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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:hydroquinones
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Accession:CHEBI:24646 term browser browse the term
Definition:Benzenediols that have the hydroxy substituents in the 1- and 4-positions.
Synonyms:related_synonym: 1,4-benzoquinols;   Formula=C6H2O2R4;   SMILES=OC1=C(*)C(*)=C(O)C(*)=C1*;   a 1,4-benzoquinol;   a quinol;   benzene-1,4-diols
 alt_id: CHEBI:134188;   MESH:D006873
 xref_mesh: MESH:D006873


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hydroquinones term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfe2l2 NFE2 like bZIP transcription factor 2 decreases response to substance ISO NFE2L2 protein results in decreased susceptibility to Hydroquinones CTD PMID:20932822 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
1,4-dihydroxy-2-naphthoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO 1,4-dihydroxy-2-naphthoic acid binds to and results in increased activity of AHR protein; [1,4-dihydroxy-2-naphthoic acid binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; [1,4-dihydroxy-2-naphthoic acid binds to and results in increased activity of AHR protein] which results in increased expression of CYP1B1 mRNA CTD PMID:27837168 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO [1,4-dihydroxy-2-naphthoic acid binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA CTD PMID:27837168 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO [1,4-dihydroxy-2-naphthoic acid binds to and results in increased activity of AHR protein] which results in increased expression of CYP1B1 mRNA CTD PMID:27837168 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Gpr35 G protein-coupled receptor 35 multiple interactions ISO 1,4-dihydroxy-2-naphthoic acid binds to and results in increased activity of GPR35 protein CTD PMID:20826425 NCBI chr 9:93,527,165...93,539,573
Ensembl chr 9:93,527,127...93,539,299 		JBrowse link
2,5-di-tert-butylbenzene-1,4-diol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO 2,5-di-tert-butylhydroquinone inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein] CTD PMID:33049310 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression EXP 2,5-di-tert-butylhydroquinone results in increased expression of GSTP1 protein CTD PMID:12680784 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases response to substance ISO NFE2L2 gene mutant form results in increased susceptibility to 2,5-di-tert-butylhydroquinone CTD PMID:12842875 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO 2,5-di-tert-butylhydroquinone binds to and results in increased activity of NR1I2 protein CTD PMID:33049310 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO 2,5-di-tert-butylhydroquinone binds to and results in increased activity of PPARG protein CTD PMID:33049310 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
2,5-dihydroxycinnamic acid methyl ester term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf2 colony stimulating factor 2 multiple interactions ISO CSF2 protein affects the susceptibility to [Nitroblue Tetrazolium co-treated with methyl 2,5-dihydroxycinnamate] CTD PMID:8471626 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
2-tert-butylhydroquinone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of ABCC1 mRNA; 2-tert-butylhydroquinone results in increased expression of ABCC1 protein CTD PMID:11836020 PMID:16014739 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression ISO
EXP		 2-tert-butylhydroquinone results in increased expression of ABCC2 mRNA; 2-tert-butylhydroquinone results in increased expression of ABCC2 protein CTD PMID:11264000 PMID:11836020 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression
multiple interactions		 ISO 2-tert-butylhydroquinone results in increased expression of ABCG2 mRNA; 2-tert-butylhydroquinone results in increased expression of ABCG2 protein
AHR protein promotes the reaction [2-tert-butylhydroquinone results in increased expression of ABCG2 protein]		 CTD PMID:17077187 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide increases expression ISO 2-tert-butylhydroquinone results in increased expression of ADH7 mRNA CTD PMID:16014739 NCBI chr 2:226,748,724...226,763,183
Ensembl chr 2:226,741,788...226,763,182 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO
EXP		 AHR protein promotes the reaction [2-tert-butylhydroquinone results in increased expression of ABCG2 protein]; AHR protein promotes the reaction [2-tert-butylhydroquinone results in increased expression of UGT1A6 mRNA]
2-tert-butylhydroquinone results in increased activity of and results in increased localization of AHR protein		 CTD PMID:12948865 PMID:15608132 PMID:17077187 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO 2-tert-butylhydroquinone results in increased expression of AKR1B10 mRNA CTD PMID:30806763 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of AKR1C1 mRNA CTD PMID:9973208 PMID:30806763 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of AKT1 protein] CTD PMID:23112101 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Ar androgen receptor multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; 2-tert-butylhydroquinone inhibits the reaction [Metribolone results in increased activity of AR protein] CTD PMID:18324785 PMID:33049310 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [thallium nitrate results in decreased expression of ATP5F1A protein] CTD PMID:31726083 NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794 		JBrowse link
G B4galt1 beta-1,4-galactosyltransferase 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of B4GALT1 mRNA CTD PMID:35724838 NCBI chr 5:55,935,614...55,982,461
Ensembl chr 5:55,935,615...55,982,461 		JBrowse link
G Bach1 BTB domain and CNC homolog 1 affects localization
multiple interactions		 ISO 2-tert-butylhydroquinone affects the localization of BACH1 protein
2-tert-butylhydroquinone promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of BACH1 protein]; [ferric chloride results in increased oxidation of 2-tert-butylhydroquinone] promotes the reaction [2-tert-butylhydroquinone analog binds to BACH1 protein]		 CTD PMID:28645578 NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
multiple interactions		 ISO
EXP		 2-tert-butylhydroquinone results in decreased expression of BAX protein
[2-tert-butylhydroquinone results in increased stability of NFE2L2 protein] which results in decreased expression of BAX protein
2-tert-butylhydroquinone inhibits the reaction [sodium arsenite results in increased expression of BAX protein]
2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in increased expression of BAX mRNA]; 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of BAX protein]; 2-tert-butylhydroquinone inhibits the reaction [Matrines results in increased expression of BAX protein]		 CTD PMID:22275372 PMID:26878773 PMID:28583816 PMID:32565124 PMID:37075934 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression		 ISO
EXP		 2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to BCL2 promoter]; [2-tert-butylhydroquinone results in increased stability of NFE2L2 protein] which results in increased expression of BCL2 protein; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of BCL2 mRNA]
2-tert-butylhydroquinone results in increased expression of BCL2 protein
2-tert-butylhydroquinone results in increased expression of BCL2 mRNA; 2-tert-butylhydroquinone results in increased expression of BCL2 protein
2-tert-butylhydroquinone inhibits the reaction [Atorvastatin results in decreased expression of BCL2 protein]; 2-tert-butylhydroquinone inhibits the reaction [sodium arsenite results in decreased expression of BCL2 protein]
2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of BCL2 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in decreased expression of BCL2 protein]; 2-tert-butylhydroquinone inhibits the reaction [Matrines results in decreased expression of BCL2 protein]		 CTD PMID:22275372 PMID:26878773 PMID:28583816 PMID:31423616 PMID:32565124 More... NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bco2 beta-carotene oxygenase 2 increases expression ISO 2-tert-butylhydroquinone results in increased expression of BCO2 mRNA CTD PMID:16014739 NCBI chr 8:50,882,174...50,907,676
Ensembl chr 8:50,882,181...50,915,467 		JBrowse link
G Blvrb biliverdin reductase B increases expression ISO 2-tert-butylhydroquinone results in increased expression of BLVRB mRNA CTD PMID:16014739 NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO
EXP		 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of CASP3 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; 2-tert-butylhydroquinone inhibits the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP3 protein]
2-tert-butylhydroquinone inhibits the reaction [Atorvastatin results in increased cleavage of CASP3 protein]; 2-tert-butylhydroquinone inhibits the reaction [hydroquinone results in increased cleavage of CASP3 protein]; 2-tert-butylhydroquinone inhibits the reaction [pterostilbene results in increased activity of CASP3 protein]; 2-tert-butylhydroquinone inhibits the reaction [sodium arsenite results in increased activity of CASP3 protein]; solanesol promotes the reaction [2-tert-butylhydroquinone inhibits the reaction [Ethanol results in increased cleavage of CASP3 protein]]
2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in increased expression of CASP3 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased cleavage of CASP3 protein]		 CTD PMID:22275372 PMID:25341683 PMID:25645596 PMID:26878773 PMID:28583816 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp4 caspase 4 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [pterostilbene results in increased activity of CASP4 protein] CTD PMID:25341683 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
G Casp7 caspase 7 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [Etoposide results in increased activity of CASP7 protein] CTD PMID:22275372 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Cat catalase multiple interactions
increases activity		 ISO
EXP		 2-tert-butylhydroquinone inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]
2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased activity of CAT protein]; 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of CAT mRNA]
2-tert-butylhydroquinone results in increased activity of CAT protein		 CTD PMID:26878773 PMID:32428544 PMID:32565124 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cbr3 carbonyl reductase 3 increases expression ISO 2-tert-butylhydroquinone results in increased expression of CBR3 mRNA CTD PMID:16014739 NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO 2-tert-butylhydroquinone results in increased expression of CCL2 mRNA CTD PMID:35724838 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression ISO 2-tert-butylhydroquinone results in increased expression of CCL20 mRNA CTD PMID:35724838 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases secretion ISO 2-tert-butylhydroquinone results in increased secretion of CCL5 protein CTD PMID:30806763 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression ISO 2-tert-butylhydroquinone results in decreased expression of CCN2 mRNA CTD PMID:16014739 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Ccnd1 cyclin D1 increases expression
multiple interactions		 ISO 2-tert-butylhydroquinone results in increased expression of CCND1 protein
2-tert-butylhydroquinone promotes the reaction [sodium arsenite results in increased expression of CCND1 protein]		 CTD PMID:26878773 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Cd5l Cd5 molecule-like increases expression ISO 2-tert-butylhydroquinone results in increased expression of CD5L mRNA CTD PMID:16014739 NCBI chr 2:172,791,007...172,802,018
Ensembl chr 2:172,790,934...172,829,753 		JBrowse link
G Cd69 Cd69 molecule multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD69 protein] CTD PMID:30171972 NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542 		JBrowse link
G Cd86 CD86 molecule increases expression ISO 2-tert-butylhydroquinone results in increased expression of CD86 protein CTD PMID:19033392 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 multiple interactions
increases expression		 ISO 2-tert-butylhydroquinone inhibits the reaction [sodium arsenite results in decreased expression of CDK4 protein]
2-tert-butylhydroquinone results in increased expression of CDK4 protein		 CTD PMID:26878773 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Ces1d carboxylesterase 1D multiple interactions
increases expression		 ISO 2-tert-butylhydroquinone results in increased expression of and results in increased activity of CES1 protein alternative form; NFE2L2 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of CES1 mRNA alternative form] CTD PMID:19715681 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Crebbp CREB binding protein multiple interactions ISO 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [2-tert-butylhydroquinone promotes the reaction [CREBBP protein binds to NFE2L2 protein]]; 2-tert-butylhydroquinone promotes the reaction [CREBBP protein binds to NFE2L2 protein]; Egtazic Acid inhibits the reaction [2-tert-butylhydroquinone promotes the reaction [CREBBP protein binds to NFE2L2 protein]] CTD PMID:21443188 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888 		JBrowse link
G Creg2 cellular repressor of E1A-stimulated genes 2 affects response to substance ISO CREG2 gene SNP affects the susceptibility to 2-tert-butylhydroquinone CTD PMID:25622337 NCBI chr 9:41,872,000...41,945,413
Ensembl chr 9:41,902,304...41,945,095 		JBrowse link
G Csf1 colony stimulating factor 1 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of AKT1 protein]; 2-tert-butylhydroquinone inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased secretion of HMGB1 protein]; [2-tert-butylhydroquinone co-treated with CSF1 protein co-treated with TNFSF11 protein] results in decreased expression of CSF1R protein; [2-tert-butylhydroquinone co-treated with CSF1 protein co-treated with TNFSF11 protein] results in increased expression of HMOX1 protein; [TNFSF11 protein co-treated with CSF1 protein co-treated with 2-tert-butylhydroquinone] results in decreased expression of CTSK protein; [TNFSF11 protein co-treated with CSF1 protein co-treated with 2-tert-butylhydroquinone] results in decreased expression of NFATC1 protein CTD PMID:23112101 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704 		JBrowse link
G Csf1r colony stimulating factor 1 receptor multiple interactions ISO [2-tert-butylhydroquinone co-treated with CSF1 protein co-treated with TNFSF11 protein] results in decreased expression of CSF1R protein; [TNFSF11 protein co-treated with 2-tert-butylhydroquinone] results in decreased expression of CSF1R protein CTD PMID:23112101 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Ctsk cathepsin K multiple interactions ISO [TNFSF11 protein co-treated with CSF1 protein co-treated with 2-tert-butylhydroquinone] results in decreased expression of CTSK protein CTD PMID:23112101 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550 		JBrowse link
G Cul3 cullin 3 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [KEAP1 protein binds to CUL3 protein] CTD PMID:18417180 PMID:30261176 NCBI chr 9:81,592,641...81,670,428
Ensembl chr 9:81,592,641...81,670,462 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of CXCL1 mRNA CTD PMID:30806763 PMID:35724838 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression ISO 2-tert-butylhydroquinone results in increased expression of CXCL2 mRNA CTD PMID:35724838 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression ISO 2-tert-butylhydroquinone results in increased expression of CXCL1 mRNA CTD PMID:30806763 PMID:35724838 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511 		JBrowse link
G Cyb5a cytochrome b5 type A increases expression ISO 2-tert-butylhydroquinone results in increased expression of CYB5A mRNA CTD PMID:16014739 NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535
Ensembl chr18:78,202,342...78,258,535 		JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [Sodium Chloride, Dietary results in increased expression of CYBB protein] CTD PMID:28844481 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586 		JBrowse link
G Cycs cytochrome c, somatic increases expression
multiple interactions		 ISO 2-tert-butylhydroquinone results in increased expression of CYCS protein
2-tert-butylhydroquinone inhibits the reaction [Atorvastatin affects the localization of CYCS protein]; 2-tert-butylhydroquinone inhibits the reaction [hydroquinone results in increased expression of CYCS protein]		 CTD PMID:31423616 PMID:35123993 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of CYP11A1 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of CYP11A1 protein] CTD PMID:32565124 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
increases activity		 ISO 2-tert-butylhydroquinone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; 2-tert-butylhydroquinone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; 2-tert-butylhydroquinone promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; 2-tert-butylhydroquinone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; FH535 inhibits the reaction [2-tert-butylhydroquinone results in increased expression of CYP1A1 mRNA]; resveratrol inhibits the reaction [2-tert-butylhydroquinone results in increased activity of CYP1A1 protein]; resveratrol inhibits the reaction [2-tert-butylhydroquinone results in increased expression of CYP1A1 mRNA]
2-tert-butylhydroquinone results in increased expression of and results in increased activity of CYP1A1 protein; resveratrol inhibits the reaction [2-tert-butylhydroquinone results in increased activity of CYP1A1 protein]		 CTD PMID:9973208 PMID:15608132 PMID:15627257 PMID:16581943 PMID:25174530 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 increases expression ISO 2-tert-butylhydroquinone results in increased expression of CYP2C19 mRNA; 2-tert-butylhydroquinone results in increased expression of CYP2C19 protein CTD PMID:24830941 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression		 ISO 2-tert-butylhydroquinone inhibits the reaction [pterostilbene results in increased expression of DDIT3 protein]
2-tert-butylhydroquinone results in increased expression of DDIT3 protein		 CTD PMID:25341683 PMID:35724838 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Dsc3 desmocollin 3 increases expression ISO 2-tert-butylhydroquinone results in increased expression of DSC3 mRNA CTD PMID:16014739 NCBI chr18:11,379,759...11,413,797
Ensembl chr18:11,377,347...11,413,797 		JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of DUSP1 mRNA CTD PMID:30806763 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Edn1 endothelin 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of EDN1 mRNA CTD PMID:35724838 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Egf epidermal growth factor multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [arsenite results in increased expression of and results in increased secretion of EGF protein] CTD PMID:36343453 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [pterostilbene results in increased phosphorylation of EIF2AK3 protein] CTD PMID:25341683 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression
multiple interactions		 EXP
ISO		 2-tert-butylhydroquinone results in increased expression of EPHX1 mRNA
2-tert-butylhydroquinone results in increased expression of EPHX1 exon; 2-tert-butylhydroquinone results in increased expression of EPHX1 protein alternative form
NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of EPHX1 exon]		 CTD PMID:20650352 PMID:24704207 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Esd esterase D increases expression ISO 2-tert-butylhydroquinone results in increased expression of ESD mRNA CTD PMID:16014739 NCBI chr15:50,043,634...50,063,134
Ensembl chr15:50,043,632...50,063,144 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO 2-tert-butylhydroquinone binds to and results in increased activity of ESR1 protein CTD PMID:33049310 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO 2-tert-butylhydroquinone binds to and results in increased activity of ESR2 protein CTD PMID:33049310 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Fgf1 fibroblast growth factor 1 multiple interactions EXP 2-tert-butylhydroquinone promotes the reaction [FGF1 protein results in increased abundance of and results in increased secretion of Glutathione]; FGF1 protein promotes the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 protein] CTD PMID:16524372 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357 		JBrowse link
G Fgf18 fibroblast growth factor 18 decreases expression ISO 2-tert-butylhydroquinone results in decreased expression of FGF18 mRNA CTD PMID:16014739 NCBI chr10:17,706,011...17,737,702
Ensembl chr10:17,706,174...17,736,818 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions		 ISO
EXP		 2-tert-butylhydroquinone results in increased expression of FOS protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [2-tert-butylhydroquinone results in increased expression of FOS protein]; 2-tert-butylhydroquinone promotes the reaction [FOS protein binds to CYP2C9 promoter]
2-tert-butylhydroquinone inhibits the reaction [Sodium Chloride, Dietary results in increased expression of FOS protein]		 CTD PMID:24830941 PMID:28844481 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of FSHB protein] CTD PMID:32565124 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370 		JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions
increases expression		 ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [2-tert-butylhydroquinone results in increased expression of FTH1 mRNA]; PTEN protein affects the reaction [2-tert-butylhydroquinone results in increased expression of FTH1 mRNA]; wortmannin inhibits the reaction [2-tert-butylhydroquinone results in increased expression of FTH1 mRNA] CTD PMID:23829535 PMID:25003661 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424 		JBrowse link
G Ftl1 ferritin light chain 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of FTL1 mRNA CTD PMID:16014739 NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725
Ensembl chr 2:95,936,387...95,939,725 		JBrowse link
G Ftmt ferritin mitochondrial increases expression ISO 2-tert-butylhydroquinone results in increased expression of FTMT mRNA CTD PMID:15664434 NCBI chr18:45,758,874...45,760,123
Ensembl chr18:45,758,874...45,760,123 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [Streptozocin results in decreased expression of G6PD mRNA]; 2-tert-butylhydroquinone inhibits the reaction [Streptozocin results in decreased expression of G6PD protein] CTD PMID:35478295 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gabpa GA binding protein transcription factor subunit alpha affects localization ISO 2-tert-butylhydroquinone affects the localization of GABPA protein CTD PMID:16308312 NCBI chr11:23,888,586...23,917,612
Ensembl chr11:23,888,815...23,917,605 		JBrowse link
G Gata3 GATA binding protein 3 increases activity ISO [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased activity of GATA3 protein CTD PMID:22250088 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit affects expression
increases expression
increases activity
multiple interactions
decreases expression		 ISO
EXP		 2-tert-butylhydroquinone affects the expression of GCLC mRNA
2-tert-butylhydroquinone results in increased expression of GCLC mRNA
2-tert-butylhydroquinone results in increased activity of GCLC protein
2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of GCLC mRNA]; [2-tert-butylhydroquinone results in increased activity of GCLC protein] which results in increased abundance of Glutathione; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of GCLC mRNA; Isoniazid inhibits the reaction [2-tert-butylhydroquinone results in increased expression of GCLC mRNA]; NFE2L2 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of GCLC mRNA]
2-tert-butylhydroquinone results in decreased expression of GCLC mRNA		 CTD PMID:7955076 PMID:10978506 PMID:12007577 PMID:15946948 PMID:16014739 More... NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions
increases expression
decreases expression		 ISO
EXP		 NFE2L2 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of GCLM mRNA]
2-tert-butylhydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of GCLM mRNA]; [2,2',4,4'-tetrabromodiphenyl ether co-treated with 2-tert-butylhydroquinone] results in increased expression of GCLM mRNA
2-tert-butylhydroquinone results in decreased expression of GCLM mRNA		 CTD PMID:10978506 PMID:12007577 PMID:12081989 PMID:16014739 PMID:19183254 More... NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gpr87 G protein-coupled receptor 87 increases expression ISO 2-tert-butylhydroquinone results in increased expression of GPR87 mRNA CTD PMID:16014739 NCBI chr 2:143,439,741...143,440,901
Ensembl chr 2:143,439,735...143,458,190 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [Matrines results in increased expression of GPT protein] CTD PMID:37716422 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression
multiple interactions		 EXP 2-tert-butylhydroquinone results in increased expression of GPX1 protein
2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of GPX1 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of GPX1 protein]		 CTD PMID:28583816 PMID:32565124 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gpx4 glutathione peroxidase 4 increases expression
multiple interactions		 ISO
EXP		 2-tert-butylhydroquinone results in increased expression of GPX4 mRNA; 2-tert-butylhydroquinone results in increased expression of GPX4 protein
