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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:amiodarone
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Accession:CHEBI:2663 term browser browse the term
Definition:A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
Synonyms:exact_synonym: (2-butyl-1-benzofuran-3-yl){4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl}methanone
 related_synonym: 2-Butyl-3-(3,5-diiodo-4-(2-diethylaminoethoxy)benzoyl)benzofuran;   2-Butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl ketone;   2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuran;   Formula=C25H29I2NO3;   InChI=1S/C25H29I2NO3/c1-4-7-11-22-23(18-10-8-9-12-21(18)31-22)24(29)17-15-19(26)25(20(27)16-17)30-14-13-28(5-2)6-3/h8-10,12,15-16H,4-7,11,13-14H2,1-3H3;   InChIKey=IYIKLHRQXLHMJQ-UHFFFAOYSA-N;   SMILES=CCCCc1oc2ccccc2c1C(=O)c1cc(I)c(OCCN(CC)CC)c(I)c1;   amiodarona;   amiodaronum
 xref: Beilstein:1271711;   CAS:1951-25-3;   DrugBank:DB01118;   Drug_Central:176;   HMDB:HMDB0015250;   KEGG:C06823;   KEGG:D02910;   LINCS:LSM-2379
 xref_mesh: MESH:D000638
 xref: PMID:10188629;   PMID:16479044;   PMID:18368867;   Patent:CA2826272;   Patent:TW201400111;   Wikipedia:Amiodarone



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amiodarone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AADAT aminoadipate aminotransferase affects expression ISO Amiodarone affects the expression of AADAT mRNA CTD PMID:18355885 NCBI chr 4:170,060,222...170,094,292
Ensembl chr 4:170,060,222...170,091,699
JBrowse link
G ABCA1 ATP binding cassette subfamily A member 1 decreases expression EXP Amiodarone results in decreased expression of ABCA1 mRNA CTD PMID:29248575 NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155
JBrowse link
G ABCA2 ATP binding cassette subfamily A member 2 increases expression EXP Amiodarone results in increased expression of ABCA2 mRNA CTD PMID:19774075 NCBI chr 9:137,007,234...137,028,922
Ensembl chr 9:137,007,234...137,028,915
JBrowse link
G ABCB1 ATP binding cassette subfamily B member 1 multiple interactions
affects expression
affects response to substance
decreases activity
EXP
ISO
Amiodarone inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; Amiodarone inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]; Amiodarone inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]
Amiodarone affects the expression of ABCB1 mRNA; Amiodarone affects the expression of ABCB1A mRNA
Amiodarone inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]
ABCB1A protein affects the susceptibility to Amiodarone
Amiodarone results in decreased activity of ABCB1 protein
CTD PMID:11231118 PMID:12235267 PMID:15502009 PMID:18355885 PMID:19483382 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ABCB11 ATP binding cassette subfamily B member 11 multiple interactions
decreases expression
decreases activity
EXP
ISO
Amiodarone inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Amiodarone results in decreased expression of ABCB11 mRNA
Amiodarone results in decreased activity of ABCB11 protein
CTD PMID:20829430 PMID:24014644 PMID:27765674 NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324
JBrowse link
G ABCB4 ATP binding cassette subfamily B member 4 increases expression
decreases expression
ISO Amiodarone results in increased expression of ABCB4 mRNA
Amiodarone results in decreased expression of ABCB4 mRNA
CTD PMID:24489787 PMID:27765674 NCBI chr 7:87,365,896...87,476,027
Ensembl chr 7:87,401,696...87,480,435
JBrowse link
G ABCC11 ATP binding cassette subfamily C member 11 increases expression EXP Amiodarone results in increased expression of ABCC11 mRNA CTD PMID:19774075 NCBI chr16:48,164,819...48,247,539
Ensembl chr16:48,165,773...48,247,568
JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 increases expression ISO Amiodarone results in increased expression of ABCC2 mRNA CTD PMID:27765674 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594
JBrowse link
G ABCC3 ATP binding cassette subfamily C member 3 increases expression
decreases expression
ISO Amiodarone results in increased expression of ABCC3 mRNA
Amiodarone results in decreased expression of ABCC3 mRNA
CTD PMID:24489787 PMID:27765674 NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253
JBrowse link
G ABCC4 ATP binding cassette subfamily C member 4 (PEL blood group) decreases expression ISO Amiodarone results in decreased expression of ABCC4 mRNA CTD PMID:27765674 NCBI chr13:95,019,835...95,301,451
Ensembl chr13:95,019,835...95,301,475
JBrowse link
G ABCC6 ATP binding cassette subfamily C member 6 affects expression ISO Amiodarone affects the expression of ABCC6 mRNA CTD PMID:19483382 NCBI chr16:16,149,565...16,223,494
Ensembl chr16:16,149,565...16,223,522
JBrowse link
G ABCD3 ATP binding cassette subfamily D member 3 increases expression ISO Amiodarone results in increased expression of ABCD3 mRNA CTD PMID:24489787 NCBI chr 1:94,385,131...94,518,663
Ensembl chr 1:94,418,389...94,518,666
JBrowse link
G ABCD4 ATP binding cassette subfamily D member 4 increases expression ISO Amiodarone results in increased expression of ABCD4 mRNA CTD PMID:24489787 NCBI chr14:74,285,269...74,302,934
Ensembl chr14:74,285,269...74,303,055
JBrowse link
G ABCG5 ATP binding cassette subfamily G member 5 affects expression
increases expression
ISO Amiodarone affects the expression of ABCG5 mRNA
Amiodarone results in increased expression of ABCG5 mRNA
CTD PMID:19483382 PMID:27765674 NCBI chr 2:43,806,211...43,839,231
Ensembl chr 2:43,812,472...43,838,865
JBrowse link
G ABHD1 abhydrolase domain containing 1 affects expression ISO Amiodarone affects the expression of ABHD1 mRNA CTD PMID:19483382 NCBI chr 2:27,123,815...27,130,812
Ensembl chr 2:27,123,789...27,130,812
JBrowse link
G ABHD14B abhydrolase domain containing 14B affects expression ISO Amiodarone affects the expression of ABHD14B mRNA CTD PMID:19483382 NCBI chr 3:51,968,510...51,974,630
Ensembl chr 3:51,968,510...51,983,409
JBrowse link
G ABHD17A abhydrolase domain containing 17A, depalmitoylase affects expression ISO Amiodarone affects the expression of ABHD17A mRNA CTD PMID:19483382 NCBI chr19:1,876,810...1,885,496
Ensembl chr19:1,876,810...1,885,496
JBrowse link
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase increases expression EXP Amiodarone results in increased expression of ABL1 mRNA CTD PMID:19774075 NCBI chr 9:130,713,043...130,887,675
Ensembl chr 9:130,713,043...130,887,675
JBrowse link
G ACAA1 acetyl-CoA acyltransferase 1 increases expression ISO Amiodarone results in increased expression of ACAA1 mRNA CTD PMID:15265979 NCBI chr 3:38,122,715...38,137,127
Ensembl chr 3:38,103,129...38,137,242
JBrowse link
G ACACA acetyl-CoA carboxylase alpha affects expression
increases expression
ISO
EXP
Amiodarone affects the expression of ACACA mRNA
Amiodarone results in increased expression of ACACA mRNA
CTD PMID:19483382 PMID:19774075 NCBI chr17:37,084,992...37,406,836
Ensembl chr17:37,084,992...37,406,836
JBrowse link
G ACACB acetyl-CoA carboxylase beta increases expression ISO Amiodarone results in increased expression of ACACB mRNA CTD PMID:19224547 PMID:24489787 NCBI chr12:109,111,189...109,268,226
Ensembl chr12:109,116,587...109,268,226
JBrowse link
G ACAD10 acyl-CoA dehydrogenase family member 10 increases expression ISO Amiodarone results in increased expression of ACAD10 mRNA CTD PMID:24535564 NCBI chr12:111,686,053...111,757,099
Ensembl chr12:111,686,053...111,757,107
JBrowse link
G ACAD9 acyl-CoA dehydrogenase family member 9 increases expression ISO Amiodarone results in increased expression of ACAD9 mRNA CTD PMID:24489787 NCBI chr 3:128,879,620...128,913,114
Ensembl chr 3:128,879,596...128,924,003
JBrowse link
G ACADL acyl-CoA dehydrogenase long chain affects expression ISO Amiodarone affects the expression of ACADL mRNA CTD PMID:19483382 NCBI chr 2:210,187,923...210,225,447
Ensembl chr 2:210,187,126...210,225,447
JBrowse link
G ACADM acyl-CoA dehydrogenase medium chain increases expression ISO Amiodarone results in increased expression of ACADM mRNA CTD PMID:24489787 NCBI chr 1:75,724,709...75,763,679
Ensembl chr 1:75,724,431...75,787,575
JBrowse link
G ACAT1 acetyl-CoA acetyltransferase 1 increases expression ISO Amiodarone results in increased expression of ACAT1 mRNA CTD PMID:24489787 NCBI chr11:108,116,705...108,147,603
Ensembl chr11:108,116,695...108,148,957
JBrowse link
G ACAT2 acetyl-CoA acetyltransferase 2 increases expression ISO Amiodarone results in increased expression of ACAT2 mRNA CTD PMID:32084307 NCBI chr 6:159,762,045...159,779,112
Ensembl chr 6:159,762,045...159,779,112
JBrowse link
G ACER2 alkaline ceramidase 2 increases expression ISO Amiodarone results in increased expression of ACER2 mRNA CTD PMID:25580480 NCBI chr 9:19,409,009...19,452,505
Ensembl chr 9:19,409,009...19,452,505
JBrowse link
G ACLY ATP citrate lyase increases expression EXP
ISO
Amiodarone results in increased expression of ACLY mRNA CTD PMID:32084307 PMID:32535746 NCBI chr17:41,866,917...41,930,545
Ensembl chr17:41,866,917...41,930,542
JBrowse link
G ACO1 aconitase 1 affects expression ISO Amiodarone affects the expression of ACO1 mRNA CTD PMID:19483382 NCBI chr 9:32,384,643...32,454,769
Ensembl chr 9:32,384,603...32,454,769
JBrowse link
G ACO2 aconitase 2 affects expression ISO Amiodarone affects the expression of ACO2 mRNA CTD PMID:19483382 NCBI chr22:41,469,117...41,528,974
Ensembl chr22:41,447,830...41,529,273
JBrowse link
G ACOT1 acyl-CoA thioesterase 1 increases expression ISO Amiodarone results in increased expression of ACOT1 mRNA CTD PMID:24489787 PMID:24535564 PMID:30685923 PMID:32084307 NCBI chr14:73,490,933...73,543,796
Ensembl chr14:73,537,143...73,543,796
JBrowse link
G ACOT12 acyl-CoA thioesterase 12 affects expression
increases expression
ISO Amiodarone affects the expression of ACOT12 mRNA
Amiodarone results in increased expression of ACOT12 mRNA
CTD PMID:19483382 PMID:24489787 NCBI chr 5:81,308,609...81,394,134
Ensembl chr 5:81,329,996...81,394,179
JBrowse link
G ACOT2 acyl-CoA thioesterase 2 increases expression ISO Amiodarone results in increased expression of ACOT2 mRNA CTD PMID:24489787 PMID:24535564 PMID:30685923 NCBI chr14:73,567,620...73,575,658
Ensembl chr14:73,567,620...73,575,658
JBrowse link
G ACOT4 acyl-CoA thioesterase 4 affects expression ISO Amiodarone affects the expression of ACOT4 mRNA CTD PMID:19483382 NCBI chr14:73,591,873...73,595,766
Ensembl chr14:73,591,873...73,595,766
JBrowse link
G ACOT8 acyl-CoA thioesterase 8 increases expression EXP Amiodarone results in increased expression of ACOT8 mRNA CTD PMID:19774075 NCBI chr20:45,841,721...45,857,392
Ensembl chr20:45,841,721...45,857,405
JBrowse link
G ACOX1 acyl-CoA oxidase 1 increases expression ISO Amiodarone results in increased expression of ACOX1 mRNA CTD PMID:15265979 PMID:30685923 NCBI chr17:75,941,507...75,979,166
Ensembl chr17:75,941,507...75,979,177
JBrowse link
G ACOX2 acyl-CoA oxidase 2 increases expression ISO Amiodarone results in increased expression of ACOX2 mRNA CTD PMID:24489787 NCBI chr 3:58,505,136...58,537,190
Ensembl chr 3:58,505,136...58,537,283
JBrowse link
G ACSF3 acyl-CoA synthetase family member 3 increases expression EXP Amiodarone results in increased expression of ACSF3 mRNA CTD PMID:19774075 NCBI chr16:89,093,852...89,156,233
Ensembl chr16:89,088,375...89,164,121
JBrowse link
G ACSL3 acyl-CoA synthetase long chain family member 3 increases expression ISO Amiodarone results in increased expression of ACSL3 mRNA CTD PMID:32084307 NCBI chr 2:222,861,036...222,944,639
Ensembl chr 2:222,860,942...222,944,639
JBrowse link
G ACSS2 acyl-CoA synthetase short chain family member 2 increases expression ISO Amiodarone results in increased expression of ACSS2 mRNA CTD PMID:24535564 PMID:32084307 NCBI chr20:34,874,989...34,927,959
Ensembl chr20:34,872,146...34,927,962
JBrowse link
G ACTA2 actin alpha 2, smooth muscle multiple interactions
increases expression
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Amiodarone results in increased expression of ACTA2 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Amiodarone results in increased expression of ACTA2 protein]; SB 203580 inhibits the reaction [Amiodarone results in increased expression of ACTA2 mRNA]; SB 203580 inhibits the reaction [Amiodarone results in increased expression of ACTA2 protein]
Amiodarone results in increased expression of ACTA2 mRNA; Amiodarone results in increased expression of ACTA2 protein
CTD PMID:31071512 NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,934,822...88,991,339
JBrowse link
G ACTR3B actin related protein 3B increases expression EXP Amiodarone results in increased expression of ACTR3B mRNA CTD PMID:19774075 NCBI chr 7:152,759,752...152,855,378
Ensembl chr 7:152,759,749...152,855,378
JBrowse link
G ACVR1B activin A receptor type 1B increases expression EXP Amiodarone results in increased expression of ACVR1B mRNA CTD PMID:19774075 NCBI chr12:51,951,699...51,997,078
Ensembl chr12:51,951,699...51,997,078
JBrowse link
G ACYP1 acylphosphatase 1 increases expression EXP Amiodarone results in increased expression of ACYP1 mRNA CTD PMID:19774075 NCBI chr14:75,053,243...75,069,490
Ensembl chr14:75,053,237...75,069,483
JBrowse link
G ADA2 adenosine deaminase 2 increases expression EXP Amiodarone results in increased expression of ADA2 mRNA CTD PMID:19774075 NCBI chr22:17,178,790...17,221,848
Ensembl chr22:17,178,790...17,258,235
JBrowse link
G ADAM15 ADAM metallopeptidase domain 15 affects expression ISO Amiodarone affects the expression of ADAM15 mRNA CTD PMID:19483382 NCBI chr 1:155,051,316...155,062,775
Ensembl chr 1:155,050,566...155,062,775
JBrowse link
G ADD1 adducin 1 affects expression ISO Amiodarone affects the expression of ADD1 mRNA CTD PMID:19483382 NCBI chr 4:2,843,844...2,930,062
Ensembl chr 4:2,843,844...2,930,076
JBrowse link
G ADGRD1 adhesion G protein-coupled receptor D1 increases expression EXP Amiodarone results in increased expression of ADGRD1 mRNA CTD PMID:19774075 NCBI chr12:130,953,907...131,141,469
Ensembl chr12:130,953,907...131,141,469
JBrowse link
G ADGRF1 adhesion G protein-coupled receptor F1 decreases expression ISO Amiodarone results in decreased expression of ADGRF1 mRNA CTD PMID:24535564 NCBI chr 6:46,997,708...47,042,332
Ensembl chr 6:46,997,708...47,042,350
JBrowse link
G ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide affects expression ISO Amiodarone affects the expression of ADH4 mRNA CTD PMID:19483382 NCBI chr 4:99,123,658...99,144,297
Ensembl chr 4:99,123,657...99,157,792
JBrowse link
G ADM2 adrenomedullin 2 multiple interactions EXP ADM2 protein inhibits the reaction [Amiodarone results in decreased activity of CAT protein]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of and results in decreased phosphorylation of CTNNB1 protein]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 protein]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of CAT mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of GPX1 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 protein]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of SOD1 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of SOD2 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX protein]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 protein]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B protein]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 protein]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of TNF mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of TNF protein]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of TNF protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased activity of CAT protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of and results in decreased phosphorylation of CTNNB1 protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of CAT mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of GPX1 mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of SOD1 mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of SOD2 mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of TNF mRNA]] CTD PMID:34434487 NCBI chr22:50,481,543...50,486,437
Ensembl chr22:50,481,543...50,486,440
JBrowse link
G ADORA3 adenosine A3 receptor increases expression EXP Amiodarone results in increased expression of ADORA3 mRNA CTD PMID:19774075 NCBI chr 1:111,499,429...111,503,633
Ensembl chr 1:111,499,429...111,503,633
JBrowse link
G ADRA2A adrenoceptor alpha 2A increases expression EXP Amiodarone results in increased expression of ADRA2A mRNA CTD PMID:19774075 NCBI chr10:111,077,029...111,080,907
Ensembl chr10:111,077,029...111,080,907
JBrowse link
G ADRB1 adrenoceptor beta 1 decreases expression EXP Amiodarone results in decreased expression of ADRB1 protein CTD PMID:1653643 NCBI chr10:114,043,866...114,046,904
Ensembl chr10:114,043,866...114,046,904
JBrowse link
G ADRB2 adrenoceptor beta 2 decreases expression EXP Amiodarone results in decreased expression of ADRB2 protein CTD PMID:1653643 NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623
JBrowse link
G ADRB3 adrenoceptor beta 3 multiple interactions ISO Amiodarone inhibits the reaction [Triiodothyronine results in decreased expression of ADRB3 protein] CTD PMID:10217540 NCBI chr 8:37,962,990...37,966,599
Ensembl chr 8:37,962,990...37,966,599
JBrowse link
G ADTRP androgen dependent TFPI regulating protein affects expression ISO Amiodarone affects the expression of ADTRP mRNA CTD PMID:19483382 NCBI chr 6:11,713,523...11,778,803
Ensembl chr 6:11,712,054...11,807,046
JBrowse link
G AFM afamin affects expression ISO Amiodarone affects the expression of AFM mRNA CTD PMID:19483382 NCBI chr 4:73,481,745...73,504,001
Ensembl chr 4:73,481,745...73,504,001
JBrowse link
G AFP alpha fetoprotein increases expression ISO Amiodarone results in increased expression of AFP mRNA CTD PMID:24489787 NCBI chr 4:73,436,221...73,456,174
Ensembl chr 4:73,431,138...73,456,174
JBrowse link
G AGT angiotensinogen increases expression
affects expression
multiple interactions
EXP
ISO
Amiodarone results in increased expression of AGT mRNA; Amiodarone results in increased expression of AGT protein
Amiodarone affects the expression of AGT mRNA
[FOS protein co-treated with JUN protein] promotes the reaction [Amiodarone results in increased expression of AGT mRNA]; Dactinomycin inhibits the reaction [Amiodarone results in increased expression of AGT mRNA]
CTD PMID:17214612 PMID:19483382 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
JBrowse link
G AGTR1 angiotensin II receptor type 1 affects expression ISO Amiodarone affects the expression of AGTR1A mRNA CTD PMID:19483382 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008
JBrowse link
G AHNAK AHNAK nucleoprotein increases expression EXP Amiodarone results in increased expression of AHNAK mRNA CTD PMID:19774075 NCBI chr11:62,433,544...62,546,806
Ensembl chr11:62,433,542...62,556,235
JBrowse link
G AHR aryl hydrocarbon receptor affects expression EXP Amiodarone affects the expression of AHR mRNA CTD PMID:35641671 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152
JBrowse link
G AIFM1 apoptosis inducing factor mitochondria associated 1 increases expression ISO Amiodarone results in increased expression of AIFM1 mRNA CTD PMID:24489787 NCBI chr  X:130,129,362...130,165,841
Ensembl chr  X:130,124,666...130,165,879
JBrowse link
G AK4 adenylate kinase 4 increases expression ISO Amiodarone results in increased expression of AK4 protein CTD PMID:16538043 NCBI chr 1:65,147,552...65,232,145
Ensembl chr 1:65,147,549...65,232,145
JBrowse link
G AKR1A1 aldo-keto reductase family 1 member A1 affects expression ISO Amiodarone affects the expression of AKR1A1 mRNA CTD PMID:19483382 NCBI chr 1:45,550,826...45,570,049
Ensembl chr 1:45,550,543...45,570,049
JBrowse link
G AKR1C1 aldo-keto reductase family 1 member C1 increases expression EXP Amiodarone results in increased expression of AKR1C1 mRNA CTD PMID:21163907 NCBI chr10:4,963,415...4,983,283
Ensembl chr10:4,963,253...4,983,283
JBrowse link
G AKR7A2 aldo-keto reductase family 7 member A2 affects expression ISO Amiodarone affects the expression of AKR7A2 mRNA CTD PMID:19483382 NCBI chr 1:19,302,708...19,312,146
Ensembl chr 1:19,301,991...19,312,144
JBrowse link
G AKR7A3 aldo-keto reductase family 7 member A3 affects expression ISO Amiodarone affects the expression of AKR7A3 mRNA CTD PMID:19483382 NCBI chr 1:19,274,229...19,288,770
Ensembl chr 1:19,282,573...19,288,770
JBrowse link
G AKT1 AKT serine/threonine kinase 1 decreases phosphorylation EXP
ISO
Amiodarone results in decreased phosphorylation of AKT1 protein CTD PMID:23912912 PMID:26515726 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759
JBrowse link
G ALAS1 5'-aminolevulinate synthase 1 increases expression EXP Amiodarone results in increased expression of ALAS1 mRNA CTD PMID:19774075 NCBI chr 3:52,198,083...52,214,327
Ensembl chr 3:52,198,086...52,214,327
JBrowse link
G ALAS2 5'-aminolevulinate synthase 2 decreases expression ISO Amiodarone results in decreased expression of ALAS2 mRNA CTD PMID:24535564 NCBI chr  X:55,009,055...55,030,977
Ensembl chr  X:55,009,055...55,030,977
JBrowse link
G ALB albumin increases expression EXP Amiodarone results in increased expression of ALB mRNA CTD PMID:19774075 PMID:36586010 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
JBrowse link
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 affects expression ISO Amiodarone affects the expression of ALDH1A1 mRNA CTD PMID:18355885 PMID:19483382 NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442
JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member affects expression ISO Amiodarone affects the expression of ALDH2 mRNA CTD PMID:19483382 NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532
JBrowse link
G ALDH3A2 aldehyde dehydrogenase 3 family member A2 increases expression ISO Amiodarone results in increased expression of ALDH3A2 mRNA CTD PMID:24535564 NCBI chr17:19,648,136...19,677,596
Ensembl chr17:19,648,136...19,685,760
JBrowse link
G ALDH6A1 aldehyde dehydrogenase 6 family member A1 increases expression ISO Amiodarone results in increased expression of ALDH6A1 mRNA CTD PMID:17991464 NCBI chr14:74,056,847...74,084,453
Ensembl chr14:74,056,847...74,084,492
JBrowse link
G ALG12 ALG12 alpha-1,6-mannosyltransferase increases expression EXP Amiodarone results in increased expression of ALG12 mRNA CTD PMID:19774075 NCBI chr22:49,859,311...49,918,438
Ensembl chr22:49,900,229...49,918,438
JBrowse link
G ALG2 ALG2 alpha-1,3/1,6-mannosyltransferase increases expression EXP Amiodarone results in increased expression of ALG2 mRNA CTD PMID:19774075 NCBI chr 9:99,216,425...99,221,942
Ensembl chr 9:99,216,425...99,221,942
JBrowse link
G ALK ALK receptor tyrosine kinase increases expression EXP Amiodarone results in increased expression of ALK mRNA CTD PMID:19774075 NCBI chr 2:29,192,774...29,921,586
Ensembl chr 2:29,192,774...29,921,586
JBrowse link
G ALKAL1 ALK and LTK ligand 1 increases expression EXP Amiodarone results in increased expression of ALKAL1 mRNA CTD PMID:19774075 NCBI chr 8:52,534,037...52,565,430
