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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:pentose
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Accession:CHEBI:25901 term browser browse the term
Definition:A five-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldopentose) or a ketone group at position 2 (ketopentose).
Synonyms:related_synonym: pentoses


show annotations for term's descendants           Sort by:
aldehydo-D-ribose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor multiple interactions
increases expression 		ISO [Ribose co-treated with Glucose] results in increased expression of AGER protein; AGER protein affects the reaction [Ribose promotes the reaction [Glucose results in increased phosphorylation of RELA protein]]
Ribose results in increased expression of AGER protein 		CTD PMID:30101366 NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,151,965...4,155,685 		JBrowse link
G B2m beta-2 microglobulin increases glycation ISO Ribose results in increased glycation of B2M protein CTD PMID:21864514 NCBI chr 3:129,549,236...129,555,354
Ensembl chr 3:129,549,318...129,555,356 		JBrowse link
G Casp3 caspase 3 multiple interactions EXP [Creatine co-treated with Ribose] results in decreased activity of CASP3 protein CTD PMID:21220914 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex increases phosphorylation ISO Ribose results in increased phosphorylation of CHUK protein CTD PMID:30101366 NCBI chr 1:252,908,748...252,944,273
Ensembl chr 1:252,908,749...252,944,273 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta increases phosphorylation ISO Ribose results in increased phosphorylation of IKBKB protein CTD PMID:30101366 NCBI chr16:76,021,968...76,075,717
Ensembl chr16:76,022,008...76,081,911 		JBrowse link
G Ins1 insulin 1 increases secretion ISO Ribose results in increased secretion of INS1 protein CTD PMID:30101366 NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
increases phosphorylation 		ISO [Ribose co-treated with Glucose] results in increased phosphorylation of NFKBIA protein
Ribose results in increased phosphorylation of NFKBIA protein 		CTD PMID:30101366 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072 		JBrowse link
G Oat ornithine aminotransferase multiple interactions EXP Ribose inhibits the reaction [Cyclic AMP results in increased activity of OAT protein] CTD PMID:2827574 NCBI chr 1:196,777,973...196,797,754
Ensembl chr 1:196,777,975...196,797,754 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases phosphorylation
multiple interactions 		ISO Ribose results in increased phosphorylation of RELA protein
[Ribose co-treated with Glucose] affects the localization of RELA protein; AGER protein affects the reaction [Ribose promotes the reaction [Glucose results in increased phosphorylation of RELA protein]]; Ribose promotes the reaction [Glucose results in increased phosphorylation of RELA protein] 		CTD PMID:30101366 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
D-ribofuranose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor multiple interactions
increases expression 		ISO [Ribose co-treated with Glucose] results in increased expression of AGER protein; AGER protein affects the reaction [Ribose promotes the reaction [Glucose results in increased phosphorylation of RELA protein]]
Ribose results in increased expression of AGER protein 		CTD PMID:30101366 NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,151,965...4,155,685 		JBrowse link
G B2m beta-2 microglobulin increases glycation ISO Ribose results in increased glycation of B2M protein CTD PMID:21864514 NCBI chr 3:129,549,236...129,555,354
Ensembl chr 3:129,549,318...129,555,356 		JBrowse link
G Casp3 caspase 3 multiple interactions EXP [Creatine co-treated with Ribose] results in decreased activity of CASP3 protein CTD PMID:21220914 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex increases phosphorylation ISO Ribose results in increased phosphorylation of CHUK protein CTD PMID:30101366 NCBI chr 1:252,908,748...252,944,273
Ensembl chr 1:252,908,749...252,944,273 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta increases phosphorylation ISO Ribose results in increased phosphorylation of IKBKB protein CTD PMID:30101366 NCBI chr16:76,021,968...76,075,717
Ensembl chr16:76,022,008...76,081,911 		JBrowse link
G Ins1 insulin 1 increases secretion ISO Ribose results in increased secretion of INS1 protein CTD PMID:30101366 NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682 		JBrowse link
G Nfkbia NFKB inhibitor alpha increases phosphorylation
multiple interactions 		ISO Ribose results in increased phosphorylation of NFKBIA protein
[Ribose co-treated with Glucose] results in increased phosphorylation of NFKBIA protein 		CTD PMID:30101366 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072 		JBrowse link
G Oat ornithine aminotransferase multiple interactions EXP Ribose inhibits the reaction [Cyclic AMP results in increased activity of OAT protein] CTD PMID:2827574 NCBI chr 1:196,777,973...196,797,754
Ensembl chr 1:196,777,975...196,797,754 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases phosphorylation 		ISO [Ribose co-treated with Glucose] affects the localization of RELA protein; AGER protein affects the reaction [Ribose promotes the reaction [Glucose results in increased phosphorylation of RELA protein]]; Ribose promotes the reaction [Glucose results in increased phosphorylation of RELA protein]