2-tert-butylhydroquinone inhibits the reaction [Matrines results in decreased expression of GPX4 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [Matrines results in decreased expression of GPX4 protein]
2-tert-butylhydroquinone inhibits the reaction [Emodin results in decreased expression of GPX4 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [Emodin results in decreased expression of GPX4 protein]		 CTD PMID:37393915 PMID:37716422 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of GRIA1 mRNA CTD PMID:16014739 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Gsr glutathione-disulfide reductase increases activity
multiple interactions		 ISO
EXP		 2-tert-butylhydroquinone results in increased activity of GSR protein
2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased activity of GSR protein]
2-tert-butylhydroquinone inhibits the reaction [sodium arsenite results in decreased activity of GSR protein]		 CTD PMID:12572858 PMID:24970285 PMID:32565124 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Gss glutathione synthetase increases expression
multiple interactions		 ISO
EXP		 2-tert-butylhydroquinone results in increased expression of GSS mRNA
[2-tert-butylhydroquinone co-treated with Cisplatin] results in increased expression of GSS mRNA		 CTD PMID:10978506 PMID:19183254 PMID:32428544 NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198 		JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression
multiple interactions		 EXP 2-tert-butylhydroquinone results in increased expression of GSTA2 mRNA; 2-tert-butylhydroquinone results in increased expression of GSTA2 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [2-tert-butylhydroquinone results in increased expression of GSTA2 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [2-tert-butylhydroquinone results in increased expression of GSTA2]; 2-tert-butylhydroquinone inhibits the reaction [oltipraz results in increased expression of GSTA2 mRNA]; 2-tert-butylhydroquinone results in increased expression of and results in increased activity of GSTA2 protein; [S-Nitroso-N-Acetylpenicillamine co-treated with 2-tert-butylhydroquinone] results in increased expression of GSTA2; Dexamethasone promotes the reaction [2-tert-butylhydroquinone results in increased expression of and results in increased activity of GSTA2 protein]; Dexamethasone promotes the reaction [2-tert-butylhydroquinone results in increased expression of GSTA2 mRNA]; N-acetylsphingosine inhibits the reaction [2-tert-butylhydroquinone results in increased expression of GSTA2 protein]		 CTD PMID:7587946 PMID:12242683 PMID:15155840 PMID:15319326 PMID:15357004 More... NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798 		JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression EXP 2-tert-butylhydroquinone results in increased expression of GSTA5 mRNA CTD PMID:20650352 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression
multiple interactions		 ISO 2-tert-butylhydroquinone results in increased expression of GSTM1 protein
[2-tert-butylhydroquinone co-treated with Cisplatin] results in increased expression of GSTM1 mRNA
2-tert-butylhydroquinone results in increased expression of GSTM1 mRNA		 CTD PMID:21443188 PMID:32428544 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression EXP
ISO		 2-tert-butylhydroquinone results in increased expression of GSTP1 protein
2-tert-butylhydroquinone results in increased expression of GSTP1 mRNA		 CTD PMID:12680784 PMID:15533597 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Gzmb granzyme B multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GZMB protein] CTD PMID:30171972 NCBI chr15:30,343,352...30,346,814
Ensembl chr15:30,173,603...30,346,814 		JBrowse link
G H2ax H2A.X variant histone multiple interactions
increases expression		 EXP
ISO		 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of H2AX protein]
2-tert-butylhydroquinone results in increased expression of H2AX protein
2-tert-butylhydroquinone inhibits the reaction [hydroquinone results in increased expression of H2AX protein]		 CTD PMID:28583816 PMID:35123993 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
Ensembl chr 4:44,671,786...44,673,239 		JBrowse link
G Hbg1 hemoglobin subunit gamma 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of HBG1 mRNA CTD PMID:21464371 NCBI chr 1:158,271,871...158,273,426
Ensembl chr 1:158,271,873...158,273,425 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 decreases expression EXP 2-tert-butylhydroquinone results in decreased expression of HES1 protein CTD PMID:29663635 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased secretion of HMGB1 protein] CTD PMID:23112101 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression		 ISO
EXP		 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]]; 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]; 2,2',4,4'-tetrabromodiphenyl ether promotes the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]; 2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]; 2-tert-butylhydroquinone promotes the reaction [sodium arsenite results in increased expression of HMOX1 protein]; [2-tert-butylhydroquinone co-treated with Buthionine Sulfoximine] results in increased expression of HMOX1 mRNA; brusatol inhibits the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 protein]; Calcium affects the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]; Calcium Chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]; Egtazic Acid inhibits the reaction [2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]]; Egtazic Acid inhibits the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]; ferric chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 protein]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]
2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in decreased expression of HMOX1 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in decreased expression of HMOX1 protein]; 2-tert-butylhydroquinone inhibits the reaction [Paraquat results in increased expression of HMOX1 protein]; 2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]; [2-tert-butylhydroquinone co-treated with Cisplatin] results in increased expression of HMOX1 mRNA; [2-tert-butylhydroquinone co-treated with CSF1 protein co-treated with TNFSF11 protein] results in increased expression of HMOX1 protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of HMOX1 mRNA; [TNFSF11 protein co-treated with 2-tert-butylhydroquinone] results in increased expression of HMOX1 protein; Acetylcysteine inhibits the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 protein]; Calcium Chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]; HMOX1 protein promotes the reaction [2-tert-butylhydroquinone inhibits the reaction [IFNG protein results in increased abundance of Nitrites]]; Isoniazid inhibits the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]
2-tert-butylhydroquinone inhibits the reaction [decamethrin results in increased expression of HMOX1 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [decamethrin results in increased expression of HMOX1 protein]; 2-tert-butylhydroquinone inhibits the reaction [Emodin results in decreased expression of HMOX1 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [Emodin results in decreased expression of HMOX1 protein]; 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of HMOX1 protein]; 2-tert-butylhydroquinone inhibits the reaction [Matrines results in decreased expression of HMOX1 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [Matrines results in decreased expression of HMOX1 protein]; 2-tert-butylhydroquinone promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of HMOX1 protein]; 2-tert-butylhydroquinone promotes the reaction [thallium nitrate results in increased expression of HMOX1 protein]; [2-tert-butylhydroquinone promotes the reaction [[NFE2L2 protein binds to HMOX1 promoter] which results in increased expression of HMOX1 mRNA]] which results in decreased susceptibility to Magnesium Chloride; FGF1 protein promotes the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 protein]; NFE2L2 gene mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 protein]
2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA; 2-tert-butylhydroquinone results in increased expression of HMOX1 protein		 CTD PMID:8612205 PMID:10473555 PMID:10874044 PMID:10975858 PMID:16014739 More... NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of HSD17B3 mRNA] CTD PMID:32565124 NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of HSD3B1 mRNA] CTD PMID:32565124 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Hsf1 heat shock transcription factor 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of HSF1 mRNA CTD PMID:30309986 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [pterostilbene results in increased expression of HSPA5 protein] CTD PMID:25341683 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [IL1B protein results in increased expression of ICAM1 protein]; 2-tert-butylhydroquinone inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] CTD PMID:35724838 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Ifng interferon gamma multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]; 2-tert-butylhydroquinone inhibits the reaction [IFNG protein results in increased abundance of Dinoprostone]; 2-tert-butylhydroquinone inhibits the reaction [IFNG protein results in increased abundance of Nitrites]; 2-tert-butylhydroquinone results in decreased expression of and results in decreased secretion of IFNG protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in decreased expression of and results in decreased secretion of IFNG protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in decreased expression of IFNG mRNA; HMOX1 protein promotes the reaction [2-tert-butylhydroquinone inhibits the reaction [IFNG protein results in increased abundance of Nitrites]]; NFE2L2 protein promotes the reaction [2-tert-butylhydroquinone inhibits the reaction [IFNG protein results in increased abundance of Nitrites]] CTD PMID:22250088 PMID:23942037 PMID:30171972 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [Sodium Chloride, Dietary results in increased expression of IKBKB protein modified form] CTD PMID:28844481 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250 		JBrowse link
G Il10 interleukin 10 multiple interactions
increases expression		 EXP 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of IL10 mRNA]
2-tert-butylhydroquinone results in increased expression of IL10 mRNA		 CTD PMID:32565124 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il12a interleukin 12A multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12A mRNA]; 2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL12B protein binds to IL12A protein]]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12A mRNA]]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL12B protein binds to IL12A protein]]] CTD PMID:25680285 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734 		JBrowse link
G Il12b interleukin 12B multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B mRNA]; 2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL12B protein binds to IL12A protein]]; 2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL23A protein binds to IL12B protein]]; 2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL12B protein]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B mRNA]]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL12B protein binds to IL12A protein]]] CTD PMID:25680285 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il13 interleukin 13 multiple interactions ISO [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of and results in increased secretion of IL13 protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of IL13 mRNA CTD PMID:22250088 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G Il16 interleukin 16 increases secretion ISO 2-tert-butylhydroquinone results in increased secretion of IL16 protein CTD PMID:30806763 NCBI chr 1:137,617,702...137,718,022
Ensembl chr 1:137,617,944...137,718,130 		JBrowse link
G Il17d interleukin 17D multiple interactions ISO 2-tert-butylhydroquinone promotes the reaction [Oxygen deficiency results in increased expression of IL17D protein] CTD PMID:34023435 NCBI chr15:31,671,337...31,688,833 JBrowse link
G Il1a interleukin 1 alpha increases expression ISO 2-tert-butylhydroquinone results in increased expression of IL1A mRNA CTD PMID:30806763 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO		 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of IL1B protein]; 2-tert-butylhydroquinone inhibits the reaction [Sodium Chloride, Dietary results in increased expression of and results in increased secretion of IL1B protein]
2-tert-butylhydroquinone inhibits the reaction [IL1B protein affects the localization of NFKBIA protein]; 2-tert-butylhydroquinone inhibits the reaction [IL1B protein affects the localization of RELA protein]; 2-tert-butylhydroquinone inhibits the reaction [IL1B protein results in increased expression of ICAM1 protein]; 2-tert-butylhydroquinone inhibits the reaction [IL1B protein results in increased expression of TNFAIP3 protein]		 CTD PMID:28583816 PMID:28844481 PMID:35724838 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il2 interleukin 2 decreases expression
multiple interactions		 ISO 2-tert-butylhydroquinone results in decreased expression of IL2 mRNA
2-tert-butylhydroquinone results in decreased expression of and results in decreased secretion of IL2 protein		 CTD PMID:23945499 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il23a interleukin 23 subunit alpha multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL23A protein binds to IL12B protein]] CTD PMID:25680285 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha decreases expression
multiple interactions		 ISO 2-tert-butylhydroquinone results in decreased expression of IL2RA mRNA; 2-tert-butylhydroquinone results in decreased expression of IL2RA protein
2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]		 CTD PMID:23945499 PMID:30171972 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697 		JBrowse link
G Il4 interleukin 4 multiple interactions ISO [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of and results in increased secretion of IL4 protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of IL4 mRNA
2-tert-butylhydroquinone promotes the reaction [Oxygen deficiency results in increased expression of IL4 protein]		 CTD PMID:22250088 PMID:34023435 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il5 interleukin 5 multiple interactions ISO [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of and results in increased secretion of IL5 protein CTD PMID:22250088 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO
EXP		 2-tert-butylhydroquinone inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased secretion of IL6 protein]; 2-tert-butylhydroquinone promotes the reaction [Oxygen deficiency results in increased expression of IL6 protein]
2-tert-butylhydroquinone inhibits the reaction [Sodium Chloride, Dietary results in increased expression of and results in increased secretion of IL6 protein]		 CTD PMID:25305463 PMID:28844481 PMID:34023435 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases phosphorylation		 ISO 2-tert-butylhydroquinone promotes the reaction [JUND protein binds to CYP2C9 promoter]; 2-tert-butylhydroquinone promotes the reaction [JUND protein modified form binds to CYP2C9 promoter]; JUND mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of CYP2C9 mRNA]; pyrazolanthrone inhibits the reaction [2-tert-butylhydroquinone results in increased phosphorylation of JUND protein] CTD PMID:24830941 NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799 		JBrowse link
G Kdr kinase insert domain receptor increases expression
multiple interactions		 ISO 2-tert-butylhydroquinone results in increased expression of KDR protein
[cyanoginosin LR co-treated with 2-tert-butylhydroquinone] results in increased expression of KDR protein		 CTD PMID:36206955 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions
increases expression
decreases response to substance
affects binding		 ISO
EXP		 2-tert-butylhydroquinone inhibits the reaction [KEAP1 protein binds to CUL3 protein]; 2-tert-butylhydroquinone inhibits the reaction [KEAP1 protein results in increased ubiquitination of NFE2L2 protein]; 2-tert-butylhydroquinone promotes the reaction [KEAP1 protein binds to NFE2L2 protein]; KEAP1 protein mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of and results in increased activity of NFE2L2 protein]; KEAP1 protein promotes the reaction [2-tert-butylhydroquinone results in increased expression of and results in increased activity of NFE2L2 protein]
2-tert-butylhydroquinone promotes the reaction [thallium nitrate results in decreased expression of KEAP1 protein]
2-tert-butylhydroquinone results in increased expression of KEAP1 protein
KEAP1 protein mutant form results in decreased susceptibility to 2-tert-butylhydroquinone
2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of KEAP1 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of KEAP1 protein]; 2-tert-butylhydroquinone inhibits the reaction [KEAP1 protein binds to CUL3 protein]; 2-tert-butylhydroquinone inhibits the reaction [KEAP1 protein binds to NFE2L2 protein]; 2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to KEAP1 protein]; [2-tert-butylhydroquinone co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] promotes the reaction [NFE2L2 protein binds to KEAP1 protein]; [2-tert-butylhydroquinone inhibits the reaction [KEAP1 protein binds to NFE2L2 protein]] which results in increased activity of NFE2L2 protein; Cadmium Chloride inhibits the reaction [2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to KEAP1 protein]]
2-tert-butylhydroquinone binds to KEAP1 protein		 CTD PMID:18417180 PMID:18512965 PMID:19033392 PMID:19808700 PMID:23589329 More... NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of LHB protein] CTD PMID:32565124 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972 		JBrowse link
G Mafg MAF bZIP transcription factor G decreases expression ISO 2-tert-butylhydroquinone results in decreased expression of MAFG mRNA CTD PMID:35724838 NCBI chr10:105,903,307...105,911,808
Ensembl chr10:105,903,237...105,912,026 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions		 ISO 2-tert-butylhydroquinone results in increased phosphorylation of MAPK1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [2-tert-butylhydroquinone results in increased phosphorylation of MAPK1 protein]; 2-tert-butylhydroquinone inhibits the reaction [arsenite results in increased phosphorylation of MAPK1 protein]		 CTD PMID:24830941 PMID:36343453 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation		 ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [2-tert-butylhydroquinone results in increased phosphorylation of MAPK3 protein]; 2-tert-butylhydroquinone inhibits the reaction [arsenite results in increased phosphorylation of MAPK3 protein] CTD PMID:24830941 PMID:36343453 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mchr1 melanin-concentrating hormone receptor 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of MCHR1 mRNA CTD PMID:16014739 NCBI chr 7:112,761,554...112,764,746
Ensembl chr 7:112,761,554...112,764,032 		JBrowse link
G Mfn2 mitofusin 2 multiple interactions
increases expression		 EXP 2-tert-butylhydroquinone inhibits the reaction [thallium nitrate results in decreased expression of MFN2 protein]
2-tert-butylhydroquinone results in increased expression of MFN2 protein		 CTD PMID:31726083 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Mt1 metallothionein 1 multiple interactions
increases expression		 ISO 2-tert-butylhydroquinone promotes the reaction [Cycloheximide results in increased expression of MT1 mRNA]; Cycloheximide promotes the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA]; Edetic Acid inhibits the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA]; Edetic Acid inhibits the reaction [zinc chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA]]; MTF1 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA]; zinc chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA]; Zinc deficiency inhibits the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA] CTD PMID:14998373 PMID:19276070 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049
Ensembl chr  X:10,826,032...10,827,049 		JBrowse link
G Mt2A metallothionein 2A increases expression ISO 2-tert-butylhydroquinone results in increased expression of MT2 mRNA CTD PMID:14998373 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Mtf1 metal-regulatory transcription factor 1 multiple interactions ISO MTF1 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA] CTD PMID:14998373 NCBI chr 5:137,062,319...137,107,136
Ensembl chr 5:137,062,376...137,107,136 		JBrowse link
G Mtrf1 mitochondrial translation release factor 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of MTRF1 mRNA CTD PMID:16014739 NCBI chr15:54,776,885...54,804,699
Ensembl chr15:54,776,937...54,804,704 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 multiple interactions ISO [TNFSF11 protein co-treated with CSF1 protein co-treated with 2-tert-butylhydroquinone] results in decreased expression of NFATC1 protein CTD PMID:23112101 NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028 		JBrowse link
G Nfe2l1 NFE2 like bZIP transcription factor 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of NFE2L1 protein CTD PMID:33838154 NCBI chr10:81,796,055...81,812,926
Ensembl chr10:81,800,366...81,832,318 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
affects binding
increases expression
increases stability
increases ubiquitination
decreases response to substance
increases activity
affects response to substance
affects localization
increases response to substance		 ISO
EXP		 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [2-tert-butylhydroquinone promotes the reaction [CREBBP protein binds to NFE2L2 protein]]; 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]]; 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein]; 2-tert-butylhydroquinone affects the localization of and results in increased activity of NFE2L2 protein; 2-tert-butylhydroquinone inhibits the reaction [Atorvastatin results in decreased expression of NFE2L2 protein]; 2-tert-butylhydroquinone inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of NFE2L2 protein]; 2-tert-butylhydroquinone inhibits the reaction [KEAP1 protein results in increased ubiquitination of NFE2L2 protein]; 2-tert-butylhydroquinone inhibits the reaction [Matrines results in decreased expression of NFE2L2 protein]; 2-tert-butylhydroquinone promotes the reaction [arsenite results in increased expression of NFE2L2 protein]; 2-tert-butylhydroquinone promotes the reaction [CREBBP protein binds to NFE2L2 protein]; 2-tert-butylhydroquinone promotes the reaction [hydroquinone results in increased expression of NFE2L2 protein]; 2-tert-butylhydroquinone promotes the reaction [KEAP1 protein binds to NFE2L2 protein]; 2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]; 2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to NQO1 promoter]; 2-tert-butylhydroquinone promotes the reaction [Oxygen deficiency results in increased expression of NFE2L2 protein]; 2-tert-butylhydroquinone promotes the reaction [pterostilbene results in increased phosphorylation of NFE2L2 protein]; 2-tert-butylhydroquinone results in increased expression of and affects the localization of NFE2L2 protein; 2-tert-butylhydroquinone results in increased expression of and results in increased activity of NFE2L2 protein; 2-tert-butylhydroquinone results in increased stability of and affects the localization of NFE2L2 protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in decreased susceptibility to arsenite; [2-tert-butylhydroquinone results in increased expression of NFE2L2 protein] which results in decreased susceptibility to Oxidopamine; brusatol inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NFE2L2 protein]; Egtazic Acid inhibits the reaction [2-tert-butylhydroquinone promotes the reaction [CREBBP protein binds to NFE2L2 protein]]; Egtazic Acid inhibits the reaction [2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]]; Egtazic Acid inhibits the reaction [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein]; ferric chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of NFE2L2 protein]; KEAP1 protein mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of and results in increased activity of NFE2L2 protein]; KEAP1 protein promotes the reaction [2-tert-butylhydroquinone results in increased expression of and results in increased activity of NFE2L2 protein]; Metformin inhibits the reaction [2-tert-butylhydroquinone results in increased stability of and affects the localization of NFE2L2 protein]; NFE2L2 affects the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12A mRNA]]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B mRNA]]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL12B protein binds to IL12A protein]]]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of EPHX1 exon]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; NFE2L2 mutant form inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with 2-tert-butylhydroquinone] results in increased expression of NQO1 mRNA]; NFE2L2 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of CES1 mRNA alternative form]
2-tert-butylhydroquinone binds to NFE2L2 protein
2-tert-butylhydroquinone results in increased expression of NFE2L2 mRNA; 2-tert-butylhydroquinone results in increased expression of NFE2L2 protein
2-tert-butylhydroquinone results in increased stability of NFE2L2 protein
2-tert-butylhydroquinone results in increased ubiquitination of NFE2L2 protein
