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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:oxime
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Accession:CHEBI:25750 term browser browse the term
Definition:Compounds of structure R2C=NOH derived from condensation of aldehydes or ketones with hydroxylamine. Oximes from aldehydes may be called aldoximes; those from ketones may be called ketoximes.
Synonyms:related_synonym: Formula=CHNOR2;   SMILES=O\\N=C(\\[*])[*];   oximes
 cyclic_relationship: is_conjugate_acid_of CHEBI:142513



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6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [[NR1I3 protein binds to RXRA protein] which binds to ABCG2 promoter]; [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with NR1I3 protein] results in increased expression of ABCG2 mRNA; [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [[NR1I3 protein binds to RXRA protein] which binds to ABCG2 promoter]] which results in increased expression of ABCG2 mRNA CTD PMID:22093699 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 multiple interactions ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACAA2 mRNA CTD PMID:30611723 NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249
JBrowse link
G Acaca acetyl-CoA carboxylase alpha increases expression
multiple interactions
ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of ACACA mRNA
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of ACACA mRNA
CTD PMID:27180240 PMID:30611723 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Acacb acetyl-CoA carboxylase beta multiple interactions ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of ACACB mRNA CTD PMID:30611723 NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655
JBrowse link
G Acads acyl-CoA dehydrogenase short chain increases expression
multiple interactions
ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of ACADS mRNA
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACADS mRNA
CTD PMID:30611723 NCBI chr12:41,493,650...41,502,897
Ensembl chr12:41,493,626...41,502,898
JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 multiple interactions ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACAT1 mRNA CTD PMID:30611723 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 multiple interactions ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACAT2 mRNA CTD PMID:30611723 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
JBrowse link
G Acot1 acyl-CoA thioesterase 1 increases expression ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of ACOT1 mRNA CTD PMID:30611723 NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
JBrowse link
G Acot12 acyl-CoA thioesterase 12 multiple interactions ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACOT12 mRNA CTD PMID:30611723 NCBI chr 2:22,986,867...23,027,538
Ensembl chr 2:22,986,626...23,027,536
JBrowse link
G Acot4 acyl-CoA thioesterase 4 increases expression
multiple interactions
ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of ACOT4 mRNA
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACOT4 mRNA
CTD PMID:30611723 NCBI chr 6:103,668,699...103,674,037
Ensembl chr 6:103,668,753...103,673,917
JBrowse link
G Acot6 acyl-CoA thioesterase 6 multiple interactions
increases expression
ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACOT6 mRNA
6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of ACOT6 mRNA
CTD PMID:30611723 NCBI chr 6:103,732,372...103,741,446
Ensembl chr 6:103,732,372...103,741,446
JBrowse link
G Acot7 acyl-CoA thioesterase 7 multiple interactions
increases expression
ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACOT7 mRNA
6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of ACOT7 mRNA
CTD PMID:30611723 NCBI chr 5:162,686,562...162,779,309
Ensembl chr 5:162,684,645...162,779,309
JBrowse link
G Acot8 acyl-CoA thioesterase 8 multiple interactions ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of ACOT8 mRNA CTD PMID:30611723 NCBI chr 3:153,531,192...153,542,851
Ensembl chr 3:153,531,193...153,542,851
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 multiple interactions ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACSL5 mRNA CTD PMID:30611723 NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607
JBrowse link
G Agpat1 1-acylglycerol-3-phosphate O-acyltransferase 1 increases expression ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of AGPAT1 mRNA CTD PMID:30611723 NCBI chr20:4,135,955...4,144,880
Ensembl chr20:4,135,957...4,145,278
JBrowse link
G Agpat2 1-acylglycerol-3-phosphate O-acyltransferase 2 increases expression
multiple interactions
ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of AGPAT2 mRNA
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of AGPAT2 mRNA
CTD PMID:30611723 NCBI chr 3:9,416,837...9,428,567
Ensembl chr 3:9,416,843...9,428,371
JBrowse link
G Apoa5 apolipoprotein A5 multiple interactions ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of APOA5 mRNA CTD PMID:30611723 NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816
JBrowse link
G Apob apolipoprotein B multiple interactions ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of APOB mRNA CTD PMID:30611723 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
JBrowse link
G Apoc4 apolipoprotein C4 multiple interactions ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of APOC4 mRNA CTD PMID:30611723 NCBI chr 1:79,335,745...79,339,942
Ensembl chr 1:79,335,745...79,339,981
JBrowse link
G Cd36 CD36 molecule increases expression
multiple interactions
ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CD36 mRNA
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of CD36 mRNA
CTD PMID:30611723 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 increases expression
multiple interactions
ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CPT2 mRNA
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of CPT2 mRNA
CTD PMID:30611723 NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions
increases expression
increases activity
ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [NR1I3 protein results in increased expression of CYP2B10 mRNA]; [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime binds to and results in increased activity of NR1I3 protein] which results in increased expression of CYP2B6 mRNA; [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Anisomycin co-treated with NR1I3 protein] results in increased expression of CYP2B6 mRNA; [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with NR1I3 protein alternative form] results in increased expression of CYP2B6 mRNA; [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with NR1I3 protein mutant form] results in increased expression of CYP2B6 mRNA; [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of CYP2B6 mRNA; [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein] which results in increased expression of CYP2B6 mRNA; [Progesterone co-treated with Estradiol] inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]; allyl isothiocyanate inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of CYP2B6 protein]; allyl isothiocyanate inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]; allyl isothiocyanate inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 protein]; allyl isothiocyanate inhibits the reaction [NR1I3 protein promotes the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]; Estradiol inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]; ethyl (5-(diethylglycyl)-10,11-dihydro-5H-dibenzo(b,f)azepin-3-yl)carbamate inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]; GW 3965 inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]; Imidazoles inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]; Imidazoles inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 protein]; Ketoconazole inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]; lactacystin inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]; NR0B1 protein inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6]; NR1I3 mutant form inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]; NR1I3 mutant form inhibits the reaction [Estradiol inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]]; NR1I3 mutant form inhibits the reaction [Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]]; NR1I3 protein promotes the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]; Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]
6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B10 mRNA; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 protein
CTD PMID:16608920 PMID:17483497 PMID:18332078 PMID:18468591 PMID:19202563 More... NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 increases expression ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2C55 mRNA CTD PMID:28541575 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 affects binding
increases expression
ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime binds to NR1I3 protein] which binds to CYP2C8 promoter
6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2C8 mRNA
CTD PMID:15933212
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of CYP2E1 mRNA CTD PMID:30611723 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
increases expression
increases activity
ISO allyl isothiocyanate inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP3A4 mRNA]; allyl isothiocyanate inhibits the reaction [NR1I3 protein promotes the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP3A4 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP3A4 mRNA]; Imidazoles inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP3A4 mRNA]; Imidazoles inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP3A4 protein]; Ketoconazole inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP3A4 mRNA]; lactacystin inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP3A4 mRNA]; NR1I3 protein promotes the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP3A4 mRNA]
6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP3A4 mRNA; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP3A4 protein
6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of CYP3A4 protein
CTD PMID:16608920 PMID:18332078 PMID:21227907 PMID:21315811 PMID:21778469 More... NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 multiple interactions ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of DECR1 mRNA CTD PMID:30611723 NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase multiple interactions ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein] which results in increased expression of DHCR24 mRNA CTD PMID:22101211 NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137
JBrowse link
G Egf epidermal growth factor multiple interactions ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:25625231 PMID:30364229 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:25625231 PMID:30364229 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 increases expression ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of ELOVL1 mRNA CTD PMID:30611723 NCBI chr 5:131,961,478...131,965,961
Ensembl chr 5:131,961,322...131,965,958
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 increases expression ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of ELOVL6 mRNA CTD PMID:30611723 NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
JBrowse link
G Fabp1 fatty acid binding protein 1 multiple interactions ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of FABP1 mRNA CTD PMID:30611723 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
JBrowse link
G Fasn fatty acid synthase decreases expression
affects expression
multiple interactions
ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of FASN mRNA
6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime affects the expression of FASN mRNA
[Colforsin co-treated with 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime] results in increased expression of FASN mRNA
CTD PMID:30364229 PMID:31312845 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 multiple interactions ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of FDFT1 mRNA CTD PMID:30611723 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
JBrowse link
G Fdps farnesyl diphosphate synthase multiple interactions ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of FDPS mRNA CTD PMID:30611723 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime inhibits the reaction [FOXO1 protein binds to G6PC1 promoter]; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [[NR1I3 protein co-treated with FOXO1 protein co-treated with HNF4A protein co-treated with NCOA1 protein] binds to CYP2C9 promoter]; [Progesterone co-treated with Estradiol] inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [[NR1I3 protein co-treated with FOXO1 protein co-treated with HNF4A protein co-treated with NCOA1 protein] binds to CYP2C9 promoter]]; Estradiol inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime inhibits the reaction [FOXO1 protein binds to G6PC1 promoter]]; Estradiol inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [[NR1I3 protein co-treated with FOXO1 protein co-treated with HNF4A protein co-treated with NCOA1 protein] binds to CYP2C9 promoter]]; Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime inhibits the reaction [FOXO1 protein binds to G6PC1 promoter]]; Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [[NR1I3 protein co-treated with FOXO1 protein co-treated with HNF4A protein co-treated with NCOA1 protein] binds to CYP2C9 promoter]]; Progesterone promotes the reaction [Estradiol inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime inhibits the reaction [FOXO1 protein binds to G6PC1 promoter]]] CTD PMID:21768169 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions
increases expression
decreases expression
ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime inhibits the reaction [FOXO1 protein binds to G6PC1 promoter]; [Progesterone co-treated with Estradiol] inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of G6PC1 mRNA]; Estradiol inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime inhibits the reaction [FOXO1 protein binds to G6PC1 promoter]]; Estradiol inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of G6PC1 mRNA]; NR1I3 mutant form inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of G6PC1 mRNA]; NR1I3 mutant form inhibits the reaction [Estradiol inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of G6PC1 mRNA]]; NR1I3 mutant form inhibits the reaction [Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of G6PC1 mRNA]]; Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime inhibits the reaction [FOXO1 protein binds to G6PC1 promoter]]; Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of G6PC1 mRNA]; Progesterone promotes the reaction [Estradiol inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime inhibits the reaction [FOXO1 protein binds to G6PC1 promoter]]]
6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of G6PC1 mRNA
6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of G6PC1 mRNA; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of G6PC1 protein
CTD PMID:21768169 PMID:24878338 PMID:31312845 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 increases expression ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of GPAT3 mRNA CTD PMID:30611723 NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490
JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase multiple interactions ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of HADH mRNA CTD PMID:30611723 NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha multiple interactions ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of HADHA mRNA CTD PMID:30611723 NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta multiple interactions ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of HADHB mRNA CTD PMID:30611723 NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of HMGCR mRNA CTD PMID:30611723 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha multiple interactions ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime inhibits the reaction [HNF4A protein binds to PCK1 promoter]; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [[NR1I3 protein co-treated with FOXO1 protein co-treated with HNF4A protein co-treated with NCOA1 protein] binds to CYP2C9 promoter]; [Progesterone co-treated with Estradiol] inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [[NR1I3 protein co-treated with FOXO1 protein co-treated with HNF4A protein co-treated with NCOA1 protein] binds to CYP2C9 promoter]]; Estradiol inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime inhibits the reaction [HNF4A protein binds to PCK1 promoter]]; Estradiol inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [[NR1I3 protein co-treated with FOXO1 protein co-treated with HNF4A protein co-treated with NCOA1 protein] binds to CYP2C9 promoter]]; Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime inhibits the reaction [HNF4A protein binds to PCK1 promoter]]; Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [[NR1I3 protein co-treated with FOXO1 protein co-treated with HNF4A protein co-treated with NCOA1 protein] binds to CYP2C9 promoter]]; Progesterone promotes the reaction [Estradiol inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime inhibits the reaction [HNF4A protein binds to PCK1 promoter]]] CTD PMID:21768169 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of IL6 mRNA CTD PMID:30611723 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Lipc lipase C, hepatic type multiple interactions ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of LIPC mRNA CTD PMID:30611723 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G Lpin2 lipin 2 multiple interactions ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of LPIN2 mRNA CTD PMID:30611723 NCBI chr 9:111,083,378...111,158,193
Ensembl chr 9:111,083,745...111,158,193
JBrowse link
G Lpin3 lipin 3 multiple interactions ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of LPIN3 mRNA CTD PMID:30611723 NCBI chr 3:149,533,719...149,558,494
Ensembl chr 3:149,534,051...149,558,327
JBrowse link
G Mcat malonyl-CoA-acyl carrier protein transacylase multiple interactions ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of MCAT mRNA CTD PMID:30611723 NCBI chr 7:114,693,612...114,705,677
Ensembl chr 7:114,693,612...114,704,542
JBrowse link
G Med1 mediator complex subunit 1 multiple interactions ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [MED1 protein binds to NR1I3 protein alternative form]; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [MED1 protein binds to NR1I3 protein] CTD PMID:31312845 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299
JBrowse link
G Mlxipl MLX interacting protein-like increases expression
multiple interactions
ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of MLXIPL mRNA
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of MLXIPL mRNA
CTD PMID:27180240 PMID:30611723 NCBI chr12:21,541,608...21,577,120
Ensembl chr12:21,543,576...21,577,112
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [[NR1I3 protein co-treated with FOXO1 protein co-treated with HNF4A protein co-treated with NCOA1 protein] binds to CYP2C9 promoter]; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [NCOA1 protein binds to and results in increased activity of NR1H3 protein]; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [NCOA1 protein binds to NR1I3 protein alternative form]; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [NCOA1 protein binds to NR1I3 protein]; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [NR1I3 protein modified form binds to NCOA1 protein]; [Progesterone co-treated with Estradiol] inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [[NR1I3 protein co-treated with FOXO1 protein co-treated with HNF4A protein co-treated with NCOA1 protein] binds to CYP2C9 promoter]]; Estradiol inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [[NR1I3 protein co-treated with FOXO1 protein co-treated with HNF4A protein co-treated with NCOA1 protein] binds to CYP2C9 promoter]]; Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [[NR1I3 protein co-treated with FOXO1 protein co-treated with HNF4A protein co-treated with NCOA1 protein] binds to CYP2C9 promoter]] CTD PMID:21768169 PMID:21924250 PMID:27551952 PMID:28289823 PMID:31312845 NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664
JBrowse link
G Ncoa3 nuclear receptor coactivator 3 multiple interactions ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [NCOA3 protein binds to NR1I3 protein] CTD PMID:31312845 NCBI chr 3:154,738,566...154,821,395
Ensembl chr 3:154,738,581...154,818,594
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases activity ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NFE2L2 protein CTD PMID:30114225 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 multiple interactions ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [NR1I3 protein binds to NR0B1 protein]; NR0B1 protein inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6] CTD PMID:22896671 NCBI chr  X:50,756,886...50,761,014
Ensembl chr  X:50,756,886...50,761,011
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [NCOA1 protein binds to and results in increased activity of NR1H3 protein] CTD PMID:27551952 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of NR1H4 mRNA CTD PMID:30611723 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I2 protein CTD PMID:23899473 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 affects localization
increases activity
increases expression
affects binding
multiple interactions
decreases activity
ISO
EXP
6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime affects the localization of NR1I3 protein; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime affects the localization of NR1I3 protein mutant form
6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein alternative form
6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of NR1I3 mRNA
6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein mutant form
6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime binds to NR1I3 protein
6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime binds to and results in increased activity of and results in increased localization of NR1I3 protein mutant form; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime binds to and results in increased activity of NR1I3 protein; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime binds to and results in increased activity of NR1I3 protein alternative form; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime binds to and results in increased activity of NR1I3 protein SNP; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime inhibits the reaction [androstan-3-ol binds to and results in decreased activity of NR1I3 protein alternative form]; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime inhibits the reaction [ethyl (5-(diethylglycyl)-10,11-dihydro-5H-dibenzo(b,f)azepin-3-yl)carbamate results in decreased activity of NR1I3 protein]; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime inhibits the reaction [Imidazoles binds to and results in decreased activity of NR1I3 protein alternative form]; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime inhibits the reaction [PK 11195 results in decreased activity of NR1I3 protein]; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime inhibits the reaction [T0901317 results in decreased activity of NR1I3 protein]; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [[NR1I3 protein binds to RXRA protein] which binds to ABCG2 promoter]; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [[NR1I3 protein co-treated with FOXO1 protein co-treated with HNF4A protein co-treated with NCOA1 protein] binds to CYP2C9 promoter]; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [MED1 protein binds to NR1I3 protein alternative form]; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [MED1 protein binds to NR1I3 protein]; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [NCOA1 protein binds to NR1I3 protein alternative form]; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [NCOA1 protein binds to NR1I3 protein]; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [NCOA3 protein binds to NR1I3 protein]; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [NR1I3 protein binds to NR0B1 protein]; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [NR1I3 protein modified form binds to NCOA1 protein]; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [NR1I3 protein results in increased expression of CYP2B10 mRNA]; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [SRC protein binds to NR1I3 protein]; [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime binds to and results in increased activity of NR1I3 protein] which results in increased expression of CYP2B6 mRNA; [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Anisomycin co-treated with NR1I3 protein] results in increased expression of CYP2B6 mRNA; [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with NR1I3 protein alternative form] results in increased expression of CYP2B6 mRNA; [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with NR1I3 protein mutant form] results in increased expression of CYP2B6 mRNA; [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with NR1I3 protein] results in increased expression of ABCG2 mRNA; [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [[NR1I3 protein binds to RXRA protein] which binds to ABCG2 promoter]] which results in increased expression of ABCG2 mRNA; [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein] which results in increased expression of CYP2B6 mRNA; [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein] which results in increased expression of DHCR24 mRNA; [Estradiol co-treated with Progesterone] inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein]; [Progesterone co-treated with Estradiol] inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [[NR1I3 protein co-treated with FOXO1 protein co-treated with HNF4A protein co-treated with NCOA1 protein] binds to CYP2C9 promoter]]; Acriflavine inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein]; allyl isothiocyanate inhibits the reaction [NR1I3 protein promotes the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]]; allyl isothiocyanate inhibits the reaction [NR1I3 protein promotes the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP3A4 mRNA]]; aroclor 1260 inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein alternative form]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime affects the localization of NR1I3 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein modified form]; Bortezomib inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein]; Clotrimazole inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime binds to and results in increased activity of NR1I3 protein mutant form]; Estradiol inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [[NR1I3 protein co-treated with FOXO1 protein co-treated with HNF4A protein co-treated with NCOA1 protein] binds to CYP2C9 promoter]]; Estradiol inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein]; Etoposide inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein]; Imidazoles inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein alternative form]; Meclizine inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein]; metoprine inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein]; NR1I3 mutant form inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of G6PC1 mRNA]; NR1I3 mutant form inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of SREBF1 mRNA]; NR1I3 mutant form inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]; NR1I3 mutant form inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2C9 mRNA]; NR1I3 mutant form inhibits the reaction [Estradiol inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of G6PC1 mRNA]]; NR1I3 mutant form inhibits the reaction [Estradiol inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of SREBF1 mRNA]]; NR1I3 mutant form inhibits the reaction [Estradiol inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]]; NR1I3 mutant form inhibits the reaction [Estradiol inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2C9 mRNA]]; NR1I3 mutant form inhibits the reaction [Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of G6PC1 mRNA]]; NR1I3 mutant form inhibits the reaction [Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of SREBF1 mRNA]]; NR1I3 mutant form inhibits the reaction [Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]]; NR1I3 mutant form inhibits the reaction [Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2C9 mRNA]]; NR1I3 protein promotes the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of CYP3A7 protein]; NR1I3 protein promotes the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]; NR1I3 protein promotes the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP3A4 mRNA]; Proflavine inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein]; Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [[NR1I3 protein co-treated with FOXO1 protein co-treated with HNF4A protein co-treated with NCOA1 protein] binds to CYP2C9 promoter]]; ST 1481 inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein]; T0901317 inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein mutant form]; Trifluridine inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein]
6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein alternative form; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein modified form; 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein mutant form
6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased activity of NR1I3 protein
6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime binds to NR1I3 protein; [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime binds to NR1I3 protein] which binds to CYP2C8 promoter
CTD PMID:15272053 PMID:15802384 PMID:15905360 PMID:15933212 PMID:15990349 More... NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions
increases expression
decreases expression
ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime inhibits the reaction [HNF4A protein binds to PCK1 promoter]; [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of PCK1 mRNA; [Progesterone co-treated with Estradiol] inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of PCK1 mRNA]; Estradiol inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime inhibits the reaction [HNF4A protein binds to PCK1 promoter]]; Estradiol inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of PCK1 mRNA]; Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime inhibits the reaction [HNF4A protein binds to PCK1 promoter]]; Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of PCK1 mRNA]; Progesterone promotes the reaction [Estradiol inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime inhibits the reaction [HNF4A protein binds to PCK1 promoter]]]
6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of PCK1 mRNA
CTD PMID:21768169 PMID:30611723 PMID:31312845 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 decreases expression ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of PDK4 mRNA CTD PMID:27551952 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
JBrowse link
G Pdss1 decaprenyl diphosphate synthase subunit 1 multiple interactions ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of PDSS1 mRNA CTD PMID:30611723 NCBI chr17:85,059,953...85,098,739