Ensembl chr 8:52,534,037...52,565,430
JBrowse link
G ALKBH7 alkB homolog 7 affects expression ISO Amiodarone affects the expression of ALKBH7 mRNA CTD PMID:19483382 NCBI chr19:6,372,794...6,375,250
Ensembl chr19:6,372,794...6,375,250
JBrowse link
G AMIGO1 adhesion molecule with Ig like domain 1 increases expression EXP Amiodarone results in increased expression of AMIGO1 mRNA CTD PMID:19774075 NCBI chr 1:109,504,178...109,509,727
Ensembl chr 1:109,504,178...109,509,738
JBrowse link
G ANGPTL3 angiopoietin like 3 decreases expression EXP Amiodarone results in decreased expression of ANGPTL3 mRNA CTD PMID:27089845 NCBI chr 1:62,597,520...62,606,313
Ensembl chr 1:62,597,520...62,606,313
JBrowse link
G ANGPTL4 angiopoietin like 4 increases expression ISO Amiodarone results in increased expression of ANGPTL4 mRNA CTD PMID:24489787 NCBI chr19:8,364,155...8,374,370
Ensembl chr19:8,363,289...8,374,370
JBrowse link
G ANXA4 annexin A4 increases expression EXP Amiodarone results in increased expression of ANXA4 mRNA CTD PMID:19774075 NCBI chr 2:69,643,808...69,827,112
Ensembl chr 2:69,644,425...69,827,112
JBrowse link
G AOX3P aldehyde oxidase 3, pseudogene decreases expression ISO Amiodarone results in decreased expression of AOX3 mRNA CTD PMID:24535564 NCBI chr 2:200,695,723...200,738,781
Ensembl chr 2:200,678,233...200,732,539
JBrowse link
G AP1S1 adaptor related protein complex 1 subunit sigma 1 decreases expression
increases expression
EXP Amiodarone results in decreased expression of AP1S1 mRNA
Amiodarone results in increased expression of AP1S1 mRNA
CTD PMID:17175557 PMID:17567588 PMID:29248575 NCBI chr 7:101,154,476...101,161,276
Ensembl chr 7:101,154,456...101,161,596
JBrowse link
G AP2M1 adaptor related protein complex 2 subunit mu 1 affects expression ISO Amiodarone affects the expression of AP2M1 mRNA CTD PMID:19483382 NCBI chr 3:184,174,855...184,184,091
Ensembl chr 3:184,174,689...184,184,214
JBrowse link
G APCS amyloid P component, serum affects expression ISO Amiodarone affects the expression of APCS mRNA CTD PMID:19483382 NCBI chr 1:159,587,826...159,588,865
Ensembl chr 1:159,587,826...159,588,865
JBrowse link
G APOA4 apolipoprotein A4 affects expression ISO Amiodarone affects the expression of APOA4 mRNA CTD PMID:18355885 PMID:19483382 NCBI chr11:116,820,700...116,823,304
Ensembl chr11:116,820,700...116,823,304
JBrowse link
G APOA5 apolipoprotein A5 increases expression ISO Amiodarone results in increased expression of APOA5 mRNA CTD PMID:24489787 NCBI chr11:116,789,367...116,792,420
Ensembl chr11:116,789,367...116,792,420
JBrowse link
G APOB apolipoprotein B decreases expression EXP Amiodarone results in decreased expression of APOB mRNA CTD PMID:29248575 NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073
JBrowse link
G APOC2 apolipoprotein C2 increases expression ISO Amiodarone results in increased expression of APOC2 mRNA CTD PMID:24489787 NCBI chr19:44,946,051...44,949,565
Ensembl chr19:44,946,035...44,949,565
JBrowse link
G APOE apolipoprotein E decreases expression ISO Amiodarone results in decreased expression of APOE mRNA CTD PMID:17991464 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
JBrowse link
G APOH apolipoprotein H affects expression ISO Amiodarone affects the expression of APOH mRNA CTD PMID:19483382 NCBI chr17:66,212,033...66,229,415
Ensembl chr17:66,212,033...66,256,525
JBrowse link
G APOOL apolipoprotein O like affects expression ISO Amiodarone affects the expression of APOOL mRNA CTD PMID:19483382 NCBI chr  X:85,003,877...85,093,315
Ensembl chr  X:85,003,877...85,093,315
JBrowse link
G ARC activity regulated cytoskeleton associated protein increases expression EXP Amiodarone results in increased expression of ARC mRNA CTD PMID:19774075 NCBI chr 8:142,611,049...142,614,479
Ensembl chr 8:142,611,049...142,614,479
JBrowse link
G ARG1 arginase 1 affects expression ISO Amiodarone affects the expression of ARG1 mRNA CTD PMID:19483382 NCBI chr 6:131,573,226...131,584,329
Ensembl chr 6:131,470,832...131,584,332
JBrowse link
G ARHGAP15 Rho GTPase activating protein 15 increases expression EXP Amiodarone results in increased expression of ARHGAP15 mRNA CTD PMID:19774075 NCBI chr 2:143,129,419...143,768,352
Ensembl chr 2:143,091,362...143,768,352
JBrowse link
G ARHGAP35 Rho GTPase activating protein 35 increases expression EXP Amiodarone results in increased expression of ARHGAP35 mRNA CTD PMID:19774075 NCBI chr19:46,860,997...47,005,077
Ensembl chr19:46,860,997...47,005,077
JBrowse link
G ARHGAP4 Rho GTPase activating protein 4 increases expression EXP Amiodarone results in increased expression of ARHGAP4 mRNA CTD PMID:19774075 NCBI chr  X:153,907,378...153,926,264
Ensembl chr  X:153,907,367...153,934,999
JBrowse link
G ARHGAP45 Rho GTPase activating protein 45 increases expression EXP Amiodarone results in increased expression of ARHGAP45 mRNA CTD PMID:19774075 NCBI chr19:1,065,959...1,086,628
Ensembl chr19:1,065,923...1,086,628
JBrowse link
G ARHGAP9 Rho GTPase activating protein 9 increases expression EXP Amiodarone results in increased expression of ARHGAP9 mRNA CTD PMID:19774075 NCBI chr12:57,472,269...57,488,824
Ensembl chr12:57,472,264...57,488,814
JBrowse link
G ARHGEF10L Rho guanine nucleotide exchange factor 10 like increases expression EXP Amiodarone results in increased expression of ARHGEF10L mRNA CTD PMID:19774075 NCBI chr 1:17,513,435...17,697,875
Ensembl chr 1:17,539,698...17,697,874
JBrowse link
G ARHGEF7 Rho guanine nucleotide exchange factor 7 increases expression EXP Amiodarone results in increased expression of ARHGEF7 mRNA CTD PMID:19774075 NCBI chr13:111,114,619...111,305,734
Ensembl chr13:111,114,559...111,305,737
JBrowse link
G ARHGEF9 Cdc42 guanine nucleotide exchange factor 9 increases expression EXP Amiodarone results in increased expression of ARHGEF9 mRNA CTD PMID:19774075 NCBI chr  X:63,634,967...63,785,214
Ensembl chr  X:63,634,967...63,809,274
JBrowse link
G ARID5A AT-rich interaction domain 5A increases expression EXP Amiodarone results in increased expression of ARID5A mRNA CTD PMID:19774075 NCBI chr 2:96,536,752...96,552,638
Ensembl chr 2:96,536,743...96,552,638
JBrowse link
G ARL6IP1 ARL6 interacting reticulophagy regulator 1 affects expression ISO Amiodarone affects the expression of ARL6IP1 mRNA CTD PMID:19483382 NCBI chr16:18,791,667...18,801,549
Ensembl chr16:18,791,609...18,801,572
JBrowse link
G ARMC9 armadillo repeat containing 9 increases expression EXP Amiodarone results in increased expression of ARMC9 mRNA CTD PMID:19774075 NCBI chr 2:231,198,631...231,376,848
Ensembl chr 2:231,198,546...231,376,848
JBrowse link
G ARPC4 actin related protein 2/3 complex subunit 4 increases expression EXP Amiodarone results in increased expression of ARPC4 mRNA CTD PMID:19774075 NCBI chr 3:9,792,518...9,807,101
Ensembl chr 3:9,792,495...9,807,101
JBrowse link
G ASAH1 N-acylsphingosine amidohydrolase 1 increases expression ISO
EXP
Amiodarone results in increased expression of ASAH1 mRNA CTD PMID:15342952 PMID:17567588 PMID:19224547 NCBI chr 8:18,055,992...18,084,961
Ensembl chr 8:18,055,992...18,084,998
JBrowse link
G ASB7 ankyrin repeat and SOCS box containing 7 increases expression EXP Amiodarone results in increased expression of ASB7 mRNA CTD PMID:19774075 NCBI chr15:100,602,589...100,651,701
Ensembl chr15:100,602,589...100,651,701
JBrowse link
G ASGR2 asialoglycoprotein receptor 2 affects expression ISO Amiodarone affects the expression of ASGR2 mRNA CTD PMID:19483382 NCBI chr17:7,101,322...7,115,146
Ensembl chr17:7,101,322...7,115,700
JBrowse link
G ASNS asparagine synthetase (glutamine-hydrolyzing) increases expression EXP Amiodarone results in increased expression of ASNS mRNA CTD PMID:17175557 PMID:17567588 PMID:36586010 NCBI chr 7:97,851,677...97,928,441
Ensembl chr 7:97,851,677...97,872,542
JBrowse link
G ATF3 activating transcription factor 3 increases expression
multiple interactions
EXP
ISO
Amiodarone results in increased expression of ATF3 mRNA
1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone promotes the reaction [Amiodarone results in increased expression of ATF3 mRNA]
CTD PMID:19774075 PMID:34259586 PMID:36586010 NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777
JBrowse link
G ATF4 activating transcription factor 4 increases expression
decreases expression
multiple interactions
EXP
ISO
Amiodarone results in increased expression of ATF4 mRNA; Amiodarone results in increased expression of ATF4 protein
Amiodarone results in decreased expression of ATF4 mRNA
1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of ATF4 mRNA]
CTD PMID:21292685 PMID:28962527 PMID:34259586 PMID:35641671 PMID:36586010 NCBI chr22:39,520,559...39,522,686
Ensembl chr22:39,519,695...39,522,686
JBrowse link
G ATF5 activating transcription factor 5 affects expression ISO Amiodarone affects the expression of ATF5 mRNA CTD PMID:19483382 NCBI chr19:49,928,906...49,933,935
Ensembl chr19:49,928,702...49,933,935
JBrowse link
G ATF6 activating transcription factor 6 multiple interactions ISO Amiodarone results in increased expression of and affects the localization of ATF6 protein CTD PMID:28962527 NCBI chr 1:161,766,320...161,964,070
Ensembl chr 1:161,766,298...161,977,574
JBrowse link
G ATF6B activating transcription factor 6 beta increases expression EXP Amiodarone results in increased expression of ATF6B mRNA CTD PMID:19774075 NCBI chr 6:32,115,264...32,128,246
Ensembl chr 6:32,115,264...32,128,253
JBrowse link
G ATG5 autophagy related 5 affects response to substance EXP ATG5 protein affects the susceptibility to Amiodarone CTD PMID:32651653 NCBI chr 6:106,184,476...106,325,760
Ensembl chr 6:106,045,423...106,325,791
JBrowse link
G ATG7 autophagy related 7 increases expression
affects response to substance
multiple interactions
EXP Amiodarone results in increased expression of ATG7 protein
ATG7 protein affects the susceptibility to Amiodarone
ATG7 protein affects the reaction [Amiodarone results in increased cleavage of CASP3 protein]
CTD PMID:23912912 PMID:32651653 NCBI chr 3:11,272,397...11,576,353
Ensembl chr 3:11,272,309...11,557,665
JBrowse link
G ATOH1 atonal bHLH transcription factor 1 increases expression EXP Amiodarone results in increased expression of ATOH1 mRNA CTD PMID:19774075 NCBI chr 4:93,828,753...93,830,964
Ensembl chr 4:93,828,753...93,830,964
JBrowse link
G ATP11C ATPase phospholipid transporting 11C increases expression EXP Amiodarone results in increased expression of ATP11C mRNA CTD PMID:19774075 NCBI chr  X:139,726,348...139,936,903
Ensembl chr  X:139,726,346...139,945,276
JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 decreases expression ISO Amiodarone results in decreased expression of ATP1A1 protein CTD PMID:8071999 NCBI chr 1:116,373,244...116,404,774
Ensembl chr 1:116,372,668...116,410,261
JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 decreases expression ISO Amiodarone results in decreased expression of ATP1A2 mRNA; Amiodarone results in decreased expression of ATP1A2 protein CTD PMID:7573397 PMID:8071999 PMID:12479229 NCBI chr 1:160,115,759...160,143,591
Ensembl chr 1:160,115,759...160,143,591
JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 decreases expression ISO Amiodarone results in decreased expression of ATP1B1 protein CTD PMID:8071999 NCBI chr 1:169,106,690...169,132,719
Ensembl chr 1:169,105,697...169,310,992
JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 decreases expression ISO Amiodarone results in decreased expression of ATP1B2 mRNA CTD PMID:8071999 NCBI chr17:7,646,627...7,657,770
Ensembl chr17:7,646,627...7,657,770
JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 decreases expression ISO Amiodarone results in decreased expression of ATP2A2 mRNA CTD PMID:17535870 NCBI chr12:110,280,616...110,351,093
Ensembl chr12:110,280,756...110,351,093
JBrowse link
G ATP5F1B ATP synthase F1 subunit beta increases expression ISO Amiodarone results in increased expression of ATP5F1B mRNA CTD PMID:17991464 NCBI chr12:56,638,175...56,645,984
Ensembl chr12:56,638,175...56,645,984
JBrowse link
G ATP5F1E ATP synthase F1 subunit epsilon affects expression ISO Amiodarone affects the expression of ATP5F1E mRNA CTD PMID:19483382 NCBI chr20:59,025,475...59,032,335
Ensembl chr20:59,025,475...59,032,345
JBrowse link
G ATP6AP2 ATPase H+ transporting accessory protein 2 affects expression ISO Amiodarone affects the expression of ATP6AP2 mRNA CTD PMID:19483382 NCBI chr  X:40,580,970...40,606,848
Ensembl chr  X:40,579,372...40,606,848
JBrowse link
G ATP6V1A ATPase H+ transporting V1 subunit A affects expression ISO Amiodarone affects the expression of ATP6V1A mRNA CTD PMID:19483382 NCBI chr 3:113,747,035...113,812,056
Ensembl chr 3:113,746,770...113,812,056
JBrowse link
G ATP6V1F ATPase H+ transporting V1 subunit F affects expression ISO Amiodarone affects the expression of ATP6V1F mRNA CTD PMID:19483382 NCBI chr 7:128,862,856...128,865,847
Ensembl chr 7:128,862,856...128,865,847
JBrowse link
G BAAT bile acid-CoA:amino acid N-acyltransferase affects expression ISO Amiodarone affects the expression of BAAT mRNA CTD PMID:19483382 NCBI chr 9:101,360,417...101,385,006
Ensembl chr 9:101,354,182...101,385,400
JBrowse link
G BAG1 BAG cochaperone 1 increases expression EXP Amiodarone results in increased expression of BAG1 mRNA CTD PMID:19774075 NCBI chr 9:33,252,471...33,264,708
Ensembl chr 9:33,247,820...33,264,720
JBrowse link
G BAG3 BAG cochaperone 3 decreases expression ISO Amiodarone results in decreased expression of BAG3 mRNA CTD PMID:17991464 NCBI chr10:119,651,380...119,677,819
Ensembl chr10:119,651,380...119,677,819
JBrowse link
G BAIAP2L1 BAR/IMD domain containing adaptor protein 2 like 1 increases expression EXP Amiodarone results in increased expression of BAIAP2L1 mRNA CTD PMID:19774075 NCBI chr 7:98,291,650...98,401,090
Ensembl chr 7:98,291,650...98,401,090
JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression
multiple interactions
EXP Amiodarone results in increased expression of BAX mRNA; Amiodarone results in increased expression of BAX protein
ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX protein]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX protein]]
CTD PMID:12084619 PMID:34434487 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BBC3 BCL2 binding component 3 increases expression EXP Amiodarone results in increased expression of BBC3 mRNA CTD PMID:36586010 NCBI chr19:47,220,824...47,232,860
Ensembl chr19:47,220,822...47,232,766
JBrowse link
G BBOX1 gamma-butyrobetaine hydroxylase 1 increases expression EXP Amiodarone results in increased expression of BBOX1 mRNA CTD PMID:19774075 NCBI chr11:27,040,815...27,127,809
Ensembl chr11:27,040,725...27,127,809
JBrowse link
G BCKDHA branched chain keto acid dehydrogenase E1 subunit alpha increases expression ISO Amiodarone results in increased expression of BCKDHA protein CTD PMID:16538043 NCBI chr19:41,397,818...41,425,002
Ensembl chr19:41,397,808...41,425,002
JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression
multiple interactions
ISO
EXP
Amiodarone results in decreased expression of BCL2 protein
Amiodarone results in decreased expression of BCL2 mRNA; Amiodarone results in decreased expression of BCL2 protein
[3-methyladenine co-treated with Amiodarone] results in decreased expression of BCL2 protein; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 protein]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 mRNA]]
CTD PMID:21224497 PMID:23912912 PMID:34434487 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCL2L11 BCL2 like 11 increases expression EXP Amiodarone results in increased expression of BCL2L11 mRNA CTD PMID:19774075 NCBI chr 2:111,120,914...111,168,445
Ensembl chr 2:111,119,378...111,168,444
JBrowse link
G BCL3 BCL3 transcription coactivator increases expression ISO Amiodarone results in increased expression of BCL3 mRNA CTD PMID:22015988 NCBI chr19:44,747,705...44,760,044
Ensembl chr19:44,747,705...44,760,044
JBrowse link
G BCL6B BCL6B transcription repressor affects expression ISO Amiodarone affects the expression of BCL6B mRNA CTD PMID:19483382 NCBI chr17:7,023,050...7,029,644
Ensembl chr17:7,023,050...7,030,290
JBrowse link
G BCO1 beta-carotene oxygenase 1 decreases expression ISO Amiodarone results in decreased expression of BCO1 mRNA CTD PMID:24535564 NCBI chr16:81,238,689...81,291,142
Ensembl chr16:81,238,689...81,291,142
JBrowse link
G BDNF brain derived neurotrophic factor affects expression ISO Amiodarone affects the expression of BDNF mRNA CTD PMID:31324950 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
JBrowse link
G BHLHE40 basic helix-loop-helix family member e40 increases expression EXP Amiodarone results in increased expression of BHLHE40 mRNA CTD PMID:19774075 NCBI chr 3:4,979,437...4,985,323
Ensembl chr 3:4,979,437...4,985,323
JBrowse link
G BHMT betaine--homocysteine S-methyltransferase affects expression ISO Amiodarone affects the expression of BHMT mRNA CTD PMID:18355885 NCBI chr 5:79,111,809...79,132,288
Ensembl chr 5:79,111,809...79,132,288
JBrowse link
G BID BH3 interacting domain death agonist multiple interactions EXP [TNFSF10 co-treated with Amiodarone] results in increased cleavage of BID protein CTD PMID:21292685 NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770
JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 decreases expression ISO Amiodarone results in decreased expression of BIRC5 protein CTD PMID:21224497 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636
JBrowse link
G BLTP3B bridge-like lipid transfer protein family member 3B affects expression ISO Amiodarone affects the expression of BLTP3B mRNA CTD PMID:19483382 NCBI chr12:100,037,072...100,142,874
Ensembl chr12:100,028,455...100,142,874
JBrowse link
G BMF Bcl2 modifying factor affects expression ISO Amiodarone affects the expression of BMF mRNA CTD PMID:19483382 NCBI chr15:40,087,890...40,108,879
Ensembl chr15:40,087,890...40,108,892
JBrowse link
G BMP2K BMP2 inducible kinase increases expression EXP Amiodarone results in increased expression of BMP2K mRNA CTD PMID:19774075 NCBI chr 4:78,776,350...78,916,365
Ensembl chr 4:78,776,342...78,916,365
JBrowse link
G BNIP3 BCL2 interacting protein 3 affects expression ISO Amiodarone affects the expression of BNIP3 mRNA CTD PMID:19483382 NCBI chr10:131,967,684...131,981,923
Ensembl chr10:131,967,684...131,981,967
JBrowse link
G BOLA2 bolA family member 2 increases expression EXP Amiodarone results in increased expression of BOLA2 mRNA CTD PMID:19774075 NCBI chr16:29,453,588...29,454,964
Ensembl chr16:30,192,932...30,194,306
Ensembl chr16:30,192,932...30,194,306
JBrowse link
G BOLL boule homolog, RNA binding protein increases expression EXP Amiodarone results in increased expression of BOLL mRNA CTD PMID:19774075 NCBI chr 2:197,726,890...197,786,206
Ensembl chr 2:197,726,879...197,786,762
JBrowse link
G BRCA1 BRCA1 DNA repair associated increases expression ISO Amiodarone results in increased expression of BRCA1 mRNA CTD PMID:24489787 NCBI chr17:43,044,295...43,170,327
Ensembl chr17:43,044,295...43,170,245
JBrowse link
G BRCC3 BRCA1/BRCA2-containing complex subunit 3 increases expression EXP Amiodarone results in increased expression of BRCC3 mRNA CTD PMID:19774075 NCBI chr  X:155,071,508...155,123,077
Ensembl chr  X:155,071,420...155,123,077
JBrowse link
G BRPF1 bromodomain and PHD finger containing 1 increases expression EXP Amiodarone results in increased expression of BRPF1 mRNA CTD PMID:19774075 NCBI chr 3:9,731,735...9,748,015
Ensembl chr 3:9,731,729...9,748,019
JBrowse link
G BSG basigin (Ok blood group) increases expression EXP Amiodarone results in increased expression of BSG mRNA CTD PMID:19774075 NCBI chr19:571,283...583,493
Ensembl chr19:571,277...583,494
JBrowse link
G BTF3 basic transcription factor 3 affects expression ISO Amiodarone affects the expression of BTF3 mRNA CTD PMID:19483382 NCBI chr 5:73,498,442...73,505,667
Ensembl chr 5:73,498,408...73,505,667
JBrowse link
G C11orf16 chromosome 11 open reading frame 16 increases expression EXP Amiodarone results in increased expression of C11ORF16 mRNA CTD PMID:19774075 NCBI chr11:8,920,076...8,932,947
Ensembl chr11:8,920,076...8,933,006
JBrowse link
G C16orf74 chromosome 16 open reading frame 74 increases expression EXP Amiodarone results in increased expression of C16ORF74 mRNA CTD PMID:19774075 NCBI chr16:85,707,517...85,751,096
Ensembl chr16:85,690,084...85,751,129
JBrowse link
G C1QBP complement C1q binding protein affects expression ISO Amiodarone affects the expression of C1QBP mRNA CTD PMID:19483382 NCBI chr17:5,432,777...5,439,155
Ensembl chr17:5,432,777...5,448,830
JBrowse link
G C1S complement C1s affects expression ISO Amiodarone affects the expression of C1S mRNA CTD PMID:19483382 NCBI chr12:7,060,718...7,071,032
Ensembl chr12:6,988,259...7,071,032
JBrowse link
G C21orf91 chromosome 21 open reading frame 91 increases expression EXP Amiodarone results in increased expression of C21ORF91 mRNA CTD PMID:19774075 NCBI chr21:17,788,974...17,819,356
Ensembl chr21:17,788,974...17,819,386
JBrowse link
G C2CD2 C2 calcium dependent domain containing 2 affects expression ISO Amiodarone affects the expression of C2CD2 mRNA CTD PMID:19483382 NCBI chr21:41,885,112...41,954,018
Ensembl chr21:41,885,112...41,954,018
JBrowse link
G C2CD4B C2 calcium dependent domain containing 4B increases expression EXP Amiodarone results in increased expression of NLF2 mRNA CTD PMID:19774075 NCBI chr15:62,163,535...62,165,285
Ensembl chr15:62,163,535...62,165,285
JBrowse link
G C3orf18 chromosome 3 open reading frame 18 increases expression EXP Amiodarone results in increased expression of C3ORF18 mRNA CTD PMID:19774075 NCBI chr 3:50,558,025...50,574,700
Ensembl chr 3:50,558,025...50,571,027
JBrowse link
G C3orf33 chromosome 3 open reading frame 33 increases expression EXP Amiodarone results in increased expression of C3ORF33 mRNA CTD PMID:19774075 NCBI chr 3:155,762,617...155,806,278
Ensembl chr 3:155,762,617...155,806,278
JBrowse link
G C4BPA complement component 4 binding protein alpha affects expression ISO Amiodarone affects the expression of C4BPA mRNA CTD PMID:19483382 NCBI chr 1:207,104,233...207,144,972
Ensembl chr 1:207,104,233...207,144,972
JBrowse link
G C6orf141 chromosome 6 open reading frame 141 increases expression EXP Amiodarone results in increased expression of C6ORF141 mRNA CTD PMID:19774075 NCBI chr 6:49,550,668...49,561,916
Ensembl chr 6:49,550,666...49,561,907
JBrowse link
G C7 complement C7 affects expression ISO Amiodarone affects the expression of C7 mRNA CTD PMID:19483382 NCBI chr 5:40,909,497...40,984,643
Ensembl chr 5:40,909,492...41,020,216
JBrowse link
G C8B complement C8 beta chain affects expression
decreases expression
ISO Amiodarone affects the expression of C8B mRNA
Amiodarone results in decreased expression of C8B mRNA
CTD PMID:19483382 PMID:24535564 NCBI chr 1:56,929,207...56,966,015
Ensembl chr 1:56,929,207...56,974,383
JBrowse link
G CA2 carbonic anhydrase 2 affects expression ISO Amiodarone affects the expression of CA2 mRNA CTD PMID:19483382 NCBI chr 8:85,464,007...85,481,493
