938992 More...

NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875

G

C-C motif chemokine ligand 21

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CCL21A mRNA

NCBI chr 5:61,776,411...61,777,515
Ensembl chr 5:61,776,413...61,777,540

G

C-C motif chemokine ligand 25

decreases expression

ISO

Folic Acid results in decreased expression of CCL25 mRNA

NCBI chr12:7,505,231...7,514,402
Ensembl chr12:7,505,235...7,514,385

G

C-C motif chemokine ligand 26

decreases expression

ISO

Folic Acid results in decreased expression of CCL26 mRNA

NCBI chr12:26,745,972...26,750,924

G

C-C motif chemokine ligand 3

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCL3 mRNA

NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439

G

C-C motif chemokine ligand 4

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCL4 mRNA

NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,950,289...68,965,722

G

C-C motif chemokine ligand 5

increases expression

ISO

Folic Acid results in increased expression of CCL5 mRNA

PMID:25629700 PMID:28752528 PMID:34619300

NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884

G

C-C motif chemokine ligand 7

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCL7 mRNA
Folic Acid results in increased expression of CCL7 mRNA

PMID:20938992 PMID:25629700

NCBI chr10:67,514,095...67,515,945
Ensembl chr10:67,514,091...67,515,947

G

C-C motif chemokine ligand 9

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCL6 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCL6 mRNA

PMID:20938992 PMID:22206623

NCBI chr10:68,863,994...68,868,928
Ensembl chr10:68,863,995...68,868,877

G

CCM2 scaffold protein

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CCM2 mRNA

NCBI chr14:85,632,338...85,678,016
Ensembl chr14:85,632,001...85,678,028

G

cellular communication network factor 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CCN1 gene
Folic Acid inhibits the reaction [sodium arsenite results in decreased expression of CCN1 protein]

PMID:20938992 PMID:37682722

NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:237,222,432...237,225,883

G

cellular communication network factor 2

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of CCN2; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CCN2 gene; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCN2 mRNA
Folic Acid results in decreased expression of CCN2 mRNA

PMID:20938992 PMID:25629700

NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:22,621,501...22,624,976

G

cellular communication network factor 4

affects expression

ISO

Folic Acid affects the expression of CCN4 mRNA

NCBI chr 7:100,534,578...100,566,287
Ensembl chr 7:100,534,505...100,563,094

G

cellular communication network factor 5

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCN5 mRNA
Folic Acid results in decreased expression of WISP2 mRNA

PMID:20938992 PMID:25629700

NCBI chr 3:172,910,670...172,922,064
Ensembl chr 3:172,910,681...172,922,062

G

cyclin A1

decreases expression

ISO

Folic Acid results in decreased expression of CCNA1 mRNA

NCBI chr 2:141,383,352...141,428,205
Ensembl chr 2:141,382,468...141,393,300

G

cyclin A2

multiple interactions
increases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCNA2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCNA2 mRNA
Folic Acid results in increased expression of CCNA2 mRNA
[Folic Acid co-treated with Camptothecin] results in decreased expression of CCNA2 mRNA; [Folic Acid co-treated with Doxorubicin] results in decreased expression of CCNA2 mRNA; [Folic Acid co-treated with Methyl Methanesulfonate] results in decreased expression of CCNA2 mRNA; [Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of CCNA2 mRNA

PMID:20938992 PMID:22206623 PMID:24657277 PMID:25841994 PMID:30581319

NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701

G

cyclin B1

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCNB1 mRNA
Folic Acid results in increased expression of CCNB1 mRNA
[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of CCNB1 mRNA

PMID:20938992 PMID:24657277 PMID:25629700

NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225

G

cyclin B2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCNB2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CCNB2 gene
[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of CCNB2 mRNA

PMID:20938992 PMID:22206623 PMID:24657277

NCBI chr 8:79,968,459...79,981,717
Ensembl chr 8:79,968,465...79,981,682

G

cyclin D1

affects expression
increases expression
multiple interactions
decreases expression

ISO

Folic Acid affects the expression of CCND1 mRNA
Folic Acid results in increased expression of CCND1 mRNA
Folic Acid affects the reaction [Benzo(a)pyrene results in increased expression of CCND1 protein]
Folic Acid results in decreased expression of CCND1 mRNA
[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCND1 mRNA; trichostatin A affects the reaction [Folic Acid affects the expression of CCND1 mRNA]

PMID:16361273 PMID:20938992 PMID:21867686 PMID:25629700 PMID:30020114 More...

NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810

G

cyclin D2

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CCND2 mRNA]

NCBI chr 4:161,653,048...161,675,422
Ensembl chr 4:161,653,048...161,680,301
Ensembl chr 4:161,653,048...161,680,301

G

cyclin D3

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of CCND3 mRNA
Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CCND3 mRNA]

PMID:11723236 PMID:22206623 PMID:25629700

NCBI chr 9:20,891,696...20,987,199
Ensembl chr 9:20,891,704...20,987,033

G

cyclin D1 binding protein 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCNDBP1 mRNA

NCBI chr 3:128,416,105...128,427,985
Ensembl chr 3:128,416,054...128,436,008

G

cyclin E1

affects expression

ISO

Folic Acid affects the expression of CCNE1 mRNA

NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:99,918,674...99,927,822

G

cyclin E2

decreases expression

ISO

Folic Acid results in decreased expression of CCNE2 mRNA

NCBI chr 5:29,082,169...29,094,879
Ensembl chr 5:29,082,703...29,094,882

G

cyclin G1

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCNG1 mRNA
Folic Acid results in decreased expression of CCNG1 mRNA

PMID:22206623 PMID:25629700

NCBI chr10:25,678,503...25,684,876
Ensembl chr10:25,677,885...25,683,766

G

cyclin G2

multiple interactions

ISO

[Ethanol co-treated with Folic Acid] results in increased expression of CCNG2 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCNG2 mRNA

PMID:22206623 PMID:23378141

NCBI chr14:15,088,694...15,097,190
Ensembl chr14:15,088,695...15,096,206

G

cyclin I

decreases expression

ISO

Folic Acid results in decreased expression of CCNI mRNA

NCBI chr14:15,164,047...15,186,885
Ensembl chr14:15,164,095...15,186,885

G

cyclin J

decreases expression

ISO

Folic Acid results in decreased expression of CCNJ mRNA

NCBI chr 1:249,608,991...249,626,798
Ensembl chr 1:249,608,969...249,626,794

G

cyclin J-like

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCNJL mRNA
Folic Acid results in decreased expression of CCNJL mRNA

PMID:20938992 PMID:25629700

NCBI chr10:28,497,144...28,554,877
Ensembl chr10:28,496,990...28,554,877

G

cyclin L1

decreases expression

ISO

Folic Acid results in decreased expression of CCNL1 mRNA

NCBI chr 2:152,495,169...152,508,855
Ensembl chr 2:152,495,172...152,507,468

G

cyclin L2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CCNL2 gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CCNL2 mRNA]

PMID:20938992 PMID:22206623

NCBI chr 5:171,698,951...171,711,037
Ensembl chr 5:171,699,689...171,711,231

G

cyclin O

decreases expression

ISO

Folic Acid results in decreased expression of CCNO mRNA

NCBI chr 2:46,364,074...46,367,113
Ensembl chr 2:46,350,717...46,367,113

G

cyclin Q

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCNQ mRNA

NCBI chr10:64,144,560...64,145,723
Ensembl chr10:64,144,555...64,145,911

G

cyclin T1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCNT1 mRNA

NCBI chr 7:131,566,176...131,596,988
Ensembl chr 7:131,566,176...131,596,938

G

cyclin T2

decreases expression

ISO

Folic Acid results in decreased expression of CCNT2 mRNA

NCBI chr13:41,804,007...41,845,641
Ensembl chr13:41,804,046...41,844,488

G

cyclin Y

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CCNY gene
Folic Acid results in decreased expression of CCNY mRNA

PMID:20938992 PMID:25629700

NCBI chr17:62,079,925...62,207,780
Ensembl chr17:62,079,925...62,207,979

G

cyclin Y-like 1

decreases expression

ISO

Folic Acid results in decreased expression of CCNYL1 mRNA

PMID:21867686 PMID:25629700

NCBI chr 9:73,565,484...73,601,926
Ensembl chr 9:73,565,402...73,601,922

G

centriolar coiled-coil protein 110

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of CCP110 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CCP110 mRNA

PMID:21867686 PMID:22206623

NCBI chr 1:182,475,571...182,504,235
Ensembl chr 1:182,476,422...182,504,232

G

cell cycle progression 1

decreases expression

ISO

Folic Acid results in decreased expression of CCPG1 mRNA

NCBI chr 8:82,600,677...82,633,082
Ensembl chr 8:82,600,536...82,660,246

G

C-C motif chemokine receptor 1

multiple interactions

ISO

[Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCR1 mRNA

NCBI chr 8:132,433,711...132,439,266
Ensembl chr 8:132,431,592...132,439,374

G

C-C motif chemokine receptor 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCR2 mRNA

NCBI chr 8:132,611,883...132,619,106
Ensembl chr 8:132,611,410...132,620,059

G

C-C motif chemokine receptor 6

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CCR6 mRNA

NCBI chr 1:55,022,037...55,055,857
Ensembl chr 1:55,021,833...55,046,059

G

C-C motif chemokine receptor 7

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCR7 mRNA

NCBI chr10:84,594,399...84,604,514
Ensembl chr10:84,593,594...84,604,501

G

C-C motif chemokine receptor 9

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCR9 mRNA; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CCR9 mRNA]

PMID:20938992 PMID:22206623

NCBI chr 8:132,273,581...132,287,651
Ensembl chr 8:132,273,544...132,287,883

G

C-C motif chemokine receptor like 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCRL2 mRNA

NCBI chr 8:119,912,671...119,915,313
Ensembl chr 8:119,911,288...119,922,380

G

copper chaperone for superoxide dismutase

multiple interactions

ISO

[Ethanol co-treated with Folic Acid] results in increased expression of CCS mRNA

NCBI chr 1:211,543,192...211,564,354
Ensembl chr 1:211,542,701...211,564,260

G

coiled-coil serine-rich protein 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CCSER2 mRNA

NCBI chr16:12,633,374...12,746,045
Ensembl chr16:12,637,083...12,746,003

G

chaperonin containing TCP1 subunit 2

decreases expression

ISO

Folic Acid results in decreased expression of CCT2 mRNA

NCBI chr 7:54,578,654...54,591,428
Ensembl chr 7:54,578,663...54,592,977

G

chaperonin containing TCP1 subunit 3

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CCT3 mRNA]

NCBI chr 2:176,063,529...176,088,180
Ensembl chr 2:176,063,526...176,089,925

G

chaperonin containing TCP1 subunit 4

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCT4 mRNA

NCBI chr14:101,193,057...101,205,935
Ensembl chr14:101,192,772...101,205,770

G

chaperonin containing TCP1 subunit 5

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCT5 mRNA
Folic Acid results in decreased expression of CCT5 mRNA

PMID:21867686 PMID:22206623

NCBI chr 2:84,302,621...84,313,773
Ensembl chr 2:84,302,623...84,313,779

G

chaperonin containing TCP1 subunit 6A

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CCT6A mRNA]

NCBI chr12:32,508,842...32,519,072
Ensembl chr12:32,508,675...32,519,119

G

chaperonin containing TCP1 subunit 7

multiple interactions
increases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCT7 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CCT7 gene
Folic Acid results in increased expression of CCT7 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr 4:119,546,730...119,563,973
Ensembl chr 4:119,546,730...119,563,973

G

chaperonin containing TCP1 subunit 8

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCT8 mRNA

NCBI chr11:40,196,619...40,208,328
Ensembl chr11:40,196,619...40,208,328

G

CCZ1 homolog, vacuolar protein trafficking and biogenesis associated

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCZ1 mRNA
Folic Acid results in decreased expression of CCZ1 mRNA

PMID:22206623 PMID:25629700

NCBI chr12:15,714,768...15,738,273
Ensembl chr12:15,714,748...15,738,268

G

CD109 molecule

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CD109 gene
Folic Acid results in decreased expression of CD109 mRNA

PMID:20938992 PMID:25629700

NCBI chr 8:88,334,736...88,449,463
Ensembl chr 8:88,334,736...88,449,462

G

CD14 molecule

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CD14 mRNA; [Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of CD14 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD14 mRNA

PMID:20938992 PMID:22206623 PMID:29127188

NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292

G

CD151 molecule (Raph blood group)

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CD151 mRNA

NCBI chr 1:205,994,300...205,998,307
Ensembl chr 1:205,994,738...205,998,784

G

CD164 molecule

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CD164 gene

NCBI chr20:46,606,439...46,618,015
Ensembl chr20:46,606,107...46,638,649

G

CD164 molecule like 2

decreases expression

ISO

Folic Acid results in decreased expression of CD164L2 mRNA

NCBI chr 5:150,698,662...150,711,622
Ensembl chr 5:150,707,667...150,711,631

G

CD180 molecule

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD180 mRNA

NCBI chr 2:35,589,889...35,602,837
Ensembl chr 2:35,589,451...35,603,982

G

Cd200 molecule

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CD200 mRNA

NCBI chr11:68,916,200...68,943,570
Ensembl chr11:68,916,224...68,943,569

G

CD200 receptor 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD200R1 mRNA

NCBI chr11:69,392,943...69,427,213
Ensembl chr11:69,392,975...69,427,128

G

CD207 molecule

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD207 mRNA

NCBI chr 4:117,712,879...117,719,191
Ensembl chr 4:117,712,879...117,719,191

G

CD226 molecule

increases expression

ISO

Folic Acid results in increased expression of CD226 mRNA

NCBI chr18:84,723,330...84,819,836
Ensembl chr18:84,725,242...84,819,835

G

CD24 molecule

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CD24A mRNA; [Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of CD24A mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD24A mRNA
Folic Acid results in decreased expression of CD24A mRNA

PMID:20938992 PMID:22206623 PMID:25629700 PMID:29127188

NCBI chr20:48,655,549...48,661,786
Ensembl chr20:48,655,805...48,661,785

G

CD244 molecule

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD244 mRNA

NCBI chr13:86,583,727...86,606,902
Ensembl chr13:86,584,826...86,616,009

G

Cd247 molecule

increases expression

ISO

Folic Acid results in increased expression of CD247 mRNA

NCBI chr13:80,576,264...80,651,422
Ensembl chr13:80,576,202...80,655,248

G

CD27 molecule

decreases expression

ISO

Folic Acid results in decreased expression of CD27 mRNA

NCBI chr 4:159,716,932...159,721,823
Ensembl chr 4:159,716,935...159,721,823

G

CD274 molecule

multiple interactions

ISO

[Folic Acid deficiency co-treated with Methotrexate] results in increased expression of CD274 mRNA

NCBI chr 1:236,526,215...236,549,956
Ensembl chr 1:236,496,463...236,549,951

G

Cd2 (cytoplasmic tail) binding protein 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CD2BP2 gene

NCBI chr 1:191,239,899...191,244,395
Ensembl chr 1:191,239,901...191,243,398

G

Cd300a molecule

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD300A mRNA

NCBI chr10:100,428,826...100,441,693
Ensembl chr10:100,428,826...100,442,958

G

CD300C molecule 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD300C2 mRNA

NCBI chr10:100,752,301...100,757,549
Ensembl chr10:100,752,621...100,757,332

G

Cd300 molecule-like family member D

decreases expression

ISO

Folic Acid results in decreased expression of CD300LD mRNA

NCBI chr10:100,581,960...100,614,868
Ensembl chr10:100,581,960...100,614,858

G

Cd300 molecule-like family member F

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD300LF mRNA
Folic Acid results in increased expression of CD300LF mRNA

PMID:20938992 PMID:25629700

NCBI chr10:100,858,924...100,875,111
Ensembl chr10:100,858,924...100,875,022

G

CD302 molecule

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CD302 mRNA

NCBI chr 3:65,131,017...65,164,737
Ensembl chr 3:65,113,102...65,164,737

G

CD320 molecule

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CD320 mRNA

NCBI chr 7:15,328,320...15,334,138
Ensembl chr 7:15,311,286...15,334,138

G

CD34 molecule

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CD34 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD34 mRNA

PMID:20938992 PMID:22206623

NCBI chr13:109,008,786...109,029,317
Ensembl chr13:109,008,623...109,029,315

G

CD36 molecule

multiple interactions
decreases expression

ISO
EXP

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CD36 mRNA; [Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of CD36 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD36 mRNA
Folic Acid deficiency results in decreased expression of CD36 mRNA

PMID:19566968 PMID:20938992 PMID:22206623 PMID:22872676 PMID:29127188 More...

NCBI chr 4:18,209,088...18,302,142

G

CD37 molecule

multiple interactions
increases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CD37 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD37 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CD37 gene
Folic Acid results in increased expression of CD37 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr 1:104,855,622...104,861,111
Ensembl chr 1:104,849,166...104,861,276

G

CD3 epsilon subunit of T-cell receptor complex

multiple interactions
decreases expression

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CD3E mRNA]
Folic Acid results in decreased expression of CD3E mRNA

PMID:22206623 PMID:25629700

NCBI chr 8:54,200,617...54,211,770
Ensembl chr 8:54,200,617...54,211,876

G

CD40 molecule

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD40 mRNA
[Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in decreased expression of CD40 mRNA

PMID:20938992 PMID:30116142

NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:174,209,719...174,224,847

G

CD44 molecule

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD44 mRNA
Folic Acid results in decreased expression of CD44 mRNA

PMID:20938992 PMID:25629700

NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:109,612,054...109,699,424

G

Cd47 molecule

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CD47 mRNA

NCBI chr11:64,374,816...64,438,763
Ensembl chr11:64,377,926...64,438,272

G

Cd48 molecule

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CD48 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD48 mRNA
Folic Acid results in decreased expression of CD48 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr13:86,717,960...86,741,540
Ensembl chr13:86,717,961...86,742,942

G

CD52 molecule

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD52 mRNA

NCBI chr 5:151,603,537...151,605,096
Ensembl chr 5:151,603,524...151,605,086

G

Cd53 molecule

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD53 mRNA

NCBI chr 2:197,040,369...197,087,925
Ensembl chr 2:197,040,369...197,218,593

G

CD55 molecule (Cromer blood group)

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CD55 mRNA]

NCBI chr13:44,409,574...44,438,913
Ensembl chr13:44,409,587...44,438,107

G

CD59b molecule

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CD59B mRNA

NCBI chr 3:110,914,008...110,932,489
Ensembl chr 3:110,914,091...110,935,310

G

Cd5 molecule-like

decreases expression

ISO

Folic Acid results in decreased expression of CD5L mRNA

NCBI chr 2:175,088,915...175,099,928
Ensembl chr 2:175,088,884...175,099,926

G

Cd63 molecule

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD63 mRNA

NCBI chr 7:1,909,538...1,924,937
Ensembl chr 7:1,922,169...1,924,938

G

Cd68 molecule

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD68 mRNA
Folic Acid results in increased expression of CD68 mRNA; Folic Acid results in increased expression of CD68 protein

PMID:20938992 PMID:34619300

NCBI chr10:54,880,562...54,882,441
Ensembl chr10:54,880,563...54,882,540

G

Cd80 molecule

decreases expression

ISO

Folic Acid results in decreased expression of CD80 mRNA

NCBI chr11:75,760,073...75,798,978
Ensembl chr11:75,760,147...75,797,540

G

Cd81 molecule

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CD81 mRNA

NCBI chr 1:207,665,274...207,681,094
Ensembl chr 1:207,664,885...207,681,092

G

CD83 molecule

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD83 mRNA

NCBI chr17:21,093,281...21,113,223
Ensembl chr17:21,093,281...21,113,047

G

CD84 molecule

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD84 mRNA

NCBI chr13:86,859,979...86,899,984
Ensembl chr13:86,859,990...86,894,318

G

CD9 molecule

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CD9 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD9 mRNA

PMID:20938992 PMID:22206623

NCBI chr 4:159,942,553...159,975,463
Ensembl chr 4:159,942,560...159,975,444

G

CD93 molecule

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CD93 mRNA

NCBI chr 3:156,345,019...156,351,537
Ensembl chr 3:156,345,019...156,351,537

G

CD99 molecule (Xg blood group)

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CD99 mRNA

NCBI chr20:56,000,494...56,005,140

G

CD99 molecule-like 2

decreases expression

ISO

Folic Acid results in decreased expression of CD99L2 mRNA

NCBI chr15:6,861,242...6,906,838
Ensembl chr15:6,864,268...6,906,952

G

cytidine deaminase

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CDA mRNA
Folic Acid results in decreased expression of CDA mRNA

PMID:20938992 PMID:25629700

NCBI chr 5:155,839,929...155,866,541
Ensembl chr 5:155,839,929...155,866,541

G

cytidine and dCMP deaminase domain containing 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CDADC1 mRNA

NCBI chr15:37,902,789...37,934,853
Ensembl chr15:37,886,258...37,931,920

G

cell division cycle 123

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CDC123 mRNA]

NCBI chr17:77,368,376...77,412,659
Ensembl chr17:77,368,397...77,412,659

G

cell division cycle 14B

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CDC14B mRNA]

NCBI chr17:850,272...938,972
Ensembl chr17:850,390...971,164

G

cell division cycle 20

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CDC20 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CDC20 gene
[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of CDC20 mRNA

PMID:20938992 PMID:22206623 PMID:24657277

NCBI chr 5:137,251,596...137,255,799
Ensembl chr 5:137,251,596...137,255,799

G

cell division cycle 25A

multiple interactions

ISO

[Ethanol co-treated with Folic Acid] results in decreased expression of CDC25A mRNA

NCBI chr 8:118,742,824...118,761,190
Ensembl chr 8:118,742,426...118,761,188

G

cell division cycle 25B

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CDC25B mRNA
Folic Acid results in decreased expression of CDC25B mRNA

PMID:20938992 PMID:25629700

NCBI chr 3:138,860,148...138,870,287
Ensembl chr 3:138,860,130...138,870,492

G

cell division cycle 25C

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CDC25C mRNA

NCBI chr18:26,608,483...26,630,292
Ensembl chr18:26,609,959...26,630,292

G

cell division cycle 26

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CDC26 mRNA

NCBI chr 5:80,861,658...80,875,326
Ensembl chr 5:80,861,659...80,875,326

G

cell division cycle 27

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CDC27 mRNA

NCBI chr10:89,900,676...89,949,770
Ensembl chr10:89,900,684...89,949,770

G

cell division cycle 34, ubiquitin conjugating enzyme

multiple interactions
increases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CDC34 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CDC34 gene
Folic Acid results in increased expression of CDC34 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr 7:10,668,209...10,674,206
Ensembl chr 7:10,668,210...10,674,526

G

cell division cycle 42

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CDC42 mRNA
Folic Acid results in decreased expression of CDC42 mRNA

PMID:22206623 PMID:25629700

NCBI chr 5:154,838,478...154,876,629
Ensembl chr 5:154,839,631...154,876,627

G

CDC42 binding protein kinase beta

decreases expression

ISO

Folic Acid results in decreased expression of CDC42BPB mRNA

NCBI chr 6:136,154,905...136,241,259
Ensembl chr 6:136,154,905...136,237,570

G

CDC42 effector protein 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CDC42EP2 mRNA

NCBI chr 1:212,631,317...212,640,231
Ensembl chr 1:212,629,881...212,640,234

G

CDC42 effector protein 3

decreases expression

ISO

Folic Acid results in decreased expression of CDC42EP3 mRNA

NCBI chr 6:21,463,081...21,483,553
Ensembl chr 6:21,461,762...21,508,540

G

CDC42 effector protein 4

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CDC42EP4 mRNA

NCBI chr10:99,271,750...99,298,551
Ensembl chr10:99,267,540...99,300,168

G

CDC42 small effector 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CDC42SE1 mRNA; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CDC42SE1 mRNA]
Folic Acid results in decreased expression of CDC42SE1 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr 2:185,494,692...185,502,519
Ensembl chr 2:185,496,547...185,502,514

G

CDC42 small effector 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CDC42SE2 mRNA

NCBI chr10:39,337,269...39,405,772
Ensembl chr 1:100,424,547...100,424,801
Ensembl chr10:100,424,547...100,424,801

G

cell division cycle 5-like

multiple interactions

ISO

[Doxorubicin co-treated with Folic Acid] results in increased expression of CDC5L mRNA

NCBI chr 9:23,062,397...23,100,901
Ensembl chr 9:23,062,205...23,100,899

G

cell division cycle 6

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CDC6 gene

NCBI chr10:84,360,361...84,374,239
Ensembl chr10:84,360,381...84,374,241

G

cell division cycle associated 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CDCA2 mRNA

NCBI chr15:46,071,360...46,117,524
Ensembl chr15:46,071,360...46,116,639

G

cell division cycle associated 5

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CDCA5 mRNA

NCBI chr 1:212,807,863...212,821,313
Ensembl chr 1:212,804,014...212,821,309

G

cell division cycle associated 7

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CDCA7 mRNA

NCBI chr 3:77,730,315...77,740,950
Ensembl chr 3:77,729,970...77,740,947

G

cell division cycle associated 8

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CDCA8 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CDCA8 mRNA
[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of CDCA8 mRNA

PMID:20938992 PMID:22206623 PMID:24657277

NCBI chr 5:142,461,082...142,483,336
Ensembl chr 5:142,461,084...142,483,283

G

CUB domain containing protein 1

decreases expression

ISO

Folic Acid results in decreased expression of CDCP1 mRNA

NCBI chr 8:131,706,140...131,742,799
Ensembl chr 8:131,706,140...131,742,877

G

cadherin 1

decreases expression
increases expression
multiple interactions

ISO

Folic Acid results in decreased expression of CDH1 mRNA; Folic Acid results in decreased expression of CDH1 protein
Folic Acid deficiency results in increased expression of CDH1 mRNA; Folic Acid deficiency results in increased expression of CDH1 protein; Folic Acid results in increased expression of CDH1 mRNA; Folic Acid results in increased expression of CDH1 protein
[Ethanol co-treated with Folic Acid] results in increased expression of CDH1 mRNA; CADM1 protein affects the reaction [Folic Acid results in increased expression of CDH1 protein]
6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride inhibits the reaction [Folic Acid results in decreased expression of CDH1 protein]; 6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride promotes the reaction [pyrazolanthrone inhibits the reaction [Folic Acid results in decreased expression of CDH1 protein]]; [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CDH1 mRNA; [[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of MIR155 mRNA] which results in increased expression of CDH1 protein; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CDH1 protein; Decitabine inhibits the reaction [Folic Acid results in decreased expression of CDH1 protein]; Decitabine promotes the reaction [Folic Acid results in decreased expression of CDH1 mRNA]; pyrazolanthrone inhibits the reaction [Folic Acid results in decreased expression of CDH1 protein]; pyrazolanthrone promotes the reaction [6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride inhibits the reaction [Folic Acid results in decreased expression of CDH1 protein]]; trichostatin A inhibits the reaction [Folic Acid results in decreased expression of CDH1 mRNA]; trichostatin A inhibits the reaction [Folic Acid results in decreased expression of CDH1 protein]

PMID:17868486 PMID:20548288 PMID:22206623 PMID:23378141 PMID:28639913 More...

NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565

G

cadherin 10

decreases expression

ISO

Folic Acid results in decreased expression of CDH10 mRNA

NCBI chr 2:70,355,521...70,577,880
Ensembl chr 2:70,357,217...70,578,332

G

cadherin 11

decreases expression

ISO

Folic Acid results in decreased expression of CDH11 mRNA

NCBI chr19:2,152,961...2,312,140
Ensembl chr19:2,154,840...2,312,140

G

cadherin 13

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of CDH13 mRNA
Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CDH13 mRNA]

PMID:11723236 PMID:22206623

NCBI chr19:63,258,251...64,296,122
Ensembl chr19:63,258,122...64,296,119

G

cadherin 15

decreases expression

ISO

Folic Acid results in decreased expression of CDH15 mRNA

NCBI chr19:67,812,169...67,834,986
Ensembl chr19:67,812,164...67,834,985

G

cadherin 18

decreases expression

ISO

Folic Acid results in decreased expression of CDH18 mRNA

NCBI chr 2:74,548,681...75,550,720
Ensembl chr 2:75,075,595...75,550,720

G

cadherin 19

increases expression

ISO

Folic Acid results in increased expression of CDH19 mRNA

NCBI chr13:28,450,361...28,561,932
Ensembl chr13:28,451,283...28,533,753

G

cadherin 2

increases expression

ISO

Folic Acid results in increased expression of CDH2 mRNA

PMID:25629700 PMID:36354958 PMID:39617304

NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288

G

cadherin 22

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CDH22 gene

NCBI chr 3:174,264,869...174,389,940
Ensembl chr 3:174,264,869...174,390,142

G

cadherin 3

increases expression
decreases expression
multiple interactions

ISO

Folic Acid results in increased expression of CDH3 mRNA
Folic Acid deficiency results in decreased expression of CDH3 protein
[Folic Acid deficiency results in increased abundance of Homocysteine] which results in decreased expression of CDH3 mRNA; [Folic Acid deficiency results in increased abundance of Homocysteine] which results in decreased expression of CDH3 protein; CYBB mutant form inhibits the reaction [[Folic Acid deficiency results in increased abundance of Homocysteine] which results in decreased expression of CDH3 mRNA]; CYBB mutant form inhibits the reaction [[Folic Acid deficiency results in increased abundance of Homocysteine] which results in decreased expression of CDH3 protein]; CYBB mutant form inhibits the reaction [Folic Acid deficiency results in decreased expression of CDH3 protein]

PMID:17868486 PMID:21647593

NCBI chr19:51,303,414...51,353,900
Ensembl chr19:51,300,083...51,354,257

G

cadherin 4

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CDH4 gene

NCBI chr 3:186,902,763...187,381,020
Ensembl chr 3:186,902,751...187,381,020

G

cadherin 5

decreases expression

ISO

Folic Acid results in decreased expression of CDH5 mRNA

NCBI chr19:821,875...860,931
Ensembl chr19:822,464...860,822

G

cadherin 7

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CDH7 gene

NCBI chr13:27,186,223...27,336,076
Ensembl chr13:27,187,257...27,336,023

G

cadherin 8

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CDH8 gene

NCBI chr19:5,494,552...5,901,950
Ensembl chr19:5,500,221...5,902,627

G

cadherin 9

multiple interactions

ISO

[Ethanol co-treated with Folic Acid] results in increased expression of CDH9 mRNA

NCBI chr 2:67,954,708...68,094,371
Ensembl chr 2:67,955,166...68,094,365

G

cadherin-related family member 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CDHR2 mRNA

NCBI chr17:9,881,979...9,917,698
Ensembl chr17:9,881,979...9,917,698

G

cyclin-dependent kinase 1

multiple interactions
decreases expression

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of CDK1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CDK1 mRNA
Folic Acid results in decreased expression of CDK1 mRNA
[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of CDK1 mRNA

PMID:20938992 PMID:24657277 PMID:25629700 PMID:33549593

NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455

G

cyclin-dependent kinase 10

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CDK10 mRNA]

NCBI chr19:68,168,040...68,184,923
Ensembl chr19:68,169,874...68,177,599

G

cyclin-dependent kinase 12

decreases expression

ISO

Folic Acid results in decreased expression of CDK12 mRNA

NCBI chr10:83,697,174...83,793,676
Ensembl chr10:83,767,206...83,777,183
Ensembl chr10:83,767,206...83,777,183

G

cyclin-dependent kinase 14

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CDK14 mRNA

NCBI chr 4:29,619,237...30,213,651
Ensembl chr 4:29,621,217...30,213,651

G

cyclin-dependent kinase 17

decreases expression

ISO

Folic Acid results in decreased expression of CDK17 mRNA

NCBI chr 7:29,570,982...29,677,613
Ensembl chr 7:29,570,816...29,652,008

G

cyclin-dependent kinase 18

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CDK18 mRNA

NCBI chr13:46,107,763...46,140,705
Ensembl chr13:46,108,911...46,140,865

G

cyclin-dependent kinase 19

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CDK19 mRNA

NCBI chr20:45,324,911...45,465,121
Ensembl chr20:45,324,862...45,465,121

G

cyclin dependent kinase 2

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CDK2 gene
Folic Acid results in decreased expression of CDK2 protein

PMID:20938992 PMID:26056802

NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878

G

cyclin-dependent kinase 20

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CDK20 gene

NCBI chr17:706,863...717,828
Ensembl chr17:706,865...713,567

G

cyclin-dependent kinase 2 associated protein 1

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of CDK2AP1 mRNA
Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CDK2AP1 mRNA]

PMID:22206623 PMID:25629700

NCBI chr12:37,910,718...37,919,446
Ensembl chr12:37,910,718...37,919,446

G

cyclin-dependent kinase 2 associated protein 2

decreases expression

ISO

Folic Acid results in decreased expression of CDK2AP2 mRNA

NCBI chr 1:210,819,155...210,822,604
Ensembl chr 1:210,820,507...210,823,010

G

cyclin-dependent kinase 4

multiple interactions

ISO

Folic Acid affects the reaction [Benzo(a)pyrene results in increased expression of CDK4 protein]
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CDK4 mRNA; Folic Acid inhibits the reaction [sodium arsenite results in decreased phosphorylation of CDK4 protein]

PMID:22206623 PMID:30020114 PMID:39720976

NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163

G

cyclin-dependent kinase 5

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CDK5 mRNA]

NCBI chr 4:11,647,098...11,651,606
Ensembl chr 4:11,647,141...11,652,777

G

cyclin-dependent kinase 5 regulatory subunit 2

decreases expression

ISO

Folic Acid results in decreased expression of CDK5R2 mRNA

NCBI chr 9:83,864,922...83,866,390
Ensembl chr 9:83,864,726...83,867,618

G

cyclin-dependent kinase 6

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CDK6 gene; Folic Acid inhibits the reaction [sodium arsenite results in decreased phosphorylation of CDK6 protein]

PMID:20938992 PMID:39720976

NCBI chr 4:31,592,384...31,784,732
Ensembl chr 4:31,601,192...31,781,701

G

cyclin-dependent kinase 8

decreases expression

ISO

Folic Acid results in decreased expression of CDK8 mRNA

NCBI chr12:13,851,024...13,919,017
Ensembl chr12:13,851,024...13,917,992

G

cyclin-dependent kinase 9

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of CDK9 mRNA
Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CDK9 mRNA]

PMID:22206623 PMID:25629700

NCBI chr 3:36,394,168...36,399,016
Ensembl chr 3:36,394,169...36,399,528

G

CDK5 regulatory subunit associated protein 1-like 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CDKAL1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CDKAL1 gene

PMID:20938992 PMID:22206623

NCBI chr17:34,927,221...35,479,827
Ensembl chr17:34,950,157...35,479,905

G

cyclin dependent kinase like 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CDKL2 gene

NCBI chr14:16,312,154...16,347,524
Ensembl chr14:16,312,932...16,347,523

G

cyclin-dependent kinase-like 3

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CDKL3 mRNA

NCBI chr10:36,755,413...36,850,197
Ensembl chr10:36,764,377...36,878,660

G

cyclin-dependent kinase inhibitor 1A

affects expression
increases expression
multiple interactions

ISO

Folic Acid affects the expression of CDKN1A mRNA; Folic Acid affects the expression of CDKN1A protein
Folic Acid results in increased expression of CDKN1A protein
AG 1879 inhibits the reaction [Folic Acid results in increased expression of CDKN1A protein]; caffeic acid phenethyl ester inhibits the reaction [Folic Acid results in increased expression of CDKN1A protein]; Folic Acid inhibits the reaction [Methotrexate results in increased expression of CDKN1A mRNA]; FOLR1 protein affects the reaction [Folic Acid results in increased expression of CDKN1A protein]; TP53 protein affects the reaction [Folic Acid results in increased expression of CDKN1A protein]; U 0126 inhibits the reaction [Folic Acid results in increased expression of CDKN1A protein]
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CDKN1A mRNA; [Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of CDKN1A mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CDKN1A mRNA; Folic Acid inhibits the reaction [sodium arsenite results in increased expression of CDKN1A protein]; Sorafenib promotes the reaction [Folic Acid inhibits the reaction [sodium arsenite results in increased expression of CDKN1A protein]]

PMID:16361273 PMID:20938992 PMID:22183962 PMID:22206623 PMID:26056802 More...

NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969

G

cyclin-dependent kinase inhibitor 1B

affects expression
multiple interactions
increases expression

ISO

Folic Acid affects the expression of CDKN1B mRNA
AG 1879 inhibits the reaction [Folic Acid results in increased expression of CDKN1B protein]; caffeic acid phenethyl ester inhibits the reaction [Folic Acid results in increased expression of CDKN1B protein]; FOLR1 protein affects the reaction [Folic Acid results in increased expression of CDKN1B protein]; TP53 protein affects the reaction [Folic Acid results in increased expression of CDKN1B protein]; U 0126 inhibits the reaction [Folic Acid results in increased expression of CDKN1B protein]
[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CDKN1B gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CDKN1B mRNA]

PMID:16361273 PMID:20938992 PMID:22206623 PMID:26056802

NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498

G

cyclin-dependent kinase inhibitor 1C

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CDKN1C mRNA

NCBI chr 1:208,084,801...208,087,680
Ensembl chr 1:208,084,787...208,087,498

G

cyclin-dependent kinase inhibitor 2A

affects methylation
multiple interactions
affects expression

ISO

Folic Acid affects the methylation of CDKN2A promoter
MTHFR gene polymorphism affects the reaction [Folic Acid affects the methylation of CDKN2A promoter]
Folic Acid affects the expression of CDKN2A mRNA

PMID:16646054 PMID:17585020

NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:109,100,772...109,119,248

G

cyclin-dependent kinase inhibitor 2B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CDKN2B mRNA

NCBI chr 5:109,123,308...109,134,906
Ensembl chr 5:109,114,322...109,134,855

G

cyclin-dependent kinase inhibitor 2C

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CDKN2C mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CDKN2C mRNA
Folic Acid results in decreased expression of CDKN2C mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr 5:129,639,736...129,645,564
Ensembl chr 5:129,639,736...129,644,891

G

cyclin-dependent kinase inhibitor 3

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CDKN3 mRNA
[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of CDKN3 mRNA

PMID:20938992 PMID:24657277

NCBI chr15:22,502,299...22,513,725
Ensembl chr15:22,502,382...22,513,722

G

cysteine dioxygenase type 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CDO1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CDO1 gene

PMID:20938992 PMID:22206623

NCBI chr18:41,619,076...41,633,719
Ensembl chr18:41,619,070...41,633,891

G

cysteine rich, DPF motif domain containing 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CDPF1 mRNA

NCBI chr 7:118,773,497...118,785,283
Ensembl chr 7:118,780,845...118,783,161

G

cerebellar degeneration-related protein 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CDR2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CDR2 gene

NCBI chr 1:184,934,128...184,959,036
Ensembl chr 1:184,934,129...184,968,863

G

cerebellar degeneration-related protein 2-like

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CDR2L mRNA]

NCBI chr10:101,123,777...101,137,634
Ensembl chr10:101,123,777...101,137,634

G

CDP-diacylglycerol synthase 2

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CDS2 mRNA
Folic Acid results in decreased expression of CDS2 mRNA

PMID:20938992 PMID:25629700

NCBI chr 3:139,967,870...140,006,459
Ensembl chr 3:139,967,742...140,009,201

G

chromatin licensing and DNA replication factor 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CDT1 mRNA

NCBI chr19:67,529,249...67,534,195
Ensembl chr19:67,529,201...67,534,194

G

caudal type homeo box 1

multiple interactions
increases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CDX1 mRNA
Folic Acid results in increased expression of CDX1 mRNA

PMID:22206623 PMID:34742744

NCBI chr18:56,742,970...56,761,299
Ensembl chr18:56,742,984...56,761,299

G

caudal type homeo box 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CDX2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CDX2 gene

PMID:20938992 PMID:22206623

NCBI chr12:12,762,769...12,769,246
Ensembl chr12:12,762,904...12,769,246

G

chromodomain Y-like

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CDYL gene

NCBI chr17:29,188,697...29,409,805
Ensembl chr17:29,188,698...29,409,757

G

chromodomain Y-like 2

decreases expression

ISO

Folic Acid results in decreased expression of CDYL2 mRNA

NCBI chr19:61,500,702...61,691,746
Ensembl chr19:61,500,702...61,691,746

G

CEA cell adhesion molecule 1

multiple interactions

ISO

[Folic Acid deficiency co-treated with Methotrexate] results in increased expression of CEACAM1 mRNA

NCBI chr 1:90,171,401...90,187,810
Ensembl chr 1:90,171,401...90,187,798

G

CCAAT/enhancer binding protein alpha

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CEBPA gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CEBPA mRNA]

PMID:20938992 PMID:22206623

NCBI chr 1:96,896,584...96,899,256
Ensembl chr 1:96,896,171...96,899,309

G

CCAAT/enhancer binding protein beta

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CEBPB mRNA; [[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of MIR155 mRNA] which results in decreased expression of CEBPB protein; [Choline deficiency co-treated with Folic Acid deficiency] inhibits the reaction [CEBPB protein binds to AHCY promoter]; [Choline deficiency co-treated with Folic Acid deficiency] inhibits the reaction [CEBPB protein binds to MAT1A promoter]; [Choline deficiency co-treated with Folic Acid deficiency] inhibits the reaction [CEBPB protein binds to MTHFD1 promoter]; [Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CEBPB protein; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CEBPB protein
[Folic Acid deficiency co-treated with Methotrexate] results in increased expression of CEBPB mRNA

PMID:20548288 PMID:22206623 PMID:23439872 PMID:24657277

NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:176,816,859...176,838,072

G

CCAAT/enhancer binding protein delta

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CEBPD mRNA

NCBI chr11:98,268,856...98,269,994
Ensembl chr11:98,265,651...98,280,824

G

CCAAT/enhancer binding protein zeta

decreases expression

ISO

Folic Acid results in decreased expression of CEBPZ mRNA

NCBI chr 6:21,872,071...21,889,755
Ensembl chr 6:21,872,025...21,889,749

G

CEBPZ opposite strand

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CEBPZOS mRNA

NCBI chr 6:21,887,701...21,892,298
Ensembl chr 6:21,887,709...21,892,074

G

CECR2, histone acetyl-lysine reader

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CECR2 mRNA

NCBI chr 4:155,562,576...155,670,253
Ensembl chr 4:155,562,727...155,666,741

G

carboxyl ester lipase

decreases expression

ISO

Folic Acid results in decreased expression of CEL mRNA

NCBI chr 3:32,281,518...32,289,019
Ensembl chr 3:32,281,518...32,289,019

G

chymotrypsin like elastase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CELA1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CELA1 mRNA

PMID:20938992 PMID:22206623

NCBI chr 7:133,651,939...133,665,136
Ensembl chr 7:133,651,941...133,665,061

G

CUGBP, Elav-like family member 1

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of CELF1 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CELF1 mRNA

PMID:22206623 PMID:25629700

NCBI chr 3:97,380,407...97,455,253
Ensembl chr 3:97,380,424...97,452,791

G

CUGBP, Elav-like family member 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CELF2 mRNA

NCBI chr17:75,813,928...76,639,300
Ensembl chr17:75,813,704...76,636,362

G

CUGBP, Elav-like family member 3

increases expression

ISO

Folic Acid results in increased expression of CELF3 mRNA

NCBI chr 2:184,805,078...184,819,189
Ensembl chr 2:184,805,081...184,819,187

G

CUGBP, Elav-like family member 4

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CELF4 gene

NCBI chr18:17,061,284...17,339,747
Ensembl chr18:17,061,293...17,339,571

G

CUGBP, Elav-like family member 5

decreases expression

ISO

Folic Acid results in decreased expression of CELF5 mRNA

NCBI chr 7:8,876,551...8,901,078
Ensembl chr 7:8,876,564...8,901,069

G

CUGBP, Elav-like family member 6

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CELF6 gene

NCBI chr 8:68,870,902...68,901,863
Ensembl chr 8:68,871,093...68,901,863

G

cadherin, EGF LAG seven-pass G-type receptor 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CELSR1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CELSR1 gene

PMID:20938992 PMID:22206623

NCBI chr 7:118,867,450...119,004,859
Ensembl chr 7:118,867,450...119,004,856

G

cadherin, EGF LAG seven-pass G-type receptor 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CELSR2 gene

NCBI chr 2:198,717,333...198,741,689
Ensembl chr 2:198,717,896...198,741,581

G

cadherin, EGF LAG seven-pass G-type receptor 3

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CELSR3 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of and results in decreased expression of CELSR3; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CELSR3 gene

NCBI chr 8:118,409,136...118,438,593
Ensembl chr 8:118,409,136...118,436,847

G

cell migration inducing hyaluronidase 2

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CEMIP2 gene
Folic Acid results in decreased expression of CEMIP2 mRNA

PMID:20938992 PMID:21867686 PMID:25629700

NCBI chr 1:228,756,826...228,834,313
Ensembl chr 1:228,757,466...228,832,906

G

centromere protein A

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CENPA gene

NCBI chr 6:31,420,062...31,431,703

G

centromere protein B

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CENPB mRNA]

NCBI chr 3:138,850,003...138,852,796
Ensembl chr 3:138,841,679...138,854,372

G

centromere protein C

decreases expression

ISO

Folic Acid results in decreased expression of CENPC1 mRNA

NCBI chr14:22,342,910...22,401,522
Ensembl chr14:22,342,927...22,438,590

G

centromere protein E

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CENPE mRNA

NCBI chr 2:226,310,970...226,369,636
Ensembl chr 2:226,300,798...226,369,636

G

centromere protein F

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CENPF mRNA
[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of CENPF mRNA

PMID:20938992 PMID:24657277

NCBI chr13:103,715,344...103,760,931
Ensembl chr13:103,715,344...103,760,886

G

centromere protein H

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CENPH mRNA

NCBI chr 2:33,630,738...33,644,258
Ensembl chr 2:33,630,738...33,644,242

G

centromere protein I

multiple interactions
decreases expression

ISO

[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of CENPI mRNA
Folic Acid results in decreased expression of CENPI mRNA

PMID:21867686 PMID:24657277

NCBI chr X:101,809,192...101,860,935
Ensembl chr X:101,809,659...101,860,934

G

centromere protein K

multiple interactions
decreases expression

ISO

[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of CENPK mRNA
Folic Acid results in decreased expression of CENPK mRNA

PMID:24657277 PMID:25629700

NCBI chr 2:37,094,163...37,155,158
Ensembl chr 2:37,094,248...37,119,488

G

centromere protein N

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CENPN gene

NCBI chr19:61,880,101...61,902,850
Ensembl chr19:61,877,148...61,902,918

G

centromere protein Q

decreases expression

ISO

Folic Acid results in decreased expression of CENPQ mRNA

NCBI chr 9:27,454,339...27,469,371
Ensembl chr 9:27,454,252...27,469,366

G

centromere protein T

decreases expression

ISO

Folic Acid results in decreased expression of CENPT mRNA

NCBI chr19:50,644,548...50,651,048
Ensembl chr19:50,634,368...50,651,037

G

centromere protein X

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CENPX mRNA

NCBI chr10:106,489,796...106,492,637
Ensembl chr10:106,489,796...106,492,637

G

centrosomal protein 104

decreases expression

ISO

Folic Acid results in decreased expression of CEP104 mRNA

NCBI chr 5:169,817,383...169,849,681
Ensembl chr 5:169,817,182...169,852,695

G

centrosomal protein 112

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CEP112 mRNA

NCBI chr10:93,865,630...94,332,679
Ensembl chr10:93,865,699...94,332,680

G

centrosomal protein 120

decreases expression

ISO

Folic Acid results in decreased expression of CEP120 mRNA

NCBI chr18:49,326,266...49,388,380
Ensembl chr18:49,326,266...49,388,243

G

centrosomal protein 126

decreases expression

ISO

Folic Acid results in decreased expression of CEP126 mRNA

NCBI chr 8:13,485,211...13,552,711
Ensembl chr 8:13,490,685...13,552,221

G

centrosomal protein 135

decreases expression

ISO

Folic Acid results in decreased expression of CEP135 mRNA

NCBI chr14:31,884,774...31,950,050
Ensembl chr14:31,884,781...31,950,050

G

centrosomal protein 164

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CEP164 mRNA
Folic Acid results in decreased expression of CEP164 mRNA