NFE2L2 protein results in decreased susceptibility to 2-tert-butylhydroquinone
2-tert-butylhydroquinone affects the localization of and results in increased activity of NFE2L2 protein; 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of NFE2L2 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [Emodin results in decreased expression of and results in decreased localization of NFE2L2 protein]; 2-tert-butylhydroquinone inhibits the reaction [Emodin results in decreased expression of NFE2L2 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of NFE2L2 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of NFE2L2 protein]; 2-tert-butylhydroquinone inhibits the reaction [Matrines results in decreased expression of NFE2L2 protein]; 2-tert-butylhydroquinone inhibits the reaction [Sodium Chloride, Dietary results in decreased expression of NFE2L2 protein]; 2-tert-butylhydroquinone inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; 2-tert-butylhydroquinone promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of NFE2L2 protein]; 2-tert-butylhydroquinone results in increased expression of and results in increased localization of NFE2L2 protein; [2-tert-butylhydroquinone promotes the reaction [[NFE2L2 protein binds to HMOX1 promoter] which results in increased expression of HMOX1 mRNA]] which results in decreased susceptibility to Magnesium Chloride; [thallium nitrate co-treated with 2-tert-butylhydroquinone] results in increased expression of NFE2L2 protein; decamethrin inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NFE2L2 protein]; N-acetylsphingosine inhibits the reaction [2-tert-butylhydroquinone results in increased localization of NFE2L2 protein]; NFE2L2 gene mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 protein]
2-tert-butylhydroquinone results in increased activity of NFE2L2 protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased activity of GATA3 protein
2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in decreased expression of NFE2L2 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in decreased expression of NFE2L2 protein]; 2-tert-butylhydroquinone inhibits the reaction [Cisplatin affects the expression of and affects the localization of NFE2L2 protein]; 2-tert-butylhydroquinone inhibits the reaction [KEAP1 protein binds to NFE2L2 protein]; 2-tert-butylhydroquinone inhibits the reaction [Paraquat results in increased expression of NFE2L2 protein]; 2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to BCL2 promoter]; 2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]; 2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to KEAP1 protein]; 2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to NQO1 promoter]; 2-tert-butylhydroquinone results in increased expression of and affects the localization of NFE2L2 protein; [2-tert-butylhydroquinone co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] promotes the reaction [NFE2L2 protein binds to KEAP1 protein]; [2-tert-butylhydroquinone inhibits the reaction [KEAP1 protein binds to NFE2L2 protein]] which results in increased activity of NFE2L2 protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in decreased activity of TBX21 protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in decreased expression of and results in decreased secretion of IFNG protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in decreased expression of IFNG mRNA; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of and results in increased secretion of IL13 protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of and results in increased secretion of IL4 protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of and results in increased secretion of IL5 protein; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of GCLC mRNA; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of HMOX1 mRNA; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of IL13 mRNA; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of IL4 mRNA; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of NQO1 mRNA; [2-tert-butylhydroquinone results in increased stability of NFE2L2 protein] which results in decreased expression of BAX protein; [2-tert-butylhydroquinone results in increased stability of NFE2L2 protein] which results in increased expression of BCL2 protein; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 2-tert-butylhydroquinone] results in increased expression of NFE2L2 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [2-tert-butylhydroquinone results in increased ubiquitination of NFE2L2 protein]; Cadmium Chloride inhibits the reaction [2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to KEAP1 protein]]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of BCL2 mRNA]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; NFE2L2 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of GCLC mRNA]; NFE2L2 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of GCLM mRNA]; NFE2L2 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; NFE2L2 protein promotes the reaction [2-tert-butylhydroquinone inhibits the reaction [IFNG protein results in increased abundance of Nitrites]]; NFE2L2 protein promotes the reaction [2-tert-butylhydroquinone inhibits the reaction [Lipopolysaccharides results in increased abundance of Nitrites]]
NFE2L2 protein affects the susceptibility to 2-tert-butylhydroquinone
2-tert-butylhydroquinone affects the localization of NFE2L2 protein
NFE2L2 protein mutant form results in increased susceptibility to 2-tert-butylhydroquinone		 CTD PMID:10473555 PMID:10874044 PMID:12446695 PMID:14510636 PMID:14998373 More... NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP
ISO		 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased phosphorylation of NFKBIA protein]
2-tert-butylhydroquinone inhibits the reaction [IL1B protein affects the localization of NFKBIA protein]; 2-tert-butylhydroquinone inhibits the reaction [TNF protein affects the localization of NFKBIA protein]		 CTD PMID:28583816 PMID:35724838 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nkd1 NKD inhibitor of WNT signaling pathway 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of NKD1 mRNA CTD PMID:16014739 NCBI chr19:18,476,344...18,549,380
Ensembl chr19:18,476,344...18,549,380 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of NOS2 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of NOS2 protein] CTD PMID:32073640 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Notch1 notch receptor 1 decreases expression EXP 2-tert-butylhydroquinone results in decreased expression of NOTCH1 protein CTD PMID:29663635 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases activity
multiple interactions
increases expression
decreases expression		 ISO
EXP		 2-tert-butylhydroquinone results in increased activity of NQO1 protein
2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to NQO1 promoter]; 2-tert-butylhydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of NQO1 mRNA]; [lipopolysaccharide, E coli O55-B5 co-treated with 2-tert-butylhydroquinone] results in increased expression of NQO1 mRNA; [sodium arsenite co-treated with 2-tert-butylhydroquinone] results in increased expression of NQO1 mRNA; [sodium arsenite co-treated with 2-tert-butylhydroquinone] results in increased expression of NQO1 protein; Acetylcysteine inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; ferric chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 protein]; NFE2L2 affects the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; NFE2L2 mutant form inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with 2-tert-butylhydroquinone] results in increased expression of NQO1 mRNA]
2-tert-butylhydroquinone inhibits the reaction [Emodin results in decreased expression of NQO1 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [Emodin results in decreased expression of NQO1 protein]; 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of NQO1 protein]; 2-tert-butylhydroquinone inhibits the reaction [Matrines results in decreased expression of NQO1 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [Matrines results in decreased expression of NQO1 protein]; 2-tert-butylhydroquinone promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of NQO1 protein]; 2-tert-butylhydroquinone results in increased expression of and results in increased activity of NQO1 protein; [thallium nitrate co-treated with 2-tert-butylhydroquinone] results in increased expression of NQO1 protein; Dexamethasone inhibits the reaction [2-tert-butylhydroquinone results in increased expression of and results in increased activity of NQO1 protein]; Dexamethasone inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]
2-tert-butylhydroquinone results in increased expression of NQO1 mRNA; 2-tert-butylhydroquinone results in increased expression of NQO1 protein
2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to NQO1 promoter]; [2-tert-butylhydroquinone co-treated with Cisplatin] results in increased expression of NQO1 mRNA; [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of NQO1 mRNA; AG-879 inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; Cycloheximide inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; Isoniazid inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; NFE2L2 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; Paraquat inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; Zinc promotes the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]
2-tert-butylhydroquinone results in decreased expression of NQO1 mRNA		 CTD PMID:7587946 PMID:9029048 PMID:11163336 PMID:14510636 PMID:14998373 More... NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO 2-tert-butylhydroquinone binds to and results in increased activity of NR1I2 protein CTD PMID:33049310 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO 2-tert-butylhydroquinone binds to and results in decreased activity of NR1I3 protein alternative form CTD PMID:20869355 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of OLR1 mRNA CTD PMID:35724838 NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [Atorvastatin results in increased cleavage of PARP1 protein] CTD PMID:31423616 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of PCNA protein] CTD PMID:32565124 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pdgfb platelet derived growth factor subunit B increases expression ISO 2-tert-butylhydroquinone results in increased expression of PDGFB mRNA CTD PMID:35724838 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Pgd phosphogluconate dehydrogenase increases expression ISO 2-tert-butylhydroquinone results in increased expression of PGD mRNA CTD PMID:16014739 NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO 2-tert-butylhydroquinone binds to and results in increased activity of PPARG protein CTD PMID:33049310 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Prdx1 peroxiredoxin 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of PRDX1 mRNA CTD PMID:16014739 NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856 		JBrowse link
G Prf1 perforin 1 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of PRF1 protein] CTD PMID:30171972 NCBI chr20:29,246,202...29,251,712
Ensembl chr20:29,246,202...29,251,701 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha increases expression ISO 2-tert-butylhydroquinone results in increased expression of PRKACA mRNA CTD PMID:16014739 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430 		JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 decreases expression ISO 2-tert-butylhydroquinone results in decreased expression of PRKAG2 mRNA CTD PMID:35724838 NCBI chr 4:10,010,890...10,252,155
Ensembl chr 4:10,010,890...10,252,142 		JBrowse link
G Procr protein C receptor increases expression ISO 2-tert-butylhydroquinone results in increased expression of PROCR mRNA CTD PMID:16014739 NCBI chr 3:144,254,596...144,258,863
Ensembl chr 3:144,254,380...144,258,903 		JBrowse link
G Pten phosphatase and tensin homolog multiple interactions ISO PTEN protein affects the reaction [2-tert-butylhydroquinone results in increased expression of FTH1 mRNA] CTD PMID:23829535 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptgr1 prostaglandin reductase 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of PTGR1 mRNA CTD PMID:16014739 NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP
ISO		 2-tert-butylhydroquinone inhibits the reaction [Emodin results in increased expression of PTGS2 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of PTGS2 protein]
2-tert-butylhydroquinone inhibits the reaction [Matrines results in increased expression of PTGS2 mRNA]		 CTD PMID:28583816 PMID:37393915 PMID:37716422 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rel REL proto-oncogene, NF-kB subunit increases expression ISO 2-tert-butylhydroquinone results in increased expression of REL mRNA CTD PMID:16014739 NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
decreases phosphorylation		 EXP
ISO		 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in increased expression of RELA mRNA]; 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate affects the localization of RELA protein]; 2-tert-butylhydroquinone inhibits the reaction [Sodium Chloride, Dietary results in increased activity of RELA protein]
2-tert-butylhydroquinone results in decreased phosphorylation of RELA protein
2-tert-butylhydroquinone inhibits the reaction [arsenite results in increased phosphorylation of RELA protein]; 2-tert-butylhydroquinone inhibits the reaction [IL1B protein affects the localization of RELA protein]; 2-tert-butylhydroquinone inhibits the reaction [TNF protein affects the localization of RELA protein]
2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of RELA mRNA]; 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of RELA protein]; 2-tert-butylhydroquinone promotes the reaction [Particulate Matter results in decreased phosphorylation of RELA protein]		 CTD PMID:28583816 PMID:28844481 PMID:32073640 PMID:32565124 PMID:35724838 More... NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Rorc RAR-related orphan receptor C increases expression ISO 2-tert-butylhydroquinone results in increased expression of RORC mRNA CTD PMID:16014739 NCBI chr 2:182,009,707...182,034,910
Ensembl chr 2:182,009,286...182,034,907 		JBrowse link
G Slc3a2 solute carrier family 3 member 2 increases expression ISO 2-tert-butylhydroquinone results in increased expression of SLC3A2 mRNA CTD PMID:19183254 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931 		JBrowse link
G Slc40a1 solute carrier family 40 member 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of SLC40A1 mRNA CTD PMID:16014739 NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression
multiple interactions		 ISO 2-tert-butylhydroquinone results in increased expression of SLC7A11 mRNA
2-tert-butylhydroquinone inhibits the reaction [Matrines results in decreased expression of SLC7A11 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [Matrines results in decreased expression of SLC7A11 protein]
2-tert-butylhydroquinone results in increased expression of SLC7A11 mRNA; 2-tert-butylhydroquinone results in increased expression of SLC7A11 protein		 CTD PMID:19183254 PMID:37716422 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of SOD1 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [Sodium Chloride, Dietary results in decreased expression of SOD1 protein] CTD PMID:28844481 PMID:32565124 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 increases expression
multiple interactions		 ISO 2-tert-butylhydroquinone results in increased expression of SOD2 mRNA
[2-tert-butylhydroquinone co-treated with Cisplatin] results in increased expression of SOD2 mRNA
2-tert-butylhydroquinone inhibits the reaction [Atorvastatin affects the expression of SOD2 protein]
2-tert-butylhydroquinone results in increased expression of SOD2 protein		 CTD PMID:31423616 PMID:32428544 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sp1 Sp1 transcription factor increases expression ISO 2-tert-butylhydroquinone results in increased expression of SP1 protein CTD PMID:36206955 NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961 		JBrowse link
G Sqor sulfide quinone oxidoreductase increases expression ISO 2-tert-butylhydroquinone results in increased expression of SQOR mRNA CTD PMID:16014739 NCBI chr 3:109,841,225...109,886,724
Ensembl chr 3:109,841,250...109,960,778 		JBrowse link
G Sqstm1 sequestosome 1 increases expression
multiple interactions
decreases expression		 ISO
EXP		 2-tert-butylhydroquinone results in increased expression of SQSTM1 protein
[thallium nitrate co-treated with 2-tert-butylhydroquinone] results in increased expression of SQSTM1 protein
2-tert-butylhydroquinone results in decreased expression of SQSTM1 mRNA		 CTD PMID:23589329 PMID:31726083 PMID:35724838 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO [TNFSF11 protein co-treated with 2-tert-butylhydroquinone] results in decreased expression of SRC protein CTD PMID:23112101 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Srxn1 sulfiredoxin 1 increases expression
decreases expression		 ISO 2-tert-butylhydroquinone results in increased expression of SRXN1 mRNA
2-tert-butylhydroquinone results in increased expression of SRXN1 protein
2-tert-butylhydroquinone results in decreased expression of SRXN1 mRNA		 CTD PMID:16014739 PMID:22003191 PMID:35724838 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448 		JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions EXP 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of STAR mRNA]; 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in decreased expression of STAR protein] CTD PMID:32565124 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member increases expression ISO 2-tert-butylhydroquinone results in increased expression of TAP1 mRNA CTD PMID:35724838 NCBI chr20:4,656,262...4,666,634
Ensembl chr20:4,656,263...4,666,901 		JBrowse link
G Tbx21 T-box transcription factor 21 multiple interactions ISO [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in decreased activity of TBX21 protein CTD PMID:22250088 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831 		JBrowse link
G Tgfa transforming growth factor alpha multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [arsenite results in increased expression of and results in increased secretion of TGFA protein] CTD PMID:36343453 NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894 		JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO 2-tert-butylhydroquinone binds to and results in increased activity of THRB protein CTD PMID:33049310 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO		 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in increased expression of TNF mRNA]; 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of TNF protein]
2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of TNF mRNA]; 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of TNF protein]
2-tert-butylhydroquinone inhibits the reaction [TNF protein affects the localization of NFKBIA protein]; 2-tert-butylhydroquinone inhibits the reaction [TNF protein affects the localization of RELA protein]; 2-tert-butylhydroquinone inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; 2-tert-butylhydroquinone inhibits the reaction [TNF protein results in increased expression of TNFAIP3 protein]		 CTD PMID:28583816 PMID:32073640 PMID:32565124 PMID:35724838 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 multiple interactions
increases expression		 ISO 2-tert-butylhydroquinone inhibits the reaction [IL1B protein results in increased expression of TNFAIP3 protein]; 2-tert-butylhydroquinone inhibits the reaction [TNF protein results in increased expression of TNFAIP3 protein]
2-tert-butylhydroquinone results in increased expression of TNFAIP3 mRNA; 2-tert-butylhydroquinone results in increased expression of TNFAIP3 protein		 CTD PMID:35724838 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 increases expression ISO 2-tert-butylhydroquinone results in increased expression of TNFRSF9 mRNA CTD PMID:35724838 NCBI chr 5:161,381,662...161,408,003
Ensembl chr 5:161,381,662...161,408,000 		JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of AKT1 protein]; 2-tert-butylhydroquinone inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased secretion of HMGB1 protein]; [2-tert-butylhydroquinone co-treated with CSF1 protein co-treated with TNFSF11 protein] results in decreased expression of CSF1R protein; [2-tert-butylhydroquinone co-treated with CSF1 protein co-treated with TNFSF11 protein] results in increased expression of HMOX1 protein; [TNFSF11 protein co-treated with 2-tert-butylhydroquinone] results in decreased expression of CSF1R protein; [TNFSF11 protein co-treated with 2-tert-butylhydroquinone] results in decreased expression of SRC protein; [TNFSF11 protein co-treated with 2-tert-butylhydroquinone] results in increased expression of HMOX1 protein; [TNFSF11 protein co-treated with CSF1 protein co-treated with 2-tert-butylhydroquinone] results in decreased expression of CTSK protein; [TNFSF11 protein co-treated with CSF1 protein co-treated with 2-tert-butylhydroquinone] results in decreased expression of NFATC1 protein CTD PMID:23112101 NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Tob1 transducer of ErbB-2.1 decreases expression ISO 2-tert-butylhydroquinone results in decreased expression of TOB1 mRNA CTD PMID:16014739 NCBI chr10:79,163,093...79,165,131
Ensembl chr10:79,160,154...79,165,215 		JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression		 ISO
EXP		 2-tert-butylhydroquinone inhibits the reaction [hydroquinone results in increased expression of TP53 protein]
2-tert-butylhydroquinone results in increased expression of TP53 protein
2-tert-butylhydroquinone inhibits the reaction [Emodin results in increased expression of TP53 protein]		 CTD PMID:35123993 PMID:37393915 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Trib3 tribbles pseudokinase 3 decreases expression ISO 2-tert-butylhydroquinone results in decreased expression of TRIB3 mRNA CTD PMID:35724838 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497 		JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression
decreases expression		 ISO 2-tert-butylhydroquinone results in increased expression of TXNRD1 mRNA
2-tert-butylhydroquinone results in decreased expression of TXNRD1 mRNA		 CTD PMID:12949356 PMID:16014739 PMID:30806763 PMID:35724838 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression EXP 2-tert-butylhydroquinone results in increased expression of UGT1A1 mRNA CTD PMID:20650352 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 increases expression
multiple interactions
increases activity		 EXP
ISO		 2-tert-butylhydroquinone results in increased expression of UGT1A6 mRNA
AHR protein promotes the reaction [2-tert-butylhydroquinone results in increased expression of UGT1A6 mRNA]
2-tert-butylhydroquinone results in increased activity of UGT1A6 protein		 CTD PMID:10220484 PMID:12948865 NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases expression ISO 2-tert-butylhydroquinone results in increased expression of UGT1A9 mRNA CTD PMID:10220484 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 increases expression ISO 2-tert-butylhydroquinone results in increased expression of UGT2B7 mRNA CTD PMID:10220484 NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression ISO 2-tert-butylhydroquinone results in increased expression of VCAM1 mRNA CTD PMID:35724838 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958 		JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO 2-tert-butylhydroquinone results in decreased expression of VEGFA mRNA CTD PMID:35724838 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
6-decylubiquinone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions EXP 2,3-dimethoxy-5-methyl-6-decyl-1,4-benzoquinone inhibits the reaction [Diclofenac results in increased activity of CASP3 protein] CTD PMID:14599462 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Dhodh dihydroorotate dehydrogenase increases metabolic processing
multiple interactions		 EXP DHODH protein results in increased metabolism of 2,3-dimethoxy-5-methyl-6-decyl-1,4-benzoquinone
teriflunomide inhibits the reaction [DHODH protein results in increased metabolism of 2,3-dimethoxy-5-methyl-6-decyl-1,4-benzoquinone]		 CTD PMID:9802339 NCBI chr19:37,551,858...37,573,327
Ensembl chr19:37,558,177...37,591,654 		JBrowse link
Dephostatin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions ISO dephostatin promotes the reaction [[Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 protein] CTD PMID:14623285 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317 		JBrowse link
hydroquinone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A4galt alpha 1,4-galactosyltransferase decreases expression ISO hydroquinone results in decreased expression of A4GALT mRNA CTD PMID:31256213 NCBI chr 7:114,368,525...114,392,872
Ensembl chr 7:114,368,276...114,396,071 		JBrowse link
G Aatf apoptosis antagonizing transcription factor multiple interactions
increases expression
increases ADP-ribosylation		 ISO PARP1 protein affects the reaction [hydroquinone results in increased expression of AATF protein]
hydroquinone results in increased ADP-ribosylation of AATF protein		 CTD PMID:26822515 NCBI chr10:69,299,029...69,392,207
Ensembl chr10:69,299,037...69,392,201 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression ISO hydroquinone results in increased expression of ABCC3 mRNA CTD PMID:31256213 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Ace2 angiotensin converting enzyme 2 decreases expression ISO hydroquinone results in decreased expression of ACE2 mRNA CTD PMID:31256213 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Adam17 ADAM metallopeptidase domain 17 increases expression