Ensembl chr 8:85,463,968...85,481,493
JBrowse link
G CA3 carbonic anhydrase 3 affects expression
increases expression
ISO Amiodarone affects the expression of CAR3 mRNA
Amiodarone results in increased expression of CAR3 protein
CTD PMID:16538043 PMID:19483382 NCBI chr 8:85,438,859...85,449,040
Ensembl chr 8:85,373,436...85,449,040
JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C decreases expression ISO Amiodarone results in decreased expression of CACNA1C mRNA CTD PMID:15520326 NCBI chr12:1,970,780...2,697,950
Ensembl chr12:1,970,772...2,697,950
JBrowse link
G CADPS2 calcium dependent secretion activator 2 affects expression ISO Amiodarone affects the expression of CADPS2 mRNA CTD PMID:19483382 NCBI chr 7:122,318,411...122,886,460
Ensembl chr 7:122,318,411...122,886,759
JBrowse link
G CALR calreticulin increases expression EXP Amiodarone results in increased expression of CALR mRNA CTD PMID:36586010 NCBI chr19:12,938,609...12,944,489
Ensembl chr19:12,938,578...12,944,489
JBrowse link
G CAMK2A calcium/calmodulin dependent protein kinase II alpha increases expression EXP Amiodarone results in increased expression of CAMK2A mRNA CTD PMID:19774075 NCBI chr 5:150,219,491...150,290,130
Ensembl chr 5:150,219,491...150,290,093
JBrowse link
G CAPN11 calpain 11 increases expression EXP Amiodarone results in increased expression of CAPN11 mRNA CTD PMID:19774075 NCBI chr 6:44,158,820...44,184,401
Ensembl chr 6:44,158,811...44,184,401
JBrowse link
G CAPN3 calpain 3 increases expression EXP Amiodarone results in increased expression of CAPN3 mRNA CTD PMID:19774075 NCBI chr15:42,359,501...42,412,317
Ensembl chr15:42,359,498...42,412,949
JBrowse link
G CAPRIN1 cell cycle associated protein 1 affects expression ISO Amiodarone affects the expression of CAPRIN1 mRNA CTD PMID:19483382 NCBI chr11:34,051,731...34,102,610
Ensembl chr11:34,051,731...34,102,610
JBrowse link
G CARD9 caspase recruitment domain family member 9 increases expression EXP Amiodarone results in increased expression of CARD9 mRNA CTD PMID:19774075 NCBI chr 9:136,363,956...136,373,669
Ensembl chr 9:136,363,956...136,373,681
JBrowse link
G CASKIN2 CASK interacting protein 2 increases expression EXP Amiodarone results in increased expression of CASKIN2 mRNA CTD PMID:19774075 NCBI chr17:75,500,261...75,515,537
Ensembl chr17:75,500,261...75,515,537
JBrowse link
G CASP3 caspase 3 affects expression
increases cleavage
increases activity
increases expression
decreases expression
multiple interactions
ISO
EXP
Amiodarone affects the expression of CASP3 mRNA
Amiodarone results in increased cleavage of CASP3 protein
Amiodarone results in increased activity of CASP3 protein
Amiodarone results in increased expression of CASP3 mRNA
Amiodarone results in decreased expression of CASP3 protein modified form
3-methyladenine promotes the reaction [Amiodarone results in increased cleavage of CASP3 protein]; [TNFSF10 co-treated with Amiodarone] results in increased cleavage of CASP3 protein; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 protein]; alpha-Tocopherol promotes the reaction [Amiodarone results in increased activity of CASP3 protein]; alpha-Tocopherol promotes the reaction [TNF protein promotes the reaction [Amiodarone results in increased activity of CASP3 protein]]; Amiodarone results in increased activity of and results in increased cleavage of CASP3 protein; ATG7 protein affects the reaction [Amiodarone results in increased cleavage of CASP3 protein]; Chloroquine promotes the reaction [Amiodarone results in increased cleavage of CASP3 protein]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 mRNA]]; TNF protein promotes the reaction [Amiodarone results in increased activity of CASP3 protein]
Amiodarone results in increased expression of CASP3 mRNA; Amiodarone results in increased expression of CASP3 protein
CTD PMID:12084619 PMID:12747577 PMID:19483382 PMID:19815060 PMID:21224497 More... NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CASP7 caspase 7 multiple interactions
increases expression
increases activity
EXP
ISO
alpha-Tocopherol promotes the reaction [Amiodarone results in increased activity of CASP7 protein]; alpha-Tocopherol promotes the reaction [TNF protein promotes the reaction [Amiodarone results in increased activity of CASP7 protein]]; TNF protein promotes the reaction [Amiodarone results in increased activity of CASP7 protein]
Amiodarone results in increased expression of CASP7 mRNA
CTD PMID:23042730 PMID:23135547 PMID:24489787 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907
JBrowse link
G CASP8 caspase 8 multiple interactions
increases expression
EXP
ISO
[TNFSF10 co-treated with Amiodarone] results in increased cleavage of CASP8 protein
Amiodarone results in increased expression of CASP8 protein modified form
CTD PMID:21224497 PMID:21292685 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836
JBrowse link
G CASP9 caspase 9 increases expression
multiple interactions
EXP
ISO
Amiodarone results in increased expression of CASP9 mRNA
[Amiodarone co-treated with TNF protein] results in increased activity of CASP9 protein
[TNFSF10 co-treated with Amiodarone] results in increased cleavage of CASP9 protein
CTD PMID:19774075 PMID:21292685 PMID:23042730 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CAT catalase multiple interactions
decreases expression
decreases activity
ISO
EXP
Amiodarone inhibits the reaction [Indomethacin results in increased activity of CAT protein]
ADM2 protein inhibits the reaction [Amiodarone results in decreased activity of CAT protein]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of CAT mRNA]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased activity of CAT protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of CAT mRNA]]
CTD PMID:18087811 PMID:34434487 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CAV3 caveolin 3 increases expression EXP Amiodarone results in increased expression of CAV3 mRNA CTD PMID:19774075 NCBI chr 3:8,733,802...8,746,758
Ensembl chr 3:8,733,802...8,841,808
JBrowse link
G CBR1 carbonyl reductase 1 affects expression ISO Amiodarone affects the expression of CBR1 mRNA CTD PMID:19483382 NCBI chr21:36,070,024...36,073,164
Ensembl chr21:36,069,941...36,073,166
JBrowse link
G CCDC134 coiled-coil domain containing 134 increases expression EXP Amiodarone results in increased expression of CCDC134 mRNA CTD PMID:19774075 NCBI chr22:41,800,679...41,832,164
Ensembl chr22:41,800,679...41,832,164
JBrowse link
G CCDC17 coiled-coil domain containing 17 increases expression EXP Amiodarone results in increased expression of CCDC17 mRNA CTD PMID:19774075 NCBI chr 1:45,620,044...45,624,054
Ensembl chr 1:45,620,044...45,624,057
JBrowse link
G CCDC197 coiled-coil domain containing 197 increases expression EXP Amiodarone results in increased expression of CCDC197 mRNA CTD PMID:19774075 NCBI chr14:93,987,225...94,011,695
Ensembl chr14:93,987,225...94,008,863
JBrowse link
G CCDC9 coiled-coil domain containing 9 increases expression EXP Amiodarone results in increased expression of CCDC9 mRNA CTD PMID:19774075 NCBI chr19:47,256,525...47,275,723
Ensembl chr19:47,255,980...47,273,701
JBrowse link
G CCL2 C-C motif chemokine ligand 2 multiple interactions
increases expression
EXP
ISO
Amiodarone inhibits the reaction [CRP protein results in increased expression of CCL2 protein]
[Amiodarone co-treated with Dexamethasone] results in increased expression of CCL2 mRNA
Amiodarone results in increased expression of CCL2 mRNA
CTD PMID:19225199 PMID:23397585 PMID:25900201 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
JBrowse link
G CCN2 cellular communication network factor 2 increases expression ISO Amiodarone results in increased expression of CCN2 mRNA CTD PMID:32909452 NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372
JBrowse link
G CCNT1 cyclin T1 increases expression EXP Amiodarone results in increased expression of CCNT1 mRNA CTD PMID:19774075 NCBI chr12:48,688,458...48,716,707
Ensembl chr12:48,688,458...48,716,998
JBrowse link
G CCR9 C-C motif chemokine receptor 9 increases expression EXP Amiodarone results in increased expression of CCR9 mRNA CTD PMID:19774075 NCBI chr 3:45,886,064...45,903,174
Ensembl chr 3:45,884,425...45,903,174
JBrowse link
G CD320 CD320 molecule increases expression EXP Amiodarone results in increased expression of CD320 mRNA CTD PMID:19774075 NCBI chr19:8,302,127...8,308,358
Ensembl chr19:8,302,127...8,308,358
JBrowse link
G CD36 CD36 molecule (CD36 blood group) increases expression
decreases expression
ISO
EXP
Amiodarone results in increased expression of CD36 mRNA; Amiodarone results in increased expression of CD36 protein
Amiodarone results in decreased expression of CD36 mRNA
CTD PMID:24535564 PMID:29248575 PMID:32535746 PMID:34259586 NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277
JBrowse link
G CD86 CD86 molecule multiple interactions EXP [Amiodarone co-treated with CYP3A4 protein] results in increased expression of CD86 protein CTD PMID:22785256 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139
JBrowse link
G CDA cytidine deaminase increases expression ISO Amiodarone results in increased expression of CDA mRNA CTD PMID:24535564 NCBI chr 1:20,589,097...20,618,903
Ensembl chr 1:20,589,086...20,618,903
JBrowse link
G CDC25A cell division cycle 25A increases expression EXP Amiodarone results in increased expression of CDC25A mRNA CTD PMID:19774075 NCBI chr 3:48,157,146...48,188,417
Ensembl chr 3:48,157,146...48,188,417
JBrowse link
G CDC42SE1 CDC42 small effector 1 increases expression EXP Amiodarone results in increased expression of CDC42SE1 mRNA CTD PMID:19774075 NCBI chr 1:151,050,985...151,059,622
Ensembl chr 1:151,050,971...151,070,325
JBrowse link
G CDH1 cadherin 1 increases expression
multiple interactions
ISO
EXP
Amiodarone results in increased expression of CDH1 protein
6-bromoindirubin-3'-oxime inhibits the reaction [Amiodarone results in increased expression of CDH1 protein]
CTD PMID:26515726 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537
JBrowse link
G CDH15 cadherin 15 increases expression EXP Amiodarone results in increased expression of CDH15 mRNA CTD PMID:19774075 NCBI chr16:89,171,748...89,195,492
Ensembl chr16:89,171,748...89,195,492
JBrowse link
G CDH2 cadherin 2 decreases expression ISO
EXP
Amiodarone results in decreased expression of CDH2 protein CTD PMID:26515726 NCBI chr18:27,932,879...28,177,130
Ensembl chr18:27,932,879...28,177,946
JBrowse link
G CDH26 cadherin 26 increases expression EXP Amiodarone results in increased expression of CDH26 mRNA CTD PMID:19774075 NCBI chr20:59,958,423...60,035,934
Ensembl chr20:59,958,423...60,034,011
JBrowse link
G CDK17 cyclin dependent kinase 17 increases expression EXP Amiodarone results in increased expression of CDK17 mRNA CTD PMID:19774075 NCBI chr12:96,278,225...96,400,439
Ensembl chr12:96,278,261...96,400,480
JBrowse link
G CDKN2C cyclin dependent kinase inhibitor 2C affects expression ISO Amiodarone affects the expression of CDKN2C mRNA CTD PMID:18355885 NCBI chr 1:50,960,745...50,974,634
Ensembl chr 1:50,960,745...50,974,634
JBrowse link
G CDO1 cysteine dioxygenase type 1 affects expression ISO Amiodarone affects the expression of CDO1 mRNA CTD PMID:19483382 NCBI chr 5:115,804,733...115,816,659
Ensembl chr 5:115,804,733...115,816,659
JBrowse link
G CEBPB CCAAT enhancer binding protein beta increases expression EXP
ISO
Amiodarone results in increased expression of CEBPB mRNA CTD PMID:19774075 PMID:25580480 NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,734...50,192,690
JBrowse link
G CELF6 CUGBP Elav-like family member 6 increases expression EXP Amiodarone results in increased expression of CELF6 mRNA CTD PMID:19774075 NCBI chr15:72,284,727...72,320,157
Ensembl chr15:72,284,727...72,320,157
JBrowse link
G CEPT1 choline/ethanolamine phosphotransferase 1 affects expression ISO Amiodarone affects the expression of CEPT1 mRNA CTD PMID:19483382 NCBI chr 1:111,139,499...111,185,104
Ensembl chr 1:111,139,479...111,185,104
JBrowse link
G CES1 carboxylesterase 1 increases expression EXP Amiodarone results in increased expression of CES1 mRNA CTD PMID:21163907 NCBI chr16:55,802,851...55,833,096
Ensembl chr16:55,802,851...55,833,337
JBrowse link
G CES2 carboxylesterase 2 affects expression ISO Amiodarone affects the expression of CES2 mRNA CTD PMID:18355885 PMID:19483382 NCBI chr16:66,934,471...66,945,096
Ensembl chr16:66,934,444...66,945,096
JBrowse link
G CFAP184 cilia and flagella associated protein 184 increases expression EXP Amiodarone results in increased expression of CFAP184 mRNA CTD PMID:19774075 NCBI chr 4:7,040,849...7,043,001
Ensembl chr 4:7,040,849...7,043,001
JBrowse link
G CFI complement factor I affects expression ISO Amiodarone affects the expression of CFI mRNA CTD PMID:19483382 NCBI chr 4:109,730,982...109,801,999
Ensembl chr 4:109,731,008...109,802,150
JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator decreases expression ISO Amiodarone results in decreased expression of CFLAR protein CTD PMID:21224497 NCBI chr 2:201,116,164...201,176,687
Ensembl chr 2:201,116,154...201,176,687
JBrowse link
G CGA glycoprotein hormones, alpha polypeptide increases expression ISO Amiodarone results in increased expression of CGA mRNA CTD PMID:3427795 NCBI chr 6:87,085,498...87,095,106
Ensembl chr 6:87,085,498...87,095,106
JBrowse link
G CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 increases expression EXP Amiodarone results in increased expression of CHAC1 mRNA CTD PMID:19774075 PMID:36586010 NCBI chr15:40,953,471...40,956,512
Ensembl chr15:40,952,962...40,956,512
JBrowse link
G CHAF1A chromatin assembly factor 1 subunit A decreases expression ISO Amiodarone results in decreased expression of CHAF1A mRNA CTD PMID:17991464 NCBI chr19:4,402,640...4,450,830
Ensembl chr19:4,402,640...4,445,018
JBrowse link
G CHAT choline O-acetyltransferase decreases expression ISO Amiodarone results in decreased expression of CHAT protein CTD PMID:25659768 NCBI chr10:49,609,095...49,667,942
Ensembl chr10:49,609,095...49,667,942
JBrowse link
G CHGA chromogranin A increases expression EXP Amiodarone results in increased expression of CHGA mRNA CTD PMID:19774075 NCBI chr14:92,922,664...92,935,285
Ensembl chr14:92,923,150...92,935,285
JBrowse link
G CHP1 calcineurin like EF-hand protein 1 affects expression ISO Amiodarone affects the expression of CHP1 mRNA CTD PMID:19483382 NCBI chr15:41,231,268...41,281,887
Ensembl chr15:41,230,839...41,281,887
JBrowse link
G CHRNB3 cholinergic receptor nicotinic beta 3 subunit increases expression EXP Amiodarone results in increased expression of CHRNB3 mRNA CTD PMID:19774075 NCBI chr 8:42,697,366...42,737,407
Ensembl chr 8:42,697,366...42,737,407
JBrowse link
G CHST6 carbohydrate sulfotransferase 6 increases expression EXP Amiodarone results in increased expression of CHST6 mRNA CTD PMID:19774075 NCBI chr16:75,472,042...75,495,441
Ensembl chr16:75,472,052...75,495,445
JBrowse link
G CIDEA cell death inducing DFFA like effector a multiple interactions
increases expression
ISO 1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of CIDEA mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of CIDEA mRNA] CTD PMID:28962527 NCBI chr18:12,254,361...12,277,595
Ensembl chr18:12,254,361...12,277,595
JBrowse link
G CIDEC cell death inducing DFFA like effector c increases expression
multiple interactions
ISO Amiodarone results in increased expression of CIDEC mRNA; Amiodarone results in increased expression of CIDEC protein
1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of CIDEC mRNA]; 4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased expression of CIDEC mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of CIDEC mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of CIDEC protein]
CTD PMID:28962527 NCBI chr 3:9,866,710...9,880,253
Ensembl chr 3:9,866,711...9,880,255
JBrowse link
G CIMAP3 ciliary microtubule associated protein 3 increases expression EXP Amiodarone results in increased expression of CIMAP3 mRNA CTD PMID:19774075 NCBI chr 1:111,324,663...111,353,017
Ensembl chr 1:111,346,600...111,353,013
JBrowse link
G CISD1 CDGSH iron sulfur domain 1 affects expression ISO Amiodarone affects the expression of CISD1 mRNA CTD PMID:19483382 NCBI chr10:58,269,162...58,289,586
Ensembl chr10:58,269,162...58,289,586
JBrowse link
G CLCN4 chloride voltage-gated channel 4 affects expression ISO Amiodarone affects the expression of CLCN4 mRNA CTD PMID:19483382 NCBI chr  X:10,156,975...10,237,660
Ensembl chr  X:10,156,975...10,237,660
JBrowse link
G CLCN5 chloride voltage-gated channel 5 increases expression EXP Amiodarone results in increased expression of CLCN5 mRNA CTD PMID:19774075 NCBI chr  X:49,922,596...50,099,230
Ensembl chr  X:49,922,596...50,099,235
JBrowse link
G CLCN6 chloride voltage-gated channel 6 increases expression EXP Amiodarone results in increased expression of CLCN6 mRNA CTD PMID:19774075 NCBI chr 1:11,806,191...11,843,130
Ensembl chr 1:11,806,096...11,848,079
JBrowse link
G CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit affects expression ISO Amiodarone affects the expression of CLPP mRNA CTD PMID:19483382 NCBI chr19:6,361,531...6,370,242
Ensembl chr19:6,361,427...6,370,242
JBrowse link
G CLPTM1L CLPTM1 like affects expression ISO Amiodarone affects the expression of CLPTM1L mRNA CTD PMID:19483382 NCBI chr 5:1,317,752...1,345,099
Ensembl chr 5:1,317,752...1,345,099
JBrowse link
G CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit X increases expression ISO Amiodarone results in increased expression of CLPX mRNA CTD PMID:24535564 NCBI chr15:65,148,219...65,185,342
Ensembl chr15:65,148,219...65,185,342
JBrowse link
G CLTCL1 clathrin heavy chain like 1 increases expression EXP Amiodarone results in increased expression of CLTCL1 mRNA CTD PMID:19774075 NCBI chr22:19,179,473...19,291,719
Ensembl chr22:19,179,473...19,291,719
JBrowse link
G CLVS2 clavesin 2 increases expression EXP Amiodarone results in increased expression of CLVS2 mRNA CTD PMID:19774075 NCBI chr 6:122,996,235...123,072,925
Ensembl chr 6:122,996,235...123,072,925
JBrowse link
G CMBL carboxymethylenebutenolidase homolog affects expression
increases expression
ISO Amiodarone affects the expression of CMBL mRNA
Amiodarone results in increased expression of CMBL mRNA
CTD PMID:19483382 PMID:24535564 NCBI chr 5:10,277,595...10,307,902
Ensembl chr 5:10,275,875...10,307,902
JBrowse link
G CMPK1 cytidine/uridine monophosphate kinase 1 affects expression ISO Amiodarone affects the expression of CMPK1 mRNA CTD PMID:19483382 NCBI chr 1:47,333,790...47,378,839
Ensembl chr 1:47,333,790...47,394,866
JBrowse link
G CMTM6 CKLF like MARVEL transmembrane domain containing 6 affects expression ISO Amiodarone affects the expression of CMTM6 mRNA CTD PMID:18355885 NCBI chr 3:32,481,312...32,502,852
Ensembl chr 3:32,481,312...32,502,852
JBrowse link
G CMTM7 CKLF like MARVEL transmembrane domain containing 7 increases expression EXP Amiodarone results in increased expression of CMTM7 mRNA CTD PMID:19774075 NCBI chr 3:32,391,853...32,455,528
Ensembl chr 3:32,391,698...32,483,067
JBrowse link
G CMYA5 cardiomyopathy associated 5 increases expression EXP Amiodarone results in increased expression of CMYA5 mRNA CTD PMID:19774075 NCBI chr 5:79,689,836...79,800,222
Ensembl chr 5:79,689,836...79,800,240
JBrowse link
G CNIH3 cornichon family AMPA receptor auxiliary protein 3 increases expression EXP Amiodarone results in increased expression of CNIH3 mRNA CTD PMID:19774075 NCBI chr 1:224,434,640...224,740,554
Ensembl chr 1:224,434,660...224,740,554
JBrowse link
G CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 increases expression EXP Amiodarone results in increased expression of CNNM2 mRNA CTD PMID:19774075 NCBI chr10:102,918,294...103,090,222
Ensembl chr10:102,918,294...103,090,222
JBrowse link
G CNOT7 CCR4-NOT transcription complex subunit 7 increases expression EXP Amiodarone results in increased expression of CNOT7 mRNA CTD PMID:19774075 NCBI chr 8:17,224,966...17,246,857
Ensembl chr 8:17,224,966...17,246,878
JBrowse link
G CNP 2',3'-cyclic nucleotide 3' phosphodiesterase increases expression EXP Amiodarone results in increased expression of CNP mRNA CTD PMID:19774075 NCBI chr17:41,966,795...41,977,740
Ensembl chr17:41,966,763...41,977,740
JBrowse link
G COL11A1 collagen type XI alpha 1 chain increases expression EXP Amiodarone results in increased expression of COL11A1 mRNA CTD PMID:19774075 NCBI chr 1:102,876,473...103,108,522
Ensembl chr 1:102,876,467...103,108,872
JBrowse link
G COL1A1 collagen type I alpha 1 chain increases expression ISO Amiodarone results in increased expression of COL1A1 mRNA CTD PMID:32909452 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
JBrowse link
G COL27A1 collagen type XXVII alpha 1 chain increases expression EXP Amiodarone results in increased expression of COL27A1 mRNA CTD PMID:19774075 NCBI chr 9:114,154,098...114,312,511
Ensembl chr 9:114,155,537...114,312,511
JBrowse link
G COL8A2 collagen type VIII alpha 2 chain increases expression EXP Amiodarone results in increased expression of COL8A2 mRNA CTD PMID:19774075 NCBI chr 1:36,095,239...36,125,222
Ensembl chr 1:36,095,239...36,125,222
JBrowse link
G COPG1 COPI coat complex subunit gamma 1 affects expression ISO Amiodarone affects the expression of COPG1 mRNA CTD PMID:19483382 NCBI chr 3:129,249,606...129,277,773
Ensembl chr 3:129,249,606...129,277,773
JBrowse link
G COPS4 COP9 signalosome subunit 4 affects expression ISO Amiodarone affects the expression of COPS4 mRNA CTD PMID:19483382 NCBI chr 4:83,035,183...83,075,818
Ensembl chr 4:83,034,447...83,075,818
JBrowse link
G COPZ2 COPI coat complex subunit zeta 2 increases expression ISO Amiodarone results in increased expression of COPZ2 mRNA CTD PMID:24535564 NCBI chr17:48,026,167...48,048,053
Ensembl chr17:48,026,167...48,038,030
JBrowse link
G COQ2 coenzyme Q2, polyprenyltransferase increases expression ISO Amiodarone results in increased expression of COQ2 mRNA CTD PMID:24489787 NCBI chr 4:83,263,824...83,285,134
Ensembl chr 4:83,261,536...83,284,914
JBrowse link
G COQ3 coenzyme Q3, methyltransferase affects expression
increases expression
ISO Amiodarone affects the expression of COQ3 mRNA
Amiodarone results in increased expression of COQ3 mRNA
CTD PMID:19483382 PMID:24489787 NCBI chr 6:99,369,401...99,394,195
Ensembl chr 6:99,369,401...99,394,195
JBrowse link
G CORO2A coronin 2A increases expression EXP Amiodarone results in increased expression of CORO2A mRNA CTD PMID:19774075 NCBI chr 9:98,120,975...98,192,637
Ensembl chr 9:98,120,975...98,192,637
JBrowse link
G CORT cortistatin affects expression ISO Amiodarone affects the expression of CORT mRNA CTD PMID:31324950 NCBI chr 1:10,450,031...10,451,998
Ensembl chr 1:10,450,031...10,451,998
JBrowse link
G COX15 cytochrome c oxidase assembly homolog COX15 increases expression ISO Amiodarone results in increased expression of COX15 mRNA CTD PMID:24489787 NCBI chr10:99,694,293...99,732,127
Ensembl chr10:99,710,868...99,732,127