PMID:22206623 PMID:25629700

NCBI chr 8:54,967,621...55,031,264
Ensembl chr 8:54,967,621...55,031,206

G

centrosomal protein 170

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CEP170 mRNA
Folic Acid results in decreased expression of CEP170 mRNA

PMID:20938992 PMID:25629700

NCBI chr13:91,201,808...91,285,990
Ensembl chr13:91,201,808...91,285,990

G

centrosomal protein 170B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CEP170B mRNA

NCBI chr 6:137,602,707...137,627,750
Ensembl chr 6:137,602,707...137,627,750

G

centrosomal protein 19

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CEP19 mRNA

NCBI chr11:82,182,868...82,192,134
Ensembl chr11:82,182,868...82,192,032

G

centrosomal protein 192

decreases expression

ISO

Folic Acid results in decreased expression of CEP192 mRNA

NCBI chr18:63,643,816...63,728,264
Ensembl chr18:63,646,163...63,728,264

G

centrosomal protein 250

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CEP250 mRNA

NCBI chr 3:164,931,033...164,976,210
Ensembl chr 3:164,931,066...164,976,210

G

centrosomal protein 350

decreases expression

ISO

Folic Acid results in decreased expression of CEP350 mRNA

NCBI chr13:70,573,597...70,714,673
Ensembl chr13:70,573,597...70,714,673

G

centrosomal protein 41

decreases expression

ISO

Folic Acid results in decreased expression of CEP41 mRNA

NCBI chr 4:60,238,602...60,279,670
Ensembl chr 4:60,239,539...60,254,419

G

centrosomal protein 43

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CEP43 mRNA

NCBI chr 1:55,080,983...55,111,509
Ensembl chr 1:55,082,712...55,111,509

G

centrosomal protein 44

decreases expression

ISO

Folic Acid results in decreased expression of CEP44 mRNA

NCBI chr16:38,722,259...38,741,603
Ensembl chr16:38,721,513...38,741,614

G

centrosomal protein 55

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CEP55 mRNA
Folic Acid results in increased expression of CEP55 mRNA

PMID:20938992 PMID:25629700

NCBI chr 1:245,245,272...245,260,835
Ensembl chr 1:245,245,306...245,260,890

G

centrosomal protein 57

decreases expression

ISO

Folic Acid results in decreased expression of CEP57 mRNA

NCBI chr 8:18,951,179...18,971,205
Ensembl chr 8:18,932,808...18,970,890

G

centrosomal protein 63

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of CEP63 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CEP63 mRNA

PMID:22206623 PMID:25629700

NCBI chr 8:112,041,586...112,093,061
Ensembl chr 8:112,041,594...112,084,646

G

centrosomal protein 68

decreases expression

ISO

Folic Acid results in decreased expression of CEP68 mRNA

NCBI chr14:98,649,993...98,671,892
Ensembl chr14:98,649,993...98,671,868

G

centrosomal protein 83

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CEP83 mRNA

NCBI chr 7:31,167,198...31,276,513
Ensembl chr 7:31,167,216...31,276,716

G

centrosomal protein 89

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CEP89 mRNA

NCBI chr 1:97,195,116...97,237,015
Ensembl chr 1:97,195,135...97,237,016

G

centrosomal protein 95

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CEP95 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CEP95 gene

PMID:20938992 PMID:22206623

NCBI chr10:92,231,829...92,259,813
Ensembl chr10:92,231,512...92,259,810

G

CERK like autophagy regulator

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CERKL gene

NCBI chr 3:84,641,121...84,747,999
Ensembl chr 3:84,645,696...84,747,688

G

ceramide synthase 2

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of LASS2 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CERS2 mRNA

PMID:22206623 PMID:25629700

NCBI chr 2:185,579,511...185,587,789
Ensembl chr 2:185,579,119...185,588,839

G

ceramide synthase 4

increases expression

ISO

Folic Acid results in increased expression of CERS4 mRNA

NCBI chr12:7,649,610...7,688,066
Ensembl chr12:7,649,610...7,688,070

G

ceramide synthase 5

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CERS5 gene

NCBI chr 7:132,738,834...132,776,920
Ensembl chr 7:132,738,834...132,776,786

G

ceramide transporter 1

decreases expression

ISO

Folic Acid results in decreased expression of CERT1 mRNA

NCBI chr 2:29,617,202...29,721,734
Ensembl chr 2:29,617,023...29,721,729

G

carboxylesterase 2C

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of CES2C mRNA

NCBI chr 1:270,377,201...270,384,768
Ensembl chr 1:270,374,913...270,384,801

G

carboxylesterase 2E

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CES2E mRNA

NCBI chr19:163,899...179,274
Ensembl chr19:163,859...179,308

G

centrin 1

decreases expression

ISO

Folic Acid results in decreased expression of CETN1 mRNA

NCBI chr18:924,428...925,130
Ensembl chr18:922,112...925,332

G

centrin 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CETN2 mRNA

NCBI chr X:155,812,212...155,817,186
Ensembl chr X:155,812,003...155,817,744

G

centrin 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CETN3 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CETN3 gene

PMID:20938992 PMID:22206623

NCBI chr 2:13,817,760...13,837,502
Ensembl chr 2:13,824,803...13,837,502

G

cilia and flagella associated protein 184

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CCDC96 gene

NCBI chr14:78,501,256...78,503,715
Ensembl chr14:78,486,414...78,507,808

G

cilia and flagella associated protein 20

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CFAP20 mRNA

NCBI chr19:9,614,265...9,628,612
Ensembl chr19:9,614,721...9,628,612

G

cilia and flagella associated protein 210

increases expression

ISO

Folic Acid results in increased expression of CFAP210 mRNA

NCBI chr 3:74,928,368...74,962,508
Ensembl chr 3:74,927,880...74,962,497

G

cilia and flagella associated protein 251

decreases expression

ISO

Folic Acid results in decreased expression of CFAP251 mRNA

NCBI chr12:38,923,154...38,997,881
Ensembl chr12:38,922,330...38,954,783

G

cilia and flagella associated protein 263

decreases expression

ISO

Folic Acid results in decreased expression of CFAP263 mRNA

NCBI chr19:9,503,062...9,522,957
Ensembl chr19:9,503,066...9,522,957

G

cilia and flagella associated protein 298

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CFAP298 mRNA

NCBI chr11:43,667,996...43,678,049
Ensembl chr11:43,668,014...43,677,382

G

cilia and flagella associated protein 418

decreases expression

ISO

Folic Acid results in decreased expression of CFAP418 mRNA

NCBI chr 5:28,789,580...28,812,891
Ensembl chr 5:28,792,692...28,812,887

G

cilia and flagella associated protein 46

decreases expression

ISO

Folic Acid results in decreased expression of CFAP46 mRNA

NCBI chr 1:203,832,818...203,912,389
Ensembl chr 1:203,832,522...203,912,587

G

cilia and flagella associated protein 69

decreases expression

ISO

Folic Acid results in decreased expression of CFAP69 mRNA

NCBI chr 4:29,334,624...29,405,513
Ensembl chr 4:29,334,415...29,408,727

G

complement factor B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CFB mRNA

NCBI chr20:3,975,271...3,981,138
Ensembl chr20:3,955,776...3,981,740

G

craniofacial development protein 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CFDP1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CFDP1 gene

PMID:20938992 PMID:22206623

NCBI chr19:56,627,596...56,733,099
Ensembl chr19:56,626,963...56,733,098

G

complement factor H-related 1

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of CFHR2 mRNA
Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CFHR2 mRNA]

PMID:22206623 PMID:25629700

NCBI chr13:53,946,298...53,961,282
Ensembl chr13:53,919,927...53,961,303

G

cofilin 1

affects expression
decreases expression

EXP
ISO

Folic Acid affects the expression of CFL1 protein
Folic Acid results in decreased expression of CFL1 mRNA

PMID:16251605 PMID:25629700

NCBI chr 1:212,227,124...212,230,656
Ensembl chr 1:212,226,121...212,231,353

G

cofilin 2

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CFL2 mRNA]

NCBI chr 6:78,090,843...78,094,888
Ensembl chr 6:78,090,843...78,094,888

G

CASP8 and FADD-like apoptosis regulator

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CFLAR gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CFLAR mRNA]

PMID:20938992 PMID:22206623

NCBI chr 9:67,679,502...67,747,226
Ensembl chr 9:67,679,559...67,726,434

G

CF transmembrane conductance regulator

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CFTR mRNA

NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643

G

CGG triplet repeat binding protein 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CGGBP1 gene
Folic Acid results in decreased expression of CGGBP1 mRNA

PMID:20938992 PMID:25629700

NCBI chr11:16,012,251...16,019,388
Ensembl chr11:16,011,456...16,020,356

G

cingulin-like 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CGNL1 mRNA

NCBI chr 8:81,154,169...81,305,598
Ensembl chr 8:81,140,091...81,305,747

G

cell growth regulator with EF hand domain 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CGREF1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CGREF1 mRNA

PMID:20938992 PMID:22206623

NCBI chr 6:31,151,795...31,163,801
Ensembl chr 6:31,151,795...31,163,800

G

ChaC glutathione-specific gamma-glutamylcyclotransferase 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CHAC1 gene

NCBI chr 3:126,796,131...126,799,352
Ensembl chr 3:126,796,024...126,799,361

G

ChaC glutathione specific gamma-glutamylcyclotransferase 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CHAC2 mRNA

NCBI chr14:108,921,669...108,929,215
Ensembl chr14:108,921,341...108,929,469

G

chromatin assembly factor 1 subunit A

decreases expression

ISO

Folic Acid results in decreased expression of CHAF1A mRNA

NCBI chr 9:961,225...987,825
Ensembl chr 9:961,084...987,868

G

chromatin assembly factor 1 subunit B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CHAF1B mRNA

NCBI chr11:46,670,560...46,690,739
Ensembl chr11:46,670,630...46,690,733

G

chromosome alignment maintaining phosphoprotein 1

decreases expression

ISO

Folic Acid results in decreased expression of CHAMP1 mRNA

NCBI chr16:82,436,172...82,447,144
Ensembl chr16:82,434,823...82,458,984

G

coiled-coil-helix-coiled-coil-helix domain containing 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CHCHD1 mRNA

NCBI chr15:3,641,973...3,643,155
Ensembl chr15:3,641,981...3,643,155

G

coiled-coil-helix-coiled-coil-helix domain containing 10

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CHCHD10 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CHCHD10 gene

PMID:20938992 PMID:22206623

NCBI chr20:12,725,274...12,730,295
Ensembl chr20:12,725,277...12,745,677

G

coiled-coil-helix-coiled-coil-helix domain containing 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CHCHD2 mRNA

NCBI chr12:32,464,847...32,470,871
Ensembl chr12:32,464,824...32,470,871

G

coiled-coil-helix-coiled-coil-helix domain containing 3

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CHCHD3 mRNA
Folic Acid results in decreased expression of CHCHD3 mRNA

PMID:22206623 PMID:25629700

NCBI chr 4:62,327,574...62,584,085
Ensembl chr 4:62,327,576...62,584,035

G

coiled-coil-helix-coiled-coil-helix domain containing 4

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CHCHD4 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CHCHD4 gene

PMID:20938992 PMID:22206623

NCBI chr 4:125,525,428...125,534,562
Ensembl chr 4:125,525,429...125,534,562
Ensembl chr 1:125,525,429...125,534,562

G

coiled-coil-helix-coiled-coil-helix domain containing 5

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CHCHD5 mRNA
Folic Acid results in decreased expression of CHCHD5 mRNA

PMID:22206623 PMID:25629700

NCBI chr 3:136,815,034...136,819,230
Ensembl chr 3:136,815,048...136,821,914

G

coiled-coil-helix-coiled-coil-helix domain containing 6

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CHCHD6 mRNA

NCBI chr 4:123,360,729...123,581,429
Ensembl chr 4:123,349,187...123,581,421

G

coiled-coil-helix-coiled-coil-helix domain containing 7

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CHCHD7 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CHCHD7 gene
Folic Acid results in decreased expression of CHCHD7 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr 5:21,754,719...21,759,274
Ensembl chr 5:21,754,719...21,759,274

G

chromodomain helicase DNA binding protein 1-like

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CHD1L mRNA

NCBI chr 2:187,819,869...187,906,359
Ensembl chr 2:187,811,954...187,890,477

G

chromodomain helicase DNA binding protein 2

decreases expression

ISO

Folic Acid results in decreased expression of CHD2 mRNA

NCBI chr 1:136,597,993...136,726,874
Ensembl chr 1:136,599,900...136,710,335

G

chromodomain helicase DNA binding protein 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CHD3 mRNA

NCBI chr10:54,562,437...54,588,842
Ensembl chr10:54,562,437...54,588,810

G

chromodomain helicase DNA binding protein 6

decreases expression

ISO

Folic Acid results in decreased expression of CHD6 mRNA

NCBI chr 3:170,016,204...170,177,480
Ensembl chr 3:170,016,204...170,177,558

G

chromodomain helicase DNA binding protein 9

decreases expression

ISO

Folic Acid results in decreased expression of CHD9 mRNA

NCBI chr19:32,114,379...32,337,488
Ensembl chr19:32,115,920...32,319,042

G

checkpoint kinase 1

affects expression
multiple interactions

ISO

Folic Acid affects the expression of CHEK1 mRNA
[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CHEK1 mRNA

PMID:16361273 PMID:20938992

NCBI chr 8:44,609,417...44,629,867
Ensembl chr 8:44,609,417...44,629,359

G

checkpoint kinase 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CHEK2 gene

NCBI chr12:51,448,838...51,481,159
Ensembl chr12:51,449,140...51,480,667

G

calcium homeostasis endoplasmic reticulum protein

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CHERP mRNA

NCBI chr16:17,401,497...17,414,549
Ensembl chr16:17,401,497...17,414,549

G

checkpoint with forkhead and ring finger domains

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CHFR mRNA

NCBI chr12:52,164,214...52,197,860
Ensembl chr12:52,164,217...52,197,703

G

chromogranin A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CHGA mRNA

NCBI chr 6:127,460,895...127,472,238
Ensembl chr 6:127,460,854...127,472,237

G

chromogranin B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CHGB mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CHGB mRNA

PMID:20938992 PMID:22206623

NCBI chr 3:140,496,712...140,510,057
Ensembl chr 3:140,495,951...140,510,054

G

cysteine-rich hydrophobic domain 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CHIC1 mRNA

NCBI chr X:72,427,851...72,471,924
Ensembl chr X:72,427,851...72,471,924

G

cysteine-rich hydrophobic domain 2

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of CHIC2 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CHIC2 mRNA

PMID:22206623 PMID:25629700

NCBI chr14:33,511,839...33,546,181
Ensembl chr14:33,511,535...33,548,558

G

choline kinase alpha

multiple interactions
decreases expression

ISO

[Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of CHKA mRNA
Folic Acid results in decreased expression of CHKA mRNA

PMID:25629700 PMID:29127188

NCBI chr 1:210,506,069...210,554,753
Ensembl chr 1:210,506,056...210,554,752

G

cell adhesion molecule L1-like

increases expression

ISO

Folic Acid results in increased expression of CHL1 mRNA

NCBI chr 4:137,847,648...138,062,077
Ensembl chr 4:137,847,895...138,062,077

G

charged multivesicular body protein 1A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CHMP1A mRNA

NCBI chr19:68,146,672...68,154,952
Ensembl chr19:68,146,672...68,154,952

G

charged multivesicular body protein 1B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CHMP1B mRNA

NCBI chr18:63,010,270...63,012,800
Ensembl chr18:63,010,251...63,011,415

G

charged multivesicular body protein 2A

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CHMP2A mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CHMP2A gene
Folic Acid results in decreased expression of CHMP2A mRNA

PMID:20938992 PMID:21867686 PMID:22206623

NCBI chr 1:82,731,212...82,735,088
Ensembl chr 1:82,732,231...82,738,613

G

charged multivesicular body protein 2B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CHMP2B mRNA

NCBI chr11:16,783,971...16,810,500
Ensembl chr11:16,783,971...16,828,868

G

charged multivesicular body protein 3

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of VPS24 gene

NCBI chr 4:105,134,860...105,180,862
Ensembl chr 4:105,134,755...105,182,262

G

charged multivesicular body protein 4B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CHMP4B mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CHMP4B gene

PMID:20938992 PMID:22206623

NCBI chr 3:163,631,054...163,671,569
Ensembl chr 3:163,631,054...163,671,569

G

charged multivesicular body protein 4C

increases expression
decreases expression

ISO

Folic Acid results in increased expression of CHMP4C mRNA
Folic Acid results in decreased expression of CHMP4C mRNA

PMID:21867686 PMID:25629700

NCBI chr 2:93,299,152...93,336,075
Ensembl chr 2:93,299,157...93,360,850

G

charged multivesicular body protein 5

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CHMP5 mRNA

NCBI chr 5:60,877,369...60,894,512
Ensembl chr 5:60,877,341...60,894,511

G

charged multivesicular body protein 7

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CHMP7 mRNA

NCBI chr15:51,200,759...51,215,992
Ensembl chr15:51,201,298...51,215,992

G

chimerin 2

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of CHN2 mRNA
[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CHN2 mRNA

PMID:20938992 PMID:25629700

NCBI chr 4:84,478,989...84,738,068
Ensembl chr 4:84,704,862...84,738,068

G

chondrolectin

decreases expression
increases expression

ISO

Folic Acid results in decreased expression of CHODL mRNA
Folic Acid results in increased expression of CHODL mRNA

PMID:21867686 PMID:25629700

NCBI chr11:31,141,030...31,163,342
Ensembl chr11:31,141,021...31,163,334

G

cysteine and histidine rich domain containing 1

decreases expression

ISO

Folic Acid results in decreased expression of CHORDC1 mRNA

NCBI chr 8:23,650,721...23,674,786
Ensembl chr 8:23,650,865...23,677,696

G

calcineurin-like EF-hand protein 1

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CHP1 mRNA]

NCBI chr 3:126,989,800...127,025,071
Ensembl chr 3:126,989,579...127,042,443

G

choline phosphotransferase 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CHPT1 mRNA

NCBI chr 7:24,753,880...24,802,529
Ensembl chr 7:24,750,343...24,802,521

G

chromatin accessibility complex subunit 1

multiple interactions
decreases expression

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CHRAC1 mRNA]
Folic Acid results in decreased expression of CHRAC1 mRNA

PMID:22206623 PMID:25629700

NCBI chr 7:106,901,841...106,905,441

G

chordin-like 1

multiple interactions
decreases expression

ISO

[Ethanol co-treated with Folic Acid] results in decreased expression of CHRDL1 mRNA
Folic Acid results in decreased expression of CHRDL1 mRNA

PMID:23378141 PMID:25629700

NCBI chr X:111,685,864...111,789,684
Ensembl chr X:111,685,866...111,789,661

G

cholinergic receptor, muscarinic 4

decreases expression
increases expression

ISO

Folic Acid results in decreased expression of CHRM4 mRNA
Folic Acid results in increased expression of CHRM4 mRNA

PMID:25006883 PMID:25629700

NCBI chr 3:98,349,080...98,356,821
Ensembl chr 3:98,348,650...98,358,771

G

cholinergic receptor, muscarinic 5

increases expression

ISO

Folic Acid results in increased expression of CHRM5 mRNA

NCBI chr 3:119,739,229...119,791,630
Ensembl chr 3:119,735,975...119,792,166

G

cholinergic receptor nicotinic alpha 2 subunit

decreases expression

ISO

Folic Acid results in decreased expression of CHRNA2 mRNA

NCBI chr15:44,517,862...44,534,144
Ensembl chr15:44,517,862...44,534,144

G

cholinergic receptor nicotinic alpha 3 subunit

decreases expression

ISO

Folic Acid results in decreased expression of CHRNA3 mRNA

NCBI chr 8:64,297,755...64,311,251
Ensembl chr 8:64,297,755...64,311,412

G

cholinergic receptor nicotinic beta 1 subunit

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CHRNB1 mRNA

NCBI chr10:54,999,943...55,015,137
Ensembl chr10:55,002,788...55,015,107

G

cholinergic receptor nicotinic beta 2 subunit

decreases expression

ISO

Folic Acid results in decreased expression of CHRNB2 mRNA

NCBI chr 2:177,479,091...177,487,306
Ensembl chr 2:177,479,091...177,491,326

G

cholinergic receptor nicotinic beta 3 subunit

decreases expression

ISO

Folic Acid results in decreased expression of CHRNB3 mRNA

NCBI chr16:71,411,847...71,454,225
Ensembl chr16:71,417,039...71,454,225

G

cholinergic receptor nicotinic beta 4 subunit

multiple interactions

ISO

[Folic Acid co-treated with Ethanol] results in increased expression of CHRNB4 mRNA

NCBI chr 8:64,312,644...64,333,319
Ensembl chr 8:64,313,669...64,333,248

G

carbohydrate sulfotransferase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CHST1 mRNA

NCBI chr 3:99,003,987...99,030,214
Ensembl chr 3:99,009,958...99,031,262

G

carbohydrate sulfotransferase 11

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CHST11 mRNA
Folic Acid results in decreased expression of CHST11 mRNA

PMID:20938992 PMID:25629700

NCBI chr 7:22,412,121...22,630,577
Ensembl chr 7:22,415,686...22,630,441

G

carbohydrate sulfotransferase 12

decreases expression

ISO

Folic Acid results in decreased expression of CHST12 mRNA

NCBI chr12:19,224,545...19,243,012
Ensembl chr12:19,220,141...19,243,047

G

carbohydrate sulfotransferase 13

increases expression

ISO

Folic Acid results in increased expression of CHST13 mRNA

NCBI chr 4:124,381,226...124,395,143
Ensembl chr 4:124,381,226...124,395,143

G

carbohydrate sulfotransferase 14

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CHST14 mRNA

NCBI chr 3:126,370,348...126,372,405
Ensembl chr 3:126,370,348...126,372,777

G

carbohydrate sulfotransferase 15

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CHST15 mRNA

NCBI chr 1:196,458,978...196,540,088
Ensembl chr 1:196,460,425...196,491,444

G

carbohydrate sulfotransferase 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CHST3 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CHST3 gene

PMID:20938992 PMID:22206623

NCBI chr20:28,657,308...28,694,976
Ensembl chr20:28,657,308...28,694,526

G

carbohydrate sulfotransferase 4

increases expression

ISO

Folic Acid results in increased expression of CHST4 mRNA

NCBI chr19:54,900,914...54,911,735
Ensembl chr19:54,882,719...54,916,648

G

carbohydrate sulfotransferase 6

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CHST5 gene

NCBI chr19:56,769,991...56,790,276
Ensembl chr19:56,769,967...56,790,306

G

carbohydrate sulfotransferase 8

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CHST8 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CHST8 gene

NCBI chr 1:96,431,144...96,572,880
Ensembl chr 1:96,431,145...96,572,880

G

chondroitin sulfate synthase 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CHSY1 gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CHSY1 mRNA]

PMID:20938992 PMID:22206623

NCBI chr 1:129,100,088...129,161,167
Ensembl chr 1:129,100,041...129,161,081

G

chondroitin sulfate synthase 3

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CHSY3 gene

NCBI chr18:54,842,260...55,096,008
Ensembl chr18:54,842,180...55,095,981

G

chromosome transmission fidelity factor 18

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CHTF18 mRNA

NCBI chr10:15,247,525...15,255,573
Ensembl chr10:15,246,362...15,255,685

G

chromosome transmission fidelity factor 8

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CHTF8 mRNA

NCBI chr19:51,691,776...51,702,076
Ensembl chr19:51,678,543...51,707,144

G

chromatin target of PRMT1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CHTOP mRNA

NCBI chr 2:178,278,848...178,291,142
Ensembl chr 2:178,278,848...178,290,348

G

component of inhibitor of nuclear factor kappa B kinase complex

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CHUK mRNA]

NCBI chr 1:252,908,748...252,944,273
Ensembl chr 1:252,908,749...252,944,273

G

churchill domain containing 1

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CHURC1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CHURC1 gene
Folic Acid results in decreased expression of CHURC1 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr 6:101,203,778...101,218,364
Ensembl chr 6:101,203,841...101,237,748

G

cytosolic iron-sulfur assembly component 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CIAO1 mRNA

NCBI chr 3:134,913,639...134,919,244
Ensembl chr 3:134,913,172...134,979,255

G

cytosolic iron-sulfur assembly component 2A

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of FAM96A mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CIAO2A mRNA

PMID:22206623 PMID:25629700

NCBI chr 8:75,565,620...75,577,542
Ensembl chr 8:75,565,567...75,577,541

G

cytosolic iron-sulfur assembly component 2B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CIAO2B mRNA

NCBI chr19:350,644...352,518
Ensembl chr19:350,653...352,518

G

cytosolic iron-sulfur assembly component 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CIAO3 mRNA

NCBI chr10:15,300,403...15,309,467
Ensembl chr10:15,300,471...15,309,468

G

cytokine induced apoptosis inhibitor 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CIAPIN1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CIAPIN1 gene

PMID:20938992 PMID:22206623

NCBI chr19:10,185,955...10,199,120
Ensembl chr19:10,182,088...10,201,495

G

CBY1 interacting BAR domain containing 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CIBAR1 mRNA

NCBI chr 5:30,411,325...30,429,770
Ensembl chr 5:30,410,511...30,429,893

G

cell death-inducing DFFA-like effector a

multiple interactions

ISO

[Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of CIDEA mRNA

NCBI chr18:63,164,817...63,190,384
Ensembl chr18:63,164,099...63,190,382

G

cell death-inducing DFFA-like effector b

affects expression

ISO

Folic Acid affects the expression of CIDEB mRNA

NCBI chr15:33,222,135...33,226,407
Ensembl chr15:33,221,824...33,226,688

G

cell death-inducing DFFA-like effector c

decreases expression

ISO

Folic Acid results in decreased expression of CIDEC mRNA

NCBI chr 4:148,124,924...148,137,806
Ensembl chr 4:148,124,925...148,137,806

G

class II, major histocompatibility complex, transactivator

increases expression

ISO

Folic Acid results in increased expression of CIITA mRNA

NCBI chr10:5,646,854...5,694,393
Ensembl chr10:5,647,085...5,694,342

G

ciliogenesis associated kinase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CILK1 mRNA

NCBI chr 8:87,868,294...87,922,995
Ensembl chr 8:87,868,156...87,922,995

G

cartilage intermediate layer protein

increases expression

ISO

Folic Acid results in increased expression of CILP mRNA

NCBI chr 8:74,671,696...74,687,420
Ensembl chr 8:74,671,534...74,687,409

G

cartilage intermediate layer protein 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CILP2 gene

NCBI chr16:19,573,821...19,581,100
Ensembl chr16:19,573,908...19,581,100

G

ciliary microtubule inner protein 5

increases expression

ISO

Folic Acid results in increased expression of CIMIP5 mRNA

NCBI chr 6:45,520,575...45,525,810
Ensembl chr 6:45,521,891...45,525,810

G

CLOCK-interacting pacemaker

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CIPC mRNA

NCBI chr 6:112,325,980...112,344,692
Ensembl chr 6:112,325,671...112,344,692

G

corepressor interacting with RBPJ, CIR1

decreases expression

ISO

Folic Acid results in decreased expression of CIR1 mRNA

NCBI chr 3:78,566,438...78,596,309
Ensembl chr 3:78,566,438...78,596,309

G

CDGSH iron sulfur domain 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CISD1 mRNA

NCBI chr20:17,254,462...17,267,843
Ensembl chr20:17,254,187...17,271,042

G

CDGSH iron sulfur domain 2

decreases expression

ISO

Folic Acid results in decreased expression of CISD2 mRNA

NCBI chr 2:226,502,517...226,527,325
Ensembl chr 2:226,502,517...226,540,080

G

CDGSH iron sulfur domain 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CISD3 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CISD3 gene

PMID:20938992 PMID:22206623

NCBI chr10:83,175,708...83,178,739
Ensembl chr10:83,175,568...83,178,751

G

cytokine inducible SH2-containing protein

decreases expression

ISO

Folic Acid results in decreased expression of CISH mRNA

NCBI chr 8:116,850,969...116,855,917
Ensembl chr 8:116,850,773...116,855,986

G

citron rho-interacting serine/threonine kinase

multiple interactions

ISO

[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of CIT mRNA

NCBI chr12:46,263,881...46,425,642
Ensembl chr12:46,266,369...46,424,656

G

Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CITED1 gene

NCBI chr X:71,390,328...71,395,023
Ensembl chr X:71,390,331...71,393,649

G

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CITED2 mRNA

NCBI chr 1:14,132,303...14,134,746
Ensembl chr 1:14,103,457...14,134,782

G

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CITED4 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CITED4 mRNA

PMID:20938992 PMID:22206623

NCBI chr 5:139,532,165...139,533,056
Ensembl chr 5:139,531,584...139,533,361

G

cytoskeleton associated protein 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CKAP2 mRNA

NCBI chr16:76,542,114...76,567,297
Ensembl chr16:76,542,104...76,567,352

G

cytoskeleton associated protein 2-like

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CKAP2L mRNA

NCBI chr 3:136,950,390...136,977,503
Ensembl chr 3:136,950,381...136,977,565

G

creatine kinase B

multiple interactions
affects expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CKB mRNA
Folic Acid affects the expression of CKB mRNA

PMID:20938992 PMID:25629700

NCBI chr 6:136,550,583...136,553,464
Ensembl chr 6:136,549,844...136,553,478

G

chemokine-like factor

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CKLF mRNA
Folic Acid results in decreased expression of CKLF mRNA

PMID:20938992 PMID:21867686 PMID:25629700

NCBI chr19:704,528...712,998
Ensembl chr19:697,451...712,998

G

creatine kinase, mitochondrial 1

increases expression

ISO

Folic Acid results in increased expression of CKMT1 mRNA

NCBI chr 3:128,783,408...128,789,485
Ensembl chr 3:128,783,597...128,789,483

G

CDC28 protein kinase regulatory subunit 1B

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CKS1B mRNA]

NCBI chr 2:177,130,751...177,135,333
Ensembl chr 2:177,130,777...177,135,365

G

cytoplasmic linker associated protein 1

decreases expression

ISO

Folic Acid results in decreased expression of CLASP1 mRNA

NCBI chr13:32,046,362...32,267,954
Ensembl chr13:32,046,444...32,267,924

G

CLK4-associating serine/arginine rich protein

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of SFRS16 gene
Folic Acid results in increased expression of CLASRP mRNA

PMID:20938992 PMID:25629700

NCBI chr 1:88,360,235...88,384,343
Ensembl chr 1:88,360,235...88,384,343

G

chloride channel accessory 1

decreases expression

ISO

Folic Acid results in decreased expression of CLCA1 mRNA

NCBI chr 2:236,599,022...236,624,714
Ensembl chr 2:236,599,022...236,624,714

G

chloride channel accessory 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CLCA2 mRNA

NCBI chr 2:236,655,419...236,682,669
Ensembl chr 2:236,639,545...236,685,129

G

cardiotrophin-like cytokine factor 1

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of CLCF1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CLCF1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CLCF1 gene

PMID:20938992 PMID:33549593

NCBI chr 1:210,937,763...210,947,064
Ensembl chr 1:210,937,255...210,947,064

G

chloride voltage-gated channel 2

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CLCN2 mRNA
Folic Acid results in decreased expression of CLCN2 mRNA

PMID:22206623 PMID:25629700

NCBI chr11:93,702,382...93,716,059
Ensembl chr11:93,702,360...93,716,059

G

chloride voltage-gated channel 4

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CLCN4 mRNA

NCBI chr X:27,290,769...27,356,967
Ensembl chr X:27,290,868...27,356,939

G

chloride voltage-gated channel 5

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CLCN5 mRNA
Folic Acid results in decreased expression of CLCN5 mRNA

PMID:20938992 PMID:21867686

NCBI chr X:17,857,260...18,011,844
Ensembl chr X:17,857,260...18,011,844

G

chloride voltage-gated channel 7

decreases expression

ISO

Folic Acid results in decreased expression of CLCN7 mRNA

NCBI chr10:14,656,261...14,681,632
Ensembl chr10:14,656,245...14,681,631

G

claudin 10

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CLDN10 gene
Folic Acid results in decreased expression of CLDN10 mRNA

PMID:20938992 PMID:21867686

NCBI chr15:102,269,858...102,361,589
Ensembl chr15:102,269,858...102,361,589

G

claudin 15

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CLDN15 mRNA

NCBI chr12:25,334,849...25,345,104
Ensembl chr12:25,334,849...25,343,477

G

claudin 2

increases expression

ISO

Folic Acid results in increased expression of CLDN2 mRNA

NCBI chr X:108,248,383...108,258,847
Ensembl chr X:108,237,676...108,262,377

G

claudin 22

increases expression

ISO

Folic Acid results in increased expression of CLDN22 mRNA

NCBI chr16:51,155,058...51,156,084

G

claudin 23

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CLDN23 mRNA

NCBI chr16:63,117,045...63,118,769
Ensembl chr16:63,116,781...63,118,957

G

claudin 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CLDN3 mRNA

NCBI chr12:27,345,075...27,346,547
Ensembl chr12:27,345,076...27,348,841

G

claudin 4

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CLDN4 mRNA

NCBI chr12:27,388,160...27,389,958
Ensembl chr12:27,387,981...27,389,958

G

claudin 6

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CLDN6 gene

NCBI chr10:13,213,837...13,218,578
Ensembl chr10:13,213,956...13,218,581

G

claudin 7

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CLDN7 mRNA
Folic Acid results in decreased expression of CLDN7 mRNA

PMID:20938992 PMID:21867686

NCBI chr10:55,188,670...55,190,871
Ensembl chr10:55,188,684...55,190,905

G

C-type lectin domain containing 10A

decreases expression

ISO

Folic Acid results in decreased expression of CLEC10A mRNA

NCBI chr10:55,374,914...55,379,110
Ensembl chr10:55,374,887...55,379,108

G

C-type lectin domain containing 11A

decreases expression

ISO

Folic Acid results in decreased expression of CLEC11A mRNA

NCBI chr 1:103,938,029...103,941,170
Ensembl chr 1:103,935,185...103,946,784

G

C-type lectin domain family 18, member A

increases expression

ISO

Folic Acid results in increased expression of CLEC18A mRNA

NCBI chr19:55,947,625...55,964,505
Ensembl chr19:55,947,223...55,965,323

G

C-type lectin domain family 4, member A

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CLEC4N mRNA

NCBI chr 4:158,026,138...158,119,904
Ensembl chr 4:158,100,615...158,118,094

G

C-type lectin domain family 4, member A3

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CLEC4A3 mRNA

NCBI chr 4:157,885,899...157,896,728
Ensembl chr 4:157,885,895...157,896,727

G

C-type lectin domain family 4, member B2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CLEC4B1 mRNA

NCBI chr 4:158,148,434...158,171,933
Ensembl chr 4:158,148,314...158,172,249

G

C-type lectin domain family 4, member D

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CLEC4D mRNA

NCBI chr 4:158,275,287...158,286,978
Ensembl chr 4:158,275,341...158,287,055

G

C-type lectin domain family 4 member M

decreases expression

ISO

Folic Acid results in decreased expression of CLEC4M mRNA

NCBI chr12:6,713,795...6,722,414
Ensembl chr12:6,713,812...6,722,410

G

C-type lectin domain containing 5A

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CLEC5A mRNA
Folic Acid results in decreased expression of CLEC5A mRNA

PMID:20938992 PMID:25629700

NCBI chr 4:70,373,855...70,383,560
Ensembl chr 4:70,374,529...70,398,230

G

C-type lectin domain containing 7A

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CLEC7A mRNA

NCBI chr 4:164,588,737...164,599,953
Ensembl chr 4:164,588,754...164,599,919

G

calmegin

increases expression
decreases expression

ISO

Folic Acid results in increased expression of CLGN mRNA
Folic Acid results in decreased expression of CLGN mRNA

PMID:11723236 PMID:25629700

NCBI chr19:41,601,568...41,633,207
Ensembl chr19:41,601,568...41,633,325

G

chloride intracellular channel 1

multiple interactions
increases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CLIC1 mRNA
Folic Acid results in increased expression of CLIC1 mRNA

PMID:22206623 PMID:25629700

NCBI chr20:3,769,522...3,778,367
Ensembl chr20:3,769,527...3,778,367

G

chloride intracellular channel 4

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CLIC4 gene
Folic Acid results in decreased expression of CLIC4 mRNA

PMID:20938992 PMID:25629700

NCBI chr 5:152,737,371...152,797,118
Ensembl chr 5:152,737,371...152,797,118

G

chloride intracellular channel 6

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CLIC6 mRNA

NCBI chr11:45,223,715...45,266,261
Ensembl chr11:45,223,669...45,267,344

G

clathrin interactor 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CLINT1 gene
Folic Acid results in decreased expression of CLINT1 mRNA

PMID:20938992 PMID:25629700

NCBI chr10:30,799,936...30,854,513
Ensembl chr10:30,799,971...30,854,508

G

CAP-GLY domain containing linker protein 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CLIP1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CLIP1 gene

PMID:20938992 PMID:22206623

NCBI chr12:38,571,533...38,678,779
Ensembl chr12:38,571,834...38,678,779

G

CAP-GLY domain containing linker protein 3

multiple interactions
affects expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CLIP3 mRNA
Folic Acid affects the expression of CLIP3 mRNA

PMID:22206623 PMID:25629700

NCBI chr 1:94,674,492...94,690,643
Ensembl chr 1:94,674,661...94,690,642

G

CAP-GLY domain containing linker protein family, member 4

decreases expression

ISO

Folic Acid results in decreased expression of CLIP4 mRNA

NCBI chr 6:29,359,628...29,449,365
NCBI chr 6:29,349,245...29,351,890
Ensembl chr 6:29,348,918...29,449,271

G

CDC-like kinase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CLK1 mRNA

NCBI chr 9:67,441,962...67,453,180
Ensembl chr 9:67,441,952...67,451,187

G

CDC-like kinase 3

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CLK3 mRNA]

NCBI chr 8:67,048,121...67,063,192
Ensembl chr 8:67,048,123...67,062,881

G

CDC-like kinase 4

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CLK4 gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CLK4 mRNA]

PMID:20938992 PMID:22206623

NCBI chr10:36,024,364...36,042,366
Ensembl chr10:36,024,427...36,042,372

G

calmin

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of CLMN mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CLMN mRNA

PMID:22206623 PMID:25629700

NCBI chr 6:129,470,613...129,572,079
Ensembl chr 6:129,478,149...129,572,027

G

CLN3 lysosomal/endosomal transmembrane protein, battenin

decreases expression

ISO

Folic Acid results in decreased expression of CLN3 mRNA

PMID:21867686 PMID:25629700

NCBI chr 1:190,586,649...190,600,034
Ensembl chr 1:190,586,650...190,597,929

G

CLN5, intracellular trafficking protein

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of CLN5 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CLN5 mRNA

PMID:22206623 PMID:25629700

NCBI chr15:86,308,286...86,321,679
Ensembl chr 2:67,620,667...67,622,952
Ensembl chr15:67,620,667...67,622,952

G

CLN6, transmembrane ER protein

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CLN6 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CLN6 mRNA

PMID:20938992 PMID:22206623

NCBI chr 8:72,198,773...72,213,777
Ensembl chr 8:72,198,712...72,213,776

G

chloride nucleotide-sensitive channel 1A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CLNS1A mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CLNS1A gene

PMID:20938992 PMID:22206623

NCBI chr 1:161,429,437...161,450,904
Ensembl chr 1:161,421,808...161,450,902

G

clock circadian regulator

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CLOCK mRNA

NCBI chr14:32,262,747...32,346,872
Ensembl chr14:32,262,750...32,346,872

G

ClpB family mitochondrial disaggregase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CLPB mRNA

NCBI chr 1:165,440,705...165,563,514
Ensembl chr 1:165,440,861...165,583,815

G

caseinolytic mitochondrial matrix peptidase proteolytic subunit

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CLPP mRNA

NCBI chr 9:1,917,305...1,924,706
Ensembl chr 9:1,918,682...1,924,705

G

colipase

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of CLPS mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CLPS mRNA

PMID:22206623 PMID:25629700

NCBI chr20:6,622,234...6,624,414
Ensembl chr20:6,622,231...6,624,505

G

CLPTM1 regulator of GABA type A receptor forward trafficking

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CLPTM1 mRNA

NCBI chr 1:88,417,447...88,449,047
Ensembl chr 1:88,417,447...88,449,446

G

CLPTM1-like

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CLPTM1L mRNA

NCBI chr 1:31,496,094...31,512,148
Ensembl chr 1:31,496,094...31,512,077

G

caseinolytic mitochondrial matrix peptidase chaperone subunit X

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CLPX mRNA
Folic Acid results in decreased expression of CLPX mRNA

PMID:22206623 PMID:25629700

NCBI chr 8:74,700,602...74,740,244
Ensembl chr 8:74,700,662...74,744,762

G

calsyntenin 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CLSTN1 mRNA

NCBI chr 5:165,314,128...165,377,627
Ensembl chr 5:165,314,309...165,377,625

G

clathrin, light chain A

increases expression
multiple interactions

ISO

Folic Acid results in increased expression of CLTA mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CLTA mRNA

PMID:22206623 PMID:25629700

NCBI chr 5:63,022,046...63,059,223
Ensembl chr 5:63,041,184...63,059,215

G

clathrin, light chain B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CLTB mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CLTB mRNA

PMID:20938992 PMID:22206623

NCBI chr17:10,006,416...10,024,278
Ensembl chr17:10,006,656...10,024,915

G

clathrin heavy chain

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CLTC mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CLTC gene

PMID:20938992 PMID:22206623

NCBI chr10:72,014,984...72,073,308
Ensembl chr10:72,014,986...72,070,691

G

clusterin

increases expression
multiple interactions

EXP
ISO

Folic Acid results in increased expression of CLU mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CLU mRNA

PMID:1482756 PMID:22206623 PMID:25629700

NCBI chr15:44,336,619...44,375,861
Ensembl chr15:44,359,914...44,375,860

G

clustered mitochondria homolog

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CLUH mRNA

NCBI chr10:60,008,052...60,029,742
Ensembl chr10:60,008,119...60,029,742

G

clavesin 2

decreases expression

ISO

Folic Acid results in decreased expression of CLVS2 mRNA

NCBI chr 1:25,553,981...25,661,806
Ensembl chr 1:25,554,375...25,580,830

G

calaxin

decreases expression

ISO

Folic Acid results in decreased expression of CLXN mRNA

NCBI chr11:99,410,925...99,500,713
Ensembl chr11:99,487,448...99,500,760

G

citramalyl-CoA lyase

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CLYBL gene
Folic Acid results in decreased expression of CLYBL mRNA

PMID:20938992 PMID:25629700

NCBI chr15:105,690,283...105,912,347
Ensembl chr15:105,690,295...105,912,345

G

cytidine monophospho-N-acetylneuraminic acid hydroxylase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CMAH mRNA

NCBI chr17:40,985,129...41,070,317
Ensembl chr17:41,011,641...41,070,252

G

cytidine monophosphate N-acetylneuraminic acid synthetase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CMAS mRNA

NCBI chr 4:177,449,801...177,468,117
Ensembl chr 4:177,449,732...177,476,291

G

carboxymethylenebutenolidase homolog

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CMBL mRNA

NCBI chr 2:84,280,128...84,301,878
Ensembl chr 2:84,242,512...84,301,880

G

C-x(9)-C motif containing 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CMC1 mRNA

NCBI chr 8:126,677,560...126,778,403
Ensembl chr 8:126,677,560...126,778,499

G

cytidine/uridine monophosphate kinase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CMPK1 mRNA

NCBI chr 5:133,717,073...133,744,623
Ensembl chr 5:133,717,086...133,744,596

G

cytidine/uridine monophosphate kinase 2

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CMPK2 gene
Folic Acid results in decreased expression of CMPK2 mRNA

PMID:20938992 PMID:25629700

NCBI chr 6:48,802,150...48,813,652
Ensembl chr 6:48,802,321...48,813,652

G

cms1 ribosomal small subunit homolog

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CMSS1 mRNA

NCBI chr11:56,403,620...56,701,751
Ensembl chr11:56,403,499...56,701,755

G

CKLF-like MARVEL transmembrane domain containing 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CMTM3 mRNA

NCBI chr19:629,000...637,152
Ensembl chr19:628,895...636,225

G

CKLF-like MARVEL transmembrane domain containing 5

decreases expression

ISO

Folic Acid results in decreased expression of CMTM5 mRNA

NCBI chr15:32,382,171...32,385,288
Ensembl chr15:32,382,608...32,385,271

G

CKLF-like MARVEL transmembrane domain containing 6

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CMTM6 gene

NCBI chr 8:123,301,131...123,319,230
Ensembl chr 8:123,300,918...123,319,230

G

CKLF-like MARVEL transmembrane domain containing 7

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CMTM7 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CMTM7 mRNA

PMID:20938992 PMID:22206623

NCBI chr 8:123,326,233...123,353,148
Ensembl chr 8:123,325,975...123,353,148

G

CCHC-type zinc finger, nucleic acid binding protein

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CNBP mRNA

NCBI chr 4:121,860,102...121,868,976
Ensembl chr 4:121,860,105...121,869,010

G

carnosine dipeptidase 1

decreases expression

ISO

Folic Acid results in decreased expression of CNDP1 mRNA

NCBI chr18:80,254,499...80,305,845
Ensembl chr18:80,255,784...80,282,643

G

carnosine dipeptidase 2

decreases expression

ISO

Folic Acid results in decreased expression of CNDP2 mRNA

NCBI chr18:80,314,799...80,331,900
Ensembl chr18:80,314,801...80,331,900

G

CTD nuclear envelope phosphatase 1 regulatory subunit 1

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of CNEP1R1 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CNEP1R1 mRNA

PMID:22206623 PMID:25629700

NCBI chr19:35,106,802...35,121,101
Ensembl chr19:35,106,802...35,121,101

G

cyclic nucleotide gated channel subunit alpha 1

decreases expression

ISO

Folic Acid results in decreased expression of CNGA1 mRNA

NCBI chr14:35,920,948...35,959,065
Ensembl chr14:35,926,854...35,959,056

G

cyclic nucleotide gated channel subunit alpha 2

decreases expression

ISO

Folic Acid results in decreased expression of CNGA2 mRNA

NCBI chr X:154,741,742...154,759,814
Ensembl chr X:154,741,764...154,759,814

G

cyclic nucleotide gated channel subunit beta 1

decreases expression

ISO

Folic Acid results in decreased expression of CNGB1 mRNA

NCBI chr19:9,732,646...9,798,864
Ensembl chr19:9,732,646...9,797,224

G

cornichon family member 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CNIH1 mRNA

NCBI chr15:22,517,755...22,529,651
Ensembl chr15:22,497,340...22,529,578

G

cornichon family AMPA receptor auxiliary protein 2

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CNIH2 mRNA]

