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G |
Aif1 |
allograft inflammatory factor 1 |
multiple interactions |
ISO |
sophoricoside inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of AIF1 protein] |
CTD |
PMID:37741537 |
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NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions |
ISO |
dorsomorphin inhibits the reaction [sophoricoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of BAX protein]]; Sirolimus inhibits the reaction [sophoricoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of BAX protein]]; sophoricoside inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of BAX protein]; sophoricoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of BAX protein] |
CTD |
PMID:37741537 |
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions |
ISO |
dorsomorphin inhibits the reaction [sophoricoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of BCL2 protein]]; Sirolimus inhibits the reaction [sophoricoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of BCL2 protein]]; sophoricoside inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of BCL2 protein]; sophoricoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of BCL2 protein] |
CTD |
PMID:37741537 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Casp3 |
caspase 3 |
multiple interactions |
ISO |
sophoricoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased cleavage of CASP3 protein] |
CTD |
PMID:37741537 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Cdh1 |
cadherin 1 |
decreases expression |
ISO |
sophoricoside results in decreased expression of CDH1 |
CTD |
PMID:24877640 |
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NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
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G |
Esr1 |
estrogen receptor 1 |
decreases expression |
ISO |
sophoricoside results in decreased expression of ESR1 |
CTD |
PMID:24877640 |
|
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Il6 |
interleukin 6 |
multiple interactions |
ISO |
sophoricoside inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of IL6 mRNA]; sophoricoside inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; sophoricoside inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein] |
CTD |
PMID:37741537 |
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Itgb3 |
integrin subunit beta 3 |
decreases expression |
ISO |
sophoricoside results in decreased expression of ITGB3 |
CTD |
PMID:24877640 |
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NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
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G |
Mmp2 |
matrix metallopeptidase 2 |
decreases expression |
ISO |
sophoricoside results in decreased expression of MMP2 |
CTD |
PMID:24877640 |
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NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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G |
Mtor |
mechanistic target of rapamycin kinase |
multiple interactions |
ISO |
sophoricoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased phosphorylation of MTOR protein] |
CTD |
PMID:37741537 |
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NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions |
ISO |
sophoricoside inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of and results in increased phosphorylation of NFKBIA protein]; sophoricoside inhibits the reaction [Lipopolysaccharides results in decreased expression of and results in increased phosphorylation of NFKBIA protein] |
CTD |
PMID:37741537 |
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NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
ISO |
sophoricoside inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of NOS2 mRNA]; sophoricoside inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; sophoricoside inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] |
CTD |
PMID:37741537 |
|
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Pgr |
progesterone receptor |
increases expression |
ISO |
sophoricoside results in increased expression of PGR |
CTD |
PMID:24877640 |
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NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO |
sophoricoside inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of PTGS2 mRNA]; sophoricoside inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; sophoricoside inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] |
CTD |
PMID:37741537 |
|
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
sophoricoside inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased phosphorylation of RELA protein]; sophoricoside inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein] |
CTD |
PMID:37741537 |
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Th |
tyrosine hydroxylase |
multiple interactions |
ISO |
sophoricoside inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH protein] |
CTD |
PMID:37741537 |
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NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
sophoricoside inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of TNF mRNA]; sophoricoside inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; sophoricoside inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] |
CTD |
PMID:37741537 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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