Ensembl chr17:85,060,106...85,098,730
JBrowse link
G Plin2 perilipin 2 multiple interactions ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of PLIN2 mRNA CTD PMID:30611723 NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
JBrowse link
G Pnpla3 patatin-like phospholipase domain containing 3 increases expression ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of PNPLA3 mRNA CTD PMID:27180240 NCBI chr 7:115,293,538...115,314,077
Ensembl chr 7:115,293,538...115,314,077
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of PPARA mRNA CTD PMID:30611723 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Rabggtb Rab geranylgeranyltransferase subunit beta multiple interactions ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of RABGGTB mRNA CTD PMID:30611723 NCBI chr 2:242,844,758...242,850,951
Ensembl chr 2:242,844,762...242,851,050
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [[NR1I3 protein binds to RXRA protein] which binds to ABCG2 promoter]; [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [[NR1I3 protein binds to RXRA protein] which binds to ABCG2 promoter]] which results in increased expression of ABCG2 mRNA CTD PMID:22093699 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression
multiple interactions
ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of SCD1 mRNA
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of SCD mRNA; [Progesterone co-treated with Estradiol] inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of SCD1 mRNA]; Estradiol inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of SCD1 mRNA]; Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of SCD1 mRNA]
CTD PMID:21768169 PMID:30611723 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Slc27a1 solute carrier family 27 member 1 multiple interactions ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of SLC27A1 mRNA CTD PMID:30611723 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
JBrowse link
G Slc27a2 solute carrier family 27 member 2 multiple interactions ISO [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of SLC27A2 mRNA CTD PMID:30611723 NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [SRC protein binds to NR1I3 protein] CTD PMID:24224465 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression
increases expression
multiple interactions
ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of SREBF1 mRNA
6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of SREBF1 mRNA
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of SREBF1 mRNA; [Progesterone co-treated with Estradiol] inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of SREBF1 mRNA]; Estradiol inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of SREBF1 mRNA]; NR1I3 mutant form inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of SREBF1 mRNA]; NR1I3 mutant form inhibits the reaction [Estradiol inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of SREBF1 mRNA]]; NR1I3 mutant form inhibits the reaction [Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of SREBF1 mRNA]]; Progesterone inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of SREBF1 mRNA]
CTD PMID:21768169 PMID:27180240 PMID:30611723 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Thrsp thyroid hormone responsive decreases expression ISO 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of THRSP mRNA CTD PMID:31312845 NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075
JBrowse link
6-bromoindirubin-3'-oxime term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
increases expression
ISO
EXP
6-bromoindirubin-3'-oxime results in increased expression of and results in increased activity of ABCB1 protein
6-bromoindirubin-3'-oxime results in increased expression of ABCB1 mRNA
6-bromoindirubin-3'-oxime results in increased expression of ABCB1A mRNA; 6-bromoindirubin-3'-oxime results in increased expression of ABCB1A protein
CTD PMID:18624906 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression ISO 6-bromoindirubin-3'-oxime results in increased expression of ABCC2 mRNA; 6-bromoindirubin-3'-oxime results in increased expression of ABCC2 protein CTD PMID:18624906 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases expression ISO 6-bromoindirubin-3'-oxime results in increased expression of ABCC4 mRNA; 6-bromoindirubin-3'-oxime results in increased expression of ABCC4 protein CTD PMID:18624906 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression ISO 6-bromoindirubin-3'-oxime results in increased expression of ABCG2 mRNA; 6-bromoindirubin-3'-oxime results in increased expression of ABCG2 protein CTD PMID:18624906 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO 6-bromoindirubin-3'-oxime binds to and results in increased activity of AHR protein CTD PMID:26259606 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 multiple interactions ISO [sorafenib co-treated with 6-bromoindirubin-3'-oxime] affects the localization of AIFM1 protein CTD PMID:17991738 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 multiple interactions ISO [trametinib co-treated with 6-bromoindirubin-3'-oxime] results in increased expression of ALDH1 protein; XAV939 inhibits the reaction [[trametinib co-treated with 6-bromoindirubin-3'-oxime] results in increased expression of ALDH1 protein] CTD PMID:37116855 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [trametinib co-treated with 6-bromoindirubin-3'-oxime] results in decreased expression of BAX protein CTD PMID:37116855 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [trametinib co-treated with 6-bromoindirubin-3'-oxime] results in increased expression of BCL2 protein CTD PMID:37116855 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Casp3 caspase 3 multiple interactions ISO [trametinib co-treated with 6-bromoindirubin-3'-oxime] results in decreased cleavage of CASP3 protein CTD PMID:37116855 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 multiple interactions ISO 6-bromoindirubin-3'-oxime promotes the reaction [Paraquat results in increased expression of CASP8 protein modified form] CTD PMID:28414160 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Ccnd1 cyclin D1 increases expression ISO
EXP
6-bromoindirubin-3'-oxime results in increased expression of CCND1 mRNA CTD PMID:18624906 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO 6-bromoindirubin-3'-oxime inhibits the reaction [Amiodarone results in increased expression of CDH1 protein] CTD PMID:26515726 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdx1 caudal type homeo box 1 multiple interactions ISO [Valproic Acid co-treated with 6-bromoindirubin-3'-oxime] results in increased expression of CDX1 mRNA CTD PMID:27693483 NCBI chr18:54,472,587...54,490,913
Ensembl chr18:54,473,444...54,490,814
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
decreases phosphorylation
increases expression
ISO [6-bromoindirubin-3'-oxime co-treated with DHFR mRNA] affects the expression of CTNNB1 protein; broussochalcone A inhibits the reaction [6-bromoindirubin-3'-oxime results in increased expression of CTNNB1 protein]; Methotrexate promotes the reaction [6-bromoindirubin-3'-oxime results in decreased phosphorylation of CTNNB1 protein]
[trametinib co-treated with 6-bromoindirubin-3'-oxime] results in decreased expression of CTNNB1 protein
CTD PMID:18624906 PMID:19727391 PMID:26259606 PMID:31163223 PMID:37116855 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression
multiple interactions
ISO 6-bromoindirubin-3'-oxime results in increased expression of CYP1A2 mRNA
6-bromoindirubin-3'-oxime results in increased expression of and results in increased activity of CYP1A2 protein
CTD PMID:26259606 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 multiple interactions ISO [Valproic Acid co-treated with 6-bromoindirubin-3'-oxime] affects the expression of CYP26A1 mRNA CTD PMID:27693483 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked multiple interactions ISO 6-bromoindirubin-3'-oxime promotes the reaction [Paraquat inhibits the reaction [TNFRSF10B protein binds to DDX3X protein]]; 6-bromoindirubin-3'-oxime promotes the reaction [Paraquat results in decreased expression of DDX3X protein modified form] CTD PMID:28414160 NCBI chr  X:9,479,532...9,493,169
Ensembl chr  X:9,479,532...9,493,168
JBrowse link
G Dhfr dihydrofolate reductase multiple interactions ISO [6-bromoindirubin-3'-oxime co-treated with DHFR mRNA] affects the expression of CTNNB1 protein CTD PMID:19727391 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein multiple interactions ISO 6-bromoindirubin-3'-oxime promotes the reaction [sorafenib affects the localization of DIABLO protein] CTD PMID:17991738 NCBI chr12:33,055,784...33,070,401
Ensembl chr12:33,055,263...33,070,387
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha multiple interactions ISO 6-bromoindirubin-3'-oxime promotes the reaction [Paraquat results in decreased expression of GSK3A protein modified form] CTD PMID:28414160 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases activity
increases phosphorylation
multiple interactions
ISO 6-bromoindirubin-3'-oxime results in decreased activity of GSK3B protein
6-bromoindirubin-3'-oxime results in increased phosphorylation of GSK3B protein
6-bromoindirubin-3'-oxime promotes the reaction [Paraquat inhibits the reaction [TNFRSF10B protein binds to GSK3B protein]]; 6-bromoindirubin-3'-oxime promotes the reaction [Paraquat results in decreased expression of GSK3B protein modified form]; Methotrexate promotes the reaction [6-bromoindirubin-3'-oxime results in increased phosphorylation of GSK3B protein]
[trametinib co-treated with 6-bromoindirubin-3'-oxime] affects the phosphorylation of GSK3B protein
CTD PMID:17991738 PMID:19727391 PMID:28414160 PMID:37116855 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Hoxa1 homeobox A1 multiple interactions ISO [Valproic Acid co-treated with 6-bromoindirubin-3'-oxime] affects the expression of HOXA1 mRNA CTD PMID:27693483 NCBI chr 4:81,255,814...81,258,587
Ensembl chr 4:81,255,883...81,258,504
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [6-bromoindirubin-3'-oxime co-treated with Methotrexate] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] CTD PMID:19727391 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Itga6 integrin subunit alpha 6 multiple interactions ISO [trametinib co-treated with 6-bromoindirubin-3'-oxime] results in increased expression of ITGA6 protein; XAV939 inhibits the reaction [[trametinib co-treated with 6-bromoindirubin-3'-oxime] results in increased expression of ITGA6 protein] CTD PMID:37116855 NCBI chr 3:56,604,512...56,689,428
Ensembl chr 3:56,617,268...56,689,428
JBrowse link
G Krt17 keratin 17 multiple interactions ISO [trametinib co-treated with 6-bromoindirubin-3'-oxime] results in increased expression of KRT17 protein; XAV939 inhibits the reaction [[trametinib co-treated with 6-bromoindirubin-3'-oxime] results in increased expression of KRT17 protein] CTD PMID:37116855 NCBI chr10:85,178,673...85,183,392
Ensembl chr10:85,178,675...85,183,392
JBrowse link
G Lgr5 leucine rich repeat containing G protein coupled receptor 5 increases expression ISO 6-bromoindirubin-3'-oxime results in increased expression of LGR5 mRNA CTD PMID:26259606 NCBI chr 7:51,087,059...51,221,882
Ensembl chr 7:51,088,239...51,222,446
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression ISO 6-bromoindirubin-3'-oxime results in decreased expression of MCL1 protein CTD PMID:17991738 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions ISO [trametinib co-treated with 6-bromoindirubin-3'-oxime] results in increased expression of MKI67 protein CTD PMID:37116855 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Nanog Nanog homeobox multiple interactions ISO [trametinib co-treated with 6-bromoindirubin-3'-oxime] results in increased expression of NANOG protein; XAV939 inhibits the reaction [[trametinib co-treated with 6-bromoindirubin-3'-oxime] results in increased expression of NANOG protein] CTD PMID:37116855 NCBI chr 4:155,943,737...155,951,116
Ensembl chr 4:155,943,737...155,951,116
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO 6-bromoindirubin-3'-oxime promotes the reaction [Paraquat results in increased expression of PARP1 protein modified form] CTD PMID:28414160 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 multiple interactions ISO 6-bromoindirubin-3'-oxime inhibits the reaction [sorafenib results in decreased expression of PMAIP1 protein] CTD PMID:17991738 NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Pou5f1 POU class 5 homeobox 1 multiple interactions ISO [Valproic Acid co-treated with 6-bromoindirubin-3'-oxime] results in decreased expression of POU5F1 mRNA
[trametinib co-treated with 6-bromoindirubin-3'-oxime] results in increased expression of POU5F1 protein; XAV939 inhibits the reaction [[trametinib co-treated with 6-bromoindirubin-3'-oxime] results in increased expression of POU5F1 protein]
CTD PMID:27693483 PMID:37116855 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
JBrowse link
G Sox2 SRY-box transcription factor 2 multiple interactions ISO [trametinib co-treated with 6-bromoindirubin-3'-oxime] results in increased expression of SOX2 protein; XAV939 inhibits the reaction [[trametinib co-treated with 6-bromoindirubin-3'-oxime] results in increased expression of SOX2 protein] CTD PMID:37116855 NCBI chr 2:117,536,929...117,539,340
Ensembl chr 2:117,536,929...117,539,338
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [6-bromoindirubin-3'-oxime co-treated with Methotrexate] inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] CTD PMID:19727391 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Wnt3 Wnt family member 3 multiple interactions ISO [Valproic Acid co-treated with 6-bromoindirubin-3'-oxime] results in decreased expression of WNT3 mRNA CTD PMID:27693483 NCBI chr10:88,680,198...88,724,170
Ensembl chr10:88,680,248...88,724,099
JBrowse link
acetaldehyde oxime term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions ISO acetaldehyde oxime inhibits the reaction [tabun results in decreased activity of ACHE protein] CTD PMID:22960624 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
aldicarb term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity EXP
ISO
Aldicarb results in decreased activity of ACHE protein CTD PMID:8134223 PMID:14644616 PMID:16256972 PMID:21251949 PMID:23962483 More... NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G App amyloid beta precursor protein decreases response to substance ISO APP protein modified form results in decreased susceptibility to Aldicarb CTD PMID:34902447 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions EXP Aldicarb results in decreased activity of [CHRNA4 protein binds to CHRNB4 protein] CTD PMID:14644616 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit multiple interactions EXP Aldicarb results in decreased activity of [CHRNA4 protein binds to CHRNB4 protein] CTD PMID:14644616 NCBI chr 8:55,417,583...55,437,027
Ensembl chr 8:55,418,313...55,437,027
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Aldicarb inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:9126867 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Il2 interleukin 2 decreases response to substance ISO Aldicarb results in decreased susceptibility to IL2 protein CTD PMID:8349949 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Map2 microtubule-associated protein 2 multiple interactions ISO Aldicarb promotes the reaction [[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with LDN 193189] results in increased expression of MAP2 mRNA] CTD PMID:32949729 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809
JBrowse link