NCBI chr 1:211,828,791...211,834,474
Ensembl chr 1:211,828,794...211,834,437

G

connector enhancer of kinase suppressor of Ras 1

increases expression

ISO

Folic Acid results in increased expression of CNKSR1 mRNA

NCBI chr 5:151,731,222...151,742,049
Ensembl chr 5:151,731,224...151,742,203

G

connector enhancer of kinase suppressor of Ras 2

decreases expression

ISO

Folic Acid results in decreased expression of CNKSR2 mRNA

NCBI chr X:40,722,843...40,971,730
Ensembl chr X:40,722,996...40,965,604

G

Cnksr family member 3

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of CNKSR3 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CNKSR3 mRNA

PMID:22206623 PMID:25629700

NCBI chr 1:45,904,581...45,996,921
Ensembl chr 1:45,904,581...45,996,921

G

calponin 2

multiple interactions
decreases expression

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CNN2 mRNA]
Folic Acid results in decreased expression of CNN2 mRNA

PMID:22206623 PMID:25629700

NCBI chr 7:10,363,141...10,370,312
Ensembl chr 7:10,363,102...10,370,312

G

calponin 3

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of CNN3 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CNN3 mRNA

PMID:22206623 PMID:25629700

NCBI chr 2:212,203,661...212,234,772
Ensembl chr 2:212,226,640...212,234,815

G

cyclin and CBS domain divalent metal cation transport mediator 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CNNM2 gene

NCBI chr 1:255,585,063...255,709,455
Ensembl chr 1:255,585,095...255,704,849

G

cyclin and CBS domain divalent metal cation transport mediator 3

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CNNM3 gene
Folic Acid results in increased expression of CNNM3 mRNA

PMID:20938992 PMID:25629700

NCBI chr 9:46,251,252...46,266,613
Ensembl chr 9:46,251,265...46,266,613

G

CCR4-NOT transcription complex, subunit 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CNOT2 mRNA

NCBI chr 7:54,016,447...54,117,511
Ensembl chr 7:54,016,447...54,107,960

G

CCR4-NOT transcription complex, subunit 6

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CNOT6 mRNA

NCBI chr10:34,479,892...34,532,166
Ensembl chr10:34,481,938...34,524,416

G

CCR4-NOT transcription complex, subunit 7

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CNOT7 gene

NCBI chr16:58,478,882...58,498,046
Ensembl chr16:58,478,900...58,498,046

G

CCR4-NOT transcription complex, subunit 8

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of and results in decreased expression of CNOT8; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CNOT8 gene

NCBI chr10:42,782,042...42,795,207
Ensembl chr10:42,782,283...42,795,207

G

2',3'-cyclic nucleotide 3' phosphodiesterase

multiple interactions
decreases expression

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CNP mRNA]
Folic Acid results in decreased expression of CNP mRNA

PMID:22206623 PMID:25629700

NCBI chr10:86,011,504...86,018,063
Ensembl chr10:86,011,495...86,018,063

G

canopy FGF signaling regulator 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CNPY2 mRNA

NCBI chr 7:1,332,293...1,338,081
Ensembl chr 7:1,334,335...1,340,333

G

canopy FGF signaling regulator 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CNPY3 mRNA

NCBI chr 9:21,731,088...21,745,448
Ensembl chr 9:21,730,791...21,745,505

G

canopy FGF signaling regulator 4

decreases expression

ISO

Folic Acid results in decreased expression of CNPY4 mRNA

NCBI chr12:22,178,254...22,184,432
Ensembl chr12:22,178,160...22,184,425

G

cannabinoid receptor 1

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CNR1 gene
Folic Acid results in increased expression of CNR1 mRNA

PMID:20938992 PMID:25006883

NCBI chr 5:53,204,867...53,230,396
Ensembl chr 5:53,204,260...53,239,252

G

cannabinoid receptor 2

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of CNR2 mRNA; Folic Acid results in decreased expression of CNR2 protein
6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride inhibits the reaction [celastrol inhibits the reaction [Folic Acid results in decreased expression of CNR2 protein]]; celastrol inhibits the reaction [Folic Acid results in decreased expression of CNR2 protein]

PMID:25629700 PMID:29789558

NCBI chr 5:153,408,968...153,435,092
Ensembl chr 5:153,409,147...153,435,961

G

cannabinoid receptor interacting protein 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CNRIP1 mRNA

NCBI chr14:95,664,435...95,707,062
Ensembl chr14:95,664,774...95,694,371

G

consortin, connexin sorting protein

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of CNST mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CNST mRNA

PMID:22206623 PMID:25629700

NCBI chr13:93,828,694...93,905,497
Ensembl chr13:93,828,687...93,905,490

G

ciliary neurotrophic factor

multiple interactions

ISO

Folic Acid affects the reaction [Cisplatin affects the expression of CNTF mRNA]

NCBI chr 1:219,312,512...219,314,535
Ensembl chr 1:219,312,512...219,314,488

G

centlein

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CNTLN gene
Folic Acid results in decreased expression of CNTLN mRNA

PMID:20938992 PMID:25629700

NCBI chr 5:104,340,801...104,622,491
Ensembl chr 5:104,342,173...104,630,976

G

contactin 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CNTN1 mRNA

NCBI chr 7:125,142,638...125,440,397
Ensembl chr 7:125,142,696...125,440,391

G

contactin 2

decreases expression

ISO

Folic Acid results in decreased expression of CNTN2 mRNA

NCBI chr13:46,497,269...46,528,112
Ensembl chr13:46,499,396...46,528,027

G

contactin 3

decreases expression

ISO

Folic Acid results in decreased expression of CNTN3 mRNA

NCBI chr 4:136,397,575...136,770,765
Ensembl chr 4:136,398,572...136,770,717

G

contactin 6

decreases expression

ISO

Folic Acid results in decreased expression of CNTN6 mRNA

PMID:21867686 PMID:25629700

NCBI chr 4:138,911,090...139,307,339
Ensembl chr 4:138,911,380...139,311,816

G

contactin associated protein 2

decreases expression

ISO

Folic Acid results in decreased expression of CNTNAP2 mRNA

NCBI chr 4:75,109,358...77,366,258
Ensembl chr 4:75,109,858...77,366,258

G

cytochrome C oxidase assembly factor 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COA3 mRNA

NCBI chr10:86,720,454...86,721,435
Ensembl chr10:86,720,456...86,721,440

G

cytochrome c oxidase assembly factor 4 homolog

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COA4 mRNA
Folic Acid results in decreased expression of COA4 mRNA

PMID:22206623 PMID:25629700

NCBI chr 1:164,294,312...164,297,571
Ensembl chr 1:164,294,319...164,297,578

G

cytochrome C oxidase assembly factor 5

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COA5 mRNA

NCBI chr 9:47,147,267...47,160,724
Ensembl chr 9:47,147,267...47,160,672

G

cytochrome c oxidase assembly factor 6

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COA6 mRNA

NCBI chr19:71,293,066...71,295,668
Ensembl chr19:71,278,765...71,296,015

G

cytochrome c oxidase assembly factor 8

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of COA8 mRNA

NCBI chr 6:136,593,399...136,618,237
Ensembl chr 6:136,592,787...136,619,602

G

cordon-bleu WH2 repeat protein

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COBL mRNA

NCBI chr14:91,041,721...91,274,272
Ensembl chr14:91,041,721...91,274,257

G

cordon-bleu WH2 repeat protein-like 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COBLL1 mRNA

NCBI chr 3:70,161,369...70,324,844
Ensembl chr 3:70,161,372...70,323,460

G

cochlin

decreases expression

ISO

Folic Acid results in decreased expression of COCH mRNA

NCBI chr 6:74,766,485...74,780,504
Ensembl chr 6:74,766,419...74,780,502

G

component of oligomeric golgi complex 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of COG1 gene

NCBI chr10:99,192,604...99,207,640
Ensembl chr10:99,194,568...99,208,437

G

component of oligomeric golgi complex 3

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COG3 mRNA
Folic Acid results in decreased expression of COG3 mRNA

PMID:22206623 PMID:25629700

NCBI chr15:57,389,994...57,480,454
Ensembl chr15:57,390,238...57,480,097

G

component of oligomeric golgi complex 4

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COG4 mRNA

NCBI chr19:55,729,854...55,763,902
Ensembl chr19:55,728,796...55,764,169

G

component of oligomeric golgi complex 6

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of COG6 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COG6 mRNA

PMID:22206623 PMID:25629700

NCBI chr 2:139,212,459...139,249,505
Ensembl chr 2:139,211,678...139,249,737

G

component of oligomeric golgi complex 7

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COG7 mRNA

NCBI chr 1:185,921,053...185,980,711
Ensembl chr 1:185,889,348...185,983,421

G

coilin

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COIL mRNA

NCBI chr10:74,286,279...74,307,597
Ensembl chr10:74,286,840...74,307,595

G

collagen type XIV alpha 1 chain

decreases expression

ISO

Folic Acid results in decreased expression of COL14A1 mRNA

NCBI chr 7:88,611,827...88,826,939
Ensembl chr 7:88,611,828...88,826,938

G

collagen type XVI alpha 1 chain

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of COL16A1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of COL16A1 mRNA

PMID:20548288 PMID:20938992 PMID:22206623

NCBI chr 5:147,672,559...147,727,007
Ensembl chr 5:147,672,601...147,727,011

G

collagen type XVIII alpha 1 chain

multiple interactions

ISO

Folic Acid inhibits the reaction [AGT protein results in increased expression of COL18A1 protein]

NCBI chr20:11,473,645...11,582,111
Ensembl chr20:11,473,645...11,582,112

G

collagen type I alpha 1 chain

multiple interactions
increases expression

ISO
EXP

[Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of COL1A1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of COL1A1 mRNA
[Methionine co-treated with Betaine co-treated with Choline co-treated with Folic Acid] inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]; [Methionine co-treated with Betaine co-treated with Choline co-treated with Folic Acid] inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 protein]
Folic Acid results in increased expression of COL1A1 mRNA; Folic Acid results in increased expression of COL1A1 protein

PMID:20548288 PMID:20938992 PMID:23439872 PMID:34619300 PMID:39736447

NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460

G

collagen type I alpha 2 chain

multiple interactions
increases expression

EXP
ISO

[Carbon Tetrachloride co-treated with Folic Acid] results in increased expression of COL1A2 mRNA
Folic Acid results in increased expression of COL1A2 mRNA; Folic Acid results in increased expression of COL1A2 protein
[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of COL1A2 mRNA; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of COL1A2 mRNA]

PMID:18156304 PMID:20548288 PMID:20938992 PMID:22206623 PMID:24275386 More...

NCBI chr 4:33,518,557...33,553,484
Ensembl chr 4:33,518,420...33,553,995

G

collagen type XX alpha 1 chain

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of COL20A1 mRNA

NCBI chr 3:188,477,663...188,512,326
Ensembl chr 3:188,465,648...188,511,078

G

collagen type XXII alpha 1 chain

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of COL22A1 mRNA

NCBI chr 7:105,619,776...105,857,246
Ensembl chr 7:105,619,757...105,856,960

G

collagen type XXV alpha 1 chain

decreases expression

ISO

Folic Acid results in decreased expression of COL25A1 mRNA

NCBI chr 2:221,429,378...221,828,536
Ensembl chr 2:221,429,958...221,828,535

G

collagen type XXVII alpha 1 chain

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of COL27A1 gene

NCBI chr 5:81,662,822...81,781,502
Ensembl chr 5:81,661,685...81,781,502

G

collagen type II alpha 1 chain

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of COL2A1 gene

NCBI chr 7:130,977,561...131,006,627
Ensembl chr 7:130,977,561...131,006,627

G

collagen type III alpha 1 chain

multiple interactions
increases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of COL3A1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of COL3A1 mRNA
Folic Acid results in increased expression of COL3A1 mRNA

PMID:20548288 PMID:20938992 PMID:22206623 PMID:34619300

NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:54,866,632...54,903,232

G

collagen type IV alpha 1 chain

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of COL4A1 mRNA; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of COL4A1 mRNA]; Metformin inhibits the reaction [Folic Acid results in increased expression of COL4A1 mRNA]
Folic Acid inhibits the reaction [TGFB1 protein results in increased expression of COL4A1 mRNA]

PMID:20938992 PMID:22206623 PMID:29380373

NCBI chr16:84,885,597...84,996,482
Ensembl chr16:84,885,597...84,996,482

G

collagen type IV alpha 5 chain

decreases expression

ISO

Folic Acid results in decreased expression of COL4A5 mRNA

NCBI chr X:109,907,251...110,111,214
Ensembl chr X:109,907,346...110,111,214

G

collagen type IV alpha 6 chain

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of COL4A6 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of COL4A6 mRNA
Folic Acid results in decreased expression of COL4A6 mRNA

PMID:20548288 PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr X:109,554,945...109,905,987
Ensembl chr X:109,552,651...109,905,944

G

collagen type V alpha 1 chain

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of COL5A1 mRNA

NCBI chr 3:31,606,475...31,755,097
Ensembl chr 3:31,606,486...31,753,020

G

collagen type V alpha 2 chain

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of COL5A2 mRNA

PMID:20548288 PMID:20938992

NCBI chr 9:54,940,768...55,090,151
Ensembl chr 9:54,940,764...55,090,150

G

collagen type VI alpha 1 chain

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of COL6A1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of COL6A1 mRNA

PMID:20548288 PMID:20938992 PMID:22206623

NCBI chr20:11,905,690...11,924,111
Ensembl chr20:11,905,457...11,924,107

G

collagen type VI alpha 2 chain

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of COL6A2 mRNA]

NCBI chr20:12,021,182...12,048,932
Ensembl chr20:12,021,265...12,057,042

G

collagen type VI alpha 3 chain

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of COL6A3 mRNA

NCBI chr 9:98,809,171...98,887,060
Ensembl chr 9:98,809,171...98,886,990

G

collagen type VI alpha 5 chain

increases expression

ISO

Folic Acid results in increased expression of COL6A5 mRNA

NCBI chr 8:115,362,532...115,462,844
Ensembl chr 8:115,361,906...115,462,859

G

collagen type VII alpha 1 chain

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of COL7A1 mRNA

NCBI chr 8:118,483,364...118,515,736
Ensembl chr 8:118,483,364...118,517,439

G

collagen type VIII alpha 1 chain

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of COL8A1 mRNA

NCBI chr11:56,245,998...56,378,586
Ensembl chr11:56,369,868...56,376,229

G

collagen type VIII alpha 2 chain

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of COL8A2 gene

NCBI chr 5:143,870,754...143,897,372
Ensembl chr 5:143,870,742...143,897,884

G

collagen type IX alpha 1 chain

increases expression

ISO

Folic Acid results in increased expression of COL9A1 mRNA

NCBI chr 9:34,081,364...34,164,552
Ensembl chr 9:34,003,905...34,164,543

G

collectin sub-family member 12

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of COLEC12 gene

NCBI chr18:1,005,787...1,193,455
Ensembl chr18:1,005,741...1,195,297

G

collagen beta(1-O)galactosyltransferase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COLGALT1 mRNA

NCBI chr16:18,353,779...18,366,087
Ensembl chr16:18,353,570...18,366,086

G

copper metabolism domain containing 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COMMD1 mRNA

NCBI chr14:101,081,667...101,185,738
Ensembl chr14:101,081,667...101,185,639

G

COMM domain containing 10

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COMMD10 mRNA

NCBI chr18:41,927,802...42,061,384
Ensembl chr18:41,921,694...42,086,729

G

COMM domain containing 2

decreases expression

ISO

Folic Acid results in decreased expression of COMMD2 mRNA

NCBI chr 2:143,998,672...144,002,918
Ensembl chr 2:143,998,672...144,002,918

G

COMM domain containing 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COMMD3 mRNA

NCBI chr17:86,235,863...86,239,610
Ensembl chr17:86,235,863...86,239,610

G

COMM domain containing 4

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COMMD4 mRNA

NCBI chr 8:66,462,188...66,465,700
Ensembl chr 8:66,462,188...66,465,756

G

COMM domain containing 5

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COMMD5 mRNA

NCBI chr 7:110,502,492...110,503,916
Ensembl chr 7:110,479,403...110,505,897

G

COMM domain containing 6

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COMMD6 mRNA

NCBI chr15:84,882,069...84,889,124
Ensembl chr15:84,882,548...84,889,194

G

COMM domain containing 7

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COMMD7 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of COMMD7 gene

PMID:20938992 PMID:22206623

NCBI chr 3:162,559,762...162,574,543
Ensembl chr 3:162,554,374...162,574,692

G

COMM domain containing 8

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of COMMD8 gene

NCBI chr14:36,403,000...36,413,577
Ensembl chr14:36,403,022...36,413,574

G

COMM domain containing 9

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COMMD9 mRNA
Folic Acid results in decreased expression of COMMD9 mRNA

PMID:22206623 PMID:25629700

NCBI chr 3:108,630,903...108,645,427
Ensembl chr 3:108,630,980...108,666,091

G

catechol-O-methyltransferase domain containing 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COMTD1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of COMTD1; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of COMTD1 gene

PMID:20938992 PMID:22206623

NCBI chr15:2,509,121...2,512,232
Ensembl chr15:2,509,032...2,512,232

G

COPI coat complex subunit alpha

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of COPA mRNA]

NCBI chr13:87,078,853...87,119,256
Ensembl chr13:87,078,383...87,119,256

G

COPI coat complex subunit beta 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of COPB1 mRNA

NCBI chr 1:177,838,751...177,876,688
Ensembl chr 1:177,838,752...177,872,840

G

COPI coat complex subunit beta 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COPB2 mRNA

NCBI chr 8:108,040,687...108,062,810
Ensembl chr 8:108,040,693...108,064,550

G

COPI coat complex subunit epsilon

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COPE mRNA

NCBI chr16:19,148,832...19,159,052
Ensembl chr16:19,148,832...19,159,212

G

COPI coat complex subunit gamma 1

decreases expression

ISO

Folic Acid results in decreased expression of COPG1 mRNA

NCBI chr 4:121,923,644...121,949,819
Ensembl chr 4:121,923,873...121,949,812

G

coordinator of PRMT5 and differentiation stimulator

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COPRS mRNA

NCBI chr16:82,423,426...82,428,821
Ensembl chr16:82,407,580...82,431,737

G

COP9 signalosome subunit 2

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of COPS2 mRNA]

NCBI chr 3:133,537,729...133,563,493
Ensembl chr 3:133,537,732...133,563,369

G

COP9 signalosome subunit 3

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of COPS3 mRNA]

NCBI chr10:45,117,664...45,151,868
Ensembl chr10:45,117,657...45,152,074

G

COP9 signalosome subunit 4

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COPS4 mRNA

NCBI chr14:9,382,897...9,413,216
Ensembl chr14:9,382,900...9,413,107

G

COP9 signalosome subunit 5

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of COPS5 mRNA]

NCBI chr 5:13,975,198...13,993,391
Ensembl chr 5:13,975,052...13,993,387

G

COP9 signalosome subunit 7B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COPS7B mRNA

NCBI chr 9:94,686,314...94,711,903
Ensembl chr 9:94,686,314...94,711,903

G

COP9 signalosome subunit 8

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of COPS8 mRNA
Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of COPS8 mRNA]

PMID:22206623 PMID:25629700

NCBI chr 9:98,655,031...98,664,861
Ensembl chr 9:98,654,870...98,665,381

G

COPI coat complex subunit zeta 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COPZ1 mRNA

NCBI chr 7:136,287,696...136,314,131
Ensembl chr 7:136,288,032...136,314,135

G

coenzyme Q10B

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COQ10B mRNA
Folic Acid results in decreased expression of COQ10B mRNA

PMID:22206623 PMID:25629700

NCBI chr 9:64,048,168...64,068,082
Ensembl chr 9:64,048,103...64,068,322

G

coenzyme Q2, polyprenyltransferase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COQ2 mRNA

NCBI chr14:9,245,777...9,265,784
Ensembl chr14:9,245,803...9,265,783

G

coenzyme Q3 methyltransferase

decreases expression

ISO

Folic Acid results in decreased expression of COQ3 mRNA

NCBI chr 5:40,226,313...40,257,383
Ensembl chr 5:40,226,368...40,257,617

G

coenzyme Q4

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COQ4 mRNA

NCBI chr 3:33,457,834...33,468,387
Ensembl chr 3:33,457,596...33,468,379

G

coenzyme Q5, methyltransferase

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of COQ5 mRNA

NCBI chr12:46,977,632...46,994,575
Ensembl chr12:46,977,632...46,994,712

G

coenzyme Q6 monooxygenase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of COQ6 mRNA

NCBI chr 6:109,738,934...109,750,315
Ensembl chr 6:109,738,951...109,750,310

G

coenzyme Q7, hydroxylase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COQ7 mRNA

NCBI chr 1:182,270,570...182,285,959
Ensembl chr 1:182,269,399...182,285,508

G

coenzyme Q8B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of COQ8B mRNA

NCBI chr 1:91,653,241...91,676,822
Ensembl chr 1:91,654,225...91,676,819

G

coenzyme Q9

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COQ9 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of COQ9 gene
Folic Acid results in decreased expression of COQ9 mRNA

PMID:20938992 PMID:21867686 PMID:22206623 PMID:25629700

NCBI chr19:10,172,943...10,185,960
Ensembl chr19:10,172,949...10,185,937

G

coronin 1A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CORO1A mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CORO1A mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CORO1A gene

PMID:20938992 PMID:22206623

NCBI chr 1:190,726,129...190,731,133
Ensembl chr 1:190,726,130...190,731,102

G

coronin 1B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CORO1B mRNA

NCBI chr 1:210,872,437...210,877,876
Ensembl chr 1:210,871,841...210,877,876

G

coronin 2A

decreases expression

ISO

Folic Acid results in decreased expression of CORO2A mRNA

NCBI chr 5:65,623,820...65,677,483
Ensembl chr 5:65,623,823...65,654,602

G

coronin 6

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CORO6 gene

NCBI chr10:62,808,172...62,817,788
Ensembl chr10:62,809,689...62,817,787

G

coactosin-like F-actin binding protein 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of COTL1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of COTL1 gene

NCBI chr19:64,780,309...64,814,629
Ensembl chr19:64,780,322...64,814,840

G

cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of COX10 gene

NCBI chr10:49,130,209...49,242,009
Ensembl chr10:49,130,209...49,242,009

G

cytochrome c oxidase copper chaperone COX11

decreases expression
affects expression
multiple interactions

ISO

Folic Acid results in decreased expression of COX11 mRNA
Folic Acid affects the expression of COX11 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COX11 mRNA

PMID:21867686 PMID:22206623 PMID:25629700

NCBI chr10:75,955,825...75,962,398
Ensembl chr10:75,955,783...75,963,489

G

cytochrome c oxidase assembly factor COX14

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COX14 mRNA

NCBI chr 7:132,731,069...132,733,159
Ensembl chr 7:132,731,069...132,733,159

G

cytochrome c oxidase assembly homolog COX15

decreases expression

ISO

Folic Acid results in decreased expression of COX15 mRNA

NCBI chr 1:252,554,811...252,571,471
Ensembl chr 1:252,554,811...252,571,471

G

cytochrome c oxidase assembly factor COX16

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COX16 mRNA

NCBI chr 6:106,745,424...106,912,523
Ensembl chr 6:106,899,494...106,912,484

G

cytochrome c oxidase copper chaperone COX17

decreases expression

ISO

Folic Acid results in decreased expression of COX17 mRNA

NCBI chr11:75,906,245...75,912,036
Ensembl chr11:75,906,248...75,912,019

G

cytochrome c oxidase assembly factor COX19

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COX19 mRNA

NCBI chr12:20,417,389...20,426,868
Ensembl chr12:20,417,341...20,426,868

G

cytochrome c oxidase assembly factor COX20

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COX20 mRNA

NCBI chr13:92,592,260...92,604,129
Ensembl chr14:6,872,315...6,872,638

G

cytochrome c oxidase subunit 4i1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COX4I1 mRNA

NCBI chr19:65,630,383...65,636,623
Ensembl chr19:65,630,432...65,636,624

G

cytochrome c oxidase subunit 4i2

decreases expression

ISO

Folic Acid results in decreased expression of COX4I2 mRNA

NCBI chr 3:161,686,193...161,699,605
Ensembl chr 3:161,689,017...161,699,602

G

cytochrome c oxidase subunit 5A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COX5A mRNA

NCBI chr 8:66,818,284...66,829,691
Ensembl chr 8:66,818,196...66,830,279

G

cytochrome c oxidase subunit 5B

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COX5B mRNA
Folic Acid results in decreased expression of COX5B mRNA

PMID:22206623 PMID:25629700

NCBI chr 9:46,417,735...46,419,664
Ensembl chr 9:46,417,838...46,420,403

G

cytochrome c oxidase subunit 6A1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COX6A1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of COX6A1 gene

PMID:20938992 PMID:22206623

NCBI chr12:46,922,709...46,925,762
Ensembl chr12:46,912,648...46,925,768

G

cytochrome c oxidase subunit 6A2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of COX6A2 mRNA

NCBI chr 1:192,218,970...192,221,188
Ensembl chr 1:192,218,970...192,219,716

G

cytochrome c oxidase subunit 6B1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COX6B1 mRNA

NCBI chr 1:95,002,513...95,011,516
Ensembl chr 1:95,001,707...95,011,431
Ensembl chr 5:95,001,707...95,011,431

G

cytochrome c oxidase subunit 6C

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COX6C mRNA

NCBI chr 7:69,014,410...69,027,145
Ensembl chr 7:69,014,417...69,027,166

G

cytochrome c oxidase subunit 7A2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COX7A2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of COX7A2 gene

PMID:20938992 PMID:22206623

NCBI chr 8:89,597,051...89,611,032
Ensembl chr14:55,514,261...55,514,512
Ensembl chr 8:55,514,261...55,514,512

G

cytochrome c oxidase subunit 7B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COX7B mRNA

NCBI chr X:75,149,036...75,155,285
Ensembl chr X:75,148,996...75,155,284

G

cytochrome c oxidase subunit 7C

decreases expression

ISO

Folic Acid results in decreased expression of COX7C mRNA

NCBI chr 2:18,577,145...18,579,170
Ensembl chr 2:18,577,149...18,579,170

G

cytochrome c oxidase subunit 8A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COX8A mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of COX8A gene

PMID:20938992 PMID:22206623

NCBI chr 1:213,831,302...213,833,623
Ensembl chr 1:213,831,298...213,833,623

G

centrosome assembly and centriole elongation protein

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CPAP mRNA

NCBI chr15:34,742,838...34,806,020
Ensembl chr15:34,742,838...34,802,421

G

carboxypeptidase B2

increases expression

ISO

Folic Acid results in increased expression of CPB2 mRNA

NCBI chr15:56,967,128...57,015,964
Ensembl chr15:56,966,839...57,015,962

G

carboxypeptidase D

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CPD gene
Folic Acid results in decreased expression of CPD mRNA

PMID:20938992 PMID:25629700

NCBI chr10:62,121,681...62,185,638
Ensembl chr10:62,121,679...62,185,638

G

carboxypeptidase E

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CPE mRNA]

NCBI chr16:29,796,707...29,908,647
Ensembl chr16:29,796,689...29,909,524

G

cytoplasmic polyadenylation element binding protein 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CPEB1 gene
Folic Acid results in decreased expression of CPEB1 mRNA

PMID:20938992 PMID:25629700

NCBI chr 1:144,709,278...144,817,388
Ensembl chr 1:144,709,691...144,815,880

G

cytoplasmic polyadenylation element binding protein 2

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CPEB2 gene
Folic Acid results in decreased expression of CPEB2 mRNA

PMID:20938992 PMID:21867686

NCBI chr14:71,999,958...72,056,012
Ensembl chr14:72,002,072...72,052,263

G

cytoplasmic polyadenylation element binding protein 3

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of CPEB3 mRNA
Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CPEB3 mRNA]

PMID:21867686 PMID:22206623

NCBI chr 1:244,161,690...244,343,765
Ensembl chr 1:244,161,690...244,343,561

G

complexin 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CPLX2 gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CPLX2 mRNA]

PMID:20938992 PMID:22206623

NCBI chr17:10,224,673...10,297,974
Ensembl chr17:10,228,449...10,297,467

G

complexin 3

increases expression

ISO

Folic Acid results in increased expression of CPLX3 mRNA

NCBI chr 8:66,899,438...66,906,200
Ensembl chr 8:66,899,438...66,906,200

G

carboxypeptidase N subunit 2

decreases expression

ISO

Folic Acid results in decreased expression of CPN2 mRNA

NCBI chr11:83,990,943...84,000,821
Ensembl chr11:83,990,940...84,001,059

G

copine 1

increases expression

ISO

Folic Acid results in increased expression of CPNE1 mRNA

NCBI chr 3:165,047,615...165,089,994

G

copine 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CPNE3 mRNA

NCBI chr 5:37,811,566...37,860,840
Ensembl chr 5:37,811,566...37,861,062

G

copine 4

decreases expression

ISO

Folic Acid results in decreased expression of CPNE4 mRNA

NCBI chr 8:114,056,152...114,531,855
Ensembl chr 8:113,993,703...114,531,855

G

copine 6

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CPNE6 mRNA

NCBI chr15:32,968,047...32,975,008
Ensembl chr15:32,968,046...32,975,007

G

copine 7

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CPNE7 mRNA
Folic Acid results in increased expression of CPNE7 mRNA

PMID:20938992 PMID:25629700

NCBI chr19:68,072,165...68,091,197
Ensembl chr19:68,074,545...68,091,197

G

copine 8

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CPNE8 mRNA
Folic Acid results in decreased expression of CPNE8 mRNA

PMID:20938992 PMID:25629700

NCBI chr 7:123,494,864...123,669,060
Ensembl chr 7:123,494,865...123,669,060

G

coproporphyrinogen oxidase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CPOX mRNA

NCBI chr11:55,405,778...55,415,761
Ensembl chr11:55,405,784...55,415,761

G

calcineurin-like phosphoesterase domain containing 1

increases expression

ISO

Folic Acid results in increased expression of CPPED1 mRNA

NCBI chr10:4,135,601...4,328,039
Ensembl chr10:4,208,463...4,231,065

G

carboxypeptidase Q

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CPQ mRNA
Folic Acid results in decreased expression of CPQ mRNA

PMID:21867686 PMID:22206623

NCBI chr 7:66,148,973...66,719,189
Ensembl chr 7:66,149,377...66,716,137

G

cleavage and polyadenylation specific factor 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of and results in decreased expression of CPSF1; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CPSF1 gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CPSF1 mRNA]
Folic Acid results in decreased expression of CPSF1 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr 7:110,200,078...110,210,644
Ensembl chr 7:110,199,066...110,210,644

G

cleavage and polyadenylation specific factor 4

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CPSF4 mRNA

NCBI chr12:14,543,536...14,559,350
Ensembl chr12:14,543,338...14,559,350

G

cleavage and polyadenylation specific factor 6

decreases expression

ISO

Folic Acid results in decreased expression of CPSF6 mRNA

NCBI chr 7:54,798,452...54,887,711
Ensembl chr 7:54,842,490...54,873,998

G

carnitine palmitoyltransferase 1A

multiple interactions
increases expression

ISO
EXP

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CPT1A mRNA
Folic Acid deficiency results in increased expression of CPT1A mRNA

PMID:19566968 PMID:22206623

NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:209,993,875...210,056,326

G

carnitine palmitoyltransferase 1B

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CPT1B mRNA
Folic Acid results in increased expression of CPT1B mRNA

PMID:20938992 PMID:25629700

NCBI chr 7:122,370,974...122,380,473
Ensembl chr 7:122,370,444...122,380,036

G

carnitine palmitoyltransferase 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CPT2 mRNA

NCBI chr 5:127,893,450...127,911,347
Ensembl chr 5:127,893,207...127,910,818

G

carboxypeptidase X (M14 family), member 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CPXM1 mRNA

NCBI chr 3:138,041,645...138,048,443
Ensembl chr 3:138,041,645...138,048,857

G

carboxypeptidase Z

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CPZ mRNA

NCBI chr14:79,448,242...79,471,557
Ensembl chr14:79,448,139...79,471,556

G

complement C3b/C4b receptor 1 like

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CR1L mRNA

NCBI chr13:109,138,132...109,189,068
Ensembl chr13:109,103,235...109,188,869

G

cellular retinoic acid binding protein 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CRABP1 gene

NCBI chr 8:64,047,431...64,055,469
Ensembl chr 8:64,047,060...64,055,470

G

CRACD like

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CRACDL mRNA

NCBI chr 9:47,323,785...47,446,612
Ensembl chr 9:47,329,902...47,445,310

G

calcium release activated channel regulator 2B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CRACR2B mRNA

NCBI chr 1:205,987,957...205,993,515
Ensembl chr 1:205,990,507...205,993,516

G

CASP2 and RIPK1 domain containing adaptor with death domain

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CRADD gene

NCBI chr 7:31,827,131...31,839,796
Ensembl chr 7:31,685,622...31,874,512

G

cramped chromatin regulator homolog 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CRAMP1 gene
Folic Acid results in decreased expression of CRAMP1 mRNA

PMID:20938992 PMID:25629700

NCBI chr10:14,488,292...14,536,844
Ensembl chr10:14,467,661...14,535,664

G

carnitine O-acetyltransferase

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CRAT gene

NCBI chr 3:34,073,504...34,087,099
Ensembl chr 3:34,073,506...34,087,099

G

cereblon

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CRBN gene

NCBI chr 4:141,255,400...141,276,722
Ensembl chr 4:141,257,243...141,276,038

G

cysteine-rich C-terminal 1

decreases expression

ISO

Folic Acid results in decreased expression of CRCT1 mRNA

NCBI chr 2:181,329,392...181,330,877
Ensembl chr 2:181,329,392...181,330,877

G

cAMP responsive element binding protein 1

multiple interactions
decreases expression
affects methylation
increases activity

EXP
ISO

CREB1 protein promotes the reaction [Folic Acid results in increased expression of PTHLH mRNA]; Losartan inhibits the reaction [Folic Acid results in increased activity of CREB1 protein]
Folic Acid results in decreased expression of CREB1 mRNA
Folic Acid affects the methylation of CREB1 gene
[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CREB1 mRNA

PMID:15728788 PMID:20938992 PMID:21867686 PMID:24629913 PMID:25629700

NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339

G

cAMP responsive element binding protein 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CREB3 mRNA

NCBI chr 5:62,613,652...62,619,019
Ensembl chr 5:62,613,638...62,619,500

G

cAMP responsive element binding protein 3-like 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CREB3L1 mRNA

NCBI chr 3:98,408,240...98,449,104
Ensembl chr 3:98,408,058...98,449,104

G

cAMP responsive element binding protein 3-like 2

decreases expression

ISO

Folic Acid results in decreased expression of CREB3L2 mRNA

NCBI chr 4:66,874,623...66,990,962
Ensembl chr 4:66,387,126...66,990,832

G

cAMP responsive element binding protein 3-like 4

decreases expression

ISO

Folic Acid results in decreased expression of CREB3L4 mRNA

NCBI chr 2:177,987,981...177,994,568
Ensembl chr 2:177,987,981...177,993,485

G

cAMP responsive element binding protein 5

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CREB5 mRNA

NCBI chr 4:83,723,587...84,124,786
Ensembl chr 4:83,723,194...84,120,793

G

CREB binding protein

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CREBBP gene

NCBI chr10:11,842,307...11,968,266
Ensembl chr10:11,822,620...11,968,266

G

CREB/ATF bZIP transcription factor

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CREBZF mRNA
Folic Acid results in decreased expression of CREBZF mRNA

PMID:22206623 PMID:25629700

NCBI chr 1:153,829,544...153,836,073
Ensembl chr 1:153,829,448...153,845,122

G

cellular repressor of E1A-stimulated genes 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CREG1 mRNA

NCBI chr13:80,552,779...80,565,272
Ensembl chr13:80,549,933...80,565,272

G

cellular repressor of E1A-stimulated genes 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CREG2 mRNA

NCBI chr 9:49,367,693...49,441,133
Ensembl chr 9:49,399,114...49,440,985

G

cysteine-rich with EGF-like domains 1

decreases expression

ISO

Folic Acid results in decreased expression of CRELD1 mRNA

NCBI chr 4:148,187,510...148,197,120
Ensembl chr 4:148,187,265...148,197,116

G

cysteine-rich with EGF-like domains 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CRELD2 mRNA

NCBI chr 7:121,788,754...121,796,230
Ensembl chr 7:121,788,745...121,796,228

G

cAMP responsive element modulator

decreases expression

ISO

Folic Acid results in decreased expression of CREM mRNA

NCBI chr17:58,932,011...59,001,160
Ensembl chr17:58,934,147...59,001,160

G

cysteine rich transmembrane BMP regulator 1

decreases expression

ISO

Folic Acid results in decreased expression of CRIM1 mRNA

NCBI chr 6:22,447,983...22,622,459
Ensembl chr 6:22,449,948...22,622,416

G

cysteine rich protein 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CRIP1 mRNA

NCBI chr 6:138,047,801...138,055,672
Ensembl chr 6:138,047,801...138,055,672

G

CXXC repeat containing interactor of PDZ3 domain

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CRIPT mRNA
Folic Acid results in decreased expression of CRIPT mRNA

PMID:22206623 PMID:25629700

NCBI chr 6:13,334,978...13,342,934
Ensembl chr 6:13,334,954...13,345,044

G

cripto, EGF-CFC family member

increases expression

ISO

Folic Acid results in increased expression of CRIPTO mRNA

NCBI chr 8:119,803,182...119,808,714
Ensembl chr 8:119,803,220...119,808,948

G

CRK proto-oncogene, adaptor protein

decreases expression

ISO

Folic Acid results in decreased expression of CRK mRNA

NCBI chr10:61,028,736...61,054,971
Ensembl chr10:61,028,757...61,082,988

G

CRK like proto-oncogene, adaptor protein

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CRKL mRNA

NCBI chr11:97,033,033...97,067,457
Ensembl chr11:97,024,782...97,067,457

G

cytokine receptor-like factor 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CRLF1 gene

NCBI chr16:18,958,695...18,970,026
Ensembl chr16:18,957,956...18,969,970

G

cytokine receptor-like factor 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CRLF3 mRNA

NCBI chr10:65,521,296...65,559,162
Ensembl chr10:65,521,492...65,558,804

G

cardiolipin synthase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CRLS1 mRNA

NCBI chr 3:140,572,680...140,591,543
Ensembl chr 3:140,572,716...140,591,599

G

collapsin response mediator protein 1

multiple interactions
decreases expression

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CRMP1 mRNA]
Folic Acid results in decreased expression of CRMP1 mRNA

PMID:22206623 PMID:25629700

NCBI chr14:77,734,675...77,780,916
Ensembl chr14:77,734,675...77,780,916

G

ciliary rootlet coiled-coil, rootletin

decreases expression

ISO

Folic Acid results in decreased expression of CROCC mRNA

NCBI chr 5:158,603,979...158,646,728
Ensembl chr 5:158,603,556...158,640,238

G

C-reactive protein

multiple interactions
decreases expression

ISO

[Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with Oleic Acid co-treated with Folic Acid co-treated with Vitamin B 6 co-treated with Vitamin E] results in decreased expression of CRP protein; [Folic Acid co-treated with Riboflavin co-treated with Vitamin B 6 co-treated with Vitamin B 12] results in decreased expression of CRP protein; [Vitamin E co-treated with Ascorbic Acid co-treated with Folic Acid co-treated with Riboflavin co-treated with Vitamin B 6 co-treated with Vitamin B 12] results in decreased expression of CRP protein
Folic Acid results in decreased expression of CRP protein

PMID:16491109 PMID:16517955 PMID:17237316

NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514

G

cartilage acidic protein 1

multiple interactions
decreases expression

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CRTAC1 mRNA]
Folic Acid results in decreased expression of CRTAC1 mRNA

PMID:22206623 PMID:25629700

NCBI chr 1:251,040,963...251,182,920
Ensembl chr 1:251,028,143...251,182,689

G

cartilage associated protein

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CRTAP mRNA

NCBI chr 8:122,926,117...122,945,843
Ensembl chr 8:122,926,117...122,945,843

G

CREB regulated transcription coactivator 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CRTC2 mRNA

NCBI chr 2:178,007,233...178,017,397
Ensembl chr 2:178,007,240...178,017,389

G

CREB regulated transcription coactivator 3

decreases expression

ISO

Folic Acid results in decreased expression of CRTC3 mRNA

NCBI chr 1:143,962,038...144,064,324
Ensembl chr 1:143,962,038...144,064,288

G

cryptochrome circadian regulator 1

decreases expression

ISO

Folic Acid results in decreased expression of CRY1 mRNA

NCBI chr 7:20,417,526...20,481,791
Ensembl chr 7:20,417,107...20,481,822

G

cryptochrome circadian regulator 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CRY2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CRY2 gene

PMID:20938992 PMID:22206623

NCBI chr 3:98,830,479...98,860,437
Ensembl chr 3:98,830,483...98,860,447

G

crystallin, alpha B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CRYAB mRNA

NCBI chr 8:59,989,885...59,995,532
Ensembl chr 8:59,989,814...59,995,528

G

crystallin, beta B3

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CRYBB3 mRNA

NCBI chr12:49,217,554...49,222,565
Ensembl chr12:49,217,554...49,222,565

G

crystallin beta-gamma domain containing 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CRYBG1 mRNA

NCBI chr20:49,007,673...49,204,040
Ensembl chr20:49,007,929...49,204,047

G

crystallin beta-gamma domain containing 3

decreases expression

ISO

Folic Acid results in decreased expression of CRYBG3 mRNA

NCBI chr11:54,218,399...54,330,962
Ensembl chr11:54,208,444...54,330,960

G

crystallin, lambda 1

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CRYL1 mRNA
Folic Acid results in decreased expression of CRYL1 mRNA

PMID:22206623 PMID:25629700

NCBI chr15:35,542,628...35,661,563
Ensembl chr15:35,542,628...35,661,563

G

crystallin, mu

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CRYM mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CRYM mRNA

PMID:20938992 PMID:22206623

NCBI chr 1:183,991,752...184,006,923
Ensembl chr 1:183,991,745...184,006,962

G

crystallin zeta

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CRYZ mRNA

NCBI chr 2:246,211,707...246,239,472
Ensembl chr 2:246,211,156...246,239,470

G

crystallin zeta like 1

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CRYZL1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CRYZL1 gene
Folic Acid results in decreased expression of CRYZL1 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr11:44,419,099...44,464,366
Ensembl chr11:44,419,103...44,463,793

G

cysteine sulfinic acid decarboxylase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CSAD mRNA

NCBI chr 7:135,187,175...135,216,495
Ensembl chr 7:135,187,175...135,215,581

G

cold shock domain containing C2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CSDC2 mRNA

NCBI chr 7:115,332,134...115,346,599
Ensembl chr 7:115,332,128...115,346,596

G

cold shock domain containing E1

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CSDE1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CSDE1 gene
Folic Acid results in decreased expression of CSDE1 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr 2:193,234,546...193,271,301
Ensembl chr 2:193,243,526...193,271,301

G

chromosome segregation 1 like

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CSE1L mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CSE1L gene
Folic Acid results in decreased expression of CSE1L mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr 3:176,060,183...176,097,909
Ensembl chr 3:176,060,215...176,108,734

G

colony stimulating factor 1

multiple interactions
decreases expression

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CSF1 mRNA]
Folic Acid results in decreased expression of CSF1 mRNA

PMID:22206623 PMID:28752528

NCBI chr 2:198,065,400...198,084,774
Ensembl chr 2:198,065,405...198,084,468

G

colony stimulating factor 2 receptor subunit alpha

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CSF2RA mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CSF2RA mRNA

PMID:20938992 PMID:22206623

NCBI chr14:113,219...118,808
Ensembl chr14:113,225...118,117

G

colony stimulating factor 2 receptor subunit beta

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CSF2RB mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CSF2RB2 mRNA
Folic Acid results in decreased expression of CSF2RB2 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr 7:111,756,950...111,782,089
Ensembl chr 7:111,757,405...111,784,654

G

colony stimulating factor 3 receptor

decreases expression

ISO

Folic Acid results in decreased expression of CSF3R mRNA

NCBI chr 5:143,583,126...143,604,382
Ensembl chr 5:143,583,213...143,602,411

G

chondroitin sulfate N-acetylgalactosaminyltransferase 2

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of CSGALNACT2 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CSGALNACT2 mRNA

PMID:22206623 PMID:25629700

NCBI chr 4:152,944,154...152,981,237
Ensembl chr 4:152,950,028...152,981,220

G

casein kappa

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CSN3 mRNA; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CSN3 mRNA]
Folic Acid results in decreased expression of CSN3 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr14:20,433,277...20,439,830
Ensembl chr14:20,433,277...20,439,832

G

casein kinase 1, alpha 1

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CSNK1A1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CSNK1A1 gene
Folic Acid results in decreased expression of CSNK1A1 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr18:57,285,156...57,320,540
Ensembl chr18:57,287,412...57,320,538

G

casein kinase 1, delta

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CSNK1D gene

NCBI chr10:106,713,497...106,754,953
Ensembl chr10:106,694,279...106,754,953

G

casein kinase 1, epsilon

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CSNK1E mRNA

NCBI chr 7:112,863,726...112,887,338
Ensembl chr 7:112,863,731...112,884,101

G

casein kinase 1, gamma 1

decreases expression

ISO

Folic Acid results in decreased expression of CSNK1G1 mRNA

NCBI chr 8:75,334,751...75,472,339
Ensembl chr 8:75,334,895...75,467,515

G

casein kinase 1, gamma 2

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CSNK1G2 mRNA]

NCBI chr 7:9,727,430...9,746,341
Ensembl chr 7:9,727,431...9,745,741

G

casein kinase 1, gamma 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CSNK1G3 mRNA

NCBI chr18:49,497,839...49,584,828
Ensembl chr18:49,497,839...49,584,828

G

casein kinase 2 alpha 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CSNK2A1 mRNA

NCBI chr 3:161,170,295...161,217,073
Ensembl chr 3:161,170,405...161,215,698

G

casein kinase 2 alpha 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CSNK2A2 mRNA

NCBI chr19:9,562,340...9,602,136
Ensembl chr19:9,562,321...9,602,136

G

casein kinase 2 beta

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CSNK2B mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CSNK2B gene

PMID:20938992 PMID:22206623

NCBI chr20:3,704,833...3,709,999
Ensembl chr20:3,704,904...3,710,525

G

chondroitin sulfate proteoglycan 5

decreases expression

ISO

Folic Acid results in decreased expression of CSPG5 mRNA

NCBI chr 8:119,098,932...119,113,191
Ensembl chr 8:119,098,925...119,143,907

G

centrosome and spindle pole associated protein 1

multiple interactions
decreases expression

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CSPP1 mRNA]
Folic Acid results in decreased expression of CSPP1 mRNA

PMID:22206623 PMID:25629700

NCBI chr 5:13,860,072...13,975,299
Ensembl chr 5:13,860,072...13,975,321

G

cysteine and serine rich nuclear protein 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of AXUD1 mRNA
Folic Acid results in decreased expression of CSRNP1 mRNA

PMID:20938992 PMID:25629700

NCBI chr 8:128,582,364...128,594,163
Ensembl chr 8:128,582,365...128,588,469

G

cysteine and serine rich nuclear protein 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CSRNP2 gene

NCBI chr 7:133,473,027...133,488,868
Ensembl chr 7:133,473,027...133,488,868

G

cysteine and serine rich nuclear protein 3

decreases expression

ISO

Folic Acid results in decreased expression of CSRNP3 mRNA

NCBI chr 3:70,906,587...71,102,596
Ensembl chr 3:70,906,380...71,094,009

G

cysteine and glycine-rich protein 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CSRP1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CSRP1 mRNA