multiple interactions		 ISO hydroquinone results in increased expression of ADAM17 protein
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in increased expression of ADAM17 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in increased expression of and results in increased stability of ADAM17 mRNA]; ADAM17 protein affects the reaction [hydroquinone results in increased secretion of TNF protein]; ATF2 protein affects the reaction [hydroquinone results in increased expression of ADAM17 mRNA]; ATF2 protein affects the reaction [hydroquinone results in increased expression of ADAM17 protein]; FOS protein affects the reaction [hydroquinone results in increased expression of ADAM17 mRNA]; FOS protein affects the reaction [hydroquinone results in increased expression of ADAM17 protein]; hydroquinone results in increased expression of and results in increased stability of ADAM17 mRNA; JUN protein affects the reaction [hydroquinone results in increased expression of ADAM17 mRNA]; JUN protein affects the reaction [hydroquinone results in increased expression of ADAM17 protein]; MIR122 mRNA affects the reaction [hydroquinone results in increased expression of ADAM17 protein]; MIR122 mRNA affects the reaction [hydroquinone results in increased expression of and results in increased stability of ADAM17 mRNA]; pyrazolanthrone inhibits the reaction [hydroquinone results in increased expression of ADAM17 protein]; pyrazolanthrone inhibits the reaction [hydroquinone results in increased expression of and results in increased stability of ADAM17 mRNA]		 CTD PMID:23791922 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639 		JBrowse link
G Adap2 ArfGAP with dual PH domains 2 increases expression ISO hydroquinone results in increased expression of ADAP2 mRNA CTD PMID:31256213 NCBI chr10:65,138,006...65,166,147
Ensembl chr10:65,138,020...65,165,604 		JBrowse link
G Adarb2 adenosine deaminase RNA specific B2 multiple interactions ISO hydroquinone inhibits the reaction [Estradiol results in increased expression of ADARB2 mRNA] CTD PMID:28704378 NCBI chr17:61,750,437...62,300,984
Ensembl chr17:61,756,067...62,300,831 		JBrowse link
G Adprh ADP-ribosylarginine hydrolase increases expression ISO hydroquinone results in increased expression of ADPRH mRNA CTD PMID:31256213 NCBI chr11:62,299,831...62,306,170
Ensembl chr11:62,299,793...62,306,931 		JBrowse link
G Adtrp androgen-dependent TFPI-regulating protein increases expression ISO hydroquinone results in increased expression of ADTRP mRNA CTD PMID:31256213 NCBI chr17:22,907,758...22,993,834
Ensembl chr17:22,930,740...22,993,826 		JBrowse link
G Aen apoptosis enhancing nuclease increases expression ISO hydroquinone results in increased expression of AEN mRNA CTD PMID:23416264 NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523 		JBrowse link
G Afap1 actin filament associated protein 1 decreases expression ISO hydroquinone results in decreased expression of AFAP1 mRNA CTD PMID:31256213 NCBI chr14:74,743,322...74,856,300
Ensembl chr14:74,743,320...74,856,263 		JBrowse link
G Aggf1 angiogenic factor with G patch and FHA domains 1 decreases expression ISO hydroquinone results in decreased expression of AGGF1 mRNA CTD PMID:31256213 NCBI chr 2:26,619,336...26,646,050
Ensembl chr 2:26,619,339...26,645,952 		JBrowse link
G Ahr aryl hydrocarbon receptor affects localization
multiple interactions
increases expression		 ISO
EXP		 hydroquinone affects the localization of AHR protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of and affects the localization of AHR protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of AHR protein]; hydroquinone results in increased expression of and affects the localization of AHR protein
alpha-naphthoflavone inhibits the reaction [hydroquinone results in increased expression of AHR protein]		 CTD PMID:15935814 PMID:29935983 PMID:35123993 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Aifm2 AIF family member 2 increases expression ISO hydroquinone results in increased expression of AIFM2 mRNA CTD PMID:31256213 NCBI chr20:29,654,283...29,679,239
Ensembl chr20:29,652,927...29,679,236 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 decreases expression ISO hydroquinone results in decreased expression of AKR1B10 mRNA CTD PMID:31256213 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases phosphorylation		 ISO hydroquinone inhibits the reaction [AKT1 protein results in increased phosphorylation of IRF3 protein]; hydroquinone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of AKT1 protein]; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of AKT1 protein]
4-phenylbutyric acid inhibits the reaction [hydroquinone results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in decreased phosphorylation of AKT1 protein]		 CTD PMID:17464197 PMID:28883758 PMID:37148176 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 multiple interactions ISO hydroquinone inhibits the reaction [AKT2 protein results in increased phosphorylation of IRF3 protein] CTD PMID:28883758 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817 		JBrowse link
G Akt3 AKT serine/threonine kinase 3 multiple interactions ISO hydroquinone inhibits the reaction [AKT3 protein results in increased phosphorylation of IRF3 protein] CTD PMID:28883758 NCBI chr13:88,943,708...89,225,831
Ensembl chr13:88,946,091...89,225,708 		JBrowse link
G Alb albumin multiple interactions ISO ALB protein binds to and affects the transport of hydroquinone CTD PMID:8831264 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 increases expression ISO hydroquinone results in increased expression of ALDH1L2 mRNA CTD PMID:31256213 NCBI chr 7:20,254,246...20,305,793
Ensembl chr 7:20,254,233...20,305,776 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member increases expression ISO hydroquinone results in increased expression of ALDH2 mRNA CTD PMID:15452088 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 increases expression ISO hydroquinone results in increased expression of ALDH3A1 mRNA CTD PMID:31256213 NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681 		JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type increases expression ISO hydroquinone results in increased expression of ALOX12 mRNA CTD PMID:31256213 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542 		JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type increases expression ISO hydroquinone results in increased expression of ALOX12B mRNA CTD PMID:31256213 NCBI chr10:53,863,060...53,874,938
Ensembl chr10:53,863,060...53,874,938 		JBrowse link
G Aloxe3 arachidonate epidermal lipoxygenase 3 increases expression ISO hydroquinone results in increased expression of ALOXE3 mRNA CTD PMID:31256213 NCBI chr10:53,830,219...53,854,328
Ensembl chr10:53,831,264...53,854,328 		JBrowse link
G Alpk1 alpha-kinase 1 increases expression ISO hydroquinone results in increased expression of ALPK1 mRNA CTD PMID:31256213 NCBI chr 2:216,126,939...216,247,180
Ensembl chr 2:216,128,825...216,247,157 		JBrowse link
G Ambp alpha-1-microglobulin/bikunin precursor increases expression ISO hydroquinone results in increased expression of AMBP mRNA CTD PMID:29221148 NCBI chr 5:76,568,094...76,578,416
Ensembl chr 5:76,568,094...76,578,331 		JBrowse link
G Ankdd1a ankyrin repeat and death domain containing 1A decreases expression ISO hydroquinone results in decreased expression of ANKDD1A mRNA CTD PMID:31256213 NCBI chr 8:66,017,571...66,043,738
Ensembl chr 8:66,017,773...66,042,651 		JBrowse link
G Anxa1 annexin A1 increases expression ISO hydroquinone results in increased expression of ANXA1 mRNA CTD PMID:31256213 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Anxa3 annexin A3 increases expression ISO hydroquinone results in increased expression of ANXA3 mRNA CTD PMID:31256213 NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617 		JBrowse link
G Apoe apolipoprotein E decreases expression
multiple interactions		 EXP hydroquinone results in decreased expression of APOE mRNA
[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in decreased expression of APOE mRNA; Acetylcysteine inhibits the reaction [[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in decreased expression of APOE mRNA]; Acetylcysteine inhibits the reaction [hydroquinone results in decreased expression of APOE mRNA]		 CTD PMID:33188856 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G App amyloid beta precursor protein multiple interactions ISO [KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of APP mRNA CTD PMID:37245849 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) decreases expression ISO hydroquinone results in decreased expression of AQP3 mRNA CTD PMID:31256213 NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720 		JBrowse link
G Arg1 arginase 1 increases expression ISO hydroquinone results in increased expression of ARG1 mRNA CTD PMID:31256213 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Arg2 arginase 2 increases expression ISO hydroquinone results in increased expression of ARG2 mRNA CTD PMID:31256213 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378 		JBrowse link
G Arhgap27 Rho GTPase activating protein 27 increases expression ISO hydroquinone results in increased expression of ARHGAP27 mRNA CTD PMID:31256213 NCBI chr10:88,280,470...88,313,225
Ensembl chr10:88,280,455...88,313,185 		JBrowse link
G Arhgap42 Rho GTPase activating protein 42 decreases expression ISO hydroquinone results in decreased expression of ARHGAP42 mRNA CTD PMID:31256213 NCBI chr 8:6,154,759...6,384,497
Ensembl chr 8:6,156,865...6,384,870 		JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha affects expression ISO hydroquinone affects the expression of ARHGDIA protein CTD PMID:17181942 NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023 		JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 increases expression ISO hydroquinone results in increased expression of ARHGEF2 mRNA CTD PMID:31256213 NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355 		JBrowse link
G Arhgef26 Rho guanine nucleotide exchange factor 26 decreases expression ISO hydroquinone results in decreased expression of ARHGEF26 mRNA CTD PMID:31256213 NCBI chr 2:146,740,336...146,850,918
Ensembl chr 2:146,739,631...146,850,819 		JBrowse link
G Arl3 ARF like GTPase 3 decreases expression ISO hydroquinone results in decreased expression of ARL3 mRNA CTD PMID:31256213 NCBI chr 1:245,400,659...245,446,673
Ensembl chr 1:245,400,550...245,446,820 		JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator increases expression
multiple interactions		 ISO hydroquinone results in increased expression of ARNT protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of ARNT protein]		 CTD PMID:35123993 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO hydroquinone results in increased expression of ASNS mRNA CTD PMID:31256213 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423 		JBrowse link
G Asprv1 aspartic peptidase, retroviral-like 1 increases expression ISO hydroquinone results in increased expression of ASPRV1 mRNA CTD PMID:31256213 NCBI chr 4:119,077,415...119,078,887
Ensembl chr 4:119,077,356...119,078,379 		JBrowse link
G Atf2 activating transcription factor 2 increases phosphorylation
multiple interactions		 ISO hydroquinone results in increased phosphorylation of ATF2 protein
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in increased phosphorylation of ATF2 protein]; ATF2 protein affects the reaction [hydroquinone results in decreased expression of MIR122 mRNA]; ATF2 protein affects the reaction [hydroquinone results in increased expression of ADAM17 mRNA]; ATF2 protein affects the reaction [hydroquinone results in increased expression of ADAM17 protein]; ATF2 protein affects the reaction [hydroquinone results in increased expression of PPP2CA protein]; ATF2 protein affects the reaction [hydroquinone results in increased expression of TNF protein]; hydroquinone promotes the reaction [ATF2 protein binds to MIR122 promoter]; hydroquinone promotes the reaction [ATF2 protein binds to PPP2CA promoter]; pyrazolanthrone inhibits the reaction [hydroquinone results in increased phosphorylation of ATF2 protein]		 CTD PMID:23288922 PMID:23791922 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236 		JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO hydroquinone results in increased expression of ATF3 mRNA CTD PMID:31256213 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO hydroquinone results in increased expression of ATF4 mRNA; hydroquinone results in increased expression of ATF4 protein CTD PMID:15452088 PMID:24053669 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Atf6 activating transcription factor 6 multiple interactions
decreases expression
increases expression		 ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of ATF6 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in decreased expression of ATF6 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of ATF6 protein]; [Sirolimus co-treated with hydroquinone] results in decreased expression of ATF6 protein; Acetylcysteine inhibits the reaction [hydroquinone results in decreased expression of ATF6 protein]; ATF6 protein affects the reaction [hydroquinone results in decreased phosphorylation of MTOR protein]; ATF6 protein affects the reaction [hydroquinone results in increased expression of BAX protein]; ATF6 protein affects the reaction [hydroquinone results in increased lipidation of MAP1LC3B protein]
hydroquinone results in decreased expression of ATF6 mRNA; hydroquinone results in decreased expression of ATF6 protein		 CTD PMID:36646296 PMID:37148176 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177 		JBrowse link
G Atg12 autophagy related 12 increases expression ISO hydroquinone results in increased expression of ATG12 protein CTD PMID:37148176 NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418 		JBrowse link
G Atg5 autophagy related 5 multiple interactions
increases expression		 ISO PARP1 protein promotes the reaction [hydroquinone results in increased expression of ATG5 mRNA]; SIRT1 protein inhibits the reaction [hydroquinone results in increased expression of ATG5 mRNA] CTD PMID:28263894 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209 		JBrowse link
G Atg7 autophagy related 7 increases expression ISO hydroquinone results in increased expression of ATG7 protein CTD PMID:35302183 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
G Atp2c2 ATPase secretory pathway Ca2+ transporting 2 increases expression ISO hydroquinone results in increased expression of ATP2C2 mRNA CTD PMID:31256213 NCBI chr19:47,754,120...47,811,369
Ensembl chr19:47,754,120...47,811,368 		JBrowse link
G Atp6v1c2 ATPase H+ transporting V1 subunit C2 increases expression ISO hydroquinone results in increased expression of ATP6V1C2 mRNA CTD PMID:31256213 NCBI chr 6:40,080,545...40,144,199
Ensembl chr 6:40,080,547...40,120,028 		JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc-binding increases expression ISO hydroquinone results in increased expression of AZGP1 mRNA CTD PMID:31256213 NCBI chr12:16,930,990...16,939,333
Ensembl chr12:16,931,024...16,939,091 		JBrowse link
G Bach1 BTB domain and CNC homolog 1 multiple interactions
decreases expression
affects localization		 ISO [ferric chloride results in increased oxidation of hydroquinone] promotes the reaction [hydroquinone analog binds to BACH1 protein]; hydroquinone promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of BACH1 protein]
hydroquinone results in decreased expression of BACH1 protein
hydroquinone affects the localization of BACH1 protein		 CTD PMID:23290930 PMID:28645578 NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447 		JBrowse link
G Bad BCL2-associated agonist of cell death decreases expression ISO hydroquinone results in decreased expression of BAD mRNA CTD PMID:15452088 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bag1 BAG cochaperone 1 decreases expression ISO hydroquinone results in decreased expression of BAG1 mRNA CTD PMID:31256213 NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075 		JBrowse link
G Bambi BMP and activin membrane-bound inhibitor increases expression ISO hydroquinone results in increased expression of BAMBI mRNA CTD PMID:31256213 NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
increases expression
multiple interactions		 ISO hydroquinone results in decreased expression of BAX protein
hydroquinone results in increased expression of BAX protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of BAX protein]; 4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine inhibits the reaction [hydroquinone results in increased expression of BAX protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of BAX protein]; [ABT-737 co-treated with hydroquinone] results in increased expression of BAX protein; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of BAX protein]; ATF6 protein affects the reaction [hydroquinone results in increased expression of BAX protein]; CDKN2A protein affects the reaction [hydroquinone results in decreased expression of BAX protein]; PARP1 protein inhibits the reaction [hydroquinone results in decreased expression of BAX protein]; Sirolimus promotes the reaction [hydroquinone results in increased expression of BAX protein]		 CTD PMID:27515134 PMID:27606422 PMID:28843007 PMID:33771647 PMID:33932074 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO hydroquinone results in increased expression of BBC3 mRNA CTD PMID:23416264 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Bcl11a BCL11 transcription factor A decreases expression ISO hydroquinone results in decreased expression of BCL11A mRNA CTD PMID:31256213 NCBI chr14:98,029,018...98,124,181
Ensembl chr14:98,030,461...98,124,180 		JBrowse link
G Bcl11b BCL11 transcription factor B decreases expression ISO hydroquinone results in decreased expression of BCL11B mRNA CTD PMID:31256213 NCBI chr 6:126,834,531...126,927,720
Ensembl chr 6:126,834,531...126,928,224 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
increases expression		 ISO [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of BCL2 protein; [PARP1 protein co-treated with hydroquinone] results in increased expression of BCL2 protein; CDKN2A protein affects the reaction [hydroquinone results in increased expression of BCL2 protein]; PARP1 protein affects the reaction [hydroquinone results in decreased expression of BCL2 protein]
hydroquinone results in decreased expression of BCL2 mRNA; hydroquinone results in decreased expression of BCL2 protein
hydroquinone promotes the reaction [XBP1 protein affects the expression of BCL2 mRNA]; XBP1 protein affects the reaction [hydroquinone results in decreased expression of BCL2 mRNA]
hydroquinone results in increased expression of BCL2 mRNA; hydroquinone results in increased expression of BCL2 protein		 CTD PMID:23288922 PMID:24053669 PMID:27515134 PMID:27606422 PMID:28444915 More... NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression
increases expression		 ISO hydroquinone results in decreased expression of BCL2L1 protein
hydroquinone results in increased expression of BCL2L1 protein		 CTD PMID:23288922 PMID:35561756 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Bdh2 3-hydroxybutyrate dehydrogenase 2 decreases expression ISO hydroquinone results in decreased expression of BDH2 mRNA CTD PMID:31256213 NCBI chr 2:223,702,410...223,723,076
Ensembl chr 2:223,702,412...223,723,072 		JBrowse link
G Becn1 beclin 1 increases expression
multiple interactions		 ISO hydroquinone results in increased expression of BECN1 mRNA; hydroquinone results in increased expression of BECN1 protein
PARP1 protein promotes the reaction [hydroquinone results in increased expression of BECN1 mRNA]; SIRT1 protein inhibits the reaction [hydroquinone results in increased expression of BECN1 mRNA]		 CTD PMID:28263894 PMID:35302183 PMID:37148176 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Bid BH3 interacting domain death agonist increases cleavage
multiple interactions		 ISO hydroquinone results in increased cleavage of BID protein
FADD protein affects the reaction [hydroquinone results in increased cleavage of BID protein]		 CTD PMID:23288922 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression
decreases expression		 ISO hydroquinone results in increased expression of BIRC3 mRNA
hydroquinone results in decreased expression of BIRC3 mRNA		 CTD PMID:15452088 PMID:31256213 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression
multiple interactions		 ISO hydroquinone results in decreased expression of BIRC5 protein
Lithium Chloride inhibits the reaction [hydroquinone results in decreased expression of BIRC5 protein]		 CTD PMID:28886972 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Bnip3 BCL2 interacting protein 3 decreases expression ISO hydroquinone results in decreased expression of BNIP3 mRNA CTD PMID:15452088 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G Bora bora, aurora kinase A activator decreases expression ISO hydroquinone results in decreased expression of BORA mRNA CTD PMID:23416264 NCBI chr15:75,797,624...75,835,599
Ensembl chr15:75,797,891...75,821,322 		JBrowse link
G Bpifc BPI fold containing family C increases expression ISO hydroquinone results in increased expression of BPIFC mRNA CTD PMID:31256213 NCBI chr 7:17,848,787...17,905,993
Ensembl chr 7:17,861,007...17,905,919 		JBrowse link
G Brca1 BRCA1, DNA repair associated increases expression ISO hydroquinone results in increased expression of BRCA1 protein CTD PMID:29421518 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304 		JBrowse link
G Bst2 bone marrow stromal cell antigen 2 decreases expression ISO hydroquinone results in decreased expression of BST2 mRNA CTD PMID:31256213 NCBI chr16:18,216,605...18,220,979
Ensembl chr16:18,217,407...18,220,979 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO hydroquinone results in increased expression of BTG2 mRNA CTD PMID:23416264 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628 		JBrowse link
G Btrc beta-transducin repeat containing E3 ubiquitin protein ligase multiple interactions ISO 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of BTRC protein]; [WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of BTRC mRNA; [WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of BTRC protein; BTRC protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of PMAIP1 protein]; BTRC protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of SP1 protein]; Chloroquine inhibits the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of BTRC mRNA]; Dactinomycin promotes the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of BTRC mRNA] CTD PMID:35561756 NCBI chr 1:244,210,299...244,380,126
Ensembl chr 1:244,210,314...244,376,721 		JBrowse link
G Bub3 BUB3 mitotic checkpoint protein decreases expression ISO hydroquinone results in decreased expression of BUB3 mRNA CTD PMID:31256213 NCBI chr 1:186,330,358...186,340,969
Ensembl chr 1:186,327,931...186,395,036 		JBrowse link
G C19h16orf74 similar to human chromosome 16 open reading frame 74 increases expression ISO hydroquinone results in increased expression of C16ORF74 mRNA CTD PMID:31256213 NCBI chr19:48,660,288...48,686,287
Ensembl chr19:48,660,288...48,686,349 		JBrowse link
G C3h15orf48 similar to human chromosome 15 open reading frame 48 increases expression ISO hydroquinone results in increased expression of C15ORF48 mRNA CTD PMID:31256213 NCBI chr 3:109,719,952...109,723,505
Ensembl chr 3:109,719,897...109,724,006
Ensembl chr 3:109,719,897...109,724,006 		JBrowse link
G Calb2 calbindin 2 increases expression ISO hydroquinone results in increased expression of CALB2 mRNA CTD PMID:31256213 NCBI chr19:38,114,435...38,141,438
Ensembl chr19:38,114,424...38,141,438 		JBrowse link
G Calcb calcitonin-related polypeptide, beta increases expression ISO hydroquinone results in increased expression of CALCB mRNA CTD PMID:31256213 NCBI chr 1:168,965,383...168,970,259
Ensembl chr 1:168,966,465...168,970,125 		JBrowse link
G Calhm6 calcium homeostasis modulator family member 6 decreases expression ISO hydroquinone results in decreased expression of CALHM6 mRNA CTD PMID:31256213 NCBI chr20:26,095,591...26,097,336
Ensembl chr20:26,095,592...26,097,278 		JBrowse link
G Calml3 calmodulin-like 3 decreases expression ISO hydroquinone results in decreased expression of CALML3 mRNA CTD PMID:31256213 NCBI chr17:66,419,844...66,423,083
Ensembl chr17:66,419,882...66,423,175 		JBrowse link
G Capn2 calpain 2 decreases activity ISO hydroquinone results in decreased activity of CAPN2 protein CTD PMID:9118890 NCBI chr13:94,150,244...94,200,969
Ensembl chr13:94,150,240...94,200,969 		JBrowse link
G Car3 carbonic anhydrase 3 decreases expression ISO hydroquinone results in decreased expression of CA3 mRNA CTD PMID:31256213 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280 		JBrowse link
G Car9 carbonic anhydrase 9 decreases expression ISO hydroquinone results in decreased expression of CA9 mRNA CTD PMID:31256213 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838 		JBrowse link
G Casp1 caspase 1 increases cleavage
multiple interactions		 ISO hydroquinone results in increased cleavage of CASP1 protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased cleavage of CASP1 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased cleavage of CASP1 protein]		 CTD PMID:36646296 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp12 caspase 12 multiple interactions ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of CASP12 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of CASP12 protein] CTD PMID:36646296 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
increases degradation
increases cleavage
increases expression
decreases activity