G Nefh neurofilament heavy chain increases phosphorylation ISO Aldicarb results in increased phosphorylation of NEFH protein CTD PMID:16256972 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
JBrowse link
G Nrxn1 neurexin 1 multiple interactions ISO NRXN1 protein affects the reaction [NLG-1 results in increased susceptibility to Aldicarb]; NRXN1 protein affects the reaction [NRX-1 results in decreased susceptibility to Aldicarb] CTD PMID:23638761 NCBI chr 6:3,177,788...4,323,848
Ensembl chr 6:3,177,897...4,322,710
JBrowse link
G Pax6 paired box 6 multiple interactions ISO Aldicarb inhibits the reaction [[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with LDN 193189] results in increased expression of PAX6 mRNA] CTD PMID:32949729 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014
JBrowse link
G Pgr progesterone receptor multiple interactions ISO Aldicarb inhibits the reaction [Progesterone results in increased activity of PGR protein] CTD PMID:9126867 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Pon1 paraoxonase 1 multiple interactions ISO
EXP
[Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to Aldicarb; [Egtazic Acid results in decreased activity of PON1 protein] which results in increased susceptibility to Aldicarb CTD PMID:27132127 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link
G Vpreb1a V-set pre-B cell surrogate light chain 1A decreases expression ISO Aldicarb results in decreased expression of VPREB1 mRNA CTD PMID:25424538 NCBI chr11:84,126,969...84,127,846
Ensembl chr11:84,126,969...84,127,846
JBrowse link
cefdinir term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a6 solute carrier family 22 member 6 multiple interactions
increases uptake
ISO cefdinir inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid]
SLC22A6 protein results in increased uptake of cefdinir
CTD PMID:16098483 NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173
JBrowse link
G Slc22a8 solute carrier family 22 member 8 multiple interactions
increases uptake
ISO cefdinir inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]
SLC22A8 protein results in increased uptake of cefdinir
CTD PMID:16098483 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450
JBrowse link
diacetylmonoxime term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions ISO diacetylmonoxime inhibits the reaction [cyclohexyl methylphosphonofluoridate binds to and results in decreased activity of ACHE protein]; diacetylmonoxime inhibits the reaction [Paraoxon binds to and results in decreased activity of ACHE protein]; diacetylmonoxime inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; diacetylmonoxime inhibits the reaction [tabun results in decreased activity of ACHE protein]; diacetylmonoxime inhibits the reaction [VX binds to and results in decreased activity of ACHE protein] CTD PMID:22960624 PMID:22975155 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Acta2 actin alpha 2, smooth muscle decreases expression
affects localization
EXP
ISO
diacetylmonoxime results in decreased expression of ACTA2
diacetylmonoxime affects the localization of ACTA2 protein
CTD PMID:11591817 PMID:11868461 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Bche butyrylcholinesterase multiple interactions EXP diacetylmonoxime inhibits the reaction [Dichlorvos results in decreased activity of BCHE protein]; diacetylmonoxime inhibits the reaction [Isoflurophate results in decreased activity of BCHE protein] CTD PMID:1276991 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Casp3 caspase 3 multiple interactions ISO diacetylmonoxime inhibits the reaction [Demecolcine results in increased activity of CASP3 protein] CTD PMID:12530016 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression ISO diacetylmonoxime results in decreased expression of CDKN1A protein CTD PMID:15252113 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO diacetylmonoxime results in increased expression of CDKN1B protein CTD PMID:15252113 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Myod1 myogenic differentiation 1 decreases expression ISO diacetylmonoxime results in decreased expression of MYOD1 protein CTD PMID:15252113 NCBI chr 1:96,884,864...96,887,574
Ensembl chr 1:96,884,948...96,887,554
JBrowse link
G Myog myogenin decreases expression ISO diacetylmonoxime results in decreased expression of MYOG protein CTD PMID:15252113 NCBI chr13:45,745,455...45,748,044
Ensembl chr13:45,745,436...45,748,039
JBrowse link
G Tf transferrin decreases uptake ISO diacetylmonoxime results in decreased uptake of TF protein CTD PMID:16563724 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
JBrowse link
indirubin-3'-monoxime term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actb actin, beta affects expression ISO indirubin-3'-monoxime affects the expression of ACTB protein CTD PMID:18958680 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
affects binding
ISO AHR protein affects the susceptibility to [indirubin-3'-monoxime results in decreased expression of CD86 protein]; AHR protein affects the susceptibility to [indirubin-3'-monoxime results in decreased expression of ITGAX protein]
indirubin-3'-monoxime binds to and results in increased activity of AHR protein
indirubin-3'-monoxime binds to AHR protein
CTD PMID:15001395 PMID:21948866 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 multiple interactions
increases expression
ISO Lipopolysaccharides affects the susceptibility to [indirubin-3'-monoxime results in increased expression of ALDH1A1 protein] CTD PMID:21948866 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 decreases expression ISO indirubin-3'-monoxime results in decreased expression of ALDH1A2 protein CTD PMID:21948866 NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107
JBrowse link
G Aqp9 aquaporin 9 multiple interactions ISO indirubin-3'-monoxime promotes the reaction [tetraarsenic tetrasulfide results in increased expression of AQP9 mRNA]; indirubin-3'-monoxime promotes the reaction [tetraarsenic tetrasulfide results in increased expression of AQP9 protein] CTD PMID:18344322 NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395
JBrowse link
G Ar androgen receptor increases activity ISO indirubin-3'-monoxime analog results in increased activity of AR protein; indirubin-3'-monoxime results in increased activity of AR protein CTD PMID:21111724 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression ISO indirubin-3'-monoxime results in decreased expression of BAX mRNA CTD PMID:18958680 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions ISO [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BCL2L1 mRNA CTD PMID:18958680 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Casp8 caspase 8 multiple interactions ISO [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CASP8 mRNA CTD PMID:18958680 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Cat catalase multiple interactions ISO [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CAT mRNA CTD PMID:18958680 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 multiple interactions ISO [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CCL4 mRNA CTD PMID:18958680 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Cd40 CD40 molecule multiple interactions
decreases expression
ISO [Lipopolysaccharides co-treated with indirubin-3'-monoxime] results in decreased expression of CD40 protein; indirubin-3'-monoxime inhibits the reaction [Lipopolysaccharides results in increased expression of CD40 protein]
indirubin-3'-monoxime results in decreased expression of CD40 protein
CTD PMID:21948866 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cd80 Cd80 molecule increases expression
multiple interactions
ISO indirubin-3'-monoxime results in increased expression of CD80 protein
[Lipopolysaccharides co-treated with indirubin-3'-monoxime] results in increased expression of CD80 protein; indirubin-3'-monoxime promotes the reaction [Lipopolysaccharides results in increased expression of CD80 protein]
CTD PMID:21948866 NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030
JBrowse link
G Cd86 CD86 molecule multiple interactions
decreases expression
ISO [Lipopolysaccharides co-treated with indirubin-3'-monoxime] results in decreased expression of CD86 protein; AHR protein affects the susceptibility to [indirubin-3'-monoxime results in decreased expression of CD86 protein]; indirubin-3'-monoxime inhibits the reaction [Lipopolysaccharides results in increased expression of CD86 protein] CTD PMID:21948866 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases activity ISO indirubin-3'-monoxime results in decreased activity of CDK2 protein CTD PMID:12534346 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CDKN1A mRNA CTD PMID:18958680 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO
EXP
[indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of CYP1A1 mRNA; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP1A1 mRNA; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP1A1 protein
indirubin-3'-monoxime results in increased expression of CYP1A1 mRNA
indirubin-3'-monoxime results in increased expression of CYP1A1 protein
CTD PMID:15001395 PMID:18958680 PMID:21948866 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Ephx2 epoxide hydrolase 2 decreases expression ISO indirubin-3'-monoxime results in decreased expression of EPHX2 mRNA CTD PMID:18958680 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression ISO indirubin-3'-monoxime results in decreased expression of GPX1 mRNA CTD PMID:18958680 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases activity ISO indirubin-3'-monoxime results in decreased activity of GSK3B protein CTD PMID:12534346 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsr glutathione-disulfide reductase increases expression ISO indirubin-3'-monoxime results in increased expression of GSR mRNA CTD PMID:18958680 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HMOX1 mRNA CTD PMID:18958680 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 multiple interactions ISO [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in decreased expression of HSPA2 mRNA; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HSPA2 mRNA CTD PMID:18958680 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
JBrowse link
G Hspa6l-ps1 heat shock protein family A (Hsp70) member 6 like, pseudogene 1 multiple interactions ISO [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HSPA6 mRNA CTD PMID:18958680 NCBI chr13:83,273,176...83,274,317 JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 multiple interactions
increases expression
ISO [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HSPA9 mRNA
indirubin-3'-monoxime results in increased expression of HSPA9 mRNA
CTD PMID:18958680 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
decreases expression
ISO [Lipopolysaccharides co-treated with indirubin-3'-monoxime] results in decreased expression of ICAM1 protein; indirubin-3'-monoxime inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]
indirubin-3'-monoxime results in decreased expression of ICAM1 protein
CTD PMID:21948866 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 increases expression
multiple interactions
ISO indirubin-3'-monoxime results in increased expression of IDO1 protein
Lipopolysaccharides affects the susceptibility to [indirubin-3'-monoxime results in increased expression of IDO1 protein]
CTD PMID:21948866 NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 increases expression
multiple interactions
ISO indirubin-3'-monoxime results in increased expression of IDO2 protein
Lipopolysaccharides affects the susceptibility to [indirubin-3'-monoxime results in increased expression of IDO2 protein]
CTD PMID:21948866 NCBI chr16:67,459,158...67,498,052
Ensembl chr16:67,459,190...67,496,324
JBrowse link
G Ifng interferon gamma decreases secretion ISO indirubin-3'-monoxime results in decreased secretion of IFNG protein CTD PMID:21948866 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il10 interleukin 10 multiple interactions
decreases secretion
ISO [Lipopolysaccharides co-treated with indirubin-3'-monoxime] results in increased secretion of IL10 protein; indirubin-3'-monoxime promotes the reaction [Lipopolysaccharides results in increased secretion of IL10 protein]
indirubin-3'-monoxime results in decreased secretion of IL10 protein
CTD PMID:21948866 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [Lipopolysaccharides co-treated with indirubin-3'-monoxime] results in decreased secretion of IL1B protein; indirubin-3'-monoxime inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] CTD PMID:21948866 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2 interleukin 2 increases secretion ISO indirubin-3'-monoxime results in increased secretion of IL2 protein CTD PMID:21948866 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il27 interleukin 27 decreases expression
multiple interactions
ISO indirubin-3'-monoxime results in decreased expression of IL27 protein
Lipopolysaccharides affects the susceptibility to [indirubin-3'-monoxime results in decreased expression of IL27 protein]
CTD PMID:21948866 NCBI chr 1:181,173,108...181,178,720
Ensembl chr 1:181,173,372...181,178,582
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Lipopolysaccharides co-treated with indirubin-3'-monoxime] results in decreased expression of IL6 protein; [Lipopolysaccharides co-treated with indirubin-3'-monoxime] results in decreased secretion of IL6 protein; indirubin-3'-monoxime inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] CTD PMID:21948866 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Itgax integrin subunit alpha X multiple interactions
decreases expression
ISO AHR protein affects the susceptibility to [indirubin-3'-monoxime results in decreased expression of ITGAX protein]; indirubin-3'-monoxime inhibits the reaction [Lipopolysaccharides results in increased expression of ITGAX protein] CTD PMID:21948866 NCBI chr 1:182,709,653...182,740,709
Ensembl chr 1:182,719,609...182,740,698
JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 increases expression ISO indirubin-3'-monoxime analog results in increased expression of KLK3 mRNA; indirubin-3'-monoxime results in increased expression of KLK3 mRNA CTD PMID:21111724 NCBI chr 1:94,402,993...94,407,052
Ensembl chr 1:94,402,993...94,407,052
JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase decreases activity ISO indirubin-3'-monoxime results in decreased activity of LCK protein CTD PMID:12534346 NCBI chr 5:141,888,318...141,916,945
Ensembl chr 5:141,888,326...141,903,794
JBrowse link
G Mt2A metallothionein 2A multiple interactions ISO [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MT2A mRNA CTD PMID:18958680 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in decreased expression of NFKBIA mRNA CTD PMID:18958680 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 mRNA; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 protein CTD PMID:18958680 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rad23a RAD23 homolog A, nucleotide excision repair protein decreases expression ISO indirubin-3'-monoxime results in decreased expression of RAD23A mRNA CTD PMID:18958680 NCBI chr19:23,313,563...23,320,702
Ensembl chr19:23,314,797...23,320,695
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
decreases activity
ISO [Lipopolysaccharides co-treated with indirubin-3'-monoxime] results in increased activity of RELA protein
indirubin-3'-monoxime results in decreased activity of RELA protein
CTD PMID:21948866 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SERPINE1 mRNA CTD PMID:18958680 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 decreases activity ISO indirubin-3'-monoxime results in decreased activity of SGK1 protein CTD PMID:12534346 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of SOD2 mRNA CTD PMID:18958680 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Tgfb2 transforming growth factor, beta 2 increases expression