PMID:20938992 PMID:22206623

NCBI chr13:49,709,928...49,731,141
Ensembl chr13:49,709,914...49,731,139

G

cysteine and glycine-rich protein 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CSRP2 mRNA

NCBI chr 7:48,235,415...48,254,049
Ensembl chr 7:48,235,383...48,266,238

G

cystatin C

increases expression
multiple interactions

ISO

Folic Acid results in increased expression of CST3 protein
6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride inhibits the reaction [Folic Acid results in increased expression of CST3 protein]; 6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride promotes the reaction [pyrazolanthrone inhibits the reaction [Folic Acid results in increased expression of CST3 protein]]; [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CST3 mRNA; pyrazolanthrone inhibits the reaction [Folic Acid results in increased expression of CST3 protein]; pyrazolanthrone promotes the reaction [6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride inhibits the reaction [Folic Acid results in increased expression of CST3 protein]]

PMID:22206623 PMID:31447676

NCBI chr 3:156,790,061...156,794,116
Ensembl chr 3:156,790,079...156,793,937

G

cystatin 8

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CST8 mRNA

NCBI chr 3:156,697,776...156,704,413
Ensembl chr 3:156,697,767...156,724,636

G

cystatin B

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CSTB mRNA

NCBI chr20:10,245,157...10,247,199
Ensembl chr20:10,245,158...10,247,199

G

cleavage stimulation factor subunit 1

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CSTF1 mRNA
Folic Acid results in decreased expression of CSTF1 mRNA

PMID:22206623 PMID:25629700

NCBI chr 3:181,562,953...181,574,727
Ensembl chr 3:181,562,955...181,574,727

G

cleavage stimulation factor subunit 2

decreases expression

ISO

Folic Acid results in decreased expression of CSTF2 mRNA

NCBI chr X:101,546,809...101,572,760
Ensembl chr X:101,546,819...101,572,764

G

cleavage stimulation factor subunit 2, tau variant

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CSTF2T mRNA

NCBI chr 1:238,366,042...238,369,608
Ensembl chr 1:238,365,912...238,369,749

G

cleavage stimulation factor subunit 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CSTF3 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CSTF3 gene

PMID:20938992 PMID:22206623

NCBI chr 3:111,421,291...111,492,539
Ensembl chr 3:111,421,234...111,497,046

G

C-terminal binding protein 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CTBP2 mRNA; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CTBP2 mRNA]

PMID:20938992 PMID:22206623

NCBI chr 1:197,208,536...197,348,802
Ensembl chr 1:197,212,133...197,254,261

G

chitobiase

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CTBS gene

NCBI chr 2:238,000,800...238,015,368
Ensembl chr 2:238,000,842...238,015,475

G

CCCTC-binding factor

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CTCF mRNA

NCBI chr19:50,431,478...50,481,013
Ensembl chr19:50,431,689...50,481,012

G

CTD nuclear envelope phosphatase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CTDNEP1 mRNA

NCBI chr10:55,203,047...55,212,469
Ensembl chr10:55,203,543...55,212,852

G

CTD small phosphatase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CTDSP1 mRNA

NCBI chr 9:83,422,755...83,428,411
Ensembl chr 9:83,423,051...83,428,412

G

CTD small phosphatase like

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CTDSPL mRNA
Folic Acid results in decreased expression of CTDSPL mRNA

PMID:22206623 PMID:25629700

NCBI chr 8:127,520,478...127,644,999
Ensembl chr 8:127,520,499...127,644,999

G

cystathionine gamma-lyase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CTH mRNA; [Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in decreased expression of CTH mRNA; Folic Acid inhibits the reaction [AGT protein results in decreased expression of CTH mRNA]; Folic Acid inhibits the reaction [AGT protein results in decreased expression of CTH protein]

PMID:22206623 PMID:24386282 PMID:29127188

NCBI chr 2:249,634,731...249,661,066
Ensembl chr 2:249,634,731...249,661,066

G

collagen triple helix repeat containing 1

decreases expression

ISO

Folic Acid results in decreased expression of CTHRC1 mRNA

NCBI chr 7:72,007,372...72,017,654
Ensembl chr 7:72,007,372...72,017,654

G

cap binding complex dependent translation initiation factor

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CTIF mRNA

NCBI chr18:71,331,222...71,602,493
Ensembl chr18:71,307,314...71,602,492

G

catenin alpha 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CTNNA1 mRNA

NCBI chr18:27,002,330...27,135,009
Ensembl chr18:26,999,820...27,135,007

G

catenin alpha 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CTNNA2 mRNA

NCBI chr 4:110,852,265...112,001,351
Ensembl chr 4:110,852,265...112,001,365

G

catenin beta 1

affects expression
decreases expression
multiple interactions

ISO

Folic Acid affects the expression of CTNNB1 mRNA
Folic Acid deficiency results in decreased expression of CTNNB1 protein
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CTNNB1 mRNA; [Folic Acid co-treated with sodium arsenite] results in increased methylation of CTNNB1 mRNA

PMID:16361273 PMID:22206623 PMID:22959928 PMID:28639913

NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662

G

catenin, beta-interacting protein 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CTNNBIP1 mRNA

NCBI chr 5:165,245,019...165,293,994
Ensembl chr 5:165,245,098...165,293,991

G

catenin, beta like 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CTNNBL1 mRNA

NCBI chr 3:166,807,899...166,968,932
Ensembl chr 3:166,807,858...166,968,931

G

catenin delta 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CTNND1 mRNA

NCBI chr 3:90,090,025...90,141,247
Ensembl chr 3:90,090,564...90,141,189

G

cystinosin, lysosomal cystine transporter

decreases expression

ISO

Folic Acid results in decreased expression of CTNS mRNA

NCBI chr10:58,300,069...58,315,725
Ensembl chr10:58,299,967...58,321,661

G

CTP synthase 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CTPS1 mRNA; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CTPS1 mRNA]

PMID:20938992 PMID:22206623

NCBI chr 5:139,372,349...139,440,441
Ensembl chr 5:139,410,249...139,440,465

G

CTP synthase 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CTPS2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CTPS2 mRNA

PMID:20938992 PMID:22206623

NCBI chr X:35,277,658...35,418,505
Ensembl chr X:35,277,658...35,418,505

G

CTR9 homolog, Paf1/RNA polymerase II complex component

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CTR9 mRNA]

NCBI chr 1:174,571,952...174,601,974
Ensembl chr 1:174,571,928...174,602,130

G

chymotrypsin-like

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CTRB1 mRNA
Folic Acid results in decreased expression of CTRB1 mRNA

PMID:22206623 PMID:25629700

NCBI chr19:50,737,078...50,740,659
Ensembl chr19:50,737,079...50,738,979

G

cathepsin 7

decreases expression

ISO

Folic Acid results in decreased expression of CTS7 mRNA

NCBI chr17:3,393,930...3,430,291
Ensembl chr17:3,393,930...3,399,070

G

cathepsin A

increases expression
multiple interactions

ISO

Folic Acid results in increased expression of CTSA mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CTSA mRNA

PMID:22206623 PMID:25629700

NCBI chr 3:173,988,443...173,994,320
Ensembl chr 3:173,988,460...173,995,539

G

cathepsin B

decreases expression
multiple interactions

ISO
EXP

Folic Acid results in decreased expression of CTSB mRNA
Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CTSB mRNA]
[Folic Acid deficiency co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of CTSB protein

PMID:19566968 PMID:22206623 PMID:25629700

NCBI chr15:41,565,607...41,586,479
Ensembl chr15:41,565,611...41,586,478

G

cathepsin C

affects expression
decreases expression
multiple interactions

ISO

Folic Acid affects the expression of CTSC mRNA
Folic Acid results in decreased expression of CTSC mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CTSC mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CTSC gene

PMID:17320366 PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr 1:151,440,860...151,472,430
Ensembl chr 1:151,441,032...151,474,082

G

cathepsin D

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CTSD mRNA; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CTSD mRNA]

PMID:20938992 PMID:22206623

NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821

G

cathepsin F

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CTSF mRNA

NCBI chr 1:211,582,169...211,587,917
Ensembl chr 1:211,582,098...211,587,916

G

cathepsin K

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CTSK mRNA
Folic Acid results in decreased expression of CTSK mRNA

PMID:20938992 PMID:25629700

NCBI chr 2:185,747,548...185,758,512
Ensembl chr 2:185,747,165...185,765,582

G

cathepsin L

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CTSL mRNA

NCBI chr17:770,104...776,266
Ensembl chr17:770,093...777,113

G

cathepsin S

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CTSS mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CTSS mRNA

PMID:20938992 PMID:22206623

NCBI chr 2:185,775,316...185,803,440
Ensembl chr 2:185,775,296...185,803,440

G

cortactin

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CTTN mRNA

NCBI chr 1:209,029,048...209,064,577
Ensembl chr 1:209,029,048...209,058,211

G

cortactin binding protein 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CTTNBP2 mRNA

NCBI chr 4:47,766,867...47,930,598
Ensembl chr 4:47,766,870...47,930,540

G

CTTNBP2 N-terminal like

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CTTNBP2NL mRNA

NCBI chr 2:195,196,318...195,244,792
Ensembl chr 2:195,196,318...195,243,181

G

cytosolic thiouridylase subunit 1

decreases expression

ISO

Folic Acid results in decreased expression of CTU1 mRNA

NCBI chr 1:103,251,983...103,257,778
Ensembl chr 1:103,251,995...103,257,775

G

cytosolic thiouridylase subunit 2

increases expression
multiple interactions

ISO

Folic Acid results in increased expression of CTU2 mRNA
Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CTU2 mRNA]

PMID:22206623 PMID:25629700

NCBI chr19:67,447,762...67,453,169
Ensembl chr19:67,447,487...67,453,163

G

cortexin 1

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CTXN1 mRNA]

NCBI chr12:7,408,308...7,409,919
Ensembl chr12:7,408,309...7,409,919

G

cortexin 3

increases expression
multiple interactions

ISO

Folic Acid results in increased expression of CTXN3 mRNA
[Folic Acid co-treated with Ethanol] results in decreased expression of CTXN3 mRNA

PMID:25566775 PMID:25629700

NCBI chr18:53,129,505...53,138,694
Ensembl chr18:53,129,489...53,138,693

G

CUE domain containing 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CUEDC1 mRNA

NCBI chr10:73,389,798...73,484,914
Ensembl chr10:73,389,841...73,483,749

G

CUE domain containing 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CUEDC2 mRNA

NCBI chr 1:255,133,479...255,142,016
Ensembl chr 1:255,133,421...255,141,956

G

cullin 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CUL1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CUL1 gene

PMID:20938992 PMID:22206623

NCBI chr 4:77,551,781...77,634,210
Ensembl chr 4:77,551,787...77,621,760

G

cullin 2

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of CUL2 mRNA
Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CUL2 mRNA]

PMID:22206623 PMID:25629700

NCBI chr17:58,864,274...58,905,447
Ensembl chr17:58,864,274...58,905,132

G

cullin 3

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CUL3 mRNA
Folic Acid results in decreased expression of CUL3 mRNA

PMID:21867686 PMID:22206623 PMID:25629700

NCBI chr 9:89,040,987...89,118,775
Ensembl chr 9:89,040,987...89,118,427

G

cullin 4A

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CUL4A mRNA; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CUL4A mRNA]
Folic Acid results in decreased expression of CUL4A mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr16:83,086,688...83,124,503
Ensembl chr16:83,086,921...83,124,457

G

cullin 4B

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CUL4B mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CUL4B gene
Folic Acid results in decreased expression of CUL4B mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr X:122,154,332...122,192,299
Ensembl chr X:122,154,332...122,192,299

G

cullin 7

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CUL7 mRNA

NCBI chr 9:21,816,703...21,830,344
Ensembl chr 9:21,816,703...21,830,344

G

cut-like homeobox 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CUX1 gene
Folic Acid results in decreased expression of CUX1 mRNA

PMID:20938992 PMID:25629700

NCBI chr12:25,728,393...26,062,497
Ensembl chr12:25,743,733...26,062,497

G

cut-like homeobox 2

decreases expression

ISO

Folic Acid results in decreased expression of CUX2 mRNA

NCBI chr12:40,168,402...40,368,303
Ensembl chr12:40,149,292...40,366,528

G

CWC15 spliceosome-associated protein

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CWC15 mRNA

NCBI chr 8:19,586,900...19,597,817
Ensembl chr 2:77,747,121...77,747,856
Ensembl chr 8:77,747,121...77,747,856

G

CWC22 spliceosome associated protein

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of CWC22 mRNA
Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CWC22 mRNA]

PMID:22206623 PMID:25629700

NCBI chr 3:83,222,400...83,271,427
Ensembl chr 3:83,209,194...83,271,513

G

CWC27 spliceosome associated cyclophilin

decreases expression

ISO

Folic Acid results in decreased expression of CWC27 mRNA

NCBI chr 2:37,498,462...37,709,691
Ensembl chr 2:37,498,468...37,709,355

G

C-X3-C motif chemokine ligand 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CX3CL1 mRNA

NCBI chr19:10,233,326...10,244,856
Ensembl chr19:10,233,329...10,242,999

G

C-X3-C motif chemokine receptor 1

multiple interactions

ISO

[Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CX3CR1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CX3CR1 mRNA

PMID:20938992 PMID:23439872

NCBI chr 8:128,661,294...128,679,048
Ensembl chr 8:128,654,833...128,685,983

G

CXADR, Ig-like cell adhesion molecule

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CXADR gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CXADR mRNA]

PMID:20938992 PMID:22206623

NCBI chr11:30,469,778...30,516,990
Ensembl chr11:30,469,526...30,516,988

G

C-X-C motif chemokine ligand 11

decreases expression

ISO

Folic Acid results in decreased expression of CXCL11 mRNA

NCBI chr14:15,973,728...15,976,503
Ensembl chr14:15,973,720...15,976,567

G

C-X-C motif chemokine ligand 12

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CXCL12 mRNA

NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627

G

C-X-C motif chemokine ligand 14

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CXCL14 mRNA

NCBI chr17:8,323,150...8,331,176
Ensembl chr17:8,323,143...8,331,172

G

C-X-C motif chemokine ligand 16

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CXCL16 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CXCL16 mRNA

PMID:20938992 PMID:22206623

NCBI chr10:55,665,355...55,669,950
Ensembl chr10:55,664,742...55,670,226

G

C-X-C motif chemokine ligand 3

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CXCL1 mRNA
Folic Acid results in increased expression of CXCL1 mRNA

PMID:20938992 PMID:34619300

NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624

G

C-X-C motif chemokine ligand 6

decreases expression

ISO

Folic Acid results in decreased expression of CXCL6 mRNA

NCBI chr14:17,594,959...17,596,417
Ensembl chr14:17,594,959...17,596,417

G

C-X-C motif chemokine receptor 4

multiple interactions
decreases expression
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CXCR4 mRNA
Folic Acid results in decreased expression of CXCR4 mRNA
Folic Acid results in increased expression of CXCR4 mRNA

PMID:20938992 PMID:25629700 PMID:28752528

NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459

G

CXXC finger protein 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CXXC1 mRNA

NCBI chr18:70,088,407...70,093,786
Ensembl chr18:70,088,460...70,093,778

G

cytochrome b561 family, member D1

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CYB561D1 mRNA]

NCBI chr 2:198,523,031...198,525,671
Ensembl chr 2:198,523,031...198,525,676

G

cytochrome b561 family, member D2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CYB561D2 mRNA

NCBI chr 8:117,091,844...117,094,434
Ensembl chr 8:117,091,845...117,094,366

G

cytochrome b5 type B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CYB5B mRNA

NCBI chr19:51,972,611...52,006,477
Ensembl chr19:51,972,547...52,026,980

G

cytochrome b5 reductase 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CYB5R1 mRNA; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CYB5R1 mRNA]

PMID:20938992 PMID:22206623

NCBI chr13:48,401,061...48,407,466
Ensembl chr13:48,399,106...48,407,465

G

cytochrome b5 reductase 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CYB5R3 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CYB5R3 mRNA

PMID:20938992 PMID:22206623

NCBI chr 7:116,186,729...116,204,290
Ensembl chr 7:116,186,729...116,204,306

G

cytochrome b5 reductase 4

decreases expression

ISO

Folic Acid results in decreased expression of CYB5R4 mRNA

NCBI chr 8:96,860,415...96,925,789
Ensembl chr 8:96,861,090...96,926,094

G

cytochrome b-245 alpha chain

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CYBA mRNA
Folic Acid results in decreased expression of CYBA mRNA

PMID:20938992 PMID:25629700

NCBI chr19:67,396,143...67,404,214
Ensembl chr19:67,396,143...67,404,214

G

cytochrome b-245 beta chain

multiple interactions
affects response to substance
increases response to substance

ISO

CYBB mutant form inhibits the reaction [[Folic Acid deficiency results in increased abundance of Homocysteine] which results in decreased expression of CDH3 mRNA]; CYBB mutant form inhibits the reaction [[Folic Acid deficiency results in increased abundance of Homocysteine] which results in decreased expression of CDH3 protein]; CYBB mutant form inhibits the reaction [[Folic Acid deficiency results in increased abundance of Homocysteine] which results in decreased expression of TJP1 mRNA]; CYBB mutant form inhibits the reaction [[Folic Acid deficiency results in increased abundance of Homocysteine] which results in increased expression of ACTA2 mRNA]; CYBB mutant form inhibits the reaction [[Folic Acid deficiency results in increased abundance of Homocysteine] which results in increased expression of ACTA2 protein]; CYBB mutant form inhibits the reaction [[Folic Acid deficiency results in increased abundance of Homocysteine] which results in increased expression of S100A4 mRNA]; CYBB mutant form inhibits the reaction [[Folic Acid deficiency results in increased abundance of Homocysteine] which results in increased expression of S100A4 protein]; CYBB mutant form inhibits the reaction [Folic Acid deficiency results in decreased expression of CDH3 protein]; CYBB mutant form inhibits the reaction [Folic Acid deficiency results in decreased expression of NPHS2 protein]; CYBB mutant form inhibits the reaction [Folic Acid deficiency results in increased expression of ACTA2 protein]; CYBB mutant form inhibits the reaction [Folic Acid deficiency results in increased expression of S100A4 protein]; CYBB mutant form inhibits the reaction [Folic Acid deficiency results in increased secretion of ALB protein]; CYBB protein affects the reaction [Folic Acid deficiency results in increased chemical synthesis of Superoxides]; CYBB protein mutant form inhibits the reaction [[Folic Acid deficiency results in increased abundance of Homocysteine] which results in decreased expression of NPHS1 mRNA]; CYBB protein mutant form inhibits the reaction [[Folic Acid deficiency results in increased abundance of Homocysteine] which results in decreased expression of NPHS2 mRNA]; CYBB protein mutant form inhibits the reaction [[Folic Acid deficiency results in increased abundance of Homocysteine] which results in increased expression of DES mRNA]; Folic Acid inhibits the reaction [AGT protein results in increased expression of CYBB protein]
CYBB protein affects the susceptibility to Folic Acid deficiency
CYBB results in increased susceptibility to Folic Acid

PMID:20116427 PMID:21647593 PMID:24386282

NCBI chr X:16,030,596...16,065,065
Ensembl chr X:16,030,596...16,065,065

G

cytochrome b-245 chaperone 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CYBC1 mRNA

NCBI chr10:106,997,018...107,003,895
Ensembl chr10:106,997,023...107,003,841

G

cytochrome c-1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CYC1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CYC1 gene

PMID:20938992 PMID:22206623

NCBI chr 7:109,947,750...109,950,142
Ensembl chr 7:109,947,766...109,950,657

G

cytochrome c, somatic

multiple interactions

ISO
EXP

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CYCS mRNA; Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in increased expression of CYCS protein]
Folic Acid inhibits the reaction [Nicotine results in increased expression of CYCS protein]

PMID:22206623 PMID:29068127 PMID:29972271

NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816
Ensembl chr18:80,982,668...80,984,816

G

cytoplasmic FMR1 interacting protein 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CYFIP1 gene

NCBI chr 1:115,842,754...115,935,163
Ensembl chr 1:115,846,661...115,951,292

G

cytoplasmic FMR1 interacting protein 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CYFIP2 mRNA

NCBI chr10:31,122,653...31,242,440
Ensembl chr10:31,122,653...31,242,440

G

CYLD lysine 63 deubiquitinase

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CYLD gene

NCBI chr19:34,487,491...34,547,311
Ensembl chr19:34,488,583...34,547,118

G

cytochrome P450, family 17, subfamily a, polypeptide 1

decreases expression

ISO

Folic Acid results in decreased expression of CYP17A1 mRNA

NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974

G

cytochrome P450, family 1, subfamily a, polypeptide 2

multiple interactions

ISO

[Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in decreased expression of CYP1A2 mRNA

NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149

G

cytochrome P450, family 1, subfamily b, polypeptide 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CYP1B1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CYP1B1 gene
Folic Acid results in decreased expression of CYP1B1 mRNA

PMID:20938992 PMID:25629700

NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142

G

cytochrome P450, family 20, subfamily a, polypeptide 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CYP20A1 mRNA

NCBI chr 9:69,249,841...69,299,146
Ensembl chr 9:69,249,844...69,299,291

G

cytochrome P450, family 26, subfamily a, polypeptide 1

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of CYP26A1 mRNA

NCBI chr 1:244,883,822...244,887,657
Ensembl chr 1:244,883,752...244,887,657

G

cytochrome P450, family 26, subfamily b, polypeptide 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CYP26B1 gene
Folic Acid results in decreased expression of CYP26B1 mRNA

PMID:20938992 PMID:25629700

NCBI chr 4:118,599,356...118,616,176
Ensembl chr 4:118,599,356...118,616,176

G

cytochrome P450, family 27, subfamily a, polypeptide 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CYP27A1 mRNA

NCBI chr 9:83,712,402...83,743,222
Ensembl chr 9:83,713,293...83,743,215

G

cytochrome P450, family 2, subfamily b, polypeptide 2

multiple interactions

ISO

[Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of CYP2B13 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CYP2B13 mRNA; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CYP2B13 mRNA]

PMID:20938992 PMID:22206623 PMID:29127188

NCBI chr 1:90,722,243...90,736,272

G

cytochrome P450, family 2, subfamily b, polypeptide 3

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of CYP2B10 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CYP2B10 mRNA

PMID:22872676 PMID:33549593

NCBI chr 1:90,780,468...90,859,852

G

cytochrome P450, family 2, subfamily c, polypeptide 24

increases expression
multiple interactions

ISO

Folic Acid results in increased expression of CYP2C55 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CYP2C55 mRNA; [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of CYP2C55 mRNA

PMID:22206623 PMID:25629700 PMID:33549593

NCBI chr 1:246,286,341...246,348,607
Ensembl chr 1:246,286,341...246,348,607

G

cytochrome P450, family 2, subfamily C, polypeptide 6

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CYP2C29 mRNA

NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798

G

cytochrome P450, family 2, subfamily c, polypeptide 66

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CYP2C66 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CYP2C66 mRNA

PMID:20938992 PMID:22206623

NCBI chr 1:246,490,888...246,582,199
Ensembl chr 1:248,272,336...248,309,323

G

cytochrome P450, family 2, subfamily d, polypeptide 4

decreases expression

ISO

Folic Acid results in decreased expression of CYP2D22 mRNA

NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837

G

cytochrome P450, family 2, subfamily e, polypeptide 1

multiple interactions
decreases expression

ISO

[Betaine co-treated with Choline co-treated with Folic Acid co-treated with Methionine co-treated with Vitamin B 12 co-treated with Zinc Sulfate] inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein]; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CYP2E1 mRNA; icariin inhibits the reaction [Folic Acid results in decreased expression of CYP2E1 protein]

PMID:20118189 PMID:22872676 PMID:38272249

NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495

G

cytochrome P450, family 39, subfamily a, polypeptide 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CYP39A1 mRNA

NCBI chr 9:24,727,817...24,804,060
Ensembl chr 9:24,727,817...24,804,060

G

cytochrome P450, family 3, subfamily a, polypeptide 9

decreases expression

ISO

Folic Acid results in decreased expression of CYP3A13 mRNA

NCBI chr12:21,919,955...21,960,160
Ensembl chr12:21,919,940...21,960,154

G

cytochrome P450, family 46, subfamily a, polypeptide 1

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CYP46A1 mRNA]

NCBI chr 6:133,011,948...133,039,167
Ensembl chr 6:133,011,989...133,041,971

G

cytochrome P450, family 4, subfamily b, polypeptide 1

decreases expression

ISO

Folic Acid results in decreased expression of CYP4B1 mRNA

NCBI chr 5:134,375,807...134,413,635
Ensembl chr 5:134,375,807...134,393,116

G

cytochrome P450, family 4, subfamily f, polypeptide 1

multiple interactions

ISO

[Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in decreased expression of CYP4F14 mRNA

NCBI chr 7:12,661,357...12,672,952
Ensembl chr 7:12,661,359...12,672,612

G

cytochrome P450, family 4, subfamily f, polypeptide 18

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CYP4F18 mRNA

NCBI chr16:17,797,558...17,838,958
Ensembl chr16:17,740,001...17,838,958

G

cytochrome P450, family 4, subfamily f, polypeptide 6

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CYP4F16 mRNA

NCBI chr 7:12,680,799...12,708,378
Ensembl chr 7:12,680,806...12,708,402

G

cytochrome P450, family 4, subfamily v, polypeptide 3

decreases expression

ISO

Folic Acid results in decreased expression of CYP4V3 mRNA

NCBI chr16:53,650,978...53,675,916
Ensembl chr16:53,650,569...53,676,746

G

cytochrome P450, family 4, subfamily x, polypeptide 1

decreases expression

ISO

Folic Acid results in decreased expression of CYP4X1 mRNA

NCBI chr 5:133,888,439...133,923,254
Ensembl chr 5:133,888,439...133,919,642

G

cytochrome P450, family 51

decreases expression

ISO

Folic Acid results in decreased expression of CYP51 mRNA

NCBI chr 4:30,991,693...31,010,147
Ensembl chr 4:30,991,613...31,010,450

G

cytochrome P450 family 7 subfamily B member 1

multiple interactions

ISO

[Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in decreased expression of CYP7B1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CYP7B1 mRNA

PMID:22872676 PMID:29127188

NCBI chr 2:102,419,011...102,586,047
Ensembl chr 2:102,419,011...102,451,804

G

cell cycle regulator of NHEJ

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CYREN mRNA

NCBI chr 4:64,514,477...64,519,896
Ensembl chr 4:64,514,477...64,518,742

G

CYFIP related Rac1 interactor A

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CYRIA mRNA
Folic Acid results in decreased expression of FAM49A mRNA

PMID:20938992 PMID:25629700

NCBI chr 6:40,774,165...40,883,005
Ensembl chr 6:40,774,171...40,881,860

G

cystin 1

decreases expression

ISO

Folic Acid results in decreased expression of CYS1 mRNA

NCBI chr 6:47,029,440...47,046,671
Ensembl chr 6:47,028,461...47,046,671

G

cysteinyl leukotriene receptor 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CYSLTR1 mRNA

NCBI chr X:75,734,281...75,762,873
Ensembl chr X:75,734,270...75,763,050

G

cytohesin 2

increases expression
multiple interactions

ISO

Folic Acid results in increased expression of CYTH2 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CYTH2 mRNA

PMID:22206623 PMID:25629700

NCBI chr 1:105,419,631...105,427,542
Ensembl chr 1:105,419,631...105,427,542

G

cytohesin 3

decreases expression

ISO

Folic Acid results in decreased expression of CYTH3 mRNA

NCBI chr12:15,953,781...16,076,584
Ensembl chr12:15,953,791...16,047,506

G

cytohesin 4

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CYTH4 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CYTH4 mRNA

PMID:20938992 PMID:22206623

NCBI chr 7:112,032,711...112,057,204
Ensembl chr 7:112,032,775...112,057,204

G

cytohesin 1 interacting protein

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CYTIP mRNA

NCBI chr 3:63,106,895...63,183,769
Ensembl chr 3:63,107,607...63,134,832

G

cytokine like 1

decreases expression

ISO

Folic Acid results in decreased expression of CYTL1 mRNA

NCBI chr14:77,278,635...77,283,645
Ensembl chr14:77,278,636...77,283,645

G

CXXC motif containing zinc binding protein

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CZIB mRNA

NCBI chr 5:127,875,408...127,885,100
Ensembl chr 5:127,877,173...127,886,538

G

D-2-hydroxyglutarate dehydrogenase

decreases expression

ISO

Folic Acid results in decreased expression of D2HGDH mRNA

NCBI chr 9:101,796,287...101,815,727
Ensembl chr 9:101,797,895...101,815,727

G

DAB adaptor protein 1

decreases expression

ISO

Folic Acid results in decreased expression of DAB1 mRNA

NCBI chr 5:123,621,510...124,742,585
Ensembl chr 5:124,369,415...124,742,584

G

dachshund family transcription factor 1

decreases expression

ISO

Folic Acid results in decreased expression of DACH1 mRNA

NCBI chr15:80,936,063...81,317,746
Ensembl chr15:80,936,063...81,317,627

G

dachshund family transcription factor 2

decreases expression

ISO

Folic Acid results in decreased expression of DACH2 mRNA

NCBI chr X:82,644,374...83,210,181
Ensembl chr X:82,644,128...83,210,000

G

dishevelled-binding antagonist of beta-catenin 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of DACT1 gene
Folic Acid results in decreased expression of DACT1 mRNA

PMID:20938992 PMID:25629700

NCBI chr 6:95,526,645...95,538,625
Ensembl chr 6:95,526,690...95,551,053

G

dishevelled-binding antagonist of beta-catenin 2

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of DACT2 gene
Folic Acid results in increased expression of DACT2 mRNA

PMID:20938992 PMID:25629700

NCBI chr 1:63,854,182...63,864,153
Ensembl chr 1:63,854,182...63,864,255

G

defender against cell death 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DAD1 mRNA

NCBI chr15:31,647,326...31,667,159
Ensembl chr15:31,647,326...31,667,287

G

dystroglycan 1

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of DAG1 mRNA]

NCBI chr 8:117,769,517...117,834,347
Ensembl chr 8:117,769,517...117,782,199

G

diacylglycerol lipase, beta

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DAGLB mRNA

NCBI chr12:16,173,345...16,215,777
Ensembl chr12:16,173,345...16,215,758

G

death-associated protein

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of DAP mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DAP mRNA

PMID:22206623 PMID:25629700

NCBI chr 2:83,910,113...83,962,673
Ensembl chr 2:83,910,060...83,962,673

G

death associated protein 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DAP3 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DAP3 mRNA

PMID:20938992 PMID:22206623

NCBI chr 2:176,617,151...176,645,293
Ensembl chr 2:176,617,155...176,644,270

G

death-associated protein kinase 2

multiple interactions
increases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DAPK2 mRNA
Folic Acid results in increased expression of DAPK2 mRNA

PMID:22206623 PMID:25629700

NCBI chr 8:75,601,621...75,720,619
Ensembl chr 8:75,601,634...75,720,617

G

death-associated protein kinase 3

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DAPK3 gene

NCBI chr 7:9,174,903...9,183,272
Ensembl chr 7:9,174,904...9,183,272

G

dual adaptor of phosphotyrosine and 3-phosphoinositides 1

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DAPP1 mRNA
Folic Acid results in increased expression of DAPP1 mRNA

PMID:20938992 PMID:25629700

NCBI chr 2:229,099,319...229,148,868
Ensembl chr 2:229,099,319...229,148,843

G

aspartyl-tRNA synthetase 1

decreases expression

ISO

Folic Acid results in decreased expression of DARS1 mRNA

NCBI chr13:42,410,351...42,465,467
Ensembl chr13:42,379,162...42,465,467

G

death-domain associated protein

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DAXX mRNA

NCBI chr20:4,971,973...4,978,062
Ensembl chr20:4,971,941...4,977,720

G

DAZ associated protein 1

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of DAZAP1 mRNA]

NCBI chr 7:10,074,342...10,098,810
Ensembl chr 7:10,074,849...10,095,599

G

DAZ associated protein 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DAZAP2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DAZAP2 gene

PMID:20938992 PMID:22206623

NCBI chr 7:133,593,503...133,599,044
Ensembl chr 7:133,593,512...133,599,047

G

DBF4B-CDC7 kinase regulatory subunit

decreases expression

ISO

Folic Acid results in decreased expression of DBF4B mRNA

NCBI chr10:88,209,913...88,219,336

G

dopamine beta-hydroxylase

increases expression
multiple interactions

ISO

Folic Acid results in increased expression of DBH mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DBH mRNA

PMID:22206623 PMID:25006883

NCBI chr 3:30,886,313...30,903,313
Ensembl chr 3:30,886,328...30,903,316

G

diazepam binding inhibitor

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DBI mRNA

NCBI chr13:33,794,231...33,802,632
Ensembl chr13:33,759,845...33,821,450

G

dysbindin domain containing 1

increases expression

ISO

Folic Acid results in increased expression of DBNDD1 mRNA

NCBI chr19:68,447,641...68,461,272
Ensembl chr19:68,447,635...68,458,797

G

dysbindin domain containing 2

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DBNDD2 mRNA; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of DBNDD2 mRNA]
Folic Acid results in increased expression of DBNDD2 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr 3:173,634,551...173,639,999

G

drebrin-like

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of DBNL mRNA]

NCBI chr14:84,880,085...84,895,122
Ensembl chr14:84,880,142...84,897,133

G

dihydrolipoamide branched chain transacylase E2

decreases expression

ISO

Folic Acid results in decreased expression of DBT mRNA

NCBI chr 2:207,166,660...207,195,528
Ensembl chr 2:207,166,652...207,195,525

G

developing brain homeobox 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DBX1 gene

NCBI chr 1:108,484,846...108,490,381
Ensembl chr 1:108,484,863...108,490,381

G

DDB1 and CUL4 associated factor 10

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of WDR32 gene

NCBI chr 5:64,402,307...64,442,839
Ensembl chr 5:64,403,451...64,440,614

G

DDB1 and CUL4 associated factor 11

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DCAF11 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of DCAF11 gene

PMID:20938992 PMID:22206623

NCBI chr15:33,015,370...33,027,407
Ensembl chr15:33,016,762...33,027,672

G

DDB1 and CUL4 associated factor 12

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DCAF12 mRNA

NCBI chr 5:61,256,353...61,278,155
Ensembl chr 5:61,256,353...61,278,119

G

DDB1 and CUL4 associated factor 12-like 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of DCAF12L1 mRNA

NCBI chr X:128,572,969...128,576,588
Ensembl chr X:128,572,811...128,577,222

G

DDB1 and CUL4 associated factor 12-like 2

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of DCAF12L2 mRNA
Folic Acid results in increased expression of DCAF12L2 mRNA

PMID:20938992 PMID:25629700

NCBI chr X:128,167,040...128,169,829
Ensembl chr X:128,167,040...128,169,829

G

DDB1 and CUL4 associated factor 17

multiple interactions
decreases expression

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of DCAF17 mRNA]
Folic Acid results in decreased expression of DCAF17 mRNA

PMID:22206623 PMID:25629700

NCBI chr 3:76,271,503...76,303,321
Ensembl chr 3:76,271,519...76,303,320

G

DDB1 and CUL4 associated factor 4

decreases expression

ISO

Folic Acid results in decreased expression of DCAF4 mRNA

NCBI chr 6:108,885,970...108,912,116
Ensembl chr 6:108,885,932...108,912,110

G

DDB1 and CUL4 associated factor 6

decreases expression

ISO

Folic Acid results in decreased expression of DCAF6 mRNA

NCBI chr13:80,159,282...80,260,510
Ensembl chr13:80,159,321...80,260,510

G

DDB1 and CUL4 associated factor 7

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DCAF7 mRNA

NCBI chr10:91,473,900...91,496,080
Ensembl chr10:91,473,900...91,496,080

G

DDB1 and CUL4 associated factor 8

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of DCAF8 gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of DCAF8 mRNA]

PMID:20938992 PMID:22206623

NCBI chr13:87,141,940...87,199,859
Ensembl chr13:87,142,525...87,202,099

G

dephospho-CoA kinase domain containing

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of DCAKD mRNA]

NCBI chr10:88,457,829...88,489,011
Ensembl chr10:88,457,829...88,480,118

G

discoidin, CUB and LCCL domain containing 1

decreases expression

ISO

Folic Acid results in decreased expression of DCBLD1 mRNA

NCBI chr20:32,161,241...32,254,391
Ensembl chr20:32,161,254...32,281,176

G

doublecortin domain containing 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DCDC2A gene; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DCDC2A mRNA

NCBI chr17:40,274,009...40,459,757
Ensembl chr17:40,274,009...40,458,790

G

doublecortin domain containing 2B

decreases expression

ISO

Folic Acid results in decreased expression of DCDC2B mRNA

NCBI chr 5:147,235,365...147,241,776
Ensembl chr 5:147,219,366...147,241,232

G

dachsous cadherin-related 2

decreases expression

ISO

Folic Acid results in decreased expression of DCHS2 mRNA

NCBI chr 2:170,775,818...170,983,844
Ensembl chr 2:170,776,682...170,981,770

G

deoxycytidine kinase

decreases expression

ISO

Folic Acid results in decreased expression of DCK mRNA

NCBI chr14:19,589,298...19,610,326
Ensembl chr14:19,589,298...19,610,326

G

doublecortin-like kinase 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DCLK1 mRNA
Folic Acid results in decreased expression of DCLK1 mRNA

PMID:20938992 PMID:25629700

NCBI chr 2:141,567,215...141,861,088
Ensembl chr 2:141,571,983...141,861,090

G

doublecortin-like kinase 2

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DCLK2 mRNA
Folic Acid results in increased expression of DCLK2 mRNA

PMID:20938992 PMID:25629700

NCBI chr 2:174,506,660...174,636,353
Ensembl chr 2:174,506,660...174,636,192

G

DNA cross-link repair 1C

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of DCLRE1C mRNA
Folic Acid results in decreased expression of DCLRE1C mRNA

PMID:20938992 PMID:25629700

NCBI chr17:79,684,988...79,718,399
Ensembl chr17:79,678,698...79,718,734

G

decorin

multiple interactions
affects expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DCN mRNA
Folic Acid affects the expression of DCN mRNA

PMID:20938992 PMID:27293554

NCBI chr 7:34,167,973...34,208,004
Ensembl chr 7:34,163,011...34,218,926

G

decapping mRNA 1A

decreases expression

ISO

Folic Acid results in decreased expression of DCP1A mRNA

NCBI chr16:5,663,437...5,708,623
Ensembl chr16:5,663,203...5,708,618

G

decapping mRNA 1B

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of DCP1B mRNA]

NCBI chr 4:154,030,181...154,068,038
Ensembl chr 4:154,030,690...154,068,035

G

decapping enzyme, scavenger

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DCPS mRNA

NCBI chr 8:41,729,507...41,782,222
Ensembl chr 8:41,724,563...41,782,222

G

DC-STAMP domain containing 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DCST1 gene

NCBI chr 2:177,063,083...177,079,914
Ensembl chr 2:177,063,083...177,079,927

G

dendrocyte expressed seven transmembrane protein

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DCSTAMP mRNA

NCBI chr 7:72,692,364...72,706,983
Ensembl chr 7:72,671,477...72,707,009

G

dCMP deaminase

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DCTD mRNA

NCBI chr16:50,799,699...50,831,398
Ensembl chr16:50,787,875...50,831,186

G

dynactin subunit 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DCTN1 mRNA

NCBI chr 4:117,228,722...117,261,528
Ensembl chr 4:117,219,349...117,261,528

G

dynactin subunit 2

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of DCTN2 mRNA]

NCBI chr 7:64,977,338...64,992,875
Ensembl chr 7:64,977,363...64,992,873

G

dynactin subunit 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DCTN3 mRNA

NCBI chr 5:61,676,950...61,684,958
Ensembl chr 5:61,676,950...61,684,903

G

dynactin subunit 4

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of DCTN4 mRNA]

NCBI chr18:56,251,187...56,279,844
Ensembl chr18:56,252,780...56,279,842

G

dynactin subunit 5

increases expression

ISO

Folic Acid results in increased expression of DCTN5 mRNA

NCBI chr 1:186,120,415...186,137,146
Ensembl chr 1:186,119,913...186,137,146

G

dynactin subunit 6

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DCTN6 mRNA

NCBI chr16:64,780,759...64,799,766
Ensembl chr16:64,780,735...64,801,060

G

dCTP pyrophosphatase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DCTPP1 mRNA

NCBI chr 1:191,307,933...191,311,326
Ensembl chr 1:191,307,935...191,313,405

G

defective in cullin neddylation 1 domain containing 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DCUN1D1 mRNA

NCBI chr 2:120,649,445...120,700,879
Ensembl chr 2:120,649,445...120,700,870

G

defective in cullin neddylation 1 domain containing 4

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of DCUN1D4 mRNA

NCBI chr14:35,006,792...35,087,285
Ensembl chr14:35,006,792...35,088,520

G

defective in cullin neddylation 1 domain containing 5

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DCUN1D5 mRNA

NCBI chr 8:12,697,160...12,718,242
Ensembl chr 8:12,697,127...12,718,991

G

doublecortin

increases expression

ISO

Folic Acid results in increased expression of DCX protein

NCBI chr X:112,227,455...112,370,291
Ensembl chr X:112,227,455...112,304,161

G

dicarbonyl and L-xylulose reductase

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DCXR mRNA
Folic Acid results in decreased expression of DCXR mRNA

PMID:22206623 PMID:25629700

NCBI chr10:106,504,730...106,506,619

G

DET1 and DDB1 associated 1

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of DDA1 mRNA]

NCBI chr16:18,190,280...18,197,914
Ensembl chr16:18,190,306...18,197,913

G

dimethylarginine dimethylaminohydrolase 1

multiple interactions
decreases expression

ISO

Folic Acid inhibits the reaction [AGT protein results in increased expression of DDAH1 mRNA]; Folic Acid inhibits the reaction [AGT protein results in increased expression of DDAH1 protein]
Folic Acid results in decreased expression of DDAH1 mRNA

PMID:24386282 PMID:25629700

NCBI chr 2:237,327,812...237,460,624
Ensembl chr 2:237,327,766...237,460,626

G

damage-specific DNA binding protein 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DDB1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DDB1 gene

PMID:20938992 PMID:22206623

NCBI chr 1:216,677,810...216,703,605
Ensembl chr 1:216,677,810...216,703,596

G

dopa decarboxylase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DDC mRNA

NCBI chr14:90,592,304...90,682,830
Ensembl chr14:90,592,304...90,682,806

G

DDHD domain containing 2

decreases expression

ISO

Folic Acid results in decreased expression of DDHD2 mRNA

NCBI chr16:73,022,136...73,051,746
Ensembl chr16:73,022,193...73,051,745

G

DNA damage inducible 1 homolog 2

decreases expression

ISO

Folic Acid results in decreased expression of DDI2 mRNA

NCBI chr 5:159,272,625...159,318,365
Ensembl chr 5:159,272,625...159,318,310

G

DNA-damage inducible transcript 3

multiple interactions
decreases expression

ISO
EXP

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DDIT3 mRNA; [Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DDIT3 protein; [Vitamin B 6 co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in increased expression of DDIT3 protein]
Folic Acid results in decreased expression of DDIT3 mRNA
[Folic Acid deficiency co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of DDIT3 mRNA
[Folic Acid co-treated with Methyl Methanesulfonate] results in increased expression of DDIT3 mRNA; [Folic Acid deficiency co-treated with Methotrexate] results in increased expression of DDIT3 mRNA; [Vitamin B 6 co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in increased expression of DDIT3 protein]; Folic Acid inhibits the reaction [Camptothecin results in decreased expression of DDIT3 mRNA]; Folic Acid inhibits the reaction [Doxorubicin results in decreased expression of DDIT3 mRNA]

PMID:19566968 PMID:22206623 PMID:23439872 PMID:24657277 PMID:25629700 More...

NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509

G

DNA-damage-inducible transcript 4

multiple interactions

ISO

[Folic Acid deficiency co-treated with succinylsulfathiazole] results in decreased expression of DDIT4 protein; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DDIT4 gene
[Ethanol co-treated with Folic Acid] results in increased expression of DDIT4 mRNA

PMID:20938992 PMID:23378141 PMID:33957263

NCBI chr20:28,434,938...28,437,037
Ensembl chr20:28,434,944...28,437,037

G

DNA-damage-inducible transcript 4-like

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of DDIT4L; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DDIT4L gene; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DDIT4L mRNA

NCBI chr 2:228,800,831...228,804,478
Ensembl chr 2:228,801,705...228,806,225

G

dendrin

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of DDN gene

NCBI chr 7:131,832,270...131,836,252
Ensembl chr 7:131,832,271...131,836,294

G

dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DDOST mRNA

NCBI chr 5:155,805,612...155,812,728
Ensembl chr 5:155,805,454...155,813,121

G

discoidin domain receptor tyrosine kinase 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DDR1 mRNA

NCBI chr20:3,047,269...3,069,277
Ensembl chr20:3,050,375...3,069,276

G

D-dopachrome tautomerase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DDT mRNA

NCBI chr20:12,883,025...12,886,121

G

DEAD-box helicase 10

decreases expression

ISO

Folic Acid results in decreased expression of DDX10 mRNA

NCBI chr 8:62,384,876...62,539,585
Ensembl chr 8:62,384,876...62,539,585

G

DEAD-box helicase 17

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DDX17 mRNA

NCBI chr 7:112,971,522...112,989,747
Ensembl chr 7:112,971,523...112,989,747

G

DEAD-box helicase 18

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DDX18 mRNA

NCBI chr13:35,282,391...35,296,038
Ensembl chr13:35,282,467...35,295,972

G

DEAD-box helicase 19A

decreases expression

ISO

Folic Acid results in decreased expression of DDX19A mRNA

NCBI chr19:55,851,854...55,872,209
Ensembl chr19:55,851,854...55,872,209

G

DEAD-box helicase 20

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of DDX20 gene

NCBI chr 2:195,847,105...195,859,989
Ensembl chr 2:195,847,105...195,855,461

G

DEAD-box helicase 28

decreases expression

ISO

Folic Acid results in decreased expression of DDX28 mRNA

NCBI chr19:50,819,643...50,821,573
Ensembl chr19:50,819,313...50,822,803

G

DEAD-box helicase 31

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DDX31 mRNA

NCBI chr 3:32,570,725...32,635,446
Ensembl chr 3:32,571,020...32,636,954

G

DExD-box helicase 39A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DDX39A mRNA

NCBI chr19:41,323,465...41,331,413
Ensembl chr19:41,322,836...41,332,306

G

DExD-box helicase 39B

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of DDX39B mRNA]

NCBI chr20:3,577,200...3,589,651
Ensembl chr20:3,576,734...3,589,651

G

DEAD-box helicase 3, X-linked

increases expression
multiple interactions

ISO

Folic Acid results in increased expression of DDX3X mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DDX3X mRNA

PMID:22206623 PMID:26547318

NCBI chr X:12,152,346...12,165,983
Ensembl chr X:12,152,346...12,165,983

G

DEAD box helicase 3, Y-linked

increases expression

ISO

Folic Acid results in increased expression of DDX3Y mRNA

NCBI chr Y:1,190,042...1,210,699
Ensembl chr Y:1,191,242...1,210,650

G

DEAD-box helicase 41

multiple interactions
decreases expression

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of DDX41 mRNA]
Folic Acid results in decreased expression of DDX41 mRNA

PMID:22206623 PMID:25629700

NCBI chr17:9,108,030...9,113,562
Ensembl chr17:9,108,074...9,113,561

G

DEAD-box helicase 47

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DDX47 mRNA

NCBI chr 4:169,577,013...169,589,473
Ensembl chr 4:169,577,003...169,590,474

G

DEAD-box helicase 49

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of DDX49 gene

NCBI chr16:19,159,353...19,167,003
Ensembl chr16:19,159,087...19,167,580

G

DEAD-box helicase 5

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DDX5 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DDX5 gene

PMID:20938992 PMID:22206623

NCBI chr10:92,224,393...92,231,928
Ensembl chr10:92,224,395...92,231,300

G

DExD-box helicase 50

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DDX50 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DDX50 gene

PMID:20938992 PMID:22206623

NCBI chr20:31,104,354...31,133,652
Ensembl chr20:31,104,354...31,133,652

G

DEAD-box helicase 51

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DDX51 mRNA

NCBI chr12:51,671,078...51,675,900
Ensembl chr12:51,671,078...51,676,099

G

DExD-box helicase 52

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DDX52 mRNA

NCBI chr10:69,322,062...69,344,856
Ensembl chr10:69,322,114...69,428,714

G

DEAD-box helicase 54

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DDX54 mRNA

NCBI chr12:41,595,298...41,610,560
Ensembl chr12:41,595,555...41,611,053

G

DEAD-box helicase 55

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DDX55 gene
Folic Acid results in decreased expression of DDX55 mRNA

PMID:20938992 PMID:25629700

NCBI chr12:37,695,444...37,711,198
Ensembl chr12:37,695,444...37,711,198

G

DEAD-box helicase 56

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DDX56 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of DDX56 gene

PMID:20938992 PMID:22206623

NCBI chr14:85,325,942...85,336,262
Ensembl chr14:85,325,942...85,336,262

G

DEAD-box helicase 59

increases expression

ISO

Folic Acid results in increased expression of DDX59 mRNA

NCBI chr13:50,427,940...50,452,893
Ensembl chr13:50,427,936...50,453,208

G

DEAD-box helicase 6

decreases expression

ISO

Folic Acid results in decreased expression of DDX6 mRNA

NCBI chr 8:53,827,661...53,864,538
Ensembl chr 8:53,827,835...53,860,977

G

2,4-dienoyl-CoA reductase 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DECR1 gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of DECR1 mRNA]

PMID:20938992 PMID:22206623

NCBI chr 5:34,208,195...34,236,074
Ensembl chr 5:34,208,195...34,236,033

G

death effector domain-containing

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of DEDD gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of DEDD mRNA]

PMID:20938992 PMID:22206623

NCBI chr13:86,286,341...86,301,789
Ensembl chr13:86,288,350...86,302,446

G

death effector domain containing 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DEDD2 mRNA

NCBI chr 1:89,916,906...89,934,663
Ensembl chr 1:89,919,524...89,936,804

G

DEF6 guanine nucleotide exchange factor

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DEF6 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DEF6 mRNA

PMID:20938992 PMID:22206623

NCBI chr20:6,270,323...6,291,724
Ensembl chr20:6,269,357...6,291,771

G

defensin beta 14

increases expression

ISO

Folic Acid results in increased expression of DEFB14 mRNA

NCBI chr16:77,365,892...77,369,668
Ensembl chr16:77,365,892...77,366,880

G

defensin beta 15

decreases expression

ISO

Folic Acid results in decreased expression of DEFB106B mRNA

NCBI chr16:76,843,661...76,846,359
Ensembl chr16:76,843,661...76,846,359

G

defensin beta 21

decreases expression

ISO

Folic Acid results in decreased expression of DEFB118 mRNA

NCBI chr 3:161,503,090...161,504,507
Ensembl chr 3:161,503,090...161,504,507

G

defensin beta 26

increases expression

ISO

Folic Acid results in increased expression of DEFB26 mRNA

NCBI chr 3:161,437,500...161,441,234
Ensembl chr 3:161,437,500...161,441,234

G

defensin beta 28

decreases expression

ISO

Folic Acid results in decreased expression of DEFB28 mRNA

NCBI chr 3:161,448,316...161,454,051
Ensembl chr 3:161,448,091...161,451,409

G

defensin beta 30

increases expression

ISO

Folic Acid results in increased expression of DEFB30 mRNA

NCBI chr15:41,470,697...41,474,458
Ensembl chr15:41,470,697...41,474,458

G

defensin beta 42

increases expression

ISO

Folic Acid results in increased expression of DEFB48 mRNA

NCBI chr15:41,410,651...41,417,610
Ensembl chr15:41,410,651...41,417,610

G

delta(4)-desaturase, sphingolipid 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DEGS2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DEGS2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of DEGS2 gene

PMID:20938992 PMID:22206623

NCBI chr 6:133,360,449...133,377,677
Ensembl chr 6:133,360,457...133,364,422

G

DEK proto-oncogene

affects expression

ISO

Folic Acid affects the expression of DEK mRNA

NCBI chr17:17,786,989...17,809,096
Ensembl chr17:17,787,139...17,810,122

G

DAP3 binding cell death enhancer 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DELE1 mRNA

NCBI chr18:30,325,369...30,349,285
Ensembl chr18:30,336,308...30,349,938

G

DENN domain containing 10

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DENND10 mRNA

NCBI chr 1:269,937,023...269,960,506
Ensembl chr 1:269,936,895...269,962,853

G

DENN domain containing 1A

decreases expression

ISO

Folic Acid results in decreased expression of DENND1A mRNA

NCBI chr 3:41,974,502...42,461,816
Ensembl chr 3:41,974,502...42,461,886

G

DENN domain containing 1C

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DENND1C mRNA
Folic Acid results in decreased expression of DENND1C mRNA

PMID:20938992 PMID:25629700

NCBI chr 9:1,991,035...2,003,330
Ensembl chr 9:1,991,039...2,003,151

G

DENN domain containing 2B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DENND2B mRNA

NCBI chr 1:172,978,895...173,129,623
Ensembl chr 1:172,978,895...173,129,810

G

DENN domain containing 2D

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of DENND2D gene
Folic Acid results in decreased expression of DENND2D mRNA

PMID:20938992 PMID:25629700

NCBI chr 2:196,661,465...196,680,505
Ensembl chr 2:196,661,345...196,682,397

G

DENN domain containing 3

increases expression

ISO

Folic Acid results in increased expression of DENND3 mRNA

NCBI chr 7:107,304,860...107,362,573
Ensembl chr 7:107,220,192...107,362,573

G

DENN domain containing 4A

decreases expression

ISO

Folic Acid results in decreased expression of DENND4A mRNA

NCBI chr 8:74,218,131...74,331,543
Ensembl chr 8:74,218,191...74,331,542

G

DENN domain containing 4C

decreases expression

ISO

Folic Acid results in decreased expression of DENND4C mRNA

NCBI chr 5:106,316,942...106,421,484
Ensembl chr 5:106,318,281...106,415,489

G

DENN domain containing 5A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DENND5A mRNA

NCBI chr 1:173,362,959...173,428,973
Ensembl chr 1:173,362,959...173,428,926

G

DENN domain containing 5B

increases expression

ISO

Folic Acid results in increased expression of DENND5B mRNA

NCBI chr 4:183,688,039...183,821,012
Ensembl chr 4:183,692,227...183,820,508

G

DENN domain containing 6A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DENND6A mRNA

NCBI chr16:1,843,803...1,892,165
Ensembl chr16:1,843,752...1,892,163

G

density regulated reinitiation and release factor

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of DENR; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DENR gene; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DENR mRNA
Folic Acid results in decreased expression of DENR mRNA

PMID:20938992 PMID:25629700

NCBI chr12:38,323,433...38,346,207
Ensembl chr12:38,323,445...38,344,797

G

DEP domain containing 1

multiple interactions

ISO

[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of DEPDC1 mRNA

NCBI chr 2:251,343,250...251,376,709
Ensembl chr 2:251,343,281...251,376,709

G

DEP domain containing 5, GATOR1 subcomplex subunit

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DEPDC5 mRNA
Folic Acid results in decreased expression of DEPDC5 mRNA

PMID:22206623 PMID:25629700

NCBI chr14:81,956,777...82,087,392
Ensembl chr14:81,956,777...82,087,246

G

DEPP autophagy regulator 1

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of DEPP1 mRNA

NCBI chr 4:151,583,105...151,585,455
Ensembl chr 4:151,581,502...151,586,233

G

DEP domain containing MTOR-interacting protein

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of DEPTOR mRNA
Folic Acid results in increased expression of DEPTOR mRNA

PMID:20938992 PMID:25629700

NCBI chr 7:88,404,745...88,574,065
Ensembl chr 7:88,404,620...88,574,041

G

deoxyribose-phosphate aldolase

decreases expression

ISO

Folic Acid results in decreased expression of DERA mRNA

NCBI chr 4:172,394,971...172,473,746
Ensembl chr 4:172,394,962...172,490,142

G

derlin 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DERL1 mRNA

NCBI chr 7:91,293,963...91,316,639
Ensembl chr 7:91,258,382...91,316,678

G

derlin 2

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of DERL2 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DERL2 mRNA

PMID:22206623 PMID:25629700

NCBI chr10:56,226,340...56,238,038
Ensembl chr10:56,226,219...56,237,993

G

derlin 3

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of DERL3 mRNA]

NCBI chr20:12,753,926...12,766,478
Ensembl chr20:12,762,981...12,766,477

G

desmin

increases expression
multiple interactions

ISO

Folic Acid deficiency results in increased expression of DES protein
[Folic Acid deficiency results in increased abundance of Homocysteine] which results in increased expression of DES mRNA; CYBB protein mutant form inhibits the reaction [[Folic Acid deficiency results in increased abundance of Homocysteine] which results in increased expression of DES mRNA]

PMID:20116427 PMID:21893018

NCBI chr 9:84,299,626...84,307,344
Ensembl chr 9:84,298,447...84,307,347

G

desumoylating isopeptidase 1

decreases expression

ISO

Folic Acid results in decreased expression of DESI1 mRNA

NCBI chr 7:115,401,613...115,422,974
Ensembl chr 7:115,401,624...115,423,172

G

DET1 partner of COP1 E3 ubiquitin ligase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DET1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DET1 mRNA

PMID:20938992 PMID:22206623

NCBI chr 1:142,159,120...142,175,366
Ensembl chr 1:142,127,876...142,175,336

G

deuterosome assembly protein 1

decreases expression

ISO

Folic Acid results in decreased expression of DEUP1 mRNA

NCBI chr 8:20,661,687...20,724,083
Ensembl chr 8:20,661,689...20,723,585

G

Dexi homolog

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DEXI mRNA

NCBI chr10:5,632,400...5,645,653
Ensembl chr10:5,632,961...5,645,648

G

DNA fragmentation factor subunit alpha

decreases expression

ISO

Folic Acid results in decreased expression of DFFA mRNA

NCBI chr 5:164,823,807...164,836,729
Ensembl chr 5:164,823,807...164,836,728

G

diacylglycerol O-acyltransferase 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DGAT1 gene
Folic Acid results in decreased expression of DGAT1 mRNA

PMID:20938992 PMID:25629700

NCBI chr 7:110,104,514...110,119,091
Ensembl chr 7:110,098,906...110,115,016

G

DiGeorge syndrome critical region gene 2

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of DGCR2 mRNA]

NCBI chr11:96,598,247...96,648,791
Ensembl chr11:96,597,197...96,648,786

G

diacylglycerol kinase, beta

decreases expression

ISO

Folic Acid results in decreased expression of DGKB mRNA

NCBI chr 6:60,368,101...61,124,420
Ensembl chr 6:60,368,519...61,124,420

G

diacylglycerol kinase, delta

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DGKD mRNA

NCBI chr 9:95,964,507...96,055,160
Ensembl chr 9:95,964,148...96,055,160

G

diacylglycerol kinase epsilon

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DGKE gene

NCBI chr10:74,348,931...74,374,509
Ensembl chr10:74,350,246...74,374,478

G

diacylglycerol kinase, gamma

decreases expression

ISO

Folic Acid results in decreased expression of DGKG mRNA

NCBI chr11:91,888,957...92,083,715
Ensembl chr11:91,888,782...92,082,105

G

diacylglycerol kinase, eta

decreases expression

ISO

Folic Acid results in decreased expression of DGKH mRNA

NCBI chr15:60,390,279...60,559,777
Ensembl chr15:60,402,004...60,560,218

G

diacylglycerol kinase, iota

decreases expression

ISO

Folic Acid results in decreased expression of DGKI mRNA

NCBI chr 4:66,377,897...66,839,790
Ensembl chr 4:66,387,126...66,990,832

G

deoxyguanosine kinase

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of DGUOK mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DGUOK mRNA

PMID:22206623 PMID:25629700

NCBI chr 4:117,544,784...117,572,414
Ensembl chr 4:117,544,773...117,572,414

G

7-dehydrocholesterol reductase

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of DHCR7 mRNA
Folic Acid results in decreased expression of DHCR7 mRNA

PMID:20938992 PMID:25629700

NCBI chr 1:208,444,434...208,460,408
Ensembl chr 1:208,444,434...208,461,382

G

dehydrodolichyl diphosphate synthase subunit

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of DHDDS mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DHDDS mRNA

PMID:22206623 PMID:25629700

NCBI chr 5:151,482,139...151,508,248
Ensembl chr 5:151,481,429...151,508,129

G

dihydrofolate reductase

multiple interactions
increases expression
affects expression
decreases abundance

ISO
EXP

[Folic Acid affects the susceptibility to Pemetrexed] which affects the expression of DHFR mRNA; [Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of DHFR mRNA; Leucovorin inhibits the reaction [DHFR gene mutant form results in decreased abundance of Folic Acid]
Folic Acid results in increased expression of DHFR mRNA
Folic Acid inhibits the reaction [Methotrexate results in decreased expression of DHFR mRNA]
[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of DHFR mRNA
Folic Acid affects the expression of DHFR mRNA

PMID:17311948 PMID:20938992 PMID:21310277 PMID:22975265 PMID:24657277 More...

NCBI chr 2:25,320,895...25,346,004

G

dihydroorotate dehydrogenase

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of DHODH mRNA]

NCBI chr19:54,460,636...54,483,049
Ensembl chr19:54,468,690...54,514,496

G

deoxyhypusine synthase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DHPS mRNA

NCBI chr19:39,987,328...39,991,418
Ensembl chr19:39,987,324...39,991,432

G

dehydrogenase/reductase 1

decreases expression

ISO

Folic Acid results in decreased expression of DHRS1 mRNA

NCBI chr15:33,206,449...33,213,776
Ensembl chr15:33,206,451...33,213,734

G

dehydrogenase/reductase 7

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DHRS7 mRNA

NCBI chr 6:97,068,149...97,083,744
Ensembl chr 6:97,068,149...97,083,744

G

dehydrogenase/reductase 7C

decreases expression

ISO

Folic Acid results in decreased expression of DHRS7C mRNA

NCBI chr10:52,994,205...53,012,281
Ensembl chr10:52,994,205...53,012,281

G

dehydrogenase/reductase 9

multiple interactions

ISO

[Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of DHRS9 mRNA

NCBI chr 3:74,553,357...74,579,535
Ensembl chr 3:74,555,606...74,581,376

G

dehydrogenase/reductase X-linked

decreases expression

ISO

Folic Acid results in decreased expression of DHRSX mRNA

NCBI chr12:21,413,563...21,418,319
Ensembl chr12:21,413,575...21,418,319

G

dehydrogenase E1 and transketolase domain containing 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of DHTKD1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DHTKD1 gene

NCBI chr17:77,242,512...77,316,074
Ensembl chr17:77,264,514...77,316,071

G

DExH-box helicase 29

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of DHX29 gene

NCBI chr 2:46,293,901...46,344,652
Ensembl chr 2:46,293,677...46,344,948

G

DExH-box helicase 30

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DHX30 mRNA

NCBI chr 8:118,943,186...118,975,319
Ensembl chr 8:118,943,187...118,975,592

G

DEAH-box helicase 32 (putative)

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DHX32 mRNA

NCBI chr 1:197,954,503...198,013,779
Ensembl chr 1:197,954,503...198,007,489

G

DEAH-box helicase 33

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DHX33 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DHX33 gene

PMID:20938992 PMID:22206623

NCBI chr10:56,206,680...56,223,189
Ensembl chr10:56,206,680...56,223,143

G

DEAH-box helicase 35

decreases expression

ISO

Folic Acid results in decreased expression of DHX35 mRNA

NCBI chr 3:167,869,971...167,927,300
Ensembl chr 3:167,870,055...167,927,300

G

DEAH-box helicase 36

decreases expression

ISO

Folic Acid results in decreased expression of DHX36 mRNA

NCBI chr 2:149,006,089...149,044,192
Ensembl chr 2:149,006,089...149,044,191

G

DEAH-box helicase 37

decreases expression

ISO

Folic Acid results in decreased expression of DHX37 mRNA

NCBI chr12:36,856,119...36,876,245
Ensembl chr12:36,849,701...36,876,240

G

DEAH-box helicase 40

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DHX40 mRNA
Folic Acid results in decreased expression of DHX40 mRNA

PMID:22206623 PMID:25629700

NCBI chr10:72,081,867...72,118,792
Ensembl chr10:72,081,867...72,118,958

G

DEXH-box helicase 58

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of DHX58 mRNA]

NCBI chr10:86,120,677...86,132,095
Ensembl chr10:86,120,677...86,131,844

G

DEAH-box helicase 8

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DHX8 mRNA

NCBI chr10:87,167,861...87,204,426
Ensembl chr10:87,168,062...87,205,875

G

diablo, IAP-binding mitochondrial protein

increases expression
multiple interactions

ISO

Folic Acid results in increased expression of DIABLO mRNA; Folic Acid results in increased expression of DIABLO protein
Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of DIABLO mRNA]

PMID:12969128 PMID:22206623

NCBI chr12:38,716,668...38,731,285
Ensembl chr12:38,716,668...38,731,265

G

diaphanous-related formin 1

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of DIAP1 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DIAPH1 mRNA

PMID:22206623 PMID:25629700

NCBI chr18:29,920,889...30,020,280
Ensembl chr18:29,920,889...30,020,280

G

diaphanous-related formin 2

decreases expression

ISO

Folic Acid results in decreased expression of DIAP2 mRNA

NCBI chr X:96,700,535...97,528,080
Ensembl chr X:96,700,726...97,528,080

G

dicer 1 ribonuclease III

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DICER1 gene

NCBI chr 6:129,392,298...129,457,252
Ensembl chr 6:129,396,014...129,457,252

G

death inducer-obliterator 1

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DIDO1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DIDO1 gene
Folic Acid results in decreased expression of DIDO1 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr 3:188,150,100...188,203,445
Ensembl chr 3:188,150,100...188,194,823

G

DIM1 rRNA methyltransferase and ribosome maturation factor

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DIMT1 mRNA

NCBI chr 2:40,076,622...40,101,792
Ensembl chr 2:40,076,570...40,101,787

G

iodothyronine deiodinase 3

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DIO3 gene
Folic Acid results in increased expression of DIO3 mRNA

PMID:20938992 PMID:26547318

NCBI chr 6:135,107,072...135,108,933
Ensembl chr 6:135,107,074...135,107,985

G

disco-interacting protein 2 homolog A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DIP2A mRNA

NCBI chr20:12,284,037...12,373,519
Ensembl chr20:12,284,038...12,370,532

G

disco-interacting protein 2 homolog B

decreases expression

ISO

Folic Acid results in decreased expression of DIP2B mRNA

NCBI chr 7:133,053,393...133,231,430
Ensembl chr 7:133,053,401...133,228,874

G

disco-interacting protein 2 homolog C

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of DIP2C mRNA]

NCBI chr17:65,338,711...65,724,111
Ensembl chr17:65,338,711...65,723,344

G

divergent protein kinase domain 1A

decreases expression

ISO

Folic Acid results in decreased expression of FAM69A mRNA

NCBI chr14:1,917,353...1,988,188
Ensembl chr14:1,917,324...1,988,678

G

divergent protein kinase domain 1B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DIPK1B mRNA

NCBI chr 3:29,852,710...29,862,248
Ensembl chr 3:29,853,973...29,862,255

G

DIRAS family GTPase 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DIRAS1 gene

NCBI chr 7:9,338,660...9,343,524
Ensembl chr 7:9,327,335...9,347,881

G

DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DIS3 mRNA

NCBI chr15:82,231,922...82,258,299
Ensembl chr15:82,231,283...82,258,333

G

dispatched RND transporter family member 1

decreases expression

ISO

Folic Acid results in decreased expression of DISP1 mRNA

NCBI chr13:97,252,574...97,398,329
Ensembl chr13:97,252,574...97,398,460

G

dispatched RND transporter family member 2

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of DISP2 gene
Folic Acid results in increased expression of DISP2 mRNA

PMID:20938992 PMID:25629700

NCBI chr 3:126,216,194...126,231,724
Ensembl chr 3:126,216,218...126,231,711

G

dispatched RND transporter family member 3

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DISP3 gene

NCBI chr 5:163,955,160...164,003,980
Ensembl chr 5:163,955,160...164,003,950

G

dyskerin pseudouridine synthase 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of DKC1 gene
Folic Acid results in decreased expression of DKC1 mRNA

PMID:20938992 PMID:25629700

NCBI chr  X:157,751,651...157,757,796
Ensembl chr  Y:380,743...385,405
Ensembl chr  X:380,743...385,405

G

dickkopf WNT signaling pathway inhibitor 1

increases expression
affects expression

ISO

Folic Acid results in increased expression of DKK1 mRNA
Folic Acid affects the expression of DKK1 mRNA

PMID:17320366 PMID:17868486

NCBI chr 1:237,794,969...237,798,650
Ensembl chr 1:237,794,969...237,798,650

G

dickkopf WNT signaling pathway inhibitor 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DKK2 gene

NCBI chr 2:223,242,375...223,334,249
Ensembl chr 2:223,242,377...223,334,724

G

dickkopf WNT signaling pathway inhibitor 3

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of DKK3; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DKK3 gene; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DKK3 mRNA
Folic Acid deficiency results in increased expression of DKK3 mRNA; Folic Acid results in increased expression of DKK3 mRNA

PMID:20938992 PMID:28752528

NCBI chr 1:175,672,834...175,715,867
Ensembl chr 1:175,672,834...175,715,186

G

dihydrolipoamide S-acetyltransferase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DLAT mRNA

NCBI chr 8:59,875,537...59,900,947
Ensembl chr 8:59,868,214...59,900,818
Ensembl chr 1:59,868,214...59,900,818

G

dihydrolipoamide dehydrogenase

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DLD mRNA
Folic Acid results in decreased expression of DLD mRNA

PMID:22206623 PMID:25629700

NCBI chr 6:53,631,686...53,655,059
Ensembl chr 6:53,619,631...53,652,354

G

deleted in lymphocytic leukemia, 7

decreases expression

ISO

Folic Acid results in decreased expression of DLEU7 mRNA

NCBI chr15:40,655,563...40,671,759
Ensembl chr15:40,655,563...40,671,759

G

discs large MAGUK scaffold protein 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DLG1 mRNA

NCBI chr11:82,416,853...82,607,797
Ensembl chr11:82,416,853...82,607,797

G

discs large MAGUK scaffold protein 2

decreases expression

ISO

Folic Acid results in decreased expression of DLG2 mRNA

NCBI chr 1:153,864,545...155,916,238
Ensembl chr 1:153,865,299...155,916,215

G

DLG associated protein 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of DLGAP2; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DLGAP2 gene; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DLGAP2 mRNA

NCBI chr16:81,489,059...82,198,693
Ensembl chr16:81,494,649...82,198,684

G

DLG associated protein 3

increases expression

ISO

Folic Acid results in increased expression of DLGAP3 mRNA

NCBI chr 5:144,776,414...144,847,097
Ensembl chr 5:144,777,295...144,847,097

G

DLG associated protein 4

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DLGAP4 gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of DLGAP4 mRNA]

PMID:20938992 PMID:22206623

NCBI chr 3:165,584,271...165,731,868
Ensembl chr 3:165,584,360...165,730,604

G

DLG associated protein 5

multiple interactions

ISO

[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of DLGAP5 mRNA

NCBI chr15:23,113,678...23,144,281
Ensembl chr15:23,113,678...23,144,176

G

delta like non-canonical Notch ligand 1

multiple interactions

ISO

[Folic Acid co-treated with sodium arsenite] results in decreased methylation of DLK1 mRNA

NCBI chr 6:134,192,491...134,199,779
Ensembl chr 6:134,192,518...134,200,529

G

delta like canonical Notch ligand 1

decreases expression

ISO

Folic Acid results in decreased expression of DLL1 mRNA

NCBI chr 1:64,985,161...64,993,274
Ensembl chr 1:64,985,161...64,993,276

G

delta like canonical Notch ligand 4

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of DLL4 gene
Folic Acid results in increased expression of DLL4 mRNA

PMID:20938992 PMID:25629700

NCBI chr 3:126,770,945...126,780,769
Ensembl chr 3:126,770,794...126,780,763

G

distal-less homeobox 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DLX1 gene

NCBI chr 3:76,763,864...76,768,454
Ensembl chr 3:76,763,500...76,768,447

G

distal-less homeobox 2

decreases expression

ISO

Folic Acid results in decreased expression of DLX2 mRNA

NCBI chr 3:76,777,912...76,781,255
Ensembl chr 3:76,777,912...76,781,255

G

distal-less homeobox 3

decreases expression

ISO

Folic Acid results in decreased expression of DLX3 mRNA

NCBI chr10:80,561,335...80,566,730
Ensembl chr10:80,561,335...80,566,711

G

distal membrane arm assembly component 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DMAC1 mRNA

NCBI chr 5:94,288,900...94,290,053
Ensembl chr 5:94,280,654...94,290,119

G

distal membrane arm assembly component 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DMAC2 mRNA

NCBI chr 1:90,250,262...90,262,592
Ensembl chr 1:90,243,532...90,262,594

G

deleted in malignant brain tumors 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DMBT1 mRNA

NCBI chr 1:195,047,702...195,126,704
Ensembl chr 1:195,047,713...195,126,704

G

dystrophin

decreases expression

ISO

Folic Acid results in decreased expression of DMD mRNA

NCBI chr X:51,070,098...53,437,845
Ensembl chr X:51,070,273...53,437,835

G

dimethylglycine dehydrogenase

increases expression

ISO

Folic Acid results in increased expression of DMGDH mRNA

NCBI chr 2:26,647,540...26,722,496
Ensembl chr 2:26,647,565...26,723,071

G

dermokine

decreases expression

ISO

Folic Acid results in decreased expression of DMKN mRNA

NCBI chr 1:95,140,737...95,158,676
Ensembl chr 1:95,141,620...95,157,439

G

DM1 protein kinase

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of DMPK; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DMPK gene; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DMPK mRNA

NCBI chr 1:87,858,294...87,868,624
Ensembl chr 1:87,858,316...87,868,910

G

doublesex and mab-3 related transcription factor 1

decreases expression

ISO

Folic Acid results in decreased expression of DMRT1 mRNA

NCBI chr 1:232,569,179...232,667,646
Ensembl chr 1:232,569,072...232,668,370

G

DMRT-like family A2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of DMRTA2 gene

NCBI chr 5:130,034,473...130,040,283
Ensembl chr 5:130,034,473...130,040,222

G

DMRT-like family C2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of DMRTC2 gene

NCBI chr 1:89,594,120...89,601,761
Ensembl chr 1:89,594,215...89,601,762

G

DM1 locus, WD repeat containing

increases expression

ISO

Folic Acid results in increased expression of DMWD mRNA

NCBI chr 1:87,850,475...87,857,263
Ensembl chr 1:87,850,604...87,857,624

G

dynein, axonemal, assembly factor 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DNAAF1 gene

NCBI chr19:64,532,859...64,560,942
Ensembl chr19:64,532,860...64,561,435

G

dynein axonemal assembly factor 10

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of DNAAF10 mRNA]

NCBI chr14:95,820,272...95,841,449
Ensembl chr14:95,820,234...95,841,442

G

dynein axonemal assembly factor 19

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCDC103 mRNA

NCBI chr10:88,346,453...88,349,853
Ensembl chr10:88,346,453...88,349,853

G

dynein, axonemal, heavy chain 10

decreases expression

ISO

Folic Acid results in decreased expression of DNAH10 mRNA

NCBI chr12:37,484,444...37,607,810
Ensembl chr12:37,472,813...37,640,860

G

dynein, axonemal, heavy chain 11

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DNAH11 mRNA
[Ethanol co-treated with Folic Acid] results in increased expression of DNAH11 mRNA

PMID:20938992 PMID:23378141

NCBI chr 6:144,982,130...145,298,523
Ensembl chr 6:144,973,797...145,298,692

G

dynein, axonemal, heavy chain 12

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DNAH12 mRNA

NCBI chr16:1,932,776...2,099,391
Ensembl chr16:1,944,752...2,099,373

G

dynein, axonemal, heavy chain 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DNAH2 mRNA

NCBI chr10:54,641,450...54,766,502
Ensembl chr10:54,641,450...54,766,026

G

dynein, axonemal, heavy chain 5

decreases expression

ISO

Folic Acid results in decreased expression of DNAH5 mRNA

NCBI chr 2:80,668,182...80,985,918
Ensembl chr 2:80,668,208...80,985,914

G

dynein, axonemal, heavy chain 7

decreases expression

ISO

Folic Acid results in decreased expression of DNAH7 mRNA

NCBI chr 9:62,454,838...62,760,504
Ensembl chr 9:62,454,838...62,756,730

G

dynein, axonemal, intermediate chain 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DNAI1 mRNA

NCBI chr 5:61,526,079...61,596,806
Ensembl chr 5:61,525,999...61,596,810

G

dynein axonemal intermediate chain 4

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DNAI4 mRNA

NCBI chr 5:123,016,480...123,105,283
Ensembl chr 5:123,016,480...123,105,283

G

DnaJ heat shock protein family (Hsp40) member A2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DNAJA2 mRNA

NCBI chr19:37,671,019...37,689,163
Ensembl chr19:37,670,945...37,690,120

G

DnaJ heat shock protein family (Hsp40) member A4

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DNAJA4 mRNA

NCBI chr 8:63,975,177...63,998,836
Ensembl chr 8:63,981,559...63,998,836

G

DnaJ heat shock protein family (Hsp40) member B11

multiple interactions
increases expression

EXP
ISO

[Folic Acid deficiency co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of DNAJB11 protein; [Methionine deficiency co-treated with Choline deficiency] inhibits the reaction [Folic Acid deficiency results in increased expression of DNAJB11 protein]
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DNAJB11 mRNA

PMID:19566968 PMID:22206623

NCBI chr11:91,656,334...91,672,800
Ensembl chr11:91,656,335...91,672,800

G

DnaJ heat shock protein family (Hsp40) member B2

multiple interactions
decreases expression

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of DNAJB2 mRNA]
Folic Acid results in decreased expression of DNAJB2 mRNA

PMID:22206623 PMID:25629700

NCBI chr 9:84,179,702...84,187,942
Ensembl chr 9:84,179,695...84,187,942

G

DnaJ heat shock protein family (Hsp40) member B5

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DNAJB5 gene

NCBI chr 5:61,972,637...61,981,887
Ensembl chr 5:61,972,706...61,981,860

G

DnaJ heat shock protein family (Hsp40) member B6

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DNAJB6 mRNA

NCBI chr 4:6,010,081...6,232,052
Ensembl chr 4:6,128,070...6,232,005

G

DnaJ heat shock protein family (Hsp40) member B8

increases expression

ISO

Folic Acid results in increased expression of DNAJB8 mRNA

NCBI chr 4:122,239,209...122,242,277
Ensembl chr 4:122,227,595...122,247,526

G

DnaJ heat shock protein family (Hsp40) member B9

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DNAJB9 mRNA
Folic Acid results in decreased expression of DNAJB9 mRNA

PMID:22206623 PMID:25629700

NCBI chr 6:66,997,842...67,007,371
Ensembl chr 6:66,997,842...67,009,344

G

DnaJ heat shock protein family (Hsp40) member C1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DNAJC1 gene

NCBI chr17:85,863,651...86,020,954
Ensembl chr17:85,863,651...86,020,432

G

DnaJ heat shock protein family (Hsp40) member C10

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DNAJC10 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DNAJC10 gene

PMID:20938992 PMID:22206623

NCBI chr 3:85,636,890...85,679,620
Ensembl chr 3:85,639,589...85,689,368

G

DnaJ heat shock protein family (Hsp40) member C11

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DNAJC11 mRNA
Folic Acid results in decreased expression of DNAJC11 mRNA

PMID:20938992 PMID:25629700

NCBI chr 5:167,724,776...167,770,032
Ensembl chr 5:167,724,717...167,770,694

G

DnaJ heat shock protein family (Hsp40) member C12

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DNAJC12 mRNA; icariin inhibits the reaction [Folic Acid results in decreased expression of DNAJC12 protein]

PMID:22206623 PMID:38272249

NCBI chr20:25,245,475...25,266,238
Ensembl chr20:25,222,298...25,266,251

G

DnaJ heat shock protein family (Hsp40) member C13

decreases expression

ISO

Folic Acid results in decreased expression of DNAJC13 mRNA

NCBI chr 8:113,646,573...113,756,104
Ensembl chr 8:113,646,573...113,756,104

G

DnaJ heat shock protein family (Hsp40) member C14

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of DNAJC14 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DNAJC14 mRNA

PMID:22206623 PMID:25629700

NCBI chr 7:1,818,360...1,831,642
Ensembl chr 7:1,820,247...1,831,658

G

DnaJ heat shock protein family (Hsp40) member C15

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DNAJC15 mRNA

NCBI chr15:59,594,314...59,658,862
Ensembl chr15:59,594,314...59,658,987

G

DnaJ heat shock protein family (Hsp40) member C18

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DNAJC18 mRNA

NCBI chr18:27,543,438...27,577,535
Ensembl chr18:27,543,438...27,577,535

G

DnaJ heat shock protein family (Hsp40) member C19

multiple interactions
increases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DNAJC19 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of DNAJC19 mRNA
Folic Acid results in increased expression of DNAJC19 mRNA

PMID:20938992 PMID:21867686 PMID:22206623

NCBI chr 2:118,851,497...118,875,813
Ensembl chr 2:118,869,413...118,873,781

G

DnaJ heat shock protein family (Hsp40) member C21

decreases expression

ISO

Folic Acid results in decreased expression of DNAJC21 mRNA

NCBI chr 2:61,146,669...61,173,908
Ensembl chr 2:61,145,142...61,174,126

G

DnaJ heat shock protein family (Hsp40) member C24

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of DNAJC24 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DNAJC24 mRNA

PMID:22206623 PMID:25629700

NCBI chr 3:112,905,369...112,940,741
Ensembl chr 3:112,904,769...112,940,640

G

DnaJ heat shock protein family (Hsp40) member C3

decreases expression

ISO

Folic Acid results in decreased expression of DNAJC3 mRNA

NCBI chr15:102,432,667...102,475,643
Ensembl chr15:102,432,663...102,475,643

G

DnaJ heat shock protein family (Hsp40) member C30

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DNAJC30 mRNA

NCBI chr12:27,264,861...27,265,940
Ensembl chr12:27,262,802...27,266,169

G

DnaJ heat shock protein family (Hsp40) member C4

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DNAJC4 mRNA

NCBI chr 1:213,607,397...213,611,614
Ensembl chr 1:213,607,399...213,611,729

G

DnaJ heat shock protein family (Hsp40) member C7

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DNAJC7 mRNA

NCBI chr10:86,018,977...86,055,419
Ensembl chr10:86,018,961...86,055,489

G

DnaJ heat shock protein family (Hsp40) member C8

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DNAJC8 mRNA

NCBI chr 5:150,029,064...150,047,115
Ensembl chr 5:150,026,286...150,047,117

G

DnaJ heat shock protein family (Hsp40) member C9

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DNAJC9 mRNA

NCBI chr15:3,970,843...4,003,009
Ensembl chr15:3,970,114...3,977,304

G

dynein, axonemal, light chain 1

decreases expression

ISO

Folic Acid results in decreased expression of DNAL1 mRNA

NCBI chr 6:109,478,941...109,515,201
Ensembl chr 6:109,478,858...109,513,148

G

dynein, axonemal, light chain 4

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DNAL4 mRNA

NCBI chr 7:113,192,807...113,205,665
Ensembl chr20:21,722,009...21,723,262
Ensembl chr 7:21,722,009...21,723,262

G

deoxyribonuclease 1-like 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DNASE1L1 mRNA

NCBI chr X:157,208,230...157,216,812
Ensembl chr X:157,208,230...157,216,711

G

deoxyribonuclease 1L3

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of DNASE1L3 mRNA]

NCBI chr15:19,351,683...19,378,536
Ensembl chr15:19,352,493...19,378,531

G

deoxyribonuclease 2, lysosomal

decreases expression

ISO

Folic Acid results in decreased expression of DNASE2A mRNA

NCBI chr19:40,149,505...40,152,225
Ensembl chr19:40,149,505...40,152,225

G

delta/notch-like EGF repeat containing

decreases expression

ISO

Folic Acid results in decreased expression of DNER mRNA

NCBI chr 9:93,035,108...93,350,568
Ensembl chr 9:93,035,108...93,350,568

G

DNL-type zinc finger

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DNLZ mRNA

NCBI chr 3:29,568,041...29,569,937
Ensembl chr 3:29,568,041...29,569,996

G

dynamin 1

increases expression

ISO

Folic Acid results in increased expression of DNM1 mRNA

NCBI chr 3:36,002,535...36,055,220
Ensembl chr 3:36,002,064...36,046,289

G

dynamin 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of DNM2 gene

NCBI chr 8:28,254,344...28,336,297
Ensembl chr 8:28,254,529...28,336,295

G

DNA methyltransferase 1

affects expression
multiple interactions
increases expression
affects activity

ISO
EXP

Folic Acid affects the expression of DNMT1 mRNA
[Methionine co-treated with Betaine co-treated with Choline co-treated with Folic Acid] inhibits the reaction [Carbon Tetrachloride results in increased expression of DNMT1 protein]
Folic Acid results in increased expression of DNMT1 mRNA; Folic Acid results in increased expression of DNMT1 protein
APP protein affects the reaction [Folic Acid affects the expression of DNMT1 mRNA]; Folic Acid inhibits the reaction [Arsenic results in decreased expression of DNMT1 mRNA]
[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency co-treated with sodium arsenite] results in decreased expression of DNMT1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of DNMT1 mRNA; Folic Acid affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of DNMT1 mRNA]; Folic Acid deficiency promotes the reaction [Streptozocin results in decreased expression of DNMT1 mRNA]; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of DNMT1 mRNA]; Folic Acid inhibits the reaction [Streptozocin results in decreased expression of DNMT1 mRNA]; trichostatin A inhibits the reaction [Folic Acid results in increased expression of DNMT1 mRNA]
Folic Acid affects the activity of DNMT1 protein

PMID:16855792 PMID:17311948 PMID:20978746 PMID:22206623 PMID:23219837 More...

NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:27,716,797...27,763,119

G

DNA methyltransferase 3 alpha

affects expression
increases expression
multiple interactions

ISO

Folic Acid affects the expression of DNMT3A mRNA
Folic Acid results in increased expression of DNMT3A mRNA; Folic Acid results in increased expression of DNMT3A protein
[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DNMT3A mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DNMT3A protein; [sodium arsenite co-treated with Folic Acid] results in decreased expression of DNMT3A mRNA; Decitabine inhibits the reaction [Folic Acid results in increased expression of DNMT3A mRNA]; Folic Acid affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of DNMT3A mRNA]; trichostatin A inhibits the reaction [Folic Acid results in increased expression of DNMT3A mRNA]

PMID:17311948 PMID:20548288 PMID:20938992 PMID:22959928 PMID:28475147 More...

NCBI chr 6:32,507,316...32,621,678
Ensembl chr 6:32,512,070...32,614,970

G

DNA methyltransferase 3 beta

affects expression
decreases expression
multiple interactions
increases expression

ISO

Folic Acid affects the expression of DNMT3B mRNA; Folic Acid affects the expression of DNMT3B protein
Folic Acid results in decreased expression of DNMT3B mRNA
APP protein affects the reaction [Folic Acid affects the expression of DNMT3B mRNA]; APP protein affects the reaction [Folic Acid affects the expression of DNMT3B protein]
Folic Acid results in increased expression of DNMT3B mRNA
[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DNMT3B protein; Decitabine inhibits the reaction [Folic Acid results in increased expression of DNMT3B mRNA]; Folic Acid affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of DNMT3B mRNA]; trichostatin A inhibits the reaction [Folic Acid results in increased expression of DNMT3B mRNA]

PMID:17311948 PMID:20548288 PMID:21867686 PMID:25629700 PMID:26492244 More...

