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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:phenanthrenes
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Accession:CHEBI:25961 term browser browse the term
Definition:Any benzenoid aromatic compound that consists of a phenanthrene skeleton and its substituted derivatives thereof.
Synonyms:alt_id: MESH:D010616
 xref_mesh: MESH:D010616


show annotations for term's descendants           Sort by:
phenanthrenes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO Phenanthrenes analog results in increased expression of CYP1A1 protein CTD PMID:19365803 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO Phenanthrenes analog results in increased expression of CYP1B1 protein CTD PMID:19365803 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 affects binding
multiple interactions		 ISO Phenanthrenes analog binds to CYP2A13 protein
[NADP co-treated with CYP2A13 protein] results in increased oxidation of Phenanthrenes analog		 CTD PMID:27137136 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887 		JBrowse link
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D affects response to substance ISO GRIN2D protein affects the susceptibility to Phenanthrenes CTD PMID:19911010 NCBI chr 1:96,306,871...96,346,994
Ensembl chr 1:96,308,365...96,344,793 		JBrowse link
(9R,10S)-9,10-epoxy-9,10-dihydrophenanthrene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ephx1 epoxide hydrolase 1 increases metabolic processing ISO EPHX1 protein mutant form results in increased metabolism of 9,10-epoxy-9,10-dihydrophenanthrene CTD PMID:26838043 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
1-hydroxy-1-norresistomycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO 1-hydroxy-1-norresistomycin results in increased expression of BAX protein CTD PMID:29596799 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Casp3 caspase 3 increases expression ISO 1-hydroxy-1-norresistomycin results in increased expression of CASP3 mRNA; 1-hydroxy-1-norresistomycin results in increased expression of CASP3 protein CTD PMID:29596799 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 increases expression ISO 1-hydroxy-1-norresistomycin results in increased expression of CASP9 mRNA; 1-hydroxy-1-norresistomycin results in increased expression of CASP9 protein CTD PMID:29596799 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO 1-hydroxy-1-norresistomycin results in increased expression of CDKN1A mRNA; 1-hydroxy-1-norresistomycin results in increased expression of CDKN1A protein CTD PMID:29596799 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression ISO 1-hydroxy-1-norresistomycin results in decreased expression of MMP2 mRNA; 1-hydroxy-1-norresistomycin results in decreased expression of MMP2 protein CTD PMID:29596799 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression ISO 1-hydroxy-1-norresistomycin results in decreased expression of MMP9 mRNA; 1-hydroxy-1-norresistomycin results in decreased expression of MMP9 protein CTD PMID:29596799 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Smim10l2a small integral membrane protein 10 like 2A increases expression ISO 1-hydroxy-1-norresistomycin results in increased expression of SMIM10L2A mRNA CTD PMID:29596799 NCBI chr  X:134,151,325...134,154,647 JBrowse link
G Tnf tumor necrosis factor decreases expression ISO 1-hydroxy-1-norresistomycin results in decreased expression of TNF mRNA CTD PMID:29596799 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tp53 tumor protein p53 increases expression ISO 1-hydroxy-1-norresistomycin results in increased expression of TP53 mRNA; 1-hydroxy-1-norresistomycin results in increased expression of TP53 protein CTD PMID:29596799 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
1-methylphenanthrene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of A2M mRNA CTD PMID:17690111 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786 		JBrowse link
G Ahr aryl hydrocarbon receptor increases activity
multiple interactions		 EXP 1-methylphenanthrene results in increased activity of AHR protein
[1-methylphenanthrene results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA		 CTD PMID:11339718 PMID:17941746 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Aldob aldolase, fructose-bisphosphate B multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of ALDOB mRNA CTD PMID:17690111 NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116 		JBrowse link
G Amacr alpha-methylacyl-CoA racemase multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of AMACR mRNA CTD PMID:17690111 NCBI chr 2:59,946,158...59,958,255
Ensembl chr 2:59,946,153...59,958,255 		JBrowse link
G Apoc3 apolipoprotein C3 multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of APOC3 mRNA CTD PMID:17690111 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583 		JBrowse link
G Ar androgen receptor multiple interactions EXP 1-methylphenanthrene inhibits the reaction [Metribolone binds to AR protein] CTD PMID:3695475 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of CDKN1A mRNA CTD PMID:17690111 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Ceacam6 CEA cell adhesion molecule 6 multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of CEACAM6 mRNA CTD PMID:17690111 NCBI chr 1:80,416,531...80,434,668
Ensembl chr 1:80,416,531...80,434,668 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
affects expression
multiple interactions		 EXP
ISO		 1-methylphenanthrene results in increased expression of CYP1A1 protein
1-methylphenanthrene affects the expression of CYP1A1 mRNA
1-methylphenanthrene affects the reaction [Benzo(a)pyrene affects the expression of CYP1A1 mRNA]; [1-methylphenanthrene results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA
[Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of CYP1A1 mRNA		 CTD PMID:11339718 PMID:17690111 PMID:17941746 PMID:27099206 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 affects expression
multiple interactions		 EXP 1-methylphenanthrene affects the expression of CYP1B1 mRNA
1-methylphenanthrene affects the reaction [Benzo(a)pyrene affects the expression of CYP1B1 mRNA]		 CTD PMID:27099206 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Ece1 endothelin converting enzyme 1 multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of ECE1 mRNA CTD PMID:17690111 NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of G6PD mRNA CTD PMID:17690111 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of GADD45A mRNA CTD PMID:17690111 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gck glucokinase multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of GCK mRNA CTD PMID:17690111 NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of HIF1A mRNA CTD PMID:17690111 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of IGF1 mRNA CTD PMID:17690111 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of IGFBP1 mRNA CTD PMID:17690111 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482 		JBrowse link
G Klf6 KLF transcription factor 6 multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of KLF6 mRNA CTD PMID:17690111 NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of MCL1 mRNA CTD PMID:17690111 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Mt1-ps3 metallothionein 1, pseudogene 3 multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of MT1E mRNA CTD PMID:17690111 NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135 		JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of SAT1 mRNA CTD PMID:17690111 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813 		JBrowse link
G Serpina3n serpin family A member 3N multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of SERPINA3 mRNA CTD PMID:17690111 NCBI chr 6:123,323,623...123,331,181
Ensembl chr 6:123,323,629...123,332,433 		JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of SPP1 mRNA CTD PMID:17690111 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Tp53 tumor protein p53 increases phosphorylation EXP 1-methylphenanthrene results in increased phosphorylation of TP53 protein CTD PMID:17941746 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of XRCC1 mRNA CTD PMID:17690111 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
3-Nitrobenzanthrone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi3bp ABI family member 3 binding protein increases expression ISO 3-nitrobenzanthrone results in increased expression of ABI3BP mRNA CTD PMID:34036453 NCBI chr11:43,912,187...44,128,888
Ensembl chr11:43,913,043...44,128,929 		JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of ADAMTS1 mRNA CTD PMID:34036453 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103 		JBrowse link
G Adgra2 adhesion G protein-coupled receptor A2 increases expression ISO 3-nitrobenzanthrone results in increased expression of ADGRA2 mRNA CTD PMID:34036453 NCBI chr16:64,932,964...64,971,433
Ensembl chr16:64,933,315...64,971,483 		JBrowse link
G Adm2 adrenomedullin 2 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of ADM2 mRNA CTD PMID:34036453 NCBI chr 7:120,393,179...120,394,965
Ensembl chr 7:120,393,179...120,396,331 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO 3-nitrobenzanthrone binds to and results in increased activity of AHR protein CTD PMID:28186253 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 multiple interactions
increases reduction		 ISO [AKR1C1 protein results in increased reduction of 3-nitrobenzanthrone] which results in increased chemical synthesis of 3-aminobenzanthrone; [AKR1C1 protein results in increased reduction of 3-nitrobenzanthrone] which results in increased chemical synthesis of N-hydroxy-3-aminobenzanthrone CTD PMID:30406992 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 multiple interactions
increases reduction		 ISO [AKR1C2 protein results in increased reduction of 3-nitrobenzanthrone] which results in increased chemical synthesis of 3-aminobenzanthrone; [AKR1C2 protein results in increased reduction of 3-nitrobenzanthrone] which results in increased chemical synthesis of N-hydroxy-3-aminobenzanthrone CTD PMID:30406992 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases reduction
multiple interactions		 ISO AKR1C3 protein results in increased reduction of 3-nitrobenzanthrone
[AKR1C3 protein results in increased reduction of 3-nitrobenzanthrone] which results in increased chemical synthesis of 3-aminobenzanthrone; [AKR1C3 protein results in increased reduction of 3-nitrobenzanthrone] which results in increased chemical synthesis of N-hydroxy-3-aminobenzanthrone		 CTD PMID:30406992 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO 3-nitrobenzanthrone results in increased expression of and results in increased phosphorylation of AKT1 protein; EREG protein affects the reaction [3-nitrobenzanthrone results in increased phosphorylation of AKT1 protein] CTD PMID:34036453 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Ang angiogenin decreases expression ISO 3-nitrobenzanthrone results in decreased expression of ANG mRNA CTD PMID:34036453 NCBI chr15:24,312,711...24,323,361 JBrowse link
G Apoe apolipoprotein E increases expression ISO 3-nitrobenzanthrone results in increased expression of APOE mRNA CTD PMID:34036453 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Arap2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of ARAP2 mRNA CTD PMID:34036453 NCBI chr14:46,717,657...46,917,326
Ensembl chr14:46,718,760...46,917,154 		JBrowse link
G Areg amphiregulin increases expression ISO 3-nitrobenzanthrone results in increased expression of AREG mRNA CTD PMID:34036453 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535 		JBrowse link
G Bicc1 BicC family RNA binding protein 1 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of BICC1 mRNA CTD PMID:34036453 NCBI chr20:17,449,639...17,686,775
Ensembl chr20:17,449,560...17,686,776 		JBrowse link
G Bmp4 bone morphogenetic protein 4 increases expression ISO 3-nitrobenzanthrone results in increased expression of BMP4 mRNA CTD PMID:34036453 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Bmper BMP-binding endothelial regulator increases expression ISO 3-nitrobenzanthrone results in increased expression of BMPER mRNA CTD PMID:34036453 NCBI chr 8:21,732,225...21,977,261
Ensembl chr 8:21,732,225...21,977,256 		JBrowse link
G Bnc2 basonuclin zinc finger protein 2 increases expression ISO 3-nitrobenzanthrone results in increased expression of BNC2 mRNA CTD PMID:34036453 NCBI chr 5:98,679,071...99,016,044
Ensembl chr 5:98,687,410...99,079,426 		JBrowse link
G Btg1 BTG anti-proliferation factor 1 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of BTG1 mRNA CTD PMID:34036453 NCBI chr 7:31,341,391...31,343,649
Ensembl chr 7:31,341,027...31,343,649 		JBrowse link
G Cav1 caveolin 1 increases expression ISO 3-nitrobenzanthrone results in increased expression of CAV1 mRNA CTD PMID:34036453 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Ccbe1 collagen and calcium binding EGF domains 1 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of CCBE1 mRNA CTD PMID:34036453 NCBI chr18:59,579,851...59,823,977
Ensembl chr18:59,580,768...59,824,400 		JBrowse link
G Cd24 CD24 molecule increases expression ISO 3-nitrobenzanthrone results in increased expression of CD24 mRNA CTD PMID:34036453 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662 		JBrowse link
G Cd34 CD34 molecule affects expression ISO 3-nitrobenzanthrone affects the expression of CD34 mRNA CTD PMID:34036453 NCBI chr13:106,480,313...106,500,844
Ensembl chr13:106,480,043...106,499,832 		JBrowse link
G Cdh1 cadherin 1 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of CDH1 mRNA; 3-nitrobenzanthrone results in decreased expression of CDH1 protein CTD PMID:34036453 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdk14 cyclin-dependent kinase 14 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of CDK14 mRNA CTD PMID:34036453 NCBI chr 4:28,666,416...29,258,865
Ensembl chr 4:28,666,843...29,258,861 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO 3-nitrobenzanthrone results in increased expression of CDKN1A protein CTD PMID:25230394 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Chrdl1 chordin-like 1 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of CHRDL1 mRNA CTD PMID:34036453 NCBI chr  X:106,889,125...106,992,937
Ensembl chr  X:106,889,125...106,992,921 		JBrowse link
G Cldn3 claudin 3 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of CLDN3 mRNA CTD PMID:34036453 NCBI chr12:21,708,538...21,710,010
Ensembl chr12:21,708,398...21,711,001 		JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain decreases expression ISO 3-nitrobenzanthrone results in decreased expression of COL18A1 mRNA CTD PMID:34036453 NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593 		JBrowse link
G Col5a2 collagen type V alpha 2 chain increases expression ISO 3-nitrobenzanthrone results in increased expression of COL5A2 mRNA CTD PMID:34036453 NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154 		JBrowse link