multiple interactions
ISO indirubin-3'-monoxime results in increased expression of TGFB2 protein
Lipopolysaccharides affects the susceptibility to [indirubin-3'-monoxime results in increased expression of TGFB2 protein]
CTD PMID:21948866 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Tgfb3 transforming growth factor, beta 3 increases expression
multiple interactions
ISO indirubin-3'-monoxime results in increased expression of TGFB3 protein
Lipopolysaccharides affects the susceptibility to [indirubin-3'-monoxime results in increased expression of TGFB3 protein]
CTD PMID:21948866 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [Lipopolysaccharides co-treated with indirubin-3'-monoxime] results in decreased secretion of TNF protein; indirubin-3'-monoxime inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] CTD PMID:21948866 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Ung uracil-DNA glycosylase increases expression ISO indirubin-3'-monoxime results in increased expression of UNG mRNA CTD PMID:18958680 NCBI chr12:42,485,276...42,494,217
Ensembl chr12:42,485,276...42,494,206
JBrowse link
N(4)-hydroxycytidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aars1 alanyl-tRNA synthetase 1 increases expression ISO N(4)-hydroxycytidine results in increased expression of AARS mRNA CTD PMID:37748715 NCBI chr19:38,999,130...39,021,152
Ensembl chr19:38,999,163...39,021,147
JBrowse link
G Abcf3 ATP binding cassette subfamily F member 3 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ABCF3 mRNA CTD PMID:37748715 NCBI chr11:80,340,476...80,352,211
Ensembl chr11:80,339,977...80,352,211
JBrowse link
G Ace angiotensin I converting enzyme decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ACE mRNA CTD PMID:37748715 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Adap2 ArfGAP with dual PH domains 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ADAP2 mRNA CTD PMID:37748715 NCBI chr10:65,138,006...65,166,147
Ensembl chr10:65,138,020...65,165,604
JBrowse link
G Adgra2 adhesion G protein-coupled receptor A2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ADGRA2 mRNA CTD PMID:37748715 NCBI chr16:64,932,964...64,971,433
Ensembl chr16:64,933,315...64,971,483
JBrowse link
G Adgra3 adhesion G protein-coupled receptor A3 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ADGRA3 mRNA CTD PMID:37748715 NCBI chr14:60,874,719...60,976,341
Ensembl chr14:60,874,715...60,976,332
JBrowse link
G Adgrg1 adhesion G protein-coupled receptor G1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ADGRG1 mRNA CTD PMID:37748715 NCBI chr19:10,003,963...10,041,122
Ensembl chr19:10,003,975...10,041,108
JBrowse link
G Akirin1 akirin 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of AKIRIN1 mRNA CTD PMID:37748715 NCBI chr 5:135,989,378...136,004,782
Ensembl chr 5:135,989,465...136,004,762
JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 increases expression ISO N(4)-hydroxycytidine results in increased expression of ALDH18A1 mRNA CTD PMID:37748715 NCBI chr 1:239,375,657...239,407,956
Ensembl chr 1:239,375,669...239,407,890
JBrowse link
G Alkbh5 alkB homolog 5, RNA demethylase decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ALKBH5 mRNA CTD PMID:37748715 NCBI chr10:45,344,888...45,366,331
Ensembl chr10:45,343,395...45,366,331
JBrowse link
G Apbb1ip amyloid beta precursor protein binding family B member 1 interacting protein decreases expression ISO N(4)-hydroxycytidine results in decreased expression of APBB1IP mRNA CTD PMID:37748715 NCBI chr17:84,941,404...85,033,020
Ensembl chr17:84,982,243...85,033,010
JBrowse link
G Apela apelin receptor early endogenous ligand decreases expression ISO N(4)-hydroxycytidine results in decreased expression of APELA mRNA CTD PMID:37748715 NCBI chr16:24,694,356...24,703,466
Ensembl chr16:24,694,324...24,703,465
JBrowse link
G Arih2 ariadne RBR E3 ubiquitin protein ligase 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ARIH2 mRNA CTD PMID:37748715 NCBI chr 8:109,296,738...109,355,909
Ensembl chr 8:109,296,738...109,355,852
JBrowse link
G Arl14ep ADP-ribosylation factor like GTPase 14 effector protein decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ARL14EP mRNA CTD PMID:37748715 NCBI chr 3:93,441,952...93,454,282
Ensembl chr 3:93,443,183...93,454,155
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ARNT mRNA CTD PMID:37748715 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
JBrowse link
G Arrdc4 arrestin domain containing 4 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ARRDC4 mRNA CTD PMID:37748715 NCBI chr 1:122,369,355...122,383,351
Ensembl chr 1:122,369,360...122,383,290
JBrowse link
G Asb8 ankyrin repeat and SOCS box-containing 8 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ASB8 mRNA CTD PMID:37748715 NCBI chr 7:129,261,397...129,297,492
Ensembl chr 7:129,261,397...129,297,485
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression
multiple interactions
ISO N(4)-hydroxycytidine results in increased expression of ASNS mRNA
4-nitrobenzylthioinosine inhibits the reaction [N(4)-hydroxycytidine results in increased expression of ASNS mRNA]
CTD PMID:37748715 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Ate1 arginyltransferase 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ATE1 mRNA CTD PMID:37748715 NCBI chr 1:184,961,548...185,081,112
Ensembl chr 1:184,963,562...185,080,908
JBrowse link
G Atf2 activating transcription factor 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ATF2 mRNA CTD PMID:37748715 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO N(4)-hydroxycytidine results in increased expression of ATF3 mRNA CTD PMID:37748715 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atf4 activating transcription factor 4 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ATF4 mRNA CTD PMID:37748715 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atf5 activating transcription factor 5 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ATF5 mRNA CTD PMID:37748715 NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707
JBrowse link
G Atf6 activating transcription factor 6 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ATF6 mRNA CTD PMID:37748715 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Aup1 AUP1, lipid droplet regulating VLDL assembly factor decreases expression ISO N(4)-hydroxycytidine results in decreased expression of AUP1 mRNA CTD PMID:37748715 NCBI chr 4:115,560,274...115,563,346
Ensembl chr 4:115,560,261...115,563,346
JBrowse link
G Avil advillin decreases expression ISO N(4)-hydroxycytidine results in decreased expression of AVIL mRNA CTD PMID:37748715 NCBI chr 7:62,825,459...62,844,103
Ensembl chr 7:62,826,025...62,844,071
JBrowse link
G B3galnt1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) decreases expression ISO N(4)-hydroxycytidine results in decreased expression of B3GALNT1 mRNA CTD PMID:37748715 NCBI chr 2:153,847,297...153,877,371
Ensembl chr 2:153,846,474...153,877,332
JBrowse link
G Bbx BBX high mobility group box domain containing decreases expression ISO N(4)-hydroxycytidine results in decreased expression of BBX mRNA CTD PMID:37748715 NCBI chr11:50,381,249...50,628,934
Ensembl chr11:50,381,247...50,623,251
JBrowse link
G Bglap bone gamma-carboxyglutamate protein decreases expression ISO N(4)-hydroxycytidine results in decreased expression of BGLAP mRNA CTD PMID:37748715 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Brms1l BRMS1 like transcriptional repressor decreases expression ISO N(4)-hydroxycytidine results in decreased expression of BRMS1L mRNA CTD PMID:37748715 NCBI chr 6:73,266,673...73,300,630
Ensembl chr 6:73,266,691...73,300,631
JBrowse link
G Calml4 calmodulin-like 4 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of CALML4 mRNA CTD PMID:37748715 NCBI chr 8:63,323,426...63,335,234
Ensembl chr 8:63,323,351...63,335,234
JBrowse link
G Carhsp1 calcium regulated heat stable protein 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of CARHSP1 mRNA CTD PMID:37748715 NCBI chr10:6,946,036...6,960,556
Ensembl chr10:6,946,959...7,020,019
JBrowse link
G Carmil1 capping protein regulator and myosin 1 linker 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of CARMIL1 mRNA CTD PMID:37748715 NCBI chr17:40,807,921...41,088,326
Ensembl chr17:40,808,389...41,088,326
JBrowse link
G Cars1 cysteinyl-tRNA synthetase 1 increases expression ISO N(4)-hydroxycytidine results in increased expression of CARS mRNA CTD PMID:37748715 NCBI chr 1:198,753,689...198,796,016
Ensembl chr 1:198,753,691...198,795,941
JBrowse link
G Cbx7 chromobox 7 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of CBX7 mRNA CTD PMID:37748715 NCBI chr 7:111,460,656...111,479,231
Ensembl chr 7:111,460,656...111,477,973
JBrowse link
G Ccnb2 cyclin B2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of CCNB2 mRNA CTD PMID:37748715 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Cd68 Cd68 molecule decreases expression ISO N(4)-hydroxycytidine results in decreased expression of CD68 mRNA CTD PMID:37748715 NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
JBrowse link
G Cdca3 cell division cycle associated 3 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of CDCA3 mRNA CTD PMID:37748715 NCBI chr 4:157,634,775...157,638,799
Ensembl chr 4:157,634,928...157,638,799
JBrowse link
G Cebpg CCAAT/enhancer binding protein gamma decreases expression ISO N(4)-hydroxycytidine results in decreased expression of CEBPG mRNA CTD PMID:37748715 NCBI chr 1:87,683,060...87,692,772
Ensembl chr 1:87,684,019...87,694,569
JBrowse link
G Cep170 centrosomal protein 170 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of CEP170 mRNA CTD PMID:37748715 NCBI chr13:88,669,672...88,754,011
Ensembl chr13:88,670,358...88,732,226
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 multiple interactions
increases expression
ISO 4-nitrobenzylthioinosine inhibits the reaction [N(4)-hydroxycytidine results in increased expression of CHAC1 mRNA] CTD PMID:37748715 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
JBrowse link
G Coa7 cytochrome c oxidase assembly factor 7 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of COA7 mRNA CTD PMID:37748715 NCBI chr 5:123,069,356...123,080,942
Ensembl chr 5:123,069,371...123,080,199
JBrowse link
G Commd5 COMM domain containing 5 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of COMMD5 mRNA CTD PMID:37748715 NCBI chr 7:108,621,766...108,623,616
Ensembl chr 7:108,598,673...108,624,764
JBrowse link
G Cox6a2 cytochrome c oxidase subunit 6A2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of COX6A2 mRNA CTD PMID:37748715 NCBI chr 1:182,788,528...182,790,746
Ensembl chr 1:182,788,528...182,789,274
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A decreases expression ISO N(4)-hydroxycytidine results in decreased expression of CPT1A mRNA CTD PMID:37748715 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Cryzl1 crystallin zeta like 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of CRYZL1 mRNA CTD PMID:37748715 NCBI chr11:30,933,140...30,977,936
Ensembl chr11:30,933,144...30,977,867
JBrowse link
G Csf3r colony stimulating factor 3 receptor decreases expression ISO N(4)-hydroxycytidine results in decreased expression of CSF3R mRNA CTD PMID:37748715 NCBI chr 5:138,298,605...138,318,224
Ensembl chr 5:138,301,506...138,317,881
JBrowse link
G Ctps2 CTP synthase 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of CTPS2 mRNA CTD PMID:37748715 NCBI chr  X:31,645,873...31,786,733
Ensembl chr  X:31,645,873...31,786,733
JBrowse link
G Cyb5b cytochrome b5 type B multiple interactions ISO [CYB5B protein co-treated with CYB5R3 protein co-treated with MTARC1 protein] results in increased reduction of N(4)-hydroxycytidine; [CYB5B protein co-treated with CYB5R3 protein co-treated with MTARC2 protein] results in increased reduction of N(4)-hydroxycytidine CTD PMID:22924387 NCBI chr19:35,062,871...35,096,741
Ensembl chr19:35,062,813...35,098,249
JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 multiple interactions ISO [CYB5B protein co-treated with CYB5R3 protein co-treated with MTARC1 protein] results in increased reduction of N(4)-hydroxycytidine; [CYB5B protein co-treated with CYB5R3 protein co-treated with MTARC2 protein] results in increased reduction of N(4)-hydroxycytidine CTD PMID:22924387 NCBI chr 7:114,306,686...114,324,247
Ensembl chr 7:114,306,685...114,324,298
JBrowse link
G Dcaf15 DDB1 and CUL4 associated factor 15 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of DCAF15 mRNA CTD PMID:37748715 NCBI chr19:24,053,925...24,061,277
Ensembl chr19:24,053,925...24,061,277
JBrowse link
G Ddhd2 DDHD domain containing 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of DDHD2 mRNA CTD PMID:37748715 NCBI chr16:66,319,469...66,349,025
Ensembl chr16:66,319,466...66,349,023
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
ISO 4-nitrobenzylthioinosine inhibits the reaction [N(4)-hydroxycytidine results in increased expression of DDIT3 mRNA] CTD PMID:37748715 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO N(4)-hydroxycytidine results in increased expression of DDIT4 mRNA CTD PMID:37748715 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Ddx19b DEAD-box helicase 19B decreases expression ISO N(4)-hydroxycytidine results in decreased expression of DDX19B mRNA CTD PMID:37748715 NCBI chr19:38,968,215...38,998,907
Ensembl chr19:38,968,215...38,997,259
JBrowse link
G Ddx4 DEAD-box helicase 4 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of DDX4 mRNA CTD PMID:37748715 NCBI chr 2:44,227,946...44,282,867
Ensembl chr 2:44,227,946...44,282,723
JBrowse link
G Def8 differentially expressed in FDCP 8 homolog decreases expression ISO N(4)-hydroxycytidine results in decreased expression of DEF8 mRNA CTD PMID:37748715 NCBI chr19:51,474,783...51,495,638
Ensembl chr19:51,474,878...51,495,638
JBrowse link
G Dnajc5g DnaJ heat shock protein family (Hsp40) member C5 gamma decreases expression ISO N(4)-hydroxycytidine results in decreased expression of DNAJC5G mRNA CTD PMID:37748715 NCBI chr 6:25,260,087...25,264,251
Ensembl chr 6:25,260,088...25,264,152
JBrowse link
G Dnmt1 DNA methyltransferase 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of DNMT1 mRNA CTD PMID:37748715 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Dusp11 dual specificity phosphatase 11 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of DUSP11 mRNA CTD PMID:37748715 NCBI chr 4:118,367,673...118,385,183
Ensembl chr 4:118,368,053...118,385,181
JBrowse link
G Dusp16 dual specificity phosphatase 16 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of DUSP16 mRNA CTD PMID:37748715 NCBI chr 4:167,546,780...167,630,173
Ensembl chr 4:167,548,155...167,629,980
JBrowse link
G Dusp19 dual specificity phosphatase 19 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of DUSP19 mRNA CTD PMID:37748715 NCBI chr 3:65,538,424...65,554,465
Ensembl chr 3:65,538,420...65,553,534
JBrowse link
G Dynll1 dynein light chain LC8-type 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of DYNLL1 mRNA CTD PMID:37748715 NCBI chr12:41,312,365...41,316,157
Ensembl chr12:41,312,367...41,314,741
JBrowse link
G Dyrk4 dual specificity tyrosine phosphorylation regulated kinase 4 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of DYRK4 mRNA CTD PMID:37748715 NCBI chr 4:159,715,658...159,757,660
Ensembl chr 4:159,715,417...159,757,627
JBrowse link
G E2f8 E2F transcription factor 8 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of E2F8 mRNA CTD PMID:37748715 NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of EIF4EBP1 mRNA CTD PMID:37748715 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Elf1 E74 like ETS transcription factor 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ELF1 mRNA CTD PMID:37748715 NCBI chr15:54,890,644...54,986,721