NCBI chr 3:162,590,777...162,629,313
Ensembl chr 3:162,604,037...162,629,313

G

DNA methyltransferase 3 like

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DNMT3L mRNA

NCBI chr20:10,614,591...10,628,989
Ensembl chr20:10,614,591...10,629,168

G

aspartyl aminopeptidase

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DNPEP gene

NCBI chr 9:84,248,581...84,257,484
Ensembl chr 9:84,233,486...84,256,977

G

deoxynucleotidyltransferase, terminal, interacting protein 1

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of DNTTIP1 mRNA]

NCBI chr 3:173,901,070...173,924,742
Ensembl chr 3:173,900,945...173,925,098

G

deoxynucleotidyltransferase, terminal, interacting protein 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DNTTIP2 mRNA

NCBI chr 2:213,058,975...213,071,020
Ensembl chr 2:213,058,962...213,071,016

G

double C2 domain beta

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of DOC2B gene

NCBI chr10:61,126,295...61,151,533
Ensembl chr10:61,126,295...61,151,533

G

dedicator of cyto-kinesis 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DOCK1 mRNA

NCBI chr 1:198,897,021...199,413,636
Ensembl chr 1:198,897,045...199,413,627

G

dedicator of cytokinesis 10

multiple interactions
decreases expression

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of DOCK10 mRNA]
Folic Acid results in decreased expression of DOCK10 mRNA

PMID:22206623 PMID:25629700

NCBI chr 9:89,291,936...89,549,871
Ensembl chr 9:89,291,800...89,549,973

G

dedicator of cytokinesis 11

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DOCK11 mRNA

NCBI chr X:119,997,523...120,180,643
Ensembl chr X:119,997,552...120,180,634

G

dedicator of cytokinesis 4

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of DOCK4 mRNA
Folic Acid results in decreased expression of DOCK4 mRNA

PMID:20938992 PMID:25629700

NCBI chr 6:63,240,050...63,629,772
Ensembl chr 6:63,240,136...63,629,772

G

dedicator of cytokinesis 5

decreases expression

ISO

Folic Acid results in decreased expression of DOCK5 mRNA

NCBI chr15:46,155,124...46,334,127
Ensembl chr15:46,155,125...46,334,042

G

dedicator of cytokinesis 6

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of DOCK6 mRNA

NCBI chr 8:28,618,523...28,670,741
Ensembl chr 8:28,618,523...28,670,648

G

dedicator of cytokinesis 8

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of DOCK8 mRNA

NCBI chr 1:232,075,468...232,268,830
Ensembl chr 1:232,075,588...232,268,833

G

deoxyhypusine hydroxylase

multiple interactions
increases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DOHH mRNA
Folic Acid results in increased expression of DOHH mRNA

PMID:22206623 PMID:25629700

NCBI chr 7:8,972,202...8,977,025
Ensembl chr 7:8,972,202...8,977,025

G

docking protein 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DOK1 mRNA

NCBI chr 4:117,095,171...117,098,251
Ensembl chr 4:117,095,175...117,097,825

G

docking protein 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DOK2 mRNA

NCBI chr15:52,237,046...52,251,091
Ensembl chr15:52,236,900...52,251,074

G

docking protein 4

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DOK4 mRNA

NCBI chr19:10,152,511...10,163,182
Ensembl chr19:10,152,458...10,164,190

G

docking protein 5

increases expression

ISO

Folic Acid results in increased expression of DOK5 mRNA

NCBI chr 3:179,934,419...180,071,334
Ensembl chr 3:179,934,552...180,071,333

G

dolichol kinase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DOLK mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of DOLK gene

PMID:20938992 PMID:22206623

NCBI chr 3:33,955,642...33,957,680
Ensembl chr 3:33,954,308...33,958,365

G

dolichyldiphosphatase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DOLPP1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DOLPP1 gene

PMID:20938992 PMID:22206623

NCBI chr 3:34,063,825...34,072,133
Ensembl chr 3:34,063,825...34,072,132

G

DNA replication fork stabilization factor DONSON

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of DONSON mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DONSON mRNA

PMID:22206623 PMID:25629700

NCBI chr11:44,405,794...44,419,099
Ensembl chr11:44,405,804...44,418,791

G

dolichyl-phosphate N-acetylglucosaminephosphotransferase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DPAGT1 mRNA

NCBI chr 8:53,560,869...53,567,625
Ensembl chr 8:53,555,239...53,567,898

G

dipeptidase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DPEP1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DPEP1 mRNA

PMID:20938992 PMID:22206623

NCBI chr19:68,118,270...68,143,781
Ensembl chr19:68,118,453...68,143,775

G

double PHD fingers 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of DPF1 gene

NCBI chr 1:93,729,683...93,743,425
Ensembl chr 1:93,726,970...93,743,425

G

double PHD fingers 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DPF2 mRNA

NCBI chr 1:212,612,986...212,628,376
Ensembl chr 1:212,612,986...212,628,289

G

double PHD fingers 3

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DPF3 gene

NCBI chr 6:108,577,792...108,856,724
Ensembl chr 6:108,577,183...108,856,798

G

diphthamide biosynthesis 1

decreases expression

ISO

Folic Acid results in decreased expression of DPH1 mRNA

NCBI chr10:60,526,417...60,538,102
Ensembl chr10:60,527,680...60,535,816

G

diphthamide biosynthesis 2

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of DPH2 mRNA]

NCBI chr 5:136,713,868...136,716,828

G

diphthamide biosynthesis 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DPH3 mRNA

NCBI chr16:7,294,580...7,299,996
Ensembl chr16:7,294,580...7,299,996

G

dolichyl-phosphate mannosyltransferase subunit 2, regulatory

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DPM2 mRNA

NCBI chr 3:36,253,548...36,256,592

G

dolichyl-phosphate mannosyltransferase subunit 3, regulatory

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DPM3 mRNA

NCBI chr 2:176,974,290...176,974,805
Ensembl chr15:52,612,418...52,612,696

G

dipeptidyl peptidase like 10

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of DPP10 gene
Folic Acid results in decreased expression of DPP10 mRNA

PMID:20938992 PMID:25629700

NCBI chr13:37,145,531...38,821,987
Ensembl chr13:37,145,531...38,822,801

G

dipeptidylpeptidase 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DPP3 mRNA

NCBI chr 1:211,634,067...211,657,898
Ensembl chr 1:211,634,068...211,658,310

G

dipeptidyl peptidase like 6

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DPP6 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DPP6 gene

PMID:20938992 PMID:22206623

NCBI chr 4:8,323,220...9,242,694
Ensembl chr 4:8,324,843...9,242,209

G

dipeptidylpeptidase 7

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DPP7 mRNA

NCBI chr 3:28,563,240...28,567,492
Ensembl chr 3:28,563,240...28,567,492

G

dipeptidylpeptidase 8

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of DPP8 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DPP8 mRNA

PMID:22206623 PMID:25629700

NCBI chr 8:74,445,815...74,501,017
Ensembl chr 8:74,445,835...74,501,017

G

developmental pluripotency-associated 3

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DPPA3 mRNA

NCBI chr 4:157,523,426...157,526,810
Ensembl chr 5:93,143,318...93,144,472
Ensembl chr 4:93,143,318...93,144,472

G

dermatopontin

affects expression

ISO

Folic Acid affects the expression of DPT mRNA

NCBI chr13:79,656,341...79,684,759
Ensembl chr13:79,655,985...79,684,758

G

dpy-19 like C-mannosyltransferase 1

decreases expression

ISO

Folic Acid results in decreased expression of DPY19L1 mRNA

NCBI chr 8:31,209,025...31,297,485
Ensembl chr 8:31,209,025...31,297,518

G

dpy-30 histone methyltransferase complex regulatory subunit

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DPY30 mRNA

NCBI chr 6:26,872,812...26,893,580
Ensembl chr 6:26,872,732...26,894,930

G

dihydropyrimidine dehydrogenase

increases expression
multiple interactions

ISO

Folic Acid results in increased expression of DPYD mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DPYD mRNA

PMID:22206623 PMID:25629700

NCBI chr 2:209,293,902...210,159,777
Ensembl chr 2:209,293,929...210,159,778

G

dihydropyrimidinase-like 2

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of DPYSL2 mRNA]

NCBI chr15:45,181,041...45,287,065
Ensembl chr15:45,181,041...45,287,065

G

dihydropyrimidinase-like 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DPYSL3 mRNA

NCBI chr18:35,625,357...35,731,152
Ensembl chr18:35,625,357...35,731,152

G

dihydropyrimidinase-like 4

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DPYSL4 mRNA
Folic Acid results in increased expression of DPYSL4 mRNA

PMID:20938992 PMID:25629700

NCBI chr 1:203,312,646...203,328,523
Ensembl chr 1:203,311,694...203,328,523

G

down-regulator of transcription 1

decreases expression

ISO

Folic Acid results in decreased expression of DR1 mRNA

NCBI chr14:1,603,203...1,614,556
Ensembl chr14:1,603,204...1,614,556

G

DNA damage regulated autophagy modulator 2

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of DRAM2 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DRAM2 mRNA

PMID:22206623 PMID:25629700

NCBI chr 2:196,724,052...196,752,645
Ensembl chr 2:196,723,858...196,755,103

G

Dr1 associated protein 1

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of DRAP1 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DRAP1 mRNA

PMID:22206623 PMID:25629700

NCBI chr 1:212,161,107...212,163,833
Ensembl chr 1:212,161,125...212,163,762

G

dorsal inhibitory axon guidance protein

decreases expression

ISO

Folic Acid results in decreased expression of DRAXIN mRNA

NCBI chr 5:163,813,308...163,846,609
Ensembl chr 5:163,816,502...163,855,174

G

dopamine receptor D3

decreases expression

ISO

Folic Acid results in decreased expression of DRD3 mRNA

NCBI chr11:70,385,586...70,437,793
Ensembl chr11:70,385,586...70,446,760

G

dopamine receptor D4

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of DRD4 gene

NCBI chr 1:205,825,937...205,829,124
Ensembl chr 1:205,826,049...205,830,458

G

developmentally regulated GTP binding protein 1

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of DRG1 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DRG1 mRNA

PMID:22206623 PMID:25629700

NCBI chr14:82,328,320...82,344,416
Ensembl chr14:82,328,320...82,344,348

G

developmentally regulated GTP binding protein 2

multiple interactions
decreases expression

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of DRG2 mRNA]
Folic Acid results in decreased expression of DRG2 mRNA

PMID:22206623 PMID:25629700

NCBI chr10:45,755,072...45,769,493
Ensembl chr10:45,755,059...45,769,523

G

dorsal root ganglia homeobox

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of DRGX gene

NCBI chr16:7,861,024...7,891,607
Ensembl chr16:7,861,157...7,906,904

G

desmocollin 2

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of DSC2 mRNA
Folic Acid results in decreased expression of DSC2 mRNA

PMID:20938992 PMID:21867686

NCBI chr18:11,725,466...11,757,591
Ensembl chr18:11,725,466...11,757,466

G

DS cell adhesion molecule-like 1

increases expression

ISO

Folic Acid results in increased expression of DSCAML1 mRNA

NCBI chr 8:54,637,054...54,954,042
Ensembl chr 8:54,636,932...54,954,040

G

desmoglein 3

increases expression

ISO

Folic Acid results in increased expression of DSG3 mRNA

NCBI chr18:12,074,321...12,105,954
Ensembl chr18:12,074,321...12,111,766

G

desmoplakin

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DSP mRNA

NCBI chr17:26,829,153...26,877,419
Ensembl chr17:26,829,153...26,877,121

G

dentin sialophosphoprotein

decreases expression

ISO

Folic Acid results in decreased expression of DSPP mRNA

NCBI chr14:5,870,232...5,876,339
Ensembl chr14:5,870,232...5,876,339

G

dystonin

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DST mRNA; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of DST mRNA]
Folic Acid results in decreased expression of DST mRNA
[Ethanol co-treated with Folic Acid] results in increased expression of DST mRNA

PMID:20938992 PMID:21867686 PMID:22206623 PMID:23378141 PMID:25629700

NCBI chr 9:43,631,716...44,025,535
Ensembl chr 9:43,631,517...44,025,533

G

destrin, actin depolymerizing factor

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DSTN mRNA

NCBI chr 3:151,737,711...151,764,752
Ensembl chr 3:151,737,849...151,764,769

G

D-aminoacyl-tRNA deacylase 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DTD1 gene

NCBI chr 3:152,449,193...152,611,960
Ensembl chr 3:152,452,620...152,486,304

G

D-aminoacyl-tRNA deacylase 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DTD2 mRNA

NCBI chr 6:75,185,496...75,191,774
Ensembl chr 6:75,156,201...75,191,774

G

death domain containing 1

decreases expression

ISO

Folic Acid results in decreased expression of DTHD1 mRNA

NCBI chr14:50,773,694...50,877,217

G

denticleless E3 ubiquitin protein ligase homolog

decreases expression

ISO

Folic Acid results in decreased expression of DTL mRNA

NCBI chr13:105,646,908...105,685,921
Ensembl chr13:105,646,908...105,686,174

G

dystrobrevin, alpha

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DTNA mRNA
Folic Acid results in decreased expression of DTNA mRNA

PMID:20938992 PMID:25629700

NCBI chr18:14,862,801...15,218,993
Ensembl chr18:14,862,818...15,218,993

G

DTW domain containing 2

decreases expression

ISO

Folic Acid results in decreased expression of DTWD2 mRNA

PMID:21867686 PMID:25629700

NCBI chr18:45,003,242...45,088,595
Ensembl chr18:45,003,644...45,088,419

G

deltex E3 ubiquitin ligase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DTX1 mRNA

NCBI chr12:41,510,252...41,541,433
Ensembl chr12:41,510,264...41,541,430

G

deltex E3 ubiquitin ligase 3

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DTX3 mRNA

NCBI chr 7:64,898,693...64,904,636
Ensembl chr 7:64,898,866...64,903,752

G

deoxythymidylate kinase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DTYMK mRNA

NCBI chr 9:101,762,899...101,771,733
Ensembl chr 9:101,762,899...101,774,504

G

dual oxidase maturation factor 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DUOXA1 mRNA

NCBI chr 3:129,703,416...129,714,110
Ensembl chr 3:129,703,416...129,706,829

G

dihydrouridine synthase 1-like

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DUS1L gene

NCBI chr10:106,553,841...106,560,977
Ensembl chr10:106,553,238...106,561,285

G

dihydrouridine synthase 3-like

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DUS3L mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DUS3L gene

PMID:20938992 PMID:22206623

NCBI chr 9:1,680,619...1,685,784
Ensembl chr 9:1,675,819...1,686,367

G

dual specificity phosphatase 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of DUSP1 gene
Folic Acid results in decreased expression of DUSP1 mRNA

PMID:20938992 PMID:25629700

NCBI chr10:17,184,853...17,187,646
Ensembl chr10:17,184,823...17,187,644

G

dual specificity phosphatase 10

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DUSP10 mRNA
[Ethanol co-treated with Folic Acid] results in increased expression of DUSP10 mRNA

PMID:20938992 PMID:23378141

NCBI chr13:98,145,317...98,183,304
Ensembl chr13:98,145,893...98,183,304

G

dual specificity phosphatase 11

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DUSP11 mRNA
Folic Acid results in decreased expression of DUSP11 mRNA

PMID:20938992 PMID:25629700

NCBI chr 4:119,928,533...119,942,643
Ensembl chr 4:119,928,537...119,942,567

G

dual specificity phosphatase 12

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DUSP12 mRNA

NCBI chr13:85,654,914...85,666,431
Ensembl chr13:85,654,914...85,664,007

G

dual specificity phosphatase 14

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DUSP14 mRNA

NCBI chr10:69,433,949...69,463,863
Ensembl chr10:69,426,730...69,462,837

G

dual specificity phosphatase 18

decreases expression

ISO

Folic Acid results in decreased expression of DUSP18 mRNA

NCBI chr14:83,013,850...83,035,168
Ensembl chr14:83,011,014...83,056,929

G

dual specificity phosphatase 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DUSP2 mRNA

NCBI chr 3:135,009,636...135,011,821
Ensembl chr 3:135,009,590...135,011,809

G

dual specificity phosphatase 22

decreases expression

ISO

Folic Acid results in decreased expression of DUSP22 mRNA

NCBI chr17:33,989,637...34,040,021
Ensembl chr17:33,989,637...34,039,895

G

dual specificity phosphatase 26

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of DUSP26 gene

NCBI chr16:67,744,830...67,752,673
Ensembl chr16:67,744,842...67,752,101

G

dual specificity phosphatase 28

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DUSP28 mRNA
Folic Acid results in decreased expression of DUSP28 mRNA

PMID:22206623 PMID:25629700

NCBI chr 9:100,920,249...100,921,624
Ensembl chr 9:100,920,249...100,921,624

G

dual specificity phosphatase 4

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of DUSP4 gene
Folic Acid results in decreased expression of DUSP4 mRNA

PMID:20938992 PMID:25629700

NCBI chr16:64,079,893...64,101,396
Ensembl chr16:64,079,893...64,093,700

G

dual specificity phosphatase 6

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DUSP6 mRNA

NCBI chr 7:35,979,502...35,983,834
Ensembl chr 7:35,977,921...35,983,833

G

dual specificity phosphatase 7

increases expression
decreases expression

ISO

Folic Acid results in increased expression of DUSP7 mRNA
Folic Acid results in decreased expression of DUSP7 mRNA

PMID:21867686 PMID:25629700

NCBI chr 8:115,888,091...115,895,126
Ensembl chr 8:115,887,892...115,895,126

G

dual specificity phosphatase 8

decreases expression

ISO

Folic Acid results in decreased expression of DUSP8 mRNA

NCBI chr 1:206,596,912...206,613,728
Ensembl chr 1:206,598,942...206,612,441

G

dual specificity phosphatase 9

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of DUSP9; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DUSP9 gene; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DUSP9 mRNA

NCBI chr X:156,503,237...156,507,162
Ensembl chr X:156,503,190...156,507,161

G

deoxyuridine triphosphatase

decreases expression

ISO

Folic Acid results in decreased expression of DUT mRNA

NCBI chr 3:132,952,258...132,963,433
Ensembl chr 3:132,952,394...132,964,956

G

dishevelled segment polarity protein 1

multiple interactions

ISO

[Folic Acid co-treated with sodium arsenite] results in decreased methylation of DVL1 mRNA

NCBI chr 5:171,738,911...171,750,967
Ensembl chr 5:171,739,133...171,750,966

G

dishevelled segment polarity protein 2

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DVL2 gene
Folic Acid results in decreased expression of DVL2 mRNA

PMID:20938992 PMID:25629700

NCBI chr10:55,222,245...55,231,506
Ensembl chr10:55,222,056...55,231,506

G

dishevelled segment polarity protein 3

multiple interactions
decreases expression

ISO

[Folic Acid co-treated with sodium arsenite] results in increased methylation of DVL3 mRNA
Folic Acid results in decreased expression of DVL3 mRNA

PMID:22959928 PMID:25629700

NCBI chr11:93,869,834...93,887,013
Ensembl chr11:93,869,834...93,886,903

G

decapping exoribonuclease

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DXO mRNA

NCBI chr20:3,997,953...4,000,115
Ensembl chr20:3,997,955...4,000,037

G

dymeclin

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of DYM gene

NCBI chr18:70,879,835...71,176,006
Ensembl chr18:70,880,255...71,176,004

G

dynein cytoplasmic 1 heavy chain 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DYNC1H1 mRNA

NCBI chr 6:135,436,375...135,502,117
Ensembl chr 6:135,430,750...135,502,116

G

dynein cytoplasmic 1 intermediate chain 1

increases expression

ISO

Folic Acid results in increased expression of DYNC1I1 mRNA

NCBI chr 4:34,819,313...35,132,647
Ensembl chr 4:34,819,430...35,142,319

G

dynein cytoplasmic 1 intermediate chain 2

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of DYNC1I2 mRNA]

NCBI chr 3:76,441,621...76,492,782
Ensembl chr 3:76,424,469...76,492,782

G

dynein cytoplasmic 1 light intermediate chain 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DYNC1LI1 mRNA

NCBI chr 8:123,254,823...123,288,496
Ensembl chr 8:123,254,859...123,289,167

G

dynein, cytoplasmic 1 light intermediate chain 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DYNC1LI2 mRNA

NCBI chr19:538,207...561,110
Ensembl chr19:538,211...561,107

G

dynein 2 intermediate chain 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DYNC2I1 mRNA

NCBI chr 6:143,276,441...143,333,006
Ensembl chr 6:143,276,441...143,331,773

G

dynein 2 intermediate chain 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DYNC2I2 mRNA

NCBI chr 3:33,703,882...33,719,960
Ensembl chr 3:33,703,882...33,719,960

G

dynein cytoplasmic 2 light intermediate chain 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DYNC2LI1 mRNA

NCBI chr 6:15,745,350...15,778,166
Ensembl chr 6:15,745,350...15,778,166

G

dynein light chain LC8-type 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DYNLL1 mRNA

NCBI chr12:46,945,291...46,976,867
Ensembl chr12:46,973,050...46,976,861

G

dynein light chain LC8-type 2

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DYNLL2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of DYNLL2 mRNA
Folic Acid results in decreased expression of DYNLL2 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr10:73,264,260...73,283,042
Ensembl chr10:73,264,261...73,272,285

G

dynein light chain Tctex-type 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DYNLT1 mRNA

NCBI chr 1:49,292,093...49,299,051
Ensembl chr 1:49,282,243...49,298,951

G

dynein light chain Tctex-type 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DYNLT2A1 mRNA

NCBI chr 1:64,644,404...64,656,368
Ensembl chr 1:64,644,404...64,656,368

G

dynein light chain Tctex-type 2B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DYNLT2B mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DYNLT2B gene

PMID:20938992 PMID:22206623

NCBI chr11:81,864,195...81,872,555
Ensembl chr11:81,864,195...81,872,555

G

dynein light chain Tctex-type 3

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DYNLT3 mRNA
Folic Acid results in decreased expression of DYNLT3 mRNA

PMID:22206623 PMID:25629700

NCBI chr X:16,000,425...16,009,632
Ensembl chr X:16,000,395...16,009,627

G

dynein light chain Tctex-type 4

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of DYNLT4 gene

NCBI chr 5:135,842,044...135,843,807
Ensembl chr 5:135,830,930...135,844,474

G

dynein light chain Tctex-type family member 5

increases expression

ISO

Folic Acid results in increased expression of DYNLT5 mRNA

NCBI chr 5:122,964,568...122,987,304
Ensembl chr 5:122,964,845...122,987,304

G

dual specificity tyrosine phosphorylation regulated kinase 1A

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of DYRK1A mRNA
Folic Acid results in decreased expression of DYRK1A mRNA

PMID:20938992 PMID:25629700

NCBI chr11:47,360,824...47,479,033
Ensembl chr11:47,360,850...47,479,033

G

dual specificity tyrosine phosphorylation regulated kinase 2

decreases expression

ISO

Folic Acid results in decreased expression of DYRK2 mRNA

NCBI chr 7:56,235,276...56,265,741
Ensembl chr 7:56,235,276...56,265,942

G

dual specificity tyrosine phosphorylation regulated kinase 3

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DYRK3 gene
Folic Acid results in decreased expression of DYRK3 mRNA
[Folic Acid deficiency co-treated with Methotrexate] results in increased expression of DYRK3 mRNA

PMID:20938992 PMID:24657277 PMID:25629700

NCBI chr13:45,146,383...45,157,082
Ensembl chr13:45,146,384...45,157,249

G

dysferlin

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DYSF mRNA

NCBI chr 4:118,048,460...118,248,273
Ensembl chr 4:118,047,989...118,248,273

G

DAZ interacting zinc finger protein 1

decreases expression

ISO

Folic Acid results in decreased expression of DZIP1 mRNA

NCBI chr15:102,363,392...102,417,085
Ensembl chr15:102,363,392...102,417,085

G

DAZ interacting zinc finger protein 1-like

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DZIP1L mRNA

NCBI chr 8:109,067,466...109,108,390
Ensembl chr 8:109,067,775...109,108,393

G

E2F transcription factor 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of E2F1 gene

NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:163,524,739...163,535,563

G

E2F transcription factor 2

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of E2F2 mRNA]

NCBI chr 5:153,682,789...153,706,087
Ensembl chr 5:153,682,789...153,706,087

G

E2F transcription factor 4

decreases expression

ISO

Folic Acid results in decreased expression of E2F4 mRNA

NCBI chr19:50,084,335...50,091,731
Ensembl chr19:50,084,335...50,091,834

G

E2F transcription factor 6

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of E2F6 mRNA

NCBI chr 6:45,320,993...45,337,437
Ensembl chr 6:45,320,996...45,337,428

G

E2F transcription factor 7

increases expression

ISO

Folic Acid results in increased expression of E2F7 mRNA

NCBI chr 7:48,036,881...48,079,055
Ensembl chr 7:48,037,749...48,079,055

G

E2F transcription factor 8

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of E2F8 mRNA
[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of E2F8 mRNA

PMID:25629700 PMID:33549593

NCBI chr 1:107,701,985...107,720,538
Ensembl chr 1:107,701,985...107,720,009

G

E4F transcription factor 1

increases expression

ISO

Folic Acid results in increased expression of E4F1 mRNA

NCBI chr10:13,978,975...13,999,646
Ensembl chr10:13,978,990...13,990,506

G

ELL associated factor 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of EAF1 mRNA

NCBI chr16:6,704,727...6,719,476
Ensembl chr16:6,704,727...6,719,476

G

ELL associated factor 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of EAF2; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EAF2 gene; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EAF2 mRNA

NCBI chr11:77,465,585...77,509,993
Ensembl chr11:77,406,020...77,509,993

G

E2F-associated phosphoprotein

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of EAPP mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EAPP mRNA

PMID:22206623 PMID:25629700

NCBI chr 6:77,879,634...77,929,653
Ensembl chr 6:77,907,485...77,928,930

G

estrogen receptor binding site associated antigen 9

decreases expression

ISO

Folic Acid results in decreased expression of EBAG9 mRNA

NCBI chr 7:77,695,213...77,713,565
Ensembl chr 7:77,695,072...77,713,557

G

EBF transcription factor 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of EBF1 gene
Folic Acid results in decreased expression of EBF1 mRNA

PMID:20938992 PMID:25629700

NCBI chr10:29,597,221...29,990,571
Ensembl chr10:29,601,351...29,988,702

G

EBF transcription factor 2

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EBF2 gene
Folic Acid results in decreased expression of EBF2 mRNA

PMID:20938992 PMID:25629700

NCBI chr15:45,610,949...45,809,828
Ensembl chr15:45,610,949...45,809,822

G

Epstein-Barr virus induced 3

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of EBI3 gene

NCBI chr 9:861,441...874,731
Ensembl chr 9:870,792...874,973

G

EBNA1 binding protein 2

multiple interactions
increases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EBNA1BP2 mRNA
Folic Acid results in increased expression of EBNA1BP2 mRNA

PMID:22206623 PMID:25629700

NCBI chr 5:137,433,534...137,438,100
Ensembl chr 5:137,433,226...137,438,637

G

EBP, cholestenol delta-isomerase

multiple interactions
increases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EBP mRNA
Folic Acid results in increased expression of EBP mRNA

PMID:22206623 PMID:25629700

NCBI chr X:16,971,372...16,977,782
Ensembl chr X:16,971,405...16,977,781

G

EBP like

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EBPL gene

NCBI chr15:39,684,140...39,707,537
Ensembl chr15:39,684,140...39,707,537

G

ecdysoneless cell cycle regulator

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ECD mRNA]

NCBI chr15:4,016,411...4,047,899
Ensembl chr15:4,016,403...4,047,897

G

endothelin converting enzyme 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of and results in decreased expression of ECE1; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ECE1 gene

NCBI chr 5:155,361,031...155,462,723
Ensembl chr 5:155,360,639...155,462,719

G

endothelin-converting enzyme 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ECE2 gene

NCBI chr11:93,767,559...93,782,896
Ensembl chr11:93,767,559...93,793,292

G

endothelin converting enzyme-like 1

increases expression

ISO

Folic Acid results in increased expression of ECEL1 mRNA

NCBI chr 9:95,267,417...95,276,508
Ensembl chr 9:95,264,618...95,274,575

G

enoyl-CoA hydratase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ECH1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ECH1 gene

PMID:20938992 PMID:22206623

NCBI chr 1:93,241,076...93,248,314
Ensembl chr 1:93,241,734...93,248,440

G

ethylmalonyl-CoA decarboxylase 1

multiple interactions
increases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ECHDC1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ECHDC1 gene
Folic Acid results in increased expression of ECHDC1 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr 1:30,304,968...30,355,957
Ensembl chr 1:30,304,971...30,337,208

G

enoyl CoA hydratase domain containing 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ECHDC2 mRNA

NCBI chr 5:128,144,241...128,163,611
Ensembl chr 5:128,144,425...128,163,610

G

enoyl CoA hydratase domain containing 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ECHDC3 mRNA

NCBI chr17:76,980,112...77,002,934
Ensembl chr17:76,980,083...77,002,934

G

enoyl-CoA hydratase, short chain 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ECHS1 mRNA

NCBI chr 1:204,324,679...204,333,506
Ensembl chr 1:204,324,682...204,333,506

G

enoyl-CoA delta isomerase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ECI1 mRNA

NCBI chr10:13,961,250...13,974,595
Ensembl chr10:13,961,218...13,974,773

G

enoyl-CoA delta isomerase 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ECI2 mRNA

NCBI chr17:30,056,274...30,092,169
Ensembl chr17:30,076,524...30,092,161

G

extracellular matrix protein 1

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ECM1 mRNA]

NCBI chr 2:185,976,439...185,981,656
Ensembl chr 2:185,976,440...185,981,606

G

endothelial cell surface expressed chemotaxis and apoptosis regulator

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ECSCR mRNA]

NCBI chr18:27,583,791...27,593,184
Ensembl chr18:27,583,195...27,593,195

G

ECSIT signaling integrator

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ECSIT mRNA

NCBI chr 8:28,881,594...28,894,443
Ensembl chr 8:28,881,594...28,894,397

G

epithelial cell transforming 2

decreases expression

ISO

Folic Acid results in decreased expression of ECT2 mRNA

NCBI chr 2:111,904,522...111,966,786
Ensembl chr 2:111,904,522...111,966,626

G

EDAR associated via death domain

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of EDARADD mRNA

NCBI chr17:92,850,791...92,894,808
Ensembl chr17:92,831,613...92,894,361

G

ER degradation enhancing alpha-mannosidase like protein 1

decreases expression

ISO

Folic Acid results in decreased expression of EDEM1 mRNA

NCBI chr 4:143,350,989...143,385,693
Ensembl chr 4:143,353,624...143,388,060

G

EGF like repeats and discoidin domains 3

decreases expression

ISO

Folic Acid results in decreased expression of EDIL3 mRNA

NCBI chr 2:21,625,604...22,140,380
Ensembl chr 2:21,625,596...22,140,379

G

endothelin 1

decreases expression

ISO

Folic Acid results in decreased expression of EDN1 mRNA

NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687

G

endothelin 2

multiple interactions

ISO

Folic Acid affects the reaction [Cisplatin affects the expression of EDN2 mRNA]

NCBI chr 5:139,036,576...139,042,074
Ensembl chr 5:139,036,492...139,043,070

G

endothelin receptor type A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of EDNRA mRNA

NCBI chr19:47,137,360...47,207,961
Ensembl chr19:47,137,771...47,201,284

G

endothelin receptor type B

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EDNRB mRNA
Folic Acid results in decreased expression of EDNRB mRNA

PMID:20938992 PMID:25629700

NCBI chr15:87,055,490...87,086,765
Ensembl chr15:87,057,691...87,086,765

G

embryonic ectoderm development

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of EED mRNA]

NCBI chr 1:153,280,419...153,307,537
Ensembl chr 1:153,280,422...153,307,500

G

eukaryotic translation elongation factor 1 alpha 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EEF1A1 gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of EEF1A1 mRNA]
Folic Acid results in decreased expression of EEF1A1 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr 8:88,221,839...88,225,688
Ensembl chr 8:88,221,843...88,225,072

G

EEF1A lysine methyltransferase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EEF1AKMT1 mRNA

NCBI chr15:35,809,842...35,826,921
Ensembl chr15:35,809,842...35,827,129

G

EEF1A lysine methyltransferase 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EEF1AKMT2 mRNA

NCBI chr 1:197,009,919...197,071,033
Ensembl chr 1:197,046,930...197,071,013

G

EEF1A lysine methyltransferase 4

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EEF1AKMT4 mRNA

NCBI chr11:93,796,506...93,804,061
Ensembl chr11:93,796,506...93,804,061

G

eukaryotic translation elongation factor 1 beta 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of EEF1B2 mRNA

NCBI chr 9:72,074,091...72,076,591
Ensembl chr 9:72,073,802...72,076,589

G

eukaryotic translation elongation factor 1 delta

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of EEF1D mRNA

NCBI chr 7:109,462,645...109,478,021
Ensembl chr 7:109,462,646...109,489,531

G

eukaryotic translation elongation factor 1 epsilon 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EEF1E1 mRNA

NCBI chr17:26,354,247...26,364,953
Ensembl chr17:26,354,228...26,370,687

G

eukaryotic translation elongation factor 1 gamma

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EEF1G mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EEF1G mRNA

PMID:20938992 PMID:22206623

NCBI chr 1:215,289,815...215,300,421
Ensembl chr 1:215,277,860...215,301,479

G

eukaryotic elongation factor-2 kinase

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EEF2K gene

NCBI chr 1:184,824,420...184,888,048
Ensembl chr 1:184,824,420...184,888,048

G

eukaryotic elongation factor, selenocysteine-tRNA-specific

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of EEFSEC mRNA]

NCBI chr 4:122,276,907...122,473,049
Ensembl chr 4:122,263,535...122,473,049

G

EF-hand calcium binding domain 14

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EFCAB14 mRNA

NCBI chr 5:134,454,908...134,493,714
Ensembl chr 5:134,454,924...134,495,384

G

EF-hand calcium binding domain 3

decreases expression

ISO

Folic Acid results in decreased expression of EFCAB3 mRNA

NCBI chr10:90,084,495...90,577,145
Ensembl chr10:90,084,397...90,577,144

G

EGF containing fibulin extracellular matrix protein 1

decreases expression

ISO

Folic Acid results in decreased expression of EFEMP1 mRNA

NCBI chr14:106,811,769...106,890,961
Ensembl chr14:106,802,304...106,892,808

G

EGF containing fibulin extracellular matrix protein 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EFEMP2 mRNA

NCBI chr 1:212,211,057...212,218,739
Ensembl chr 1:212,210,972...212,218,739

G

EF-hand domain containing 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EFHC1 mRNA

NCBI chr 9:30,872,238...30,910,703
Ensembl chr 9:30,871,565...30,910,703

G

EF-hand domain containing 2

decreases expression

ISO

Folic Acid results in decreased expression of EFHC2 mRNA

NCBI chr X:7,943,603...8,144,073
Ensembl chr X:7,943,725...8,144,215

G

EF-hand domain family, member D1

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EFHD1 gene
Folic Acid results in increased expression of EFHD1 mRNA

PMID:20938992 PMID:21867686

NCBI chr 9:95,386,155...95,432,800
Ensembl chr 9:95,386,169...95,432,798

G

EF-hand domain family, member D2

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EFHD2 mRNA
Folic Acid results in decreased expression of EFHD2 mRNA

PMID:22206623 PMID:25629700

NCBI chr 5:159,443,959...159,459,993
Ensembl chr 5:159,443,960...159,460,369

G

ephrin A1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EFNA1 gene

NCBI chr 2:176,979,434...176,988,675
Ensembl chr 2:176,979,434...176,988,726

G

ephrin A2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of EFNA2 gene

NCBI chr 7:10,167,091...10,177,719
Ensembl chr 7:10,167,091...10,177,719

G

ephrin A3

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EFNA3 gene
Folic Acid results in decreased expression of EFNA3 mRNA

PMID:20938992 PMID:25629700

NCBI chr 2:177,026,928...177,035,838
Ensembl chr 2:177,026,933...177,044,843

G

ephrin A5

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EFNA5 gene

NCBI chr 9:109,763,786...110,042,396
Ensembl chr 9:109,767,252...110,042,348

G

ephrin B1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EFNB1 mRNA

NCBI chr X:68,297,529...68,310,335
Ensembl chr X:68,297,492...68,349,546

G

ephrin B2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of EFNB2 gene

NCBI chr16:87,485,215...87,529,224
Ensembl chr16:87,485,198...87,529,208

G

EFR3 homolog A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EFR3A mRNA

NCBI chr 7:99,441,764...99,522,454
Ensembl chr 7:99,441,767...99,522,454

G

EFR3 homolog B

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EFR3B gene

NCBI chr 6:32,664,593...32,740,417
Ensembl chr 6:32,666,945...32,740,417

G

embryonal Fyn-associated substrate

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of EFS mRNA

NCBI chr15:32,362,401...32,374,490
Ensembl chr15:32,361,843...32,371,743

G

elongation factor Tu GTP binding domain containing 2

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of EFTUD2 mRNA]

NCBI chr10:88,304,992...88,352,229
Ensembl chr10:88,304,992...88,346,299

G

EGF-like-domain, multiple 7

decreases expression

ISO

Folic Acid results in decreased expression of EGFL7 mRNA

NCBI chr 3:29,802,481...29,814,966
Ensembl chr 3:29,802,690...29,814,951

G

epidermal growth factor receptor

decreases expression
multiple interactions

ISO
EXP

Folic Acid results in decreased expression of EGFR mRNA
[Methionine co-treated with Betaine co-treated with Choline co-treated with Folic Acid] inhibits the reaction [Carbon Tetrachloride results in increased expression of EGFR mRNA]
[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of EGFR mRNA; EGFR protein affects the reaction [Folic Acid results in increased expression of HAVCR1 protein]; EGFR protein affects the reaction [Folic Acid results in increased expression of LCN2 protein]; EGFR protein affects the reaction [Folic Acid results in increased expression of PCNA protein]; EGFR protein affects the reaction [Folic Acid results in increased expression of VIM protein]; EGFR protein affects the reaction [Folic Acid results in increased phosphorylation of AKT1 protein]; EGFR protein affects the reaction [Folic Acid results in increased phosphorylation of EGFR protein]; Folic Acid results in increased expression of and results in increased phosphorylation of EGFR protein; Gefitinib inhibits the reaction [Folic Acid results in increased phosphorylation of EGFR protein]

PMID:23255615 PMID:25629700 PMID:33549593 PMID:39736447

NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358

G

egl-9 family hypoxia-inducible factor 2

increases expression

ISO

Folic Acid results in increased expression of EGLN2 mRNA

NCBI chr 1:91,579,205...91,586,985
Ensembl chr 1:91,579,206...91,587,385

G

egl-9 family hypoxia-inducible factor 3

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EGLN3 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of EGLN3 gene
Folic Acid results in decreased expression of EGLN3 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr 6:77,385,549...77,411,015
Ensembl chr 6:77,385,549...77,411,015

G

early growth response 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EGR1 mRNA; [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of EGR1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EGR1 gene
[Folic Acid co-treated with Arsenic] affects the expression of EGR1 mRNA; Folic Acid inhibits the reaction [Arsenic results in decreased methylation of EGR1 promoter]

PMID:20938992 PMID:22206623 PMID:33549593 PMID:35490796

NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843

G

early growth response 2

multiple interactions
affects expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EGR2 mRNA
Folic Acid deficiency affects the expression of EGR2 mRNA

PMID:20938992 PMID:32304770

NCBI chr20:21,050,149...21,055,201
Ensembl chr20:21,050,149...21,057,748

G

early growth response 3

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EGR3 gene

NCBI chr15:51,560,482...51,565,778
Ensembl chr15:51,560,344...51,565,712

G

EH domain binding protein 1

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of EHBP1 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EHBP1 mRNA

PMID:22206623 PMID:25629700

NCBI chr14:100,294,585...100,581,764
Ensembl chr14:100,294,585...100,546,579

G

EH domain binding protein 1-like 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EHBP1L1 gene

NCBI chr 1:212,423,444...212,444,357
Ensembl chr 1:212,423,447...212,443,598

G

EH-domain containing 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EHD1 mRNA

NCBI chr 1:213,009,113...213,031,488
Ensembl chr 1:213,008,049...213,031,485

G

EH-domain containing 2

decreases expression

ISO

Folic Acid results in decreased expression of EHD2 mRNA

NCBI chr 1:85,767,757...85,786,974
Ensembl chr 1:85,768,667...85,786,943

G

EH-domain containing 3

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of EHD3 mRNA

NCBI chr 6:27,392,709...27,417,445
Ensembl chr 6:27,392,709...27,417,445

G

EH-domain containing 4

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EHD4 mRNA

NCBI chr 3:127,511,973...127,575,856
Ensembl chr 3:127,511,954...127,576,072

G

ets homologous factor

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EHF mRNA

NCBI chr 3:110,094,770...110,134,991
Ensembl chr 3:110,096,756...110,134,928

G

EI24, autophagy associated transmembrane protein

decreases expression

ISO

Folic Acid results in decreased expression of EI24 mRNA

NCBI chr 8:44,683,138...44,699,502
Ensembl chr 8:44,683,144...44,695,214

G

EP300 interacting inhibitor of differentiation 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EID1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EID1 mRNA

PMID:20938992 PMID:22206623

NCBI chr 3:133,376,389...133,378,108
Ensembl chr 3:133,370,474...133,378,434

G

EP300 interacting inhibitor of differentiation 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EID2 mRNA

NCBI chr 1:92,665,837...92,667,162
Ensembl chr 1:92,665,481...92,675,307

G

EP300 interacting inhibitor of differentiation 2B

decreases expression

ISO

Folic Acid results in decreased expression of EID2B mRNA

NCBI chr 1:92,673,119...92,674,899

G

eukaryotic translation initiation factor 1

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of EIF1 mRNA]

NCBI chr10:85,747,064...85,749,447
Ensembl chr 5:25,895,968...25,896,654
Ensembl chr10:25,895,968...25,896,654

G

eukaryotic translation initiation factor 1A, X-linked

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EIF1AX mRNA

NCBI chr X:39,307,320...39,322,023
Ensembl chr X:39,307,137...39,322,021

G

eukaryotic translation initiation factor 2A

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EIF2A mRNA
Folic Acid results in decreased expression of EIF2A mRNA

PMID:22206623 PMID:25629700

NCBI chr 2:144,911,247...144,944,705
Ensembl chr 2:144,911,153...144,945,201

G

eukaryotic translation initiation factor 2 alpha kinase 3

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EIF2AK3 gene

NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:104,363,833...104,425,268

G

eukaryotic translation initiation factor 2 alpha kinase 4

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of EIF2AK4 mRNA

NCBI chr 3:125,810,207...125,895,574
Ensembl chr 3:125,810,060...125,895,574

G

eukaryotic translation initiation factor 2B subunit alpha

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EIF2B1 mRNA

NCBI chr12:37,686,149...37,694,830
Ensembl chr12:37,686,559...37,708,078

G

eukaryotic translation initiation factor 2B subunit beta

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EIF2B2 mRNA

NCBI chr 6:110,597,979...110,604,403
Ensembl chr 6:110,597,729...110,604,403

G

eukaryotic translation initiation factor 2B subunit delta

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of EIF2B4 gene

NCBI chr 6:30,903,148...30,908,803
Ensembl chr 6:30,903,219...30,908,800

G

eukaryotic translation initiation factor 2B subunit epsilon

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of EIF2B5 mRNA]

NCBI chr11:93,898,814...93,909,431
Ensembl chr11:93,898,814...93,908,800

G

eukaryotic translation initiation factor 2D

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of EIF2D mRNA]

NCBI chr13:45,168,161...45,189,362
Ensembl chr13:45,139,967...45,191,974

G

eukaryotic translation initiation factor 2 subunit alpha

decreases expression

ISO

Folic Acid results in decreased expression of EIF2S1 mRNA

NCBI chr 6:103,405,880...103,430,549
Ensembl chr 6:103,405,788...103,431,649

G

eukaryotic translation initiation factor 2 subunit gamma

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EIF2S3X mRNA

NCBI chr X:62,910,292...62,933,936
Ensembl chr X:62,910,293...62,934,489

G

eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked

increases expression

ISO

Folic Acid results in increased expression of EIF2S3Y mRNA

NCBI chr Y:944,653...964,303
Ensembl chr Y:944,618...964,778

G

eukaryotic translation initiation factor 3, subunit A

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of EIF3A mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EIF3A mRNA

PMID:22206623 PMID:25629700

NCBI chr 1:269,888,730...269,925,785
Ensembl chr 1:269,888,615...269,919,025

G

eukaryotic translation initiation factor 3, subunit B

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of EIF3B mRNA
Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of EIF3B mRNA]

PMID:22206623 PMID:25629700

NCBI chr12:19,310,308...19,334,768
Ensembl chr12:19,310,311...19,334,939

G

eukaryotic translation initiation factor 3, subunit C

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of EIF3C mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EIF3C mRNA

PMID:20938992 PMID:22206623

NCBI chr 1:190,565,183...190,583,067
Ensembl chr 1:190,565,184...190,583,067

G

eukaryotic translation initiation factor 3 subunit E

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EIF3E mRNA
Folic Acid results in decreased expression of EIF3E mRNA

PMID:22206623 PMID:25629700

NCBI chr 7:76,224,567...76,257,346
Ensembl chr 7:76,224,568...76,257,785

G

eukaryotic translation initiation factor 3, subunit F

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EIF3F mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EIF3F gene

PMID:20938992 PMID:22206623

NCBI chr 1:172,369,062...172,378,043
Ensembl chr 1:172,369,062...172,378,041

G

eukaryotic translation initiation factor 3, subunit G

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EIF3G mRNA

NCBI chr 8:27,705,914...27,709,946
Ensembl chr 8:27,705,915...27,709,987

G

eukaryotic translation initiation factor 3, subunit H

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EIF3H mRNA

NCBI chr 7:84,980,891...85,064,284
Ensembl chr 7:84,980,891...85,071,546

G

eukaryotic translation initiation factor 3, subunit I

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EIF3I mRNA

NCBI chr 5:147,219,457...147,226,910
Ensembl chr 5:147,219,366...147,241,232

G

eukaryotic translation initiation factor 3, subunit J

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EIF3J1 mRNA

NCBI chr 3:129,438,715...129,460,953
Ensembl chr 3:129,438,722...129,462,246

G

eukaryotic translation initiation factor 3, subunit L

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EIF3L mRNA

NCBI chr 7:112,522,222...112,544,063
Ensembl chr 7:112,507,831...112,544,062

G

eukaryotic translation initiation factor 3, subunit M

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EIF3M mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of EIF3M gene

PMID:20938992 PMID:22206623

NCBI chr 3:111,879,589...111,897,193
Ensembl chr 3:111,870,925...111,897,193

G

eukaryotic translation initiation factor 4A1

multiple interactions

EXP

[Folic Acid deficiency co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of EIF4A1 protein

NCBI chr10:54,883,093...54,888,602
Ensembl chr10:54,883,093...54,888,602

G

eukaryotic translation initiation factor 4A2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EIF4A2 mRNA

NCBI chr11:91,268,730...91,276,738
Ensembl chr11:91,268,731...91,275,323

G

eukaryotic translation initiation factor 4A3

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of EIF4A3 mRNA
Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of EIF4A3 mRNA]

PMID:22206623 PMID:25629700

NCBI chr10:105,047,567...105,057,561
Ensembl chr10:105,047,568...105,058,207

G

eukaryotic translation initiation factor 4B

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of EIF4B mRNA; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of EIF4B mRNA]

PMID:20938992 PMID:22206623

NCBI chr 7:135,085,259...135,107,054
Ensembl chr 7:135,085,066...135,107,064

G

eukaryotic translation initiation factor 4E

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EIF4E mRNA

NCBI chr 2:229,736,309...229,772,628
Ensembl chr 2:229,739,897...229,774,105

G

eukaryotic translation initiation factor 4E family member 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of and results in decreased expression of EIF4E2; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of EIF4E2 gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of EIF4E2 mRNA]

PMID:20938992 PMID:22206623

NCBI chr 9:95,333,439...95,362,366
Ensembl chr 9:95,333,989...95,362,362

G

eukaryotic translation initiation factor 4E family member 3

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of EIF4E3 mRNA]

NCBI chr 4:133,709,802...133,858,398
Ensembl chr 4:133,625,768...133,885,647

G

eukaryotic translation initiation factor 4E binding protein 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of EIF4EBP1 mRNA

NCBI chr16:71,495,457...71,508,845
Ensembl chr16:71,487,930...71,508,874

G

eukaryotic translation initiation factor 4E binding protein 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EIF4EBP2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of EIF4EBP2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EIF4EBP2 gene

PMID:20938992 PMID:22206623

NCBI chr20:29,922,260...29,942,922
Ensembl chr20:29,922,260...29,942,922

G

eukaryotic translation initiation factor 4E binding protein 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EIF4EBP3 mRNA

NCBI chr18:28,540,324...28,542,070
Ensembl chr18:28,540,058...28,542,061

G

eukaryotic translation initiation factor 4 gamma 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of EIF4G1 mRNA

NCBI chr11:93,726,322...93,746,387
Ensembl chr11:93,726,322...93,746,367

G

eukaryotic translation initiation factor 4, gamma 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EIF4G2 mRNA

NCBI chr 1:174,616,102...174,628,252
Ensembl chr 1:174,616,103...174,628,252

G

eukaryotic translation initiation factor 4 gamma, 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EIF4G3 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of EIF4G3 gene

PMID:20938992 PMID:22206623

NCBI chr 5:155,481,378...155,702,194
Ensembl chr 5:155,481,378...155,702,194

G

eukaryotic translation initiation factor 4H

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EIF4H mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EIF4H gene

PMID:20938992 PMID:22206623

NCBI chr12:27,719,527...27,736,350
Ensembl chr12:27,719,321...27,736,346

G

eukaryotic translation initiation factor 5

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EIF5 mRNA

NCBI chr 6:136,410,333...136,418,827
Ensembl chr 6:136,407,440...136,418,821

G

eukaryotic translation initiation factor 5A

decreases expression

ISO

Folic Acid results in decreased expression of EIF5A mRNA

NCBI chr10:55,138,821...55,143,272
Ensembl chr10:55,138,823...55,143,330

G

eukaryotic translation initiation factor 5A2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of EIF5A2 mRNA

NCBI chr 2:113,656,748...113,674,598
Ensembl chr 2:113,657,797...113,674,594

G

elastase, neutrophil expressed

decreases expression

ISO

Folic Acid results in decreased expression of ELANE mRNA

NCBI chr 7:10,467,877...10,469,725
Ensembl chr 7:10,467,877...10,469,725

G

endosome-lysosome associated apoptosis and autophagy regulator 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ELAPOR1 mRNA

NCBI chr 2:198,777,323...198,856,497
Ensembl chr 2:198,777,323...198,856,497

G

ELAV like RNA binding protein 1

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of ELAVL1 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ELAVL1 mRNA

PMID:22206623 PMID:25629700

NCBI chr12:7,441,699...7,482,625
Ensembl chr12:7,441,699...7,482,631

G

ELAV like RNA binding protein 2

decreases expression

ISO

Folic Acid results in decreased expression of ELAVL2 mRNA

NCBI chr 5:111,076,705...111,202,341
Ensembl chr 5:111,076,705...111,224,918

G

ELAV like RNA binding protein 3

decreases expression

ISO

Folic Acid results in decreased expression of ELAVL3 mRNA

NCBI chr 8:28,823,120...28,859,395
Ensembl chr 8:28,825,707...28,859,659

G

ELAV like RNA binding protein 4

decreases expression

ISO

Folic Acid results in decreased expression of ELAVL4 mRNA

NCBI chr 5:130,285,418...130,429,106
Ensembl chr 5:130,285,418...130,429,096

G

E74 like ETS transcription factor 2

decreases expression

ISO

Folic Acid results in decreased expression of ELF2 mRNA

NCBI chr 2:137,445,787...137,536,512
Ensembl chr 2:137,445,788...137,470,355

G

E74 like ETS transcription factor 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ELF3 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ELF3 mRNA
[Ethanol co-treated with Folic Acid] results in increased expression of ELF3 mRNA

PMID:20938992 PMID:22206623 PMID:23378141

NCBI chr13:49,242,265...49,247,102
Ensembl chr13:49,242,267...49,247,380

G

E74 like ETS transcription factor 4

increases expression

ISO

Folic Acid results in increased expression of ELF4 mRNA

NCBI chr X:132,465,290...132,508,175
Ensembl chr X:132,468,539...132,478,689

G

E74 like ETS transcription factor 5

decreases expression

ISO

Folic Acid results in decreased expression of ELF5 mRNA

NCBI chr 3:110,264,460...110,291,926
Ensembl chr 3:110,252,797...110,291,926

G

extracellular leucine-rich repeat and fibronectin type III domain containing 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ELFN1 gene

NCBI chr12:19,773,911...19,839,375
Ensembl chr12:19,772,908...19,841,961

G

ETS transcription factor ELK3

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ELK3 mRNA]

NCBI chr 7:29,655,676...29,718,163
Ensembl chr 7:29,655,693...29,691,661

G

ETS transcription factor ELK4

decreases expression

ISO

Folic Acid results in decreased expression of ELK4 mRNA

PMID:21867686 PMID:25629700

NCBI chr13:46,004,145...46,027,206
Ensembl chr13:46,004,182...46,027,199

G

elongation factor for RNA polymerase II 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ELL2 gene

NCBI chr 2:6,910,446...6,990,654
Ensembl chr 2:6,921,771...7,016,199

G

engulfment and cell motility 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ELMO3 mRNA

NCBI chr19:50,091,883...50,096,324
Ensembl chr19:50,091,924...50,096,338

G

elastin

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ELN mRNA

NCBI chr12:27,604,983...27,648,413
Ensembl chr12:27,604,680...27,648,413

G

elongin B

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ELOB mRNA
Folic Acid results in decreased expression of ELOB mRNA

PMID:22206623 PMID:25629700

NCBI chr10:13,353,413...13,358,484
Ensembl chr10:13,353,417...13,358,563

G

elongation factor 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ELOF1 mRNA

NCBI chr 8:28,921,338...28,926,612
Ensembl chr 8:28,921,339...28,926,228

G

ELOVL fatty acid elongase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ELOVL1 mRNA