decreases expression		 ISO
EXP		 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased cleavage of CASP3 protein]; 2-tert-butylhydroquinone inhibits the reaction [hydroquinone results in increased cleavage of CASP3 protein]; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of and affects the activity of CASP3 protein; Acetylcysteine inhibits the reaction [hydroquinone results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased cleavage of CASP3 protein]; FADD protein affects the reaction [hydroquinone results in increased cleavage of CASP3 protein]; hydroquinone results in decreased expression of and results in increased cleavage of CASP3 protein; IGF1 protein inhibits the reaction [hydroquinone results in increased expression of CASP3 protein modified form]; Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of CASP3 protein modified form]; NOX4 protein promotes the reaction [hydroquinone results in increased degradation of CASP3 protein]; Okadaic Acid inhibits the reaction [hydroquinone results in increased cleavage of CASP3 protein]; PARP1 protein affects the reaction [hydroquinone results in increased cleavage of CASP3 protein]
hydroquinone results in decreased activity of CASP3 protein
[hydroquinone results in increased abundance of Reactive Oxygen Species] which results in decreased activity of CASP3 protein
hydroquinone results in decreased expression of CASP3 mRNA; hydroquinone results in decreased expression of CASP3 protein		 CTD PMID:15337166 PMID:15452088 PMID:15777082 PMID:15816534 PMID:20946948 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp4 caspase 4 increases cleavage ISO hydroquinone results in increased cleavage of CASP4 protein CTD PMID:24053669 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
G Casp6 caspase 6 decreases expression ISO hydroquinone results in decreased expression of CASP6 mRNA CTD PMID:15452088 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502 		JBrowse link
G Casp7 caspase 7 increases cleavage
increases expression
decreases activity
multiple interactions		 ISO hydroquinone results in increased cleavage of CASP7 protein
hydroquinone results in increased expression of CASP7 protein modified form
hydroquinone results in decreased activity of CASP7 protein
Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of CASP7 protein modified form]; WRN protein inhibits the reaction [hydroquinone results in increased cleavage of CASP7 protein]		 CTD PMID:19064679 PMID:22960397 PMID:28886972 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Casp8 caspase 8 multiple interactions
increases cleavage
increases expression
increases activity		 ISO FADD protein affects the reaction [hydroquinone results in increased cleavage of CASP8 protein]; MPO protein affects the reaction [hydroquinone results in increased cleavage of CASP8 protein]; Okadaic Acid inhibits the reaction [hydroquinone results in increased cleavage of CASP8 protein]
hydroquinone results in increased expression of CASP8 protein
hydroquinone results in increased activity of CASP8 protein		 CTD PMID:15777082 PMID:23288922 PMID:23776099 PMID:27606422 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 decreases expression
increases activity
increases expression
multiple interactions
increases cleavage		 ISO
EXP		 hydroquinone results in decreased expression of CASP9 mRNA; hydroquinone results in decreased expression of CASP9 protein
hydroquinone results in increased activity of CASP9 protein
hydroquinone results in increased expression of CASP9 protein
Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of CASP9 protein modified form]; Okadaic Acid inhibits the reaction [hydroquinone results in increased cleavage of CASP9 protein]		 CTD PMID:15452088 PMID:15777082 PMID:15816534 PMID:20946948 PMID:22302391 More... NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase decreases response to substance
decreases activity		 ISO
EXP		 CAT protein results in decreased susceptibility to hydroquinone
hydroquinone results in decreased activity of CAT protein		 CTD PMID:10193577 PMID:26056850 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cavin2 caveolae associated protein 2 decreases expression ISO hydroquinone results in decreased expression of CAVIN2 mRNA CTD PMID:31256213 NCBI chr 9:50,302,079...50,314,096
Ensembl chr 9:50,301,206...50,314,147 		JBrowse link
G Cbs cystathionine beta synthase increases expression ISO hydroquinone results in increased expression of CBS mRNA CTD PMID:31256213 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764 		JBrowse link
G Ccdc127 coiled-coil domain containing 127 decreases expression ISO hydroquinone results in decreased expression of CCDC127 mRNA CTD PMID:31256213 NCBI chr 1:28,928,420...28,935,885
Ensembl chr 1:28,928,325...28,935,893 		JBrowse link
G Ccdc163 coiled-coil domain containing 163 decreases expression ISO hydroquinone results in decreased expression of CCDC163 mRNA CTD PMID:31256213 NCBI chr 5:130,172,014...130,178,934
Ensembl chr 5:130,172,774...130,178,929 		JBrowse link
G Ccdc8 coiled-coil domain containing 8 decreases expression ISO hydroquinone results in decreased expression of CCDC8 mRNA CTD PMID:31256213 NCBI chr 1:77,679,521...77,682,849
Ensembl chr 1:77,679,218...77,683,090 		JBrowse link
G Ccdc88c coiled-coil domain containing 88C decreases expression ISO hydroquinone results in decreased expression of CCDC88C mRNA CTD PMID:31256213 NCBI chr 6:120,169,752...120,289,459
Ensembl chr 6:120,169,738...120,289,555 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases expression ISO hydroquinone results in increased expression of CCL11 protein CTD PMID:17572062 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases secretion
decreases expression
multiple interactions
increases secretion
increases expression		 ISO hydroquinone results in decreased secretion of CCL2 protein
hydroquinone results in decreased expression of CCL2 mRNA
hydroquinone inhibits the reaction [[IFNG protein co-treated with lipopolysaccharide, E. coli O26-B6] results in increased secretion of CCL2 protein]; hydroquinone inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CCL2 mRNA]; hydroquinone inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CCL2 protein]; hydroquinone inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of CCL2 protein]
hydroquinone results in increased secretion of CCL2 protein
hydroquinone results in increased expression of CCL2 protein		 CTD PMID:17572062 PMID:20946948 PMID:22302391 PMID:22465845 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression ISO hydroquinone results in increased expression of CCL3 protein CTD PMID:17572062 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression ISO hydroquinone results in increased expression of CCL4 protein CTD PMID:17572062 PMID:18353026 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO hydroquinone results in increased expression of CCL5 protein CTD PMID:17572062 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccn1 cellular communication network factor 1 affects expression ISO hydroquinone affects the expression of CCN1 mRNA CTD PMID:15452088 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484 		JBrowse link
G Ccn2 cellular communication network factor 2 increases expression ISO hydroquinone results in increased expression of CCN2 mRNA CTD PMID:31256213 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Ccna1 cyclin A1 increases expression ISO hydroquinone results in increased expression of CCNA1 mRNA CTD PMID:31256213 NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions
increases expression
decreases expression		 ISO Lithium Chloride inhibits the reaction [hydroquinone results in decreased expression of CCND1 protein]; MIR7-2 promotes the reaction [hydroquinone results in increased expression of CCND1 protein]
hydroquinone results in increased expression of CCND1 mRNA; hydroquinone results in increased expression of CCND1 protein		 CTD PMID:28886972 PMID:33932074 PMID:37951342 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccne1 cyclin E1 increases expression
multiple interactions		 ISO hydroquinone results in increased expression of CCNE1 protein
MIR7-2 promotes the reaction [hydroquinone results in increased expression of CCNE1 protein]		 CTD PMID:37951342 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101 		JBrowse link
G Ccne2 cyclin E2 increases expression ISO hydroquinone results in increased expression of CCNE2 mRNA CTD PMID:23416264 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632 		JBrowse link
G Ccnf cyclin F decreases expression ISO hydroquinone results in decreased expression of CCNF mRNA CTD PMID:23416264 NCBI chr10:13,253,073...13,279,140
Ensembl chr10:13,253,380...13,279,101 		JBrowse link
G Ccsap centriole, cilia and spindle-associated protein decreases expression ISO hydroquinone results in decreased expression of CCSAP mRNA CTD PMID:31256213 NCBI chr19:51,824,954...51,843,469
Ensembl chr19:51,826,994...51,842,753 		JBrowse link
G Cd69 Cd69 molecule multiple interactions ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of CD69 protein] CTD PMID:20054000 NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542 		JBrowse link
G Cd80 Cd80 molecule multiple interactions ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of CD80 protein] CTD PMID:19148301 NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030 		JBrowse link
G Cd86 CD86 molecule increases expression
multiple interactions		 ISO hydroquinone results in increased expression of CD86 protein
hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of CD86 protein]		 CTD PMID:19148301 PMID:19665512 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Cdca2 cell division cycle associated 2 decreases expression ISO hydroquinone results in decreased expression of CDCA2 mRNA CTD PMID:23416264 NCBI chr15:41,895,946...41,942,226
Ensembl chr15:41,895,901...41,941,611 		JBrowse link
G Cdca7 cell division cycle associated 7 decreases expression ISO hydroquinone results in decreased expression of CDCA7 mRNA CTD PMID:31256213 NCBI chr 3:57,322,718...57,333,353
Ensembl chr 3:57,322,708...57,333,353 		JBrowse link
G Cdh26 cadherin 26 decreases expression ISO hydroquinone results in decreased expression of CDH26 mRNA CTD PMID:31256213 NCBI chr 3:165,520,523...165,573,191
Ensembl chr 3:165,520,439...165,572,149 		JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions
increases expression		 ISO MIR7-2 promotes the reaction [hydroquinone results in increased expression of CDK2 protein] CTD PMID:37951342 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 multiple interactions
increases expression		 ISO MIR7-2 promotes the reaction [hydroquinone results in increased expression of CDK4 protein] CTD PMID:37951342 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions		 ISO hydroquinone results in increased expression of CDKN1A mRNA; hydroquinone results in increased expression of CDKN1A protein
SIRT1 protein affects the reaction [hydroquinone results in increased expression of CDKN1A protein]		 CTD PMID:23416264 PMID:27515134 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C decreases expression ISO hydroquinone results in decreased expression of CDKN1C mRNA CTD PMID:31256213 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions
decreases expression		 ISO CDKN2A protein affects the reaction [hydroquinone results in decreased expression of BAX protein]; CDKN2A protein affects the reaction [hydroquinone results in decreased expression of RB1 protein]; CDKN2A protein affects the reaction [hydroquinone results in decreased expression of TP53 protein]; CDKN2A protein affects the reaction [hydroquinone results in increased expression of BCL2 protein]; CDKN2A protein affects the reaction [hydroquinone results in increased expression of MMP9 mRNA]; CDKN2A protein affects the reaction [hydroquinone results in increased expression of MMP9 protein]; PARP1 protein inhibits the reaction [hydroquinone results in decreased expression of CDKN2A protein]
hydroquinone results in decreased expression of CDKN2A mRNA; hydroquinone results in decreased expression of CDKN2A protein		 CTD PMID:33771647 PMID:33932074 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Cdsn corneodesmosin increases expression ISO hydroquinone results in increased expression of CDSN mRNA CTD PMID:31256213 NCBI chr20:3,179,432...3,184,252
Ensembl chr20:3,179,438...3,184,250 		JBrowse link
G Cemip cell migration inducing hyaluronidase 1 increases expression ISO hydroquinone results in increased expression of CEMIP mRNA CTD PMID:31256213 NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415 		JBrowse link
G Cenpa centromere protein A decreases expression ISO hydroquinone results in decreased expression of CENPA mRNA CTD PMID:23416264 NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675 		JBrowse link
G Cep15 centrosomal protein 15 decreases expression ISO hydroquinone results in decreased expression of CEP15 mRNA CTD PMID:31256213 NCBI chr15:12,815,159...12,835,115
Ensembl chr15:12,818,385...12,833,838 		JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO hydroquinone results in increased expression of CES1 mRNA CTD PMID:31256213 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Cfap44 cilia and flagella associated protein 44 decreases expression ISO hydroquinone results in decreased expression of CFAP44 mRNA CTD PMID:31256213 NCBI chr11:56,199,772...56,283,964
Ensembl chr11:56,201,049...56,283,986 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression ISO hydroquinone results in increased expression of CFLAR mRNA CTD PMID:31256213 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034 		JBrowse link
G Ch25h cholesterol 25-hydroxylase increases expression ISO hydroquinone results in increased expression of CH25H mRNA CTD PMID:31256213 NCBI chr 1:232,014,877...232,016,195
Ensembl chr 1:232,014,880...232,016,195 		JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 increases expression
decreases expression		 ISO hydroquinone results in increased expression of CHAC1 mRNA
hydroquinone results in decreased expression of CHAC1 mRNA		 CTD PMID:29221148 PMID:31256213 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526 		JBrowse link
G Chp2 calcineurin-like EF hand protein 2 decreases expression ISO hydroquinone results in decreased expression of CHP2 mRNA CTD PMID:31256213 NCBI chr 1:176,757,945...176,772,443
Ensembl chr 1:176,757,876...176,772,139 		JBrowse link
G Chst2 carbohydrate sulfotransferase 2 increases expression ISO hydroquinone results in increased expression of CHST2 mRNA CTD PMID:31256213 NCBI chr 8:95,960,067...95,966,312
Ensembl chr 8:95,959,826...95,966,955 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO hydroquinone inhibits the reaction [TNF protein results in increased phosphorylation of CHUK protein] CTD PMID:23288922 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065 		JBrowse link
G Clca4 chloride channel accessory 4 decreases expression ISO hydroquinone results in decreased expression of CLCA4 mRNA CTD PMID:31256213 NCBI chr 2:233,883,625...233,904,993
Ensembl chr 2:233,883,851...233,903,089 		JBrowse link
G Cldn8 claudin 8 decreases expression ISO hydroquinone results in decreased expression of CLDN8 mRNA CTD PMID:31256213 NCBI chr11:27,875,857...27,878,106
Ensembl chr11:27,875,692...27,878,513 		JBrowse link
G Clic3 chloride intracellular channel 3 increases expression ISO hydroquinone results in increased expression of CLIC3 mRNA CTD PMID:31256213 NCBI chr 3:8,271,416...8,274,023
Ensembl chr 3:8,272,097...8,274,018 		JBrowse link
G Clmp CXADR-like membrane protein increases expression ISO hydroquinone results in increased expression of CLMP mRNA CTD PMID:31256213 NCBI chr 8:41,060,527...41,168,841
Ensembl chr 8:41,060,799...41,168,838 		JBrowse link
G Cmpk2 cytidine/uridine monophosphate kinase 2 decreases expression ISO hydroquinone results in decreased expression of CMPK2 mRNA CTD PMID:31256213 NCBI chr 6:43,073,706...43,085,183
Ensembl chr 6:43,073,796...43,085,183 		JBrowse link
G Cnfn cornifelin increases expression ISO hydroquinone results in increased expression of CNFN mRNA CTD PMID:31256213 NCBI chr 1:80,949,699...80,953,747
Ensembl chr 1:80,951,600...80,953,747 		JBrowse link
G Cnmd chondromodulin increases response to substance
increases expression
multiple interactions		 ISO CNMD protein results in increased susceptibility to hydroquinone
hydroquinone results in increased expression of CNMD mRNA
Dactinomycin inhibits the reaction [hydroquinone results in increased expression of CNMD protein]; hydroquinone results in increased expression of and results in increased secretion of CNMD protein; NQO1 protein inhibits the reaction [CNMD protein results in increased susceptibility to hydroquinone]; NQO1 protein inhibits the reaction [hydroquinone results in increased expression of CNMD protein]		 CTD PMID:19525446 NCBI chr15:55,041,548...55,066,297
Ensembl chr15:55,041,561...55,066,297 		JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression
multiple interactions		 ISO hydroquinone results in increased expression of COL1A1 protein
[TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]		 CTD PMID:18055817 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions EXP [COL2A1 protein co-treated with Freund's Adjuvant co-treated with hydroquinone] results in increased expression of and results in increased secretion of TNF protein; [COL2A1 protein co-treated with Freund's Adjuvant co-treated with hydroquinone] results in increased secretion of IL1B protein; [COL2A1 protein co-treated with hydroquinone] results in increased expression of IL6 protein CTD PMID:29908986 PMID:29935983 NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546 		JBrowse link
G Col4a1 collagen type IV alpha 1 chain decreases expression
increases expression
multiple interactions		 ISO hydroquinone results in decreased expression of COL4A1 mRNA
hydroquinone results in increased expression of COL4A1 protein
[TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]		 CTD PMID:18055817 NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412 		JBrowse link
G Col5a2 collagen type V alpha 2 chain decreases expression ISO hydroquinone results in decreased expression of COL5A2 mRNA CTD PMID:31256213 NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154 		JBrowse link
G Crct1 cysteine-rich C-terminal 1 increases expression ISO hydroquinone results in increased expression of CRCT1 mRNA CTD PMID:31256213 NCBI chr 2:178,633,789...178,635,274
Ensembl chr 2:178,634,092...178,634,394 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions
increases phosphorylation		 ISO 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in increased phosphorylation of CREB1 protein]; CREB1 protein affects the reaction [hydroquinone results in increased expression of PPP2CA protein]; CREB1 protein affects the reaction [hydroquinone results in increased expression of TNF protein]; hydroquinone promotes the reaction [CREB1 protein binds to PPP2CA promoter] CTD PMID:23288922 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Crispld2 cysteine-rich secretory protein LCCL domain containing 2 increases expression ISO hydroquinone results in increased expression of CRISPLD2 mRNA CTD PMID:31256213 NCBI chr19:48,053,153...48,111,485
Ensembl chr19:48,053,287...48,110,465 		JBrowse link
G Crybg2 crystallin beta-gamma domain containing 2 increases expression ISO hydroquinone results in increased expression of CRYBG2 mRNA CTD PMID:29221148 NCBI chr 5:146,286,406...146,318,417
Ensembl chr 5:146,286,925...146,323,666 		JBrowse link
G Csf1r colony stimulating factor 1 receptor multiple interactions ISO hydroquinone promotes the reaction [[CSF1R protein co-treated with Lipopolysaccharides] results in increased abundance of Nitric Oxide] CTD PMID:7884313 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions
decreases secretion		 ISO [CSF2 protein co-treated with hydroquinone] results in increased phosphorylation of and results in increased activity of MAPK1 protein; [CSF2 protein co-treated with hydroquinone] results in increased phosphorylation of and results in increased activity of MAPK3 protein
hydroquinone results in decreased secretion of CSF2 protein
hydroquinone promotes the reaction [[CSF2 protein co-treated with Lipopolysaccharides] results in increased abundance of Nitric Oxide]		 CTD PMID:7884313 PMID:15129224 PMID:23559866 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 increases expression ISO hydroquinone results in increased expression of CSGALNACT1 mRNA CTD PMID:31256213 NCBI chr16:20,995,210...21,330,586
Ensembl chr16:21,235,784...21,330,319 		JBrowse link
G Csrnp3 cysteine and serine rich nuclear protein 3 decreases expression ISO hydroquinone results in decreased expression of CSRNP3 mRNA CTD PMID:31256213 NCBI chr 3:50,498,379...50,695,598
Ensembl chr 3:50,498,633...50,685,950 		JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 decreases expression ISO hydroquinone results in decreased expression of CSRP2 mRNA CTD PMID:31256213 NCBI chr 7:46,349,109...46,367,743
Ensembl chr 7:46,348,686...46,367,745 		JBrowse link
G Cst6 cystatin E/M increases expression ISO hydroquinone results in increased expression of CST6 mRNA CTD PMID:31256213 NCBI chr 1:202,655,322...202,657,030
Ensembl chr 1:202,655,322...202,657,030 		JBrowse link
G Cth cystathionine gamma-lyase increases expression ISO hydroquinone results in increased expression of CTH mRNA CTD PMID:31256213 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
affects localization
decreases expression		 ISO hydroquinone inhibits the reaction [CTNNB1 protein binds to LEF1 protein]; hydroquinone results in increased expression of and results in decreased phosphorylation of CTNNB1 protein; IGF1 protein inhibits the reaction [hydroquinone results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [hydroquinone results in decreased expression of CTNNB1 protein]; PPP2CA protein affects the reaction [hydroquinone affects the localization of CTNNB1 protein]; PPP2CA protein affects the reaction [hydroquinone results in increased expression of and results in decreased phosphorylation of CTNNB1 protein]; PPP2R5A protein affects the reaction [hydroquinone affects the localization of CTNNB1 protein]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of and results in decreased phosphorylation of CTNNB1 protein] CTD PMID:28886972 PMID:30567741 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression
decreases secretion		 ISO hydroquinone results in decreased expression of CXCL12 mRNA
hydroquinone results in decreased secretion of CXCL12 protein		 CTD PMID:22960397 PMID:23559866 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cycs cytochrome c, somatic affects localization
increases expression
multiple interactions		 ISO hydroquinone affects the localization of CYCS protein
hydroquinone results in increased expression of CYCS protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of CYCS protein]; 2-tert-butylhydroquinone inhibits the reaction [hydroquinone results in increased expression of CYCS protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of CYCS protein]		 CTD PMID:15777082 PMID:15816534 PMID:35123993 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 affects response to substance
multiple interactions
increases expression		 ISO CYP1A1 protein affects the susceptibility to hydroquinone
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of CYP1A1 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of CYP1A1 protein]
hydroquinone results in increased expression of CYP1A1 mRNA; hydroquinone results in increased expression of CYP1A1 protein		 CTD PMID:8242868 PMID:23416264 PMID:31256213 PMID:35123993 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO hydroquinone results in increased expression of CYP1B1 mRNA CTD PMID:23416264 PMID:31256213 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions EXP [CYP2B1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone CTD PMID:8211999 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 affects response to substance ISO CYP2B1 protein affects the susceptibility to hydroquinone CTD PMID:8242868 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions ISO [CYP2D6 protein results in increased metabolism of bisphenol A] which results in increased chemical synthesis of hydroquinone CTD PMID:21402134 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
increases expression		 EXP
ISO		 [CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone; [CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of hydroquinone; [Glutathione co-treated with [CYP2E1 protein results in increased metabolism of Phenol]] results in increased chemical synthesis of [Glutathione binds to hydroquinone metabolite]; EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone]; EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of hydroquinone]
hydroquinone results in increased expression of CYP2E1 mRNA
Resveratrol inhibits the reaction [hydroquinone results in increased expression of CYP2E1 mRNA]
hydroquinone results in increased expression of CYP2E1 mRNA; hydroquinone results in increased expression of CYP2E1 protein
[CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of hydroquinone; PPP2CA protein affects the reaction [hydroquinone results in increased expression of CYP2E1 protein]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of CYP2E1 mRNA]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of CYP2E1 protein]		 CTD PMID:8211999 PMID:15051535 PMID:23202692 PMID:30567741 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO [CYP3A4 protein results in increased metabolism of bisphenol A] which results in increased chemical synthesis of hydroquinone CTD PMID:21402134 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions ISO [CYP3A5 protein results in increased metabolism of bisphenol A] which results in increased chemical synthesis of hydroquinone CTD PMID:21402134 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422 		JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 increases expression ISO hydroquinone results in increased expression of CYP4F18 mRNA; hydroquinone results in increased expression of CYP4F18 protein CTD PMID:23940708 NCBI chr16:17,763,543...17,804,944