Ensembl chr15:54,865,616...54,986,699
JBrowse link
G Emc9 ER membrane protein complex subunit 9 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of EMC9 mRNA CTD PMID:37748715 NCBI chr15:29,071,881...29,076,098
Ensembl chr15:29,071,883...29,076,098
JBrowse link
G Enpep glutamyl aminopeptidase decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ENPEP mRNA CTD PMID:37748715 NCBI chr 2:217,781,985...217,851,947
Ensembl chr 2:217,782,005...217,851,947
JBrowse link
G Epb41l5 erythrocyte membrane protein band 4.1 like 5 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of EPB41L5 mRNA CTD PMID:37748715 NCBI chr13:30,670,792...30,770,213
Ensembl chr13:30,669,764...30,768,360
JBrowse link
G Exosc6 exosome component 6 increases expression ISO N(4)-hydroxycytidine results in increased expression of EXOSC6 mRNA CTD PMID:37748715 NCBI chr19:39,022,171...39,023,585
Ensembl chr19:39,022,183...39,023,515
JBrowse link
G Fam98a family with sequence similarity 98, member A decreases expression ISO N(4)-hydroxycytidine results in decreased expression of FAM98A mRNA CTD PMID:37748715 NCBI chr 6:19,874,082...19,888,744
Ensembl chr 6:19,874,071...19,888,742
JBrowse link
G Fanca FA complementation group A decreases expression ISO N(4)-hydroxycytidine results in decreased expression of FANCA mRNA CTD PMID:37748715 NCBI chr19:51,304,126...51,362,586
Ensembl chr19:51,304,021...51,362,527
JBrowse link
G Fbxl12 F-box and leucine-rich repeat protein 12 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of FBXL12 mRNA CTD PMID:37748715 NCBI chr 8:19,175,864...19,183,373
Ensembl chr 8:19,160,352...19,183,607
JBrowse link
G Fbxo5 F-box protein 5 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of FBXO5 mRNA CTD PMID:37748715 NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437
JBrowse link
G Fetub fetuin B decreases expression ISO N(4)-hydroxycytidine results in decreased expression of FETUB mRNA CTD PMID:37748715 NCBI chr11:78,082,158...78,093,022
Ensembl chr11:78,082,156...78,095,135
JBrowse link
G Fhip2b FHF complex subunit HOOK interacting protein 2B decreases expression ISO N(4)-hydroxycytidine results in decreased expression of FHIP2B mRNA CTD PMID:37748715 NCBI chr15:45,656,641...45,674,603
Ensembl chr15:45,656,647...45,674,105
JBrowse link
G Foxk2 forkhead box K2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of FOXK2 mRNA CTD PMID:37748715 NCBI chr10:106,542,643...106,592,569
Ensembl chr10:106,542,566...106,592,563
JBrowse link
G Fzd4 frizzled class receptor 4 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of FZD4 mRNA CTD PMID:37748715 NCBI chr 1:143,279,934...143,288,799
Ensembl chr 1:143,280,065...143,285,724
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha decreases expression ISO N(4)-hydroxycytidine results in decreased expression of GADD45A mRNA CTD PMID:37748715 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gars1 glycyl-tRNA synthetase 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of GARS mRNA CTD PMID:37748715 NCBI chr 4:84,171,596...84,212,609
Ensembl chr 4:84,171,596...84,212,609
JBrowse link
G Gas2 growth arrest-specific 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of GAS2 mRNA CTD PMID:37748715 NCBI chr 1:101,452,361...101,582,619
Ensembl chr 1:101,482,591...101,582,619
JBrowse link
G Gdf15 growth differentiation factor 15 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of GDF15 mRNA CTD PMID:37748715 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gid4 GID complex subunit 4 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of GID4 mRNA CTD PMID:37748715 NCBI chr10:45,221,556...45,247,627
Ensembl chr10:45,245,754...45,247,621
Ensembl chr10:45,245,754...45,247,621
JBrowse link
G Glb1 galactosidase, beta 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of GLB1 mRNA CTD PMID:37748715 NCBI chr 8:114,085,508...114,158,127
Ensembl chr 8:114,085,508...114,158,127
JBrowse link
G Gpt2 glutamic--pyruvic transaminase 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of GPT2 mRNA CTD PMID:37748715 NCBI chr19:21,526,800...21,561,314
Ensembl chr19:21,517,621...21,560,610
JBrowse link
G Grb10 growth factor receptor bound protein 10 increases expression ISO N(4)-hydroxycytidine results in increased expression of GRB10 mRNA CTD PMID:37748715 NCBI chr14:86,495,051...86,602,800
Ensembl chr14:86,495,054...86,602,806
JBrowse link
G Grcc10 gene rich cluster, C10 gene decreases expression ISO N(4)-hydroxycytidine results in decreased expression of GRCC10 mRNA CTD PMID:37748715 NCBI chr 4:157,551,276...157,552,924 JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha decreases expression ISO N(4)-hydroxycytidine results in decreased expression of HADHA mRNA CTD PMID:37748715 NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta decreases expression ISO N(4)-hydroxycytidine results in decreased expression of HADHB mRNA CTD PMID:37748715 NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869
JBrowse link
G Hax1 HCLS1 associated protein X-1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of HAX1 mRNA CTD PMID:37748715 NCBI chr 2:175,434,242...175,437,926
Ensembl chr 2:175,434,238...175,437,714
JBrowse link
G Helz helicase with zinc finger decreases expression ISO N(4)-hydroxycytidine results in decreased expression of HELZ mRNA CTD PMID:37748715 NCBI chr10:92,479,403...92,645,234
Ensembl chr10:92,501,518...92,638,383
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression
multiple interactions
ISO N(4)-hydroxycytidine results in increased expression of HERPUD1 mRNA
4-nitrobenzylthioinosine inhibits the reaction [N(4)-hydroxycytidine results in increased expression of HERPUD1 mRNA]
CTD PMID:37748715 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
JBrowse link
G Herpud2 HERPUD family member 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of HERPUD2 mRNA CTD PMID:37748715 NCBI chr 8:23,573,374...23,618,380
Ensembl chr 8:23,573,379...23,617,874
JBrowse link
G Hexa hexosaminidase subunit alpha decreases expression ISO N(4)-hydroxycytidine results in decreased expression of HEXA mRNA CTD PMID:37748715 NCBI chr 8:59,936,526...59,961,654
Ensembl chr 8:59,936,660...59,962,013
JBrowse link
G Hexim1 HEXIM P-TEFb complex subunit 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of HEXIM1 mRNA CTD PMID:37748715 NCBI chr10:88,062,808...88,064,920
Ensembl chr10:88,062,803...88,066,189
JBrowse link
G Hmox1 heme oxygenase 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of HMOX1 mRNA CTD PMID:37748715 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Iars1 isoleucyl-tRNA synthetase 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of IARS mRNA CTD PMID:37748715 NCBI chr17:14,940,919...14,987,277
Ensembl chr17:14,940,924...14,987,237
JBrowse link
G Id2 inhibitor of DNA binding 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ID2 mRNA CTD PMID:37748715 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
JBrowse link
G Inip INTS3 and NABP interacting protein decreases expression ISO N(4)-hydroxycytidine results in decreased expression of INIP mRNA CTD PMID:37748715 NCBI chr 5:74,648,392...74,662,628
Ensembl chr 5:74,648,392...74,662,628
JBrowse link
G Irak1bp1 interleukin-1 receptor-associated kinase 1 binding protein 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of IRAK1BP1 mRNA CTD PMID:37748715 NCBI chr 8:83,731,512...83,748,289
Ensembl chr 8:83,731,507...83,748,289
JBrowse link
G Irf2bp2 interferon regulatory factor 2 binding protein 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of IRF2BP2 mRNA CTD PMID:37748715 NCBI chr19:54,559,417...54,565,096
Ensembl chr19:54,560,128...54,566,642
JBrowse link
G Jam3 junctional adhesion molecule 3 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of JAM3 mRNA CTD PMID:37748715 NCBI chr 8:25,508,461...25,569,306
Ensembl chr 8:25,507,057...25,569,355
JBrowse link
G Jdp2 Jun dimerization protein 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of JDP2 mRNA CTD PMID:37748715 NCBI chr 6:105,261,619...105,302,386
Ensembl chr 6:105,261,373...105,301,485
JBrowse link
G Lgals1 galectin 1 multiple interactions
decreases expression
ISO 4-nitrobenzylthioinosine inhibits the reaction [N(4)-hydroxycytidine results in decreased expression of LGALS1 mRNA] CTD PMID:37748715 NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345
JBrowse link
G Lig1 DNA ligase 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of LIG1 mRNA CTD PMID:37748715 NCBI chr 1:74,165,688...74,204,400
Ensembl chr 1:74,165,842...74,204,413
JBrowse link
G Lrfn1 leucine rich repeat and fibronectin type III domain containing 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of LRFN1 mRNA CTD PMID:37748715 NCBI chr 1:83,742,442...83,761,450
Ensembl chr 1:83,682,964...83,761,449
JBrowse link
G Lyrm7 LYR motif containing 7 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of LYRM7 mRNA CTD PMID:37748715 NCBI chr10:38,964,299...38,983,628
Ensembl chr10:38,964,311...38,983,601
JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of MAP2K5 mRNA CTD PMID:37748715 NCBI chr 8:63,625,220...63,852,090
Ensembl chr 8:63,625,221...63,851,983
JBrowse link
G Mapre3 microtubule-associated protein, RP/EB family, member 3 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of MAPRE3 mRNA CTD PMID:37748715 NCBI chr 6:25,513,800...25,558,876
Ensembl chr 6:25,513,800...25,558,881
JBrowse link
G Mcam melanoma cell adhesion molecule decreases expression ISO N(4)-hydroxycytidine results in decreased expression of MCAM mRNA CTD PMID:37748715 NCBI chr 8:44,479,391...44,487,575
Ensembl chr 8:44,479,376...44,487,571
JBrowse link
G Mdh1 malate dehydrogenase 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of MDH1 mRNA CTD PMID:37748715 NCBI chr14:95,630,625...95,645,920
Ensembl chr14:95,630,306...95,645,925
JBrowse link
G Midn midnolin decreases expression ISO N(4)-hydroxycytidine results in decreased expression of MIDN mRNA CTD PMID:37748715 NCBI chr 7:9,548,100...9,559,605
Ensembl chr 7:9,549,650...9,559,752
JBrowse link
G Mknk1 MAPK interacting serine/threonine kinase 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of MKNK1 mRNA CTD PMID:37748715 NCBI chr 5:129,318,128...129,357,641
Ensembl chr 5:129,318,170...129,357,639
JBrowse link
G Mob4 MOB family member 4, phocein decreases expression ISO N(4)-hydroxycytidine results in decreased expression of MOB4 mRNA CTD PMID:37748715 NCBI chr 9:56,617,374...56,641,336
Ensembl chr 9:56,617,368...56,641,329
JBrowse link
G Mrps12 mitochondrial ribosomal protein S12 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of MRPS12 mRNA CTD PMID:37748715 NCBI chr 1:84,025,896...84,028,896
Ensembl chr 1:84,025,899...84,028,780
JBrowse link
G Mrps27 mitochondrial ribosomal protein S27 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of MRPS27 mRNA CTD PMID:37748715 NCBI chr 2:30,740,007...30,808,577
Ensembl chr 2:30,740,033...30,808,577
JBrowse link
G Msmo1 methylsterol monooxygenase 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of MSMO1 mRNA CTD PMID:37748715 NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016
JBrowse link
G Mt2A metallothionein 2A decreases expression ISO N(4)-hydroxycytidine results in decreased expression of MT2 mRNA CTD PMID:37748715 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mtarc1 mitochondrial amidoxime reducing component 1 multiple interactions ISO [CYB5B protein co-treated with CYB5R3 protein co-treated with MTARC1 protein] results in increased reduction of N(4)-hydroxycytidine CTD PMID:22924387 NCBI chr13:96,324,377...96,362,677
Ensembl chr13:96,339,757...96,397,796
JBrowse link
G Mtarc2 mitochondrial amidoxime reducing component 2 multiple interactions ISO [CYB5B protein co-treated with CYB5R3 protein co-treated with MTARC2 protein] results in increased reduction of N(4)-hydroxycytidine CTD PMID:22924387 NCBI chr13:96,362,810...96,397,284 JBrowse link
G Mtbp MDM2 binding protein decreases expression ISO N(4)-hydroxycytidine results in decreased expression of MTBP mRNA CTD PMID:37748715 NCBI chr 7:86,973,215...87,055,775
Ensembl chr 7:86,973,069...87,050,827
JBrowse link
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like decreases expression ISO N(4)-hydroxycytidine results in decreased expression of MTHFD1L mRNA CTD PMID:37748715 NCBI chr 1:40,443,926...40,632,911
Ensembl chr 1:40,444,008...40,632,905
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase multiple interactions
increases expression
ISO 4-nitrobenzylthioinosine inhibits the reaction [N(4)-hydroxycytidine results in increased expression of MTHFD2 mRNA] CTD PMID:37748715 NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608
JBrowse link
G Mtx1 Metaxin 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of MTX1 mRNA CTD PMID:37748715 NCBI chr 2:174,615,460...174,621,383
Ensembl chr 2:174,615,461...174,620,982
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO N(4)-hydroxycytidine results in decreased expression of MYC mRNA CTD PMID:37748715 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Nabp1 nucleic acid binding protein 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of NABP1 mRNA CTD PMID:37748715 NCBI chr 9:50,098,552...50,133,982
Ensembl chr 9:50,126,726...50,134,107
JBrowse link
G Nars1 asparaginyl-tRNA synthetase 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of NARS mRNA CTD PMID:37748715 NCBI chr18:57,989,308...58,005,584
Ensembl chr18:57,989,308...58,005,622
JBrowse link
G Ncapd2 non-SMC condensin I complex, subunit D2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of NCAPD2 mRNA CTD PMID:37748715 NCBI chr 4:157,968,814...157,992,314
Ensembl chr 4:157,968,815...157,992,020
JBrowse link
G Ncapg non-SMC condensin I complex, subunit G decreases expression ISO N(4)-hydroxycytidine results in decreased expression of NCAPG mRNA CTD PMID:37748715 NCBI chr14:65,403,930...65,432,902
Ensembl chr14:65,404,163...65,432,902
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of NCOR1 mRNA CTD PMID:37748715 NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032
JBrowse link
G Nectin1 nectin cell adhesion molecule 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of PVRL1 mRNA CTD PMID:37748715 NCBI chr 8:44,101,776...44,164,863
Ensembl chr 8:44,101,776...44,189,787
JBrowse link
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase decreases expression ISO N(4)-hydroxycytidine results in decreased expression of NSF mRNA CTD PMID:37748715 NCBI chr10:88,727,912...88,857,375
Ensembl chr10:88,727,912...88,857,386
JBrowse link
G Nsun3 NOP2/Sun RNA methyltransferase 3 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of NSUN3 mRNA CTD PMID:37748715 NCBI chr11:37,490,832...37,575,607
Ensembl chr11:37,490,838...37,568,543
JBrowse link
G Ntaq1 N-terminal glutamine amidase 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of WDYHV1 mRNA CTD PMID:37748715 NCBI chr 7:89,684,318...89,704,484
Ensembl chr 7:89,684,323...89,704,474
JBrowse link
G Nup85 nucleoporin 85 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of NUP85 mRNA CTD PMID:37748715 NCBI chr10:100,806,482...100,825,029
Ensembl chr10:100,806,437...100,825,043
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator multiple interactions
increases expression
ISO 4-nitrobenzylthioinosine inhibits the reaction [N(4)-hydroxycytidine results in increased expression of NUPR1 mRNA] CTD PMID:37748715 NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281
JBrowse link
G Nxf7 nuclear RNA export factor 7 increases expression ISO N(4)-hydroxycytidine results in increased expression of NXF2 mRNA CTD PMID:37748715 NCBI chr  X:98,535,374...98,552,562
Ensembl chr  X:98,535,375...98,552,526
JBrowse link