NCBI chr 5:137,246,781...137,251,351
Ensembl chr 5:137,246,849...137,251,352

G

ELOVL fatty acid elongase 4

decreases expression

ISO

Folic Acid results in decreased expression of ELOVL4 mRNA

NCBI chr 8:93,582,930...93,609,479
Ensembl chr 8:93,582,930...93,609,678

G

ELOVL fatty acid elongase 5

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ELOVL5 mRNA

NCBI chr 8:87,671,164...87,737,618
Ensembl chr 8:87,671,159...87,737,616

G

ELOVL fatty acid elongase 6

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ELOVL6 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ELOVL6 mRNA

PMID:20938992 PMID:22206623

NCBI chr 2:220,738,095...220,845,528
Ensembl chr 2:220,738,064...220,845,549

G

ELOVL fatty acid elongase 7

multiple interactions
decreases expression

ISO

[Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of ELOVL7 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ELOVL7 mRNA
Folic Acid results in decreased expression of ELOVL7 mRNA

PMID:20938992 PMID:21867686 PMID:25629700 PMID:29127188

NCBI chr 2:41,522,695...41,592,021
Ensembl chr 2:41,522,738...41,592,020

G

elongator acetyltransferase complex subunit 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ELP1 mRNA

NCBI chr 5:76,248,545...76,300,985
Ensembl chr 5:76,248,550...76,300,985

G

elongator acetyltransferase complex subunit 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ELP2 mRNA

NCBI chr18:16,160,686...16,196,307
Ensembl chr18:16,160,671...16,196,414

G

elongator acetyltransferase complex subunit 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ELP3 mRNA

NCBI chr15:43,930,234...43,992,065
Ensembl chr15:43,930,234...43,992,214

G

elongator acetyltransferase complex subunit 4

decreases expression

ISO

Folic Acid results in decreased expression of ELP4 mRNA

NCBI chr 3:112,617,020...112,839,963
Ensembl chr 3:112,617,035...112,839,963

G

elongator acetyltransferase complex subunit 5

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ELP5 mRNA

NCBI chr10:55,191,223...55,202,949
Ensembl chr10:55,191,227...55,203,617

G

embigin

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EMB mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of EMB gene

NCBI chr 2:50,803,468...50,858,001
Ensembl chr 2:50,801,973...50,862,920

G

ER membrane protein complex subunit 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EMC1 mRNA

NCBI chr 5:156,891,773...156,917,092
Ensembl chr 5:156,891,773...156,917,092

G

ER membrane protein complex subunit 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EMC2 mRNA

NCBI chr 7:76,471,899...76,508,866
Ensembl chr 7:76,471,899...76,510,178

G

ER membrane protein complex subunit 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EMC3 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of EMC3 gene

PMID:20938992 PMID:22206623

NCBI chr 4:148,218,686...148,234,595
Ensembl chr 4:148,217,395...148,234,595

G

ER membrane protein complex subunit 4

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EMC4 mRNA

NCBI chr 3:119,624,100...119,633,170
Ensembl chr 3:119,624,100...119,629,118

G

ER membrane protein complex subunit 6

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EMC6 mRNA

NCBI chr10:58,292,584...58,293,850
Ensembl chr10:58,292,470...58,298,885

G

ER membrane protein complex subunit 7

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EMC7 mRNA

NCBI chr 3:119,714,617...119,728,748
Ensembl chr 3:119,718,357...119,730,486

G

ER membrane protein complex subunit 8

decreases expression

ISO

Folic Acid results in decreased expression of EMC8 mRNA

NCBI chr19:65,620,365...65,630,328
Ensembl chr19:65,620,375...65,630,235

G

ER membrane protein complex subunit 9

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EMC9 mRNA

NCBI chr15:33,041,840...33,046,056
Ensembl chr15:33,041,842...33,046,102

G

emerin

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EMD mRNA

NCBI chr X:157,190,438...157,193,479
Ensembl chr X:157,189,819...157,197,095

G

EMG1 N1-specific pseudouridine methyltransferase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EMG1 mRNA

NCBI chr 4:159,195,545...159,203,826
Ensembl chr 4:159,195,564...159,203,826

G

EMI domain containing 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EMID1 mRNA

NCBI chr14:84,214,530...84,257,628
Ensembl chr14:84,214,530...84,257,579

G

elastin microfibril interfacer 2

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EMILIN2 mRNA
Folic Acid results in decreased expression of EMILIN2 mRNA

PMID:20938992 PMID:25629700

NCBI chr 9:118,607,312...118,667,087
Ensembl chr 9:118,606,891...118,666,957

G

elastin microfibril interfacer 3

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of EMILIN3 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of EMILIN3 gene

NCBI chr 3:169,978,488...169,984,718
Ensembl chr 3:169,978,672...169,984,488

G

EMAP like 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EML1 mRNA

NCBI chr 6:133,048,271...133,221,642
Ensembl chr 6:133,048,427...133,221,642

G

EMAP like 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EML2 mRNA

NCBI chr 1:87,955,924...87,987,366
Ensembl chr 1:87,955,606...87,987,366

G

EMAP like 4

decreases expression

ISO

Folic Acid results in decreased expression of EML4 mRNA

NCBI chr 6:16,972,054...17,087,365
Ensembl chr 6:16,972,075...17,087,439

G

EMAP like 6

decreases expression

ISO

Folic Acid results in decreased expression of EML6 mRNA

NCBI chr14:107,651,893...108,006,792
Ensembl chr14:107,699,400...108,005,409

G

epithelial membrane protein 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EMP1 mRNA

NCBI chr 4:169,931,537...169,964,366
Ensembl chr 4:169,931,440...169,964,365

G

epithelial membrane protein 2

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EMP2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EMP2 mRNA
Folic Acid results in decreased expression of EMP2 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr10:5,866,869...5,901,533
Ensembl chr10:5,866,922...5,901,532

G

epithelial membrane protein 3

decreases expression

ISO

Folic Acid results in decreased expression of EMP3 mRNA

NCBI chr 1:105,525,086...105,528,370
Ensembl chr 1:105,525,088...105,528,265

G

empty spiracles homeobox 2

multiple interactions

ISO

Folic Acid inhibits the reaction [ochratoxin A results in decreased expression of EMX2 mRNA]

NCBI chr 1:268,612,663...268,619,671
Ensembl chr 1:268,612,663...268,619,671

G

Emx2 opposite strand/antisense RNA

decreases expression

ISO

Folic Acid results in decreased expression of EMX2OS mRNA

NCBI chr 1:268,555,719...268,612,889

G

ENAH, actin regulator

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ENAH mRNA

NCBI chr13:96,149,437...96,269,841
Ensembl chr13:96,149,437...96,269,796

G

ectodermal-neural cortex 1

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ENC1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ENC1 mRNA
Folic Acid results in decreased expression of ENC1 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr 2:30,285,274...30,297,194
Ensembl chr 2:30,283,736...30,315,721

G

endonuclease domain containing 1

multiple interactions
increases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ENDOD1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ENDOD1 gene
Folic Acid results in increased expression of ENDOD1 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr 8:19,490,615...19,520,007
Ensembl chr 8:19,490,615...19,520,007

G

endonuclease G

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ENDOG mRNA

NCBI chr 3:33,846,935...33,849,531
Ensembl chr 3:33,846,885...33,849,573

G

endonuclease V

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ENDOV mRNA

NCBI chr10:105,258,540...105,276,209
Ensembl chr10:105,258,593...105,276,209

G

endoglin

decreases expression

ISO

Folic Acid results in decreased expression of ENG mRNA

NCBI chr 3:36,332,190...36,370,324
Ensembl chr 3:36,326,202...36,370,933

G

enkurin domain containing 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ENKD1 mRNA

NCBI chr19:50,501,963...50,506,447
Ensembl chr19:50,501,963...50,506,942

G

enolase 1

multiple interactions

EXP
ISO

[Folic Acid deficiency co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of ENO1 protein
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ENO1 mRNA

PMID:19566968 PMID:22206623

NCBI chr 5:166,002,867...166,014,252
Ensembl chr 3:77,946,261...77,986,003
Ensembl chr 5:77,946,261...77,986,003

G

enolase 2

increases expression

ISO

Folic Acid results in increased expression of ENO2 mRNA

NCBI chr 4:159,258,371...159,267,220
Ensembl chr 4:159,258,371...159,267,220

G

enolase-phosphatase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ENOPH1 mRNA

NCBI chr14:9,835,626...9,862,051
Ensembl chr14:9,835,627...9,873,668

G

ecto-NOX disulfide-thiol exchanger 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ENOX1 gene

NCBI chr15:58,924,519...59,488,919
Ensembl chr15:59,215,018...59,488,918

G

ecto-NOX disulfide-thiol exchanger 2

decreases expression

ISO

Folic Acid results in decreased expression of ENOX2 mRNA

NCBI chr X:133,148,813...133,470,914
Ensembl chr X:133,148,813...133,470,891

G

ectonucleotide pyrophosphatase/phosphodiesterase 1

increases expression
decreases expression

ISO

Folic Acid results in increased expression of ENPP1 mRNA
Folic Acid results in decreased expression of ENPP1 mRNA

PMID:21867686 PMID:25629700

NCBI chr 1:22,518,051...22,583,044
Ensembl chr 1:22,518,069...22,583,044

G

ectonucleotide pyrophosphatase/phosphodiesterase 3

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ENPP3 mRNA

NCBI chr 1:22,382,717...22,454,324
Ensembl chr 1:22,382,964...22,454,314

G

ectonucleotide pyrophosphatase/phosphodiesterase 4

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of ENPP4 mRNA]

NCBI chr 9:24,386,351...24,396,248
Ensembl chr 9:24,360,272...24,396,152

G

ectonucleotide pyrophosphatase/phosphodiesterase family member 5

decreases expression

ISO

Folic Acid results in decreased expression of ENPP5 mRNA

NCBI chr 9:24,407,574...24,415,029
Ensembl chr 9:24,408,218...24,414,867

G

endosulfine alpha

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ENSA mRNA

NCBI chr 2:185,874,500...185,881,838
Ensembl chr 2:185,874,500...185,881,838

G

ectonucleoside triphosphate diphosphohydrolase 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ENTPD2 mRNA

NCBI chr 3:28,611,722...28,617,237
Ensembl chr 3:28,611,772...28,618,184

G

ectonucleoside triphosphate diphosphohydrolase 4

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ENTPD4 mRNA

NCBI chr15:51,040,665...51,068,450
Ensembl chr15:51,040,673...51,068,441

G

ectonucleoside triphosphate diphosphohydrolase 5

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ENTPD5 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ENTPD5 gene

PMID:20938992 PMID:22206623

NCBI chr 6:109,750,210...109,786,376
Ensembl chr 6:109,753,204...109,786,495

G

ectonucleoside triphosphate diphosphohydrolase 7

multiple interactions

ISO

[Folic Acid deficiency co-treated with Methotrexate] results in increased expression of ENTPD7 mRNA

NCBI chr 1:252,508,594...252,550,269
Ensembl chr 1:252,508,594...252,550,269

G

endosomal transmembrane epsin interactor 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ENTREP3 mRNA

NCBI chr 2:176,886,903...176,893,047
Ensembl chr 2:176,887,135...176,893,047

G

ENY2, transcription and export complex 2 subunit

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ENY2 mRNA

NCBI chr 7:77,465,885...77,489,637
Ensembl chr 7:77,466,119...77,491,057

G

EGF domain specific O-linked N-acetylglucosamine transferase

decreases expression

ISO

Folic Acid results in decreased expression of EOGT mRNA

NCBI chr 4:131,275,587...131,313,243
Ensembl chr 4:131,276,573...131,311,926

G

E1A binding protein p300

decreases expression

ISO

Folic Acid results in decreased expression of EP300 mRNA

NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574

G

endothelial PAS domain protein 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of EPAS1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EPAS1 gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of EPAS1 mRNA]

PMID:20938992 PMID:22206623

NCBI chr 6:13,543,252...13,626,147
Ensembl chr 6:13,544,389...13,624,729

G

erythrocyte membrane protein band 4.1-like 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EPB41L1 mRNA

NCBI chr 3:165,389,295...165,512,821
Ensembl chr 3:165,389,293...165,510,498

G

erythrocyte membrane protein band 4.1-like 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of EPB41L3 mRNA

NCBI chr 9:116,502,864...116,707,274
Ensembl chr 9:116,462,807...116,707,274

G

erythrocyte membrane protein band 4.1 like 4A

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of EPB41L4A; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EPB41L4A mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of EPB41L4A gene
Folic Acid results in decreased expression of EPB41L4A mRNA

PMID:20938992 PMID:25629700

NCBI chr18:25,680,169...25,890,998
Ensembl chr18:25,680,171...25,888,498

G

erythrocyte membrane protein band 4.1 like 4B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EPB41L4B mRNA

NCBI chr 5:76,486,886...76,647,752
Ensembl chr 5:76,486,902...76,647,752

G

enhancer of polycomb homolog 1

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EPC1 mRNA
Folic Acid results in decreased expression of EPC1 mRNA

PMID:22206623 PMID:25629700

NCBI chr17:59,198,513...59,289,535
Ensembl chr17:59,197,677...59,289,519

G

enhancer of polycomb homolog 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EPC2 gene

NCBI chr 3:54,276,187...54,376,373
Ensembl chr 3:54,276,239...54,376,916

G

epithelial cell adhesion molecule

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EPCAM mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EPCAM mRNA

PMID:20938992 PMID:22206623

NCBI chr 6:12,633,715...12,649,678
Ensembl chr 6:12,631,611...12,649,702

G

ependymin related 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EPDR1 mRNA

NCBI chr17:50,029,591...50,054,254
Ensembl chr17:50,029,256...50,054,250

G

epithelial mitogen

increases expression

ISO

Folic Acid results in increased expression of EPGN mRNA

NCBI chr14:17,360,968...17,369,000
Ensembl chr14:17,360,968...17,369,000

G

Eph receptor A2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EPHA2 mRNA

NCBI chr 5:158,888,629...158,917,100
Ensembl chr 5:158,888,629...158,917,234

G

Eph receptor A3

decreases expression

ISO

Folic Acid results in decreased expression of EPHA3 mRNA

NCBI chr11:14,585,041...14,920,721
Ensembl chr11:14,586,727...14,920,425

G

Eph receptor A4

decreases expression

ISO

Folic Acid results in decreased expression of EPHA4 mRNA

NCBI chr 9:86,263,982...86,406,744
Ensembl chr 9:86,263,982...86,406,755

G

EPH receptor A5

decreases expression

ISO

Folic Acid results in decreased expression of EPHA5 mRNA

NCBI chr14:24,007,400...24,374,854
Ensembl chr14:24,008,122...24,374,848

G

Eph receptor A7

multiple interactions
decreases expression

ISO

[Doxorubicin co-treated with Folic Acid] results in increased expression of EPHA7 mRNA
Folic Acid results in decreased expression of EPHA7 mRNA

PMID:25629700 PMID:28608983

NCBI chr 5:47,771,776...47,925,189
Ensembl chr 5:47,771,865...47,925,058

G

Eph receptor A8

increases expression

ISO

Folic Acid results in increased expression of EPHA8 mRNA

NCBI chr 5:154,449,566...154,476,966
Ensembl chr 5:154,449,566...154,476,966

G

Eph receptor B1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of EPHB1 gene

NCBI chr 8:111,386,432...111,823,759
Ensembl chr 8:111,386,432...111,823,759

G

Eph receptor B2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of EPHB2 gene

NCBI chr 5:154,179,065...154,360,459
Ensembl chr 5:154,179,065...154,360,615

G

Eph receptor B3

increases expression
multiple interactions

ISO

Folic Acid results in increased expression of EPHB3 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of EPHB3 mRNA

PMID:22206623 PMID:25629700

NCBI chr11:93,345,098...93,363,775
Ensembl chr11:93,345,098...93,363,775

G

Eph receptor B6

affects expression

ISO

Folic Acid affects the expression of EPHB6 mRNA

NCBI chr 4:71,458,632...71,473,889
Ensembl chr 4:71,458,971...71,476,659

G

epoxide hydrolase 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EPHX2 mRNA

NCBI chr15:44,465,447...44,503,157
Ensembl chr15:44,465,448...44,503,160

G

epoxide hydrolase 3

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EPHX3 gene

NCBI chr 7:11,857,367...11,862,674
Ensembl chr 7:11,857,367...11,862,674

G

EPM2A interacting protein 1

decreases expression

ISO

Folic Acid results in decreased expression of EPM2AIP1 mRNA

NCBI chr 8:120,112,265...120,119,613
Ensembl chr 8:120,112,084...120,121,458

G

Epsin 1

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of EPN1 mRNA]

NCBI chr 1:77,771,335...77,789,411
Ensembl chr 1:77,771,335...77,789,411

G

epsin 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EPN2 gene

NCBI chr10:46,697,238...46,759,128
Ensembl chr10:46,697,238...46,759,092

G

epiplakin 1

decreases expression

ISO

Folic Acid results in decreased expression of EPPK1 mRNA

NCBI chr 7:109,697,607...109,718,468
Ensembl chr 7:109,697,607...109,718,468

G

glutamyl-prolyl-tRNA synthetase 1

decreases expression

ISO

Folic Acid results in decreased expression of EPRS1 mRNA

NCBI chr13:99,431,955...99,503,510
Ensembl chr13:99,433,130...99,503,509

G

epidermal growth factor receptor pathway substrate 15

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EPS15 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EPS15 mRNA

PMID:20938992 PMID:22206623

NCBI chr 5:129,274,487...129,374,856
Ensembl chr 5:129,274,502...129,374,856

G

epidermal growth factor receptor pathway substrate 15-like 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EPS15L1 mRNA

NCBI chr16:17,460,330...17,573,824
Ensembl chr16:17,460,465...17,535,703

G

EGFR pathway substrate 8, signaling adaptor

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EPS8 mRNA
Folic Acid results in decreased expression of EPS8 mRNA

PMID:22206623 PMID:25629700

NCBI chr 4:172,119,497...172,291,670
Ensembl chr 4:172,119,497...172,218,160

G

EPS8 signaling adaptor L3

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EPS8L3 mRNA

NCBI chr 2:198,202,862...198,216,255
Ensembl chr 2:198,200,486...198,216,255

G

epithelial stromal interaction 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EPSTI1 mRNA

NCBI chr15:59,692,712...59,791,376
Ensembl chr15:59,693,142...59,791,380

G

Era-like 12S mitochondrial rRNA chaperone 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ERAL1 mRNA

NCBI chr10:63,459,774...63,466,829
Ensembl chr10:63,459,774...63,468,225

G

erb-b2 receptor tyrosine kinase 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ERBB2 mRNA

NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,907,460...83,931,481

G

erb-b2 receptor tyrosine kinase 3

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ERBB3 mRNA

NCBI chr 7:1,579,079...1,600,379
Ensembl chr 7:1,579,816...1,601,120

G

ELKS/RAB6-interacting/CAST family member 1

decreases expression

ISO

Folic Acid results in decreased expression of ERC1 mRNA

NCBI chr 4:154,435,936...154,727,987
Ensembl chr 4:154,435,944...154,727,987

G

ELKS/RAB6-interacting/CAST family member 2

decreases expression

ISO

Folic Acid results in decreased expression of ERC2 mRNA

NCBI chr16:2,819,399...3,680,258
Ensembl chr16:2,819,512...3,680,258

G

ERCC excision repair 1, endonuclease non-catalytic subunit

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ERCC1 gene; Folic Acid inhibits the reaction [Benzo(a)pyrene results in decreased expression of ERCC1 mRNA]
[Folic Acid co-treated with Benzo(a)pyrene] results in increased expression of ERCC1 mRNA; Folic Acid inhibits the reaction [Benzo(a)pyrene results in decreased expression of ERCC1 protein]

PMID:20938992 PMID:30020114

NCBI chr 1:88,099,308...88,135,966
Ensembl chr 1:88,118,891...88,139,120

G

ERCC excision repair 3, TFIIH core complex helicase subunit

multiple interactions
decreases expression

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ERCC3 mRNA]
Folic Acid results in decreased expression of ERCC3 mRNA

PMID:22206623 PMID:25629700

NCBI chr18:24,157,831...24,188,543
Ensembl chr18:24,148,084...24,190,898

G

ERCC excision repair 4, endonuclease catalytic subunit

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ERCC4 mRNA

NCBI chr10:2,926,085...2,958,176
Ensembl chr10:2,920,455...2,955,539

G

ERCC excision repair 6, chromatin remodeling factor

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ERCC6 gene

NCBI chr16:7,771,311...7,841,895
Ensembl chr16:7,771,581...7,841,895

G

ERCC excision repair 6 like, spindle assembly checkpoint helicase

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ERCC6L mRNA
[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of ERCC6L mRNA

PMID:20938992 PMID:24657277

NCBI chr X:71,285,380...71,301,186
Ensembl chr X:71,285,380...71,301,186

G

ERCC excision repair 6 like 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ERCC6L2 mRNA

NCBI chr17:1,055,881...1,323,207
Ensembl chr17:1,222,139...1,316,056

G

ERCC excision repair 8, CSA ubiquitin ligase complex subunit

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ERCC8 mRNA

NCBI chr 2:41,380,901...41,418,294
Ensembl chr 2:41,380,901...41,418,294

G

Ets2 repressor factor

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ERF mRNA

NCBI chr 1:89,957,760...89,966,213
Ensembl chr 1:89,957,760...89,966,213

G

ergosterol biosynthesis 28 homolog

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ERG28 mRNA
Folic Acid results in decreased expression of ERG28 mRNA

PMID:21867686 PMID:22206623

NCBI chr 6:111,205,102...111,214,068
Ensembl chr 6:111,205,103...111,214,068

G

endoplasmic reticulum-golgi intermediate compartment 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ERGIC1 gene
Folic Acid results in decreased expression of ERGIC1 mRNA

PMID:20938992 PMID:25629700

NCBI chr10:17,035,615...17,131,411
Ensembl chr10:17,035,615...17,131,376

G

ERGIC and golgi 2

decreases expression

ISO

Folic Acid results in decreased expression of ERGIC2 mRNA

NCBI chr 4:182,822,225...182,858,392
Ensembl chr 4:182,822,225...182,854,490

G

ERGIC and golgi 3

multiple interactions
increases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ERGIC3 mRNA
Folic Acid results in increased expression of ERGIC3 mRNA

PMID:22206623 PMID:25629700

NCBI chr 3:164,985,108...164,994,897
Ensembl chr 3:164,984,853...164,994,897

G

ERH, mRNA splicing and mitosis factor

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ERH mRNA

NCBI chr 6:106,012,255...106,022,521
Ensembl chr 6:106,012,255...106,022,623

G

exoribonuclease 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ERI1 gene
Folic Acid results in decreased expression of ERI1 mRNA

PMID:20938992 PMID:25629700

NCBI chr16:63,427,412...63,447,521
Ensembl chr16:63,427,403...63,447,896

G

endoplasmic reticulum lectin 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ERLEC1 mRNA

NCBI chr14:108,856,661...108,894,511
Ensembl chr14:108,856,661...108,894,297

G

endoplasmic reticulum metallopeptidase 1

multiple interactions
decreases expression

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of ERMP1 mRNA]
Folic Acid results in decreased expression of ERMP1 mRNA

PMID:22206623 PMID:25629700

NCBI chr 1:236,801,459...236,835,656
Ensembl chr 1:236,801,466...236,839,197

G

endoplasmic reticulum to nucleus signaling 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ERN1 gene

NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,830,428...91,920,791

G

endoplasmic reticulum oxidoreductase 1 alpha

multiple interactions

ISO

[Ethanol co-treated with Folic Acid] results in increased expression of ERO1A mRNA

NCBI chr15:20,974,771...21,010,170
Ensembl chr15:20,972,679...21,018,039

G

endoplasmic reticulum oxidoreductase 1 beta

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of and results in decreased expression of ERO1B; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ERO1B gene
Folic Acid results in decreased expression of ERO1B mRNA

PMID:20938992 PMID:25629700

NCBI chr17:92,913,696...92,987,401
Ensembl chr17:92,814,368...92,987,555

G

endoplasmic reticulum protein 29

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of ERP29 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ERP29 mRNA

PMID:22206623 PMID:25629700

NCBI chr12:40,750,177...40,756,607
Ensembl chr12:40,750,314...40,757,010

G

establishment of sister chromatid cohesion N-acetyltransferase 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ESCO1 gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of ESCO1 mRNA]

PMID:20938992 PMID:22206623

NCBI chr18:1,904,748...1,959,609
Ensembl chr18:1,904,762...1,959,805

G

establishment of sister chromatid cohesion N-acetyltransferase 2

multiple interactions

ISO

[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of ESCO2 mRNA

NCBI chr15:44,210,124...44,230,785
Ensembl chr15:44,210,641...44,231,304
Ensembl chr15:44,210,641...44,231,304

G

esterase D

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ESD mRNA

NCBI chr15:56,453,082...56,472,582
Ensembl chr15:56,453,044...56,473,508

G

ESF1 nucleolar pre-rRNA processing protein homolog

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ESF1 mRNA

NCBI chr 3:147,908,405...147,961,567
Ensembl chr 3:147,908,405...147,961,485

G

extra spindle pole bodies like 1, separase

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ESPL1 mRNA
Folic Acid results in decreased expression of ESPL1 mRNA

PMID:20938992 PMID:21867686

NCBI chr 7:135,302,460...135,329,570
Ensembl chr 7:135,302,716...135,329,570

G

espin

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ESPN gene
Folic Acid results in decreased expression of ESPN mRNA

PMID:20938992 PMID:21867686

NCBI chr 5:167,909,271...167,943,168
Ensembl chr 5:167,909,271...167,942,984

G

estrogen receptor 1

affects expression

ISO

Folic Acid affects the expression of ESR1 mRNA

NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354

G

epithelial splicing regulatory protein 1

multiple interactions
decreases expression

ISO

[Ethanol co-treated with Folic Acid] results in increased expression of ESRP1 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ESRP1 mRNA
Folic Acid results in decreased expression of ESRP1 mRNA

PMID:22206623 PMID:23378141 PMID:25629700

NCBI chr 5:29,224,831...29,279,381
Ensembl chr 5:29,225,360...29,279,278

G

estrogen-related receptor gamma

decreases expression

ISO

Folic Acid results in decreased expression of ESRRG mRNA

NCBI chr13:101,699,043...102,316,877
Ensembl chr13:101,889,706...102,316,877

G

ess-2 splicing factor homolog

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ESS2 mRNA

NCBI chr11:96,580,185...96,596,673
Ensembl chr11:96,580,169...96,590,146

G

extended synaptotagmin 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ESYT1 gene

NCBI chr 7:1,513,381...1,530,836
Ensembl chr 7:1,513,381...1,530,732

G

ETAA1 activator of ATR kinase

decreases expression

ISO

Folic Acid results in decreased expression of ETAA1 mRNA

NCBI chr14:96,500,899...96,515,617
Ensembl chr14:96,500,899...96,517,796

G

eukaryotic translation termination factor 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ETF1 gene
Folic Acid results in decreased expression of ETF1 mRNA

PMID:20938992 PMID:25629700

NCBI chr18:26,776,518...26,804,857
Ensembl chr18:26,777,858...26,804,613

G

electron transfer flavoprotein subunit alpha

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ETFA mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ETFA gene

PMID:20938992 PMID:22206623

NCBI chr 8:64,731,192...64,787,965
Ensembl chr 8:64,731,193...64,788,080

G

electron transfer flavoprotein subunit beta

increases expression

ISO

Folic Acid results in increased expression of ETFB mRNA

NCBI chr 1:102,988,499...103,002,663
Ensembl chr 1:102,988,499...103,002,659

G

electron transfer flavoprotein regulatory factor 1

decreases expression

ISO

Folic Acid results in decreased expression of ETFRF1 mRNA

NCBI chr 4:179,910,651...179,916,095
Ensembl chr 4:179,910,914...179,916,095

G

ETHE1, persulfide dioxygenase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ETHE1 mRNA

NCBI chr 1:89,311,948...89,327,000
Ensembl chr 1:89,311,934...89,326,998

G

enhancer trap locus 4

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of ETL4 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ETL4 mRNA
Folic Acid results in decreased expression of KIAA1217 mRNA

PMID:21867686 PMID:22206623 PMID:25629700

NCBI chr17:87,749,486...88,213,158
Ensembl chr17:87,403,819...88,213,158

G

ethanolamine kinase 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ETNK1 mRNA
Folic Acid results in decreased expression of ETNK1 mRNA

PMID:20938992 PMID:25629700

NCBI chr 4:177,857,001...177,901,278
Ensembl chr 4:177,856,960...177,924,721

G

ETS proto-oncogene 2, transcription factor

affects expression
multiple interactions

ISO

Folic Acid affects the expression of ETS2 mRNA
Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ETS2 mRNA]

PMID:16361273 PMID:22206623

NCBI chr11:48,491,057...48,507,843
Ensembl chr11:48,491,394...48,507,842

G

ETS variant transcription factor 4

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ETV4 mRNA]

NCBI chr10:87,206,977...87,222,202
Ensembl chr10:87,206,977...87,222,318

G

ETS variant transcription factor 6

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ETV6 mRNA]

NCBI chr 4:168,580,405...168,819,817
Ensembl chr 4:168,580,138...168,819,802

G

eva-1 homolog A, regulator of programmed cell death

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of EVA1A mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EVA1A mRNA

PMID:22206623 PMID:25629700

NCBI chr 4:116,151,595...116,200,827
Ensembl chr 4:116,151,173...116,200,827

G

EvC ciliary complex subunit 2

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EVC2 mRNA; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of EVC2 mRNA]
Folic Acid results in increased expression of EVC2 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr14:77,591,581...77,679,286
Ensembl chr14:77,592,560...77,679,262

G

ecotropic viral integration site 2A

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EVI2A mRNA

NCBI chr10:64,983,727...64,987,627
Ensembl chr10:64,983,705...64,999,516

G

ecotropic viral integration site 5-like

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of EVI5L mRNA

NCBI chr12:7,317,474...7,356,445
Ensembl chr12:7,317,515...7,356,616

G

Enah/Vasp-like

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EVL mRNA

NCBI chr 6:133,238,547...133,358,730
Ensembl chr 6:133,238,547...133,358,729

G

envoplakin

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EVPL mRNA

NCBI chr10:101,957,107...101,973,656
Ensembl chr10:101,941,064...101,973,656

G

even-skipped homeobox 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EVX1 gene
Folic Acid results in decreased expression of EVX1 mRNA

PMID:20938992 PMID:21867686

NCBI chr 4:82,747,192...82,751,569
Ensembl chr 4:82,746,993...82,751,569

G

even-skipped homeobox 2

decreases expression

ISO

Folic Acid results in decreased expression of EVX2 mRNA

NCBI chr 3:79,965,630...79,969,700
Ensembl chr 3:79,965,630...79,969,305

G

EWS RNA-binding protein 1

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of EWSR1 mRNA
Folic Acid results in decreased expression of EWSR1 mRNA

PMID:22206623 PMID:25629700

NCBI chr14:84,179,413...84,208,149
Ensembl chr14:84,179,618...84,208,095

G

exonuclease 3'-5' domain containing 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of EXD1 mRNA

NCBI chr 3:126,961,800...126,989,738
Ensembl chr 3:126,961,896...126,989,738

G

exonuclease 3'-5' domain containing 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of and results in decreased expression of EXD2; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of EXD2 gene

NCBI chr 6:105,847,931...105,881,780
Ensembl chr 6:105,848,305...105,883,665

G

exonuclease 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EXO1 mRNA

NCBI chr13:90,341,947...90,366,861
Ensembl chr13:90,342,018...90,366,861

G

exonuclease 5

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EXO5 mRNA

NCBI chr 5:139,779,646...139,782,963
Ensembl chr 5:139,777,987...139,783,034

G

exocyst complex component 1

increases expression

ISO

Folic Acid results in increased expression of EXOC1 mRNA

NCBI chr14:31,965,782...32,014,156
Ensembl chr14:31,965,782...32,014,127

G

exocyst complex component 2

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of EXOC2 mRNA]

NCBI chr17:33,714,949...33,906,901
Ensembl chr17:33,715,008...33,901,944

G

exocyst complex component 3-like 4

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EXOC3L4 mRNA
Folic Acid results in decreased expression of EXOC3L4 mRNA

PMID:21867686 PMID:22206623

NCBI chr 6:136,273,857...136,287,877
Ensembl chr 6:136,273,854...136,287,881

G

exocyst complex component 6B

decreases expression

ISO

Folic Acid results in decreased expression of EXOC6B mRNA

NCBI chr 4:118,652,279...119,107,725
Ensembl chr 4:118,652,279...119,107,683

G

exocyst complex component 7

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EXOC7 gene

NCBI chr10:102,019,805...102,039,333
Ensembl chr10:102,019,806...102,039,447

G

exocyst complex component 8

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EXOC8 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of EXOC8 gene

PMID:20938992 PMID:22206623

NCBI chr19:69,752,387...69,754,876
Ensembl chr19:69,727,231...69,804,820

G

exosome component 10

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of EXOSC10 mRNA]

NCBI chr 5:164,278,414...164,302,067
Ensembl chr 5:164,278,440...164,302,067

G

exosome component 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of EXOSC2 mRNA

NCBI chr 3:35,360,652...35,370,948
Ensembl chr 3:35,360,666...35,371,373

G

exosome component 3

decreases expression

ISO

Folic Acid results in decreased expression of EXOSC3 mRNA

NCBI chr 5:64,369,495...64,374,711
Ensembl chr 5:64,369,495...64,374,902

G

exosome component 4

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of EXOSC4 mRNA]

NCBI chr 7:109,928,491...109,931,233
Ensembl chr 7:109,928,498...109,931,820

G

exosome component 5

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EXOSC5 mRNA

NCBI chr 1:90,295,495...90,305,047
Ensembl chr 1:90,293,797...90,305,046

G

exosome component 6

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EXOSC6 mRNA

NCBI chr19:55,931,523...55,932,937
Ensembl chr19:55,931,523...55,932,937

G

exosome component 8

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EXOSC8 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EXOSC8 gene

PMID:20938992 PMID:22206623

NCBI chr 2:141,080,568...141,087,112
Ensembl chr 2:141,080,568...141,087,229

G

exophilin 5

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of EXPH5 mRNA

NCBI chr 8:62,595,116...62,671,575
Ensembl chr 8:62,595,116...62,671,575

G

exostosin glycosyltransferase 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EXT2 mRNA

NCBI chr 3:100,120,776...100,253,424
Ensembl chr 3:100,120,776...100,253,596

G

exostosin-like glycosyltransferase 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EXTL2 mRNA

NCBI chr 2:206,607,106...206,631,861
Ensembl chr 2:206,607,151...206,631,861

G

exostosin-like glycosyltransferase 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of EXTL3 mRNA

NCBI chr15:43,469,293...43,559,760
Ensembl chr15:43,471,366...43,495,356

G

EYA transcriptional coactivator and phosphatase 1

increases expression

ISO

Folic Acid results in increased expression of EYA1 mRNA

NCBI chr 5:9,646,599...9,884,609
Ensembl chr 5:9,646,591...9,884,614

G

enhancer of zeste 1 polycomb repressive complex 2 subunit

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of EZH1 mRNA
Folic Acid results in decreased expression of EZH1 mRNA

PMID:22206623 PMID:25629700

NCBI chr10:86,626,307...86,662,257
Ensembl chr10:86,626,308...86,652,620

G

ezrin

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EZR mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EZR mRNA

PMID:20938992 PMID:22206623

NCBI chr 1:49,373,033...49,416,573
Ensembl chr 1:49,373,035...49,416,573

G

F11 receptor

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of F11R mRNA

NCBI chr13:86,406,229...86,429,819
Ensembl chr13:86,406,218...86,429,816

G

coagulation factor II, thrombin

affects expression

ISO

Folic Acid affects the expression of F2 mRNA

NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:98,051,960...98,065,246

G

coagulation factor II (thrombin) receptor

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of F2R mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of F2R gene

PMID:20938992 PMID:22206623

NCBI chr 2:28,604,066...28,620,579
Ensembl chr 2:28,604,066...28,620,579

G

coagulation factor III, tissue factor

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of F3 mRNA

NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:212,511,680...212,523,369

G

coagulation factor V

increases expression

ISO

Folic Acid results in increased expression of F5 mRNA

NCBI chr13:79,046,657...79,116,247
Ensembl chr13:79,046,448...79,116,247

G

coagulation factor VII

increases expression

ISO

Folic Acid results in increased expression of F7 mRNA

NCBI chr16:83,191,896...83,202,775
Ensembl chr16:83,191,914...83,202,738

G

coagulation factor IX

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of F9 mRNA
Folic Acid results in decreased expression of F9 mRNA

PMID:22206623 PMID:25629700

NCBI chr X:143,388,642...143,433,143
Ensembl chr X:143,388,621...143,433,146

G

fatty acid 2-hydroxylase

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of FA2H; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of FA2H gene; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FA2H mRNA

NCBI chr19:56,222,240...56,273,480
Ensembl chr19:56,222,242...56,273,623

G

FA core complex associated protein 20

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FAAP20 mRNA

NCBI chr 5:171,083,328...171,097,599
Ensembl chr 5:171,087,847...171,097,599

G

fatty acid binding protein 1

increases expression

ISO

Folic Acid results in increased expression of FABP1 mRNA

NCBI chr 4:104,744,302...104,753,119
Ensembl chr 4:104,744,309...104,753,113

G

fatty acid binding protein 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of FABP3 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FABP3 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of FABP3 gene

PMID:20938992 PMID:22206623

NCBI chr 5:147,936,027...147,942,870
Ensembl chr 5:147,936,119...147,942,881

G

fatty acid binding protein 4

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FABP4 mRNA; [Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of FABP4 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FABP4 mRNA

PMID:20938992 PMID:22206623 PMID:29127188

NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:93,488,271...93,492,972

G

fatty acid binding protein 5

multiple interactions

EXP
ISO

[Folic Acid deficiency co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of FABP5 protein
[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of FABP5 mRNA

PMID:19566968 PMID:33549593

NCBI chr 2:93,672,451...93,676,186
Ensembl chr 2:93,672,458...93,676,127

G

fatty acid binding protein 7

multiple interactions

ISO

[Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of FABP7 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FABP7 mRNA

PMID:20938992 PMID:29127188

NCBI chr20:37,667,125...37,673,299
Ensembl chr20:37,669,601...37,675,907

G

Fas associated via death domain

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of FADD mRNA; Folic Acid results in decreased expression of FADD protein
Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in increased expression of FADD protein]

PMID:25629700 PMID:29068127

NCBI chr 1:209,169,245...209,175,423
Ensembl chr 1:209,169,318...209,174,976

G

fatty acid desaturase 1

multiple interactions
increases activity

ISO
EXP

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of FADS1 gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of FADS1 mRNA]
Folic Acid results in increased activity of FADS1 protein
[Folic Acid co-treated with Vitamin B 12 deficiency] results in decreased expression of FADS1 mRNA; Folic Acid inhibits the reaction [[Fatty Acids, Omega-3 co-treated with Vitamin B 12 deficiency] results in decreased expression of FADS1 mRNA]; Folic Acid promotes the reaction [[Vitamin B 12 deficiency co-treated with Fatty Acids, Omega-3] results in decreased activity of FADS1 protein]; Vitamin B 12 deficiency promotes the reaction [Folic Acid results in increased activity of FADS1 protein]

PMID:20938992 PMID:22133376 PMID:22206623

NCBI chr 1:216,252,605...216,267,618
Ensembl chr 1:216,252,602...216,267,615

G

fatty acid desaturase 2

multiple interactions
increases expression
decreases activity

ISO
EXP

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of FADS2 gene
[Vitamin B 12 deficiency co-treated with Folic Acid] results in decreased activity of FADS2 protein; Folic Acid inhibits the reaction [[Vitamin B 12 deficiency co-treated with Fatty Acids, Omega-3] results in decreased activity of FADS2 protein]
Folic Acid results in increased expression of FADS2 mRNA
Folic Acid results in decreased activity of FADS2 protein

PMID:20938992 PMID:22133376 PMID:25629700

NCBI chr 1:216,132,277...216,172,190
Ensembl chr 1:216,133,676...216,172,066

G

fatty acid desaturase 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FADS3 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of FADS3; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of FADS3 gene; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FADS3 mRNA

PMID:20938992 PMID:22206623

NCBI chr 1:216,110,547...216,127,431
Ensembl chr 1:216,110,201...216,141,758

G

Fas associated factor 1

decreases expression

ISO

Folic Acid results in decreased expression of FAF1 mRNA

NCBI chr 5:129,654,677...130,018,604
Ensembl chr 5:129,654,445...130,020,516

G

Fas associated factor family member 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of FAF2 gene

NCBI chr17:9,952,329...9,994,596
Ensembl chr17:9,952,329...9,994,711

G

fumarylacetoacetate hydrolase

decreases expression

ISO

Folic Acid results in decreased expression of FAH mRNA

NCBI chr 1:147,957,931...147,980,708
Ensembl chr 1:147,957,935...147,981,046

G

fumarylacetoacetate hydrolase domain containing 1

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FAHD1 mRNA
Folic Acid results in decreased expression of FAHD1 mRNA

PMID:22206623 PMID:25629700

NCBI chr10:14,378,058...14,379,497
Ensembl chr10:14,378,120...14,379,867

G

Fas apoptotic inhibitory molecule 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of FAIM2 mRNA

NCBI chr 7:132,512,095...132,539,192
Ensembl chr 7:132,512,210...132,538,026

G

family with sequence similarity 107, member A

increases expression

ISO

Folic Acid results in increased expression of FAM107A mRNA

NCBI chr15:19,038,726...19,060,644
Ensembl chr15:19,038,616...19,065,219

G

family with sequence similarity 107, member B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of FAM107B mRNA

NCBI chr17:79,387,795...79,594,165
Ensembl chr17:79,387,795...79,594,288

G

family with sequence similarity 110, member D

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of FAM110D gene

NCBI chr 5:151,754,773...151,757,743
Ensembl chr 5:151,753,891...151,757,768

G

FAM111 trypsin like peptidase A

decreases expression

ISO

Folic Acid results in decreased expression of FAM111A mRNA

NCBI chr 1:219,065,542...219,081,213
Ensembl chr 1:219,065,601...219,081,211

G

family with sequence similarity 114, member A1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FAM114A1 mRNA

NCBI chr14:43,629,349...43,699,800
Ensembl chr14:43,629,375...43,699,800

G

family with sequence similarity 114, member A2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FAM114A2 mRNA

NCBI chr10:42,162,295...42,197,307
Ensembl chr10:42,162,295...42,197,257

G

family with sequence similarity 117, member B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of FAM117B mRNA

NCBI chr 9:68,834,334...68,902,543
Ensembl chr 9:68,834,354...68,902,543

G

family with sequence similarity 118, member A

decreases expression

ISO

Folic Acid results in decreased expression of FAM118A mRNA

NCBI chr 7:118,032,313...118,058,888
Ensembl chr 7:118,032,444...118,058,887

G

family with sequence similarity 118, member B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FAM118B mRNA

NCBI chr 8:41,824,522...41,875,190
Ensembl chr 8:41,824,158...41,846,256

G

family with sequence similarity 120 member A

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FAM120A mRNA
Folic Acid results in decreased expression of FAM120A mRNA

PMID:22206623 PMID:25629700

NCBI chr17:15,890,151...15,981,337
Ensembl chr17:15,890,605...15,981,332

G

family with sequence similarity 120 member B

decreases expression

ISO

Folic Acid results in decreased expression of FAM120B mRNA

NCBI chr 1:64,993,104...65,058,160
Ensembl chr 1:65,012,060...65,058,160

G

family with sequence similarity 124 member A

decreases expression

ISO

Folic Acid results in decreased expression of FAM124A mRNA

NCBI chr15:40,975,789...41,031,069
Ensembl chr15:40,975,877...41,029,628

G

family with sequence similarity 124 member B

decreases expression

ISO

Folic Acid results in decreased expression of FAM124B mRNA

NCBI chr 9:88,961,377...88,981,976
Ensembl chr 9:88,961,377...88,981,976

G

family with sequence similarity 131, member B

decreases expression

ISO

Folic Acid results in decreased expression of FAM131B mRNA

NCBI chr 4:72,167,667...72,176,924
Ensembl chr 4:72,165,578...72,176,858

G

family with sequence similarity 131, member C

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of FAM131C gene

NCBI chr 5:158,957,444...158,973,773
Ensembl chr 5:158,957,451...158,974,019

G

family with sequence similarity 135, member A

decreases expression

ISO

Folic Acid results in decreased expression of FAM135A mRNA

NCBI chr 9:33,916,449...33,997,140
Ensembl chr 9:33,916,449...33,997,051

G

family with sequence similarity 13, member A

multiple interactions

ISO

[Ethanol co-treated with Folic Acid] results in increased expression of FAM13A mRNA

NCBI chr 4:89,386,685...89,485,940
Ensembl chr 4:89,388,569...89,485,988

G

family with sequence similarity 149, member A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FAM149A mRNA

NCBI chr16:53,587,841...53,647,072
Ensembl chr16:53,587,841...53,647,072

G

family with sequence similarity 151, member A

increases expression

ISO

Folic Acid results in increased expression of FAM151A mRNA

NCBI chr 5:126,743,624...126,756,375
Ensembl chr 5:126,743,555...126,756,373

G

family with sequence similarity 162, member A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FAM162A mRNA

NCBI chr11:78,186,260...78,215,186
Ensembl chr11:78,185,852...78,216,560

G

family with sequence similarity 163, member A

decreases expression

ISO

Folic Acid results in decreased expression of FAM163A mRNA

NCBI chr13:70,813,129...70,891,410
Ensembl chr13:70,813,134...70,891,316

G

family with sequence similarity 168, member A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of FAM168A mRNA

NCBI chr 1:164,469,447...164,615,542
Ensembl chr 1:164,469,471...164,615,506

G

family with sequence similarity 168, member B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FAM168B mRNA

NCBI chr 9:44,501,466...44,534,571
Ensembl chr 9:44,502,584...44,534,974

G

family with sequence similarity 169, member A

decreases expression

ISO

Folic Acid results in decreased expression of FAM169A mRNA

NCBI chr 2:30,115,307...30,175,972
Ensembl chr 2:30,119,381...30,175,962

G

family with sequence similarity 174, member A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FAM174A mRNA

NCBI chr 9:103,190,144...103,208,419
Ensembl chr 9:103,190,127...103,209,228

G

family with sequence similarity 174, member B

decreases expression

ISO

Folic Acid results in decreased expression of FAM174B mRNA

NCBI chr 1:136,925,162...137,006,082
Ensembl chr 1:136,925,151...137,035,589

G

family with sequence similarity 174 member C

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FAM174C mRNA

NCBI chr 7:10,182,653...10,184,363
Ensembl chr 7:10,182,653...10,184,363

G

family with sequence similarity 178, member B

decreases expression

ISO

Folic Acid results in decreased expression of FAM178B mRNA

NCBI chr 9:46,301,734...46,409,571
Ensembl chr 9:46,301,734...46,410,686

G

family with sequence similarity 209

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of FAM209 mRNA

NCBI chr 3:181,658,479...181,660,164
Ensembl chr 3:181,658,461...181,660,164

G

FAM20B, glycosaminoglycan xylosylkinase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FAM20B mRNA

NCBI chr13:71,351,834...71,390,192
Ensembl chr13:71,351,834...71,387,882

G

family with sequence similarity 220, member A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FAM220A mRNA

NCBI chr12:16,111,593...16,127,584
Ensembl chr12:16,109,425...16,133,421

G

family with sequence similarity 234, member A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FAM234A mRNA