JBrowse link
G COX17 cytochrome c oxidase copper chaperone COX17 increases expression ISO Amiodarone results in increased expression of COX17 mRNA CTD PMID:24489787 NCBI chr 3:119,663,975...119,677,406
Ensembl chr 3:119,654,513...119,677,454
JBrowse link
G COX4I1 cytochrome c oxidase subunit 4I1 affects expression ISO Amiodarone affects the expression of COX4I1 mRNA CTD PMID:19483382 NCBI chr16:85,799,695...85,807,068
Ensembl chr16:85,798,633...85,807,068
JBrowse link
G COX6B2 cytochrome c oxidase subunit 6B2 increases expression ISO Amiodarone results in increased expression of COX6B2 mRNA CTD PMID:24535564 NCBI chr19:55,349,704...55,354,719
Ensembl chr19:55,349,306...55,354,719
JBrowse link
G CPLX2 complexin 2 increases expression EXP Amiodarone results in increased expression of CPLX2 mRNA CTD PMID:19774075 NCBI chr 5:175,796,533...175,884,021
Ensembl chr 5:175,796,310...175,884,021
JBrowse link
G CPN1 carboxypeptidase N subunit 1 affects expression ISO Amiodarone affects the expression of CPN1 mRNA CTD PMID:19483382 NCBI chr10:100,042,193...100,081,869
Ensembl chr10:100,042,193...100,081,869
JBrowse link
G CPPED1 calcineurin like phosphoesterase domain containing 1 affects expression ISO Amiodarone affects the expression of CPPED1 mRNA CTD PMID:18355885 NCBI chr16:12,659,799...12,803,887
Ensembl chr16:12,659,799...12,803,887
JBrowse link
G CPQ carboxypeptidase Q affects expression ISO Amiodarone affects the expression of CPQ mRNA CTD PMID:19483382 NCBI chr 8:96,645,242...97,143,501
Ensembl chr 8:96,645,242...97,149,654
JBrowse link
G CPT1A carnitine palmitoyltransferase 1A increases expression
decreases expression
affects expression
ISO
EXP
Amiodarone results in increased expression of CPT1A mRNA
Amiodarone results in decreased expression of CPT1A mRNA
Amiodarone affects the expression of CPT1A mRNA
CTD PMID:24489787 PMID:29248575 PMID:32084307 NCBI chr11:68,754,620...68,844,277
Ensembl chr11:68,754,620...68,844,410
JBrowse link
G CPT2 carnitine palmitoyltransferase 2 increases expression
decreases expression
ISO Amiodarone results in increased expression of CPT2 mRNA
Amiodarone results in decreased expression of CPT2 mRNA
CTD PMID:24489787 PMID:30685923 PMID:32084307 NCBI chr 1:53,196,824...53,214,197
Ensembl chr 1:53,196,792...53,214,197
JBrowse link
G CRB3 crumbs cell polarity complex component 3 increases expression EXP Amiodarone results in increased expression of CRB3 mRNA CTD PMID:19774075 NCBI chr19:6,463,777...6,467,221
Ensembl chr19:6,463,777...6,467,221
JBrowse link
G CREM cAMP responsive element modulator affects expression ISO Amiodarone affects the expression of CREM mRNA CTD PMID:18355885 PMID:19483382 NCBI chr10:35,126,846...35,212,958
Ensembl chr10:35,126,791...35,212,958
JBrowse link
G CROT carnitine O-octanoyltransferase decreases expression EXP Amiodarone results in decreased expression of CROT mRNA CTD PMID:27089845 NCBI chr 7:87,345,664...87,399,794
Ensembl chr 7:87,345,664...87,399,794
JBrowse link
G CRP C-reactive protein multiple interactions EXP Amiodarone inhibits the reaction [CRP protein results in increased expression of CCL2 protein]; Amiodarone inhibits the reaction [CRP protein results in increased expression of TNF protein] CTD PMID:19225199 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589
JBrowse link
G CRTC1 CREB regulated transcription coactivator 1 decreases expression ISO Amiodarone results in decreased expression of CRTC1 mRNA CTD PMID:17991464 NCBI chr19:18,683,680...18,782,333
Ensembl chr19:18,683,678...18,782,333
JBrowse link
G CSNK2B casein kinase 2 beta affects expression ISO Amiodarone affects the expression of CSNK2B mRNA CTD PMID:19483382 NCBI chr 6:31,666,080...31,670,067
Ensembl chr 6:31,665,227...31,670,343
JBrowse link
G CSRP1 cysteine and glycine rich protein 1 affects expression ISO Amiodarone affects the expression of CSRP1 mRNA CTD PMID:19483382 NCBI chr 1:201,483,530...201,507,123
Ensembl chr 1:201,483,530...201,509,456
JBrowse link
G CSRP3 cysteine and glycine rich protein 3 increases expression ISO Amiodarone results in increased expression of CSRP3 mRNA CTD PMID:24535564 NCBI chr11:19,182,030...19,201,983
Ensembl chr11:19,182,030...19,210,571
JBrowse link
G CST6 cystatin E/M increases expression EXP Amiodarone results in increased expression of CST6 mRNA CTD PMID:19774075 NCBI chr11:66,012,008...66,013,505
Ensembl chr11:66,012,008...66,013,505
JBrowse link
G CST7 cystatin F increases expression EXP Amiodarone results in increased expression of CST7 mRNA CTD PMID:19774075 NCBI chr20:24,949,269...24,959,928
Ensembl chr20:24,949,269...24,959,928
JBrowse link
G CTC1 CST telomere replication complex component 1 increases expression EXP Amiodarone results in increased expression of CTC1 mRNA CTD PMID:19774075 NCBI chr17:8,224,815...8,248,056
Ensembl chr17:8,224,815...8,248,058
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 increases expression EXP Amiodarone results in increased expression of CTLA4 mRNA CTD PMID:19774075 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,853,888...203,873,965
JBrowse link
G CTNNA1 catenin alpha 1 affects expression ISO Amiodarone affects the expression of CTNNA1 mRNA CTD PMID:19483382 NCBI chr 5:138,753,425...138,935,034
Ensembl chr 5:138,610,967...138,935,034
JBrowse link
G CTNNB1 catenin beta 1 multiple interactions EXP ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of and results in decreased phosphorylation of CTNNB1 protein]; Amiodarone results in decreased expression of and results in decreased phosphorylation of CTNNB1 protein; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of TNF protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of and results in decreased phosphorylation of CTNNB1 protein]] CTD PMID:34434487 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096
JBrowse link
G CTSB cathepsin B affects cleavage EXP Amiodarone affects the cleavage of CTSB protein CTD PMID:25881747 NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533
JBrowse link
G CTSD cathepsin D affects cleavage EXP Amiodarone affects the cleavage of CTSD protein CTD PMID:25881747 NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,752...1,764,573
JBrowse link
G CTSL cathepsin L affects cleavage EXP Amiodarone affects the cleavage of CTSL protein CTD PMID:25881747 NCBI chr 9:87,726,119...87,731,469
Ensembl chr 9:87,724,051...87,731,469
JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 multiple interactions ISO Amiodarone inhibits the reaction [Dexamethasone results in increased expression of CXCL2 mRNA] CTD PMID:25900201 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions EXP [Amiodarone co-treated with CYP3A4 protein] results in increased expression of CXCL8 mRNA; [Amiodarone co-treated with CYP3A4 protein] results in increased secretion of CXCL8 protein; Ketoconazole inhibits the reaction [[Amiodarone co-treated with CYP3A4 protein] results in increased expression of CXCL8 mRNA] CTD PMID:22785256 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 increases expression
decreases activity
increases response to substance
multiple interactions
ISO
EXP
Amiodarone results in increased expression of CYP1A1 mRNA
Amiodarone results in decreased activity of CYP1A1 protein
CYP1A1 protein results in increased susceptibility to Amiodarone
Amiodarone promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]
CTD PMID:19224547 PMID:20362646 PMID:26477383 PMID:32084307 PMID:33814510 More... NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 decreases activity
multiple interactions
decreases response to substance
EXP Amiodarone results in decreased activity of CYP1A2 protein
[Amiodarone results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin
CYP1A2 protein results in decreased susceptibility to Amiodarone
CTD PMID:16449812 PMID:26477383 PMID:26599973 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 decreases response to substance
decreases activity
EXP CYP1B1 protein results in decreased susceptibility to Amiodarone
Amiodarone results in decreased activity of CYP1B1 protein
CTD PMID:26477383 PMID:33814510 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902
JBrowse link
G CYP26A1 cytochrome P450 family 26 subfamily A member 1 increases expression EXP Amiodarone results in increased expression of CYP26A1 mRNA CTD PMID:19774075 NCBI chr10:93,073,475...93,077,885
Ensembl chr10:93,073,475...93,077,885
JBrowse link
G CYP2A13 cytochrome P450 family 2 subfamily A member 13 affects expression
increases expression
ISO Amiodarone affects the expression of CYP2A1 mRNA
Amiodarone results in increased expression of CYP2A1 mRNA
CTD PMID:18355885 PMID:19483382 PMID:32084307 NCBI chr19:41,088,451...41,096,195
Ensembl chr19:41,088,451...41,096,195
JBrowse link
G CYP2A6 cytochrome P450 family 2 subfamily A member 6 decreases response to substance EXP CYP2A6 protein results in decreased susceptibility to Amiodarone CTD PMID:26477383 NCBI chr19:40,843,541...40,850,447
Ensembl chr19:40,843,541...40,850,447
JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 affects expression
decreases response to substance
increases expression
ISO
EXP
Amiodarone affects the expression of CYP2B3 mRNA
CYP2B6 protein results in decreased susceptibility to Amiodarone
Amiodarone results in increased expression of CYP2B10 mRNA
CTD PMID:19483382 PMID:24535564 PMID:26477383 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398
JBrowse link
G CYP2C18 cytochrome P450 family 2 subfamily C member 18 decreases response to substance
decreases expression
EXP
ISO
CYP2C18 protein results in decreased susceptibility to Amiodarone
Amiodarone results in decreased expression of CYP2C11 mRNA
CTD PMID:26477383 PMID:32084307 NCBI chr10:94,683,729...94,736,190
Ensembl chr10:94,683,729...94,736,190
JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 decreases response to substance EXP CYP2C19 protein results in decreased susceptibility to Amiodarone CTD PMID:26477383 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547
JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 decreases activity
decreases response to substance
multiple interactions
increases metabolic processing
EXP Amiodarone results in decreased activity of CYP2C8 protein
CYP2C8 protein results in decreased susceptibility to Amiodarone
torsemide inhibits the reaction [Amiodarone results in decreased activity of CYP2C8 protein]
CYP2C8 protein results in increased metabolism of Amiodarone
CTD PMID:15304522 PMID:15716363 PMID:26477383 NCBI chr10:95,036,772...95,069,497
Ensembl chr10:95,036,772...95,069,497
JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 multiple interactions
increases expression
decreases response to substance
decreases activity
EXP [Amiodarone results in decreased activity of CYP2C9 protein] which results in decreased chemical synthesis of 16-O-demethylaconitine; [Amiodarone results in decreased activity of CYP2C9 protein] which results in decreased chemical synthesis of Aconitine metabolite; Amiodarone inhibits the reaction [CYP2C9 protein affects the metabolism of Diclofenac]; Amiodarone promotes the reaction [CYP2C9 protein affects the metabolism of Naproxen]; Amiodarone promotes the reaction [CYP2C9 protein results in increased metabolism of Coumarins]
Amiodarone results in increased expression of CYP2C9 mRNA
CYP2C9 protein results in decreased susceptibility to Amiodarone
CTD PMID:14557374 PMID:16081671 PMID:16449812 PMID:21277363 PMID:26477383 More... NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091
JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 (gene/pseudogene) decreases activity
affects expression
multiple interactions
increases expression
EXP
ISO
Amiodarone results in decreased activity of CYP2D6 protein
Amiodarone affects the expression of CYP2D4 mRNA
CYP2D6 gene polymorphism affects the reaction [Amiodarone results in increased abundance of Metoprolol]
Amiodarone results in increased expression of CYP2D6 mRNA
CTD PMID:15541258 PMID:16449812 PMID:19483382 PMID:19774075 NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,865
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 decreases response to substance EXP CYP2E1 protein results in decreased susceptibility to Amiodarone CTD PMID:26477383 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
JBrowse link
G CYP2F1 cytochrome P450 family 2 subfamily F member 1 affects expression ISO Amiodarone affects the expression of CYP2F4 mRNA CTD PMID:19483382 NCBI chr19:41,114,432...41,128,381
Ensembl chr19:41,114,432...41,128,381
JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 increases expression
affects expression
EXP
ISO
Amiodarone results in increased expression of CYP2J2 mRNA
Amiodarone affects the expression of CYP2J4 mRNA
CTD PMID:19483382 PMID:19774075 NCBI chr 1:59,893,308...59,969,212
Ensembl chr 1:59,893,308...59,926,773
JBrowse link
G CYP2R1 cytochrome P450 family 2 subfamily R member 1 increases expression EXP Amiodarone results in increased expression of CYP2R1 mRNA CTD PMID:19774075 NCBI chr11:14,877,440...14,892,443
Ensembl chr11:14,877,440...14,892,231
JBrowse link
G CYP2U1 cytochrome P450 family 2 subfamily U member 1 decreases expression ISO Amiodarone results in decreased expression of CYP2U1 mRNA CTD PMID:24535564 NCBI chr 4:107,931,549...107,953,461
Ensembl chr 4:107,931,549...107,953,461
JBrowse link
G CYP39A1 cytochrome P450 family 39 subfamily A member 1 decreases expression ISO Amiodarone results in decreased expression of CYP39A1 mRNA CTD PMID:24535564 NCBI chr 6:46,549,580...46,652,818
Ensembl chr 6:46,549,580...46,652,830
JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 decreases ethylation
increases degradation
increases expression
increases response to substance
increases metabolic processing
decreases activity
multiple interactions
EXP
ISO
CYP3A4 protein results in decreased ethylation of Amiodarone
CYP3A4 protein results in increased degradation of Amiodarone
Amiodarone results in increased expression of CYP3A4 mRNA
CYP3A4 protein results in increased susceptibility to Amiodarone
CYP3A4 protein results in increased metabolism of Amiodarone
Amiodarone results in decreased activity of CYP3A4 protein
[Amiodarone co-treated with Benzoic Acid co-treated with cyproconazole co-treated with flusilazole co-treated with enilconazole co-treated with prochloraz co-treated with propiconazole co-treated with tebuconazole] results in increased expression of CYP3A4 protein; [Amiodarone co-treated with CYP3A4 protein] results in increased expression of CD86 protein; [Amiodarone co-treated with CYP3A4 protein] results in increased expression of CXCL8 mRNA; [Amiodarone co-treated with CYP3A4 protein] results in increased expression of ICAM1 protein; [Amiodarone co-treated with CYP3A4 protein] results in increased expression of TNF mRNA; [Amiodarone co-treated with CYP3A4 protein] results in increased secretion of CXCL8 protein; [Amiodarone co-treated with CYP3A4 protein] results in increased secretion of TNF protein; [CYP3A4 protein results in increased metabolism of Amiodarone] which results in increased abundance of mono-N-desethylamiodarone; Amiodarone inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]; Amiodarone inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Testosterone]; Amiodarone inhibits the reaction [CYP3A4 protein results in increased oxidation of 7-benzyloxy-4-trifluoromethylcoumarin]; Ketoconazole inhibits the reaction [[Amiodarone co-treated with CYP3A4 protein] results in increased expression of CXCL8 mRNA]; Ketoconazole inhibits the reaction [[Amiodarone co-treated with CYP3A4 protein] results in increased expression of TNF mRNA]; Metronidazole inhibits the reaction [CYP3A4 protein results in increased metabolism of Amiodarone]
CTD PMID:7905403 PMID:8445979 PMID:15304522 PMID:15869686 PMID:16449812 More... NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 affects expression
decreases response to substance
ISO
EXP
Amiodarone affects the expression of CYP3A9 mRNA
CYP3A5 protein results in decreased susceptibility to Amiodarone
CTD PMID:19483382 PMID:26477383 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996
JBrowse link
G CYP3A7 cytochrome P450 family 3 subfamily A member 7 decreases response to substance EXP CYP3A7 protein results in decreased susceptibility to Amiodarone CTD PMID:26477383 NCBI chr 7:99,705,036...99,735,196
Ensembl chr 7:99,705,036...99,735,196
JBrowse link
G CYP4A22 cytochrome P450 family 4 subfamily A member 22 increases expression ISO Amiodarone results in increased expression of CYP4A1 mRNA
Amiodarone results in increased expression of CYP4A31 mRNA
CTD PMID:12883083 PMID:24535564 NCBI chr 1:47,137,441...47,149,727
Ensembl chr 1:47,137,435...47,149,727
JBrowse link
G CYP4F8 cytochrome P450 family 4 subfamily F member 8 affects expression ISO Amiodarone affects the expression of CYP4F6 mRNA CTD PMID:19483382 NCBI chr19:15,615,218...15,630,639
Ensembl chr19:15,615,218...15,630,639
JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 decreases expression
increases expression
ISO Amiodarone results in decreased expression of CYP7A1 mRNA
Amiodarone results in increased expression of CYP7A1 mRNA
CTD PMID:19224547 PMID:22291062 NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163
JBrowse link
G CYP7B1 cytochrome P450 family 7 subfamily B member 1 decreases expression ISO Amiodarone results in decreased expression of CYP7B1 mRNA CTD PMID:24535564 NCBI chr 8:64,586,575...64,798,737
Ensembl chr 8:64,587,763...64,798,737
JBrowse link
G DACT1 dishevelled binding antagonist of beta catenin 1 decreases expression ISO Amiodarone results in decreased expression of DACT1 mRNA CTD PMID:24535564 NCBI chr14:58,634,061...58,648,321
Ensembl chr14:58,633,967...58,648,321
JBrowse link
G DAPK2 death associated protein kinase 2 increases expression EXP Amiodarone results in increased expression of DAPK2 mRNA CTD PMID:19774075 NCBI chr15:63,907,036...64,046,485
Ensembl chr15:63,907,036...64,072,033
JBrowse link
G DBI diazepam binding inhibitor, acyl-CoA binding protein affects expression ISO Amiodarone affects the expression of DBI mRNA CTD PMID:19483382 NCBI chr 2:119,366,977...119,372,543
Ensembl chr 2:119,366,924...119,372,550
JBrowse link
G DBN1 drebrin 1 increases expression EXP Amiodarone results in increased expression of DBN1 mRNA CTD PMID:19774075 NCBI chr 5:177,456,610...177,473,634
Ensembl chr 5:177,456,608...177,474,401
JBrowse link
G DBNDD1 dysbindin domain containing 1 increases expression EXP Amiodarone results in increased expression of DBNDD1 mRNA CTD PMID:19774075 NCBI chr16:90,004,871...90,019,890
Ensembl chr16:90,004,871...90,019,890
JBrowse link
G DCAF11 DDB1 and CUL4 associated factor 11 affects expression ISO Amiodarone affects the expression of DCAF11 mRNA CTD PMID:19483382 NCBI chr14:24,114,777...24,125,242
Ensembl chr14:24,114,195...24,125,242
JBrowse link
G DCAF8 DDB1 and CUL4 associated factor 8 affects expression ISO Amiodarone affects the expression of DCAF8 mRNA CTD PMID:18355885 NCBI chr 1:160,215,720...160,262,549
Ensembl chr 1:160,215,715...160,262,549
JBrowse link
G DCST2 DC-STAMP domain containing 2 increases expression EXP Amiodarone results in increased expression of DCST2 mRNA CTD PMID:19774075 NCBI chr 1:155,018,527...155,033,781
Ensembl chr 1:155,018,520...155,033,781
JBrowse link
G DCTN1 dynactin subunit 1 increases expression EXP Amiodarone results in increased expression of DCTN1 mRNA CTD PMID:19774075 NCBI chr 2:74,361,155...74,391,866
Ensembl chr 2:74,361,154...74,392,087
JBrowse link
G DCXR dicarbonyl and L-xylulose reductase affects expression ISO Amiodarone affects the expression of DCXR mRNA CTD PMID:19483382 NCBI chr17:82,035,858...82,037,697
Ensembl chr17:82,035,136...82,037,709
JBrowse link
G DDC dopa decarboxylase increases expression ISO Amiodarone results in increased expression of DDC mRNA CTD PMID:24489787 NCBI chr 7:50,458,442...50,565,405
Ensembl chr 7:50,458,436...50,565,405
JBrowse link
G DDIT3 DNA damage inducible transcript 3 increases expression
decreases response to substance
multiple interactions
EXP
ISO
[Amiodarone results in increased expression of DDIT3 mRNA] which results in increased expression of TNFRSF10B mRNA; [Amiodarone results in increased expression of DDIT3 protein] which results in increased expression of TNFRSF10B protein; Amiodarone results in increased expression of DDIT3 mRNA; Amiodarone results in increased expression of DDIT3 protein
DDIT3 gene mutant form results in decreased susceptibility to Amiodarone
1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of DDIT3 mRNA]; Amiodarone results in increased expression of and affects the localization of DDIT3 protein; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of CIDEA mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of CIDEC mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of CIDEC protein]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of DNAJB9 mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased splicing of XBP1 mRNA]
4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased expression of DDIT3 mRNA]; 4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased expression of DDIT3 protein]; DDIT3 mutant form inhibits the reaction [Amiodarone results in increased expression of TNFRSF10B]; Egtazic Acid inhibits the reaction [Amiodarone results in increased expression of DDIT3]
CTD PMID:19774075 PMID:21292685 PMID:25295624 PMID:28962527 PMID:32651653 More... NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
JBrowse link
G DDIT4 DNA damage inducible transcript 4 increases expression EXP Amiodarone results in increased expression of DDIT4 mRNA CTD PMID:19774075 NCBI chr10:72,273,924...72,276,036
Ensembl chr10:72,273,919...72,276,036
JBrowse link
G DDX17 DEAD-box helicase 17 increases expression EXP Amiodarone results in increased expression of DDX17 mRNA CTD PMID:19774075 NCBI chr22:38,483,438...38,506,311
Ensembl chr22:38,483,438...38,507,660
JBrowse link
G DDX31 DEAD-box helicase 31 increases expression EXP Amiodarone results in increased expression of DDX31 mRNA CTD PMID:19774075 NCBI chr 9:132,592,997...132,669,983
Ensembl chr 9:132,592,997...132,670,401
JBrowse link
G DDX39A DExD-box helicase 39A increases expression EXP Amiodarone results in increased expression of DDX39A mRNA CTD PMID:19774075 NCBI chr19:14,408,798...14,419,383
Ensembl chr19:14,408,798...14,419,383
JBrowse link
G DDX49 DEAD-box helicase 49 increases expression EXP Amiodarone results in increased expression of DDX49 mRNA CTD PMID:19774075 NCBI chr19:18,919,715...18,928,630
Ensembl chr19:18,919,705...18,929,189
JBrowse link
G DECR1 2,4-dienoyl-CoA reductase 1 affects expression ISO Amiodarone affects the expression of DECR1 mRNA CTD PMID:19483382 NCBI chr 8:90,001,477...90,053,633
Ensembl chr 8:90,001,405...90,053,633
JBrowse link
G DEDD death effector domain containing increases expression EXP Amiodarone results in increased expression of DEDD mRNA CTD PMID:19774075 NCBI chr 1:161,120,974...161,132,667
Ensembl chr 1:161,120,974...161,132,688
JBrowse link
