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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:hydroxy-amino acid
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Accession:CHEBI:24662 term browser browse the term
Definition:A non-proteinogenic alpha-amino acid bearing one or more hydroxy groups at unspecified positions.


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3-hydroxykynurenine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kmo kynurenine 3-monooxygenase multiple interactions EXP [KMO protein results in increased hydroxylation of Kynurenine] which results in increased chemical synthesis of 3-hydroxykynurenine CTD PMID:32243540 NCBI chr13:90,089,340...90,121,108
Ensembl chr13:90,089,463...90,125,151 		JBrowse link
5-hydroxytryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afp alpha-fetoprotein decreases expression ISO 5-Hydroxytryptophan results in decreased expression of AFP mRNA CTD PMID:32926198 NCBI chr14:17,857,584...17,875,645
Ensembl chr14:17,857,584...17,875,649 		JBrowse link
G Ddc dopa decarboxylase multiple interactions EXP [DDC protein results in decreased carboxylation of 5-Hydroxytryptophan] which results in increased chemical synthesis of Serotonin CTD PMID:32243540 NCBI chr14:90,592,304...90,682,830
Ensembl chr14:90,592,304...90,682,806 		JBrowse link
G Gata4 GATA binding protein 4 decreases expression ISO 5-Hydroxytryptophan results in decreased expression of GATA4 mRNA CTD PMID:32926198 NCBI chr15:41,635,572...41,707,252
Ensembl chr15:41,635,572...41,681,609 		JBrowse link
G Nanog Nanog homeobox decreases expression ISO 5-Hydroxytryptophan results in decreased expression of NANOG mRNA CTD PMID:32926198 NCBI chr 4:157,615,687...157,623,061
Ensembl chr 4:157,615,687...157,623,061 		JBrowse link
G Pou5f1 POU class 5 homeobox 1 decreases expression ISO 5-Hydroxytryptophan results in decreased expression of POU5F1 mRNA CTD PMID:32926198 NCBI chr20:3,227,836...3,232,598
Ensembl chr20:3,227,837...3,232,598 		JBrowse link
G Tph1 tryptophan hydroxylase 1 multiple interactions EXP [TPH1 protein results in increased hydroxylation of Tryptophan] which results in increased chemical synthesis of 5-Hydroxytryptophan CTD PMID:32243540 NCBI chr 1:106,293,695...106,314,628
Ensembl chr 1:106,085,953...106,312,484 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    role 20820
      application 20621
        NMR chemical shift reference compound 18453
          ammonia 18261
            organic amino compound 18261
              amino acid 16340
                alpha-amino acid 14255
                  non-proteinogenic alpha-amino acid 3854
                    hydroxy-amino acid 7
                      2-methylserine + 0
                      3-hydroxyaspartic acid + 0
                      3-hydroxylysine 0
                      4-hydroxy-4-methylglutamic acid + 0
                      4-hydroxy-L-threonine 0
                      4-hydroxyphenylglycine + 0
                      N-hydroxy-alpha-amino-acid + 0
                      alpha-hydroxyglycine + 0
                      hydroxy-L-arginine + 0
                      hydroxy-L-glutamic acid + 0
                      hydroxy-L-isoleucine + 0
                      hydroxy-L-lysine + 0
                      hydroxy-L-valine + 0
                      hydroxyarginine + 0
                      hydroxykynurenine + 1
                      hydroxylysine + 0
                      hydroxyphenylalanine + 0
                      hydroxyproline + 0
                      hydroxytryptophan + 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    main group molecular entity 20781
                      s-block molecular entity 20574
                        hydrogen molecular entity 20558
                          hydrides 19693
                            inorganic hydride 18602
                              pnictogen hydride 18589
                                nitrogen hydride 18502
                                  azane 18262
                                    ammonia 18261
                                      organic amino compound 18261
                                        amino acid 16340
                                          non-proteinogenic amino acid 4058
                                            non-proteinogenic alpha-amino acid 3854
                                              hydroxy-amino acid 7
                                                2-methylserine + 0
                                                3-hydroxyaspartic acid + 0
                                                3-hydroxylysine 0
                                                4-hydroxy-4-methylglutamic acid + 0
                                                4-hydroxy-L-threonine 0
                                                4-hydroxyphenylglycine + 0
                                                N-hydroxy-alpha-amino-acid + 0
                                                alpha-hydroxyglycine + 0
                                                hydroxy-L-arginine + 0
                                                hydroxy-L-glutamic acid + 0
                                                hydroxy-L-isoleucine + 0
                                                hydroxy-L-lysine + 0
                                                hydroxy-L-valine + 0
                                                hydroxyarginine + 0
                                                hydroxykynurenine + 1
                                                hydroxylysine + 0
                                                hydroxyphenylalanine + 0
                                                hydroxyproline + 0
                                                hydroxytryptophan + 6
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