NCBI chr10:15,736,741...15,768,043
Ensembl chr10:15,736,742...15,749,835

G

family with sequence similarity 234, member B

decreases expression

ISO

Folic Acid results in decreased expression of FAM234B mRNA

NCBI chr 4:169,779,651...169,854,024
Ensembl chr 4:169,779,737...169,828,678

G

family with sequence similarity 32, member A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FAM32A mRNA

NCBI chr16:17,637,078...17,641,448
Ensembl chr16:17,637,087...17,641,399

G

FAM3 metabolism regulating signaling molecule A

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FAM3A mRNA
Folic Acid results in decreased expression of FAM3A mRNA

PMID:22206623 PMID:25629700

NCBI chr X:157,317,993...157,326,640
Ensembl chr X:157,317,990...157,326,612

G

FAM3 metabolism regulating signaling molecule B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FAM3B mRNA

NCBI chr11:50,300,926...50,333,296
Ensembl chr11:50,300,926...50,347,339

G

FAM3 metabolism regulating signaling molecule D

multiple interactions
increases expression

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of FAM3D mRNA]
Folic Acid results in increased expression of FAM3D mRNA

PMID:22206623 PMID:25629700

NCBI chr15:18,969,737...19,003,276
Ensembl chr15:18,969,737...19,004,701

G

family with sequence similarity 43, member A

decreases expression

ISO

Folic Acid results in decreased expression of FAM43A mRNA

NCBI chr11:83,633,165...83,636,313
Ensembl chr11:83,633,154...83,695,297

G

family with sequence similarity 50, member A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of FAM50A mRNA

NCBI chr X:157,246,533...157,253,650
Ensembl chr X:157,246,533...157,253,650

G

family with sequence similarity 53, member C

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of FAM53C mRNA

NCBI chr18:26,638,781...26,652,294
Ensembl chr18:26,638,062...26,652,290

G

family with sequence similarity 83, member E

increases expression

ISO

Folic Acid results in increased expression of FAM83E mRNA

NCBI chr 1:105,328,297...105,337,641
Ensembl chr 1:105,328,247...105,337,638

G

family with sequence similarity 89, member B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of FAM89B mRNA

NCBI chr 1:212,445,101...212,447,164
Ensembl chr 1:212,445,102...212,446,738

G

family with sequence similarity 8, member A1

decreases expression

ISO

Folic Acid results in decreased expression of FAM8A1 mRNA

NCBI chr17:18,232,834...18,241,736
Ensembl chr17:18,232,834...18,241,703

G

family with sequence similarity 98, member A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FAM98A mRNA

NCBI chr 6:25,626,108...25,640,767
Ensembl chr 6:25,625,984...25,640,767

G

FA complementation group A

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FANCA mRNA

NCBI chr19:68,210,562...68,271,080
Ensembl chr19:68,212,643...68,271,019

G

FA complementation group D2

multiple interactions

ISO

[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of FANCD2 mRNA

NCBI chr 4:148,234,633...148,299,035
Ensembl chr 4:148,234,708...148,299,035

G

FA complementation group F

decreases expression

ISO

Folic Acid results in decreased expression of FANCF mRNA

NCBI chr 1:110,585,054...110,587,870
Ensembl chr 1:110,576,389...110,587,863

G

FA complementation group L

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of FANCL mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FANCL mRNA

PMID:22206623 PMID:25629700

NCBI chr14:104,449,403...104,515,297
Ensembl chr14:104,394,590...104,515,297

G

fibroblast activation protein, alpha

increases expression
multiple interactions

ISO

Folic Acid results in increased expression of FAP mRNA
Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of FAP mRNA]

PMID:22206623 PMID:25629700

NCBI chr 3:67,547,398...67,616,271
Ensembl chr 3:67,546,921...67,617,601

G

fatty acyl CoA reductase 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FAR1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of FAR1 gene
Folic Acid results in decreased expression of FAR1 mRNA

PMID:20938992 PMID:25629700

NCBI chr 1:177,078,973...177,140,363
Ensembl chr 1:177,079,150...177,161,696

G

FERM, ARH/RhoGEF and pleckstrin domain protein 1

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FARP1 mRNA
Folic Acid results in decreased expression of FARP1 mRNA

PMID:22206623 PMID:25629700

NCBI chr15:104,531,196...104,770,148
Ensembl chr15:104,531,813...104,770,147

G

FERM, ARH/RhoGEF and pleckstrin domain protein 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FARP2 mRNA

NCBI chr 9:101,501,061...101,609,092
Ensembl chr 9:101,501,102...101,609,086

G

phenylalanyl-tRNA synthetase 2, mitochondrial

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of FARS2 gene

NCBI chr17:28,524,737...28,951,818
Ensembl chr17:28,524,738...28,951,591

G

phenylalanyl-tRNA synthetase subunit alpha

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of FARSA mRNA
Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of FARSA mRNA]

PMID:22206623 PMID:25629700

NCBI chr19:40,196,255...40,205,830
Ensembl chr19:40,173,716...40,205,823

G

Fas cell surface death receptor

affects expression
multiple interactions

ISO

Folic Acid affects the expression of FAS mRNA
Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in increased expression of FAS protein]

PMID:16611376 PMID:29068127

NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104

G

fatty acid synthase

multiple interactions
increases expression

ISO
EXP

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of FASN gene
Folic Acid deficiency results in increased expression of FASN mRNA
[Choline co-treated with Betaine co-treated with Vitamin B 12 co-treated with Folic Acid] affects the reaction [[Dietary Fats co-treated with Dietary Sucrose] affects the methylation of FASN promoter]; Folic Acid inhibits the reaction [acetamiprid results in increased expression of FASN protein]

PMID:20938992 PMID:22648174 PMID:30153273 PMID:35124148

NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583

G

Fas-activated serine/threonine kinase

decreases expression
increases expression

ISO

Folic Acid results in decreased expression of FASTK mRNA
Folic Acid results in increased expression of FASTK mRNA

PMID:21867686 PMID:25629700

NCBI chr 4:11,624,697...11,628,769
Ensembl chr 4:11,624,689...11,629,867

G

FAST kinase domains 1

decreases expression

ISO

Folic Acid results in decreased expression of FASTKD1 mRNA

NCBI chr 3:74,857,539...74,883,483
Ensembl chr 3:74,845,261...74,883,367

G

FAST kinase domains 5

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of FASTKD5 mRNA

NCBI chr 3:138,283,315...138,300,803
Ensembl chr 3:138,272,928...138,301,291

G

FAT atypical cadherin 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of FAT1 gene

NCBI chr16:53,909,759...54,029,175
Ensembl chr16:53,909,556...54,028,609

G

FAT atypical cadherin 2

decreases expression

ISO

Folic Acid results in decreased expression of FAT2 mRNA

NCBI chr10:39,864,765...39,957,027
Ensembl chr10:39,864,766...39,956,902

G

FAT atypical cadherin 4

decreases expression
increases expression

ISO

Folic Acid results in decreased expression of FAT4 mRNA
Folic Acid results in increased expression of FAT4 mRNA

PMID:21867686 PMID:25629700

NCBI chr 2:123,855,289...123,984,716
Ensembl chr 2:123,855,289...123,984,716

G

fatty acid hydroxylase domain containing 2

multiple interactions

ISO

[Ethanol co-treated with Folic Acid] results in increased expression of FAXDC2 mRNA

NCBI chr10:42,747,323...42,772,156
Ensembl chr10:42,747,524...42,781,458

G

F-box DNA helicase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FBH1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of FBH1 gene

PMID:20938992 PMID:22206623

NCBI chr17:71,659,351...71,697,431
Ensembl chr17:71,659,249...71,697,432

G

fibrillarin

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FBL mRNA

NCBI chr 1:92,597,407...92,606,507
Ensembl chr 1:92,597,258...92,606,506

G

filamin binding LIM protein 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of FBLIM1 mRNA

NCBI chr 5:159,167,004...159,198,578
Ensembl chr 5:159,167,004...159,196,853

G

fibulin 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FBLN1 mRNA

NCBI chr 7:118,190,347...118,269,965
Ensembl chr 7:118,190,478...118,269,965

G

fibulin 2

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of FBLN2 gene
Folic Acid results in decreased expression of FBLN2 mRNA

PMID:20938992 PMID:25629700

NCBI chr 4:125,261,464...125,321,030
Ensembl chr 4:125,261,607...125,321,029

G

fibulin 5

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FBLN5 mRNA

NCBI chr 6:126,664,100...126,742,847
Ensembl chr 6:126,664,100...126,746,296

G

fibrillin 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FBN1 mRNA

NCBI chr 3:133,007,693...133,204,277
Ensembl chr 3:133,008,361...133,204,283

G

fibrillin 2

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FBN2 mRNA
Folic Acid results in decreased expression of FBN2 mRNA

PMID:20938992 PMID:25629700

NCBI chr18:53,696,197...53,901,992
Ensembl chr18:53,697,708...53,902,191

G

fructose-bisphosphatase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FBP1 mRNA

NCBI chr17:2,212,941...2,235,749
Ensembl chr17:2,213,492...2,235,746

G

fructose-bisphosphatase 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FBP2 mRNA

NCBI chr17:2,241,767...2,259,371
Ensembl chr17:2,241,975...2,259,366

G

fibrosin-like 1

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of FBRSL1 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FBRSL1 mRNA

PMID:22206623 PMID:25629700

NCBI chr12:51,891,211...51,979,715
Ensembl chr12:51,960,790...51,979,361

G

F-box and leucine-rich repeat protein 18

decreases expression

ISO

Folic Acid results in decreased expression of FBXL18 mRNA

NCBI chr12:16,781,901...16,812,728
Ensembl chr12:16,789,665...16,814,240

G

F-box and leucine-rich repeat protein 20

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FBXL20 mRNA
Folic Acid results in decreased expression of FBXL20 mRNA

PMID:22206623 PMID:25629700

NCBI chr10:83,577,038...83,640,022
Ensembl chr10:83,577,038...83,639,977

G

F-box and leucine-rich repeat protein 21

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of FBXL21 gene

NCBI chr17:8,063,731...8,082,920
Ensembl chr17:8,066,565...8,078,644

G

F-box and leucine-rich repeat protein 3

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FBXL3 mRNA
Folic Acid results in decreased expression of FBXL3 mRNA

PMID:22206623 PMID:25629700

NCBI chr15:86,321,504...86,341,387
Ensembl chr15:86,321,504...86,341,387

G

F-box and leucine-rich repeat protein 4

decreases expression

ISO

Folic Acid results in decreased expression of FBXL4 mRNA

NCBI chr 5:40,752,513...40,826,154
Ensembl chr 5:40,752,521...40,850,826

G

F-box and leucine-rich repeat protein 5

decreases expression

ISO

Folic Acid results in decreased expression of FBXL5 mRNA

NCBI chr14:71,517,452...71,559,850
Ensembl chr14:71,480,270...71,560,652

G

F-box and leucine-rich repeat protein 6

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FBXL6 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of FBXL6 gene
Folic Acid results in decreased expression of FBXL6 mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr 7:110,140,243...110,143,176
Ensembl chr 7:110,140,244...110,143,141

G

F-box and leucine-rich repeat protein 8

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FBXL8 mRNA

NCBI chr19:50,048,221...50,057,191
Ensembl chr19:50,052,393...50,057,453

G

F-box protein 11

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FBXO11 mRNA

NCBI chr 6:12,240,348...12,316,223
Ensembl chr 6:12,239,801...12,316,221

G

F-box protein 17

decreases expression

ISO

Folic Acid results in decreased expression of FBXO17 mRNA

NCBI chr 1:93,129,776...93,151,983
Ensembl chr 1:93,129,849...93,151,981

G

F-box protein 2

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of FBXO2 mRNA]

NCBI chr 5:163,876,079...163,881,508
Ensembl chr 5:163,875,757...163,881,508

G

F-box protein 22

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of FBXO22 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of FBXO22 mRNA

PMID:21867686 PMID:22206623

NCBI chr 8:64,476,034...64,492,063
Ensembl chr 8:64,475,957...64,492,062

G

F-box protein 24

increases expression

ISO

Folic Acid results in increased expression of FBXO24 mRNA

NCBI chr12:24,709,449...24,719,851
Ensembl chr12:24,709,468...24,719,848

G

F-box protein 25

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of FBXO25 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FBXO25 mRNA

PMID:22206623 PMID:25629700

NCBI chr16:82,370,123...82,404,002
Ensembl chr16:82,370,059...82,403,919

G

F-box protein 3

decreases expression

ISO

Folic Acid results in decreased expression of FBXO3 mRNA

NCBI chr 3:110,872,185...110,904,479
Ensembl chr 3:110,872,220...110,904,479

G

F-box protein 32

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FBXO32 mRNA

NCBI chr 7:91,620,925...91,654,491
Ensembl chr 7:91,620,925...91,654,491

G

F-box protein 36

increases expression

ISO

Folic Acid results in increased expression of FBXO36 mRNA

NCBI chr 9:93,490,618...93,555,298
Ensembl chr 9:93,489,865...93,555,305

G

F-box protein 38

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FBXO38 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of FBXO38 gene

PMID:20938992 PMID:22206623

NCBI chr18:58,227,253...58,274,320
Ensembl chr18:58,227,262...58,274,262

G

F-box protein 39

decreases expression

ISO

Folic Acid results in decreased expression of FBXO39 mRNA

NCBI chr10:57,428,259...57,433,468
Ensembl chr10:57,430,848...57,433,467

G

F-box protein 4

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of FBXO4 mRNA]

NCBI chr 2:54,902,394...54,915,388
Ensembl chr 2:54,902,394...54,915,388

G

F-box protein 42

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of FBXO42 gene

NCBI chr 5:158,734,165...158,792,560
Ensembl chr 5:158,734,175...158,792,565

G

F-box protein 43

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of FBXO43 gene

NCBI chr 7:69,218,298...69,231,873
Ensembl chr 7:69,218,299...69,230,310

G

F-box protein 46

decreases expression

ISO

Folic Acid results in decreased expression of FBXO46 mRNA

NCBI chr 1:87,898,029...87,914,615
Ensembl chr 1:87,897,888...87,926,021

G

F-box protein 8

decreases expression

ISO

Folic Acid results in decreased expression of FBXO8 mRNA

NCBI chr16:38,676,011...38,721,849
Ensembl chr16:38,676,014...38,721,906

G

f-box protein 9

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FBXO9 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of FBXO9 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of FBXO9 gene

PMID:20938992 PMID:22206623

NCBI chr 8:87,838,787...87,864,362
Ensembl chr 8:87,838,789...87,864,504

G

F-box and WD repeat domain containing 11

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FBXW11 mRNA

NCBI chr10:17,737,181...17,834,834
Ensembl chr10:17,720,444...17,834,834

G

F-box and WD repeat domain containing 12

increases expression

ISO

Folic Acid results in increased expression of FBXW13 mRNA

NCBI chr 8:118,660,777...118,680,565
Ensembl chr 8:118,660,605...118,680,572

G

F-box and WD repeat domain containing 2

decreases expression

ISO

Folic Acid results in decreased expression of FBXW2 mRNA

NCBI chr 3:38,486,358...38,511,683
Ensembl chr 3:38,486,362...38,511,667

G

F-box and WD repeat domain containing 5

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of FBXW5 mRNA

NCBI chr 3:28,720,670...28,725,237
Ensembl chr 3:28,720,778...28,725,235

G

Fc alpha receptor

increases expression

ISO

Folic Acid results in increased expression of FCAR mRNA

NCBI chr 1:78,669,119...78,703,223

G

Fc epsilon receptor Ig

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FCER1G mRNA
Folic Acid results in decreased expression of FCER1G mRNA

PMID:20938992 PMID:25629700

NCBI chr13:86,181,908...86,186,766
Ensembl chr13:86,181,908...86,186,859

G

Fcf1 rRNA-processing protein

decreases expression

ISO

Folic Acid results in decreased expression of FCF1 mRNA

NCBI chr 6:110,348,854...110,360,715
Ensembl chr 6:110,348,845...110,372,221

G

Fc gamma receptor 1A

increases expression

ISO

Folic Acid results in increased expression of FCGR1 mRNA

NCBI chr 2:186,539,941...186,548,941
Ensembl chr 2:186,539,942...186,548,858

G

Fc gamma receptor 2A

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FCGR3 mRNA

NCBI chr13:85,813,516...85,830,269
Ensembl chr13:85,855,437...85,864,394
Ensembl chr13:85,855,437...85,864,394

G

Fc gamma receptor 3A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FCGR4 mRNA

NCBI chr13:85,782,636...85,792,656
Ensembl chr13:85,782,490...85,792,651

G

Fc gamma receptor and transporter

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FCGRT mRNA

NCBI chr 1:104,710,902...104,720,685
Ensembl chr 1:104,710,909...104,720,532

G

FCH and double SH3 domains 2

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FCHSD2 mRNA
Folic Acid results in decreased expression of FCHSD2 mRNA

PMID:22206623 PMID:25629700

NCBI chr 1:164,775,916...165,097,391
Ensembl chr 1:164,775,926...165,097,391

G

Fc mu receptor

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of FCMR gene

NCBI chr13:44,889,628...44,903,926
Ensembl chr13:44,889,697...44,906,314

G

ficolin B

decreases expression

ISO

Folic Acid results in decreased expression of FCNB mRNA

NCBI chr 3:31,791,750...31,800,188
Ensembl chr 3:31,791,750...31,800,188

G

Fc receptor-like 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FCRL2 mRNA

NCBI chr 2:174,992,226...175,005,177
Ensembl chr 2:174,992,226...175,004,967

G

Fc receptor-like B

increases expression

ISO

Folic Acid results in increased expression of FCRLB mRNA

NCBI chr13:85,681,403...85,689,880
Ensembl chr13:85,682,472...85,688,707

G

farnesyl diphosphate farnesyl transferase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FDFT1 mRNA

NCBI chr15:41,588,114...41,616,168
Ensembl chr15:41,588,117...41,616,168

G

farnesyl diphosphate synthase

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of FDPS mRNA]

NCBI chr 2:176,795,192...176,804,816
Ensembl chr 2:176,795,192...176,807,136

G

ferredoxin 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FDX1 mRNA

NCBI chr 8:61,164,839...61,183,645
Ensembl chr 8:61,164,839...61,183,583

G

ferredoxin 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FDX2 mRNA

NCBI chr 8:27,881,091...27,886,230
Ensembl chr 8:27,881,091...27,886,015

G

ferredoxin reductase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FDXR mRNA

NCBI chr10:101,006,845...101,015,582
Ensembl chr10:101,006,849...101,015,542

G

ferrochelatase

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of FECH mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of FECH gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of FECH mRNA]

PMID:20938992 PMID:22206623

NCBI chr18:60,215,325...60,248,525
Ensembl chr18:60,215,325...60,249,546

G

fem-1 homolog A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FEM1A mRNA

NCBI chr 9:1,178,857...1,181,063
Ensembl chr 9:1,177,543...1,188,006

G

fem-1 homolog C

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of FEM1C gene

NCBI chr18:41,419,511...41,445,300
Ensembl chr18:41,419,511...41,445,300

G

fer-1-like family member 4

decreases expression

ISO

Folic Acid results in decreased expression of FER1L4 mRNA

NCBI chr 3:164,996,183...165,031,719
Ensembl chr 3:164,996,183...165,031,719

G

FERM domain containing kindlin 2

decreases expression

ISO

Folic Acid results in decreased expression of FERMT2 mRNA

NCBI chr15:21,162,603...21,257,995
Ensembl chr15:21,162,605...21,258,115

G

FERRY endosomal RAB5 effector complex subunit 3

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of D6WSU163E mRNA
Folic Acid results in decreased expression of D6WSU163E mRNA

PMID:22206623 PMID:25629700

NCBI chr 4:161,458,942...161,494,213
Ensembl chr 4:161,458,931...161,493,075

G

FES proto-oncogene, tyrosine kinase

multiple interactions
decreases expression

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of FES mRNA]
Folic Acid results in decreased expression of FES mRNA

PMID:22206623 PMID:25629700

NCBI chr 1:143,746,945...143,756,181
Ensembl chr 1:143,746,945...143,756,181

G

fetuin B

increases expression

ISO

Folic Acid results in increased expression of FETUB mRNA

NCBI chr11:91,586,750...91,599,789
Ensembl chr11:91,586,748...91,599,310

G

fasciculation and elongation protein zeta 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FEZ1 mRNA

NCBI chr 8:44,733,288...44,778,519
Ensembl chr 8:44,733,300...44,784,097

G

fasciculation and elongation protein zeta 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of FEZ2 mRNA

NCBI chr 6:22,406,685...22,446,745
Ensembl chr 6:22,406,632...22,447,041

G

Fez family zinc finger 1

decreases expression

ISO

Folic Acid results in decreased expression of FEZF1 mRNA

NCBI chr 4:52,728,385...52,733,315
Ensembl chr 4:52,728,391...52,731,718

G

Fez family zinc finger 2

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of FEZF2 gene
Folic Acid results in increased expression of FEZF2 mRNA

PMID:20938992 PMID:25629700

NCBI chr15:15,199,045...15,207,982
Ensembl chr15:15,204,193...15,207,982

G

free fatty acid receptor 4

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FFAR4 mRNA

NCBI chr 1:245,286,009...245,304,029
Ensembl chr 1:245,285,883...245,304,031

G

fibrinogen alpha chain

increases expression
multiple interactions

ISO

Folic Acid results in increased expression of FGA mRNA
Folic Acid results in increased expression of FGA protein
[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of FGA mRNA; icariin inhibits the reaction [Folic Acid results in increased expression of FGA protein]

PMID:17868486 PMID:20938992 PMID:38272249

NCBI chr 2:170,672,169...170,679,572
Ensembl chr 2:170,672,012...170,679,577

G

fibrinogen beta chain

multiple interactions
increases expression

ISO

icariin inhibits the reaction [Folic Acid results in increased expression of FGB protein]

NCBI chr 2:170,693,966...170,700,875
Ensembl chr 2:170,692,965...170,705,434

G

FYVE, RhoGEF and PH domain containing 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FGD1 mRNA

NCBI chr X:23,466,791...23,509,773
Ensembl chr X:23,467,530...23,509,979

G

FYVE, RhoGEF and PH domain containing 2

decreases expression

ISO

Folic Acid results in decreased expression of FGD2 mRNA

NCBI chr20:7,426,407...7,443,207
Ensembl chr20:7,426,414...7,443,207

G

FYVE, RhoGEF and PH domain containing 3

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FGD3 mRNA

NCBI chr17:15,531,237...15,593,678
Ensembl chr17:15,543,236...15,593,676

G

FYVE, RhoGEF and PH domain containing 4

decreases expression

ISO

Folic Acid results in decreased expression of FGD4 mRNA

NCBI chr11:97,904,182...98,055,190
Ensembl chr11:97,904,182...98,055,190

G

fibroblast growth factor 10

decreases expression

ISO

Folic Acid results in decreased expression of FGF10 mRNA

NCBI chr 2:52,533,939...52,610,980
Ensembl chr 2:52,533,939...52,610,980

G

fibroblast growth factor 11

decreases expression

ISO

Folic Acid results in decreased expression of FGF11 mRNA

NCBI chr10:55,015,232...55,020,773
Ensembl chr10:55,016,411...55,020,454

G

fibroblast growth factor 12

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of FGF12; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of FGF12 gene; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FGF12 mRNA
Folic Acid results in decreased expression of FGF12 mRNA

PMID:20938992 PMID:25629700

NCBI chr11:85,501,947...86,069,543
Ensembl chr11:85,501,936...86,069,543

G

fibroblast growth factor 2

increases expression

ISO

Folic Acid results in increased expression of FGF2 mRNA

NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493

G

fibroblast growth factor 21

multiple interactions

ISO

[Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of FGF21 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FGF21 mRNA

PMID:20938992 PMID:29127188

NCBI chr 1:105,219,825...105,221,376
Ensembl chr 1:105,219,825...105,232,056

G

fibroblast growth factor 23

increases expression

ISO

Folic Acid results in increased expression of FGF23 mRNA; Folic Acid results in increased expression of FGF23 protein

NCBI chr 4:161,600,439...161,609,991
Ensembl chr 4:161,600,383...161,609,991

G

fibroblast growth factor 4

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of FGF4 gene

NCBI chr 1:209,453,229...209,457,085
Ensembl chr 1:209,453,229...209,457,085

G

fibroblast growth factor 6

decreases expression

ISO

Folic Acid results in decreased expression of FGF6 mRNA

NCBI chr 4:161,541,089...161,549,624
Ensembl chr 4:161,541,089...161,553,521

G

fibroblast growth factor 8

multiple interactions
increases expression

ISO

Folic Acid inhibits the reaction [[GLI3 gene mutant form co-treated with ochratoxin A] results in increased expression of FGF8 mRNA]
Folic Acid results in increased expression of FGF8 mRNA

PMID:17688467 PMID:21867686 PMID:25629700

NCBI chr 1:254,533,504...254,539,605
Ensembl chr 1:254,533,504...254,539,605

G

Fibroblast growth factor receptor 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of FGFR1 gene
Folic Acid results in decreased expression of FGFR1 mRNA

PMID:20938992 PMID:21867686

NCBI chr16:73,194,631...73,249,855
Ensembl chr16:73,194,631...73,249,855

G

FGFR1 oncogene partner 2

decreases expression

ISO

Folic Acid results in decreased expression of FGFR1OP2 mRNA

NCBI chr 4:181,222,298...181,243,318
Ensembl chr 4:181,222,323...181,243,322

G

fibrinogen gamma chain

multiple interactions
increases expression

ISO

icariin inhibits the reaction [Folic Acid results in increased expression of FGG protein]

NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:170,652,234...170,661,170

G

fibrinogen-like 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of FGL1 mRNA

NCBI chr16:57,824,127...57,854,413
Ensembl chr16:57,824,200...57,854,429

G

fibrinogen-like 2

decreases expression

ISO

Folic Acid results in decreased expression of FGL2 mRNA

NCBI chr 4:14,602,762...14,608,405
Ensembl chr 4:14,602,771...14,608,405

G

fumarate hydratase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FH1 mRNA

NCBI chr13:90,056,565...90,082,450
Ensembl chr13:90,056,570...90,089,627

G

FH2 domain containing 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of FHDC1 gene

NCBI chr 2:172,088,987...172,127,838
Ensembl chr 2:172,089,010...172,125,956

G

FHF complex subunit HOOK interacting protein 1A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FHIP1A mRNA

NCBI chr 2:173,319,252...173,489,514
Ensembl chr 2:173,319,257...173,453,902

G

FHF complex subunit HOOK interacting protein 1B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FHIP1B mRNA

NCBI chr 1:169,137,866...169,160,305
Ensembl chr 1:169,122,654...169,160,252

G

FHF complex subunit HOOK interacting protein 2A

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of FHIP2A gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of FHIP2A mRNA]

PMID:20938992 PMID:22206623

NCBI chr 1:266,422,617...266,449,206
Ensembl chr 1:266,422,723...266,449,206

G

FHF complex subunit HOOK interacting protein 2B

increases expression
multiple interactions

ISO

Folic Acid results in increased expression of FHIP2B mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FHIP2B mRNA

PMID:22206623 PMID:25629700

NCBI chr15:52,066,341...52,084,296
Ensembl chr15:52,066,341...52,083,798

G

four and a half LIM domains 1

affects expression
multiple interactions

ISO

Folic Acid affects the expression of FHL1 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FHL1 mRNA

PMID:17320366 PMID:22206623

NCBI chr X:139,592,794...139,652,290
Ensembl chr X:139,592,604...139,652,282

G

four and a half LIM domains 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FHL2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FHL2 mRNA

PMID:20938992 PMID:22206623

NCBI chr 9:52,881,091...52,954,540
Ensembl chr 9:52,880,998...52,923,326

G

four and a half LIM domains 3

multiple interactions
decreases expression

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of FHL3 mRNA]
Folic Acid results in decreased expression of FHL3 mRNA

PMID:22206623 PMID:25629700

NCBI chr 5:142,238,634...142,246,011
Ensembl chr 5:142,235,109...142,246,034

G

formin homology 2 domain containing 1

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of FHOD1 mRNA]

NCBI chr19:50,116,415...50,135,868
Ensembl chr19:50,116,415...50,135,330

G

FGF1 intracellular binding protein

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FIBP mRNA

NCBI chr 1:212,197,216...212,201,732
Ensembl chr 1:212,197,416...212,201,731

G

FIG4 phosphoinositide 5-phosphatase

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FIG4 mRNA

NCBI chr20:46,183,225...46,306,686
Ensembl chr20:46,183,225...46,306,477

G

fidgetin-like 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FIGNL1 mRNA

NCBI chr14:90,573,090...90,595,342
Ensembl chr14:90,581,771...90,592,316

G

FLT3-interacting zinc finger 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FIZ1 mRNA

NCBI chr 1:77,856,901...77,864,562
Ensembl chr 1:77,851,451...77,864,563

G

FKBP prolyl isomerase 14

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of FKBP14 mRNA]

NCBI chr 4:85,035,840...85,051,917
Ensembl chr 4:85,037,145...85,051,808

G

FKBP prolyl isomerase 1A

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of FKBP1A mRNA
Folic Acid results in decreased expression of FKBP1A mRNA

PMID:22206623 PMID:25629700

NCBI chr 3:160,500,748...160,520,492
Ensembl chr 3:160,500,726...160,524,233

G

FKBP prolyl isomerase 1B

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FKBP1B mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FKBP1B mRNA

PMID:20938992 PMID:22206623

NCBI chr 6:33,551,583...33,570,055
Ensembl chr 6:33,558,517...33,568,129

G

FKBP prolyl isomerase 3

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FKBP3 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of FKBP3 gene

PMID:20938992 PMID:22206623

NCBI chr 6:88,850,137...88,862,542
Ensembl chr 6:88,843,879...88,863,447

G

FKBP prolyl isomerase 4

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of FKBP4 gene; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of FKBP4 mRNA]

PMID:20938992 PMID:22206623

NCBI chr 4:163,389,464...163,397,918
Ensembl chr 4:163,389,464...163,397,918

G

FKBP prolyl isomerase 5

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of FKBP5 mRNA

NCBI chr20:6,458,931...6,577,227
Ensembl chr20:6,458,940...6,543,118

G

FKBP prolyl isomerase family member 6

affects expression

ISO

Folic Acid affects the expression of FKBP6 mRNA

NCBI chr12:26,947,443...27,026,913
Ensembl chr12:26,947,384...27,026,913

G

FKBP prolyl isomerase 7

decreases expression

ISO

Folic Acid results in decreased expression of FKBP7 mRNA

NCBI chr 3:82,016,647...82,030,913
Ensembl chr 3:82,016,513...82,028,573

G

FKBP prolyl isomerase 8

increases expression

ISO

Folic Acid results in increased expression of FKBP8 mRNA

NCBI chr16:18,929,581...18,936,621
Ensembl chr16:18,929,582...18,936,543

G

FKBP prolyl isomerase 9

decreases expression
multiple interactions

ISO

Folic Acid results in decreased expression of FKBP9 mRNA
[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FKBP9 mRNA

PMID:22206623 PMID:25629700

NCBI chr 4:87,436,439...87,486,909
Ensembl chr 4:87,436,478...87,508,940

G

fukutin related protein

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FKRP mRNA

NCBI chr 1:86,607,769...86,615,045
Ensembl chr 1:86,595,180...86,627,257

G

fukutin

decreases expression

ISO

Folic Acid results in decreased expression of FKTN mRNA

NCBI chr 5:73,134,746...73,191,772
Ensembl chr 5:73,135,361...73,189,181

G

flavin adenine dinucleotide synthetase 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FLAD1 mRNA

NCBI chr 2:177,117,183...177,126,650
Ensembl chr 2:177,117,655...177,126,650

G

folliculin

decreases expression

ISO

Folic Acid results in decreased expression of FLCN mRNA

NCBI chr10:45,088,164...45,107,581
Ensembl chr10:45,088,167...45,107,309

G

filaggrin

increases expression

ISO

Folic Acid results in increased expression of FLG mRNA

PMID:21867686 PMID:25629700

NCBI chr 2:181,583,801...181,596,464
Ensembl chr 2:181,583,808...181,595,968

G

Fli-1 proto-oncogene, ETS transcription factor

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of FLI1; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of FLI1 gene; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FLI1 mRNA
Folic Acid results in decreased expression of FLI1 mRNA

PMID:20938992 PMID:25629700

NCBI chr 8:39,089,526...39,209,511
Ensembl chr 8:39,089,533...39,208,557

G

FLII, actin remodeling protein

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FLII mRNA
Folic Acid results in decreased expression of FLII mRNA

PMID:22206623 PMID:25629700

NCBI chr10:45,893,566...45,907,547
Ensembl chr10:45,893,572...45,907,491

G

filamin A

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of FLNA mRNA

NCBI chr X:157,159,051...157,185,559
Ensembl chr X:157,159,051...157,182,343

G

filamin B

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of FLNB gene

NCBI chr15:19,392,212...19,525,278
Ensembl chr15:19,392,216...19,525,209

G

filamin C

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FLNC mRNA

NCBI chr 4:58,999,445...59,027,240
Ensembl chr 4:58,999,547...59,027,240

G

flotillin 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FLOT1 mRNA

NCBI chr20:2,922,662...2,932,906
Ensembl chr20:2,922,655...2,932,771

G

flotillin 2

multiple interactions
decreases expression
increases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of FLOT2 mRNA
Folic Acid results in decreased expression of FLOT2 mRNA
Folic Acid results in increased expression of FLOT2 mRNA

PMID:21867686 PMID:22206623 PMID:25629700

NCBI chr10:63,424,084...63,445,811
Ensembl chr10:63,423,806...63,445,810

G

fibronectin leucine rich transmembrane protein 1

decreases expression

ISO

Folic Acid results in decreased expression of FLRT1 mRNA

NCBI chr 1:213,704,983...213,782,958
Ensembl chr 1:213,704,038...213,782,981

G

fibronectin leucine rich transmembrane protein 2

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of FLRT2 gene
Folic Acid results in decreased expression of FLRT2 mRNA

PMID:20938992 PMID:25629700

NCBI chr 6:120,507,998...120,603,133
Ensembl chr 6:120,507,689...120,609,004

G

fibronectin leucine rich transmembrane protein 3

decreases expression

ISO

Folic Acid results in decreased expression of FLRT3 mRNA

NCBI chr 3:148,448,115...148,461,458
Ensembl chr 3:148,439,354...148,461,650

G

Fms related receptor tyrosine kinase 1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of FLT1 gene
Folic Acid results in decreased expression of FLT1 mRNA

PMID:20938992 PMID:25629700

NCBI chr12:12,333,050...12,504,750
Ensembl chr12:12,333,430...12,504,750

G

Fms related receptor tyrosine kinase 3 ligand

multiple interactions
increases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of FLT3L mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FLT3L mRNA
Folic Acid results in increased expression of FLT3L mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr 1:104,751,518...104,756,925
Ensembl chr 1:104,749,983...104,757,038

G

FLVCR choline and putative heme transporter 2

decreases expression

ISO

Folic Acid results in decreased expression of FLVCR2 mRNA

NCBI chr 6:111,139,352...111,203,345
Ensembl chr 6:111,139,295...111,203,345

G

FLYWCH-type zinc finger 1

decreases expression

ISO

Folic Acid results in decreased expression of FLYWCH1 mRNA

NCBI chr10:13,279,232...13,298,955
Ensembl chr10:13,279,232...13,298,925

G

FLYWCH family member 2

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FLYWCH2 mRNA

NCBI chr10:13,303,346...13,311,677
Ensembl chr10:13,303,321...13,311,657

G

formation of mitochondrial complex V assembly factor 1

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FMC1 mRNA

NCBI chr 4:68,241,009...68,249,045
Ensembl chr 4:68,241,009...68,268,534

G

formin 1

increases expression

ISO

Folic Acid results in increased expression of FMN1 mRNA

NCBI chr 3:120,555,445...120,939,978
Ensembl chr 3:120,555,431...120,933,124

G

formin 2

multiple interactions
increases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of FMN2 gene
Folic Acid results in increased expression of FMN2 mRNA

PMID:20938992 PMID:25629700

NCBI chr13:88,986,863...89,303,789
Ensembl chr13:88,986,842...89,303,789

G

formin-like 2

decreases expression

ISO

Folic Acid results in decreased expression of FMNL2 mRNA

NCBI chr 3:57,758,236...58,033,832
Ensembl chr 3:57,758,191...58,033,831

G

flavin containing dimethylaniline monoxygenase 1

decreases expression

ISO

Folic Acid results in decreased expression of FMO1 mRNA

NCBI chr13:77,715,405...77,747,666
Ensembl chr13:77,715,402...77,747,874

G

flavin containing dimethylaniline monoxygenase 2

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FMO2 mRNA

NCBI chr13:77,755,131...77,777,597
Ensembl chr13:77,757,629...77,777,534

G

flavin containing dimethylaniline monoxygenase 3

decreases expression

ISO

Folic Acid results in decreased expression of FMO3 mRNA

NCBI chr13:77,838,899...77,868,869
Ensembl chr13:77,842,602...77,861,256

G

flavin containing dimethylaniline monoxygenase 4

increases expression

ISO

Folic Acid results in increased expression of FMO4 mRNA

NCBI chr13:77,687,909...77,706,100
Ensembl chr13:77,687,909...77,706,100

G

flavin containing dimethylaniline monoxygenase 5

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of FMO5 mRNA]

NCBI chr 2:187,885,741...187,938,468
Ensembl chr 2:187,910,964...187,938,464

G

fragile X messenger ribonucleoprotein 1

decreases expression
increases expression

ISO

Folic Acid results in decreased expression of FMR1 mRNA
Folic Acid results in decreased expression of FMR1 protein
Folic Acid results in increased expression of FMR1 mRNA

PMID:21867686 PMID:25629700 PMID:26547318

NCBI chr X:152,284,857...152,322,686
Ensembl chr X:152,284,841...152,322,675

G

FMR1 neighbor

affects expression

ISO

Folic Acid affects the expression of FMR1NB mRNA

NCBI chr X:152,354,238...152,377,051
Ensembl chr X:152,354,238...152,377,051

G

fibronectin 1

increases expression
multiple interactions

ISO
EXP

Folic Acid results in increased expression of FN1 mRNA; Folic Acid results in increased expression of FN1 protein
[Methionine co-treated with Betaine co-treated with Choline co-treated with Folic Acid] inhibits the reaction [Carbon Tetrachloride results in increased expression of FN1 mRNA]
6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride inhibits the reaction [Folic Acid results in increased expression of FN1 protein]; 6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride promotes the reaction [pyrazolanthrone inhibits the reaction [Folic Acid results in increased expression of FN1 protein]]; celastrol inhibits the reaction [Folic Acid results in increased expression of FN1 protein]; Decitabine inhibits the reaction [Folic Acid results in increased expression of FN1 mRNA]; Metformin inhibits the reaction [Folic Acid results in increased expression of FN1 mRNA]; Metformin inhibits the reaction [Folic Acid results in increased expression of FN1 protein]; pyrazolanthrone inhibits the reaction [Folic Acid results in increased expression of FN1 protein]; SR 144528 inhibits the reaction [celastrol inhibits the reaction [Folic Acid results in increased expression of FN1 protein]]; trichostatin A inhibits the reaction [Folic Acid results in increased expression of FN1 mRNA]
Folic Acid inhibits the reaction [TGFB1 protein results in increased expression of FN1 mRNA]; Folic Acid inhibits the reaction [TGFB1 protein results in increased expression of FN1 protein]

PMID:29380373 PMID:29789558 PMID:31447676 PMID:34619300 PMID:36354958 More...

NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137

G

formin binding protein 1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of FNBP1 gene

NCBI chr 3:34,706,814...34,826,770
Ensembl chr 3:34,706,814...34,822,117

G

formin binding protein 4

decreases expression

ISO

Folic Acid results in decreased expression of FNBP4 mRNA

NCBI chr 3:97,188,852...97,218,916
Ensembl chr 3:97,188,884...97,219,435

G

fibronectin type III domain containing 3a

decreases expression

ISO

Folic Acid results in decreased expression of FNDC3A mRNA

NCBI chr15:54,099,510...54,276,963
Ensembl chr15:54,099,510...54,276,407

G

fibronectin type III domain containing 3B

multiple interactions
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FNDC3B mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of FNDC3B; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of FNDC3B gene
Folic Acid results in decreased expression of FNDC3B mRNA

PMID:20938992 PMID:22206623 PMID:25629700

NCBI chr 2:112,240,108...112,546,113
Ensembl chr 2:112,243,202...112,546,306

G

fibronectin type III domain containing 5

multiple interactions

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FNDC5 mRNA

NCBI chr 5:146,765,951...146,775,611
Ensembl chr 5:146,751,416...146,778,540

G

fibronectin type III domain containing 8

increases expression

ISO

Folic Acid results in increased expression of FNDC8 mRNA

NCBI chr10:68,323,500...68,331,638
Ensembl chr10:68,323,497...68,331,639

G

fibronectin type III domain containing 9

decreases expression

ISO

Folic Acid results in decreased expression of FNDC9 mRNA

NCBI chr10:31,166,051...31,170,964
Ensembl chr10:31,154,346...31,179,698

G

folliculin interacting protein 1

multiple interactions

ISO

Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of FNIP1 mRNA]

NCBI chr10:39,068,432...39,151,552
Ensembl chr10:39,068,445...39,151,552

G

folliculin interacting protein 2

decreases expression

ISO

Folic Acid results in decreased expression of FNIP2 mRNA

NCBI chr 2:166,894,726...167,006,490
Ensembl chr 2:166,897,075...167,006,055

G

farnesyltransferase, CAAX box, subunit alpha

decreases expression

ISO

Folic Acid results in decreased expression of FNTA mRNA

NCBI chr16:72,767,864...72,786,193
Ensembl chr16:72,767,627...72,788,229

G

farnesyltransferase, CAAX box, subunit beta

decreases expression

ISO

Folic Acid results in decreased expression of FNTB mRNA

NCBI chr 6:101,269,657...101,352,716
Ensembl chr 6:101,269,671...101,352,716

G

folate hydrolase 1

decreases expression

ISO

Folic Acid results in decreased expression of FOLH1 mRNA

NCBI chr 1:149,828,286...149,914,313
Ensembl chr 1:149,840,760...149,914,035

G

folate receptor alpha

affects expression
decreases methylation
multiple interactions
affects binding
increases transport
decreases abundance
decreases expression
increases uptake
affects abundance

ISO
EXP

Folic Acid affects the expression of FOLR1 mRNA
Folic Acid results in decreased methylation of FOLR1 promoter
Folic Acid inhibits the reaction [FOLR1 protein results in increased susceptibility to N-((5-((2-amino-4-oxo-4,7-dihydro-3H-pyrrolo(2,3-d)pyrimidin-6-yl)propyl)thiophen-2-yl)carbonyl)glutamic acid]; FOLR1 protein affects the reaction [Folic Acid results in increased expression of CADM1 mRNA]; FOLR1 protein affects the reaction [Folic Acid results in increased expression of CADM1 protein]; FOLR1 protein affects the reaction [Folic Acid results in increased expression of CDKN1A protein]; FOLR1 protein affects the reaction [Folic Acid results in increased expression of CDKN1B protein]; FOLR1 protein affects the reaction [Folic Acid results in increased expression of TP53 protein]; FOLR1 protein affects the reaction [Folic Acid results in increased phosphorylation of MAPK1 protein]; FOLR1 protein affects the reaction [Folic Acid results in increased phosphorylation of MAPK3 protein]; FOLR1 protein affects the reaction [Folic Acid results in increased phosphorylation of SRC protein]; FOLR1 protein affects the reaction [Folic Acid results in increased phosphorylation of STAT3 protein]; N-((5-((2-amino-4-oxo-4,7-dihydro-3H-pyrrolo(2,3-d)pyrimidin-6-yl)propyl)thiophen-2-yl)carbonyl)glutamic acid inhibits the reaction [Folic Acid binds to FOLR1 protein]
FOLR1 protein results in increased transport of Folic Acid
FOLR1 gene mutant form results in decreased abundance of Folic Acid
Folic Acid results in decreased expression of FOLR1 protein
RFC1 protein mutant form promotes the reaction [FOLR1 protein mutant form results in decreased abundance of Folic Acid]
FOLR1 protein results in increased uptake of Folic Acid
FOLR1 protein affects the abundance of Folic Acid
Folic Acid deficiency results in decreased expression of FOLR1 mRNA; Folic Acid results in decreased expression of FOLR1 mRNA

PMID:14581169 PMID:15705887 PMID:17311948 PMID:17482424 PMID:17616776 More...

NCBI chr 1:165,631,462...165,650,430
Ensembl chr 1:165,631,462...165,642,669

G

folate receptor beta

multiple interactions
affects binding
decreases expression

ISO

Folic Acid inhibits the reaction [FOLR2 protein results in increased susceptibility to lometrexol]; Folic Acid inhibits the reaction [FOLR2 protein results in increased susceptibility to N-((5-((2-amino-4-oxo-4,7-dihydro-3H-pyrrolo(2,3-d)pyrimidin-6-yl)propyl)thiophen-2-yl)carbonyl)glutamic acid]; N-((5-((2-amino-4-oxo-4,7-dihydro-3H-pyrrolo(2,3-d)pyrimidin-6-yl)propyl)thiophen-2-yl)carbonyl)glutamic acid inhibits the reaction [Folic Acid binds to FOLR2 protein]
Folic Acid affects the reaction [FOLR2 gene mutant form results in increased susceptibility to sodium arsenate]; Folic Acid deficiency promotes the reaction [FOLR2 gene mutant form results in increased susceptibility to Arsenicals]; Folic Acid promotes the reaction [FOLR2 mutant form results in increased susceptibility to Valproic Acid]
Folic Acid results in decreased expression of FOLR2 mRNA

PMID:11749123 PMID:14745917 PMID:15694460 PMID:16740727 PMID:17616776 More...

NCBI chr 1:165,612,047...165,630,382
Ensembl chr 1:165,612,063...165,617,731

G

Fos proto-oncogene, AP-1 transcription factor subunit

multiple interactions
increases expression
decreases expression

ISO

[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FOS mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of FOS; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of FOS gene; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FOS mRNA
Folic Acid deficiency results in increased expression of FOS mRNA; Folic Acid results in increased expression of FOS mRNA
Folic Acid results in decreased expression of FOS mRNA

PMID:2566606 PMID:20938992 PMID:22206623 PMID:25629700 PMID:28752528

NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598

G

FosB proto-oncogene, AP-1 transcription factor subunit

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of FOSB gene
Folic Acid results in decreased expression of FOSB mRNA
[Folic Acid deficiency co-treated with Methotrexate] results in increased expression of FOSB mRNA

PMID:20938992 PMID:24657277 PMID:25629700

NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:88,082,127...88,089,477

G

FOS like 1, AP-1 transcription factor subunit

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of FOSL1; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of FOSL1 gene; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FOSL1 mRNA

NCBI chr 1:212,183,885...212,192,391
Ensembl chr 1:212,183,833...212,192,391

G

forkhead box A1

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of FOXA1 gene
Folic Acid results in decreased expression of FOXA1 mRNA

PMID:20938992 PMID:25629700

NCBI chr 6:80,838,380...80,871,195
Ensembl chr 6:80,800,960...80,871,191

G

forkhead box A2

multiple interactions
decreases expression

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of FOXA2 gene
Folic Acid results in decreased expression of FOXA2 mRNA

PMID:20938992 PMID:25629700

NCBI chr 3:155,923,305...155,927,508
Ensembl chr 3:155,923,307...155,928,757

G

forkhead box B1

multiple interactions

ISO

[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of FOXB1 gene