G DEPP1 DEPP autophagy regulator 1 increases expression EXP Amiodarone results in increased expression of DEPP1 mRNA CTD PMID:17175557 NCBI chr10:44,976,128...44,978,809
Ensembl chr10:44,970,981...44,978,809
JBrowse link
G DEPTOR DEP domain containing MTOR interacting protein increases expression EXP Amiodarone results in increased expression of DEPTOR mRNA CTD PMID:19774075 NCBI chr 8:119,873,722...120,050,918
Ensembl chr 8:119,873,717...120,050,918
JBrowse link
G DEXI Dexi homolog affects expression ISO Amiodarone affects the expression of DEXI mRNA CTD PMID:19483382 NCBI chr16:10,928,891...10,942,468
Ensembl chr16:10,928,891...10,942,468
JBrowse link
G DGAT1 diacylglycerol O-acyltransferase 1 affects expression
increases expression
ISO
EXP
Amiodarone affects the expression of DGAT1 mRNA
Amiodarone results in increased expression of DGAT1 mRNA
CTD PMID:19483382 PMID:32651653 NCBI chr 8:144,314,584...144,326,852
Ensembl chr 8:144,314,584...144,326,910
JBrowse link
G DGAT2 diacylglycerol O-acyltransferase 2 decreases expression ISO Amiodarone results in decreased expression of DGAT2 mRNA CTD PMID:28962527 NCBI chr11:75,768,778...75,801,534
Ensembl chr11:75,759,512...75,801,535
JBrowse link
G DHCR24 24-dehydrocholesterol reductase affects expression ISO Amiodarone affects the expression of DHCR24 mRNA CTD PMID:19483382 NCBI chr 1:54,849,627...54,887,195
Ensembl chr 1:54,849,627...54,887,195
JBrowse link
G DHCR7 7-dehydrocholesterol reductase increases expression ISO Amiodarone results in increased expression of DHCR7 mRNA CTD PMID:22291062 NCBI chr11:71,427,287...71,449,043
Ensembl chr11:71,428,193...71,452,868
JBrowse link
G DHRS2 dehydrogenase/reductase 2 increases expression EXP Amiodarone results in increased expression of DHRS2 mRNA CTD PMID:19774075 NCBI chr14:23,630,115...23,645,639
Ensembl chr14:23,630,115...23,645,639
JBrowse link
G DHRS4 dehydrogenase/reductase 4 affects expression ISO Amiodarone affects the expression of DHRS4 mRNA CTD PMID:19483382 NCBI chr14:23,953,770...23,969,279
Ensembl chr14:23,953,734...23,969,279
JBrowse link
G DHRS7B dehydrogenase/reductase 7B affects expression ISO Amiodarone affects the expression of DHRS7B mRNA CTD PMID:19483382 NCBI chr17:21,126,964...21,191,420
Ensembl chr17:21,123,364...21,193,265
JBrowse link
G DHX16 DEAH-box helicase 16 affects expression ISO Amiodarone affects the expression of DHX16 mRNA CTD PMID:19483382 NCBI chr 6:30,653,127...30,673,006
Ensembl chr 6:30,653,119...30,673,006
JBrowse link
G DHX57 DExH-box helicase 57 increases expression EXP Amiodarone results in increased expression of DHX57 mRNA CTD PMID:19774075 NCBI chr 2:38,797,729...38,875,934
Ensembl chr 2:38,797,729...38,875,934
JBrowse link
G DIO1 iodothyronine deiodinase 1 decreases activity ISO
EXP
Amiodarone results in decreased activity of DIO1 protein CTD PMID:12538616 PMID:16131326 NCBI chr 1:53,894,187...53,911,086
Ensembl chr 1:53,891,239...53,911,086
JBrowse link
G DLG4 discs large MAGUK scaffold protein 4 increases expression EXP Amiodarone results in increased expression of DLG4 mRNA CTD PMID:19774075 NCBI chr17:7,187,187...7,220,050
Ensembl chr17:7,187,187...7,219,836
JBrowse link
G DLK2 delta like non-canonical Notch ligand 2 increases expression EXP Amiodarone results in increased expression of DLK2 mRNA CTD PMID:19774075 NCBI chr 6:43,450,352...43,456,632
Ensembl chr 6:43,450,352...43,456,632
JBrowse link
G DMAC2L distal membrane arm assembly component 2 like affects expression ISO Amiodarone affects the expression of DMAC2L mRNA CTD PMID:19483382 NCBI chr14:50,311,516...50,327,957
Ensembl chr14:50,312,324...50,335,558
JBrowse link
G DNAAF3 dynein axonemal assembly factor 3 increases expression EXP Amiodarone results in increased expression of DNAAF3 mRNA CTD PMID:19774075 NCBI chr19:55,158,661...55,166,722
Ensembl chr19:55,158,661...55,166,722
JBrowse link
G DNAH7 dynein axonemal heavy chain 7 increases expression EXP Amiodarone results in increased expression of DNAH7 mRNA CTD PMID:19774075 NCBI chr 2:195,737,703...196,068,837
Ensembl chr 2:195,737,703...196,068,837
JBrowse link
G DNAJB11 DnaJ heat shock protein family (Hsp40) member B11 decreases expression ISO Amiodarone results in decreased expression of DNAJB11 mRNA CTD PMID:24535564 NCBI chr 3:186,570,720...186,585,793
Ensembl chr 3:186,567,403...186,585,800
JBrowse link
G DNAJB12 DnaJ heat shock protein family (Hsp40) member B12 increases expression EXP Amiodarone results in increased expression of DNAJB12 mRNA CTD PMID:19774075 NCBI chr10:72,332,863...72,354,919
Ensembl chr10:72,332,830...72,355,149
JBrowse link
G DNAJB7 DnaJ heat shock protein family (Hsp40) member B7 increases expression EXP Amiodarone results in increased expression of DNAJB7 mRNA CTD PMID:19774075 NCBI chr22:40,859,549...40,862,113
Ensembl chr22:40,859,549...40,862,113
JBrowse link
G DNAJB9 DnaJ heat shock protein family (Hsp40) member B9 increases expression
multiple interactions
EXP
ISO
Amiodarone results in increased expression of DNAJB9 mRNA
Amiodarone results in increased expression of DNAJB9 mRNA; Amiodarone results in increased expression of DNAJB9 protein
1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of DNAJB9 mRNA]; 4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased expression of DNAJB9 mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of DNAJB9 mRNA]
CTD PMID:19774075 PMID:28962527 PMID:34259586 PMID:36586010 NCBI chr 7:108,569,874...108,574,850
Ensembl chr 7:108,569,867...108,574,850
JBrowse link
G DNAJC3 DnaJ heat shock protein family (Hsp40) member C3 affects expression
multiple interactions
increases expression
ISO Amiodarone affects the expression of DNAJC3 mRNA
1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of DNAJC3 mRNA]
CTD PMID:19483382 PMID:28962527 PMID:34259586 NCBI chr13:95,677,139...95,794,988
Ensembl chr13:95,677,139...95,794,988
JBrowse link
G DNASE1 deoxyribonuclease 1 increases expression EXP Amiodarone results in increased expression of DNASE1 mRNA CTD PMID:19774075 NCBI chr16:3,611,760...3,665,461
Ensembl chr16:3,611,728...3,680,143
JBrowse link
G DOCK5 dedicator of cytokinesis 5 increases expression EXP Amiodarone results in increased expression of DOCK5 mRNA CTD PMID:19774075 NCBI chr 8:25,184,689...25,415,711
Ensembl chr 8:25,184,689...25,418,082
JBrowse link
G DPM2 dolichyl-phosphate mannosyltransferase subunit 2, regulatory increases expression EXP Amiodarone results in increased expression of DPM2 mRNA CTD PMID:19774075 NCBI chr 9:127,935,099...127,937,854
Ensembl chr 9:127,935,099...127,937,854
JBrowse link
G DPP4 dipeptidyl peptidase 4 affects expression ISO Amiodarone affects the expression of DPP4 mRNA CTD PMID:19483382 NCBI chr 2:161,992,245...162,074,215
Ensembl chr 2:161,992,245...162,074,394
JBrowse link
G DPYD dihydropyrimidine dehydrogenase affects expression ISO Amiodarone affects the expression of DPYD mRNA CTD PMID:19483382 NCBI chr 1:97,077,743...97,921,059
Ensembl chr 1:97,077,743...97,995,000
JBrowse link
G DRC7 dynein regulatory complex subunit 7 increases expression EXP Amiodarone results in increased expression of DRC7 mRNA CTD PMID:19774075 NCBI chr16:57,694,806...57,731,805
Ensembl chr16:57,694,793...57,731,805
JBrowse link
G DUSP1 dual specificity phosphatase 1 increases expression EXP Amiodarone results in increased expression of DUSP1 mRNA CTD PMID:19774075 NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195
JBrowse link
G DUSP10 dual specificity phosphatase 10 increases expression EXP Amiodarone results in increased expression of DUSP10 mRNA CTD PMID:19774075 NCBI chr 1:221,701,424...221,742,089
Ensembl chr 1:221,701,424...221,742,089
JBrowse link
G DUT deoxyuridine triphosphatase increases expression EXP Amiodarone results in increased expression of DUT mRNA CTD PMID:19774075 NCBI chr15:48,331,095...48,343,373
Ensembl chr15:48,331,011...48,343,373
JBrowse link
G EAF2 ELL associated factor 2 increases expression EXP Amiodarone results in increased expression of EAF2 mRNA CTD PMID:19774075 NCBI chr 3:121,835,209...121,886,526
Ensembl chr 3:121,835,183...121,886,526
JBrowse link
G EARS2 glutamyl-tRNA synthetase 2, mitochondrial affects expression ISO Amiodarone affects the expression of EARS2 mRNA CTD PMID:19483382 NCBI chr16:23,520,754...23,557,375
Ensembl chr16:23,520,754...23,557,731
JBrowse link
G EBP EBP cholestenol delta-isomerase increases expression ISO Amiodarone results in increased expression of EBP mRNA CTD PMID:22291062 NCBI chr  X:48,521,808...48,528,716
Ensembl chr  X:48,521,799...48,528,716
JBrowse link
G ECH1 enoyl-CoA hydratase 1 increases expression ISO Amiodarone results in increased expression of ECH1 mRNA CTD PMID:24535564 NCBI chr19:38,815,422...38,831,794
Ensembl chr19:38,815,422...38,831,841
JBrowse link
G ECHS1 enoyl-CoA hydratase, short chain 1 affects expression ISO Amiodarone affects the expression of ECHS1 mRNA CTD PMID:19483382 NCBI chr10:133,362,485...133,373,354
Ensembl chr10:133,362,485...133,373,354
JBrowse link
G ECI1 enoyl-CoA delta isomerase 1 affects expression ISO Amiodarone affects the expression of ECI1 mRNA CTD PMID:19483382 NCBI chr16:2,239,402...2,251,587
Ensembl chr16:2,239,402...2,252,300
JBrowse link
G ECI2 enoyl-CoA delta isomerase 2 affects expression ISO Amiodarone affects the expression of ECI2 mRNA CTD PMID:19483382 NCBI chr 6:4,115,706...4,135,575
Ensembl chr 6:4,115,693...4,135,597
JBrowse link
G ECPAS Ecm29 proteasome adaptor and scaffold decreases expression ISO Amiodarone results in decreased expression of ECPAS mRNA CTD PMID:17991464 NCBI chr 9:111,360,685...111,484,383
Ensembl chr 9:111,360,685...111,484,745
JBrowse link
G EED embryonic ectoderm development increases expression EXP Amiodarone results in increased expression of EED mRNA CTD PMID:19774075 NCBI chr11:86,244,753...86,287,615
Ensembl chr11:86,201,212...86,279,807
JBrowse link
G EEF1G eukaryotic translation elongation factor 1 gamma affects expression ISO Amiodarone affects the expression of EEF1G mRNA CTD PMID:19483382 NCBI chr11:62,559,596...62,573,891
Ensembl chr11:62,559,596...62,574,086
JBrowse link
G EEPD1 endonuclease/exonuclease/phosphatase family domain containing 1 increases expression EXP Amiodarone results in increased expression of EEPD1 mRNA CTD PMID:19774075 NCBI chr 7:36,153,254...36,301,538
Ensembl chr 7:36,153,254...36,301,538
JBrowse link
G EFCAB5 EF-hand calcium binding domain 5 increases expression EXP Amiodarone results in increased expression of EFCAB5 mRNA CTD PMID:19774075 NCBI chr17:29,929,903...30,108,452
Ensembl chr17:29,929,200...30,108,452
JBrowse link
G EFCC1 EF-hand and coiled-coil domain containing 1 increases expression EXP Amiodarone results in increased expression of EFCC1 mRNA CTD PMID:19774075 NCBI chr 3:129,001,304...129,040,742
Ensembl chr 3:129,001,304...129,040,742
JBrowse link
G EGF epidermal growth factor multiple interactions EXP Amiodarone inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; RTKI cpd promotes the reaction [Amiodarone inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]] CTD PMID:26515726 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766
JBrowse link
G EGFL6 EGF like domain multiple 6 increases expression EXP Amiodarone results in increased expression of EGFL6 mRNA CTD PMID:19774075 NCBI chr  X:13,569,601...13,633,575
Ensembl chr  X:13,569,601...13,633,575
JBrowse link
G EGFR epidermal growth factor receptor decreases expression
multiple interactions
decreases phosphorylation
ISO
EXP
Amiodarone results in decreased expression of EGFR mRNA
Amiodarone affects the reaction [VCAN protein alternative form affects the phosphorylation of EGFR protein]
Amiodarone results in decreased phosphorylation of EGFR protein
Amiodarone inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; RTKI cpd promotes the reaction [Amiodarone inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]]
CTD PMID:24535564 PMID:26515726 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
JBrowse link
G EGR1 early growth response 1 increases expression EXP Amiodarone results in increased expression of EGR1 mRNA CTD PMID:19774075 PMID:36586010 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
JBrowse link
G EGR2 early growth response 2 increases expression EXP Amiodarone results in increased expression of EGR2 mRNA CTD PMID:19774075 NCBI chr10:62,811,996...62,819,167
Ensembl chr10:62,811,996...62,819,167
JBrowse link
G EHHADH enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase affects expression
decreases expression
increases expression
ISO
EXP
Amiodarone affects the expression of EHHADH mRNA
Amiodarone results in decreased expression of EHHADH mRNA
Amiodarone results in increased expression of EHHADH mRNA
CTD PMID:15265979 PMID:19483382 PMID:24489787 PMID:24535564 PMID:27089845 NCBI chr 3:185,190,624...185,254,049
Ensembl chr 3:185,190,624...185,281,990
JBrowse link
G EHMT1 euchromatic histone lysine methyltransferase 1 increases expression EXP Amiodarone results in increased expression of EHMT1 mRNA CTD PMID:19774075 NCBI chr 9:137,619,005...137,836,127
Ensembl chr 9:137,618,992...137,870,016
JBrowse link
G EIF2A eukaryotic translation initiation factor 2A increases phosphorylation EXP
ISO
Amiodarone results in increased phosphorylation of EIF2A protein CTD PMID:21292685 PMID:28962527 NCBI chr 3:150,546,787...150,586,016
Ensembl chr 3:150,546,678...150,586,016
JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 increases expression EXP Amiodarone results in increased expression of EIF2AK3 mRNA CTD PMID:19774075 NCBI chr 2:88,556,741...88,628,145
Ensembl chr 2:88,556,741...88,691,518
JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation
multiple interactions
EXP
ISO
Amiodarone results in increased phosphorylation of EIF2S1 protein
4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased phosphorylation of EIF2S1 protein]
CTD PMID:25295624 PMID:32651653 PMID:34259586 NCBI chr14:67,360,328...67,386,516
Ensembl chr14:67,360,328...67,386,516
JBrowse link
G EIF4A2 eukaryotic translation initiation factor 4A2 affects expression ISO Amiodarone affects the expression of EIF4A2 mRNA CTD PMID:19483382 NCBI chr 3:186,783,577...186,789,897
Ensembl chr 3:186,783,205...186,789,897
JBrowse link
G EIF4B eukaryotic translation initiation factor 4B affects expression ISO Amiodarone affects the expression of EIF4B mRNA CTD PMID:18355885 NCBI chr12:53,006,456...53,042,215
Ensembl chr12:53,006,282...53,042,215
JBrowse link
G EIF4E eukaryotic translation initiation factor 4E multiple interactions EXP Amiodarone promotes the reaction [EIF4E protein binds to EIF4EBP1 protein] CTD PMID:19771169 NCBI chr 4:98,879,276...98,929,133
Ensembl chr 4:98,879,276...98,929,133
JBrowse link
G EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions
decreases phosphorylation
affects expression
EXP
ISO
Amiodarone inhibits the reaction [MTOR protein results in increased phosphorylation of EIF4EBP1 protein]; Amiodarone promotes the reaction [EIF4E protein binds to EIF4EBP1 protein]
Amiodarone results in decreased phosphorylation of EIF4EBP1 protein
Amiodarone affects the expression of EIF4EBP1 mRNA
CTD PMID:19483382 PMID:19771169 PMID:23912912 NCBI chr 8:38,030,534...38,060,365
Ensembl chr 8:38,030,534...38,060,365
JBrowse link
G EIF4H eukaryotic translation initiation factor 4H affects expression ISO Amiodarone affects the expression of EIF4H mRNA CTD PMID:19483382 NCBI chr 7:74,174,356...74,197,096
Ensembl chr 7:74,174,231...74,197,122
JBrowse link
G EIF5 eukaryotic translation initiation factor 5 increases expression EXP Amiodarone results in increased expression of EIF5 mRNA CTD PMID:19774075 NCBI chr14:103,334,237...103,345,025
Ensembl chr14:103,333,544...103,345,025
JBrowse link
G ELMO3 engulfment and cell motility 3 increases expression EXP Amiodarone results in increased expression of ELMO3 mRNA CTD PMID:19774075 NCBI chr16:67,199,131...67,204,004
Ensembl chr16:67,199,111...67,204,029
JBrowse link
G ELOVL6 ELOVL fatty acid elongase 6 increases expression
decreases expression
ISO
EXP
Amiodarone results in increased expression of ELOVL6 mRNA
Amiodarone results in decreased expression of ELOVL6 mRNA; Amiodarone results in decreased expression of ELOVL6 protein
CTD PMID:24489787 PMID:29248575 PMID:34259586 NCBI chr 4:110,045,846...110,199,202
Ensembl chr 4:110,045,846...110,199,199
JBrowse link
G ELP1 elongator acetyltransferase complex subunit 1 increases expression EXP Amiodarone results in increased expression of ELP1 mRNA CTD PMID:19774075 NCBI chr 9:108,867,517...108,934,124
Ensembl chr 9:108,866,898...108,934,328
JBrowse link
G ENC1 ectodermal-neural cortex 1 affects expression ISO Amiodarone affects the expression of ENC1 mRNA CTD PMID:19483382 NCBI chr 5:74,627,409...74,640,728
Ensembl chr 5:74,627,406...74,641,424
JBrowse link
G ENHO energy homeostasis associated decreases expression ISO Amiodarone results in decreased expression of ENHO mRNA CTD PMID:24535564 NCBI chr 9:34,521,043...34,522,990
Ensembl chr 9:34,521,043...34,522,990
JBrowse link
G ENO1 enolase 1 affects expression ISO Amiodarone affects the expression of ENO1 mRNA CTD PMID:19483382 NCBI chr 1:8,861,000...8,878,686
Ensembl chr 1:8,861,000...8,879,190
JBrowse link
G ENPEP glutamyl aminopeptidase affects expression ISO Amiodarone affects the expression of ENPEP mRNA CTD PMID:19483382 NCBI chr 4:110,476,155...110,565,285
Ensembl chr 4:110,365,733...110,565,285
JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 affects expression ISO Amiodarone affects the expression of ENPP1 mRNA CTD PMID:19483382 NCBI chr 6:131,808,020...131,895,155
Ensembl chr 6:131,808,016...131,895,155
JBrowse link
G ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 increases expression EXP Amiodarone results in increased expression of ENPP7 mRNA CTD PMID:19774075 NCBI chr17:79,730,943...79,742,219
Ensembl chr17:79,730,943...79,742,219
JBrowse link
G EPC1 enhancer of polycomb homolog 1 increases expression EXP Amiodarone results in increased expression of EPC1 mRNA CTD PMID:19774075 NCBI chr10:32,267,751...32,378,769
Ensembl chr10:32,267,751...32,378,798
JBrowse link
G EPC2 enhancer of polycomb homolog 2 increases expression EXP Amiodarone results in increased expression of EPC2 mRNA CTD PMID:19774075 NCBI chr 2:148,644,751...148,787,569
Ensembl chr 2:148,644,440...148,788,495
JBrowse link
G EPCAM epithelial cell adhesion molecule affects expression ISO Amiodarone affects the expression of EPCAM mRNA CTD PMID:19483382 NCBI chr 2:47,369,311...47,387,020
Ensembl chr 2:47,345,158...47,387,601
JBrowse link
G EPHX1 epoxide hydrolase 1 affects expression ISO Amiodarone affects the expression of EPHX1 mRNA CTD PMID:18355885 NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,124...225,845,563
JBrowse link
G ERI2 ERI1 exoribonuclease family member 2 increases expression EXP Amiodarone results in increased expression of ERI2 mRNA CTD PMID:19774075 NCBI chr16:20,780,193...20,806,472
Ensembl chr16:20,780,193...20,900,349
JBrowse link
G ERMN ermin increases expression EXP Amiodarone results in increased expression of ERMN mRNA CTD PMID:19774075 NCBI chr 2:157,318,631...157,327,712
Ensembl chr 2:157,318,631...157,327,713
JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 increases phosphorylation ISO
EXP
Amiodarone results in increased phosphorylation of ERN1 protein CTD PMID:28962527 PMID:32651653 PMID:34259586 NCBI chr17:64,039,142...64,130,144
Ensembl chr17:64,039,080...64,130,819
JBrowse link
G ERO1B endoplasmic reticulum oxidoreductase 1 beta decreases expression ISO Amiodarone results in decreased expression of ERO1B mRNA CTD PMID:24535564 NCBI chr 1:236,215,101...236,281,958
Ensembl chr 1:236,214,681...236,282,019
JBrowse link
G ERP29 endoplasmic reticulum protein 29 affects expression ISO Amiodarone affects the expression of ERP29 mRNA CTD PMID:18355885 PMID:19483382 NCBI chr12:112,013,426...112,023,449
Ensembl chr12:112,013,348...112,023,449
JBrowse link
G ESD esterase D affects expression ISO Amiodarone affects the expression of ESD mRNA CTD PMID:19483382 NCBI chr13:46,771,256...46,797,700
Ensembl chr13:46,771,256...46,797,420
JBrowse link
G ETFB electron transfer flavoprotein subunit beta affects expression ISO Amiodarone affects the expression of ETFB mRNA CTD PMID:19483382 NCBI chr19:51,345,155...51,366,388
Ensembl chr19:51,345,169...51,366,388
JBrowse link
G ETFDH electron transfer flavoprotein dehydrogenase increases expression ISO Amiodarone results in increased expression of ETFDH mRNA CTD PMID:24489787 NCBI chr 4:158,672,296...158,709,623
Ensembl chr 4:158,671,968...158,710,742
JBrowse link
G ETV7 ETS variant transcription factor 7 increases expression EXP Amiodarone results in increased expression of ETV7 mRNA CTD PMID:19774075 NCBI chr 6:36,354,088...36,387,669
Ensembl chr 6:36,354,091...36,387,800
JBrowse link
G EXO1 exonuclease 1 increases expression EXP Amiodarone results in increased expression of EXO1 mRNA CTD PMID:19774075 NCBI chr 1:241,847,986...241,889,939
Ensembl chr 1:241,847,967...241,895,148
JBrowse link
G F11 coagulation factor XI decreases expression ISO Amiodarone results in decreased expression of F11 mRNA CTD PMID:24535564 NCBI chr 4:186,266,189...186,289,681
Ensembl chr 4:186,266,189...186,289,681
JBrowse link
G F2 coagulation factor II, thrombin multiple interactions EXP Amiodarone inhibits the reaction [F2 protein results in increased expression of and results in increased activity of F3 protein] CTD PMID:18974383 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions
decreases activity
EXP
ISO
Amiodarone inhibits the reaction [F2 protein results in increased expression of and results in increased activity of F3 protein]; Amiodarone inhibits the reaction [TNF protein results in increased expression of and results in increased activity of F3 protein]; Amiodarone inhibits the reaction [TNF protein results in increased expression of F3 mRNA]; Amiodarone inhibits the reaction [TNF protein results in increased expression of F3 protein]
Amiodarone results in decreased activity of F3 protein
CTD PMID:18974383 PMID:23305835 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
JBrowse link
G FAAH fatty acid amide hydrolase affects expression ISO Amiodarone affects the expression of FAAH mRNA CTD PMID:19483382 NCBI chr 1:46,394,317...46,413,845
Ensembl chr 1:46,394,317...46,413,848
JBrowse link
G FABP1 fatty acid binding protein 1 increases expression
decreases expression
EXP
ISO
Amiodarone results in increased expression of FABP1 mRNA
Amiodarone results in decreased expression of FABP1 mRNA
CTD PMID:15342952 PMID:17567588 PMID:28962527 NCBI chr 2:88,122,982...88,128,062
Ensembl chr 2:88,122,982...88,128,062
JBrowse link
G FABP4 fatty acid binding protein 4 increases expression ISO Amiodarone results in increased expression of FABP4 mRNA CTD PMID:34259586 NCBI chr 8:81,478,419...81,483,233
Ensembl chr 8:81,478,419...81,483,236
JBrowse link
G FADS1 fatty acid desaturase 1 increases expression ISO Amiodarone results in increased expression of FADS1 mRNA CTD PMID:19224547 PMID:22291062 NCBI chr11:61,799,627...61,817,003
Ensembl chr11:61,799,627...61,829,318
JBrowse link
G FADS2 fatty acid desaturase 2 multiple interactions
