CHEBI ONTOLOGY - ANNOTATIONS |
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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
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Term: | glycopeptide |
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Accession: | CHEBI:24396
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browse the term
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Definition: | Any carbohydrate derivative that consists of glycan moieties covalently attached to the side chains of the amino acid residues that constitute the peptide. |
Synonyms: | exact_synonym: | glycopeptides |
| alt_id: | CHEBI:24395; CHEBI:5478 |
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Abca3 |
ATP binding cassette subfamily A member 3 |
decreases expression |
EXP |
Bleomycin results in decreased expression of ABCA3 mRNA; Bleomycin results in decreased expression of ABCA3 protein |
CTD |
PMID:34425168 |
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NCBI chr10:13,382,439...13,439,748
Ensembl chr10:13,382,540...13,439,745
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Ace |
angiotensin I converting enzyme |
multiple interactions decreases expression |
EXP |
angiotensin I (1-7) inhibits the reaction [Bleomycin results in decreased expression of ACE protein] |
CTD |
PMID:20581171 |
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NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
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Ace2 |
angiotensin converting enzyme 2 |
multiple interactions decreases expression |
EXP |
angiotensin I (1-7) inhibits the reaction [Bleomycin results in decreased expression of ACE2 mRNA] |
CTD |
PMID:20581171 |
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NCBI chr X:30,293,597...30,340,961
Ensembl chr X:30,293,589...30,340,977
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Acta2 |
actin alpha 2, smooth muscle |
increases expression multiple interactions decreases expression |
ISO EXP |
Bleomycin results in increased expression of ACTA2 mRNA; Bleomycin results in increased expression of ACTA2 protein Ephedrine inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; Ephedrine inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; yupingfeng inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; yupingfeng inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein] Bleomycin results in decreased expression of ACTA2 protein allyl sulfide inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; andrographolide inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; montelukast inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; pachymic acid inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; protocatechualdehyde inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein] (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of and results in increased phosphorylation of ACTA2 protein]; 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; 5-hydroxydecanoic acid inhibits the reaction [Diazoxide inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]]; [Arsenic Trioxide co-treated with Bleomycin] results in decreased expression of ACTA2 mRNA; [Bleomycin co-treated with Soot] results in increased expression of ACTA2 protein; Bleomycin results in increased expression of and results in increased phosphorylation of ACTA2 protein; Calcitriol inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; celastrol inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of and results in increased phosphorylation of ACTA2 protein]; Diazoxide inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; honokiol inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; icaritin inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; loganin inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; loganin inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; MIR100HG mRNA affects the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; MIR100HG mRNA affects the reaction [Bleomycin results in increased expression of ACTA2 protein]; morroniside inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; morroniside inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; Thioctic Acid inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA] |
CTD |
PMID:14609568 PMID:17177178 PMID:21381050 PMID:23656969 PMID:24762191 PMID:25582705 PMID:25648892 PMID:26520185 PMID:27153807 PMID:27704718 PMID:28694203 PMID:31302203 PMID:31706003 PMID:31901889 PMID:32032644 PMID:34153405 PMID:34425168 PMID:35187969 PMID:35267148 PMID:35279615 PMID:35472619 PMID:35716765 PMID:37163307 PMID:37399107 PMID:37778983 PMID:37783230 PMID:37898439 More...