Ensembl chr16:17,707,317...17,804,940 		JBrowse link
G Cysrt1 cysteine rich tail 1 increases expression ISO hydroquinone results in increased expression of CYSRT1 mRNA CTD PMID:31256213 NCBI chr 3:8,054,195...8,057,846
Ensembl chr 3:8,053,482...8,059,721 		JBrowse link
G Dap death-associated protein decreases expression ISO hydroquinone results in decreased expression of DAP mRNA CTD PMID:15452088 NCBI chr 2:82,199,206...82,251,771
Ensembl chr 2:82,199,280...82,251,752 		JBrowse link
G Dapl1 death associated protein-like 1 decreases expression ISO hydroquinone results in decreased expression of DAPL1 mRNA CTD PMID:31256213 NCBI chr 3:43,960,993...43,980,940
Ensembl chr 3:43,960,810...43,980,940 		JBrowse link
G Dapp1 dual adaptor of phosphotyrosine and 3-phosphoinositides 1 increases expression ISO hydroquinone results in increased expression of DAPP1 mRNA CTD PMID:31256213 NCBI chr 2:226,425,890...226,475,445
Ensembl chr 2:226,425,898...226,475,423 		JBrowse link
G Dbt dihydrolipoamide branched chain transacylase E2 decreases expression ISO hydroquinone results in decreased expression of DBT mRNA CTD PMID:31256213 NCBI chr 2:204,481,744...204,510,612
Ensembl chr 2:204,481,737...204,510,609 		JBrowse link
G Dcun1d3 defective in cullin neddylation 1 domain containing 3 increases expression ISO hydroquinone results in increased expression of DCUN1D3 mRNA CTD PMID:31256213 NCBI chr 1:174,243,001...174,285,647
Ensembl chr 1:66,494,848...66,496,343
Ensembl chr 1:66,494,848...66,496,343 		JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 decreases expression ISO hydroquinone results in decreased expression of DDAH1 mRNA CTD PMID:31256213 NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions		 ISO hydroquinone results in increased expression of DDIT3 mRNA; hydroquinone results in increased expression of DDIT3 protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of and affects the localization of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of DDIT3 protein]; hydroquinone results in increased expression of and affects the localization of DDIT3 protein; ursodoxicoltaurine inhibits the reaction [hydroquinone results in increased expression of and affects the localization of DDIT3 protein]; XBP1 protein alternative form inhibits the reaction [hydroquinone results in increased expression of DDIT3 protein]
[XBP1 protein affects the susceptibility to hydroquinone] which affects the expression of DDIT3 protein; hydroquinone promotes the reaction [XBP1 protein affects the expression of DDIT3 mRNA]; XBP1 protein affects the reaction [hydroquinone results in increased expression of DDIT3 mRNA]; XBP1 protein affects the reaction [hydroquinone results in increased expression of DDIT3 protein]		 CTD PMID:23416264 PMID:24053669 PMID:31256213 PMID:32334435 PMID:36646296 More... NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO hydroquinone results in increased expression of DDIT4 mRNA CTD PMID:23416264 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105 		JBrowse link
G Ddx60 DEXD/H-box helicase 60 decreases expression ISO hydroquinone results in decreased expression of DDX60 mRNA CTD PMID:31256213 NCBI chr16:28,077,000...28,197,903
Ensembl chr16:28,076,999...28,179,526 		JBrowse link
G Depdc7 DEP domain containing 7 decreases expression ISO hydroquinone results in decreased expression of DEPDC7 mRNA CTD PMID:31256213 NCBI chr 3:91,099,111...91,121,152
Ensembl chr 3:91,099,835...91,121,124 		JBrowse link
G Deptor DEP domain containing MTOR-interacting protein decreases expression ISO hydroquinone results in decreased expression of DEPTOR mRNA CTD PMID:29221148 NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773 		JBrowse link
G Dffb DNA fragmentation factor subunit beta decreases expression ISO hydroquinone results in decreased expression of DFFB mRNA CTD PMID:31256213 NCBI chr 5:164,522,446...164,534,733
Ensembl chr 5:164,522,463...164,534,628 		JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 affects expression ISO hydroquinone affects the expression of DKK1 mRNA CTD PMID:22960397 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202 		JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 increases expression ISO hydroquinone results in increased expression of DNAJA1 mRNA CTD PMID:15452088 NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967 		JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 increases expression ISO hydroquinone results in increased expression of DNAJB1 mRNA CTD PMID:15452088 NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458 		JBrowse link
G Dner delta/notch-like EGF repeat containing decreases expression ISO hydroquinone results in decreased expression of DNER mRNA CTD PMID:31256213 NCBI chr 9:85,586,985...85,902,461
Ensembl chr 9:85,586,987...85,902,637 		JBrowse link
G Dnmt1 DNA methyltransferase 1 decreases expression
increases expression
affects expression		 ISO hydroquinone results in decreased expression of DNMT1 mRNA; hydroquinone results in decreased expression of DNMT1 protein
hydroquinone results in increased expression of DNMT1 mRNA
hydroquinone affects the expression of DNMT1 mRNA		 CTD PMID:22245671 PMID:27979589 PMID:31899212 PMID:34612549 PMID:35135009 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha decreases expression
affects expression
increases expression		 ISO hydroquinone results in decreased expression of DNMT3A mRNA; hydroquinone results in decreased expression of DNMT3A protein
hydroquinone affects the expression of DNMT3A mRNA
hydroquinone results in increased expression of DNMT3A mRNA		 CTD PMID:22245671 PMID:27979589 PMID:31899212 PMID:34612549 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta decreases expression
multiple interactions
affects expression		 ISO hydroquinone results in decreased expression of DNMT3B mRNA
Decitabine affects the reaction [hydroquinone affects the expression of DNMT3B mRNA]; trichostatin A affects the reaction [hydroquinone affects the expression of DNMT3B mRNA]		 CTD PMID:22245671 PMID:31899212 PMID:34612549 NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124 		JBrowse link
G Dtx3l deltex E3 ubiquitin ligase 3L decreases expression ISO hydroquinone results in decreased expression of DTX3L mRNA CTD PMID:31256213 NCBI chr11:64,814,926...64,824,539
Ensembl chr11:64,814,926...64,824,538 		JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO hydroquinone results in increased expression of DUSP1 protein CTD PMID:23290930 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Dusp19 dual specificity phosphatase 19 decreases expression ISO hydroquinone results in decreased expression of DUSP19 mRNA CTD PMID:31256213 NCBI chr 3:65,538,424...65,554,465
Ensembl chr 3:65,538,420...65,553,534 		JBrowse link
G Dusp5 dual specificity phosphatase 5 increases expression ISO hydroquinone results in increased expression of DUSP5 mRNA CTD PMID:31256213 NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818 		JBrowse link
G Dusp6 dual specificity phosphatase 6 increases expression ISO hydroquinone results in increased expression of DUSP6 mRNA CTD PMID:31256213 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185 		JBrowse link
G Dzip1 DAZ interacting zinc finger protein 1 decreases expression ISO hydroquinone results in decreased expression of DZIP1 mRNA CTD PMID:31256213 NCBI chr15:95,956,329...96,009,994
Ensembl chr15:95,956,398...96,010,066 		JBrowse link
G E2f1 E2F transcription factor 1 increases expression
multiple interactions		 ISO hydroquinone results in increased expression of E2F1 mRNA; hydroquinone results in increased expression of E2F1 protein
MIR7-2 promotes the reaction [hydroquinone results in increased expression of E2F1 protein]		 CTD PMID:33932074 PMID:37951342 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361 		JBrowse link
G E4f1 E4F transcription factor 1 increases expression
affects response to substance
multiple interactions		 ISO hydroquinone results in increased expression of E4F1 mRNA; hydroquinone results in increased expression of E4F1 protein
E4F1 protein affects the susceptibility to hydroquinone
[E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of H2AX protein modified form; [E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of RB1 protein; [E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of RB1 protein modified form		 CTD PMID:30448557 PMID:30506647 NCBI chr10:13,471,478...13,495,018
Ensembl chr10:13,474,456...13,485,974 		JBrowse link
G Ecm2 extracellular matrix protein 2 increases expression ISO hydroquinone results in increased expression of ECM2 mRNA CTD PMID:31256213 NCBI chr17:15,120,194...15,152,536
Ensembl chr17:15,120,196...15,152,516 		JBrowse link
G Edn1 endothelin 1 decreases expression ISO hydroquinone results in decreased expression of EDN1 mRNA CTD PMID:31256213 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Edn2 endothelin 2 decreases expression ISO hydroquinone results in decreased expression of EDN2 mRNA CTD PMID:31256213 NCBI chr 5:133,751,316...133,756,814
Ensembl chr 5:133,751,217...133,756,814 		JBrowse link
G Eef2k eukaryotic elongation factor-2 kinase decreases expression ISO hydroquinone results in decreased expression of EEF2K mRNA CTD PMID:31256213 NCBI chr 1:175,393,119...175,456,756
Ensembl chr 1:175,393,154...175,455,164 		JBrowse link
G Efna1 ephrin A1 multiple interactions ISO [hydroquinone co-treated with Hemin] affects the expression of EFNA1 mRNA CTD PMID:32198055 NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866 		JBrowse link
G Egr3 early growth response 3 increases expression ISO hydroquinone results in increased expression of EGR3 mRNA CTD PMID:31256213 NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627 		JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 decreases expression ISO hydroquinone results in decreased expression of EHMT2 protein CTD PMID:27979589 NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547 		JBrowse link
G Eid3 EP300 interacting inhibitor of differentiation 3 decreases expression ISO hydroquinone results in decreased expression of EID3 mRNA CTD PMID:31256213 NCBI chr 7:20,860,073...20,861,395 JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases phosphorylation
increases expression
multiple interactions		 ISO hydroquinone results in increased phosphorylation of EIF2AK3 protein
hydroquinone results in increased expression of EIF2AK3 protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of EIF2AK3 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of EIF2AK3 protein]		 CTD PMID:24053669 PMID:36646296 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha multiple interactions
increases phosphorylation		 ISO XBP1 protein alternative form inhibits the reaction [hydroquinone results in increased phosphorylation of EIF2S1 protein] CTD PMID:24053669 PMID:37148176 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 increases expression ISO hydroquinone results in increased expression of EIF4EBP1 mRNA CTD PMID:31256213 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984 		JBrowse link
G Elavl1 ELAV like RNA binding protein 1 multiple interactions
increases degradation
decreases expression		 ISO ELAVL1 protein inhibits the reaction [hydroquinone results in decreased expression of SIRT3 mRNA]; ELAVL1 protein inhibits the reaction [hydroquinone results in decreased expression of SIRT3 protein]; ELAVL1 protein inhibits the reaction [hydroquinone results in increased degradation of SIRT3 mRNA]; NOX4 protein promotes the reaction [hydroquinone results in decreased expression of ELAVL1 mRNA]; NOX4 protein promotes the reaction [hydroquinone results in decreased expression of ELAVL1 protein]; SIDT2 protein promotes the reaction [hydroquinone results in decreased expression of ELAVL1 mRNA]
hydroquinone results in increased degradation of ELAVL1 mRNA
hydroquinone results in decreased expression of ELAVL1 mRNA; hydroquinone results in decreased expression of ELAVL1 protein		 CTD PMID:35302183 NCBI chr12:2,640,936...2,684,787
Ensembl chr12:2,645,061...2,684,784 		JBrowse link
G Elavl2 ELAV like RNA binding protein 2 multiple interactions ISO [[NOX4 protein results in decreased expression of ELAVL2 protein] which promotes the reaction SIDT2 protein] promotes the reaction [hydroquinone results in decreased degradation of SIRT3 protein] CTD PMID:35302183 NCBI chr 5:105,960,872...106,086,463
Ensembl chr 5:105,960,875...106,109,097 		JBrowse link
G Elf3 E74 like ETS transcription factor 3 increases expression ISO hydroquinone results in increased expression of ELF3 mRNA CTD PMID:23416264 NCBI chr13:46,690,460...46,695,394
Ensembl chr13:46,690,466...46,695,481 		JBrowse link
G Elf5 E74 like ETS transcription factor 5 increases expression ISO hydroquinone results in increased expression of ELF5 mRNA CTD PMID:31256213 NCBI chr 3:89,808,837...89,836,977
Ensembl chr 3:89,797,880...89,836,973 		JBrowse link
G Elmod1 ELMO domain containing 1 increases expression ISO hydroquinone results in increased expression of ELMOD1 mRNA CTD PMID:31256213 NCBI chr 8:54,298,363...54,355,348
Ensembl chr 8:54,298,363...54,355,140 		JBrowse link
G Elovl4 ELOVL fatty acid elongase 4 increases expression ISO hydroquinone results in increased expression of ELOVL4 mRNA CTD PMID:31256213 NCBI chr 8:84,702,916...84,729,466
Ensembl chr 8:84,702,362...84,729,697 		JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 decreases expression ISO hydroquinone results in decreased expression of ELOVL5 mRNA CTD PMID:31256213 NCBI chr 8:78,790,846...78,857,307
Ensembl chr 8:78,790,846...78,857,284 		JBrowse link
G Elp2 elongator acetyltransferase complex subunit 2 decreases expression ISO hydroquinone results in decreased expression of ELP2 mRNA CTD PMID:31256213 NCBI chr18:15,885,940...15,921,564
Ensembl chr18:15,885,934...15,921,599 		JBrowse link
G Epb41l3 erythrocyte membrane protein band 4.1-like 3 increases expression ISO hydroquinone results in increased expression of EPB41L3 mRNA CTD PMID:31256213 NCBI chr 9:109,056,178...109,260,607
Ensembl chr 9:109,016,113...109,260,607 		JBrowse link
G Ephx1 epoxide hydrolase 1 multiple interactions EXP EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone]; EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of hydroquinone] CTD PMID:8211999 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Eps8l1 EPS8-like 1 increases expression ISO hydroquinone results in increased expression of EPS8L1 mRNA CTD PMID:31256213 NCBI chr 1:69,343,202...69,359,778
Ensembl chr 1:69,344,243...69,363,524 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 decreases expression ISO hydroquinone results in decreased expression of ERBB2 mRNA CTD PMID:22245671 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Ereg epiregulin increases expression ISO hydroquinone results in increased expression of EREG mRNA CTD PMID:31256213 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G Erich5 glutamate-rich 5 decreases expression ISO hydroquinone results in decreased expression of ERICH5 mRNA CTD PMID:31256213 NCBI chr 7:65,655,829...65,682,221
Ensembl chr 7:65,657,204...65,680,207 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions
increases expression		 ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of ERN1 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of ERN1 protein] CTD PMID:36646296 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G Esr1 estrogen receptor 1 decreases expression ISO hydroquinone results in decreased expression of ESR1 mRNA CTD PMID:31256213 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Etv4 ETS variant transcription factor 4 increases expression ISO hydroquinone results in increased expression of ETV4 mRNA CTD PMID:31256213 NCBI chr10:86,706,749...86,721,974
Ensembl chr10:86,706,749...86,721,974 		JBrowse link
G Exosc3 exosome component 3 decreases expression ISO hydroquinone results in decreased expression of EXOSC3 mRNA CTD PMID:31256213 NCBI chr 5:59,573,849...59,579,065
Ensembl chr 5:59,573,886...59,579,060 		JBrowse link
G Exosc6 exosome component 6 increases expression ISO hydroquinone results in increased expression of EXOSC6 mRNA CTD PMID:31256213 NCBI chr19:39,022,171...39,023,585
Ensembl chr19:39,022,183...39,023,515 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit decreases expression ISO hydroquinone results in decreased expression of EZH2 protein CTD PMID:27979589 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G F2r coagulation factor II (thrombin) receptor decreases expression ISO hydroquinone results in decreased expression of F2R mRNA CTD PMID:31256213 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870 		JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions ISO [KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of FABP4 mRNA CTD PMID:37245849 NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578 		JBrowse link
G Fadd Fas associated via death domain decreases expression
multiple interactions		 ISO hydroquinone results in decreased expression of FADD mRNA
FADD protein affects the reaction [hydroquinone results in increased cleavage of BID protein]; FADD protein affects the reaction [hydroquinone results in increased cleavage of CASP3 protein]; FADD protein affects the reaction [hydroquinone results in increased cleavage of CASP8 protein]		 CTD PMID:15452088 PMID:23288922 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Fahd2a fumarylacetoacetate hydrolase domain containing 2A decreases expression ISO hydroquinone results in decreased expression of FAHD2A mRNA CTD PMID:31256213 NCBI chr 3:114,657,176...114,665,349
Ensembl chr 3:114,655,865...114,665,356 		JBrowse link
G Fam117b family with sequence similarity 117, member B decreases expression ISO hydroquinone results in decreased expression of FAM117B mRNA CTD PMID:31256213 NCBI chr 9:61,340,284...61,418,531
Ensembl chr 9:61,340,249...61,408,483 		JBrowse link
G Fam13a family with sequence similarity 13, member A decreases expression ISO hydroquinone results in decreased expression of FAM13A mRNA CTD PMID:31256213 NCBI chr 4:88,056,521...88,155,782
Ensembl chr 4:88,058,403...88,155,860 		JBrowse link
G Fam43a family with sequence similarity 43, member A increases expression ISO hydroquinone results in increased expression of FAM43A mRNA CTD PMID:31256213 NCBI chr11:70,128,253...70,131,401
Ensembl chr11:70,128,253...70,131,401 		JBrowse link
G Fam83d family with sequence similarity 83, member D decreases expression ISO hydroquinone results in decreased expression of FAM83D mRNA CTD PMID:23416264 NCBI chr 3:147,421,941...147,441,211
Ensembl chr 3:147,421,908...147,441,192 		JBrowse link
G Fas Fas cell surface death receptor increases expression
multiple interactions		 ISO hydroquinone results in increased expression of FAS protein
[PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of FAS protein		 CTD PMID:23776099 PMID:28444915 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand increases expression ISO hydroquinone results in increased expression of FASLG protein CTD PMID:23776099 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fau FAU ubiquitin like and ribosomal protein S30 fusion multiple interactions ISO FAU protein affects the reaction [hydroquinone results in increased expression of and results in increased activity of NQO1 protein]; FAU protein affects the reaction [hydroquinone results in increased expression of H2AX protein] CTD PMID:22687461 NCBI chr 1:203,350,226...203,351,741
Ensembl chr 1:203,350,189...203,351,742
Ensembl chr 1:203,350,189...203,351,742
Ensembl chr 6:203,350,189...203,351,742 		JBrowse link
G Fbxo5 F-box protein 5 decreases expression ISO hydroquinone results in decreased expression of FBXO5 mRNA CTD PMID:23416264 NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 decreases expression ISO hydroquinone results in decreased expression of FGFR3 mRNA CTD PMID:31256213 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
G Fibin fin bud initiation factor homolog increases expression ISO hydroquinone results in increased expression of FIBIN mRNA CTD PMID:31256213 NCBI chr 3:96,942,405...96,944,676
Ensembl chr 3:96,942,406...96,944,676 		JBrowse link
G Flg filaggrin increases expression ISO hydroquinone results in increased expression of FLG mRNA; hydroquinone results in increased expression of FLG protein CTD PMID:25240866 NCBI chr 2:178,884,793...178,912,986 JBrowse link
G Flg2 filaggrin 2 increases expression ISO hydroquinone results in increased expression of FLG2 mRNA CTD PMID:25240866 NCBI chr 2:178,789,792...178,802,232 JBrowse link
G Fn1 fibronectin 1 affects expression ISO hydroquinone affects the expression of FN1 mRNA CTD PMID:15452088 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression
increases phosphorylation
multiple interactions		 ISO hydroquinone results in decreased expression of FOS mRNA
hydroquinone results in increased phosphorylation of FOS protein
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in increased phosphorylation of FOS protein]; FOS protein affects the reaction [hydroquinone results in decreased expression of MIR122 mRNA]; FOS protein affects the reaction [hydroquinone results in increased expression of ADAM17 mRNA]; FOS protein affects the reaction [hydroquinone results in increased expression of ADAM17 protein]; hydroquinone promotes the reaction [FOS protein binds to MIR122 promoter]		 CTD PMID:15452088 PMID:23791922 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO hydroquinone results in increased expression of FOSL1 mRNA CTD PMID:31256213 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930 		JBrowse link
G Fry FRY microtubule binding protein increases expression ISO hydroquinone results in increased expression of FRY mRNA CTD PMID:31256213 NCBI chr12:4,493,890...4,887,118
Ensembl chr12:4,493,891...4,799,116 		JBrowse link
G Fsip1 fibrous sheath interacting protein 1 increases expression ISO hydroquinone results in increased expression of FSIP1 mRNA CTD PMID:31256213 NCBI chr 3:105,074,584...105,217,180
Ensembl chr 3:105,068,543...105,217,167 		JBrowse link
G Fth1 ferritin heavy chain 1 increases expression ISO hydroquinone results in increased expression of FTH1 mRNA; hydroquinone results in increased expression of FTH1 protein CTD PMID:15452088 PMID:23738040 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424 		JBrowse link
G Fut1 fucosyltransferase 1 decreases expression ISO hydroquinone results in decreased expression of FUT1 mRNA CTD PMID:29221148 NCBI chr 1:96,086,934...96,090,352
Ensembl chr 1:96,086,635...96,090,616 		JBrowse link
G Fzd2 frizzled class receptor 2 decreases expression ISO hydroquinone results in decreased expression of FZD2 mRNA CTD PMID:31256213 NCBI chr10:87,561,866...87,563,776
Ensembl chr10:87,561,326...87,565,334 		JBrowse link
G G0s2 G0/G1switch 2 increases expression ISO hydroquinone results in increased expression of G0S2 mRNA CTD PMID:31256213 NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO hydroquinone results in increased expression of GADD45A mRNA CTD PMID:23416264 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gas1 growth arrest-specific 1 decreases expression ISO hydroquinone results in decreased expression of GAS1 mRNA CTD PMID:31256213 NCBI chr17:4,482,168...4,485,153 JBrowse link
G Gask1b golgi associated kinase 1B decreases expression ISO hydroquinone results in decreased expression of GASK1B mRNA CTD PMID:31256213 NCBI chr 2:165,047,689...165,112,479
Ensembl chr 2:165,047,684...165,112,477 		JBrowse link
G Gata1 GATA binding protein 1 decreases expression
multiple interactions		 ISO hydroquinone results in decreased expression of GATA1 mRNA
Decitabine inhibits the reaction [hydroquinone inhibits the reaction [Hemin results in increased expression of GATA1 mRNA]]; hydroquinone inhibits the reaction [GATA1 protein binds to HBA1 gene]; hydroquinone inhibits the reaction [GATA1 protein binds to HBD gene]; hydroquinone inhibits the reaction [GATA1 protein binds to HBG1 gene]; hydroquinone inhibits the reaction [Hemin results in increased expression of GATA1 mRNA]		 CTD PMID:21414390 PMID:23973255 PMID:37329354 NCBI chr  X:14,529,706...14,537,530
Ensembl chr  X:14,529,702...14,537,530 		JBrowse link
G Gata2 GATA binding protein 2 multiple interactions
decreases expression		 ISO hydroquinone affects the reaction [Hemin affects the expression of GATA2 mRNA]; hydroquinone inhibits the reaction [Hemin results in decreased expression of GATA2 protein]; hydroquinone promotes the reaction [GATA2 protein binds to HBB gene]; hydroquinone promotes the reaction [GATA2 protein binds to HBG2 gene]; hydroquinone promotes the reaction [GATA2 protein binds to HBM gene]; hydroquinone promotes the reaction [GATA2 protein binds to HBP1 gene]; hydroquinone promotes the reaction [Hemin results in decreased expression of GATA2 mRNA]
hydroquinone results in decreased expression of GATA2 mRNA		 CTD PMID:21414390 PMID:37329354 NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761 		JBrowse link
G Gbp2 guanylate binding protein 2 decreases expression ISO hydroquinone results in decreased expression of GBP2 mRNA CTD PMID:31256213 NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
multiple interactions
affects methylation		 ISO hydroquinone results in increased expression of GCLC mRNA; hydroquinone results in increased expression of GCLC protein