affects expression
increases expression
EXP
ISO
[2-chloro-5-nitrobenzanilide results in decreased activity of PPARG protein] inhibits the reaction [Amiodarone results in increased expression of FADS2 mRNA]; FADS2 protein affects the reaction [Amiodarone results in increased uptake of 1-acyl-2-(12-((7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)dodecanoyl)phosphatidylcholine]
Amiodarone affects the expression of FADS2 mRNA
CTD PMID:19483382 PMID:21123845 PMID:29248575 NCBI chr11:61,816,203...61,867,354
Ensembl chr11:61,792,980...61,867,354
JBrowse link
G FAM153A family with sequence similarity 153 member A increases expression EXP Amiodarone results in increased expression of FAM153A mRNA CTD PMID:19774075 NCBI chr 5:177,694,247...177,783,425
Ensembl chr 5:177,707,981...177,784,435
JBrowse link
G FAM81A family with sequence similarity 81 member A increases expression EXP Amiodarone results in increased expression of FAM81A mRNA CTD PMID:19774075 NCBI chr15:59,397,981...59,523,555
Ensembl chr15:59,372,693...59,523,555
JBrowse link
G FAM89A family with sequence similarity 89 member A increases expression EXP Amiodarone results in increased expression of FAM89A mRNA CTD PMID:19774075 NCBI chr 1:231,018,958...231,040,254
Ensembl chr 1:231,018,958...231,040,254
JBrowse link
G FANCA FA complementation group A increases expression EXP Amiodarone results in increased expression of FANCA mRNA CTD PMID:19774075 NCBI chr16:89,737,549...89,816,647
Ensembl chr16:89,726,683...89,816,977
JBrowse link
G FARP2 FERM, ARH/RhoGEF and pleckstrin domain protein 2 increases expression EXP Amiodarone results in increased expression of FARP2 mRNA CTD PMID:19774075 NCBI chr 2:241,356,285...241,494,841
Ensembl chr 2:241,356,285...241,494,841
JBrowse link
G FASN fatty acid synthase increases expression
decreases expression
affects expression
ISO
EXP
Amiodarone results in increased expression of FASN mRNA
Amiodarone results in decreased expression of FASN mRNA; Amiodarone results in decreased expression of FASN protein
Amiodarone affects the expression of FASN mRNA
CTD PMID:22291062 PMID:24489787 PMID:29248575 PMID:32084307 PMID:34259586 NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294
JBrowse link
G FBP1 fructose-bisphosphatase 1 affects expression ISO Amiodarone affects the expression of FBP1 mRNA CTD PMID:19483382 NCBI chr 9:94,603,133...94,640,263
Ensembl chr 9:94,603,133...94,640,249
JBrowse link
G FBXO16 F-box protein 16 increases expression EXP Amiodarone results in increased expression of FBXO16 mRNA CTD PMID:19774075 NCBI chr 8:28,428,412...28,490,229
Ensembl chr 8:28,348,287...28,490,278
JBrowse link
G FBXO32 F-box protein 32 increases expression EXP Amiodarone results in increased expression of FBXO32 mRNA CTD PMID:19774075 NCBI chr 8:123,497,889...123,541,206
Ensembl chr 8:123,497,889...123,541,206
JBrowse link
G FCGR2B Fc gamma receptor IIb increases expression ISO Amiodarone results in increased expression of FCGR2B mRNA CTD PMID:25580480 NCBI chr 1:161,647,243...161,678,654
Ensembl chr 1:161,663,143...161,678,654
JBrowse link
G FCRL1 Fc receptor like 1 increases expression EXP Amiodarone results in increased expression of FCRL1 mRNA CTD PMID:19774075 NCBI chr 1:157,794,403...157,820,120
Ensembl chr 1:157,792,249...157,820,120
JBrowse link
G FCRL2 Fc receptor like 2 increases expression EXP Amiodarone results in increased expression of FCRL2 mRNA CTD PMID:19774075 NCBI chr 1:157,745,733...157,777,132
Ensembl chr 1:157,745,733...157,777,132
JBrowse link
G FCRL3 Fc receptor like 3 increases expression EXP Amiodarone results in increased expression of FCRL3 mRNA CTD PMID:19774075 NCBI chr 1:157,676,481...157,700,956
Ensembl chr 1:157,674,321...157,700,769
JBrowse link
G FDFT1 farnesyl-diphosphate farnesyltransferase 1 affects expression
increases expression
ISO Amiodarone affects the expression of FDFT1 mRNA
Amiodarone results in increased expression of FDFT1 mRNA
CTD PMID:19483382 PMID:22291062 NCBI chr 8:11,795,582...11,839,298
Ensembl chr 8:11,795,573...11,839,395
JBrowse link
G FDPS farnesyl diphosphate synthase affects expression
increases expression
ISO Amiodarone affects the expression of FDPS mRNA
Amiodarone results in increased expression of FDPS mRNA
CTD PMID:19483382 PMID:22291062 NCBI chr 1:155,308,866...155,320,665
Ensembl chr 1:155,308,748...155,320,666
JBrowse link
G FDX2 ferredoxin 2 affects expression ISO Amiodarone affects the expression of FDX2 mRNA CTD PMID:19483382 NCBI chr19:10,310,045...10,316,015
Ensembl chr19:10,309,916...10,316,015
JBrowse link
G FFAR3 free fatty acid receptor 3 increases expression EXP Amiodarone results in increased expression of FFAR3 mRNA CTD PMID:19774075 NCBI chr19:35,358,151...35,360,489
Ensembl chr19:35,358,460...35,360,489
JBrowse link
G FGD4 FYVE, RhoGEF and PH domain containing 4 increases expression EXP Amiodarone results in increased expression of FGD4 mRNA CTD PMID:19774075 NCBI chr12:32,399,558...32,646,050
Ensembl chr12:32,399,558...32,646,050
JBrowse link
G FGD5 FYVE, RhoGEF and PH domain containing 5 increases expression EXP Amiodarone results in increased expression of FGD5 mRNA CTD PMID:19774075 NCBI chr 3:14,810,688...14,934,571
Ensembl chr 3:14,810,853...14,934,571
JBrowse link
G FGF21 fibroblast growth factor 21 increases expression ISO Amiodarone results in increased expression of FGF21 mRNA CTD PMID:24489787 NCBI chr19:48,755,524...48,758,330
Ensembl chr19:48,755,524...48,758,333
JBrowse link
G FGF7 fibroblast growth factor 7 increases expression ISO Amiodarone results in increased expression of FGF7 protein CTD PMID:32909452 NCBI chr15:49,423,242...49,488,775
Ensembl chr15:49,423,237...49,488,775
JBrowse link
G FGFR1OP2 FGFR1 oncogene partner 2 increases expression EXP Amiodarone results in increased expression of FGFR1OP2 mRNA CTD PMID:19774075 NCBI chr12:26,938,470...26,966,648
Ensembl chr12:26,938,470...26,966,650
JBrowse link
G FIBCD1 fibrinogen C domain containing 1 increases expression EXP Amiodarone results in increased expression of FIBCD1 mRNA CTD PMID:19774075 NCBI chr 9:130,902,440...130,940,709
Ensembl chr 9:130,902,438...130,939,286
JBrowse link
G FKBP10 FKBP prolyl isomerase 10 increases expression EXP Amiodarone results in increased expression of FKBP10 mRNA CTD PMID:19774075 NCBI chr17:41,813,004...41,823,213
Ensembl chr17:41,812,680...41,823,213
JBrowse link
G FKBP11 FKBP prolyl isomerase 11 decreases expression ISO Amiodarone results in decreased expression of FKBP11 mRNA CTD PMID:24535564 NCBI chr12:48,921,963...48,939,034
Ensembl chr12:48,921,518...48,926,474
JBrowse link
G FLCN folliculin increases expression EXP Amiodarone results in increased expression of FLCN mRNA CTD PMID:19774075 NCBI chr17:17,212,212...17,237,330
Ensembl chr17:17,212,212...17,237,188
JBrowse link
G FMO1 flavin containing dimethylaniline monoxygenase 1 affects expression ISO Amiodarone affects the expression of FMO1 mRNA CTD PMID:19483382 NCBI chr 1:171,248,494...171,285,978
Ensembl chr 1:171,248,471...171,285,978
JBrowse link
G FNDC4 fibronectin type III domain containing 4 increases expression EXP Amiodarone results in increased expression of FNDC4 mRNA CTD PMID:17175557 PMID:17567588 NCBI chr 2:27,491,883...27,495,200
Ensembl chr 2:27,491,883...27,495,200
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
EXP Amiodarone results in increased expression of FOS mRNA
[FOS protein co-treated with JUN protein] promotes the reaction [Amiodarone results in increased expression of AGT mRNA]
CTD PMID:17214612 PMID:19774075 PMID:36586010 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,283,190
JBrowse link
G FOSB FosB proto-oncogene, AP-1 transcription factor subunit increases expression EXP Amiodarone results in increased expression of FOSB mRNA CTD PMID:19774075 NCBI chr19:45,467,996...45,475,179
Ensembl chr19:45,467,995...45,475,179
JBrowse link
G FOXA1 forkhead box A1 decreases expression EXP Amiodarone results in decreased expression of FOXA1 mRNA CTD PMID:27089845 NCBI chr14:37,589,552...37,595,249
Ensembl chr14:37,589,552...37,596,059
JBrowse link
G FOXA3 forkhead box A3 decreases expression ISO Amiodarone results in decreased expression of FOXA3 mRNA CTD PMID:17991464 PMID:24535564 NCBI chr19:45,864,326...45,873,797
Ensembl chr19:45,863,989...45,873,797
JBrowse link
G FOXP3 forkhead box P3 increases expression EXP Amiodarone results in increased expression of FOXP3 mRNA CTD PMID:19774075 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,264,800
JBrowse link
G FRAS1 Fraser extracellular matrix complex subunit 1 increases expression EXP Amiodarone results in increased expression of FRAS1 mRNA CTD PMID:19774075 NCBI chr 4:78,057,323...78,544,269
Ensembl chr 4:78,057,323...78,544,269
JBrowse link
G FRMD3 FERM domain containing 3 increases expression EXP Amiodarone results in increased expression of FRMD3 mRNA CTD PMID:19774075 NCBI chr 9:83,242,992...83,585,794
Ensembl chr 9:83,242,990...83,538,546
JBrowse link
G FRMD5 FERM domain containing 5 increases expression EXP Amiodarone results in increased expression of FRMD5 mRNA CTD PMID:19774075 NCBI chr15:43,870,764...44,199,473
Ensembl chr15:43,870,761...44,195,271
JBrowse link
G FTL ferritin light chain increases expression EXP Amiodarone results in increased expression of FTL mRNA CTD PMID:36586010 NCBI chr19:48,965,309...48,966,879
Ensembl chr19:48,965,309...48,967,896
JBrowse link
G FUNDC2 FUN14 domain containing 2 increases expression EXP Amiodarone results in increased expression of FUNDC2 mRNA CTD PMID:19774075 NCBI chr  X:155,026,844...155,060,304
Ensembl chr  X:155,025,980...155,060,304
JBrowse link
G FUT4 fucosyltransferase 4 decreases expression ISO Amiodarone results in decreased expression of FUT4 mRNA CTD PMID:17991464 NCBI chr11:94,543,921...94,549,895
Ensembl chr11:94,543,921...94,549,895
JBrowse link
G FUZ fuzzy planar cell polarity protein increases expression EXP Amiodarone results in increased expression of FUZ mRNA CTD PMID:19774075 NCBI chr19:49,806,866...49,813,553
Ensembl chr19:49,806,866...49,817,376
JBrowse link
G FXYD1 FXYD domain containing ion transport regulator 1 increases expression EXP Amiodarone results in increased expression of FXYD1 mRNA CTD PMID:19774075 NCBI chr19:35,137,188...35,143,109
Ensembl chr19:35,138,824...35,143,109
JBrowse link
G G6PD glucose-6-phosphate dehydrogenase increases expression ISO
EXP
Amiodarone results in increased expression of G6PDX mRNA
Amiodarone results in increased expression of G6PD mRNA
CTD PMID:19224547 PMID:19774075 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572
JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha increases expression EXP Amiodarone results in increased expression of GADD45A mRNA CTD PMID:19774075 NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334
JBrowse link
G GADD45G growth arrest and DNA damage inducible gamma increases expression EXP Amiodarone results in increased expression of GADD45G mRNA CTD PMID:19774075 NCBI chr 9:89,605,012...89,606,555
Ensembl chr 9:89,605,012...89,606,555
JBrowse link
G GAL galanin and GMAP prepropeptide increases expression ISO Amiodarone results in increased expression of GAL mRNA CTD PMID:25580480 NCBI chr11:68,684,544...68,691,175
Ensembl chr11:68,683,779...68,691,175
JBrowse link
G GAL3ST3 galactose-3-O-sulfotransferase 3 increases expression EXP Amiodarone results in increased expression of GAL3ST3 mRNA CTD PMID:19774075 NCBI chr11:66,040,765...66,049,161
Ensembl chr11:66,040,765...66,049,161
JBrowse link
G GALNT17 polypeptide N-acetylgalactosaminyltransferase 17 increases expression EXP Amiodarone results in increased expression of GALNT17 mRNA CTD PMID:19774075 NCBI chr 7:71,132,144...71,713,599
Ensembl chr 7:71,132,144...71,713,600
JBrowse link
G GAMT guanidinoacetate N-methyltransferase affects expression ISO Amiodarone affects the expression of GAMT mRNA CTD PMID:19483382 NCBI chr19:1,397,026...1,401,542
Ensembl chr19:1,397,026...1,401,570
JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase affects expression ISO Amiodarone affects the expression of GAPDH mRNA CTD PMID:19483382 NCBI chr12:6,534,517...6,538,371
Ensembl chr12:6,534,512...6,538,374
JBrowse link
G GATA2 GATA binding protein 2 decreases expression ISO Amiodarone results in decreased expression of GATA2 mRNA CTD PMID:17991464 NCBI chr 3:128,479,422...128,493,201
Ensembl chr 3:128,479,427...128,493,201
JBrowse link
G GATB glutamyl-tRNA amidotransferase subunit B increases expression ISO Amiodarone results in increased expression of GATB mRNA CTD PMID:24535564 NCBI chr 4:151,670,504...151,761,007
Ensembl chr 4:151,670,504...151,761,007
JBrowse link
G GBE1 1,4-alpha-glucan branching enzyme 1 affects expression ISO Amiodarone affects the expression of GBE1 mRNA CTD PMID:19483382 NCBI chr 3:81,489,703...81,761,645
Ensembl chr 3:81,489,703...81,761,645
JBrowse link
G GBP2 guanylate binding protein 2 increases expression EXP Amiodarone results in increased expression of GBP2 mRNA CTD PMID:19774075 NCBI chr 1:89,106,132...89,126,114
Ensembl chr 1:89,106,132...89,150,456
JBrowse link
G GCHFR GTP cyclohydrolase I feedback regulator affects expression ISO Amiodarone affects the expression of GCHFR mRNA CTD PMID:19483382 NCBI chr15:40,764,068...40,767,708
Ensembl chr15:40,764,068...40,767,708
JBrowse link
G GCKR glucokinase regulator affects expression ISO Amiodarone affects the expression of GCKR mRNA CTD PMID:18355885 NCBI chr 2:27,496,839...27,523,684
Ensembl chr 2:27,496,839...27,523,684
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit increases expression EXP Amiodarone results in increased expression of GCLM mRNA CTD PMID:36586010 NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456
JBrowse link
G GDF15 growth differentiation factor 15 increases expression EXP Amiodarone results in increased expression of GDF15 mRNA CTD PMID:19774075 PMID:36586010 NCBI chr19:18,386,158...18,389,176
Ensembl chr19:18,374,731...18,389,176
JBrowse link
G GDF5 growth differentiation factor 5 increases expression EXP Amiodarone results in increased expression of GDF5 mRNA CTD PMID:19774075 NCBI chr20:35,433,347...35,454,749
Ensembl chr20:35,433,347...35,454,746
JBrowse link
G GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 increases expression EXP Amiodarone results in increased expression of GDPD3 mRNA CTD PMID:17175557 PMID:17567588 NCBI chr16:30,104,810...30,113,537
Ensembl chr16:30,104,810...30,113,537
JBrowse link
G GEM GTP binding protein overexpressed in skeletal muscle increases expression EXP Amiodarone results in increased expression of GEM mRNA CTD PMID:19774075 NCBI chr 8:94,249,253...94,262,319
Ensembl chr 8:94,249,253...94,262,350
JBrowse link
G GFAP glial fibrillary acidic protein increases expression ISO Amiodarone results in increased expression of GFAP mRNA CTD PMID:22954530 PMID:25659768 NCBI chr17:44,903,159...44,915,500
Ensembl chr17:44,903,159...44,916,937
JBrowse link
G GFOD1 Gfo/Idh/MocA-like oxidoreductase domain containing 1 increases expression EXP Amiodarone results in increased expression of GFOD1 mRNA CTD PMID:19774075 NCBI chr 6:13,357,830...13,487,600
Ensembl chr 6:13,357,830...13,487,662
JBrowse link
G GGH gamma-glutamyl hydrolase affects expression ISO Amiodarone affects the expression of GGH mRNA CTD PMID:19483382 NCBI chr 8:63,015,079...63,038,806
Ensembl chr 8:63,014,881...63,039,407
JBrowse link
G GH1 growth hormone 1 multiple interactions ISO Amiodarone inhibits the reaction [Triiodothyronine results in increased expression of GH1 mRNA] CTD PMID:2910914 NCBI chr17:63,917,203...63,918,839
Ensembl chr17:63,917,200...63,918,839
JBrowse link
G GINS1 GINS complex subunit 1 increases expression EXP Amiodarone results in increased expression of GINS1 mRNA CTD PMID:19774075 NCBI chr20:25,407,673...25,448,563
Ensembl chr20:25,391,008...25,452,700
JBrowse link
G GJA1 gap junction protein alpha 1 decreases expression ISO Amiodarone results in decreased expression of GJA1 mRNA CTD PMID:15520326 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727
JBrowse link
G GJA5 gap junction protein alpha 5 increases expression EXP Amiodarone results in increased expression of GJA5 mRNA CTD PMID:19774075 NCBI chr 1:147,756,199...147,773,351
Ensembl chr 1:147,756,199...147,773,362
JBrowse link
G GJB1 gap junction protein beta 1 affects expression ISO Amiodarone affects the expression of GJB1 mRNA CTD PMID:19483382 NCBI chr  X:71,215,239...71,225,516
Ensembl chr  X:71,212,811...71,225,516
JBrowse link
G GJD3 gap junction protein delta 3 increases expression EXP Amiodarone results in increased expression of GJD3 mRNA CTD PMID:19774075 NCBI chr17:40,360,652...40,364,737
Ensembl chr17:40,360,652...40,364,737
JBrowse link
G GK5 glycerol kinase 5 increases expression EXP Amiodarone results in increased expression of GK5 mRNA CTD PMID:19774075 NCBI chr 3:142,157,527...142,225,585
Ensembl chr 3:142,157,527...142,225,592
JBrowse link
G GKAP1 G kinase anchoring protein 1 increases expression EXP Amiodarone results in increased expression of GKAP1 mRNA CTD PMID:19774075 NCBI chr 9:83,739,425...83,817,769
Ensembl chr 9:83,739,425...83,829,516
JBrowse link
G GLS2 glutaminase 2 affects expression ISO Amiodarone affects the expression of GLS2 mRNA CTD PMID:18355885 NCBI chr12:56,470,952...56,488,161
Ensembl chr12:56,470,944...56,488,414
JBrowse link
G GLUD1 glutamate dehydrogenase 1 increases expression ISO Amiodarone results in increased expression of GLUD1 protein CTD PMID:16538043 NCBI chr10:87,050,202...87,094,843
Ensembl chr10:87,050,202...87,094,843
JBrowse link
G GNAS GNAS complex locus increases expression EXP Amiodarone results in increased expression of GNAS mRNA CTD PMID:19774075 NCBI chr20:58,839,748...58,911,192
Ensembl chr20:58,839,718...58,911,192
JBrowse link
G GNL1 G protein nucleolar 1 (putative) decreases expression ISO Amiodarone results in decreased expression of GNL1 mRNA CTD PMID:17991464 NCBI chr 6:30,541,381...30,556,489
Ensembl chr 6:30,541,381...30,556,489
JBrowse link
G GNPAT glyceronephosphate O-acyltransferase increases expression ISO Amiodarone results in increased expression of GNPAT mRNA CTD PMID:22291062 NCBI chr 1:231,241,212...231,277,973
Ensembl chr 1:231,241,207...231,277,973
JBrowse link
G GON4L gon-4 like increases expression EXP Amiodarone results in increased expression of GON4L mRNA CTD PMID:19774075 NCBI chr 1:155,745,112...155,859,431
Ensembl chr 1:155,749,659...155,859,400
JBrowse link
G GOT2 glutamic-oxaloacetic transaminase 2 affects expression ISO Amiodarone affects the expression of GOT2 mRNA CTD PMID:18355885 NCBI chr16:58,707,131...58,734,316
Ensembl chr16:58,707,131...58,734,342
JBrowse link
G GPAM glycerol-3-phosphate acyltransferase, mitochondrial increases expression ISO Amiodarone results in increased expression of GPAM mRNA CTD PMID:19224547 NCBI chr10:112,149,865...112,227,677
Ensembl chr10:112,149,865...112,215,377
JBrowse link
G GPAT3 glycerol-3-phosphate acyltransferase 3 increases expression ISO Amiodarone results in increased expression of GPAT3 mRNA CTD PMID:24535564 NCBI chr 4:83,535,587...83,605,875
Ensembl chr 4:83,535,914...83,605,875
JBrowse link
G GPLD1 glycosylphosphatidylinositol specific phospholipase D1 affects expression ISO Amiodarone affects the expression of GPLD1 mRNA CTD PMID:19483382 NCBI chr 6:24,423,969...24,495,287
Ensembl chr 6:24,424,565...24,495,205
JBrowse link
G GPRC5C G protein-coupled receptor class C group 5 member C increases expression EXP Amiodarone results in increased expression of GPRC5C mRNA CTD PMID:19774075 NCBI chr17:74,432,088...74,451,658
Ensembl chr17:74,424,851...74,451,653
JBrowse link
G GPT glutamic--pyruvic transaminase increases expression
multiple interactions
increases activity
EXP
ISO
Amiodarone results in increased expression of GPT protein
1-aminobenzotriazole promotes the reaction [Amiodarone promotes the reaction [Dexamethasone results in increased expression of GPT protein]]; [Dexamethasone results in increased susceptibility to Amiodarone] which results in increased expression of GPT protein; Amiodarone promotes the reaction [Dexamethasone results in increased expression of GPT protein]; gadolinium chloride inhibits the reaction [Amiodarone promotes the reaction [Dexamethasone results in increased expression of GPT protein]]
Amiodarone results in increased activity of GPT protein
CTD PMID:8522712 PMID:22291062 PMID:24685772 PMID:25900201 PMID:32084307 More... NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174
JBrowse link
G GPT2 glutamic--pyruvic transaminase 2 increases expression ISO Amiodarone results in increased expression of GPT2 mRNA CTD PMID:24489787 NCBI chr16:46,884,362...46,931,289
Ensembl chr16:46,884,362...46,931,289
JBrowse link
G GPX1 glutathione peroxidase 1 affects expression
decreases expression
multiple interactions
ISO
EXP
Amiodarone affects the expression of GPX1 mRNA
Amiodarone results in decreased expression of GPX1 mRNA
ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of GPX1 mRNA]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of GPX1 mRNA]]
CTD PMID:19483382 PMID:34434487 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605
JBrowse link
G GPX4 glutathione peroxidase 4 affects expression ISO Amiodarone affects the expression of GPX4 mRNA CTD PMID:19483382 NCBI chr19:1,103,994...1,106,779
Ensembl chr19:1,103,982...1,106,791
JBrowse link
G GRB14 growth factor receptor bound protein 14 affects expression ISO Amiodarone affects the expression of GRB14 mRNA CTD PMID:18355885 NCBI chr 2:164,492,417...164,621,482
Ensembl chr 2:164,492,417...164,621,482
JBrowse link
G GRINA glutamate ionotropic receptor NMDA type subunit associated protein 1 affects expression ISO Amiodarone affects the expression of GRINA mRNA CTD PMID:19483382 NCBI chr 8:143,990,056...143,993,415
Ensembl chr 8:143,990,056...143,993,415
JBrowse link
G GRM2 glutamate metabotropic receptor 2 increases expression EXP Amiodarone results in increased expression of GRM2 mRNA CTD PMID:19774075 NCBI chr 3:51,707,068...51,718,613
Ensembl chr 3:51,707,068...51,718,613
JBrowse link
G GRPEL1 GrpE like 1, mitochondrial affects expression ISO Amiodarone affects the expression of GRPEL1 mRNA CTD PMID:19483382 NCBI chr 4:7,058,895...7,068,064
Ensembl chr 4:7,058,671...7,068,085
JBrowse link
G GSK3B glycogen synthase kinase 3 beta decreases phosphorylation EXP
ISO
Amiodarone results in decreased phosphorylation of GSK3B protein CTD PMID:26515726 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994
JBrowse link
G GSN gelsolin increases expression ISO Amiodarone results in increased expression of GSN mRNA CTD PMID:17991464 NCBI chr 9:121,201,483...121,332,842
Ensembl chr 9:121,207,794...121,332,843
JBrowse link
G GSTA2 glutathione S-transferase alpha 2 increases expression EXP Amiodarone results in increased expression of GSTA2 mRNA CTD PMID:36586010 NCBI chr 6:52,750,087...52,763,475
Ensembl chr 6:52,750,087...52,763,475
JBrowse link
G GSTO2 glutathione S-transferase omega 2 increases expression EXP Amiodarone results in increased expression of GSTO2 mRNA CTD PMID:19774075 NCBI chr10:104,269,184...104,304,950