Ribose results in increased phosphorylation of RELA protein 		CTD PMID:30101366 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
royal jelly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP royal jelly inhibits the reaction [Fluorides results in decreased expression of BAX protein] CTD PMID:34227456 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO
EXP 		royal jelly inhibits the reaction [Nicotine results in decreased expression of BCL2 mRNA]
royal jelly inhibits the reaction [Fluorides results in increased expression of BCL2 protein] 		CTD PMID:30896085 PMID:34227456 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions EXP royal jelly inhibits the reaction [Fluorides results in decreased expression of BDNF protein] CTD PMID:34227456 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO
EXP 		royal jelly inhibits the reaction [Nicotine results in increased expression of CASP3 mRNA]
royal jelly inhibits the reaction [Fluorides results in decreased expression of CASP3 protein] 		CTD PMID:30896085 PMID:34227456 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp6 caspase 6 multiple interactions EXP royal jelly inhibits the reaction [Fluorides results in decreased expression of CASP6 protein] CTD PMID:34227456 NCBI chr 2:221,140,287...221,152,727
Ensembl chr 2:221,140,256...221,152,726 		JBrowse link
G Casp9 caspase 9 multiple interactions EXP royal jelly inhibits the reaction [Fluorides results in decreased expression of CASP9 protein] CTD PMID:34227456 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cat catalase multiple interactions EXP
ISO 		royal jelly inhibits the reaction [Cisplatin results in decreased activity of CAT protein]; royal jelly inhibits the reaction [Fluorides results in decreased activity of CAT protein]; royal jelly inhibits the reaction [Tartrazine results in decreased activity of CAT protein]
royal jelly inhibits the reaction [Nicotine results in decreased activity of CAT protein] 		CTD PMID:20369241 PMID:26190785 PMID:30896085 PMID:34227456 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO royal jelly inhibits the reaction [phenylhydrazine affects the expression of CCND1 mRNA] CTD PMID:35099105 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810 		JBrowse link
G E2f1 E2F transcription factor 1 multiple interactions EXP royal jelly inhibits the reaction [Paclitaxel results in increased expression of E2F1 mRNA] CTD PMID:27496854 NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:163,524,739...163,535,563 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
affects binding
increases activity 		ISO Estradiol inhibits the reaction [royal jelly binds to ESR1 protein]; royal jelly binds to and results in increased activity of ESR1 protein; royal jelly inhibits the reaction [Estradiol binds to ESR1 protein]
royal jelly results in increased activity of ESR1 protein 		CTD PMID:15946813 PMID:17287592 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
affects binding 		ISO Estradiol inhibits the reaction [royal jelly binds to ESR2 protein]; royal jelly binds to and results in increased activity of ESR2 protein; royal jelly inhibits the reaction [Estradiol binds to ESR2 protein] CTD PMID:15946813 PMID:17287592 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions EXP royal jelly inhibits the reaction [Fluorides results in increased expression of GSK3B protein] CTD PMID:34227456 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249 		JBrowse link
G Ins1 insulin 1 multiple interactions EXP royal jelly inhibits the reaction [Fructose results in increased expression of INS1 protein] CTD PMID:18981581 NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
decreases expression 		ISO
EXP 		royal jelly inhibits the reaction [phenylhydrazine results in decreased expression of MYC mRNA]
royal jelly results in decreased expression of MYC mRNA
royal jelly inhibits the reaction [Paclitaxel results in decreased expression of MYC mRNA] 		CTD PMID:27496854 PMID:35099105 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP royal jelly inhibits the reaction [Fluorides results in decreased expression of NFE2L2 protein] CTD PMID:34227456 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO royal jelly inhibits the reaction [Nicotine results in decreased expression of PCNA protein] CTD PMID:30896085 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP royal jelly inhibits the reaction [Fluorides results in increased expression of RELA protein] CTD PMID:34227456 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Tff1 trefoil factor 1 increases expression ISO royal jelly results in increased expression of TFF1 mRNA CTD PMID:15946813 NCBI chr20:9,237,095...9,240,956
Ensembl chr20:9,237,095...9,240,956 		JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO royal jelly inhibits the reaction [Nicotine results in increased expression of TRP53 mRNA] CTD PMID:30896085 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO
EXP 		royal jelly results in increased expression of VEGFA mRNA CTD PMID:15946813 PMID:17287592 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
xylose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lct lactase increases hydrolysis EXP LCT protein results in increased hydrolysis of Xylose CTD PMID:14701853 NCBI chr13:42,334,347...42,376,872