G Col6a1 collagen type VI alpha 1 chain affects expression ISO 3-nitrobenzanthrone affects the expression of COL6A1 mRNA CTD PMID:34036453 NCBI chr20:11,906,105...11,924,599
Ensembl chr20:11,905,957...11,924,597 		JBrowse link
G Ctnnb1 catenin beta 1 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of CTNNB1 mRNA CTD PMID:34036453 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 increases expression ISO 3-nitrobenzanthrone results in increased expression of CXCL14 mRNA CTD PMID:19879285 NCBI chr17:8,317,930...8,325,956
Ensembl chr17:8,317,933...8,324,839 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of CXCR4 mRNA CTD PMID:34036453 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression		 ISO CYP1A1 protein affects the reaction [3-nitrobenzanthrone results in increased abundance of Reactive Oxygen Species]
3-nitrobenzanthrone results in increased expression of CYP1A1 mRNA		 CTD PMID:17477947 PMID:25230394 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO 3-nitrobenzanthrone results in increased expression of CYP1B1 mRNA CTD PMID:34036453 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 affects expression ISO 3-nitrobenzanthrone affects the expression of DDR2 mRNA CTD PMID:34036453 NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363 		JBrowse link
G Dsc2 desmocollin 2 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of DSC2 mRNA CTD PMID:34036453 NCBI chr18:11,450,392...11,482,476
Ensembl chr18:11,450,390...11,482,392 		JBrowse link
G Ecm1 extracellular matrix protein 1 affects expression ISO 3-nitrobenzanthrone affects the expression of ECM1 mRNA CTD PMID:34036453 NCBI chr 2:183,287,491...183,292,729
Ensembl chr 2:183,287,322...183,292,671 		JBrowse link
G Epcam epithelial cell adhesion molecule decreases expression ISO 3-nitrobenzanthrone results in decreased expression of EPCAM mRNA CTD PMID:34036453 NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127 		JBrowse link
G Eps8l1 EPS8-like 1 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of EPS8L1 mRNA CTD PMID:34036453 NCBI chr 1:69,343,202...69,359,778
Ensembl chr 1:69,344,243...69,363,524 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of ERBB2 mRNA CTD PMID:34036453 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Ereg epiregulin increases expression
multiple interactions		 ISO 3-nitrobenzanthrone results in increased expression of EREG mRNA; 3-nitrobenzanthrone results in increased expression of EREG protein
EREG protein affects the reaction [3-nitrobenzanthrone results in increased expression of SOX9 protein]; EREG protein affects the reaction [3-nitrobenzanthrone results in increased expression of TWIST2 protein]; EREG protein affects the reaction [3-nitrobenzanthrone results in increased phosphorylation of AKT1 protein]; EREG protein affects the reaction [3-nitrobenzanthrone results in increased phosphorylation of MAPK1 protein]; EREG protein affects the reaction [3-nitrobenzanthrone results in increased phosphorylation of MAPK3 protein]; EREG protein affects the reaction [3-nitrobenzanthrone results in increased phosphorylation of STAT3 protein]		 CTD PMID:34036453 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G Etv4 ETS variant transcription factor 4 increases expression ISO 3-nitrobenzanthrone results in increased expression of ETV4 mRNA CTD PMID:34036453 NCBI chr10:86,706,749...86,721,974
Ensembl chr10:86,706,749...86,721,974 		JBrowse link
G F11r F11 receptor decreases expression ISO 3-nitrobenzanthrone results in decreased expression of F11R mRNA CTD PMID:34036453 NCBI chr13:83,873,797...83,897,388
Ensembl chr13:83,873,797...83,897,402 		JBrowse link
G Fbln1 fibulin 1 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of FBLN1 mRNA CTD PMID:34036453 NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075 		JBrowse link
G Fbln5 fibulin 5 increases expression ISO 3-nitrobenzanthrone results in increased expression of FBLN5 mRNA CTD PMID:34036453 NCBI chr 6:120,899,219...120,977,829
Ensembl chr 6:120,899,224...120,977,755 		JBrowse link
G Fgf18 fibroblast growth factor 18 affects expression ISO 3-nitrobenzanthrone affects the expression of FGF18 mRNA CTD PMID:34036453 NCBI chr10:17,706,011...17,737,702
Ensembl chr10:17,706,174...17,736,818 		JBrowse link
G Fgf2 fibroblast growth factor 2 increases expression ISO 3-nitrobenzanthrone results in increased expression of FGF2 mRNA CTD PMID:34036453 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fgf9 fibroblast growth factor 9 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of FGF9 mRNA CTD PMID:34036453 NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 increases expression ISO 3-nitrobenzanthrone results in increased expression of FGFR2 mRNA CTD PMID:34036453 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Flt4 Fms related receptor tyrosine kinase 4 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of FLT4 mRNA CTD PMID:34036453 NCBI chr10:33,913,725...33,954,770
Ensembl chr10:33,913,608...33,954,770 		JBrowse link
G Foxo4 forkhead box O4 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of FOXO4 mRNA CTD PMID:34036453 NCBI chr  X:66,385,241...66,392,115
Ensembl chr  X:66,385,558...66,392,115 		JBrowse link
G Fst follistatin increases expression ISO 3-nitrobenzanthrone results in increased expression of FST mRNA CTD PMID:34036453 NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571 		JBrowse link
G Gdf6 growth differentiation factor 6 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of GDF6 mRNA CTD PMID:34036453 NCBI chr 5:22,996,246...23,012,567
Ensembl chr 5:22,996,246...23,012,567 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist increases expression ISO 3-nitrobenzanthrone results in increased expression of GREM1 mRNA CTD PMID:34036453 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082 		JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 increases expression ISO 3-nitrobenzanthrone results in increased expression of HIPK2 mRNA CTD PMID:34036453 NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223 		JBrowse link
G Hoxb3 homeo box B3 increases expression ISO 3-nitrobenzanthrone results in increased expression of HOXB3 mRNA CTD PMID:34036453 NCBI chr10:81,258,739...81,314,134
Ensembl chr10:81,299,357...81,313,107 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 multiple interactions ISO [NAT2 protein co-treated with 3-nitrobenzanthrone] results in increased mutagenesis of HPRT1 gene; [SULT1A1 protein co-treated with 3-nitrobenzanthrone] results in increased mutagenesis of HPRT1 gene CTD PMID:17483118 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154 		JBrowse link
G Id2 inhibitor of DNA binding 2 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of ID2 mRNA CTD PMID:34036453 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 increases expression ISO 3-nitrobenzanthrone results in increased expression of IGFBP4 mRNA CTD PMID:34036453 NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225 		JBrowse link
G Il15 interleukin 15 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of IL15 mRNA CTD PMID:34036453 NCBI chr19:25,640,025...25,706,818
Ensembl chr19:25,640,251...25,706,820 		JBrowse link
G Il18 interleukin 18 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of IL18 mRNA CTD PMID:34036453 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1b interleukin 1 beta affects expression ISO 3-nitrobenzanthrone affects the expression of IL1B mRNA CTD PMID:34036453 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 increases expression
increases secretion
multiple interactions		 ISO 3-nitrobenzanthrone results in increased expression of IL6 mRNA
3-nitrobenzanthrone results in increased secretion of IL6 protein
IL6 protein affects the reaction [3-nitrobenzanthrone results in increased phosphorylation of MAPK1 protein]; IL6 protein affects the reaction [3-nitrobenzanthrone results in increased phosphorylation of MAPK3 protein]; IL6 protein affects the reaction [3-nitrobenzanthrone results in increased phosphorylation of STAT3 protein]		 CTD PMID:34036453 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Inhba inhibin subunit beta A increases expression ISO 3-nitrobenzanthrone results in increased expression of INHBA mRNA CTD PMID:34036453 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982 		JBrowse link
G Irf6 interferon regulatory factor 6 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of IRF6 mRNA CTD PMID:34036453 NCBI chr13:104,672,179...104,691,386
Ensembl chr13:104,672,179...104,691,386 		JBrowse link
G Isl1 ISL LIM homeobox 1 affects expression ISO 3-nitrobenzanthrone affects the expression of ISL1 mRNA CTD PMID:34036453 NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584 		JBrowse link
G Itga1 integrin subunit alpha 1 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of ITGA1 mRNA CTD PMID:34036453 NCBI chr 2:46,646,125...46,812,237
Ensembl chr 2:46,653,193...46,812,238 		JBrowse link
G Itgb1bp1 integrin subunit beta 1 binding protein 1 increases expression ISO 3-nitrobenzanthrone results in increased expression of ITGB1BP1 mRNA CTD PMID:34036453 NCBI chr 6:40,820,693...40,836,074
Ensembl chr 6:40,821,339...40,836,037 		JBrowse link
G Itgb3 integrin subunit beta 3 affects expression ISO 3-nitrobenzanthrone affects the expression of ITGB3 mRNA CTD PMID:34036453 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
G Itm2a integral membrane protein 2A affects expression ISO 3-nitrobenzanthrone affects the expression of ITM2A mRNA CTD PMID:34036453 NCBI chr  X:72,486,383...72,492,344
Ensembl chr  X:72,486,381...72,492,363 		JBrowse link
G Jam2 junctional adhesion molecule 2 affects expression ISO 3-nitrobenzanthrone affects the expression of JAM2 mRNA CTD PMID:34036453 NCBI chr11:23,830,820...23,880,071
Ensembl chr11:23,831,106...23,880,063 		JBrowse link
G Jcad junctional cadherin 5 associated increases expression ISO 3-nitrobenzanthrone results in increased expression of JCAD mRNA CTD PMID:34036453 NCBI chr17:53,089,382...53,130,996
Ensembl chr17:53,089,382...53,130,967 		JBrowse link
G Krt7 keratin 7 affects expression ISO 3-nitrobenzanthrone affects the expression of KRT7 mRNA CTD PMID:34036453 NCBI chr 7:132,528,881...132,545,052
Ensembl chr 7:132,528,895...132,545,052 		JBrowse link
G Lad1 ladinin 1 increases expression ISO 3-nitrobenzanthrone results in increased expression of LAD1 mRNA CTD PMID:34036453 NCBI chr13:47,249,605...47,263,967
Ensembl chr13:47,249,605...47,263,967 		JBrowse link
G Llgl2 LLGL scribble cell polarity complex component 2 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of LLGL2 mRNA CTD PMID:34036453 NCBI chr10:101,050,978...101,086,527
Ensembl chr10:101,051,408...101,086,525 		JBrowse link
G Lum lumican decreases expression ISO 3-nitrobenzanthrone results in decreased expression of LUM mRNA CTD PMID:34036453 NCBI chr 7:32,358,990...32,365,794
Ensembl chr 7:32,358,614...32,365,793 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions		 ISO 3-nitrobenzanthrone results in increased phosphorylation of MAPK1 protein
EREG protein affects the reaction [3-nitrobenzanthrone results in increased phosphorylation of MAPK1 protein]; IL6 protein affects the reaction [3-nitrobenzanthrone results in increased phosphorylation of MAPK1 protein]		 CTD PMID:34036453 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions		 ISO 3-nitrobenzanthrone results in increased phosphorylation of MAPK3 protein
EREG protein affects the reaction [3-nitrobenzanthrone results in increased phosphorylation of MAPK3 protein]; IL6 protein affects the reaction [3-nitrobenzanthrone results in increased phosphorylation of MAPK3 protein]		 CTD PMID:34036453 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase increases expression ISO 3-nitrobenzanthrone results in increased expression of MET mRNA; 3-nitrobenzanthrone results in increased expression of MET protein CTD PMID:34036453 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of MMP2 mRNA CTD PMID:34036453 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Myo1d myosin ID affects expression ISO 3-nitrobenzanthrone affects the expression of MYO1D mRNA CTD PMID:34036453 NCBI chr10:65,489,153...65,765,812
Ensembl chr10:65,489,154...65,766,349 		JBrowse link
G Myo5c myosin VC decreases expression ISO 3-nitrobenzanthrone results in decreased expression of MYO5C mRNA CTD PMID:34036453 NCBI chr 8:75,989,497...76,066,485
Ensembl chr 8:75,989,528...76,066,483 		JBrowse link
G Nat1 N-acetyltransferase 1 multiple interactions
increases activity		 ISO [NQO1 protein co-treated with NADP co-treated with Acetyl Coenzyme A co-treated with NAT1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone
NAT1 protein results in increased activity of 3-nitrobenzanthrone		 CTD PMID:15805261 PMID:20545351 NCBI chr16:22,218,217...22,238,516
Ensembl chr16:22,208,194...22,238,520 		JBrowse link
G Nat2 N-acetyltransferase 2 multiple interactions
increases response to substance
increases activity		 ISO [NAT2 protein co-treated with 3-nitrobenzanthrone] results in increased mutagenesis of HPRT1 gene; [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[NQO1 protein co-treated with NADP] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone]; [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[SULT1A2 protein co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone]
NAT2 protein results in increased susceptibility to 3-nitrobenzanthrone
NAT2 protein results in increased activity of 3-nitrobenzanthrone		 CTD PMID:15805261 PMID:17483118 PMID:20545351 NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520 		JBrowse link
G Ndrg1 N-myc downstream regulated 1 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of NDRG1 mRNA CTD PMID:34036453 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880 		JBrowse link
G Nf1 neurofibromin 1 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of NF1 mRNA CTD PMID:34036453 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 affects metabolic processing
multiple interactions
affects response to substance		 ISO NFE2L2 protein affects the metabolism of 3-nitrobenzanthrone
[NFE2L2 protein affects the metabolism of 3-nitrobenzanthrone] which affects the abundance of 3-aminobenzanthrone
NFE2L2 protein affects the susceptibility to 3-nitrobenzanthrone		 CTD PMID:31746589 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
increases reduction
multiple interactions
affects binding
increases metabolic processing
increases activity		 ISO 3-nitrobenzanthrone results in increased expression of NQO1 mRNA
NQO1 protein results in increased reduction of 3-nitrobenzanthrone
[NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[NQO1 protein co-treated with NADP] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone]; [NQO1 protein co-treated with NADP co-treated with Acetyl Coenzyme A co-treated with NAT1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone; [NQO1 protein co-treated with NADP co-treated with Phosphoadenosine Phosphosulfate co-treated with SULT1A1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone; [NQO1 protein co-treated with NADP] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone; [NQO1 protein results in increased reduction of 3-nitrobenzanthrone] which results in increased chemical synthesis of 3-aminobenzanthrone; [NQO1 protein results in increased reduction of 3-nitrobenzanthrone] which results in increased chemical synthesis of N-hydroxy-3-aminobenzanthrone
3-nitrobenzanthrone binds to NQO1 protein
NQO1 protein results in increased metabolism of 3-nitrobenzanthrone
NQO1 protein results in increased activity of 3-nitrobenzanthrone		 CTD PMID:15805261 PMID:20545351 PMID:25230394 PMID:28922594 PMID:30406992 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 increases expression ISO 3-nitrobenzanthrone results in increased expression of NR4A1 mRNA CTD PMID:34036453 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297 		JBrowse link
G Nrp1 neuropilin 1 increases expression ISO 3-nitrobenzanthrone results in increased expression of NRP1 mRNA CTD PMID:34036453 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633 		JBrowse link
G Nrp2 neuropilin 2 affects expression ISO 3-nitrobenzanthrone affects the expression of NRP2 mRNA CTD PMID:34036453 NCBI chr 9:64,122,815...64,238,007
Ensembl chr 9:64,123,132...64,237,958 		JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A decreases expression ISO 3-nitrobenzanthrone results in decreased expression of OAS1 mRNA CTD PMID:34036453 NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517 		JBrowse link
G Pdpn podoplanin decreases expression ISO 3-nitrobenzanthrone results in decreased expression of PDPN mRNA CTD PMID:34036453 NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656 		JBrowse link
G Pkn1 protein kinase N1 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of PKN1 mRNA CTD PMID:34036453 NCBI chr19:24,442,130...24,470,107
Ensembl chr19:24,442,122...24,470,107 		JBrowse link
G Plxnd1 plexin D1 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of PLXND1 mRNA CTD PMID:34036453 NCBI chr 4:149,002,786...149,043,097
Ensembl chr 4:149,002,784...149,043,244 		JBrowse link
G Pmp22 peripheral myelin protein 22 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of PMP22 mRNA CTD PMID:34036453 NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714 		JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions ISO [POR protein co-treated with NADP] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone; POR protein results in increased activity of and results in increased reduction of 3-nitrobenzanthrone CTD PMID:20545351 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
G Ppfibp2 PPFIA binding protein 2 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of PPFIBP2 mRNA CTD PMID:34036453 NCBI chr 1:161,504,774...161,687,339
Ensembl chr 1:161,504,890...161,655,212 		JBrowse link
G Ppl periplakin decreases expression ISO 3-nitrobenzanthrone results in decreased expression of PPL mRNA CTD PMID:34036453 NCBI chr10:10,450,919...10,496,575
Ensembl chr10:10,450,919...10,496,575 		JBrowse link
G Ptx3 pentraxin 3 increases expression ISO 3-nitrobenzanthrone results in increased expression of PTX3 mRNA CTD PMID:34036453 NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323 		JBrowse link
G Pycard PYD and CARD domain containing decreases expression ISO 3-nitrobenzanthrone results in decreased expression of PYCARD mRNA CTD PMID:34036453 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Ramp2 receptor activity modifying protein 2 increases expression ISO 3-nitrobenzanthrone results in increased expression of RAMP2 mRNA CTD PMID:34036453 NCBI chr10:86,187,366...86,190,692
Ensembl chr10:86,188,812...86,231,829 		JBrowse link
G RT1-Hb-ps1 RT1 class II, locus Hb, pseudogene 1 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of HLA-DPB1 mRNA CTD PMID:34036453 NCBI chr20:4,775,598...4,779,590
Ensembl chr20:4,774,650...4,780,618 		JBrowse link
G Sema3e semaphorin 3E decreases expression ISO 3-nitrobenzanthrone results in decreased expression of SEMA3E mRNA CTD PMID:34036453 NCBI chr 4:20,297,534...20,555,287
Ensembl chr 4:20,299,718...20,555,229 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 increases expression ISO 3-nitrobenzanthrone results in increased expression of SFRP1 mRNA CTD PMID:34036453 NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286 		JBrowse link
G Slc37a1 solute carrier family 37 member 1 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of SLC37A1 mRNA CTD PMID:34036453 NCBI chr20:9,360,501...9,433,895
Ensembl chr20:9,378,836...9,433,892 		JBrowse link
G Slit2 slit guidance ligand 2 increases expression ISO 3-nitrobenzanthrone results in increased expression of SLIT2 mRNA CTD PMID:34036453 NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948 		JBrowse link
G Snai2 snail family transcriptional repressor 2 increases expression ISO 3-nitrobenzanthrone results in increased expression of SNAI2 mRNA; 3-nitrobenzanthrone results in increased expression of SNAI2 protein CTD PMID:34036453 NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200 		JBrowse link
G Snai3 snail family transcriptional repressor 3 increases expression ISO 3-nitrobenzanthrone results in increased expression of SNAI3 mRNA CTD PMID:34036453 NCBI chr19:50,516,771...50,529,295
Ensembl chr19:50,516,771...50,523,486 		JBrowse link
G Sox9 SRY-box transcription factor 9 increases expression
multiple interactions		 ISO 3-nitrobenzanthrone results in increased expression of SOX9 mRNA; 3-nitrobenzanthrone results in increased expression of SOX9 protein
EREG protein affects the reaction [3-nitrobenzanthrone results in increased expression of SOX9 protein]		 CTD PMID:34036453 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Spint1 serine peptidase inhibitor, Kunitz type 1 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of SPINT1 mRNA CTD PMID:34036453 NCBI chr 3:106,231,082...106,244,121
Ensembl chr 3:106,231,444...106,244,119 		JBrowse link
G Spock3 SPARC/osteonectin, cwcv and kazal like domains proteoglycan 3 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of SPOCK3 mRNA CTD PMID:34036453 NCBI chr16:26,382,895...26,815,943
Ensembl chr16:26,383,383...26,815,205 		JBrowse link
G Srf serum response factor increases expression ISO 3-nitrobenzanthrone results in increased expression of SRF mRNA CTD PMID:34036453 NCBI chr 9:14,426,453...14,435,734
Ensembl chr 9:14,426,472...14,435,733 		JBrowse link
G Srgn serglycin increases expression ISO 3-nitrobenzanthrone results in increased expression of SRGN mRNA CTD PMID:34036453 NCBI chr20:30,442,810...30,479,549
Ensembl chr20:30,442,813...30,457,406 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of STAT1 mRNA CTD PMID:34036453 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases phosphorylation
multiple interactions		 ISO 3-nitrobenzanthrone results in increased phosphorylation of STAT3 protein
EREG protein affects the reaction [3-nitrobenzanthrone results in increased phosphorylation of STAT3 protein]; IL6 protein affects the reaction [3-nitrobenzanthrone results in increased phosphorylation of STAT3 protein]		 CTD PMID:34036453 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Sulf1 sulfatase 1 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of SULF1 mRNA CTD PMID:34036453 NCBI chr 5:6,362,894...6,526,174
Ensembl chr 5:6,362,911...6,525,584 		JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 multiple interactions
increases activity
increases response to substance		 ISO [NQO1 protein co-treated with NADP co-treated with Phosphoadenosine Phosphosulfate co-treated with SULT1A1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone; [SULT1A1 protein co-treated with 3-nitrobenzanthrone] results in increased mutagenesis of HPRT1 gene
SULT1A1 protein results in increased activity of 3-nitrobenzanthrone
SULT1A1 protein results in increased susceptibility to 3-nitrobenzanthrone		 CTD PMID:15805261 PMID:17483118 PMID:20545351 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562 		JBrowse link
G Syne1 spectrin repeat containing nuclear envelope protein 1 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of SYNE1 mRNA CTD PMID:34036453 NCBI chr 1:41,512,146...41,983,382
Ensembl chr 1:41,512,030...41,983,322 		JBrowse link
G Tcf4 transcription factor 4 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of TCF4 mRNA CTD PMID:34036453 NCBI chr18:62,941,739...63,288,126
Ensembl chr18:62,943,782...63,284,425 		JBrowse link
G Thbs1 thrombospondin 1 increases expression ISO 3-nitrobenzanthrone results in increased expression of THBS1 mRNA CTD PMID:34036453 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Thbs2 thrombospondin 2 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of THBS2 mRNA CTD PMID:34036453 NCBI chr 1:55,670,394...55,699,789
Ensembl chr 1:55,670,394...55,699,789 		JBrowse link
G Timp4 TIMP metallopeptidase inhibitor 4 affects expression ISO 3-nitrobenzanthrone affects the expression of TIMP4 mRNA CTD PMID:34036453 NCBI chr 4:148,306,021...148,312,558
Ensembl chr 4:148,304,490...148,312,558 		JBrowse link
G Tjp3 tight junction protein 3 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of TJP3 mRNA CTD PMID:34036453 NCBI chr 7:8,427,650...8,446,279
Ensembl chr 7:8,432,811...8,446,279 		JBrowse link
G Tnc tenascin C increases expression ISO 3-nitrobenzanthrone results in increased expression of TNC mRNA CTD PMID:34036453 NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624 		JBrowse link
G Tnfsf12 TNF superfamily member 12 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of TNFSF12 mRNA CTD PMID:34036453 NCBI chr10:54,403,870...54,413,213
Ensembl chr10:54,403,870...54,413,213 		JBrowse link
G Tns1 tensin 1 affects expression ISO 3-nitrobenzanthrone affects the expression of TNS1 mRNA CTD PMID:34036453 NCBI chr 9:75,491,886...75,702,853
Ensembl chr 9:75,495,814...75,703,225 		JBrowse link
G Tom1l1 target of myb1 like 1 membrane trafficking protein decreases expression ISO 3-nitrobenzanthrone results in decreased expression of TOM1L1 mRNA CTD PMID:34036453 NCBI chr10:75,464,577...75,508,304
Ensembl chr10:75,464,577...75,508,250 		JBrowse link
G Tp53 tumor protein p53 decreases expression
increases mutagenesis
increases expression		 ISO 3-nitrobenzanthrone results in decreased expression of TP53 mRNA; 3-nitrobenzanthrone results in decreased expression of TP53 protein
3-nitrobenzanthrone results in increased mutagenesis of TP53 gene
3-nitrobenzanthrone results in increased expression of TRP53 protein		 CTD PMID:18765419 PMID:25230394 PMID:34036453 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 increases expression
affects expression		 ISO 3-nitrobenzanthrone results in increased expression of TWIST1 protein
3-nitrobenzanthrone affects the expression of TWIST1 mRNA		 CTD PMID:34036453 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653 		JBrowse link
G Twist2 twist family bHLH transcription factor 2 multiple interactions
increases expression		 ISO EREG protein affects the reaction [3-nitrobenzanthrone results in increased expression of TWIST2 protein]
3-nitrobenzanthrone results in increased expression of TWIST2 mRNA; 3-nitrobenzanthrone results in increased expression of TWIST2 protein		 CTD PMID:34036453 NCBI chr 9:92,374,740...92,419,222
Ensembl chr 9:92,374,574...92,419,222 		JBrowse link
G Vamp8 vesicle-associated membrane protein 8 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of VAMP8 mRNA CTD PMID:34036453 NCBI chr 4:104,442,383...104,452,884
Ensembl chr 4:104,442,393...104,452,897 		JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 increases expression ISO 3-nitrobenzanthrone results in increased expression of ZEB1 mRNA CTD PMID:34036453 NCBI chr17:51,948,948...52,116,018
Ensembl chr17:51,948,948...52,115,214 		JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 decreases expression ISO 3-nitrobenzanthrone results in decreased expression of ZEB2 mRNA CTD PMID:34036453 NCBI chr 3:29,214,581...29,344,890
Ensembl chr 3:29,218,301...29,345,157 		JBrowse link
3-Nitroperylene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor affects binding EXP 3-nitroperylene binds to AHR protein CTD PMID:6329540 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
7-Benzylidenenaltrexone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Oprm1 opioid receptor, mu 1 multiple interactions ISO [7-benzylidenenaltrexone binds to and results in decreased activity of OPRM1 protein] which affects the localization of Guanosine 5'-O-(3-Thiotriphosphate); [7-benzylidenenaltrexone binds to and results in decreased activity of OPRM1 protein] which results in increased expression of Cyclic AMP CTD PMID:11413242 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
7-Nitrobenz[a]anthracene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO 7-nitrobenzanthracene binds to and results in increased activity of AHR protein CTD PMID:28186253 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO 7-nitrobenzanthracene results in increased expression of CYP1A1 mRNA CTD PMID:12107646 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO 7-nitrobenzanthracene results in increased expression of CYP1A2 mRNA CTD PMID:12107646 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
9,10-epoxy-9,10-dihydrophenanthrene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ephx1 epoxide hydrolase 1 increases metabolic processing ISO EPHX1 protein mutant form results in increased metabolism of 9,10-epoxy-9,10-dihydrophenanthrene CTD PMID:26838043 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
9,10-phenanthroquinone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1a1 aldo-keto reductase family 1 member A1 multiple interactions ISO AKR1A1 protein results in increased reduction of and affects the activity of 9,10-phenanthrenequinone CTD PMID:21910479 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 increases reduction
multiple interactions		 ISO AKR1B1 protein results in increased reduction of 9,10-phenanthrenequinone
AKR1B1 protein results in increased reduction of and affects the activity of 9,10-phenanthrenequinone		 CTD PMID:10510318 PMID:21910479 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases metabolic processing
increases expression		 ISO AKR1B10 protein results in increased metabolism of 9,10-phenanthrenequinone
9,10-phenanthrenequinone results in increased expression of AKR1B10 mRNA		 CTD PMID:24813866 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 increases metabolic processing
multiple interactions
increases reduction		 ISO AKR1C1 protein results in increased metabolism of 9,10-phenanthrenequinone
AKR1C1 protein results in increased reduction of and affects the activity of 9,10-phenanthrenequinone
AKR1C1 protein results in increased reduction of 9,10-phenanthrenequinone		 CTD PMID:17950253 PMID:21851338 PMID:21910479 PMID:23261716 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases metabolic processing
increases reduction