Ensembl chr10:104,268,873...104,304,950
JBrowse link
G GSTT1 glutathione S-transferase theta 1 affects expression ISO Amiodarone affects the expression of GSTT1 mRNA CTD PMID:19483382
G GSTT2B glutathione S-transferase theta 2B increases expression ISO Amiodarone results in increased expression of GSTT2 mRNA CTD PMID:24535564 NCBI chr22:23,957,414...23,961,206
Ensembl chr22:23,957,414...23,961,195
JBrowse link
G GSTT3P glutathione S-transferase theta 3, pseudogene increases expression ISO Amiodarone results in increased expression of GSTT3 mRNA CTD PMID:24535564
G GSTZ1 glutathione S-transferase zeta 1 increases expression EXP Amiodarone results in increased expression of GSTZ1 mRNA CTD PMID:19774075 NCBI chr14:77,321,036...77,331,597
Ensembl chr14:77,320,996...77,331,597
JBrowse link
G GTF2H5 general transcription factor IIH subunit 5 affects expression ISO Amiodarone affects the expression of GTF2H5 mRNA CTD PMID:19483382 NCBI chr 6:158,168,350...158,199,344
Ensembl chr 6:158,168,350...158,199,344
JBrowse link
G GUCY1A2 guanylate cyclase 1 soluble subunit alpha 2 increases expression EXP Amiodarone results in increased expression of GUCY1A2 mRNA CTD PMID:19774075 NCBI chr11:106,674,019...107,018,476
Ensembl chr11:106,674,019...107,018,476
JBrowse link
G GUCY1B1 guanylate cyclase 1 soluble subunit beta 1 increases expression EXP Amiodarone results in increased expression of GUCY1B1 mRNA CTD PMID:19774075 NCBI chr 4:155,759,021...155,807,811
Ensembl chr 4:155,758,992...155,807,811
JBrowse link
G GZMA granzyme A affects expression ISO Amiodarone affects the expression of GZMA mRNA CTD PMID:19483382 NCBI chr 5:55,102,646...55,110,252
Ensembl chr 5:55,102,646...55,110,252
JBrowse link
G H2AC17 H2A clustered histone 17 increases expression EXP Amiodarone results in increased expression of H2AC17 mRNA CTD PMID:19774075 NCBI chr 6:27,892,699...27,893,185
Ensembl chr 6:27,892,699...27,893,185
JBrowse link
G H2AJ H2A.J histone increases expression EXP Amiodarone results in increased expression of H2AJ mRNA CTD PMID:19774075 NCBI chr12:14,774,405...14,778,002
Ensembl chr12:14,774,405...14,778,002
JBrowse link
G H2BC6 H2B clustered histone 6 increases expression EXP Amiodarone results in increased expression of H2BC6 mRNA CTD PMID:19774075 NCBI chr 6:26,183,761...26,184,230
Ensembl chr 6:26,172,059...26,184,655
JBrowse link
G H3-3B H3.3 histone B affects expression ISO Amiodarone affects the expression of H3F3B mRNA CTD PMID:19483382 NCBI chr17:75,776,434...75,779,779
Ensembl chr17:75,776,434...75,785,893
JBrowse link
G H3C11 H3 clustered histone 11 increases expression EXP Amiodarone results in increased expression of H3C11 mRNA CTD PMID:19774075 NCBI chr 6:27,871,845...27,872,346
Ensembl chr 6:27,871,845...27,872,346
JBrowse link
G H3C12 H3 clustered histone 12 increases expression EXP Amiodarone results in increased expression of H3C12 mRNA CTD PMID:19774075 NCBI chr 6:27,890,315...27,890,826
Ensembl chr 6:27,890,315...27,893,106
JBrowse link
G H4C8 H4 clustered histone 8 increases expression EXP Amiodarone results in increased expression of H4C8 mRNA CTD PMID:19774075 NCBI chr 6:26,285,126...26,285,534
Ensembl chr 6:26,277,609...26,285,638
JBrowse link
G HAL histidine ammonia-lyase affects expression ISO Amiodarone affects the expression of HAL mRNA CTD PMID:18355885 PMID:19483382 NCBI chr12:95,972,662...95,996,344
Ensembl chr12:95,972,662...95,996,365
JBrowse link
G HAO2 hydroxyacid oxidase 2 affects expression ISO Amiodarone affects the expression of HAO2 mRNA CTD PMID:19483382 NCBI chr 1:119,368,785...119,394,130
Ensembl chr 1:119,368,779...119,394,130
JBrowse link
G HBA1 hemoglobin subunit alpha 1 affects expression ISO Amiodarone affects the expression of HBA-A2 mRNA CTD PMID:19483382 NCBI chr16:176,680...177,522
Ensembl chr16:176,680...177,522
JBrowse link
G HBB hemoglobin subunit beta affects expression ISO Amiodarone affects the expression of HBB mRNA CTD PMID:19483382 NCBI chr11:5,225,464...5,227,071
Ensembl chr11:5,225,464...5,229,395
JBrowse link
G HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 increases expression EXP Amiodarone results in increased expression of HCN1 mRNA CTD PMID:19774075 NCBI chr 5:45,254,948...45,696,380
Ensembl chr 5:45,254,948...45,696,498
JBrowse link
G HCN2 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 decreases expression ISO Amiodarone results in decreased expression of HCN2 mRNA CTD PMID:17711693 NCBI chr19:589,881...617,159
Ensembl chr19:589,881...617,159
JBrowse link
G HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 decreases expression ISO Amiodarone results in decreased expression of HCN4 mRNA CTD PMID:17711693 NCBI chr15:73,319,859...73,368,958
Ensembl chr15:73,319,859...73,368,958
JBrowse link
G HDC histidine decarboxylase affects expression ISO Amiodarone affects the expression of HDC mRNA CTD PMID:19483382 NCBI chr15:50,241,947...50,265,726
Ensembl chr15:50,241,947...50,265,965
JBrowse link
G HDX highly divergent homeobox increases expression EXP Amiodarone results in increased expression of HDX mRNA CTD PMID:19774075 NCBI chr  X:84,317,878...84,502,453
Ensembl chr  X:84,317,874...84,502,479
JBrowse link
G HELB DNA helicase B increases expression EXP Amiodarone results in increased expression of HELB mRNA CTD PMID:19774075 NCBI chr12:66,302,493...66,343,643
Ensembl chr12:66,302,493...66,343,643
JBrowse link
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression EXP Amiodarone results in increased expression of HERPUD1 mRNA CTD PMID:19774075 PMID:36586010 NCBI chr16:56,932,142...56,944,864
Ensembl chr16:56,932,142...56,944,864
JBrowse link
G HES6 hes family bHLH transcription factor 6 decreases expression ISO Amiodarone results in decreased expression of HES6 mRNA CTD PMID:17991464 NCBI chr 2:238,238,267...238,240,038
Ensembl chr 2:238,238,267...238,240,662
JBrowse link
G HEXA hexosaminidase subunit alpha multiple interactions
increases expression
EXP Amiodarone results in increased activity of and results in increased secretion of HEXA protein
Amiodarone results in increased expression of HEXA mRNA
CTD PMID:25881747 NCBI chr15:72,340,924...72,376,014
Ensembl chr15:72,340,924...72,376,420
JBrowse link
G HEXB hexosaminidase subunit beta multiple interactions EXP Amiodarone results in increased activity of and results in increased secretion of HEXB protein CTD PMID:25881747 NCBI chr 5:74,640,023...74,721,288
Ensembl chr 5:74,640,023...74,722,647
JBrowse link
G HEXIM1 HEXIM P-TEFb complex subunit 1 increases expression EXP Amiodarone results in increased expression of HEXIM1 mRNA CTD PMID:19774075 NCBI chr17:45,148,475...45,152,099
Ensembl chr17:45,148,475...45,152,099
JBrowse link
G HGD homogentisate 1,2-dioxygenase affects expression ISO Amiodarone affects the expression of HGD mRNA CTD PMID:19483382 NCBI chr 3:120,628,172...120,682,239
Ensembl chr 3:120,628,172...120,682,269
JBrowse link
G HGFAC HGF activator increases expression EXP Amiodarone results in increased expression of HGFAC mRNA CTD PMID:19774075 NCBI chr 4:3,441,005...3,449,486
Ensembl chr 4:3,441,968...3,449,486
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha decreases expression EXP Amiodarone results in decreased expression of HIF1A mRNA CTD PMID:35641671 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
JBrowse link
G HIRA histone cell cycle regulator increases expression EXP Amiodarone results in increased expression of HIRA mRNA CTD PMID:19774075 NCBI chr22:19,330,698...19,431,733
Ensembl chr22:19,330,698...19,447,450
JBrowse link
G HJV hemojuvelin BMP co-receptor increases expression ISO Amiodarone results in increased expression of HJV mRNA CTD PMID:24535564 NCBI chr 1:146,017,470...146,021,735
Ensembl chr 1:146,017,468...146,036,746
JBrowse link
G HLA-DPB1 major histocompatibility complex, class II, DP beta 1 increases expression EXP Amiodarone results in increased expression of HLA-DPB1 mRNA CTD PMID:19774075 NCBI chr 6:33,075,990...33,089,696
Ensembl chr 6:33,075,936...33,089,696
JBrowse link
G HMGB2 high mobility group box 2 affects expression ISO Amiodarone affects the expression of HMGB2 mRNA CTD PMID:18355885 NCBI chr 4:173,331,376...173,334,358
Ensembl chr 4:173,331,376...173,334,432
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase increases expression ISO Amiodarone results in increased expression of HMGCR mRNA CTD PMID:24489787 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001
JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO Amiodarone results in increased expression of HMGCS1 mRNA CTD PMID:22291062 NCBI chr 5:43,287,470...43,313,412
Ensembl chr 5:43,287,470...43,313,512
JBrowse link
G HMGN1 high mobility group nucleosome binding domain 1 affects expression ISO Amiodarone affects the expression of HMGN1 mRNA CTD PMID:19483382 NCBI chr21:39,342,315...39,349,088
Ensembl chr21:39,342,315...39,349,647
JBrowse link
G HMGXB4 HMG-box containing 4 increases expression EXP Amiodarone results in increased expression of HMGXB4 mRNA CTD PMID:19774075 NCBI chr22:35,241,536...35,295,807
Ensembl chr22:35,257,452...35,295,807
JBrowse link
G HMOX1 heme oxygenase 1 increases expression
affects expression
EXP
ISO
Amiodarone results in increased expression of HMOX1 mRNA
Amiodarone affects the expression of HMOX1 mRNA
CTD PMID:18020914 PMID:19224547 PMID:19774075 PMID:25659768 PMID:31324950 More... NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha increases expression ISO Amiodarone results in increased expression of HNF4A mRNA CTD PMID:24489787 NCBI chr20:44,355,699...44,434,596
Ensembl chr20:44,355,699...44,432,845
JBrowse link
G HNF4G hepatocyte nuclear factor 4 gamma increases expression EXP Amiodarone results in increased expression of HNF4G mRNA CTD PMID:19774075 NCBI chr 8:75,407,649...75,566,834
Ensembl chr 8:75,407,914...75,566,834
JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 increases expression EXP Amiodarone results in increased expression of HNRNPA1 mRNA CTD PMID:21163907 NCBI chr12:54,280,726...54,287,087
Ensembl chr12:54,280,193...54,287,088
JBrowse link
G HOXB6 homeobox B6 increases expression EXP Amiodarone results in increased expression of HOXB6 mRNA CTD PMID:19774075 NCBI chr17:48,595,751...48,604,986
Ensembl chr17:48,595,751...48,604,992
JBrowse link
G HOXC4 homeobox C4 increases expression EXP Amiodarone results in increased expression of HOXC4 mRNA CTD PMID:19774075 NCBI chr12:54,016,888...54,056,030
Ensembl chr12:54,016,931...54,056,030
JBrowse link
G HPN hepsin increases expression EXP Amiodarone results in increased expression of HPN mRNA CTD PMID:15342952 PMID:17567588 NCBI chr19:35,040,506...35,066,573
Ensembl chr19:35,040,506...35,066,573
JBrowse link
G HPRT1 hypoxanthine phosphoribosyltransferase 1 affects expression ISO Amiodarone affects the expression of HPRT1 mRNA CTD PMID:19483382 NCBI chr  X:134,460,165...134,500,668
Ensembl chr  X:134,460,165...134,520,513
JBrowse link
G HPS5 HPS5 biogenesis of lysosomal organelles complex 2 subunit 2 affects expression ISO Amiodarone affects the expression of HPS5 mRNA CTD PMID:19483382 NCBI chr11:18,278,670...18,322,174
Ensembl chr11:18,278,668...18,322,198
JBrowse link
G HRK harakiri, BCL2 interacting protein increases expression EXP Amiodarone results in increased expression of HRK mRNA CTD PMID:19774075 NCBI chr12:116,856,144...116,881,441
Ensembl chr12:116,856,144...116,881,441
JBrowse link
G HSCB HscB mitochondrial iron-sulfur cluster cochaperone increases expression ISO Amiodarone results in increased expression of HSCB mRNA CTD PMID:24535564 NCBI chr22:28,742,032...28,757,510
Ensembl chr22:28,742,039...28,757,515
JBrowse link
G HSD17B11 hydroxysteroid 17-beta dehydrogenase 11 increases expression ISO Amiodarone results in increased expression of HSD17B11 mRNA CTD PMID:24535564 NCBI chr 4:87,336,515...87,391,188
Ensembl chr 4:87,336,515...87,391,188
JBrowse link
G HSD17B4 hydroxysteroid 17-beta dehydrogenase 4 affects expression ISO Amiodarone affects the expression of HSD17B4 mRNA CTD PMID:19483382 NCBI chr 5:119,452,497...119,542,332
Ensembl chr 5:119,452,465...119,637,199
JBrowse link
G HSDL2 hydroxysteroid dehydrogenase like 2 affects expression ISO Amiodarone affects the expression of HSDL2 mRNA CTD PMID:19483382 NCBI chr 9:112,380,108...112,472,405
Ensembl chr 9:112,380,080...112,472,405
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions
EXP
ISO
Amiodarone results in increased expression of HSPA5 mRNA; Amiodarone results in increased expression of HSPA5 protein
1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of HSPA5 mRNA]
4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased expression of HSPA5 mRNA]; ursodoxicoltaurine inhibits the reaction [Amiodarone results in increased expression of HSPA5 mRNA]; ursodoxicoltaurine inhibits the reaction [Amiodarone results in increased expression of HSPA5 protein]
CTD PMID:25295624 PMID:34259586 PMID:36586010 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 increases expression ISO Amiodarone results in increased expression of HSPD1 protein CTD PMID:16538043 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737
JBrowse link
G HTATIP2 HIV-1 Tat interactive protein 2 increases expression ISO Amiodarone results in increased expression of HTATIP2 mRNA CTD PMID:24535564 NCBI chr11:20,363,714...20,383,782
Ensembl chr11:20,363,685...20,383,782
JBrowse link
G HTRA1 HtrA serine peptidase 1 affects expression ISO Amiodarone affects the expression of HTRA1 mRNA CTD PMID:19483382 NCBI chr10:122,461,553...122,514,907
Ensembl chr10:122,458,551...122,514,907
JBrowse link
G HTRA2 HtrA serine peptidase 2 increases expression ISO Amiodarone results in increased expression of HTRA2 mRNA CTD PMID:24489787 NCBI chr 2:74,529,405...74,533,556
Ensembl chr 2:74,529,596...74,533,350
JBrowse link
G HUS1 HUS1 checkpoint clamp component increases expression EXP Amiodarone results in increased expression of HUS1 mRNA CTD PMID:19774075 NCBI chr 7:47,963,288...47,979,615
Ensembl chr 7:47,961,882...47,979,615
JBrowse link
G ICAM1 intercellular adhesion molecule 1 increases expression
multiple interactions
EXP Amiodarone results in increased expression of ICAM1 mRNA
[Amiodarone co-treated with CYP3A4 protein] results in increased expression of ICAM1 protein
CTD PMID:19774075 PMID:22785256 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G ID2 inhibitor of DNA binding 2 increases expression EXP Amiodarone results in increased expression of ID2 mRNA CTD PMID:23397585 NCBI chr 2:8,682,056...8,684,461
Ensembl chr 2:8,678,845...8,684,461
JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 increases expression ISO Amiodarone results in increased expression of IDH2 mRNA CTD PMID:24489787 NCBI chr15:90,083,045...90,102,468
Ensembl chr15:90,083,045...90,102,477
JBrowse link
G IFNG interferon gamma multiple interactions
decreases expression
ISO
EXP
[Losartan co-treated with Vitamin D] inhibits the reaction [Amiodarone results in decreased expression of IFNG protein]; Losartan inhibits the reaction [Amiodarone results in decreased expression of IFNG protein]; Prednisolone inhibits the reaction [Amiodarone results in decreased expression of IFNG protein]; Vitamin D inhibits the reaction [Amiodarone results in decreased expression of IFNG protein]
Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein]
CTD PMID:25073960 PMID:34590760 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IGF1 insulin like growth factor 1 affects expression ISO Amiodarone affects the expression of IGF1 mRNA CTD PMID:19483382 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744
JBrowse link
G IGFALS insulin like growth factor binding protein acid labile subunit increases expression
affects expression
EXP
ISO
Amiodarone results in increased expression of IGFALS mRNA
Amiodarone affects the expression of IGFALS mRNA
CTD PMID:19483382 PMID:19774075 NCBI chr16:1,790,413...1,794,908
Ensembl chr16:1,790,413...1,794,971
JBrowse link
G IGFBP1 insulin like growth factor binding protein 1 increases expression EXP Amiodarone results in increased expression of IGFBP1 mRNA CTD PMID:27089845 NCBI chr 7:45,888,488...45,893,660
Ensembl chr 7:45,888,360...45,893,660
JBrowse link
G IGFBP2 insulin like growth factor binding protein 2 affects expression ISO Amiodarone affects the expression of IGFBP2 mRNA CTD PMID:19483382 NCBI chr 2:216,632,828...216,664,436
Ensembl chr 2:216,632,828...216,664,436
JBrowse link
G IGSF8 immunoglobulin superfamily member 8 increases expression EXP Amiodarone results in increased expression of IGSF8 mRNA CTD PMID:19774075 NCBI chr 1:160,091,339...160,099,468
Ensembl chr 1:160,091,340...160,098,943
JBrowse link
G IL10 interleukin 10 decreases expression
multiple interactions
EXP Amiodarone results in decreased expression of IL10 mRNA; Amiodarone results in decreased expression of IL10 protein
ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 protein]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 mRNA]]
CTD PMID:34434487 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL10RA interleukin 10 receptor subunit alpha increases expression EXP Amiodarone results in increased expression of IL10RA mRNA CTD PMID:19774075 NCBI chr11:117,986,394...118,003,037
Ensembl chr11:117,986,370...118,003,037
JBrowse link
G IL18 interleukin 18 multiple interactions ISO Amiodarone promotes the reaction [Dexamethasone results in decreased expression of IL18 mRNA] CTD PMID:25900201 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,251...112,164,096
JBrowse link
G IL1A interleukin 1 alpha increases expression
multiple interactions
EXP Amiodarone results in increased expression of IL1A mRNA
[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Amiodarone
CTD PMID:19362101 PMID:19774075 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G IL1B interleukin 1 beta multiple interactions
increases expression
ISO
EXP
[Amiodarone co-treated with Dexamethasone] results in decreased expression of IL1B mRNA
ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B protein]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B mRNA]]
Amiodarone results in increased expression of IL1B mRNA; Amiodarone results in increased expression of IL1B protein
CTD PMID:25580480 PMID:25900201 PMID:34434487 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL2 interleukin 2 multiple interactions EXP Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 protein] CTD PMID:25073960 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
JBrowse link
G IL33 interleukin 33 affects expression ISO Amiodarone affects the expression of IL33 mRNA CTD PMID:18355885 NCBI chr 9:6,215,149...6,257,983
Ensembl chr 9:6,215,786...6,257,983
JBrowse link
G IL4 interleukin 4 multiple interactions ISO
EXP
[Vitamin D co-treated with Losartan] inhibits the reaction [Amiodarone results in increased expression of IL4 protein]; Losartan inhibits the reaction [Amiodarone results in increased expression of IL4 protein]; Prednisolone inhibits the reaction [Amiodarone results in increased expression of IL4 protein]; Vitamin D inhibits the reaction [Amiodarone results in increased expression of IL4 protein]
Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4 protein]
CTD PMID:25073960 PMID:34590760 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
JBrowse link
G IL6 interleukin 6 increases expression
multiple interactions
increases secretion
EXP
ISO
Amiodarone results in increased expression of IL6 mRNA; Amiodarone results in increased expression of IL6 protein
[Losartan co-treated with Vitamin D] inhibits the reaction [Amiodarone results in increased expression of IL6 protein]; Losartan inhibits the reaction [Amiodarone results in increased expression of IL6 protein]; Prednisolone inhibits the reaction [Amiodarone results in increased expression of IL6 protein]; Vitamin D inhibits the reaction [Amiodarone results in increased expression of IL6 protein]
[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Amiodarone; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 protein]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 mRNA]]; Prednisolone inhibits the reaction [Amiodarone results in increased secretion of IL6 protein]
CTD PMID:11288978 PMID:19362101 PMID:34434487 PMID:34590760 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G IMPA1 inositol monophosphatase 1 affects expression ISO Amiodarone affects the expression of IMPA1 mRNA CTD PMID:19483382 NCBI chr 8:81,656,914...81,686,325
Ensembl chr 8:81,656,914...81,686,331
JBrowse link
G INHBA inhibin subunit beta A decreases expression ISO Amiodarone results in decreased expression of INHBA mRNA CTD PMID:24535564 NCBI chr 7:41,685,114...41,705,406
Ensembl chr 7:41,667,168...41,705,834
JBrowse link
G INHBE inhibin subunit beta E affects expression
increases expression
ISO
EXP
Amiodarone affects the expression of INHBE mRNA
Amiodarone results in increased expression of INHBE mRNA
CTD PMID:15342952 PMID:17175557 PMID:17567588 PMID:19483382 PMID:19774075 NCBI chr12:57,455,307...57,458,025
Ensembl chr12:57,452,323...57,459,280
JBrowse link
G INKA2 inka box actin regulator 2 increases expression EXP Amiodarone results in increased expression of INKA2 mRNA CTD PMID:19774075 NCBI chr 1:111,722,064...111,755,797
Ensembl chr 1:111,680,630...111,755,824
JBrowse link
G INS insulin multiple interactions ISO INS inhibits the reaction [Amiodarone results in increased phosphorylation of LIPE protein] CTD PMID:28962527 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221
JBrowse link
G IPPK inositol-pentakisphosphate 2-kinase increases expression EXP Amiodarone results in increased expression of IPPK mRNA CTD PMID:19774075 NCBI chr 9:92,613,183...92,670,131
Ensembl chr 9:92,613,183...92,670,131
JBrowse link
G IRAK2 interleukin 1 receptor associated kinase 2 increases expression EXP Amiodarone results in increased expression of IRAK2 mRNA CTD PMID:19774075 NCBI chr 3:10,164,919...10,243,745
Ensembl chr 3:10,164,919...10,243,745
JBrowse link
G IRF1 interferon regulatory factor 1 increases expression EXP Amiodarone results in increased expression of IRF1 mRNA CTD PMID:19774075 NCBI chr 5:132,481,609...132,490,773
Ensembl chr 5:132,440,440...132,508,719
JBrowse link
G ISX intestine specific homeobox increases expression EXP Amiodarone results in increased expression of ISX mRNA CTD PMID:19774075 NCBI chr22:35,066,158...35,087,387
Ensembl chr22:35,066,136...35,087,387
JBrowse link
G ISYNA1 inositol-3-phosphate synthase 1 affects expression ISO Amiodarone affects the expression of ISYNA1 mRNA CTD PMID:19483382 NCBI chr19:18,434,388...18,438,133
Ensembl chr19:18,434,388...18,438,167
JBrowse link
G ITGB5 integrin subunit beta 5 decreases expression EXP Amiodarone results in decreased expression of ITGB5 mRNA CTD PMID:23397585 NCBI chr 3:124,761,948...124,901,418
Ensembl chr 3:124,761,948...124,901,418
JBrowse link
G ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 increases expression EXP Amiodarone results in increased expression of ITIH2 mRNA CTD PMID:19774075 NCBI chr10:7,703,316...7,749,520
Ensembl chr10:7,703,316...7,749,520
JBrowse link