[hydroquinone affects the methylation of GCLC promoter] which results in decreased abundance of 5-Methylcytosine; [hydroquinone affects the methylation of GCLC promoter] which results in increased abundance of 5-hydroxymethylcytosine; Resveratrol promotes the reaction [hydroquinone results in increased expression of GCLC mRNA]; TET1 protein affects the reaction [hydroquinone results in increased expression of GCLC mRNA]		 CTD PMID:23290930 PMID:23940045 PMID:30547568 PMID:32334435 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO hydroquinone results in increased expression of GCLM mRNA; hydroquinone results in increased expression of GCLM protein CTD PMID:21059386 PMID:30547568 PMID:31256213 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gda guanine deaminase increases expression ISO hydroquinone results in increased expression of GDA mRNA CTD PMID:31256213 NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416 		JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO hydroquinone results in increased expression of GDF15 mRNA CTD PMID:23416264 PMID:31256213 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055 		JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 increases expression ISO hydroquinone results in increased expression of GDPD3 mRNA CTD PMID:31256213 NCBI chr 1:181,373,505...181,383,063
Ensembl chr 1:181,366,626...181,383,063 		JBrowse link
G Gfpt1 glutamine fructose-6-phosphate transaminase 1 increases expression ISO hydroquinone results in increased expression of GFPT1 mRNA CTD PMID:31256213 NCBI chr 4:119,496,691...119,546,472
Ensembl chr 4:119,496,714...119,546,471 		JBrowse link
G Gk glycerol kinase increases expression ISO hydroquinone results in increased expression of GK mRNA CTD PMID:31256213 NCBI chr  X:50,162,089...50,238,707
Ensembl chr  X:50,163,123...50,238,631 		JBrowse link
G Glmp glycosylated lysosomal membrane protein decreases expression ISO hydroquinone results in decreased expression of GLMP mRNA CTD PMID:31256213 NCBI chr 2:173,794,273...173,797,863
Ensembl chr 2:173,794,255...173,799,960 		JBrowse link
G Glrx glutaredoxin increases expression ISO hydroquinone results in increased expression of GLRX mRNA CTD PMID:31256213 NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680 		JBrowse link
G Glul glutamate-ammonia ligase decreases expression ISO hydroquinone results in decreased expression of GLUL mRNA CTD PMID:31256213 NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108 		JBrowse link
G Gmpr guanosine monophosphate reductase decreases expression ISO hydroquinone results in decreased expression of GMPR mRNA CTD PMID:31256213 NCBI chr17:19,151,820...19,189,626
Ensembl chr17:19,151,815...19,189,621 		JBrowse link
G Gosr2 golgi SNAP receptor complex member 2 decreases expression ISO hydroquinone results in decreased expression of GOSR2 mRNA CTD PMID:31256213 NCBI chr10:88,585,291...88,605,642
Ensembl chr10:88,586,299...88,605,625 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 increases expression ISO hydroquinone results in increased expression of GOT1 mRNA CTD PMID:31256213 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 increases expression ISO hydroquinone results in increased expression of GPAT3 mRNA CTD PMID:31256213 NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490 		JBrowse link
G Gpr155 G protein-coupled receptor 155 decreases expression ISO hydroquinone results in decreased expression of GPR155 mRNA CTD PMID:31256213 NCBI chr 3:58,216,422...58,270,350
Ensembl chr 3:58,216,423...58,270,275 		JBrowse link
G Gpr15lg G protein-coupled receptor 15 ligand decreases expression ISO hydroquinone results in decreased expression of GPR15LG mRNA CTD PMID:31256213 NCBI chr16:12,868,270...12,875,876
Ensembl chr16:12,868,270...12,875,876 		JBrowse link
G Gprc5a G protein-coupled receptor, class C, group 5, member A decreases expression ISO hydroquinone results in decreased expression of GPRC5A mRNA CTD PMID:31256213 NCBI chr 4:167,903,542...167,922,276
Ensembl chr 4:167,903,542...167,922,260 		JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression ISO hydroquinone results in increased expression of GPX2 mRNA CTD PMID:31256213 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877 		JBrowse link
G Grb10 growth factor receptor bound protein 10 increases expression ISO hydroquinone results in increased expression of GRB10 mRNA CTD PMID:31256213 NCBI chr14:86,495,051...86,602,800
Ensembl chr14:86,495,054...86,602,806 		JBrowse link
G Grb2 growth factor receptor bound protein 2 affects expression ISO hydroquinone affects the expression of GRB2 protein CTD PMID:20021034 NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309 		JBrowse link
G Grhl1 grainyhead-like transcription factor 1 increases expression ISO hydroquinone results in increased expression of GRHL1 mRNA CTD PMID:31256213 NCBI chr 6:41,207,325...41,257,516
Ensembl chr 6:41,207,348...41,254,301 		JBrowse link
G Gsdmd gasdermin D increases expression
multiple interactions		 ISO hydroquinone results in increased expression of GSDMD protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of GSDMD protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of GSDMD protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of GSDMD protein]		 CTD PMID:36646296 NCBI chr 7:107,542,489...107,547,051
Ensembl chr 7:107,542,083...107,547,055 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO hydroquinone results in increased expression of and results in decreased phosphorylation of and results in increased activity of GSK3B protein; IGF1 protein inhibits the reaction [hydroquinone results in decreased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of GSK3B protein] CTD PMID:28886972 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO hydroquinone inhibits the reaction [Peroxynitrous Acid results in decreased activity of GSR protein] CTD PMID:15831208 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Gss glutathione synthetase increases expression
multiple interactions		 ISO hydroquinone results in increased expression of GSS protein
NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of GSS protein]		 CTD PMID:21059386 NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 affects response to substance ISO GSTM1 affects the susceptibility to hydroquinone; GSTM1 gene polymorphism affects the susceptibility to hydroquinone CTD PMID:15141365 PMID:19778234 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 affects response to substance ISO GSTP1 affects the susceptibility to hydroquinone CTD PMID:19778234 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 increases expression
affects response to substance		 ISO hydroquinone results in increased expression of GSTT1 mRNA
GSTT1 affects the susceptibility to hydroquinone		 CTD PMID:19778234 PMID:23290930 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585 		JBrowse link
G Gtpbp2 GTP binding protein 2 increases expression ISO hydroquinone results in increased expression of GTPBP2 mRNA CTD PMID:31256213 NCBI chr 9:14,813,964...14,823,419
Ensembl chr 9:14,813,964...14,823,241 		JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 increases expression ISO hydroquinone results in increased expression of GUCY1B1 mRNA CTD PMID:31256213 NCBI chr 2:167,348,824...167,398,983
Ensembl chr 2:167,348,825...167,398,916 		JBrowse link
G Gvin1 GTPase, very large interferon inducible 1 decreases expression ISO hydroquinone results in decreased expression of GVINP1 mRNA CTD PMID:31256213 NCBI chr 1:160,279,767...160,306,701
Ensembl chr 1:160,277,126...160,306,331 		JBrowse link
G Gypa glycophorin A decreases expression ISO hydroquinone results in decreased expression of GYPA protein CTD PMID:21414390 NCBI chr19:27,450,304...27,465,940
Ensembl chr19:27,450,308...27,465,822 		JBrowse link
G H1f4 H1.4 linker histone, cluster member decreases expression ISO hydroquinone results in decreased expression of H1-4 mRNA CTD PMID:23416264 NCBI chr17:41,486,574...41,487,355
Ensembl chr17:41,486,560...41,487,403 		JBrowse link
G H1f5 H1.5 linker histone, cluster member decreases expression ISO hydroquinone results in decreased expression of H1-5 mRNA CTD PMID:23416264 NCBI chr17:42,726,132...42,727,162
Ensembl chr17:42,726,127...42,769,160 		JBrowse link
G H2ac12 H2A clustered histone 12 decreases expression ISO hydroquinone results in decreased expression of H2AC12 mRNA CTD PMID:23416264 NCBI chr17:42,486,415...42,486,880
Ensembl chr17:42,486,415...42,486,941 		JBrowse link
G H2ac18 H2A clustered histone 18 decreases expression ISO hydroquinone results in decreased expression of H2AC18 mRNA CTD PMID:23416264 NCBI chr 2:183,808,398...183,808,992 JBrowse link
G H2ac20 H2A clustered histone 20 decreases expression ISO hydroquinone results in decreased expression of H2AC20 mRNA CTD PMID:23416264 NCBI chr 2:183,779,879...183,780,357 JBrowse link
G H2ac21 H2A clustered histone 21 decreases expression ISO hydroquinone results in decreased expression of H2AC21 mRNA CTD PMID:23416264 NCBI chr 2:183,779,355...183,779,788 JBrowse link
G H2ax H2A.X variant histone multiple interactions
increases expression
increases phosphorylation
affects localization		 ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of H2AX protein]; 2-tert-butylhydroquinone inhibits the reaction [hydroquinone results in increased expression of H2AX protein]; [ABT-737 co-treated with hydroquinone] results in increased expression of H2AX protein; [E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of H2AX protein modified form; [SIRT1 protein affects the susceptibility to hydroquinone] which affects the expression of H2AX protein; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of H2AX protein]; PARP1 protein affects the reaction [hydroquinone results in increased expression of H2AX protein]; POLH protein affects the reaction [hydroquinone results in increased expression of H2AX protein]; WRN gene mutant form promotes the reaction [hydroquinone results in increased expression of H2AX protein alternative form]; WRN protein affects the reaction [hydroquinone results in increased expression of H2AX protein]
FAU protein affects the reaction [hydroquinone results in increased expression of H2AX protein]
hydroquinone results in increased phosphorylation of H2AX protein
hydroquinone affects the localization of H2AX protein modified form
hydroquinone results in increased expression of H2AX protein; hydroquinone results in increased expression of H2AX protein alternative form		 CTD PMID:17875398 PMID:18835433 PMID:20036648 PMID:21267443 PMID:22687461 More... NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
Ensembl chr 4:44,671,786...44,673,239 		JBrowse link
G H4c14 H4 clustered histone 14 decreases expression ISO hydroquinone results in decreased expression of H4C2 mRNA CTD PMID:23416264 NCBI chr 2:183,831,601...183,831,996
Ensembl chr 2:183,825,994...183,832,048 		JBrowse link
G H4cl1 histone H4C like 1 decreases expression ISO hydroquinone results in decreased expression of H4C6 mRNA CTD PMID:23416264 NCBI chr17:41,368,743...41,426,735 JBrowse link
G H4f3 H1.3 linker histone, cluster member decreases expression ISO hydroquinone results in decreased expression of H1-3 mRNA CTD PMID:23416264 NCBI chr17:41,551,524...41,552,303
Ensembl chr17:41,529,667...41,552,334 		JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 multiple interactions ISO hydroquinone inhibits the reaction [GATA1 protein binds to HBA1 gene] CTD PMID:37329354 NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392
Ensembl chr10:15,307,815...15,338,392 		JBrowse link
G Hbb hemoglobin subunit beta multiple interactions
decreases methylation		 ISO Decitabine inhibits the reaction [hydroquinone inhibits the reaction [Hemin results in increased expression of HBB mRNA]]; hydroquinone inhibits the reaction [Hemin results in increased expression of HBB mRNA]; hydroquinone promotes the reaction [GATA2 protein binds to HBB gene]
hydroquinone results in decreased methylation of HBB promoter		 CTD PMID:21414390 PMID:23973255 PMID:37329354 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Hbb-b1 hemoglobin, beta adult major chain multiple interactions ISO hydroquinone inhibits the reaction [GATA1 protein binds to HBD gene] CTD PMID:37329354 NCBI chr 1:158,224,175...158,231,675
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression ISO hydroquinone results in increased expression of HBEGF mRNA CTD PMID:31256213 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441 		JBrowse link
G Hbg1 hemoglobin subunit gamma 1 multiple interactions ISO hydroquinone inhibits the reaction [GATA1 protein binds to HBG1 gene] CTD PMID:37329354 NCBI chr 1:158,271,871...158,273,426
Ensembl chr 1:158,271,873...158,273,425 		JBrowse link
G Hbp1 HMG-box transcription factor 1 multiple interactions ISO hydroquinone promotes the reaction [GATA2 protein binds to HBP1 gene] CTD PMID:37329354 NCBI chr 6:48,529,633...48,555,775
Ensembl chr 6:48,529,372...48,555,787 		JBrowse link
G Hdac1 histone deacetylase 1 increases expression
multiple interactions		 ISO hydroquinone results in increased expression of HDAC1 mRNA; hydroquinone results in increased expression of HDAC1 protein
trichostatin A inhibits the reaction [hydroquinone results in increased expression of HDAC1 mRNA]		 CTD PMID:27220438 PMID:30448557 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111 		JBrowse link
G Hdac2 histone deacetylase 2 increases expression
multiple interactions		 ISO hydroquinone results in increased expression of HDAC2 mRNA; hydroquinone results in increased expression of HDAC2 protein
trichostatin A inhibits the reaction [hydroquinone results in increased expression of HDAC2 mRNA]		 CTD PMID:27220438 PMID:30448557 NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609 		JBrowse link
G Hdac9 histone deacetylase 9 increases expression ISO hydroquinone results in increased expression of HDAC9 mRNA CTD PMID:31256213 NCBI chr 6:50,762,074...51,624,311
Ensembl chr 6:50,763,590...51,625,333 		JBrowse link
G Hfe homeostatic iron regulator decreases expression ISO hydroquinone results in decreased expression of HFE mRNA CTD PMID:31256213 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502 		JBrowse link
G Hist1h4m histone cluster 1, H4m decreases expression ISO hydroquinone results in decreased expression of H4C1 mRNA CTD PMID:23416264 NCBI chr17:42,698,016...42,698,420
Ensembl chr17:42,698,025...42,698,958 		JBrowse link
G Hjurp Holliday junction recognition protein decreases expression ISO hydroquinone results in decreased expression of HJURP mRNA CTD PMID:23416264 NCBI chr 9:88,853,379...88,867,730
Ensembl chr 9:88,853,386...88,867,728 		JBrowse link
G Hmbs hydroxymethylbilane synthase multiple interactions ISO decitabine inhibits the reaction [hydroquinone inhibits the reaction [Hemin results in increased expression of HMBS mRNA]]; hydroquinone inhibits the reaction [Hemin results in increased expression of HMBS mRNA] CTD PMID:21414390 PMID:23973255 NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957 		JBrowse link
G Hmgb2 high mobility group box 2 decreases expression ISO hydroquinone results in decreased expression of HMGB2 mRNA CTD PMID:23416264 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
Ensembl chr 1:32,710,658...32,713,140 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions		 ISO hydroquinone results in increased expression of HMOX1 mRNA; hydroquinone results in increased expression of HMOX1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [hydroquinone results in increased expression of HMOX1 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; AG 1879 inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; bisindolylmaleimide I inhibits the reaction [hydroquinone results in increased expression of HMOX1 mRNA]; Cysteine inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; Dithiothreitol inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of HMOX1 protein]; SB 203580 inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; Staurosporine inhibits the reaction [hydroquinone results in increased expression of HMOX1 mRNA]; Staurosporine inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; Wortmannin inhibits the reaction [hydroquinone results in increased expression of HMOX1 mRNA]; Wortmannin inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; [Resveratrol co-treated with hydroquinone] results in increased expression of HMOX1 protein; ferric chloride promotes the reaction [hydroquinone results in increased expression of HMOX1 protein]; NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of HMOX1 protein]; Resveratrol promotes the reaction [hydroquinone results in increased expression of HMOX1 mRNA]; risuteganib promotes the reaction [hydroquinone results in increased expression of HMOX1 mRNA]; risuteganib promotes the reaction [hydroquinone results in increased expression of HMOX1 protein]; S-allylcysteine inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]		 CTD PMID:17464197 PMID:21059386 PMID:23290930 PMID:28645578 PMID:29508652 More... NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hotairm1 Hoxa transcript antisense RNA, myeloid-specific 1 multiple interactions
affects expression
affects methylation		 ISO Decitabine affects the reaction [hydroquinone affects the expression of HOTAIRM1 mRNA]; Decitabine affects the reaction [hydroquinone affects the methylation of HOTAIRM1 promoter]; trichostatin A affects the reaction [hydroquinone affects the expression of HOTAIRM1 mRNA]; trichostatin A affects the reaction [hydroquinone affects the methylation of HOTAIRM1 promoter] CTD PMID:31899212 NCBI chr 4:81,258,793...81,262,291 JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions
affects expression		 ISO 3-aminobenzamide inhibits the reaction [hydroquinone results in increased expression of HRAS protein]; Doxorubicin inhibits the reaction [hydroquinone results in decreased expression of HRAS protein]; hydroquinone promotes the reaction [PARP1 protein binds to and results in increased ADP-ribosylation of and results in increased expression of HRAS protein]; PARP1 protein promotes the reaction [hydroquinone results in increased expression of HRAS protein]
hydroquinone affects the expression of HRAS mRNA; hydroquinone affects the expression of HRAS protein		 CTD PMID:26047893 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 increases expression ISO hydroquinone results in increased expression of HSD17B2 mRNA CTD PMID:31256213 NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202 		JBrowse link
G Hspa13 heat shock protein family A (Hsp70) member 13 increases expression ISO hydroquinone results in increased expression of HSPA13 mRNA CTD PMID:31256213 NCBI chr11:14,375,669...14,389,853
Ensembl chr11:14,373,275...14,389,895 		JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 increases expression ISO hydroquinone results in increased expression of HSPA2 mRNA CTD PMID:15452088 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions		 ISO hydroquinone results in increased expression of HSPA5 protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of HSPA5 protein]		 CTD PMID:24053669 PMID:36646296 PMID:37148176 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A decreases expression ISO hydroquinone results in decreased expression of HTR1A protein CTD PMID:27606422 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B decreases expression ISO hydroquinone results in decreased expression of HTR1B protein CTD PMID:27606422 NCBI chr 8:82,513,572...82,534,670
Ensembl chr 8:82,517,360...82,534,549 		JBrowse link
G Hyls1 HYLS1, centriolar and ciliogenesis associated decreases expression ISO hydroquinone results in decreased expression of HYLS1 mRNA CTD PMID:23416264 NCBI chr 8:33,912,692...33,921,760
Ensembl chr 8:33,912,692...33,921,760 		JBrowse link
G Id1 inhibitor of DNA binding 1 increases expression ISO hydroquinone results in increased expression of ID1 mRNA CTD PMID:31256213 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419 		JBrowse link
G Id3 inhibitor of DNA binding 3 decreases expression ISO hydroquinone results in decreased expression of ID3 mRNA CTD PMID:31256213 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349 		JBrowse link
G Id4 inhibitor of DNA binding 4 increases expression ISO hydroquinone results in increased expression of ID4 mRNA CTD PMID:31256213 NCBI chr17:16,389,387...16,391,956
Ensembl chr17:16,389,387...16,392,470 		JBrowse link
G Ier3 immediate early response 3 increases expression ISO hydroquinone results in increased expression of IER3 mRNA CTD PMID:31256213 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583 		JBrowse link
G Ifi44 interferon-induced protein 44 decreases expression ISO hydroquinone results in decreased expression of IFI44 mRNA CTD PMID:31256213 NCBI chr 2:240,626,058...240,643,879
Ensembl chr 2:240,626,066...240,643,844 		JBrowse link
G Ifi44l interferon-induced protein 44-like decreases expression ISO hydroquinone results in decreased expression of IFI44L mRNA CTD PMID:31256213 NCBI chr 2:240,668,742...240,706,425
Ensembl chr 2:240,668,713...240,706,359 		JBrowse link
G Ifih1 interferon induced with helicase C domain 1 decreases expression ISO hydroquinone results in decreased expression of IFIH1 mRNA CTD PMID:31256213 NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456 		JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 decreases expression ISO hydroquinone results in decreased expression of IFIT3 mRNA CTD PMID:31256213 NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307 		JBrowse link
G Ifitm1 interferon induced transmembrane protein 1 decreases expression ISO hydroquinone results in decreased expression of IFITM1 mRNA CTD PMID:31256213 NCBI chr 1:196,067,163...196,069,169
Ensembl chr 1:196,067,963...196,069,169 		JBrowse link
G Ifng interferon gamma multiple interactions ISO hydroquinone inhibits the reaction [[IFNG protein co-treated with lipopolysaccharide, E. coli O26-B6] results in increased secretion of CCL2 protein]; hydroquinone inhibits the reaction [Amino Acids, Peptides, and Proteins results in increased expression of IFNG protein]; IFNG protein promotes the reaction [[Lipopolysaccharides co-treated with hydroquinone] results in increased abundance of Nitric Oxide] CTD PMID:3137358 PMID:7884313 PMID:22465845 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Ifrd1 interferon-related developmental regulator 1 increases expression ISO hydroquinone results in increased expression of IFRD1 mRNA CTD PMID:31256213 NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990 		JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO IGF1 protein inhibits the reaction [hydroquinone results in decreased expression of CTNNB1 protein]; IGF1 protein inhibits the reaction [hydroquinone results in decreased phosphorylation of GSK3B protein]; IGF1 protein inhibits the reaction [hydroquinone results in increased expression of CASP3 protein modified form] CTD PMID:28886972 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 decreases expression ISO hydroquinone results in decreased expression of IGFBP3 mRNA CTD PMID:31256213 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of IKBKB protein] CTD PMID:20054000 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250 		JBrowse link
G Il10 interleukin 10 multiple interactions
increases secretion		 ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 mRNA]
hydroquinone results in increased secretion of IL10 protein
hydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein]		 CTD PMID:17464197 PMID:17572062 PMID:23559866 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il12b interleukin 12B multiple interactions
increases expression		 ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]
hydroquinone results in increased expression of IL12B mRNA		 CTD PMID:15894107 PMID:17464197 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il15 interleukin 15 decreases secretion ISO hydroquinone results in decreased secretion of IL15 protein CTD PMID:23559866 NCBI chr19:25,640,025...25,706,818
Ensembl chr19:25,640,251...25,706,820 		JBrowse link
G Il17a interleukin 17A increases secretion EXP hydroquinone results in increased secretion of IL17A protein CTD PMID:29935983 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889 		JBrowse link
G Il18 interleukin 18 multiple interactions
increases secretion		 ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased secretion of IL18 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased secretion of IL18 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased secretion of IL18 protein] CTD PMID:36646296 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions
increases expression
decreases cleavage		 ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased cleavage of IL1A protein]
Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of IL1A protein]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of IL1A protein]]; PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of IL1A protein]
hydroquinone results in increased expression of IL1A mRNA; hydroquinone results in increased expression of IL1A protein
hydroquinone results in decreased cleavage of IL1A protein		 CTD PMID:1868253 PMID:8548860 PMID:9118901 PMID:28836394 PMID:31256213 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta decreases cleavage
multiple interactions
increases expression
decreases secretion		 ISO
EXP		 hydroquinone results in decreased cleavage of IL1B protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of and results in increased secretion of IL1B protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of and results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of and results in increased secretion of IL1B protein]; hydroquinone results in increased expression of and results in increased secretion of IL1B protein
hydroquinone results in increased expression of IL1B mRNA
hydroquinone results in decreased secretion of IL1B protein
[KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of IL1B mRNA; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]