G Ogdh oxoglutarate dehydrogenase decreases expression ISO N(4)-hydroxycytidine results in decreased expression of OGDH mRNA CTD PMID:37748715 NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479
JBrowse link
G Oip5 Opa interacting protein 5 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of OIP5 mRNA CTD PMID:37748715 NCBI chr 3:106,593,746...106,603,281
Ensembl chr 3:106,593,760...106,603,250
JBrowse link
G Optn optineurin decreases expression ISO N(4)-hydroxycytidine results in decreased expression of OPTN mRNA CTD PMID:37748715 NCBI chr17:73,209,572...73,260,251
Ensembl chr17:73,209,575...73,260,251
JBrowse link
G Osgepl1 O-sialoglycoprotein endopeptidase-like 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of OSGEPL1 mRNA CTD PMID:37748715 NCBI chr 9:48,214,995...48,229,440
Ensembl chr 9:48,215,402...48,229,388
JBrowse link
G P2rx3 purinergic receptor P2X 3 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of P2RX3 mRNA CTD PMID:37748715 NCBI chr 3:70,080,850...70,124,664
Ensembl chr 3:70,080,851...70,125,178
JBrowse link
G P2rx7 purinergic receptor P2X 7 increases expression ISO N(4)-hydroxycytidine results in increased expression of P2RX7 mRNA CTD PMID:37748715 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
JBrowse link
G P4ha2 prolyl 4-hydroxylase subunit alpha 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of P4HA2 mRNA CTD PMID:37748715 NCBI chr10:38,243,136...38,271,983
Ensembl chr10:38,243,139...38,287,314
JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of PAK2 mRNA CTD PMID:37748715 NCBI chr11:68,707,940...68,768,816
Ensembl chr11:68,707,969...68,768,816
JBrowse link
G Pde3a phosphodiesterase 3A decreases expression ISO N(4)-hydroxycytidine results in decreased expression of PDE3A mRNA CTD PMID:37748715 NCBI chr 4:174,172,804...174,443,944
Ensembl chr 4:174,172,868...174,438,274
JBrowse link
G Pde4dip phosphodiesterase 4D interacting protein decreases expression ISO N(4)-hydroxycytidine results in decreased expression of PDE4DIP mRNA CTD PMID:37748715 NCBI chr 2:185,293,236...185,490,100
Ensembl chr 2:185,293,214...185,468,379
JBrowse link
G Pds5b PDS5 cohesin associated factor B decreases expression ISO N(4)-hydroxycytidine results in decreased expression of PDS5B mRNA CTD PMID:37748715 NCBI chr12:202,481...345,596
Ensembl chr12:255,313...345,596
JBrowse link
G Pex1 peroxisomal biogenesis factor 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of PEX1 mRNA CTD PMID:37748715 NCBI chr 4:30,519,950...30,558,953
Ensembl chr 4:30,519,955...30,558,921
JBrowse link
G Pgam2 phosphoglycerate mutase 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of PGAM2 mRNA CTD PMID:37748715 NCBI chr14:80,681,796...80,683,907
Ensembl chr14:80,681,776...80,683,940
JBrowse link
G Pgp phosphoglycolate phosphatase decreases expression ISO N(4)-hydroxycytidine results in decreased expression of PGP mRNA CTD PMID:37748715 NCBI chr10:13,495,232...13,497,858
Ensembl chr10:13,494,291...13,497,858
JBrowse link
G Pmch pro-melanin-concentrating hormone decreases expression ISO N(4)-hydroxycytidine results in decreased expression of PMCH mRNA CTD PMID:37748715 NCBI chr 7:22,511,934...22,513,250
Ensembl chr 7:22,511,934...22,513,250
JBrowse link
G Polr2a RNA polymerase II subunit A decreases expression ISO N(4)-hydroxycytidine results in decreased expression of POLR2A mRNA CTD PMID:37748715 NCBI chr10:54,452,438...54,478,486
Ensembl chr10:54,452,441...54,478,455
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A decreases expression ISO N(4)-hydroxycytidine results in decreased expression of PPP1R15A mRNA CTD PMID:37748715 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Ppp1r3c protein phosphatase 1, regulatory subunit 3C decreases expression ISO N(4)-hydroxycytidine results in decreased expression of PPP1R3C mRNA CTD PMID:37748715 NCBI chr 1:234,460,958...234,465,961
Ensembl chr 1:234,460,652...234,465,961
JBrowse link
G Psat1 phosphoserine aminotransferase 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of PSAT1 mRNA CTD PMID:37748715 NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682
JBrowse link
G Psph phosphoserine phosphatase increases expression ISO N(4)-hydroxycytidine results in increased expression of PSPH mRNA CTD PMID:37748715 NCBI chr12:26,882,524...26,905,084
Ensembl chr12:26,883,133...26,905,074
JBrowse link
G Ptk2 protein tyrosine kinase 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of PTK2 mRNA CTD PMID:37748715 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
JBrowse link
G Rab21 RAB21, member RAS oncogene family decreases expression ISO N(4)-hydroxycytidine results in decreased expression of RAB21 mRNA CTD PMID:37748715 NCBI chr 7:50,904,050...50,928,890
Ensembl chr 7:50,904,057...50,928,839
JBrowse link
G Rabggta Rab geranylgeranyltransferase subunit alpha decreases expression ISO N(4)-hydroxycytidine results in decreased expression of RABGGTA mRNA CTD PMID:37748715 NCBI chr15:29,206,328...29,213,398
Ensembl chr15:29,206,157...29,213,348
JBrowse link
G Rad54l RAD54 like decreases expression ISO N(4)-hydroxycytidine results in decreased expression of RAD54L mRNA CTD PMID:37748715 NCBI chr 5:129,575,431...129,605,100
Ensembl chr 5:129,575,378...129,605,070
JBrowse link
G Reep6 receptor accessory protein 6 increases expression ISO N(4)-hydroxycytidine results in increased expression of REEP6 mRNA CTD PMID:37748715 NCBI chr 7:9,373,927...9,380,845
Ensembl chr 7:9,373,927...9,380,597
JBrowse link
G Rfc2 replication factor C subunit 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of RFC2 mRNA CTD PMID:37748715 NCBI chr12:22,120,449...22,133,576
Ensembl chr12:22,120,010...22,133,557
JBrowse link
G Rhbdd1 rhomboid domain containing 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of RHBDD1 mRNA CTD PMID:37748715 NCBI chr 9:83,630,037...83,748,690
Ensembl chr 9:83,630,063...83,748,689
JBrowse link
G Rragc Ras-related GTP binding C decreases expression ISO N(4)-hydroxycytidine results in decreased expression of RRAGC mRNA CTD PMID:37748715 NCBI chr 5:136,148,239...136,167,773
Ensembl chr 5:136,148,276...136,167,767
JBrowse link
G Rspry1 ring finger and SPRY domain containing 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of RSPRY1 mRNA CTD PMID:37748715 NCBI chr19:10,352,449...10,403,015
Ensembl chr19:10,353,821...10,401,102
JBrowse link
G Samm50 SAMM50 sorting and assembly machinery component decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SAMM50 mRNA CTD PMID:37748715 NCBI chr 7:115,317,472...115,341,682
Ensembl chr 7:115,317,404...115,341,682
JBrowse link
G Sars1 seryl-tRNA synthetase 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SARS mRNA CTD PMID:37748715 NCBI chr 2:196,065,543...196,081,240
Ensembl chr 2:196,065,430...196,081,277
JBrowse link
G Sema6a semaphorin 6A decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SEMA6A mRNA CTD PMID:37748715 NCBI chr18:40,050,623...40,171,954
Ensembl chr18:40,050,624...40,171,954
JBrowse link
G Sesn1 sestrin 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SESN1 mRNA CTD PMID:37748715 NCBI chr20:45,294,876...45,387,698
Ensembl chr20:45,294,871...45,387,697
JBrowse link
G Sesn2 sestrin 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SESN2 mRNA CTD PMID:37748715 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
JBrowse link
G Sh3tc1 SH3 domain and tetratricopeptide repeats 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SH3TC1 mRNA CTD PMID:37748715 NCBI chr14:75,005,691...75,050,001
Ensembl chr14:75,016,875...75,049,995
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SHMT2 mRNA CTD PMID:37748715 NCBI chr 7:63,358,961...63,364,293
Ensembl chr 7:63,358,961...63,364,236
JBrowse link
G Ska2 spindle and kinetochore associated complex subunit 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SKA2 mRNA CTD PMID:37748715 NCBI chr10:71,921,474...71,939,461
Ensembl chr10:71,921,582...71,939,458
JBrowse link
G Slc1a4 solute carrier family 1 member 4 increases expression ISO N(4)-hydroxycytidine results in increased expression of SLC1A4 mRNA CTD PMID:37748715 NCBI chr14:94,530,801...94,560,190
Ensembl chr14:94,529,084...94,560,418
JBrowse link
G Slc1a5 solute carrier family 1 member 5 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SLC1A5 mRNA CTD PMID:37748715 NCBI chr 1:77,456,849...77,470,952
Ensembl chr 1:77,456,694...77,470,952
JBrowse link
G Slc25a31 solute carrier family 25 member 31 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SLC25A31 mRNA CTD PMID:37748715 NCBI chr 2:123,695,387...123,711,275
Ensembl chr 2:123,695,408...123,710,795
JBrowse link
G Slc25a36 solute carrier family 25 member 36 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SLC25A36 mRNA CTD PMID:37748715 NCBI chr 8:97,659,848...97,693,735
Ensembl chr 8:97,662,127...97,693,703
JBrowse link
G Slc25a4 solute carrier family 25 member 4 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SLC25A4 mRNA CTD PMID:37748715 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733
JBrowse link
G Slc26a2 solute carrier family 26 member 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SLC26A2 mRNA CTD PMID:37748715 NCBI chr18:54,648,276...54,666,627
Ensembl chr18:54,652,951...54,666,626
JBrowse link
G Slc2a1 solute carrier family 2 member 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SLC2A1 mRNA CTD PMID:37748715 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
JBrowse link
G Slc35a4 solute carrier family 35, member A4 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SLC35A4 mRNA CTD PMID:37748715 NCBI chr18:28,280,483...28,284,610
Ensembl chr18:28,279,750...28,284,725
JBrowse link
G Slc38a1 solute carrier family 38, member 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SLC38A1 mRNA CTD PMID:37748715 NCBI chr 7:127,733,230...127,802,541
Ensembl chr 7:127,738,226...127,802,218
JBrowse link
G Slc38a2 solute carrier family 38, member 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SLC38A2 mRNA CTD PMID:37748715 NCBI chr 7:127,851,267...127,863,482
Ensembl chr 7:127,851,267...127,863,436
JBrowse link
G Slc38a7 solute carrier family 38, member 7 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SLC38A7 mRNA CTD PMID:37748715 NCBI chr19:9,209,203...9,225,472
Ensembl chr19:9,209,257...9,225,454
JBrowse link
G Slc39a4 solute carrier family 39 member 4 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SLC39A4 mRNA CTD PMID:37748715 NCBI chr 7:108,333,368...108,337,553
Ensembl chr 7:108,333,381...108,337,553
JBrowse link
G Slc3a2 solute carrier family 3 member 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SLC3A2 mRNA CTD PMID:37748715 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
JBrowse link
G Slc44a4 solute carrier family 44, member 4 multiple interactions
decreases expression
ISO 4-nitrobenzylthioinosine inhibits the reaction [N(4)-hydroxycytidine results in decreased expression of SLC44A4 mRNA] CTD PMID:37748715 NCBI chr20:3,903,099...3,919,215
Ensembl chr20:3,903,099...3,919,215
JBrowse link
G Slc6a9 solute carrier family 6 member 9 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SLC6A9 mRNA CTD PMID:37748715 NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728
JBrowse link
G Slc7a1 solute carrier family 7 member 1 multiple interactions
increases expression
ISO 4-nitrobenzylthioinosine inhibits the reaction [N(4)-hydroxycytidine results in increased expression of SLC7A1 mRNA] CTD PMID:37748715 NCBI chr12:6,628,288...6,703,849
Ensembl chr12:6,628,007...6,703,849
JBrowse link
G Slc7a3 solute carrier family 7 member 3 increases expression ISO N(4)-hydroxycytidine results in increased expression of SLC7A3 mRNA CTD PMID:37748715 NCBI chr  X:66,210,071...66,216,482
Ensembl chr  X:66,210,081...66,215,708
JBrowse link
G Slc7a5 solute carrier family 7 member 5 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SLC7A5 mRNA CTD PMID:37748715 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
JBrowse link
G Slc7a7 solute carrier family 7 member 7 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SLC7A7 mRNA CTD PMID:37748715 NCBI chr15:27,822,088...27,873,121
Ensembl chr15:27,822,091...27,865,648
JBrowse link
G Smcr8 SMCR8-C9orf72 complex subunit decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SMCR8 mRNA CTD PMID:37748715 NCBI chr10:45,457,962...45,465,101
Ensembl chr10:45,457,605...45,468,876
JBrowse link
G Smim22 small integral membrane protein 22 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SMIM22 mRNA CTD PMID:37748715 NCBI chr10:10,572,146...10,574,339 JBrowse link
G Snord1c small nucleolar RNA, C/D box 1C decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SNORD1C mRNA CTD PMID:37748715 NCBI chr10:101,905,797...101,905,872
Ensembl chr10:101,905,797...101,905,872
JBrowse link
G Snx4 sorting nexin 4 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SNX4 mRNA CTD PMID:37748715 NCBI chr11:67,460,872...67,518,143
Ensembl chr11:67,460,870...67,518,174
JBrowse link
G Spag7 sperm associated antigen 7 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SPAG7 mRNA CTD PMID:37748715 NCBI chr10:55,377,249...55,383,404
Ensembl chr10:55,377,249...55,383,404
JBrowse link
G Sqle squalene epoxidase decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SQLE mRNA CTD PMID:37748715 NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618
JBrowse link
G Srxn1 sulfiredoxin 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SRXN1 mRNA CTD PMID:37748715 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
JBrowse link
G Stc2 stanniocalcin 2 multiple interactions
increases expression
ISO 4-nitrobenzylthioinosine inhibits the reaction [N(4)-hydroxycytidine results in increased expression of STC2 mRNA] CTD PMID:37748715 NCBI chr10:16,251,046...16,260,815
Ensembl chr10:16,250,853...16,262,973
JBrowse link
G Stil STIL, centriolar assembly protein decreases expression ISO N(4)-hydroxycytidine results in decreased expression of STIL mRNA CTD PMID:37748715 NCBI chr 5:128,520,837...128,573,732
Ensembl chr 5:128,520,953...128,573,730
JBrowse link
G Stx7 syntaxin 7 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of STX7 mRNA CTD PMID:37748715 NCBI chr 1:21,197,075...21,237,320
Ensembl chr 1:21,197,075...21,237,279
JBrowse link
G Svil supervillin decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SVIL mRNA CTD PMID:37748715 NCBI chr17:52,648,502...52,844,114
Ensembl chr17:52,648,502...52,793,404
JBrowse link
G Sycp1 synaptonemal complex protein 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of SYCP1 mRNA CTD PMID:37748715 NCBI chr 2:190,296,688...190,456,687
Ensembl chr 2:190,296,954...190,456,737
JBrowse link
G Tars1 threonyl-tRNA synthetase 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TARS mRNA CTD PMID:37748715 NCBI chr 2:60,368,893...60,387,715
Ensembl chr 2:60,367,796...60,387,717
JBrowse link
G Tas2r108 taste receptor, type 2, member 108 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TAS2R108 mRNA CTD PMID:37748715 NCBI chr 4:69,287,667...69,288,581
Ensembl chr 4:69,287,667...69,288,581
JBrowse link
G Tat tyrosine aminotransferase decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TAT mRNA CTD PMID:37748715 NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031
JBrowse link
G Tbcc tubulin folding cofactor C decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TBCC mRNA CTD PMID:37748715 NCBI chr 9:14,098,855...14,100,043
Ensembl chr 9:14,098,868...14,100,042
JBrowse link
G Tdg thymine-DNA glycosylase decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TDG mRNA CTD PMID:37748715 NCBI chr 7:21,077,853...21,097,617
Ensembl chr 7:21,077,853...21,097,567
JBrowse link
G Tec tec protein tyrosine kinase decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TEC mRNA CTD PMID:37748715 NCBI chr14:35,352,551...35,461,585
Ensembl chr14:35,352,829...35,461,557
JBrowse link
G Terf1 telomeric repeat binding factor 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TERF1 mRNA CTD PMID:37748715 NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340