multiple interactions		 ISO AKR1C2 protein results in increased metabolism of 9,10-phenanthrenequinone
AKR1C2 protein results in increased reduction of 9,10-phenanthrenequinone
AKR1C2 protein results in increased reduction of and affects the activity of 9,10-phenanthrenequinone		 CTD PMID:17950253 PMID:21851338 PMID:21910479 PMID:23261716 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases metabolic processing
increases expression
increases reduction
multiple interactions		 ISO AKR1C3 protein results in increased metabolism of 9,10-phenanthrenequinone
9,10-phenanthrenequinone results in increased expression of AKR1C3 protein
AKR1C3 protein results in increased reduction of 9,10-phenanthrenequinone
[AKR1C3 protein results in increased reduction of 9,10-phenanthrenequinone] which results in increased abundance of Superoxides; AKR1C3 protein results in increased reduction of and affects the activity of 9,10-phenanthrenequinone; Indomethacin analog inhibits the reaction [AKR1C3 protein results in increased metabolism of 9,10-phenanthrenequinone]; Indomethacin inhibits the reaction [AKR1C3 protein results in increased metabolism of 9,10-phenanthrenequinone]; N-(4-chlorobenzoyl)melatonin inhibits the reaction [AKR1C3 protein results in increased metabolism of 9,10-phenanthrenequinone]		 CTD PMID:17950253 PMID:19442656 PMID:21851338 PMID:21910479 PMID:23261716 More... NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 increases reduction
multiple interactions
affects reduction		 ISO AKR7A2 protein results in increased reduction of 9,10-phenanthrenequinone
AKR7A2 protein results in increased reduction of and affects the activity of 9,10-phenanthrenequinone
9,10-phenanthrenequinone affects the reduction of AKR7A5 protein		 CTD PMID:10510318 PMID:12604212 PMID:21910479 NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909 		JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 increases reduction
multiple interactions		 EXP
ISO		 AKR7A3 protein results in increased reduction of 9,10-phenanthrenequinone
AKR7A3 protein results in increased reduction of and affects the activity of 9,10-phenanthrenequinone		 CTD PMID:19168568 PMID:21910479 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO 9,10-phenanthrenequinone results in increased expression of BAX protein CTD PMID:29108775 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO 9,10-phenanthrenequinone results in increased expression of BBC3 protein CTD PMID:29108775 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO 9,10-phenanthrenequinone results in decreased expression of BCL2 protein CTD PMID:29108775 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions		 ISO 9,10-phenanthrenequinone results in increased activity of CASP3 protein
Acetylcysteine inhibits the reaction [9,10-phenanthrenequinone results in increased activity of CASP3 protein]		 CTD PMID:25289770 PMID:29108775 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 increases activity
multiple interactions		 ISO 9,10-phenanthrenequinone results in increased activity of CASP9 protein
Acetylcysteine inhibits the reaction [9,10-phenanthrenequinone results in increased activity of CASP9 protein]		 CTD PMID:29108775 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase multiple interactions
increases activity		 ISO CAT protein inhibits the reaction [[9,10-phenanthrenequinone co-treated with Dithiothreitol] results in decreased activity of and results in increased oxidation of PTPN1 protein]
9,10-phenanthrenequinone results in increased activity of CAT protein		 CTD PMID:32493877 PMID:34391839 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cbr1 carbonyl reductase 1 increases metabolic processing
multiple interactions		 ISO CBR1 protein results in increased metabolism of 9,10-phenanthrenequinone
[CBR1 protein co-treated with NADP] results in increased reduction of and affects the activity of 9,10-phenanthrenequinone; [S-Nitrosoglutathione binds to CBR1 protein] promotes the reaction [CBR1 protein results in increased metabolism of 9,10-phenanthrenequinone]		 CTD PMID:21910479 PMID:23295225 PMID:29108775 NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393 		JBrowse link
G Cbr3 carbonyl reductase 3 increases metabolic processing ISO CBR3 protein results in increased metabolism of 9,10-phenanthrenequinone CTD PMID:19061875 NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases expression ISO 9,10-phenanthrenequinone results in increased expression of CCL11 protein CTD PMID:15669044 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926 		JBrowse link
G Cldn5 claudin 5 multiple interactions
decreases expression		 ISO 1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole inhibits the reaction [9,10-phenanthrenequinone results in decreased expression of CLDN5 protein]; 2,2'-(hydroxynitrosohydrazono)bis-ethanamine promotes the reaction [9,10-phenanthrenequinone results in decreased expression of CLDN5 protein]; 9,10-phenanthrenequinone results in decreased expression of and affects the localization of CLDN5 protein; Acetylcysteine inhibits the reaction [9,10-phenanthrenequinone results in decreased expression of and affects the localization of CLDN5 protein]; Acetylcysteine inhibits the reaction [9,10-phenanthrenequinone results in decreased expression of CLDN5 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [9,10-phenanthrenequinone results in decreased expression of and affects the localization of CLDN5 protein] CTD PMID:34391839 NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992 		JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase multiple interactions
increases metabolic processing		 ISO 9,10-phenanthrenequinone inhibits the reaction [[[DCXR protein co-treated with NAD] results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin]; [CBR2 protein co-treated with NADP] results in increased reduction of and affects the activity of 9,10-phenanthrenequinone; [DCXR protein results in increased metabolism of 9,10-phenanthrenequinone] which results in increased chemical synthesis of Hydroxyl Radical CTD PMID:21910479 PMID:28595002 NCBI chr10:106,006,404...106,008,293 JBrowse link
G Dhrs11 dehydrogenase/reductase 11 increases reduction ISO DHRS11 protein results in increased reduction of 9,10-phenanthrenequinone CTD PMID:30926317 NCBI chr10:69,698,214...69,708,294
Ensembl chr10:69,698,214...69,708,295 		JBrowse link
G Dhrs7 dehydrogenase/reductase 7 increases reduction ISO DHRS7 protein results in increased reduction of 9,10-phenanthrenequinone CTD PMID:24246760 NCBI chr 6:91,332,259...91,347,856
Ensembl chr 6:91,251,323...91,347,892 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
increases phosphorylation		 ISO 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [9,10-phenanthrenequinone results in increased phosphorylation of EGFR protein]; catalase-polyethylene glycol inhibits the reaction [9,10-phenanthrenequinone results in increased phosphorylation of EGFR protein] CTD PMID:32493877 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
decreases expression		 ISO 1,10-phenanthroline inhibits the reaction [9,10-phenanthrenequinone results in decreased expression of HMOX1 protein] CTD PMID:15629867 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Il5 interleukin 5 increases expression ISO 9,10-phenanthrenequinone results in increased expression of IL5 protein CTD PMID:15669044 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions		 ISO 9,10-phenanthrenequinone results in increased phosphorylation of MAPK1 protein
4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [9,10-phenanthrenequinone results in increased phosphorylation of MAPK1 protein]; catalase-polyethylene glycol inhibits the reaction [9,10-phenanthrenequinone results in increased phosphorylation of MAPK1 protein]		 CTD PMID:32493877 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation		 ISO 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [9,10-phenanthrenequinone results in increased phosphorylation of MAPK3 protein]; catalase-polyethylene glycol inhibits the reaction [9,10-phenanthrenequinone results in increased phosphorylation of MAPK3 protein] CTD PMID:32493877 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mmp2 matrix metallopeptidase 2 increases secretion
increases expression		 ISO 9,10-phenanthrenequinone results in increased secretion of MMP2 protein
9,10-phenanthrenequinone results in increased expression of MMP2 mRNA		 CTD PMID:24813866 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 affects localization ISO 9,10-phenanthrenequinone affects the localization of NFE2L2 protein CTD PMID:29108775 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nos2 nitric oxide synthase 2 increases expression ISO 9,10-phenanthrenequinone results in increased expression of NOS2 protein CTD PMID:34391839 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nos3 nitric oxide synthase 3 decreases expression ISO 9,10-phenanthrenequinone results in decreased expression of NOS3 protein CTD PMID:34391839 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases expression
increases metabolic processing
increases response to substance		 ISO [NQO1 protein co-treated with NADP] results in increased reduction of and affects the activity of 9,10-phenanthrenequinone; Acetylcysteine inhibits the reaction [NQO1 protein results in increased susceptibility to 9,10-phenanthrenequinone]; NQO1 protein promotes the reaction [Acetylcysteine results in decreased susceptibility to 9,10-phenanthrenequinone]
9,10-phenanthrenequinone results in increased expression of NQO1 protein
NQO1 protein results in increased metabolism of 9,10-phenanthrenequinone		 CTD PMID:21910479 PMID:22925602 PMID:29108775 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO 9,10-phenanthrenequinone results in increased expression of PMAIP1 protein CTD PMID:29108775 NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Prdx1 peroxiredoxin 1 multiple interactions ISO 9,10-phenanthrenequinone promotes the reaction [PRDX1 protein binds to PRDX1 protein] CTD PMID:32493877 NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 multiple interactions ISO [9,10-phenanthrenequinone co-treated with Dithiothreitol] results in decreased activity of and results in increased oxidation of PTPN1 protein; CAT protein inhibits the reaction [[9,10-phenanthrenequinone co-treated with Dithiothreitol] results in decreased activity of and results in increased oxidation of PTPN1 protein] CTD PMID:32493877 NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
decreases expression		 ISO 1,10-phenanthroline inhibits the reaction [9,10-phenanthrenequinone results in decreased expression of SOD1 protein] CTD PMID:15629867 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Top2a DNA topoisomerase II alpha multiple interactions ISO 9,10-phenanthrenequinone binds to and results in decreased activity of TOP2A protein CTD PMID:22218491 NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
G Tp53 tumor protein p53 affects localization ISO 9,10-phenanthrenequinone affects the localization of TP53 protein CTD PMID:29108775 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
9-phenanthrol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ano1 anoctamin 1 multiple interactions ISO 9-phenanthrol inhibits the reaction [Calcium results in increased activity of ANO1 protein] CTD PMID:25573456 NCBI chr 1:199,751,439...199,900,099
Ensembl chr 1:199,751,439...199,900,069 		JBrowse link
G Ar androgen receptor multiple interactions EXP
ISO		 9-phenanthrol inhibits the reaction [Metribolone binds to AR protein]
9-phenanthrol inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]		 CTD PMID:3695475 PMID:33049310 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G C3 complement C3 increases expression ISO 9-phenanthrol results in increased expression of C3 mRNA CTD PMID:22989670 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases abundance
multiple interactions		 ISO CYP1A1 protein results in increased abundance of 9-phenanthrol
[CYP1A1 protein results in increased oxidation of phenanthrene] which results in increased abundance of 9-phenanthrol		 CTD PMID:27137136 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases abundance		 ISO [CYP1A2 protein results in increased oxidation of phenanthrene] which results in increased abundance of 9-phenanthrol
CYP1A2 protein results in increased abundance of 9-phenanthrol		 CTD PMID:27137136 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases abundance
multiple interactions		 ISO CYP1B1 protein results in increased abundance of 9-phenanthrol
[CYP1B1 protein results in increased oxidation of phenanthrene] which results in increased abundance of 9-phenanthrol		 CTD PMID:27137136 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 multiple interactions
increases abundance		 ISO [CYP2A13 protein results in increased oxidation of phenanthrene] which results in increased abundance of 9-phenanthrol
CYP2A13 protein results in increased abundance of 9-phenanthrol		 CTD PMID:27137136 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO 9-phenanthrol binds to and results in decreased activity of ESR1 protein CTD PMID:33049310 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 affects binding
multiple interactions		 ISO ESR2 protein binds to 9-phenanthrol
9-phenanthrol inhibits the reaction [ESR2 protein binds to Estradiol]		 CTD PMID:22989670 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions ISO 9-phenanthrol inhibits the reaction [Lipopolysaccharides results in increased expression of FTH1 mRNA] CTD PMID:27246103 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424 		JBrowse link
G Gcg glucagon multiple interactions EXP 9-phenanthrol inhibits the reaction [[GCG protein co-treated with Glucose] results in increased secretion of INS1 protein] CTD PMID:29098165 NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO 9-phenanthrol inhibits the reaction [Hydrogen Peroxide results in increased secretion of ICAM1 protein] CTD PMID:28214884 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Ins1 insulin 1 multiple interactions
increases secretion		 EXP 9-phenanthrol inhibits the reaction [[GCG protein co-treated with Glucose] results in increased secretion of INS1 protein]; 9-phenanthrol inhibits the reaction [Glucose results in increased secretion of INS1 protein]
9-phenanthrol results in increased secretion of INS1 protein		 CTD PMID:29098165 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536 		JBrowse link
G Jag1 jagged canonical Notch ligand 1 decreases expression ISO 9-phenanthrol results in decreased expression of JAG1 mRNA CTD PMID:22989670 NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 multiple interactions ISO 9-phenanthrol inhibits the reaction [Lipopolysaccharides affects the localization of NFATC1 protein] CTD PMID:27246103 NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO 9-phenanthrol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; 9-phenanthrol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:27246103 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO 9-phenanthrol binds to and affects the activity of NR1I2 protein