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NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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Actg1 |
actin, gamma 1 |
increases expression |
ISO |
Bleomycin results in increased expression of ACTG1 mRNA |
CTD |
PMID:36087614 |
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NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232 Ensembl chr 3:105,619,737...105,624,232
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Actn1 |
actinin, alpha 1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of ACTN1 protein |
CTD |
PMID:25933445 |
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NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251
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Actn4 |
actinin alpha 4 |
decreases expression |
EXP |
Bleomycin results in decreased expression of ACTN4 protein |
CTD |
PMID:25933445 |
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NCBI chr 1:84,182,783...84,251,867
Ensembl chr 1:84,182,788...84,251,847
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Actr10 |
actin related protein 10 |
increases expression |
ISO |
Bleomycin results in increased expression of ACTR10 mRNA |
CTD |
PMID:36087614 |
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NCBI chr 6:89,446,141...89,472,350
Ensembl chr 6:89,446,093...89,473,047
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Actr3b |
actin related protein 3B |
increases expression |
ISO |
Bleomycin results in increased expression of ACTR3B mRNA |
CTD |
PMID:36087614 |
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NCBI chr 4:9,261,631...9,355,496
Ensembl chr 4:9,262,233...9,355,441
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Adam17 |
ADAM metallopeptidase domain 17 |
multiple interactions |
ISO |
Bleomycin results in increased expression of and results in increased activity of ADAM17 protein |
CTD |
PMID:22687607 |
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NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
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Adra1b |
adrenoceptor alpha 1B |
decreases expression |
EXP |
Bleomycin results in decreased expression of ADRA1B mRNA |
CTD |
PMID:15808516 |
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NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919
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Ager |
advanced glycosylation end product-specific receptor |
multiple interactions decreases expression |
EXP |
protocatechualdehyde inhibits the reaction [Bleomycin results in decreased expression of AGER protein] |
CTD |
PMID:25582705 PMID:25933445 |
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NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
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Agtr1a |
angiotensin II receptor, type 1a |
multiple interactions increases expression |
EXP |
angiotensin I (1-7) inhibits the reaction [Bleomycin results in increased expression of AGTR1 protein] |
CTD |
PMID:20581171 |
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NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
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Ahsg |
alpha-2-HS-glycoprotein |
increases expression |
EXP |
Bleomycin results in increased expression of AHSG protein |
CTD |
PMID:25933445 |
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NCBI chr11:78,121,388...78,127,998
Ensembl chr11:78,117,918...78,145,999
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Aifm1 |
apoptosis inducing factor, mitochondria associated 1 |
multiple interactions |
ISO |
5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin affects the expression of and affects the localization of AIFM1 protein]]; 5-hydroxydecanoic acid inhibits the reaction [Diazoxide inhibits the reaction [Bleomycin affects the expression of and affects the localization of AIFM1 protein]]; baicalein inhibits the reaction [Bleomycin affects the expression of and affects the localization of AIFM1 protein]; Bleomycin affects the expression of and affects the localization of AIFM1 protein; Diazoxide inhibits the reaction [Bleomycin affects the expression of and affects the localization of AIFM1 protein] |
CTD |
PMID:37783230 |
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NCBI chr X:127,650,223...127,689,356
Ensembl chr X:127,650,226...127,689,256
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Akt1 |
AKT serine/threonine kinase 1 |
increases phosphorylation |
ISO |
Bleomycin results in increased phosphorylation of AKT1 protein |
CTD |
PMID:22687607 PMID:26520185 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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Alb |
albumin |
increases expression |
EXP |
Bleomycin results in increased expression of ALB protein |
CTD |
PMID:25933445 |
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NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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Aldh1a1 |
aldehyde dehydrogenase 1 family, member A1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of ALDH1A1 protein |
CTD |
PMID:25933445 |
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NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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Aldoc |
aldolase, fructose-bisphosphate C |
multiple interactions |
ISO |
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ALDOC protein |
CTD |
PMID:29733421 |
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NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066
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Angptl3 |
angiopoietin-like 3 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of ANGPTL3 protein Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of ANGPTL3 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of ANGPTL3 protein] |
CTD |
PMID:30825431 |
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NCBI chr 5:113,703,007...113,710,044
Ensembl chr 5:113,703,012...113,709,957
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Ankrd1 |
ankyrin repeat domain 1 |
increases expression |
ISO |
Bleomycin results in increased expression of ANKRD1 mRNA |
CTD |
PMID:26345256 |
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NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919
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Anp32e |
acidic nuclear phosphoprotein 32 family member E |
increases expression |
EXP |
Bleomycin results in increased expression of ANP32E protein |
CTD |
PMID:25933445 |
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NCBI chr 2:183,472,600...183,489,057
Ensembl chr 2:183,472,609...183,489,054
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Anxa2 |
annexin A2 |
decreases expression |
EXP |
Bleomycin results in decreased expression of ANXA2 protein |
CTD |
PMID:25933445 |
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NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
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Anxa3 |
annexin A3 |
decreases expression |
EXP |
Bleomycin results in decreased expression of ANXA3 protein |
CTD |