[COL2A1 protein co-treated with Freund's Adjuvant co-treated with hydroquinone] results in increased secretion of IL1B protein; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]		 CTD PMID:8548860 PMID:9118901 PMID:17464197 PMID:19148301 PMID:22717997 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1f10 interleukin 1 family member 10 increases expression ISO hydroquinone results in increased expression of IL1F10 mRNA CTD PMID:31256213 NCBI chr 3:7,072,511...7,075,439
Ensembl chr 3:7,072,511...7,075,439 		JBrowse link
G Il1rn interleukin 1 receptor antagonist increases secretion ISO hydroquinone results in increased secretion of IL1RN protein CTD PMID:23559866 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Il2 interleukin 2 multiple interactions ISO hydroquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 protein] CTD PMID:9571986 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il23a interleukin 23 subunit alpha multiple interactions ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL23A mRNA] CTD PMID:17464197 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923 		JBrowse link
G Il33 interleukin 33 decreases expression ISO hydroquinone results in decreased expression of IL33 mRNA CTD PMID:31256213 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Il36g interleukin 36, gamma increases expression ISO hydroquinone results in increased expression of IL36G mRNA CTD PMID:31256213 NCBI chr 3:6,948,323...6,954,485
Ensembl chr 3:6,948,297...6,954,480 		JBrowse link
G Il36rn interleukin 36 receptor antagonist increases expression ISO hydroquinone results in increased expression of IL36RN mRNA CTD PMID:31256213 NCBI chr 3:7,044,419...7,051,016
Ensembl chr 3:7,044,406...7,051,016 		JBrowse link
G Il4 interleukin 4 multiple interactions ISO hydroquinone promotes the reaction [keyhole-limpet hemocyanin results in increased expression of IL4 mRNA]; hydroquinone promotes the reaction [keyhole-limpet hemocyanin results in increased expression of IL4 protein] CTD PMID:12153512 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il6 interleukin 6 multiple interactions
decreases secretion		 EXP
ISO		 [COL2A1 protein co-treated with hydroquinone] results in increased expression of IL6 protein; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
[hydroquinone co-treated with TNF protein] results in increased secretion of IL6 protein
hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
hydroquinone results in decreased secretion of IL6 protein		 CTD PMID:17464197 PMID:19148301 PMID:20054000 PMID:22302391 PMID:22717997 More... NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Inhba inhibin subunit beta A increases expression ISO hydroquinone results in increased expression of INHBA mRNA CTD PMID:31256213 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982 		JBrowse link
G Inhbe inhibin subunit beta E decreases expression ISO hydroquinone results in decreased expression of INHBE mRNA CTD PMID:29221148 NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172 		JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase type II B increases expression ISO hydroquinone results in increased expression of INPP4B mRNA CTD PMID:31256213 NCBI chr19:25,920,189...26,670,085
Ensembl chr19:25,925,358...26,280,634 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 decreases expression ISO hydroquinone results in decreased expression of IRAK1 mRNA CTD PMID:30090394 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521 		JBrowse link
G Irf3 interferon regulatory factor 3 multiple interactions ISO hydroquinone inhibits the reaction [AKT1 protein results in increased phosphorylation of IRF3 protein]; hydroquinone inhibits the reaction [AKT2 protein results in increased phosphorylation of IRF3 protein]; hydroquinone inhibits the reaction [AKT3 protein results in increased phosphorylation of IRF3 protein]; hydroquinone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of IRF3 protein]; hydroquinone inhibits the reaction [TICAM1 protein results in increased phosphorylation of IRF3 protein] CTD PMID:28883758 NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935 		JBrowse link
G Irs1 insulin receptor substrate 1 decreases expression ISO hydroquinone results in decreased expression of IRS1 mRNA CTD PMID:31256213 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier decreases expression ISO hydroquinone results in decreased expression of ISG15 mRNA CTD PMID:31256213 NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435 		JBrowse link
G Itgb1 integrin subunit beta 1 decreases activity
decreases expression		 ISO hydroquinone results in decreased activity of ITGB1 protein
hydroquinone results in decreased expression of ITGB1 mRNA
hydroquinone results in decreased expression of ITGB1 protein		 CTD PMID:17464197 PMID:19148301 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Itgb2 integrin subunit beta 2 decreases expression
increases expression		 ISO hydroquinone results in decreased expression of ITGB2 protein
hydroquinone results in decreased expression of ITGB2 mRNA
hydroquinone results in increased expression of ITGB2 protein		 CTD PMID:17464197 PMID:19148301 PMID:21664406 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600 		JBrowse link
G Itgb3 integrin subunit beta 3 increases expression ISO hydroquinone results in increased expression of ITGB3 protein CTD PMID:21664406 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
G Ivl involucrin increases expression ISO hydroquinone results in increased expression of IVL mRNA; hydroquinone results in increased expression of IVL protein CTD PMID:25240866 PMID:31256213 NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100 		JBrowse link
G Jag1 jagged canonical Notch ligand 1 decreases expression ISO hydroquinone results in decreased expression of JAG1 mRNA CTD PMID:22960397 NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209 		JBrowse link
G Jchain joining chain of multimeric IgA and IgM decreases expression ISO hydroquinone results in decreased expression of JCHAIN mRNA CTD PMID:29221148 NCBI chr14:19,538,927...19,547,023
Ensembl chr14:19,538,952...19,546,298 		JBrowse link
G Jrk Jrk helix-turn-helix protein decreases expression ISO hydroquinone results in decreased expression of JRK mRNA CTD PMID:31256213 NCBI chr 7:106,590,662...106,595,345
Ensembl chr 7:106,589,484...106,596,371 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit affects localization
multiple interactions
increases phosphorylation		 ISO hydroquinone affects the localization of JUN protein
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in increased phosphorylation of JUN protein]; hydroquinone promotes the reaction [JUN protein binds to MIR122 promoter]; hydroquinone promotes the reaction [JUN protein binds to PPP2CA promoter]; JUN protein affects the reaction [hydroquinone results in decreased expression of MIR122 mRNA]; JUN protein affects the reaction [hydroquinone results in increased expression of ADAM17 mRNA]; JUN protein affects the reaction [hydroquinone results in increased expression of ADAM17 protein]; JUN protein affects the reaction [hydroquinone results in increased expression of PPP2CA protein]; JUN protein affects the reaction [hydroquinone results in increased expression of TNF protein]; pyrazolanthrone inhibits the reaction [hydroquinone results in increased phosphorylation of JUN protein]		 CTD PMID:23288922 PMID:23791922 PMID:26807887 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kbtbd6 kelch repeat and BTB domain containing 6 decreases expression ISO hydroquinone results in decreased expression of KBTBD6 mRNA CTD PMID:31256213 NCBI chr15:54,848,285...54,850,042
Ensembl chr15:54,848,446...54,850,453 		JBrowse link
G Kbtbd7 kelch repeat and BTB domain containing 7 decreases expression ISO hydroquinone results in decreased expression of KBTBD7 mRNA CTD PMID:31256213 NCBI chr15:54,806,878...54,811,457
Ensembl chr15:54,806,873...54,811,687 		JBrowse link
G Kcnj15 potassium inwardly-rectifying channel, subfamily J, member 15 decreases expression ISO hydroquinone results in decreased expression of KCNJ15 mRNA CTD PMID:31256213 NCBI chr11:34,577,397...34,621,725
Ensembl chr11:34,577,363...34,621,952 		JBrowse link
G Kdm6a lysine demethylase 6A decreases expression ISO hydroquinone results in decreased expression of KDM6A mRNA CTD PMID:31256213 NCBI chr  X:4,337,466...4,477,100
Ensembl chr  X:4,337,750...4,477,062 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 decreases expression ISO hydroquinone results in decreased expression of KEAP1 protein CTD PMID:23290930 PMID:36646296 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Kics2 KICSTOR subunit 2 decreases expression ISO hydroquinone results in decreased expression of KICS2 mRNA CTD PMID:31256213 NCBI chr 7:57,284,213...57,299,070
Ensembl chr 7:57,284,192...57,297,486 		JBrowse link
G Kif18a kinesin family member 18A decreases expression ISO hydroquinone results in decreased expression of KIF18A mRNA CTD PMID:23416264 NCBI chr 3:95,764,388...95,824,756
Ensembl chr 3:95,764,388...95,824,582 		JBrowse link
G Kitlg KIT ligand increases expression ISO hydroquinone results in increased expression of KITLG mRNA CTD PMID:22960397 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214 		JBrowse link
G Klf2 KLF transcription factor 2 increases expression ISO hydroquinone results in increased expression of KLF2 mRNA CTD PMID:31256213 NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944 		JBrowse link
G Klf4 KLF transcription factor 4 multiple interactions ISO [KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of KLF4 mRNA CTD PMID:37245849 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602 		JBrowse link
G Klf7 KLF transcription factor 7 increases expression ISO hydroquinone results in increased expression of KLF7 mRNA CTD PMID:31256213 NCBI chr 9:65,433,683...65,526,372
Ensembl chr 9:65,437,167...65,526,261 		JBrowse link
G Klhl31 kelch-like family member 31 decreases expression ISO hydroquinone results in decreased expression of KLHL31 mRNA CTD PMID:31256213 NCBI chr 8:78,515,514...78,538,873
Ensembl chr 8:78,515,514...78,538,873 		JBrowse link
G Klk6 kallikrein related-peptidase 6 increases expression ISO hydroquinone results in increased expression of KLK6 mRNA CTD PMID:31256213 NCBI chr 1:94,278,863...94,286,136
Ensembl chr 1:94,280,340...94,286,121 		JBrowse link
G Klrg2 killer cell lectin like receptor G2 decreases expression ISO hydroquinone results in decreased expression of KLRG2 mRNA CTD PMID:31256213 NCBI chr 4:67,360,216...67,374,867
Ensembl chr 4:67,363,919...67,374,147 		JBrowse link
G Kmt2a lysine methyltransferase 2A decreases response to substance
multiple interactions		 ISO KMT2A mutant form results in decreased susceptibility to hydroquinone
[KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of APP mRNA; [KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of FABP4 mRNA; [KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of IL1B mRNA; [KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of KLF4 mRNA; [KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of LPL mRNA; [KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of PPARG mRNA		 CTD PMID:37245849 NCBI chr 8:45,116,763...45,193,320
Ensembl chr 8:45,118,814...45,193,181 		JBrowse link
G Kras KRAS proto-oncogene, GTPase multiple interactions
increases expression
affects expression		 ISO [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of KRAS protein
hydroquinone results in increased expression of KRAS protein
hydroquinone affects the expression of KRAS mRNA		 CTD PMID:27515134 PMID:28444915 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Krt13 keratin 13 decreases expression ISO hydroquinone results in decreased expression of KRT13 mRNA CTD PMID:31256213 NCBI chr10:85,051,887...85,056,099
Ensembl chr10:85,051,889...85,056,084 		JBrowse link
G Krt19 keratin 19 decreases expression ISO hydroquinone results in decreased expression of KRT19 mRNA CTD PMID:31256213 NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799 		JBrowse link
G Krt23 keratin 23 increases expression ISO hydroquinone results in increased expression of KRT23 mRNA CTD PMID:31256213 NCBI chr10:84,434,445...84,450,773
Ensembl chr10:84,434,380...84,450,983 		JBrowse link
G Krt24 keratin 24 decreases expression ISO hydroquinone results in decreased expression of KRT24 mRNA CTD PMID:31256213 NCBI chr10:84,232,163...84,237,299
Ensembl chr10:84,232,164...84,237,299 		JBrowse link
G Krt78 keratin 78 increases expression ISO hydroquinone results in increased expression of KRT78 mRNA CTD PMID:31256213 NCBI chr 7:133,074,193...133,081,536
Ensembl chr 7:133,074,215...133,082,021 		JBrowse link
G Krt80 keratin 80 increases expression ISO hydroquinone results in increased expression of KRT80 mRNA CTD PMID:31256213 NCBI chr 7:132,463,216...132,485,134
Ensembl chr 7:132,463,218...132,485,508 		JBrowse link
G Lama4 laminin subunit alpha 4 increases expression
multiple interactions		 ISO hydroquinone results in increased expression of LAMA4 protein
[TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein]		 CTD PMID:18055817 NCBI chr20:42,392,268...42,533,347
Ensembl chr20:42,392,268...42,533,347 		JBrowse link
G Lasp1 LIM and SH3 protein 1 affects expression ISO hydroquinone affects the expression of LASP1 protein CTD PMID:20021034 NCBI chr10:82,795,177...82,835,659
Ensembl chr10:82,795,137...82,943,292 		JBrowse link
G Lcn2 lipocalin 2 increases expression ISO hydroquinone results in increased expression of LCN2 mRNA CTD PMID:31256213 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Lef1 lymphoid enhancer binding factor 1 multiple interactions
decreases expression		 ISO hydroquinone inhibits the reaction [CTNNB1 protein binds to LEF1 protein]
hydroquinone results in decreased expression of LEF1 protein		 CTD PMID:28886972 NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794 		JBrowse link
G Lemd1 LEM domain containing 1 decreases expression ISO hydroquinone results in decreased expression of LEMD1 mRNA CTD PMID:31256213 NCBI chr13:43,631,705...43,697,765
Ensembl chr13:43,665,926...43,697,948 		JBrowse link
G Lgals9 galectin 9 increases expression ISO hydroquinone results in increased expression of LGALS9 mRNA CTD PMID:29221148 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Lgalsl galectin-like increases expression ISO hydroquinone results in increased expression of LGALSL mRNA CTD PMID:31256213 NCBI chr14:94,996,991...95,004,499
Ensembl chr14:94,996,990...95,004,980 		JBrowse link
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 decreases expression ISO hydroquinone results in decreased expression of LGR4 mRNA CTD PMID:31256213 NCBI chr 3:96,447,385...96,550,006
Ensembl chr 3:96,447,858...96,548,899 		JBrowse link
G Lipg lipase G, endothelial type increases expression ISO hydroquinone results in increased expression of LIPG mRNA CTD PMID:31256213 NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260 		JBrowse link
G Lmna lamin A/C affects expression ISO hydroquinone affects the expression of LMNA protein CTD PMID:17181942 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423 		JBrowse link
G Loricrin loricrin cornified envelope precursor protein increases expression ISO hydroquinone results in increased expression of LORICRIN mRNA
hydroquinone results in increased expression of LORICRIN protein		 CTD PMID:25240866 PMID:31256213 NCBI chr 2:177,558,062...177,560,960
Ensembl chr 2:177,558,252...177,559,807 		JBrowse link
G Lpl lipoprotein lipase multiple interactions ISO [KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of LPL mRNA CTD PMID:37245849 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249 		JBrowse link
G Lrrc27 leucine rich repeat containing 27 decreases expression ISO hydroquinone results in decreased expression of LRRC27 mRNA CTD PMID:31256213 NCBI chr 1:194,004,967...194,035,087
Ensembl chr 1:194,005,182...194,035,084 		JBrowse link
G Lrrc71 leucine rich repeat containing 71 increases expression ISO hydroquinone results in increased expression of LRRC71 mRNA CTD PMID:29221148 NCBI chr 2:173,194,792...173,207,448
Ensembl chr 2:173,194,792...173,207,448 		JBrowse link
G Lrriq3 leucine-rich repeats and IQ motif containing 3 decreases expression ISO hydroquinone results in decreased expression of LRRIQ3 mRNA CTD PMID:31256213 NCBI chr 2:244,119,975...244,214,590
Ensembl chr 2:244,126,200...244,212,339 		JBrowse link
G Lss lanosterol synthase decreases expression ISO hydroquinone results in decreased expression of LSS mRNA CTD PMID:31256213 NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762 		JBrowse link
G Ly6e lymphocyte antigen 6 family member E decreases expression ISO hydroquinone results in decreased expression of LY6E mRNA CTD PMID:31256213 NCBI chr 7:106,935,530...106,939,689
Ensembl chr 7:106,935,761...106,939,689 		JBrowse link
G Ly96 lymphocyte antigen 96 increases expression ISO hydroquinone results in increased expression of LY96 mRNA CTD PMID:31256213 NCBI chr 5:2,582,233...2,612,357
Ensembl chr 5:2,582,254...2,612,386 		JBrowse link
G Lypd5 Ly6/Plaur domain containing 5 increases expression ISO hydroquinone results in increased expression of LYPD5 mRNA CTD PMID:31256213 NCBI chr 1:79,929,818...79,941,791
Ensembl chr 1:79,935,240...79,941,039 		JBrowse link
G Macroh2a1 macroH2A.1 histone decreases expression ISO hydroquinone results in decreased expression of MACROH2A1 protein CTD PMID:35698848 NCBI chr17:8,479,331...8,542,071
Ensembl chr17:8,479,372...8,542,072 		JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO hydroquinone results in increased expression of MAFF mRNA CTD PMID:31256213 NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851 		JBrowse link
G Magi1 membrane associated guanylate kinase, WW and PDZ domain containing 1 multiple interactions ISO [hydroquinone co-treated with Hemin] affects the expression of MAGI1 mRNA; [hydroquinone co-treated with Hemin] affects the expression of MAGI1 protein; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A protein]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 protein]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RASSF5 mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RASSF5 protein] CTD PMID:32198055 NCBI chr 4:126,205,663...126,811,354
Ensembl chr 4:126,206,816...126,811,691 		JBrowse link
G Map1b microtubule-associated protein 1B increases expression ISO hydroquinone results in increased expression of MAP1B mRNA CTD PMID:31256213 NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha multiple interactions ISO Chloroquine inhibits the reaction [hydroquinone results in increased degradation of MAP1LC3A protein]; hydroquinone affects the localization of and results in increased degradation of MAP1LC3A protein CTD PMID:35302183 NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases lipidation
multiple interactions		 ISO hydroquinone results in increased lipidation of MAP1LC3B protein
4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine inhibits the reaction [hydroquinone results in increased lipidation of MAP1LC3B protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased lipidation of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased lipidation of MAP1LC3B protein]; ATF6 protein affects the reaction [hydroquinone results in increased lipidation of MAP1LC3B protein]; Chloroquine promotes the reaction [hydroquinone results in increased lipidation of MAP1LC3B protein]; Sirolimus promotes the reaction [hydroquinone results in increased lipidation of MAP1LC3B protein]		 CTD PMID:37148176 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
Ensembl chr16:49,665,791...49,677,690 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions ISO MAP2K1 protein inhibits the reaction [hydroquinone results in decreased phosphorylation of MAPK1 protein]; MAP2K1 protein inhibits the reaction [hydroquinone results in decreased phosphorylation of MAPK3 protein]; MAP2K1 protein inhibits the reaction [hydroquinone results in increased expression of PPP2CA protein] CTD PMID:23288922 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Map7d2 MAP7 domain containing 2 decreases expression ISO hydroquinone results in decreased expression of MAP7D2 mRNA CTD PMID:31256213 NCBI chr  X:35,372,453...35,488,073
Ensembl chr  X:35,372,700...35,488,091 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
decreases phosphorylation		 ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [hydroquinone results in increased phosphorylation of and results in increased activity of MAPK1 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in decreased phosphorylation of MAPK1 protein]; [CSF2 protein co-treated with hydroquinone] results in increased phosphorylation of and results in increased activity of MAPK1 protein; [venetoclax co-treated with WEHI-539 co-treated with hydroquinone] results in decreased phosphorylation of MAPK1 protein; hydroquinone results in increased phosphorylation of and results in increased activity of MAPK1 protein; MAP2K1 protein inhibits the reaction [hydroquinone results in decreased phosphorylation of MAPK1 protein]
hydroquinone results in increased phosphorylation of MAPK1 protein		 CTD PMID:15129224 PMID:23288922 PMID:23290930 PMID:23791922 PMID:35561756 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions
increases phosphorylation		 ISO Chloroquine inhibits the reaction [hydroquinone results in increased phosphorylation of MAPK14 protein] CTD PMID:35302183 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
decreases phosphorylation		 ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [hydroquinone results in increased phosphorylation of and results in increased activity of MAPK3 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in decreased phosphorylation of MAPK3 protein]; [CSF2 protein co-treated with hydroquinone] results in increased phosphorylation of and results in increased activity of MAPK3 protein; [venetoclax co-treated with WEHI-539 co-treated with hydroquinone] results in decreased phosphorylation of MAPK3 protein; hydroquinone results in increased phosphorylation of and results in increased activity of MAPK3 protein; MAP2K1 protein inhibits the reaction [hydroquinone results in decreased phosphorylation of MAPK3 protein]
hydroquinone results in increased phosphorylation of MAPK3 protein		 CTD PMID:15129224 PMID:23288922 PMID:23290930 PMID:23791922 PMID:35561756 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation
multiple interactions		 ISO hydroquinone results in increased phosphorylation of MAPK8 protein
hydroquinone results in decreased expression of and results in increased phosphorylation of MAPK8 protein		 CTD PMID:23791922 PMID:37148176 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Marchf3 membrane associated ring-CH-type finger 3 increases expression ISO hydroquinone results in increased expression of MARCHF3 mRNA CTD PMID:31256213 NCBI chr18:50,237,218...50,389,343
Ensembl chr18:50,237,230...50,389,150 		JBrowse link
G Mbd2 methyl-CpG binding domain protein 2 decreases expression
multiple interactions
increases expression		 ISO hydroquinone results in decreased expression of MBD2 mRNA
PARP1 protein affects the reaction [hydroquinone results in increased expression of MBD2 protein]		 CTD PMID:22245671 PMID:30448557 NCBI chr18:64,174,002...64,240,795
Ensembl chr18:64,174,002...64,240,794 		JBrowse link
G Mbnl3 muscleblind-like splicing regulator 3 decreases expression ISO hydroquinone results in decreased expression of MBNL3 mRNA CTD PMID:31256213 NCBI chr  X:130,641,942...130,737,179
Ensembl chr  X:130,648,538...130,737,056 		JBrowse link
G Mboat2 membrane bound O-acyltransferase domain containing 2 increases expression ISO hydroquinone results in increased expression of MBOAT2 mRNA CTD PMID:31256213 NCBI chr 6:41,471,135...41,597,599
Ensembl chr 6:41,471,161...41,593,485 		JBrowse link
G Mc1r melanocortin 1 receptor decreases expression ISO hydroquinone results in decreased expression of MC1R mRNA CTD PMID:23738040 NCBI chr19:51,452,448...51,455,375
Ensembl chr19:51,453,239...51,454,192 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member increases expression
multiple interactions		 ISO hydroquinone results in increased expression of MCL1 protein
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of MCL1 protein]; [hydroquinone co-treated with WEHI-539] results in decreased expression of MCL1 protein; [WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of MCL1 protein; PMAIP1 protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of MCL1 protein]; SP1 protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of MCL1 protein]		 CTD PMID:35561756 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Mctp1 multiple C2 and transmembrane domain containing 1 increases expression ISO hydroquinone results in increased expression of MCTP1 mRNA CTD PMID:31256213 NCBI chr 2:6,071,408...6,761,833
Ensembl chr 2:6,065,808...6,761,833 		JBrowse link
G Mctp2 multiple C2 and transmembrane domain containing 2 decreases expression ISO hydroquinone results in decreased expression of MCTP2 mRNA CTD PMID:31256213 NCBI chr 1:125,769,932...126,002,886
Ensembl chr 1:125,771,233...126,002,928 		JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO hydroquinone results in increased expression of MDM2 mRNA CTD PMID:29221148 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mettl21a methyltransferase 21A, HSPA lysine decreases expression ISO hydroquinone results in decreased expression of METTL21A mRNA CTD PMID:31256213 NCBI chr 9:65,934,253...65,999,964
Ensembl chr 9:65,978,051...65,987,550 		JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases expression ISO hydroquinone results in increased expression of MGST1 mRNA CTD PMID:15452088 NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892 		JBrowse link
G Mid1 midline 1 decreases expression ISO