9-phenanthrol binds to and results in increased activity of NR1I2 protein		 CTD PMID:33049310 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nrip1 nuclear receptor interacting protein 1 increases expression ISO 9-phenanthrol results in increased expression of NRIP1 mRNA CTD PMID:22989670 NCBI chr11:14,895,843...14,979,490
Ensembl chr11:14,895,553...14,981,761 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO 9-phenanthrol binds to and affects the activity of PPARG protein
9-phenanthrol binds to and results in increased activity of PPARG protein		 CTD PMID:33049310 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 decreases activity ISO 9-phenanthrol results in decreased activity of SCN5A protein mutant form CTD PMID:30153324 NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769 		JBrowse link
G Sele selectin E multiple interactions ISO 9-phenanthrol inhibits the reaction [Hydrogen Peroxide results in increased secretion of SELE protein] CTD PMID:28214884 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741 		JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO 9-phenanthrol binds to and results in increased activity of THRA protein CTD PMID:33049310 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936 		JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO 9-phenanthrol binds to and results in increased activity of THRB protein CTD PMID:33049310 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916 		JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 multiple interactions
decreases activity		 ISO 9-phenanthrol inhibits the reaction [Arsenic Trioxide results in increased expression of TRPM4 protein]; 9-phenanthrol inhibits the reaction [Glutamic Acid results in increased activity of TRPM4 protein]; 9-phenanthrol inhibits the reaction [Hydrogen Peroxide results in increased expression of TRPM4 protein]
9-phenanthrol results in decreased activity of TRPM4 protein		 CTD PMID:25047048 PMID:28214884 PMID:31054354 PMID:34335274 NCBI chr 1:95,781,805...95,812,095
Ensembl chr 1:95,782,000...95,812,532 		JBrowse link
G Trpm5 transient receptor potential cation channel, subfamily M, member 5 decreases activity ISO 9-phenanthrol results in decreased activity of TRPM5 protein CTD PMID:18297105 NCBI chr 1:198,254,956...198,277,824
Ensembl chr 1:198,255,723...198,277,654 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO 9-phenanthrol inhibits the reaction [Hydrogen Peroxide results in increased secretion of VCAM1 protein] CTD PMID:28214884 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958 		JBrowse link
Altertoxin I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Top2a DNA topoisomerase II alpha decreases activity ISO altertoxin I results in decreased activity of TOP2A protein CTD PMID:27682608 NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
Benz[j]aceanthrylene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kras KRAS proto-oncogene, GTPase increases mutagenesis ISO benz(j)aceanthrylene results in increased mutagenesis of KRAS gene CTD PMID:9659573 NCBI chr 4:178,185,418...178,218,484 JBrowse link
Dibenz[a,j]anthracene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions
increases activity		 EXP dibenzo(aj)anthracene binds to and results in increased activity of AHR protein; dibenzo(aj)anthracene inhibits the reaction [Benzo(a)pyrene binds to AHR protein]
dibenzo(aj)anthracene results in increased activity of AHR protein		 CTD PMID:11525907 PMID:28104439 PMID:29471110 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP dibenzo(aj)anthracene results in increased expression of CYP1A1 protein CTD PMID:28104439 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
Halofantrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO halofantrine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
methylnaltrexone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Oprm1 opioid receptor, mu 1 affects binding ISO methylnaltrexone binds to OPRM1 protein CTD PMID:17340127 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
Norbuprenorphine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO norbuprenorphine results in decreased activity of CYP2D6 protein CTD PMID:12756210 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 affects chemical synthesis
decreases activity		 ISO CYP3A4 protein affects the chemical synthesis of norbuprenorphine
norbuprenorphine results in decreased activity of CYP3A4 protein		 CTD PMID:12756210 PMID:15966752 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
Noroxycodone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO telithromycin inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of noroxycodone] CTD PMID:19755414 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
OSU-03012 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
decreases response to substance		 ISO OSU 03012 results in decreased phosphorylation of AKT1 protein
AKT1 protein modified form results in decreased susceptibility to OSU 03012		 CTD PMID:15205346 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 multiple interactions
decreases response to substance		 ISO OSU 03012 binds to and results in decreased activity of PDPK1 protein
PDPK1 protein modified form results in decreased susceptibility to OSU 03012		 CTD PMID:15205346 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623 		JBrowse link
phenanthrene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp2 acid phosphatase 2, lysosomal multiple interactions
affects expression		 ISO [naphthalene co-treated with anthracene co-treated with phenanthrene co-treated with pyrene] affects the expression of ACP2 protein
phenanthrene affects the expression of ACP2 protein		 CTD PMID:28803881 NCBI chr 3:77,175,022...77,185,180
Ensembl chr 3:77,175,895...77,185,680 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
affects binding
increases activity		 EXP
ISO		 phenanthrene binds to and results in increased activity of AHR protein
phenanthrene binds to AHR protein
[acenaphthene co-treated with anthracene co-treated with 1,12-benzoperylene co-treated with 1,2,5,6-dibenzanthracene co-treated with fluorene co-treated with naphthalene co-treated with phenanthrene] results in increased activity of AHR protein; [naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in decreased expression of AHR protein; [phenanthrene co-treated with naphthalene] inhibits the reaction [Benzo(a)pyrene results in increased activity of AHR protein]; [pyrene co-treated with phenanthrene] inhibits the reaction [Benzo(a)pyrene results in increased activity of AHR protein]; AHR protein affects the reaction [[naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in decreased expression of AR protein]; AHR protein affects the reaction [[naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in increased expression of ESR1 protein]; AHRR protein affects the reaction [[naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in decreased expression of AHR protein]; phenanthrene inhibits the reaction [Benzo(a)pyrene results in increased activity of AHR protein]
phenanthrene results in increased activity of AHR protein		 CTD PMID:3024361 PMID:12850102 PMID:17665671 PMID:28710019 PMID:29502740 More... NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Ahrr aryl-hydrocarbon receptor repressor multiple interactions ISO [naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in decreased expression of AHRR protein; AHRR protein affects the reaction [[naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in decreased expression of AHR protein]; AHRR protein affects the reaction [[naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in decreased expression of CYP1A1 protein] CTD PMID:28710019 PMID:30980910 NCBI chr 1:28,993,634...29,088,673
Ensembl chr 1:28,993,634...29,088,673 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 decreases expression ISO phenanthrene results in decreased expression of AKR1C1 mRNA CTD PMID:38568856 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation ISO phenanthrene results in increased phosphorylation of AKT1 protein CTD PMID:34453960 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 increases expression
decreases expression		 ISO phenanthrene results in increased expression of ALDH3A1 mRNA
phenanthrene results in decreased expression of ALDH3A1 mRNA		 CTD PMID:32890658 PMID:38568856 NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681 		JBrowse link
G Alyref Aly/REF export factor decreases expression ISO phenanthrene results in decreased expression of ALYREF mRNA CTD PMID:38568856 NCBI chr10:105,871,424...105,875,076
Ensembl chr10:105,871,306...105,875,069 		JBrowse link
G Ankrd52 ankyrin repeat domain 52 decreases expression ISO phenanthrene results in decreased expression of ANKRD52 mRNA CTD PMID:38568856 NCBI chr 7:806,829...820,481
Ensembl chr 7:806,767...820,481 		JBrowse link
G Ar androgen receptor affects binding
multiple interactions		 EXP
ISO		 phenanthrene analog binds to AR protein
[naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in decreased expression of AR protein; AHR protein affects the reaction [[naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in decreased expression of AR protein]; phenanthrene inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; phenanthrene inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]
phenanthrene analog inhibits the reaction [Androgens binds to AR protein]; phenanthrene analog inhibits the reaction [Metribolone binds to AR protein]; phenanthrene inhibits the reaction [Metribolone binds to AR protein]		 CTD PMID:3695475 PMID:6323860 PMID:26022396 PMID:30980910 PMID:33049310 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO [naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] affects the expression of ARNT protein; [naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in decreased expression of ARNT mRNA; [naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in increased expression of ARNT mRNA CTD PMID:28710019 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580 		JBrowse link
G Atf4 activating transcription factor 4 decreases expression ISO phenanthrene results in decreased expression of ATF4 mRNA CTD PMID:38568856 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Aven apoptosis and caspase activation inhibitor decreases expression ISO phenanthrene results in decreased expression of AVEN mRNA CTD PMID:38568856 NCBI chr 3:99,299,009...99,431,635
Ensembl chr 3:99,298,930...99,431,634 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
affects expression		 ISO [naphthalene co-treated with anthracene co-treated with phenanthrene co-treated with pyrene] affects the expression of BAX protein
phenanthrene affects the expression of BAX protein		 CTD PMID:28803881 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Becn1 beclin 1 multiple interactions
decreases expression		 ISO Sirolimus inhibits the reaction [phenanthrene results in decreased expression of BECN1 mRNA] CTD PMID:34453960 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression		 ISO [naphthalene co-treated with anthracene co-treated with phenanthrene co-treated with pyrene] results in increased expression of CASP3 protein
phenanthrene results in increased expression of CASP3 protein		 CTD PMID:28803881 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cat catalase increases expression
multiple interactions
increases activity		 ISO phenanthrene results in increased expression of CAT protein
[phenanthrene co-treated with fluorene] results in increased activity of CAT protein
phenanthrene results in increased activity of CAT protein		 CTD PMID:20238386 PMID:32856796 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccna2 cyclin A2 decreases expression
multiple interactions		 ISO phenanthrene results in decreased expression of CCNA2 protein
[naphthalene co-treated with anthracene co-treated with phenanthrene co-treated with pyrene] results in decreased expression of CCNA2 protein		 CTD PMID:28803881 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions
increases expression		 ISO [naphthalene co-treated with anthracene co-treated with phenanthrene co-treated with pyrene] results in increased expression of CCND1 protein
phenanthrene results in increased expression of CCND1 protein		 CTD PMID:28803881 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions
increases expression		 ISO [naphthalene co-treated with anthracene co-treated with phenanthrene co-treated with pyrene] results in increased expression of CDK2 protein
phenanthrene results in increased expression of CDK2 protein		 CTD PMID:28803881 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C decreases expression ISO phenanthrene results in decreased expression of CDKN1C mRNA CTD PMID:38568856 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048 		JBrowse link
G Comt catechol-O-methyltransferase multiple interactions ISO [naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] affects the expression of COMT mRNA; [naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in increased expression of and affects the activity of COMT protein CTD PMID:28710019 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A decreases expression ISO phenanthrene results in decreased expression of CPT1A mRNA CTD PMID:38568856 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Cul4b cullin 4B decreases expression ISO phenanthrene results in decreased expression of CUL4B mRNA CTD PMID:38568856 NCBI chr  X:117,287,481...117,326,688
Ensembl chr  X:117,287,484...117,326,688 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions
increases expression		 ISO [naphthalene co-treated with anthracene co-treated with phenanthrene co-treated with pyrene] affects the expression of CYP19A1 protein
phenanthrene results in increased expression of CYP19A1 protein		 CTD PMID:28803881 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
increases oxidation
increases metabolic processing
increases activity		 ISO
EXP		 [CYP1A1 protein results in increased oxidation of phenanthrene] which results in increased abundance of 9-phenanthrol; [naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] affects the expression of CYP1A1 mRNA; [naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] affects the expression of CYP1A1 protein; [naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in decreased expression of CYP1A1 protein; [phenanthrene co-treated with pyrene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with dibenzo(a,l)pyrene co-treated with benzo(b)fluoranthene] results in increased expression of CYP1A1 mRNA; AHRR protein affects the reaction [[naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in decreased expression of CYP1A1 protein]; CYP1A1 protein results in increased metabolism of and results in increased activity of phenanthrene; GSTM1 gene polymorphism promotes the reaction [CYP1A1 gene polymorphism results in increased metabolism of phenanthrene]
