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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:polyphosphates
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Accession:CHEBI:26197 term browser browse the term
Definition:Any phosphate that is a salt or an ester of polyphosphoric acid or its chalcogen analogues.
Synonyms:xref_mesh: MESH:D011122
 xref: wikipedia.en:Polyphosphate


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polyphosphates term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F12 coagulation factor XII decreases response to substance ISO F12 gene mutant form results in decreased susceptibility to Polyphosphates CTD PMID:25339356 NCBI chr17:9,212,819...9,220,664
Ensembl chr17:9,212,819...9,220,664 		JBrowse link
G Gpt glutamic--pyruvic transaminase increases expression
multiple interactions 		ISO Polyphosphates results in increased expression of GPT protein
dabrafenib inhibits the reaction [Polyphosphates results in increased expression of GPT protein]
Diketopiperazines inhibits the reaction [Polyphosphates results in increased expression of GPT protein] 		CTD PMID:27458080 PMID:27481191 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
increases expression 		ISO dabrafenib inhibits the reaction [Polyphosphates results in increased expression of ICAM1 mRNA]; dabrafenib inhibits the reaction [Polyphosphates results in increased expression of ICAM1 protein]; Diketopiperazines inhibits the reaction [Polyphosphates results in increased expression of ICAM1 mRNA]; Diketopiperazines inhibits the reaction [Polyphosphates results in increased expression of ICAM1 protein]
Polyphosphates results in increased expression of ICAM1 mRNA; Polyphosphates results in increased expression of ICAM1 protein 		CTD PMID:27458080 PMID:27481191 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Il10 interleukin 10 increases secretion ISO Polyphosphates results in increased secretion of IL10 protein CTD PMID:27458080 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il4 interleukin 4 increases secretion ISO Polyphosphates results in increased secretion of IL4 protein CTD PMID:27458080 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases secretion 		ISO apigenin-6,8-di-C-glycopyranoside inhibits the reaction [Polyphosphates results in increased secretion of IL6 protein]; dabrafenib inhibits the reaction [Polyphosphates results in increased secretion of IL6 protein]; Diketopiperazines inhibits the reaction [Polyphosphates results in increased secretion of IL6 protein]; scolymoside inhibits the reaction [Polyphosphates results in increased secretion of IL6 protein] CTD PMID:26621502 PMID:27458080 PMID:27481191 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Inpp5a inositol polyphosphate-5-phosphatase A multiple interactions ISO Polyphosphates binds to and results in decreased activity of INPP5A protein; Polyphosphates inhibits the reaction [INPP5A protein results in increased metabolism of Inositol 1,4,5-Trisphosphate] CTD PMID:18574825 NCBI chr 1:203,619,676...203,810,035
Ensembl chr 1:203,619,637...203,810,028 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases activity
increases phosphorylation 		ISO dabrafenib inhibits the reaction [Polyphosphates results in increased phosphorylation of MAPK1 protein]; Diketopiperazines inhibits the reaction [Polyphosphates results in increased activity of MAPK1 protein] CTD PMID:27458080 PMID:27481191 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases activity
increases phosphorylation 		ISO dabrafenib inhibits the reaction [Polyphosphates results in increased phosphorylation of MAPK3 protein]; Diketopiperazines inhibits the reaction [Polyphosphates results in increased activity of MAPK3 protein] CTD PMID:27458080 PMID:27481191 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases activity 		ISO dabrafenib inhibits the reaction [Polyphosphates results in increased activity of RELA protein]; Diketopiperazines inhibits the reaction [Polyphosphates results in increased activity of RELA protein] CTD PMID:27458080 PMID:27481191 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Sele selectin E multiple interactions
increases expression 		ISO dabrafenib inhibits the reaction [Polyphosphates results in increased expression of SELE mRNA]; dabrafenib inhibits the reaction [Polyphosphates results in increased expression of SELE protein]; Diketopiperazines inhibits the reaction [Polyphosphates results in increased expression of SELE mRNA]; Diketopiperazines inhibits the reaction [Polyphosphates results in increased expression of SELE protein]
Polyphosphates results in increased expression of SELE mRNA; Polyphosphates results in increased expression of SELE protein 		CTD PMID:27458080 PMID:27481191 NCBI chr13:78,935,997...78,945,905
Ensembl chr13:78,936,036...78,945,903 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
increases secretion 		ISO apigenin-6,8-di-C-glycopyranoside inhibits the reaction [Polyphosphates results in increased secretion of TNF protein]; dabrafenib inhibits the reaction [Polyphosphates results in increased expression of TNF protein]; Diketopiperazines inhibits the reaction [Polyphosphates results in increased expression of TNF protein]; scolymoside inhibits the reaction [Polyphosphates results in increased secretion of TNF protein] CTD PMID:26621502 PMID:27458080 PMID:27481191 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions
increases expression 		ISO dabrafenib inhibits the reaction [Polyphosphates results in increased expression of VCAM1 mRNA]; dabrafenib inhibits the reaction [Polyphosphates results in increased expression of VCAM1 protein]; Diketopiperazines inhibits the reaction [Polyphosphates results in increased expression of VCAM1 mRNA]; Diketopiperazines inhibits the reaction [Polyphosphates results in increased expression of VCAM1 protein]
Polyphosphates results in increased expression of VCAM1 mRNA; Polyphosphates results in increased expression of VCAM1 protein 		CTD PMID:27458080 PMID:27481191 NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:206,723,044...206,742,801 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20874
    chemical entity 20872
      molecular entity 20871
        polyatomic entity 20745
          heteroatomic molecular entity 20606
            oxoacid derivative 16322
              phosphorus oxoacid derivative 14118
                phosphoric acid derivative 13866
                  phosphate 13865
                    polyphosphates 13
Path 2
Term Annotations click to browse term
  CHEBI ontology 20874
    subatomic particle 20883
      composite particle 20883
        hadron 20872
          baryon 20883
            nucleon 20872
              atomic nucleus 20883
                atom 20872
                  main group element atom 20796
                    p-block element atom 20796
                      pnictogen 19695
                        phosphorus atom 14760
                          phosphorus molecular entity 14760
                            phosphorus oxoacids and derivatives 14745
                              phosphorus oxoacid derivative 14118
                                phosphoric acid derivative 13866
                                  phosphate 13865
                                    polyphosphates 13
paths to the root