G ITIH4 inter-alpha-trypsin inhibitor heavy chain 4 affects expression ISO Amiodarone affects the expression of ITIH4 mRNA CTD PMID:19483382 NCBI chr 3:52,812,962...52,830,672
Ensembl chr 3:52,812,962...52,830,688
JBrowse link
G IVNS1ABP influenza virus NS1A binding protein increases expression ISO Amiodarone results in increased expression of IVNS1ABP mRNA CTD PMID:17991464 NCBI chr 1:185,296,388...185,317,243
Ensembl chr 1:185,292,931...185,317,273
JBrowse link
G JAK1 Janus kinase 1 affects expression ISO Amiodarone affects the expression of JAK1 mRNA CTD PMID:19483382 NCBI chr 1:64,833,229...65,067,746
Ensembl chr 1:64,833,223...65,067,754
JBrowse link
G JAKMIP3 Janus kinase and microtubule interacting protein 3 increases expression EXP Amiodarone results in increased expression of JAKMIP3 mRNA CTD PMID:19774075 NCBI chr10:132,036,364...132,184,858
Ensembl chr10:132,036,336...132,184,858
JBrowse link
G JRKL JRK like increases expression EXP Amiodarone results in increased expression of JRKL mRNA CTD PMID:19774075 NCBI chr11:96,390,013...96,393,561
Ensembl chr11:96,389,989...96,507,574
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit increases expression
increases phosphorylation
multiple interactions
ISO
EXP
Amiodarone results in increased expression of JUN mRNA; Amiodarone results in increased expression of JUN protein
Amiodarone results in increased phosphorylation of JUN protein
[Losartan co-treated with Vitamin D] inhibits the reaction [Amiodarone results in increased phosphorylation of JUN protein]; Losartan inhibits the reaction [Amiodarone results in increased phosphorylation of JUN protein]; Prednisolone inhibits the reaction [Amiodarone results in increased phosphorylation of JUN protein]; Vitamin D inhibits the reaction [Amiodarone results in increased phosphorylation of JUN protein]
[FOS protein co-treated with JUN protein] promotes the reaction [Amiodarone results in increased expression of AGT mRNA]; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of JUN protein]
CTD PMID:11597910 PMID:17214612 PMID:25073960 PMID:34590760 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
JBrowse link
G KCNA4 potassium voltage-gated channel subfamily A member 4 increases expression ISO Amiodarone results in increased expression of KCNA4 mRNA CTD PMID:15520326 NCBI chr11:30,009,730...30,017,030
Ensembl chr11:30,009,730...30,017,030
JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 decreases expression ISO Amiodarone results in decreased expression of KCNA5 mRNA CTD PMID:8973384 PMID:9302343 PMID:15520326 NCBI chr12:5,043,879...5,046,788
Ensembl chr12:5,043,879...5,046,788
JBrowse link
G KCNAB1 potassium voltage-gated channel subfamily A regulatory beta subunit 1 increases expression ISO Amiodarone results in increased expression of KCNAB1 mRNA CTD PMID:15520326 NCBI chr 3:156,118,211...156,539,138
Ensembl chr 3:156,037,701...156,538,756
JBrowse link
G KCNB1 potassium voltage-gated channel subfamily B member 1 decreases expression ISO Amiodarone results in decreased expression of KCNB1 mRNA CTD PMID:15520326 NCBI chr20:49,363,877...49,483,362
Ensembl chr20:49,293,394...49,484,297
JBrowse link
G KCND2 potassium voltage-gated channel subfamily D member 2 decreases expression ISO Amiodarone results in decreased expression of KCND2 mRNA CTD PMID:15520326 NCBI chr 7:120,272,908...120,750,337
Ensembl chr 7:120,273,175...120,750,337
JBrowse link
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 increases expression ISO Amiodarone results in increased expression of KCNE3 mRNA CTD PMID:15520326 NCBI chr11:74,454,841...74,467,549
Ensembl chr11:74,454,841...74,467,729
JBrowse link
G KCNE5 potassium voltage-gated channel subfamily E regulatory subunit 5 increases expression EXP Amiodarone results in increased expression of KCNE5 mRNA CTD PMID:19774075 NCBI chr  X:109,623,700...109,625,172
Ensembl chr  X:109,623,700...109,625,172
JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 affects activity
increases expression
decreases activity
multiple interactions
EXP
ISO
Amiodarone affects the activity of KCNH2 protein
Amiodarone results in increased expression of KCNH2 mRNA
Amiodarone results in decreased activity of KCNH2 protein
Amiodarone binds to and results in decreased activity of KCNH2 protein; Amiodarone inhibits the reaction [KCNH2 protein results in increased transport of Thallium]; Amiodarone promotes the reaction [naringenin results in decreased activity of KCNH2 protein]; naringenin promotes the reaction [Amiodarone results in decreased activity of KCNH2 protein]; Potassium inhibits the reaction [Amiodarone results in decreased activity of KCNH2 protein]
CTD PMID:10208308 PMID:11238279 PMID:15272206 PMID:15618689 PMID:15671647 More... NCBI chr 7:150,944,961...150,978,321
Ensembl chr 7:150,944,961...150,978,321
JBrowse link
G KCNJ2 potassium inwardly rectifying channel subfamily J member 2 increases expression EXP Amiodarone results in increased expression of KCNJ2 mRNA CTD PMID:19774075 NCBI chr17:70,169,532...70,180,044
Ensembl chr17:70,168,673...70,180,044
JBrowse link
G KCNK1 potassium two pore domain channel subfamily K member 1 increases expression ISO Amiodarone results in increased expression of KCNK1 mRNA CTD PMID:15520326 NCBI chr 1:233,614,106...233,672,514
Ensembl chr 1:233,614,106...233,672,514
JBrowse link
G KCNK12 potassium two pore domain channel subfamily K member 12 increases expression EXP Amiodarone results in increased expression of KCNK12 mRNA CTD PMID:19774075 NCBI chr 2:47,509,290...47,570,985
Ensembl chr 2:47,509,290...47,570,985
JBrowse link
G KCNMA1 potassium calcium-activated channel subfamily M alpha 1 increases expression EXP Amiodarone results in increased expression of KCNMA1 mRNA CTD PMID:19774075 NCBI chr10:76,869,602...77,637,808
Ensembl chr10:76,869,601...77,638,369
JBrowse link
G KCTD14 potassium channel tetramerization domain containing 14 increases expression EXP Amiodarone results in increased expression of KCTD14 mRNA CTD PMID:19774075 NCBI chr11:78,015,715...78,046,191
Ensembl chr11:78,015,715...78,046,191
JBrowse link
G KDELR2 KDEL endoplasmic reticulum protein retention receptor 2 affects expression ISO Amiodarone affects the expression of KDELR2 mRNA CTD PMID:19483382 NCBI chr 7:6,461,089...6,484,152
Ensembl chr 7:6,445,953...6,484,190
JBrowse link
G KDR kinase insert domain receptor affects expression ISO Amiodarone affects the expression of KDR mRNA CTD PMID:19483382 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595
JBrowse link
G KEAP1 kelch like ECH associated protein 1 decreases expression ISO Amiodarone results in decreased expression of KEAP1 mRNA CTD PMID:17991464 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558
JBrowse link
G KHDRBS3 KH RNA binding domain containing, signal transduction associated 3 increases expression ISO Amiodarone results in increased expression of KHDRBS3 mRNA CTD PMID:24535564 NCBI chr 8:135,457,456...135,656,516
Ensembl chr 8:135,457,456...135,656,722
JBrowse link
G KIF16B kinesin family member 16B increases expression EXP Amiodarone results in increased expression of KIF16B mRNA CTD PMID:19774075 NCBI chr20:16,272,104...16,573,448
Ensembl chr20:16,272,104...16,573,448
JBrowse link
G KIF17 kinesin family member 17 increases expression EXP Amiodarone results in increased expression of KIF17 mRNA CTD PMID:19774075 NCBI chr 1:20,661,630...20,718,007
Ensembl chr 1:20,664,014...20,718,017
JBrowse link
G KIFC1 kinesin family member C1 increases expression EXP Amiodarone results in increased expression of KIFC1 mRNA CTD PMID:19774075 NCBI chr 6:33,391,461...33,409,896
Ensembl chr 6:33,391,823...33,409,896
JBrowse link
G KIR2DL5B killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 5B increases expression EXP Amiodarone results in increased expression of KIR2DL5B mRNA CTD PMID:19774075
G KITLG KIT ligand increases expression EXP Amiodarone results in increased expression of KITLG mRNA CTD PMID:19774075 NCBI chr12:88,492,793...88,580,471
Ensembl chr12:88,492,793...88,580,851
JBrowse link
G KLF10 KLF transcription factor 10 increases expression EXP Amiodarone results in increased expression of KLF10 mRNA CTD PMID:19774075 NCBI chr 8:102,648,784...102,655,725
Ensembl chr 8:102,648,784...102,655,725
JBrowse link
G KLF15 KLF transcription factor 15 increases expression EXP Amiodarone results in increased expression of KLF15 mRNA CTD PMID:19774075 NCBI chr 3:126,288,125...126,357,408
Ensembl chr 3:126,342,635...126,357,408
JBrowse link
G KLF16 KLF transcription factor 16 increases expression EXP Amiodarone results in increased expression of KLF16 mRNA CTD PMID:19774075 NCBI chr19:1,852,399...1,876,536
Ensembl chr19:1,852,399...1,863,579
JBrowse link
G KLF4 KLF transcription factor 4 increases expression EXP Amiodarone results in increased expression of KLF4 mRNA CTD PMID:19774075 NCBI chr 9:107,484,852...107,489,769
Ensembl chr 9:107,484,852...107,490,482
JBrowse link
G KLHL28 kelch like family member 28 increases expression EXP Amiodarone results in increased expression of KLHL28 mRNA CTD PMID:19774075 NCBI chr14:44,924,324...44,961,947
Ensembl chr14:44,924,324...45,042,322
JBrowse link
G KLK14 kallikrein related peptidase 14 increases expression EXP Amiodarone results in increased expression of KLK14 mRNA CTD PMID:19774075 NCBI chr19:51,077,494...51,084,210
Ensembl chr19:51,077,495...51,084,245
JBrowse link
G KRT17 keratin 17 increases expression EXP Amiodarone results in increased expression of KRT17 mRNA CTD PMID:19774075 NCBI chr17:41,619,442...41,624,575
Ensembl chr17:41,619,442...41,624,842
JBrowse link
G KRT23 keratin 23 increases expression ISO Amiodarone results in increased expression of KRT23 mRNA CTD PMID:24535564 NCBI chr17:40,922,700...40,937,646
Ensembl chr17:40,922,700...40,937,646
JBrowse link
G KRT8 keratin 8 affects expression ISO Amiodarone affects the expression of KRT8 mRNA CTD PMID:19483382 NCBI chr12:52,897,191...52,949,860
Ensembl chr12:52,897,187...52,949,954
JBrowse link
G L3MBTL1 L3MBTL histone methyl-lysine binding protein 1 increases expression EXP Amiodarone results in increased expression of L3MBTL1 mRNA CTD PMID:19774075 NCBI chr20:43,507,697...43,550,954
Ensembl chr20:43,489,442...43,550,954
JBrowse link
G LACRT lacritin increases expression EXP Amiodarone results in increased expression of LACRT mRNA CTD PMID:19774075 NCBI chr12:54,630,811...54,634,895
Ensembl chr12:54,630,811...54,634,895
JBrowse link
G LAMA2 laminin subunit alpha 2 increases expression ISO Amiodarone results in increased expression of LAMA2 mRNA CTD PMID:24489787 NCBI chr 6:128,883,138...129,516,566
Ensembl chr 6:128,883,138...129,516,566
JBrowse link
G LARS2 leucyl-tRNA synthetase 2, mitochondrial increases expression ISO Amiodarone results in increased expression of LARS2 mRNA CTD PMID:24489787 NCBI chr 3:45,388,576...45,549,407
Ensembl chr 3:45,388,561...45,554,726
JBrowse link
G LCAT lecithin-cholesterol acyltransferase affects expression
increases expression
ISO Amiodarone affects the expression of LCAT mRNA
Amiodarone results in increased expression of LCAT mRNA
CTD PMID:19483382 PMID:22291062 NCBI chr16:67,939,750...67,944,120
Ensembl chr16:67,939,750...67,944,131
JBrowse link
G LCMT1 leucine carboxyl methyltransferase 1 affects expression ISO Amiodarone affects the expression of LCMT1 mRNA CTD PMID:19483382 NCBI chr16:25,111,742...25,178,228
Ensembl chr16:25,111,731...25,178,231
JBrowse link
G LCTL lactase like increases expression EXP Amiodarone results in increased expression of LCTL mRNA CTD PMID:19774075 NCBI chr15:66,547,532...66,565,998
Ensembl chr15:66,547,179...66,565,998
JBrowse link
G LDLR low density lipoprotein receptor multiple interactions
decreases expression
EXP
ISO
Amiodarone promotes the reaction [Triiodothyronine results in increased expression of LDLR mRNA]
Amiodarone results in decreased expression of LDLR mRNA; Amiodarone results in decreased expression of LDLR protein
Triiodothyronine inhibits the reaction [Amiodarone results in decreased expression of LDLR protein]
CTD PMID:8137927 PMID:9071962 PMID:9712728 PMID:9751232 PMID:12538616 NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,418...11,133,820
JBrowse link
G LELP1 late cornified envelope like proline rich 1 increases expression EXP Amiodarone results in increased expression of LELP1 mRNA CTD PMID:19774075 NCBI chr 1:153,203,430...153,205,120
Ensembl chr 1:153,203,430...153,205,120
JBrowse link
G LHCGR luteinizing hormone/choriogonadotropin receptor increases expression EXP Amiodarone results in increased expression of LHCGR mRNA CTD PMID:19774075 NCBI chr 2:48,686,774...48,755,724
Ensembl chr 2:48,686,774...48,755,730
JBrowse link
G LIF LIF interleukin 6 family cytokine increases expression EXP Amiodarone results in increased expression of LIF mRNA CTD PMID:19774075 NCBI chr22:30,240,453...30,246,759
Ensembl chr22:30,240,453...30,246,759
JBrowse link
G LIMS3 LIM zinc finger domain containing 3 increases expression EXP Amiodarone results in increased expression of LIMS3 mRNA CTD PMID:19774075 NCBI chr 2:109,898,688...109,925,625
Ensembl chr 2:109,898,428...109,925,625
JBrowse link
G LIN7A lin-7 homolog A, crumbs cell polarity complex component increases expression EXP Amiodarone results in increased expression of LIN7A mRNA CTD PMID:19774075 NCBI chr12:80,792,520...80,937,934
Ensembl chr12:80,792,520...80,937,934
JBrowse link
G LINC00472 long intergenic non-protein coding RNA 472 increases expression EXP Amiodarone results in increased expression of LINC00472 mRNA CTD PMID:19774075 NCBI chr 6:71,407,864...71,420,745
Ensembl chr 6:71,187,161...71,420,745
JBrowse link
G LINC01547 long intergenic non-protein coding RNA 1547 increases expression EXP Amiodarone results in increased expression of LINC01547 mRNA CTD PMID:19774075 NCBI chr21:44,933,284...44,939,913
Ensembl chr21:44,932,814...44,939,951
JBrowse link
G LIPC lipase C, hepatic type affects expression ISO Amiodarone affects the expression of LIPC mRNA CTD PMID:19483382 NCBI chr15:58,431,991...58,569,844
Ensembl chr15:58,410,569...58,569,844
JBrowse link
G LIPE lipase E, hormone sensitive type multiple interactions
increases phosphorylation
ISO INS inhibits the reaction [Amiodarone results in increased phosphorylation of LIPE protein] CTD PMID:28962527 PMID:34259586 NCBI chr19:42,401,514...42,427,388
Ensembl chr19:42,401,497...42,427,388
JBrowse link
G LOX lysyl oxidase affects expression ISO Amiodarone affects the expression of LOX mRNA CTD PMID:18355885 PMID:19483382 NCBI chr 5:122,063,195...122,078,259
Ensembl chr 5:122,063,195...122,078,413
JBrowse link
G LPCAT3 lysophosphatidylcholine acyltransferase 3 increases expression ISO Amiodarone results in increased expression of LPCAT3 mRNA CTD PMID:24489787 NCBI chr12:6,976,185...7,018,476
Ensembl chr12:6,976,185...7,018,477
JBrowse link
G LPGAT1 lysophosphatidylglycerol acyltransferase 1 increases expression ISO Amiodarone results in increased expression of LPGAT1 mRNA CTD PMID:22291062 NCBI chr 1:211,743,457...211,830,763
Ensembl chr 1:211,743,457...211,830,763
JBrowse link
G LPIN3 lipin 3 increases expression ISO Amiodarone results in increased expression of LPIN3 mRNA CTD PMID:24489787 NCBI chr20:41,340,821...41,360,582
Ensembl chr20:41,340,821...41,360,582
JBrowse link
G LRP3 LDL receptor related protein 3 affects expression ISO Amiodarone affects the expression of LRP3 mRNA CTD PMID:19483382 NCBI chr19:33,194,330...33,208,864
Ensembl chr19:33,177,603...33,208,864
JBrowse link
G LRP5 LDL receptor related protein 5 increases expression EXP Amiodarone results in increased expression of LRP5 mRNA CTD PMID:19774075 NCBI chr11:68,298,412...68,449,275
Ensembl chr11:68,312,591...68,449,275
JBrowse link
G LSS lanosterol synthase increases expression
affects expression
ISO
EXP
Amiodarone results in increased expression of LSS mRNA
Amiodarone affects the expression of LSS mRNA
CTD PMID:15342952 PMID:17567588 PMID:19224547 PMID:22291062 PMID:24489787 More... NCBI chr21:46,188,446...46,228,774
Ensembl chr21:46,188,141...46,228,824
JBrowse link
G LY6D lymphocyte antigen 6 family member D increases expression ISO Amiodarone results in increased expression of LY6D mRNA CTD PMID:24489787 NCBI chr 8:142,784,882...142,786,539
Ensembl chr 8:142,784,882...142,786,539
JBrowse link
G LYZ lysozyme increases expression EXP Amiodarone results in increased expression of LYZ mRNA CTD PMID:19774075 NCBI chr12:69,348,381...69,354,234
Ensembl chr12:69,348,381...69,354,234
JBrowse link
G MACROD2 mono-ADP ribosylhydrolase 2 increases expression EXP Amiodarone results in increased expression of MACROD2 mRNA CTD PMID:19774075 NCBI chr20:13,995,516...16,053,197
Ensembl chr20:13,995,369...16,053,197
JBrowse link
G MACROH2A1 macroH2A.1 histone affects expression ISO Amiodarone affects the expression of MACROH2A1 mRNA CTD PMID:18355885 NCBI chr 5:135,334,381...135,399,887
Ensembl chr 5:135,334,381...135,399,914
JBrowse link
G MAFF MAF bZIP transcription factor F increases expression EXP Amiodarone results in increased expression of MAFF mRNA CTD PMID:36586010 NCBI chr22:38,201,994...38,216,511
Ensembl chr22:38,200,767...38,216,507
JBrowse link
G MAFG MAF bZIP transcription factor G increases expression EXP Amiodarone results in increased expression of MAFG mRNA CTD PMID:19774075 PMID:36586010 NCBI chr17:81,918,270...81,931,244
Ensembl chr17:81,918,270...81,927,735
JBrowse link
G MAGED4B MAGE family member D4B increases expression EXP Amiodarone results in increased expression of MAGED4B mRNA CTD PMID:19774075 NCBI chr  X:52,061,827...52,069,272
Ensembl chr  X:52,061,827...52,069,219
JBrowse link
G MAN2B1 mannosidase alpha class 2B member 1 affects expression ISO Amiodarone affects the expression of MAN2B1 mRNA CTD PMID:19483382 NCBI chr19:12,646,512...12,666,742
Ensembl chr19:12,643,831...12,666,742
JBrowse link
G MANBA mannosidase beta affects expression ISO Amiodarone affects the expression of MANBA mRNA CTD PMID:18355885 NCBI chr 4:102,630,770...102,760,968
Ensembl chr 4:102,630,770...102,760,994
JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta increases lipidation
multiple interactions
EXP Amiodarone results in increased lipidation of MAP1LC3B protein
Amiodarone results in increased expression of and results in increased lipidation of MAP1LC3B protein; Amiodarone results in increased lipidation of and results in increased localization of MAP1LC3B protein
CTD PMID:25881747 PMID:32651653 PMID:37661063 NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779
JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 multiple interactions ISO MAP2K1 protein inhibits the reaction [Amiodarone results in decreased expression of SNAI1 protein] CTD PMID:26515726 NCBI chr15:66,386,912...66,491,544
Ensembl chr15:66,386,837...66,491,656
JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 affects expression ISO Amiodarone affects the expression of MAP2K2 mRNA CTD PMID:19483382 NCBI chr19:4,090,321...4,124,122
Ensembl chr19:4,090,321...4,124,122
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 increases phosphorylation
decreases phosphorylation
multiple interactions
ISO
EXP
Amiodarone results in increased phosphorylation of MAPK1 protein
Amiodarone results in decreased phosphorylation of MAPK1 protein
[Losartan co-treated with Vitamin D] inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK1 protein]; Losartan inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK1 protein]; Prednisolone inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK1 protein]; Vitamin D inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK1 protein]
CTD PMID:26515726 PMID:31071512 PMID:34590760 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK14 mitogen-activated protein kinase 14 increases phosphorylation
multiple interactions
ISO Amiodarone results in increased phosphorylation of MAPK14 protein
[Losartan co-treated with Vitamin D] inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK14 protein]; Losartan inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK14 protein]; Prednisolone inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK14 protein]; Vitamin D inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK14 protein]
CTD PMID:34590760 NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,752...36,122,511
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 increases phosphorylation
decreases phosphorylation
multiple interactions
ISO
EXP
Amiodarone results in increased phosphorylation of MAPK3 protein
Amiodarone results in decreased phosphorylation of MAPK3 protein
[Losartan co-treated with Vitamin D] inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK3 protein]; Losartan inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK3 protein]; Prednisolone inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK3 protein]; Vitamin D inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK3 protein]
CTD PMID:26515726 PMID:31071512 PMID:34590760 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MAPK8 mitogen-activated protein kinase 8 increases phosphorylation
multiple interactions
ISO
EXP
Amiodarone results in increased phosphorylation of MAPK8 protein
Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK8 protein]
CTD PMID:25073960 PMID:34259586 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360
JBrowse link
G MASP1 MBL associated serine protease 1 increases expression EXP Amiodarone results in increased expression of MASP1 mRNA CTD PMID:19774075 NCBI chr 3:187,217,282...187,291,737
Ensembl chr 3:187,217,282...187,291,980
JBrowse link
G MASP2 MBL associated serine protease 2 affects expression ISO Amiodarone affects the expression of MASP2 mRNA CTD PMID:19483382 NCBI chr 1:11,026,523...11,047,239
Ensembl chr 1:11,022,009...11,047,239
JBrowse link
G MBP myelin basic protein affects expression ISO Amiodarone affects the expression of MBP mRNA CTD PMID:25659768 NCBI chr18:76,978,833...77,133,708
Ensembl chr18:76,978,827...77,133,683
JBrowse link
G MCAM melanoma cell adhesion molecule increases expression EXP Amiodarone results in increased expression of MCAM mRNA CTD PMID:19774075 NCBI chr11:119,308,529...119,317,130
Ensembl chr11:119,308,529...119,321,521
JBrowse link
G MCF2 MCF.2 cell line derived transforming sequence increases expression EXP Amiodarone results in increased expression of MCF2 mRNA CTD PMID:19774075 NCBI chr  X:139,581,770...139,708,167
Ensembl chr  X:139,581,770...139,708,216
JBrowse link
G ME1 malic enzyme 1 increases expression
affects expression
ISO Amiodarone results in increased expression of ME1 protein
Amiodarone affects the expression of ME1 mRNA
CTD PMID:16538043 PMID:19483382 NCBI chr 6:83,210,402...83,431,051
Ensembl chr 6:83,210,402...83,431,051
JBrowse link
G MED11 mediator complex subunit 11 increases expression EXP Amiodarone results in increased expression of MED11 mRNA CTD PMID:19774075 NCBI chr17:4,731,428...4,733,607
Ensembl chr17:4,731,428...4,733,608
JBrowse link
G MEF2C myocyte enhancer factor 2C increases expression EXP Amiodarone results in increased expression of MEF2C mRNA CTD PMID:19774075 NCBI chr 5:88,717,117...88,904,105
Ensembl chr 5:88,717,117...88,904,257
JBrowse link
G MFHAS1 multif