phenanthrene results in increased expression of CYP1A1 mRNA
phenanthrene results in increased expression of CYP1A1 mRNA; phenanthrene results in increased expression of CYP1A1 protein
phenanthrene results in increased activity of CYP1A1 protein		 CTD PMID:15566942 PMID:16906435 PMID:17035385 PMID:19766613 PMID:27137136 More... NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases activity
increases expression
increases oxidation
multiple interactions		 ISO phenanthrene results in increased activity of CYP1A2 protein
phenanthrene results in increased expression of CYP1A2 mRNA; phenanthrene results in increased expression of CYP1A2 protein
CYP1A2 protein results in increased oxidation of phenanthrene
[acenaphthylene co-treated with acenaphthene co-treated with dibenzofuran co-treated with fluorene co-treated with phenanthrene co-treated with anthracene] results in increased expression of CYP1A2 mRNA; CYP1A2 protein results in increased metabolism of and results in increased activity of phenanthrene
[CYP1A2 protein results in increased oxidation of phenanthrene] which results in increased abundance of 9-phenanthrol; CYP1A2 protein results in increased metabolism of and results in increased activity of phenanthrene		 CTD PMID:7750161 PMID:8001243 PMID:19766613 PMID:27137136 PMID:31181217 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions
increases expression
increases oxidation
decreases metabolic processing		 ISO [CYP1B1 protein results in increased oxidation of phenanthrene] which results in increased abundance of 9-phenanthrol; [phenanthrene co-treated with pyrene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with dibenzo(a,l)pyrene co-treated with benzo(b)fluoranthene] results in increased expression of CYP1B1 mRNA; CYP1B1 protein results in increased metabolism of and results in increased activity of phenanthrene; phenanthrene binds to and results in decreased activity of CYP1B1 protein
phenanthrene results in increased expression of CYP1B1 mRNA
CYP1B1 gene polymorphism results in decreased metabolism of phenanthrene		 CTD PMID:15566942 PMID:17035385 PMID:19563207 PMID:19766613 PMID:27137136 More... NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 increases oxidation
affects binding
multiple interactions		 ISO CYP2A13 protein results in increased oxidation of phenanthrene
phenanthrene binds to CYP2A13 protein
[CYP2A13 protein results in increased oxidation of phenanthrene] which results in increased abundance of 9-phenanthrol		 CTD PMID:27137136 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression
multiple interactions		 ISO phenanthrene results in increased expression of CYP2B6 mRNA
phenanthrene results in increased expression of CYP2B10 mRNA; phenanthrene results in increased expression of CYP2B10 protein
NR1I3 gene mutant form inhibits the reaction [phenanthrene results in increased expression of CYP2B10 mRNA]; NR1I3 gene mutant form inhibits the reaction [phenanthrene results in increased expression of CYP2B10 protein]		 CTD PMID:31181217 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases metabolic processing ISO CYP2D6 protein results in increased metabolism of phenanthrene CTD PMID:9429232 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO CYP2E1 protein results in increased metabolism of and results in increased activity of phenanthrene CTD PMID:19766613 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 decreases expression ISO phenanthrene results in decreased expression of EEF1A1 mRNA CTD PMID:38568856 NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839 		JBrowse link
G Egr1 early growth response 1 increases expression ISO phenanthrene results in increased expression of EGR1 protein CTD PMID:15342960 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Eif4e eukaryotic translation initiation factor 4E increases expression ISO phenanthrene results in increased expression of EIF4E mRNA CTD PMID:34453960 NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO [naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in increased expression of ESR1 protein; AHR protein affects the reaction [[naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in increased expression of ESR1 protein]; phenanthrene analog binds to and results in decreased activity of ESR1 protein; phenanthrene binds to and results in increased activity of ESR1 protein CTD PMID:12672240 PMID:30980910 PMID:33049310 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 affects binding ISO phenanthrene analog binds to ESR2 protein CTD PMID:12672240 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Foxp3 forkhead box P3 decreases expression EXP phenanthrene results in decreased expression of FOXP3 mRNA; phenanthrene results in decreased expression of FOXP3 protein CTD PMID:31456356 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Foxp4 forkhead box P4 decreases expression ISO phenanthrene results in decreased expression of FOXP4 mRNA CTD PMID:38568856 NCBI chr 9:13,058,506...13,115,406
Ensembl chr 9:13,058,476...13,114,879 		JBrowse link
G Gjb1 gap junction protein, beta 1 decreases expression EXP phenanthrene results in decreased expression of GJB1 protein CTD PMID:25268939 NCBI chr  X:66,501,848...66,509,783
Ensembl chr  X:66,501,820...66,509,925 		JBrowse link
G Gnas GNAS complex locus increases expression ISO phenanthrene results in increased expression of GNAS mRNA CTD PMID:38568856 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha decreases expression ISO phenanthrene results in decreased expression of GSK3A mRNA CTD PMID:38568856 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802 		JBrowse link
G Gsr glutathione-disulfide reductase increases expression ISO phenanthrene results in increased expression of GSR protein CTD PMID:20238386 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Gsta1 glutathione S-transferase alpha 1 increases expression ISO phenanthrene results in increased expression of GSTA1 mRNA CTD PMID:32890658 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions
affects metabolic processing		 ISO GSTM1 gene polymorphism promotes the reaction [CYP1A1 gene polymorphism results in increased metabolism of phenanthrene]
GSTM1 protein affects the metabolism of phenanthrene		 CTD PMID:17035385 PMID:22674470 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstm5 glutathione S-transferase, mu 5 multiple interactions
increases expression		 ISO NR1I3 gene mutant form inhibits the reaction [phenanthrene results in increased expression of GSTM3 mRNA] CTD PMID:31181217 NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553 		JBrowse link
G Hmga2 high mobility group AT-hook 2 decreases expression ISO phenanthrene results in decreased expression of HMGA2 mRNA CTD PMID:38568856 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784 		JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO phenanthrene results in increased expression of ICAM1 protein CTD PMID:22313677 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Ier3 immediate early response 3 increases expression
decreases expression		 ISO phenanthrene results in increased expression of IER3 mRNA
phenanthrene results in decreased expression of IER3 mRNA		 CTD PMID:22579512 PMID:38568856 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583 		JBrowse link
G Ighe immunoglobulin heavy constant epsilon affects expression
increases expression		 ISO phenanthrene affects the expression of IGHE mRNA alternative form
phenanthrene results in increased expression of IGHE mRNA; phenanthrene results in increased expression of IGHE protein		 CTD PMID:9070347
G Il10 interleukin 10 decreases expression EXP phenanthrene results in decreased expression of IL10 mRNA; phenanthrene results in decreased expression of IL10 protein CTD PMID:31456356 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions		 EXP
ISO		 phenanthrene results in increased expression of IL6 mRNA; phenanthrene results in increased expression of IL6 protein
[fluorene co-treated with phenanthrene] results in increased expression of IL6 mRNA; [fluorene co-treated with phenanthrene] results in increased expression of IL6 protein		 CTD PMID:31456356 PMID:32856796 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Krt16 keratin 16 decreases expression ISO phenanthrene results in decreased expression of KRT16 mRNA CTD PMID:38568856 NCBI chr10:85,168,357...85,171,816
Ensembl chr10:85,066,802...85,171,799 		JBrowse link
G Krt5 keratin 5 decreases expression ISO phenanthrene results in decreased expression of KRT5 mRNA CTD PMID:38568856 NCBI chr 7:132,846,132...132,851,861
Ensembl chr 7:132,846,136...132,851,850 		JBrowse link
G Lama3 laminin subunit alpha 3 increases expression ISO phenanthrene results in increased expression of LAMA3 mRNA CTD PMID:38568856 NCBI chr18:3,523,168...3,751,722
Ensembl chr18:3,523,133...3,751,353 		JBrowse link
G Lama5 laminin subunit alpha 5 decreases expression ISO phenanthrene results in decreased expression of LAMA5 mRNA CTD PMID:38568856 NCBI chr 3:167,270,296...167,318,370
Ensembl chr 3:167,270,296...167,318,451 		JBrowse link
G Lgals1 galectin 1 increases expression ISO phenanthrene results in increased expression of LGALS1 mRNA CTD PMID:22579512 NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345 		JBrowse link
G Mcam melanoma cell adhesion molecule decreases expression ISO phenanthrene results in decreased expression of MCAM mRNA CTD PMID:38568856 NCBI chr 8:44,479,391...44,487,575
Ensembl chr 8:44,479,376...44,487,571 		JBrowse link
G Mllt1 MLLT1, super elongation complex subunit decreases expression ISO phenanthrene results in decreased expression of MLLT1 mRNA CTD PMID:38568856 NCBI chr 9:1,731,077...1,775,985
Ensembl chr 9:1,731,080...1,775,970 		JBrowse link
G Mt-nd3 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3 decreases expression ISO phenanthrene results in decreased expression of ND3 mRNA CTD PMID:38568856 NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
Ensembl chr MT:9,451...9,798 		JBrowse link
G Mt2A metallothionein 2A decreases expression ISO phenanthrene results in decreased expression of MT2A mRNA CTD PMID:38568856 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Nacc1 nucleus accumbens associated 1 decreases expression ISO phenanthrene results in decreased expression of NACC1 mRNA CTD PMID:38568856 NCBI chr19:23,468,688...23,486,528
Ensembl chr19:23,468,419...23,486,528 		JBrowse link
G Ndc80 NDC80 kinetochore complex component decreases expression ISO phenanthrene results in decreased expression of NDC80 mRNA CTD PMID:22579512 NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924 		JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 multiple interactions ISO [naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in increased expression of NFKB2 protein CTD PMID:30980910 NCBI chr 1:245,164,586...245,173,225
Ensembl chr 1:245,165,950...245,173,213 		JBrowse link
G Niban2 niban apoptosis regulator 2 decreases expression ISO phenanthrene results in decreased expression of NIBAN2 mRNA CTD PMID:38568856 NCBI chr 3:16,174,674...16,224,293
Ensembl chr 3:16,174,659...16,224,293 		JBrowse link
G Nlgn1 neuroligin 1 decreases expression ISO phenanthrene results in decreased expression of NLGN1 mRNA CTD PMID:34453960 NCBI chr 2:108,256,236...109,181,530
Ensembl chr 2:108,257,824...109,002,464 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases activity
increases expression		 EXP
ISO		 phenanthrene results in increased activity of NQO1 protein
phenanthrene results in increased expression of NQO1 mRNA		 CTD PMID:16906435 PMID:31181217 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO phenanthrene binds to and results in increased activity of NR1I2 protein CTD PMID:33049310 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity
multiple interactions		 ISO phenanthrene results in increased activity of NR1I3 protein
NR1I3 gene mutant form inhibits the reaction [phenanthrene results in increased expression of CYP2B10 mRNA]; NR1I3 gene mutant form inhibits the reaction [phenanthrene results in increased expression of CYP2B10 protein]; NR1I3 gene mutant form inhibits the reaction [phenanthrene results in increased expression of CYP3A11 mRNA]; NR1I3 gene mutant form inhibits the reaction [phenanthrene results in increased expression of GSTM3 mRNA]; NR1I3 gene mutant form inhibits the reaction [phenanthrene results in increased expression of SULT2A1 mRNA]; NR1I3 gene mutant form inhibits the reaction [phenanthrene results in increased expression of UGT1A1 mRNA]		 CTD PMID:28927721 PMID:31181217 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Pah phenylalanine hydroxylase decreases expression ISO phenanthrene results in decreased expression of PAH mRNA CTD PMID:22579512 NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:21,933,179...21,998,130 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO phenanthrene results in increased cleavage of PARP1 protein CTD PMID:21132278 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pgr progesterone receptor multiple interactions ISO phenanthrene inhibits the reaction [16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione results in increased activity of PGR protein] CTD PMID:26022396 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
G Pou5f1 POU class 5 homeobox 1 multiple interactions
decreases expression		 ISO phenanthrene affects the reaction [Tretinoin results in decreased expression of POU5F1 protein]
phenanthrene results in decreased expression of POU5F1 protein		 CTD PMID:21111795 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891 		JBrowse link
G Rhoc ras homolog family member C increases expression ISO phenanthrene results in increased expression of RHOC mRNA CTD PMID:22579512 NCBI chr 2:192,287,065...192,293,292
Ensembl chr 2:192,287,130...192,295,306 		JBrowse link
G Rnf44 ring finger protein 44 decreases expression ISO phenanthrene results in decreased expression of RNF44 mRNA CTD PMID:38568856 NCBI chr17:9,919,982...9,934,376
Ensembl chr17:9,919,993...9,932,193 		JBrowse link
G Rpl24 ribosomal protein L24 decreases expression ISO phenanthrene results in decreased expression of RPL24 mRNA CTD PMID:38568856 NCBI chr11:44,653,937...44,659,346
Ensembl chr11:44,653,937...44,659,370 		JBrowse link
G Rpl27a ribosomal protein L27A decreases expression ISO phenanthrene results in decreased expression of RPL27A mRNA CTD PMID:38568856 NCBI chr 1:163,539,732...163,542,771 JBrowse link
G Rpl28 ribosomal protein L28 decreases expression ISO phenanthrene results in decreased expression of RPL28 mRNA CTD PMID:38568856 NCBI chr 1:69,052,148...69,054,735
Ensembl chr 1:69,053,203...69,055,032 		JBrowse link
G Rpl30 ribosomal protein L30 decreases expression ISO phenanthrene results in decreased expression of RPL30 mRNA CTD PMID:38568856 NCBI chr 7:65,648,266...65,651,401
Ensembl chr 7:65,645,991...65,651,363