JBrowse link
G Thap4 THAP domain containing 4 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of THAP4 mRNA CTD PMID:37748715 NCBI chr 9:94,242,581...94,282,312
Ensembl chr 9:94,242,581...94,282,306
JBrowse link
G Tmppe transmembrane protein with metallophosphoesterase domain decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TMPPE mRNA CTD PMID:37748715 NCBI chr 8:114,085,497...114,093,388
Ensembl chr 8:114,084,831...114,094,286
JBrowse link
G Top2a DNA topoisomerase II alpha decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TOP2A mRNA CTD PMID:37748715 NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874
JBrowse link
G Tor1aip1 torsin 1A interacting protein 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TOR1AIP1 mRNA CTD PMID:37748715 NCBI chr13:68,196,681...68,226,121
Ensembl chr13:68,196,681...68,225,862
JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TRP53INP1 mRNA CTD PMID:37748715 NCBI chr 5:24,253,986...24,272,250
Ensembl chr 5:24,260,568...24,267,968
JBrowse link
G Tpcn2 two pore segment channel 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TPCN2 mRNA CTD PMID:37748715 NCBI chr 1:200,416,538...200,446,252
Ensembl chr 1:200,416,540...200,446,236
JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression
multiple interactions
ISO N(4)-hydroxycytidine results in increased expression of TRIB3 mRNA
4-nitrobenzylthioinosine inhibits the reaction [N(4)-hydroxycytidine results in increased expression of TRIB3 mRNA]
CTD PMID:37748715 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
JBrowse link
G Trim32 tripartite motif-containing 32 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TRIM32 mRNA CTD PMID:37748715 NCBI chr 5:79,005,139...79,016,615
Ensembl chr 5:78,999,389...79,022,018
JBrowse link
G Trip12 thyroid hormone receptor interactor 12 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TRIP12 mRNA CTD PMID:37748715 NCBI chr 9:85,916,691...86,043,312
Ensembl chr 9:85,916,691...86,051,403
JBrowse link
G Trpm6 transient receptor potential cation channel, subfamily M, member 6 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TRPM6 mRNA CTD PMID:37748715 NCBI chr 1:216,136,407...216,320,523
Ensembl chr 1:216,170,038...216,320,520
JBrowse link
G Tubb5 tubulin, beta 5 class I decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TUBB5 mRNA CTD PMID:37748715 NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940
JBrowse link
G Tug1 taurine up-regulated 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TUG1 mRNA CTD PMID:37748715 NCBI chr14:78,519,894...78,526,927
Ensembl chr14:78,522,506...78,526,927
JBrowse link
G Txnip thioredoxin interacting protein decreases expression ISO N(4)-hydroxycytidine results in decreased expression of TXNIP mRNA CTD PMID:37748715 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase decreases expression ISO N(4)-hydroxycytidine results in decreased expression of UGDH mRNA CTD PMID:37748715 NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354
JBrowse link
G Vangl1 VANGL planar cell polarity protein 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of VANGL1 mRNA CTD PMID:37748715 NCBI chr 2:189,586,681...189,637,609
Ensembl chr 2:189,589,229...189,637,619
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO N(4)-hydroxycytidine results in decreased expression of VEGFA mRNA CTD PMID:37748715 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vtcn1 V-set domain containing T cell activation inhibitor 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of VTCN1 mRNA CTD PMID:37748715 NCBI chr 2:188,253,594...188,321,658
Ensembl chr 2:188,253,594...188,321,658
JBrowse link
G Yars1 tyrosyl-tRNA synthetase 1 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of YARS mRNA CTD PMID:37748715 NCBI chr 5:141,535,815...141,564,029
Ensembl chr 5:141,535,759...141,563,833
JBrowse link
G Yipf2 Yip1 domain family, member 2 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of YIPF2 mRNA CTD PMID:37748715 NCBI chr 8:20,141,148...20,145,349
Ensembl chr 8:20,141,155...20,145,339
JBrowse link
G Ypel5 yippee-like 5 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of YPEL5 mRNA CTD PMID:37748715 NCBI chr 6:22,656,284...22,671,741
Ensembl chr 6:22,656,285...22,671,691
JBrowse link
G Zfp516 zinc finger protein 516 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ZFP516 mRNA CTD PMID:37748715 NCBI chr18:76,286,453...76,386,526
Ensembl chr18:76,302,096...76,385,269
JBrowse link
G Zswim5 zinc finger, SWIM-type containing 5 decreases expression ISO N(4)-hydroxycytidine results in decreased expression of ZSWIM5 mRNA CTD PMID:37748715 NCBI chr 5:130,346,733...130,463,791
Ensembl chr 5:130,343,034...130,463,784
JBrowse link
norgestimate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 decreases activity ISO norgestimate results in decreased activity of ABCC2 protein CTD PMID:16049127 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Ar androgen receptor multiple interactions
affects localization
decreases expression
ISO norgestimate binds to and results in decreased activity of AR protein; norgestimate binds to and results in increased activity of AR protein
norgestimate affects the localization of AR protein
norgestimate results in decreased expression of AR mRNA
CTD PMID:17505938 PMID:28478275 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Crp C-reactive protein multiple interactions ISO [Ethinyl Estradiol co-treated with norgestimate] results in increased expression of CRP protein CTD PMID:16982228 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO [Ethinyl Estradiol co-treated with norgestimate] results in decreased activity of CYP1A2 protein CTD PMID:16291717 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 multiple interactions ISO [Ethinyl Estradiol co-treated with norgestimate] results in decreased activity of CYP2C19 protein CTD PMID:16291717 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G F7 coagulation factor VII multiple interactions ISO [Ethinyl Estradiol co-treated with norgestimate] results in increased expression of F7 protein CTD PMID:12618251 NCBI chr16:76,489,775...76,500,636
Ensembl chr16:76,489,717...76,500,610
JBrowse link
G F8 coagulation factor VIII multiple interactions ISO [Ethinyl Estradiol co-treated with norgestimate] results in increased expression of F8 protein CTD PMID:12618251 NCBI chr18:140,848...172,330
Ensembl chr18:140,955...171,857
JBrowse link
G Fga fibrinogen alpha chain multiple interactions ISO [Ethinyl Estradiol co-treated with norgestimate] results in increased expression of [FGA protein binds to FGB protein binds to FGG protein] CTD PMID:12618251 NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528
JBrowse link
G Fgb fibrinogen beta chain multiple interactions ISO [Ethinyl Estradiol co-treated with norgestimate] results in increased expression of [FGA protein binds to FGB protein binds to FGG protein] CTD PMID:12618251 NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
JBrowse link
G Fgg fibrinogen gamma chain multiple interactions ISO [Ethinyl Estradiol co-treated with norgestimate] results in increased expression of [FGA protein binds to FGB protein binds to FGG protein] CTD PMID:12618251 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
JBrowse link
G Pgr progesterone receptor multiple interactions ISO norgestimate binds to and affects the activity of PGR protein CTD PMID:1324557 PMID:15697108 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Plat plasminogen activator, tissue type multiple interactions ISO [Ethinyl Estradiol co-treated with norgestimate] results in decreased expression of PLAT protein; [Ethinyl Estradiol co-treated with norgestimate] results in increased activity of PLAT protein CTD PMID:12618251 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
JBrowse link
G Plg plasminogen multiple interactions ISO [Ethinyl Estradiol co-treated with norgestimate] results in increased expression of PLG protein CTD PMID:12618251 NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786
JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa multiple interactions ISO [Ethinyl Estradiol co-treated with norgestimate] results in increased expression of PROC protein CTD PMID:12618251 NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133
JBrowse link
G Pros1 protein S multiple interactions ISO [Ethinyl Estradiol co-treated with norgestimate] results in decreased expression of PROS1 protein CTD PMID:12618251 NCBI chr11:230,597...311,288
Ensembl chr11:230,696...311,286
JBrowse link
G Serpina6 serpin family A member 6 multiple interactions ISO [Ethinyl Estradiol co-treated with norgestimate] results in increased expression of SERPINA6 protein CTD PMID:16982228 NCBI chr 6:122,780,040...122,790,274
Ensembl chr 6:122,780,043...122,790,349
JBrowse link
G Serpina7 serpin family A member 7 multiple interactions ISO [Ethinyl Estradiol co-treated with norgestimate] results in increased expression of SERPINA7 protein CTD PMID:16982228 NCBI chr  X:102,663,242...102,722,319
Ensembl chr  X:102,663,405...102,669,040
JBrowse link
G Serpinc1 serpin family C member 1 multiple interactions ISO [Ethinyl Estradiol co-treated with norgestimate] results in decreased expression of SERPINC1 protein CTD PMID:12618251 NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293
JBrowse link
G Shbg sex hormone binding globulin multiple interactions ISO [Ethinyl Estradiol co-treated with norgestimate] results in increased expression of SHBG protein CTD PMID:12586319 PMID:16982228 NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057
JBrowse link
phoxim term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity EXP
ISO
phoxim metabolite results in decreased activity of ACHE protein; phoxim results in decreased activity of ACHE protein CTD PMID:15793557 PMID:33497710 PMID:33844597 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Ar androgen receptor multiple interactions ISO phoxim inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein] CTD PMID:33049310 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Arl6ip5 ADP-ribosylation factor like GTPase 6 interacting protein 5 affects expression ISO phoxim affects the expression of ARL6IP5 protein CTD PMID:15799245 NCBI chr 4:129,810,650...129,838,628
Ensembl chr 4:129,810,645...129,838,608
JBrowse link
G Bche butyrylcholinesterase decreases activity EXP phoxim metabolite results in decreased activity of BCHE protein CTD PMID:33497710 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha increases expression
multiple interactions
ISO phoxim results in increased expression of CEBPA protein
Fulvestrant inhibits the reaction [phoxim results in increased expression of CEBPA protein]
CTD PMID:33872936 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Cldn4 claudin 4 decreases expression
multiple interactions
EXP phoxim results in decreased expression of CLDN4 mRNA
Vitamin E inhibits the reaction [phoxim results in decreased expression of CLDN4 mRNA]
CTD PMID:30003487 NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP phoxim results in increased expression of CYP2B1 mRNA CTD PMID:36356836 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
affects binding
ISO phoxim binds to and results in increased activity of ESR1 protein
phoxim binds to ESR1 protein
CTD PMID:33049310 PMID:33872936 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Fas Fas cell surface death receptor increases expression
multiple interactions
ISO phoxim results in increased expression of FAS mRNA
Fulvestrant inhibits the reaction [phoxim results in increased expression of FAS mRNA]
CTD PMID:33872936 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression
multiple interactions
EXP phoxim results in increased expression of GPX2 mRNA
Vitamin E inhibits the reaction [phoxim results in increased expression of GPX2 mRNA]
CTD PMID:30003487 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
JBrowse link
G Il1b interleukin 1 beta decreases expression EXP phoxim results in decreased expression of IL1B mRNA CTD PMID:30003487 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 decreases expression
multiple interactions
EXP phoxim results in decreased expression of IL6 mRNA
Vitamin E inhibits the reaction [phoxim results in decreased expression of IL6 mRNA]
CTD PMID:30003487 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Irs2 insulin receptor substrate 2 decreases expression EXP phoxim results in decreased expression of IRS2 mRNA CTD PMID:30090575 NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482
JBrowse link
G Lpl lipoprotein lipase increases expression
multiple interactions
ISO phoxim results in increased expression of LPL mRNA
Fulvestrant inhibits the reaction [phoxim results in increased expression of LPL mRNA]
CTD PMID:33872936 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression EXP phoxim results in increased expression of NFE2L2 mRNA CTD PMID:30003487 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO phoxim binds to and results in increased activity of NR1I2 protein CTD PMID:33049310 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Ocln occludin multiple interactions
decreases expression
EXP Vitamin E inhibits the reaction [phoxim results in decreased expression of OCLN mRNA] CTD PMID:30003487 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
JBrowse link
G Plin1 perilipin 1 multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [phoxim results in increased expression of PLIN1 protein]; tolclofos-methyl inhibits the reaction [phoxim results in increased expression of PLIN1 protein] CTD PMID:33872936 NCBI chr 1:133,664,294...133,676,854
Ensembl chr 1:133,664,892...133,676,828
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
increases expression
ISO phoxim binds to and results in increased activity of PPARG protein
phoxim results in increased expression of PPARG protein
Fulvestrant inhibits the reaction [phoxim results in increased expression of PPARG protein]; phoxim binds to and results in increased activity of PPARG protein
CTD PMID:33049310 PMID:33872936 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO phoxim binds to and results in decreased activity of THRA protein CTD PMID:33049310 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
EXP Vitamin E inhibits the reaction [phoxim results in increased expression of TNF protein]
phoxim results in increased expression of TNF mRNA; phoxim results in increased expression of TNF protein
CTD PMID:30003487 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 affects activity ISO phoxim metabolite affects the activity of TP53 protein CTD PMID:35435491 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19915
    chemical entity 19913
      atom 19895
        nonmetal atom 19817
          nitrogen atom 18987
            nitrogen molecular entity 18987
              oxime 428
                D-Glucose oxime 0
                aci-nitro compound + 0
                aldoxime + 86
                ketoxime + 352
Path 2
Term Annotations click to browse term
  CHEBI ontology 19915
    subatomic particle 19913
      composite particle 19895
        hadron 19895
          baryon 19913
            nucleon 19895
              atomic nucleus 19913
                atom 19895
                  main group element atom 19852
                    main group molecular entity 19834
                      p-block molecular entity 19834
                        pnictogen molecular entity 19107
                          nitrogen molecular entity 18987
                            oxime 428
                              D-Glucose oxime 0
                              aci-nitro compound + 0
                              aldoxime + 86
                              ketoxime + 352
paths to the root