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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:ambenonium chloride
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Accession:CHEBI:2628 term browser browse the term
Definition:A symmetrical oxalamide-based bis-quaternary ammonium salt having ethyl and 2-chlorobenzyl groups attached to the nitrogens.
Synonyms:exact_synonym: 2,2'-[(1,2-dioxoethane-1,2-diyl)diimino]bis[N-(2-chlorobenzyl)-N,N-diethylethanaminium] dichloride
 related_synonym: (Oxalylbis(iminoethylene))bis((o-chlorobenzyl)diethylammonium) dichloride;   Ambenonium dichloride;   Ambestigmin chloride;   Chlorure d'ambenonium;   Cloruro de ambenonio;   Formula=C28H42Cl2N4O2.2Cl;   Formula=C28H42Cl4N4O2;   InChI=1S/C28H40Cl2N4O2.2ClH/c1-5-33(6-2,21-23-13-9-11-15-25(23)29)19-17-31-27(35)28(36)32-18-20-34(7-3,8-4)22-24-14-10-12-16-26(24)30;;/h9-16H,5-8,17-22H2,1-4H3;2*1H;   InChIKey=DXUUXWKFVDVHIK-UHFFFAOYSA-N;   N,N'-Bis(2-diethylaminoethyl)oxamide bis(2-chlorobenzyl chloride);   SMILES=[Cl-].[Cl-].CC[N+](CC)(CCNC(=O)C(=O)NCC[N+](CC)(CC)Cc1ccccc1Cl)Cc1ccccc1Cl;   ambenonii chloridum
 xref: Beilstein:7563564;   CAS:115-79-7;   DrugBank:DB01122;   KEGG:D01001
 xref_mesh: MESH:D000549
 xref: Patent:DE1024517


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ambenonium chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO Ambenonium Chloride results in decreased activity of ACHE protein CTD PMID:33844597 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G App amyloid beta precursor protein affects cleavage EXP Ambenonium Chloride affects the cleavage of APP protein CTD PMID:11099780 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
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  CHEBI ontology 19880
    role 19850
      biological role 19848
        pharmacological role 19080
          neurotransmitter agent 16797
            ambenonium chloride 2
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Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    main group molecular entity 19817
                      s-block molecular entity 19653
                        hydrogen molecular entity 19634
                          hydrides 19144
                            inorganic hydride 18161
                              pnictogen hydride 18151
                                nitrogen hydride 18064
                                  ammonium 8310
                                    ammonium ion derivative 8305
                                      ammonium compound 5195
                                        organoammonium salt 671
                                          quaternary ammonium salt 553
                                            ambenonium chloride 2
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