Ensembl chr13:42,334,347...42,376,872 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression ISO Xylose results in increased expression of SREBF1 mRNA CTD PMID:10913129 NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164 		JBrowse link
xylulose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dcxr dicarbonyl and L-xylulose reductase multiple interactions
increases metabolic processing 		ISO [DCXR protein co-treated with NAD] results in increased reduction of Xylulose; [DCXR protein co-treated with NADP] results in increased reduction of Xylulose; [DCXR protein results in increased metabolism of Xylulose] which results in increased chemical synthesis of Xylitol CTD PMID:28595002 NCBI chr10:106,504,730...106,506,619 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20874
    chemical entity 20872
      atom 20872
        nonmetal atom 20781
          oxygen atom 20437
            oxygen molecular entity 20437
              organooxygen compound 19713
                carbohydrates and carbohydrate derivatives 15263
                  carbohydrate 6585
                    monosaccharide 2561
                      pentose 29
                        (2S,4R,5S)-Muscarine 0
                        (3R,4R)-Oxolane-2,3,4-triol 0
                        (3R,4R,5R)-3-Fluoro-5-(hydroxymethyl)oxolane-2,3,4-triol 0
                        (3S,4R)-Oxolane-2,3,4-triol 0
                        (3S,4S)-2-(Hydroxymethyl)oxolane-2,3,4-triol 0
                        1-(methylthio)ribulose 5-phosphate(2-) 0
                        1-Deoxy-1-(nonylamino)pentitol 0
                        1-S-Hexyl-1-thiopentitol 0
                        1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxypyrimidin-2-one 0
                        2,3,4,5-tetrahydroxypentanal 0
                        2-O-Methyl-D-xylose 0
                        3-o-methyl-l-xylose 0
                        5,6-Dihydro-5'-azacytidine 0
                        5-Methylthioribose 1-phosphate 0
                        D-1-Deoxy-erythro-hexo-2,3-diulose 0
                        D-xylulofuranose + 0
                        Epimuscarine 0
                        Lyxulose 0
                        Micromonohalimane B 0
                        Ribose-1-arsenate 0
                        Suillumide 0
                        U-44590 0
                        Varioxiranol K 0
                        aldopentose + 28
                        alpha-D-xylofuranose 0
                        ketoaldopentose + 0
                        ketopentose + 1
                        pentofuranose 0
                        sacrotride A 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20874
    subatomic particle 20883
      composite particle 20883
        hadron 20872
          baryon 20883
            nucleon 20872
              atomic nucleus 20883
                atom 20872
                  main group element atom 20796
                    p-block element atom 20796
                      carbon group element atom 20712
                        carbon atom 20706
                          organic molecular entity 20706
                            heteroorganic entity 20201
                              organochalcogen compound 19822
                                organooxygen compound 19713
                                  carbohydrates and carbohydrate derivatives 15263
                                    carbohydrate 6585
                                      monosaccharide 2561
                                        pentose 29
                                          (2S,4R,5S)-Muscarine 0
                                          (3R,4R)-Oxolane-2,3,4-triol 0
                                          (3R,4R,5R)-3-Fluoro-5-(hydroxymethyl)oxolane-2,3,4-triol 0
                                          (3S,4R)-Oxolane-2,3,4-triol 0
                                          (3S,4S)-2-(Hydroxymethyl)oxolane-2,3,4-triol 0
                                          1-(methylthio)ribulose 5-phosphate(2-) 0
                                          1-Deoxy-1-(nonylamino)pentitol 0
                                          1-S-Hexyl-1-thiopentitol 0
                                          1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxypyrimidin-2-one 0
                                          2,3,4,5-tetrahydroxypentanal 0
                                          2-O-Methyl-D-xylose 0
                                          3-o-methyl-l-xylose 0
                                          5,6-Dihydro-5'-azacytidine 0
                                          5-Methylthioribose 1-phosphate 0
                                          D-1-Deoxy-erythro-hexo-2,3-diulose 0
                                          D-xylulofuranose + 0
                                          Epimuscarine 0
                                          Lyxulose 0
                                          Micromonohalimane B 0
                                          Ribose-1-arsenate 0
                                          Suillumide 0
                                          U-44590 0
                                          Varioxiranol K 0
                                          aldopentose + 28
                                          alpha-D-xylofuranose 0
                                          ketoaldopentose + 0
                                          ketopentose + 1
                                          pentofuranose 0
                                          sacrotride A 0
paths to the root