Ensembl chr10:65,645,991...65,651,363
Ensembl chr 1:65,645,991...65,651,363 		JBrowse link
G Rpl37a ribosomal protein L37A decreases expression ISO phenanthrene results in decreased expression of RPL37A mRNA CTD PMID:38568856 NCBI chr 9:74,298,843...74,300,926 JBrowse link
G Rpl39 ribosomal protein L39 decreases expression ISO phenanthrene results in decreased expression of RPL39 mRNA CTD PMID:38568856 NCBI chr  X:116,327,216...116,330,211
Ensembl chr18:6,326,330...6,326,692
Ensembl chr  X:6,326,330...6,326,692
Ensembl chr  X:6,326,330...6,326,692
Ensembl chr15:6,326,330...6,326,692
Ensembl chr20:6,326,330...6,326,692
Ensembl chr 7:6,326,330...6,326,692 		JBrowse link
G Rpl5 ribosomal protein L5 decreases expression ISO phenanthrene results in decreased expression of RPL5 mRNA CTD PMID:38568856 NCBI chr14:1,843,856...1,850,301
Ensembl chr14:1,843,770...1,850,290 		JBrowse link
G Rpl7a ribosomal protein L7A decreases expression ISO phenanthrene results in decreased expression of RPL7A mRNA CTD PMID:38568856 NCBI chr 3:10,239,026...10,241,703
Ensembl chr 3:10,239,001...10,241,716
Ensembl chr18:10,239,001...10,241,716 		JBrowse link
G Rplp2 ribosomal protein lateral stalk subunit P2 decreases expression ISO phenanthrene results in decreased expression of RPLP2 mRNA CTD PMID:38568856 NCBI chr 1:196,546,086...196,548,636
Ensembl chr 1:196,546,352...196,548,645 		JBrowse link
G Rps12 ribosomal protein S12 decreases expression ISO phenanthrene results in decreased expression of RPS12 mRNA CTD PMID:38568856 NCBI chr 1:21,680,854...21,683,010
Ensembl chr 1:21,680,852...21,683,014 		JBrowse link
G Rps15a ribosomal protein S15a decreases expression ISO phenanthrene results in decreased expression of RPS15A mRNA CTD PMID:38568856 NCBI chr 1:172,420,151...172,427,021
Ensembl chr 1:172,419,761...172,426,995 		JBrowse link
G Rps21-ps1 ribosomal protein S21, pseudogene 1 decreases expression ISO phenanthrene results in decreased expression of RPS21 mRNA CTD PMID:38568856 NCBI chr 5:153,387,133...153,387,476
Ensembl chr 5:153,387,176...153,387,427 		JBrowse link
G Rps29 ribosomal protein S29 decreases expression ISO phenanthrene results in decreased expression of RPS29 mRNA CTD PMID:38568856 NCBI chr 6:87,635,229...87,636,627
Ensembl chr 6:87,635,230...87,636,636
Ensembl chr13:87,635,230...87,636,636 		JBrowse link
G Rpsa ribosomal protein SA decreases expression ISO phenanthrene results in decreased expression of RPSA mRNA CTD PMID:38568856 NCBI chr 8:119,851,225...119,855,103
Ensembl chr 8:119,851,225...119,855,247 		JBrowse link
G RT1-CE16 RT1 class I, locus CE16 decreases expression ISO phenanthrene results in decreased expression of HLA-A mRNA CTD PMID:38568856 NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563 		JBrowse link
G S100a13 S100 calcium binding protein A13 decreases expression ISO phenanthrene results in decreased expression of S100A13 mRNA CTD PMID:38568856 NCBI chr 2:175,999,439...176,005,933 JBrowse link
G S100a8 S100 calcium binding protein A8 decreases expression ISO phenanthrene results in decreased expression of S100A8 mRNA CTD PMID:38568856 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643 		JBrowse link
G Sf3a2 splicing factor 3A subunit 2 decreases expression ISO phenanthrene results in decreased expression of SF3A2 mRNA CTD PMID:38568856 NCBI chr 7:8,909,507...8,916,104
Ensembl chr 7:8,909,507...8,915,530 		JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 multiple interactions
decreases expression		 ISO Sirolimus inhibits the reaction [phenanthrene results in decreased expression of SHANK3 mRNA] CTD PMID:34453960 NCBI chr 7:120,568,707...120,630,796
Ensembl chr 7:120,570,402...120,630,374 		JBrowse link
G Sod2 superoxide dismutase 2 increases expression ISO phenanthrene results in increased expression of SOD2 protein CTD PMID:20238386 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 increases expression
multiple interactions		 ISO phenanthrene results in increased expression of SULT2A1 mRNA
NR1I3 gene mutant form inhibits the reaction [phenanthrene results in increased expression of SULT2A1 mRNA]		 CTD PMID:31181217 NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression EXP phenanthrene results in decreased expression of TGFB1 mRNA; phenanthrene results in decreased expression of TGFB1 protein CTD PMID:31456356 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO phenanthrene results in increased expression of TIMP1 mRNA CTD PMID:22579512 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 decreases expression ISO phenanthrene results in decreased expression of TIMP2 mRNA CTD PMID:38568856 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611 		JBrowse link
G Tmt1a thiol methyltransferase 1A decreases expression ISO phenanthrene results in decreased expression of METTL7A mRNA CTD PMID:38568856 NCBI chr 7:131,452,099...131,460,154
Ensembl chr 7:131,451,641...131,460,154 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression		 ISO
EXP		 [fluorene co-treated with phenanthrene] results in increased expression of TNF mRNA; [fluorene co-treated with phenanthrene] results in increased expression of TNF protein; TNF protein promotes the reaction [phenanthrene results in increased expression of CXCL8 mRNA]
phenanthrene results in increased expression of TNF protein
phenanthrene results in increased expression of TNF mRNA; phenanthrene results in increased expression of TNF protein		 CTD PMID:18434080 PMID:31456356 PMID:32856796 PMID:34453960 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tpt1 tumor protein, translationally-controlled 1 decreases expression ISO phenanthrene results in decreased expression of TPT1 mRNA CTD PMID:38568856 NCBI chr15:51,156,728...51,159,629
Ensembl chr15:51,146,154...51,159,625 		JBrowse link
G Tuba1c tubulin, alpha 1C decreases expression ISO phenanthrene results in decreased expression of TUBA1C mRNA CTD PMID:38568856 NCBI chr 7:130,192,050...130,199,655
Ensembl chr 7:130,192,016...130,199,647
Ensembl chr  X:130,192,016...130,199,647 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression
multiple interactions		 ISO phenanthrene results in increased expression of UGT1A1 mRNA
NR1I3 gene mutant form inhibits the reaction [phenanthrene results in increased expression of UGT1A1 mRNA]		 CTD PMID:31181217 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 multiple interactions ISO [phenanthrene co-treated with pyrene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with dibenzo(a,l)pyrene co-treated with benzo(b)fluoranthene] results in increased expression of UGT1A6 mRNA CTD PMID:15566942 NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Vegfb vascular endothelial growth factor B decreases expression ISO phenanthrene results in decreased expression of VEGFB mRNA CTD PMID:38568856 NCBI chr 1:204,172,297...204,178,046
Ensembl chr 1:204,172,225...204,177,944 		JBrowse link
G Zbed6 zinc finger, BED-type containing 6 decreases expression ISO phenanthrene results in decreased expression of ZBED6 mRNA CTD PMID:38568856 NCBI chr13:45,107,253...45,113,524
Ensembl chr13:45,071,718...45,114,009 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    role 19850
      biological role 19848
        xenobiotic 18728
          phenanthrenes 303
            (+)-Eurotone A 0
            (+)-murayaquinone B 0
            (+)-variecolortin B 0
            (+/-)-variecolortin B 0
            (+/-)-variecolortin C 0
            (-)-Eurotone A 0
            (-)-murayaquinone B 0
            (-)-variecolortin C 0
            (1R,4R,4aR,4bS,7R)-7-ethenyl-4,4b,10-trihydroxy-1,4a,7-trimethyl-9-oxo-3,4,5,6-tetrahydro-2H-phenanthrene-1-carboxylic acid 0
            (3R)-3,7,8-trihydroxy-3-methyl-4,5-dihydro-2H-benzo[a]anthracene-1,6-dione 0
            (4R,4aS,12bS)-3-(cyclobutylmethyl)-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,7,9-triol 0
            (4R,4aS,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one 0
            (4R,4aS,7S,12bS)-3-(cyclobutylmethyl)-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,7,9-triol 0
            (4R,4aS,7aR)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one 0
            (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-6-(phenylmethylene)-1,2,4,5,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one 0
            (4aS,7R)-7-ethenyl-4b,10-dihydroxy-1,1,4a,7-tetramethyl-3,4,5,6-tetrahydro-2H-phenanthren-9-one 0
            (R)-resistoflavin 0
            1,4,6b,7,10-pentahydroxy-1,2,6b,7,8,12b-hexahydroperylene-3,9-dione 0
            1,4-Dimethylphenanthrene 0
            1-(2-phenanthrenyl)ethanone 0
            1-(phenanthren-2-ylcarbonyl)piperazine-2,3-dicarboxylic acid + 0
            1-deoxy-2-demethyl-viridiol 0
            1-deoxyviridiol 0
            1-methoxyphenanthrene 0
            1-methylphenanthrene 25
            11H-Benz[bc]aceanthrylene 0
            12-Methoxy-8,11,13-abietatrien-20,11-olide 0
            12-demethylmulticaulin 0
            12-demethylmultiorthoquinone 0
            12beta-chloro-3,9alpha,11beta,13beta,16-pentahydroxy-8,9,10,11,12,13-hexahydro-6(7H)-one 0
            16-O-sulfo-18-norisopimar-7-en-4alpha,16-diol 0
            1a,11b-Dihydro-4,9-dimethylbenz[a]anthra[3,4-b]oxirene 0
            2,3,5,7-Tetramethoxy-9,10-dihydrophenanthrene 0
            2,3-Dehydro-UWM6 0
            2-(Benzyloxy)-1-(2-methoxy-1-naphthyl)phenanthrene 0
            3,11-dihydroxy-13-methoxy-5-methyl-19-oxapentacyclo[8.8.1.01,10.02,7.012,17]nonadeca-2(7),3,5,8,12(17),13,15-heptaen-18-one 0
            3,6a,9,10-tetrahydroxy-7,8-epoxy-4-oxo-4,5,6,6a,6b,7,8,9-octahydroperylene 0
            3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one 0
            3-(dibutylamino)-1-[1,3-dichloro-6-(trifluoromethyl)-9-phenanthrenyl]-1-propanol 0
            3-Nitrobenzanthrone 135
            3-Nitroperylene 1
            4,8,10,14-tetramethyl-6-acetoxy-14-[16-acetoxy-19-(20,21-dimethyl)-18-ene]phenanthrene-1-ene-3,7-dione 0
            4-[[3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-yl]amino]-4-oxo-2-butenoic acid methyl ester 0
            4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one 0
            5,6-Cyclopenteno-1,2-benzanthracene 0
            6-Alpha Naloxol 0
            6-beta-Naltrexol 0
            6-methoxy-3,6a,9,10-tetrahydroxy-7,8-epoxy-4-oxo-4,5,6,6a,6b,7,8,9-octahydroperylene 0
            6alpha-Naltrexol 0
            6alpha-Oxycodol N-oxide 0
            7,8-Dihydropyrene-8-carboxylate 0
            7-Benzylidenenaltrexone 1
            7-Hydroxymethyl-12-methylbenz[a]anthracene 0
            7-Hydroxymethyl-12-methylbenz[a]anthracene sulfate 0
            7-Nitrobenz[a]anthracene 3
            7-benzo[a]phenalenone 0
            7-ethenyl-4b-hydroxy-1,1,7-trimethyl-9-oxo-3,4,5,6,10,10a-hexahydro-2H-phenanthrene-4a-carboxylic acid 0
            7beta,9alpha-dihydroxypimara-8(14),15-diene 0
            9,10-Dihydro-2,3,5,7-Phenanthrenetetrol 0
            9,10-phenanthroquinone 37
            9a-Hydroxy-1,8(14),15-isopimaratrien-3,11-dione 0
            9a-hydroxy-1,8(14),15-isopimaratrien-3,7,11-trione 0
            A-74528 0
            Actinomadurol 0
            Aflavazole 0
            Altercrasin D 0
            Altercrasin E 0
            Alterperylenepoxide A 0
            Altertoxin I 1
            Altertoxin III 0
            Altertoxin IV 0
            Arenatin B 0
            Arenatin C 0
            Arthrinin A 0
            Arthrinin B 0
            Arthrinin C 0
            Arthrinin D 0
            Aspewentin C 0
            Aspewentin D 0
            Aspewentin E 0
            Aspewentin F 0
            Aspewentin I 0
            Aspewentin J 0
            Aspewentin K 0
            Aspewentin L 0
            Azicemicin A 0
            Azicemicin B 0
            Benastatin B 0
            Benz[j]aceanthrylene 1
            Benz[l]aceanthrylene 0
            Benzo[a]pyrene-11,12-epoxide 0
            Benzo[ghi]fluoranthene 0
            Blighinone 0
            Botrysphin E 0
            Botrysphin I 0
            Bromosphaerone 0
            C1'-C9-Glycosylated UWM6 0
            Cepharatine A, (rel)- 0
            Coelogin 0
            Demethoxyviridin 0
            Demethoxyviridiol 0
            Desmethoxyviridiol 0
            Dibenz[a,j]anthracene 2
            Dibenzo[a,e]fluoranthene 0
            Dihydrocelastryl diacetate 0
            Fischambiguine A 0
            Fischambiguine B 0
            Flavidin 0
            Gancaonin U 0
            Gancaonin V 0
            Gifhornenolone A 0
            Griseorhodin D1/D2 0
            Halofantrine 1
            Haloquinone 0
            Hircinol 0
            Hovenolactone 0
            Hydroxybutorphanol 0
            JBIR-65 0
            K4610422 0
            Kiamycin 0
            Kiamycin C 0
            LSM-1645 0
            Libertellenone B 0
            Loroglossol 0
            Lucensimycin A 0
            Lucensimycin B 0
            Lucensimycin D 0
            Minimoidione A 0
            Murayaquinone 0
            Murayaquinone C 0
            Murayaquinone D 0
            Murayaquinone E 0
            N,N-dimethyl-1-(2-methyl-3-phenanthrenyl)methanamine 0
            N-[(4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-ylidene)amino]benzamide 0
            Naphtho[2,1-a]fluoranthene 0
            Nodulisporiviridin E 0
            Norbuprenorphine 2
            Norbutorphanol 0
            Noroxycodone 1
            Noroxycodone-d3 0
            Noroxymorphone 0
            OSU-03012 2
            Opened gamma-lactone ring of libertellenone M 0
            Orchinol 0
            Oxymorphone hydrochloride 0
            Petromindole 0
            Phenanthrene-4,5-dicarboxylate 0
            Phenanthrene-4-carboxylate 0
            Piloquinone 0
            Polysiphenol 0
            Prejadomycin 2-carboxylate 0
            Pristimerol 0
            Pyrene-1,2-oxide 0
            Pyrene-4,5-oxide 0
            Resistoflavine 0
            Samidorphan 0
            Scopararane D 0
            Scopararane E 0
            Scopararane G 0
            Scopararane H 0
            Solanolone 0
            Sphaeropsidin G 0
            Taichunin D 0
            Talascortene C 0
            Tubingensin A 0
            UWM6 0
            Uncinatone 0
            Verrulactone C 0
            Viridin 0
            Viridiol 0
            Xylarinorditerpene I 0
            Xylarinorditerpene J 0
            Xylarinorditerpene L 0
            Xylarinorditerpene O 0
            Xylarinorditerpene P 0
            Xylarinorditerpene Q 0
            Zafrin 0
            alpha-noroxycodol 0
            alpha-oxycodol 0
            bagrosin 0
            beta-noroxycodol 0
            beta-oxymorphol 0
            chrysene-1,4-dione 0
            cis-4,5-Dihydroxy-4,5-dihydropyrene 0
            dihydrophenanthrene + 0
            dihydrophenanthrenediol + 0
            methylnaltrexone 1
            multicaulin 0
            multiorthoquinone 0
