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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:substituted spermine
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Accession:CHEBI:26735 term browser browse the term



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N(1),N(12)-diethylspermine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sat1 spermidine/spermine N1-acetyl transferase 1 multiple interactions
increases expression
ISO [N(1), N(12)-diethylspermine co-treated with Fluorouracil] results in increased activity of SAT1 protein; [N(1), N(12)-diethylspermine co-treated with stallimycin] results in increased activity of SAT1 protein; stallimycin promotes the reaction [N(1), N(12)-diethylspermine results in increased expression of SAT1 protein] CTD PMID:21814787 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    role 19844
      chemical role 19473
        antioxidant 16145
          spermine 69
            substituted spermine 1
              DOSPA trifluoroacetate 0
              N(1),N(12)-diethylspermine 1
              acetylspermine + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    main group molecular entity 19811
                      s-block molecular entity 19647
                        hydrogen molecular entity 19628
                          hydrides 19139
                            inorganic hydride 18156
                              pnictogen hydride 18146
                                nitrogen hydride 18059
                                  azane 17866
                                    ammonia 17865
                                      organic amino compound 17865
                                        polyamine 9025
                                          tetramine 188
                                            spermine 69
                                              substituted spermine 1
                                                DOSPA trifluoroacetate 0
                                                N(1),N(12)-diethylspermine 1
                                                acetylspermine + 0
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