            nalfurafine 0
            nor-6-Oxycodol 0
            oleoyl danshenxinkun A 0
            phenanthrene + 123
            phenanthrene oxide + 1
            phenanthrenediol + 0
            phenanthrenediyl bissulfate + 0
            phenanthrol + 35
            phenanthryl beta-D-glucopyranoside + 0
            phenanthryl monosulfate + 0
            thalicpureine 0
            trans-4,5-Dihydroxy-4,5-dihydropyrene 0
            trans-5,6-Dihydro-5,6-dihydroxy-7,12-dimethylbenz[a]anthracene 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      carbon group element atom 19757
                        carbon atom 19754
                          organic molecular entity 19754
                            organic molecule 19706
                              organic cyclic compound 19495
                                carbocyclic compound 18584
                                  carbopolycyclic compound 17183
                                    carbotricyclic compound 1558
                                      phenanthrenes 303
                                        (+)-Eurotone A 0
                                        (+)-murayaquinone B 0
                                        (+)-variecolortin B 0
                                        (+/-)-variecolortin B 0
                                        (+/-)-variecolortin C 0
                                        (-)-Eurotone A 0
                                        (-)-murayaquinone B 0
                                        (-)-variecolortin C 0
                                        (1R,4R,4aR,4bS,7R)-7-ethenyl-4,4b,10-trihydroxy-1,4a,7-trimethyl-9-oxo-3,4,5,6-tetrahydro-2H-phenanthrene-1-carboxylic acid 0
                                        (3R)-3,7,8-trihydroxy-3-methyl-4,5-dihydro-2H-benzo[a]anthracene-1,6-dione 0
                                        (4R,4aS,12bS)-3-(cyclobutylmethyl)-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,7,9-triol 0
                                        (4R,4aS,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one 0
                                        (4R,4aS,7S,12bS)-3-(cyclobutylmethyl)-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,7,9-triol 0
                                        (4R,4aS,7aR)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one 0
                                        (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-6-(phenylmethylene)-1,2,4,5,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one 0
                                        (4aS,7R)-7-ethenyl-4b,10-dihydroxy-1,1,4a,7-tetramethyl-3,4,5,6-tetrahydro-2H-phenanthren-9-one 0
                                        (R)-resistoflavin 0
                                        1,4,6b,7,10-pentahydroxy-1,2,6b,7,8,12b-hexahydroperylene-3,9-dione 0
                                        1,4-Dimethylphenanthrene 0
                                        1-(2-phenanthrenyl)ethanone 0
                                        1-(phenanthren-2-ylcarbonyl)piperazine-2,3-dicarboxylic acid + 0
                                        1-deoxy-2-demethyl-viridiol 0
                                        1-deoxyviridiol 0
                                        1-methoxyphenanthrene 0
                                        1-methylphenanthrene 25
                                        11H-Benz[bc]aceanthrylene 0
                                        12-Methoxy-8,11,13-abietatrien-20,11-olide 0
                                        12-demethylmulticaulin 0
                                        12-demethylmultiorthoquinone 0
                                        12beta-chloro-3,9alpha,11beta,13beta,16-pentahydroxy-8,9,10,11,12,13-hexahydro-6(7H)-one 0
                                        16-O-sulfo-18-norisopimar-7-en-4alpha,16-diol 0
                                        1a,11b-Dihydro-4,9-dimethylbenz[a]anthra[3,4-b]oxirene 0
                                        2,3,5,7-Tetramethoxy-9,10-dihydrophenanthrene 0
                                        2,3-Dehydro-UWM6 0
                                        2-(Benzyloxy)-1-(2-methoxy-1-naphthyl)phenanthrene 0
                                        3,11-dihydroxy-13-methoxy-5-methyl-19-oxapentacyclo[8.8.1.01,10.02,7.012,17]nonadeca-2(7),3,5,8,12(17),13,15-heptaen-18-one 0
                                        3,6a,9,10-tetrahydroxy-7,8-epoxy-4-oxo-4,5,6,6a,6b,7,8,9-octahydroperylene 0
                                        3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one 0
                                        3-(dibutylamino)-1-[1,3-dichloro-6-(trifluoromethyl)-9-phenanthrenyl]-1-propanol 0
                                        3-Nitrobenzanthrone 135
                                        3-Nitroperylene 1
                                        4,8,10,14-tetramethyl-6-acetoxy-14-[16-acetoxy-19-(20,21-dimethyl)-18-ene]phenanthrene-1-ene-3,7-dione 0
                                        4-[[3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-yl]amino]-4-oxo-2-butenoic acid methyl ester 0
                                        4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one 0
                                        5,6-Cyclopenteno-1,2-benzanthracene 0
                                        6-Alpha Naloxol 0
                                        6-beta-Naltrexol 0
                                        6-methoxy-3,6a,9,10-tetrahydroxy-7,8-epoxy-4-oxo-4,5,6,6a,6b,7,8,9-octahydroperylene 0
                                        6alpha-Naltrexol 0
                                        6alpha-Oxycodol N-oxide 0
                                        7,8-Dihydropyrene-8-carboxylate 0
                                        7-Benzylidenenaltrexone 1
                                        7-Hydroxymethyl-12-methylbenz[a]anthracene 0
                                        7-Hydroxymethyl-12-methylbenz[a]anthracene sulfate 0
                                        7-Nitrobenz[a]anthracene 3
                                        7-benzo[a]phenalenone 0
                                        7-ethenyl-4b-hydroxy-1,1,7-trimethyl-9-oxo-3,4,5,6,10,10a-hexahydro-2H-phenanthrene-4a-carboxylic acid 0
                                        7beta,9alpha-dihydroxypimara-8(14),15-diene 0
                                        9,10-Dihydro-2,3,5,7-Phenanthrenetetrol 0
                                        9,10-phenanthroquinone 37
                                        9a-Hydroxy-1,8(14),15-isopimaratrien-3,11-dione 0
                                        9a-hydroxy-1,8(14),15-isopimaratrien-3,7,11-trione 0
                                        A-74528 0
                                        Actinomadurol 0
                                        Aflavazole 0
                                        Altercrasin D 0
                                        Altercrasin E 0
                                        Alterperylenepoxide A 0
                                        Altertoxin I 1
                                        Altertoxin III 0
                                        Altertoxin IV 0
                                        Arenatin B 0
                                        Arenatin C 0
                                        Arthrinin A 0
                                        Arthrinin B 0
                                        Arthrinin C 0
                                        Arthrinin D 0
                                        Aspewentin C 0
                                        Aspewentin D 0
                                        Aspewentin E 0
                                        Aspewentin F 0
                                        Aspewentin I 0
                                        Aspewentin J 0
                                        Aspewentin K 0
                                        Aspewentin L 0
                                        Azicemicin A 0
                                        Azicemicin B 0
                                        Benastatin B 0
                                        Benz[j]aceanthrylene 1
                                        Benz[l]aceanthrylene 0
                                        Benzo[a]pyrene-11,12-epoxide 0
                                        Benzo[ghi]fluoranthene 0
                                        Blighinone 0
                                        Botrysphin E 0
                                        Botrysphin I 0
                                        Bromosphaerone 0
                                        C1'-C9-Glycosylated UWM6 0
                                        Cepharatine A, (rel)- 0
                                        Coelogin 0
                                        Demethoxyviridin 0
                                        Demethoxyviridiol 0
                                        Desmethoxyviridiol 0
                                        Dibenz[a,j]anthracene 2
                                        Dibenzo[a,e]fluoranthene 0
                                        Dihydrocelastryl diacetate 0
                                        Fischambiguine A 0
                                        Fischambiguine B 0
                                        Flavidin 0
                                        Gancaonin U 0
                                        Gancaonin V 0
                                        Gifhornenolone A 0
                                        Griseorhodin D1/D2 0
                                        Halofantrine 1
                                        Haloquinone 0
                                        Hircinol 0
                                        Hovenolactone 0
                                        Hydroxybutorphanol 0
                                        JBIR-65 0
                                        K4610422 0
                                        Kiamycin 0
                                        Kiamycin C 0
                                        LSM-1645 0
                                        Libertellenone B 0
                                        Loroglossol 0
                                        Lucensimycin A 0
                                        Lucensimycin B 0
                                        Lucensimycin D 0
                                        Minimoidione A 0
                                        Murayaquinone 0
                                        Murayaquinone C 0
                                        Murayaquinone D 0
                                        Murayaquinone E 0
                                        N,N-dimethyl-1-(2-methyl-3-phenanthrenyl)methanamine 0
                                        N-[(4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-ylidene)amino]benzamide 0
                                        Naphtho[2,1-a]fluoranthene 0
                                        Nodulisporiviridin E 0
                                        Norbuprenorphine 2
                                        Norbutorphanol 0
                                        Noroxycodone 1
                                        Noroxycodone-d3 0
                                        Noroxymorphone 0
                                        OSU-03012 2
                                        Opened gamma-lactone ring of libertellenone M 0
                                        Orchinol 0
                                        Oxymorphone hydrochloride 0
                                        Petromindole 0
                                        Phenanthrene-4,5-dicarboxylate 0
                                        Phenanthrene-4-carboxylate 0
                                        Piloquinone 0
                                        Polysiphenol 0
                                        Prejadomycin 2-carboxylate 0
                                        Pristimerol 0
                                        Pyrene-1,2-oxide 0
                                        Pyrene-4,5-oxide 0
                                        Resistoflavine 0
                                        Samidorphan 0
                                        Scopararane D 0
                                        Scopararane E 0
                                        Scopararane G 0
                                        Scopararane H 0
                                        Solanolone 0
                                        Sphaeropsidin G 0
                                        Taichunin D 0
                                        Talascortene C 0
                                        Tubingensin A 0
                                        UWM6 0
                                        Uncinatone 0
                                        Verrulactone C 0
                                        Viridin 0
                                        Viridiol 0
                                        Xylarinorditerpene I 0
                                        Xylarinorditerpene J 0
                                        Xylarinorditerpene L 0
                                        Xylarinorditerpene O 0
                                        Xylarinorditerpene P 0
                                        Xylarinorditerpene Q 0
                                        Zafrin 0
                                        alpha-noroxycodol 0
                                        alpha-oxycodol 0
                                        bagrosin 0
                                        beta-noroxycodol 0
                                        beta-oxymorphol 0
                                        chrysene-1,4-dione 0
                                        cis-4,5-Dihydroxy-4,5-dihydropyrene 0
                                        dihydrophenanthrene + 0
                                        dihydrophenanthrenediol + 0
                                        methylnaltrexone 1
                                        multicaulin 0
                                        multiorthoquinone 0
                                        nalfurafine 0
                                        nor-6-Oxycodol 0
                                        oleoyl danshenxinkun A 0
                                        phenanthrene + 123
                                        phenanthrene oxide + 1
                                        phenanthrenediol + 0
                                        phenanthrenediyl bissulfate + 0
                                        phenanthrol + 35
                                        phenanthryl beta-D-glucopyranoside + 0
                                        phenanthryl monosulfate + 0
                                        thalicpureine 0
                                        trans-4,5-Dihydroxy-4,5-dihydropyrene 0
                                        trans-5,6-Dihydro-5,6-dihydroxy-7,12-dimethylbenz[a]anthracene 0
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