PMID:25933445 |
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NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
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Anxa4 |
annexin A4 |
decreases expression |
EXP |
Bleomycin results in decreased expression of ANXA4 protein |
CTD |
PMID:25933445 |
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NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161
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Anxa5 |
annexin A5 |
increases expression |
EXP |
Bleomycin results in increased expression of ANXA5 protein |
CTD |
PMID:25933445 |
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NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
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Anxa6 |
annexin A6 |
decreases expression |
EXP |
Bleomycin results in decreased expression of ANXA6 protein |
CTD |
PMID:25933445 |
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NCBI chr10:39,101,395...39,156,483
Ensembl chr10:39,097,109...39,156,433
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Anxa7 |
annexin A7 |
multiple interactions |
ISO |
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ANXA7 protein |
CTD |
PMID:29733421 |
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NCBI chr15:3,821,798...3,849,659
Ensembl chr15:3,821,845...3,849,385
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Aqp1 |
aquaporin 1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of AQP1 mRNA |
CTD |
PMID:15782499 |
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NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690
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Areg |
amphiregulin |
increases expression |
ISO |
Bleomycin results in increased expression of AREG mRNA |
CTD |
PMID:26817844 |
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NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
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Arg1 |
arginase 1 |
increases expression multiple interactions decreases expression |
ISO |
Bleomycin results in increased expression of ARG1 mRNA; Bleomycin results in increased expression of ARG1 protein Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of ARG1 protein] |
CTD |
PMID:26345256 PMID:26526764 PMID:30825431 PMID:33647319 |
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NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
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Atf4 |
activating transcription factor 4 |
multiple interactions increases expression |
EXP |
pachymic acid inhibits the reaction [Bleomycin results in increased expression of ATF4 protein] |
CTD |
PMID:37163307 |
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NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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Atm |
ATM serine/threonine kinase |
multiple interactions increases phosphorylation |
ISO |
2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin promotes the reaction [resveratrol results in increased phosphorylation of ATM protein]]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin results in increased phosphorylation of ATM protein]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of ATM protein]]; Bleomycin promotes the reaction [resveratrol results in increased phosphorylation of ATM protein]; resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of ATM protein] |
CTD |
PMID:24933654 |
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NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
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Atp5f1b |
ATP synthase F1 subunit beta |
decreases expression |
EXP |
Bleomycin results in decreased expression of ATP5F1B protein |
CTD |
PMID:25933445 |
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NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273
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Atp5if1 |
ATP synthase inhibitory factor subunit 1 |
increases expression |
EXP |
Bleomycin results in increased expression of ATP5IF1 protein |
CTD |
PMID:25933445 |
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NCBI chr 5:144,738,950...144,742,668
Ensembl chr 5:144,738,950...144,742,668
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Atp5me |
ATP synthase membrane subunit e |
multiple interactions |
ISO |
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in increased expression of ATP5ME protein |
CTD |
PMID:29733421 |
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NCBI chr14:1,319,868...1,320,996
Ensembl chr14:1,319,868...1,321,013
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Atp5po |
ATP synthase peripheral stalk subunit OSCP |
decreases expression |
ISO |
Bleomycin results in decreased expression of ATP5PO protein |
CTD |
PMID:29733421 |
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NCBI chr11:31,165,218...31,171,530
Ensembl chr11:31,165,217...31,171,592
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Atp6v1a |
ATPase H+ transporting V1 subunit A |
multiple interactions decreases expression |
ISO |
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ATP6V1A protein Bleomycin results in decreased expression of ATP6V1A protein |
CTD |
PMID:29733421 |
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NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694
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Avpr1a |
arginine vasopressin receptor 1A |
decreases expression |
EXP |
Bleomycin results in decreased expression of AVPR1A mRNA |
CTD |
PMID:15808516 |
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NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215
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Basp1 |
brain abundant, membrane attached signal protein 1 |
increases expression |
EXP |
Bleomycin results in increased expression of BASP1 protein |
CTD |
PMID:25933445 |
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NCBI chr 2:75,816,130...75,863,801
Ensembl chr 2:75,816,122...75,864,043
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Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions increases expression |
EXP ISO |
allyl sulfide inhibits the reaction [Bleomycin results in increased expression of BAX protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of BAX mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of BAX mRNA] 5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin results in increased expression of BAX protein]]; 5-hydroxydecanoic acid inhibits the reaction [Diazoxide inhibits the reaction [Bleomycin results in increased expression of BAX protein]]; baicalein inhibits the reaction [Bleomycin results in increased expression of BAX protein]; Bleomycin inhibits the reaction [Azacitidine results in increased expression of BAX mRNA]; Diazoxide inhibits the reaction [Bleomycin results in increased expression of BAX protein] Bleomycin results in increased expression of BAX mRNA; Bleomycin results in increased expression of BAX protein |
CTD |
PMID:23656969 PMID:26093215 PMID:32278510 PMID:37783230 |
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bcl2 |
BCL2, apoptosis regulator |
multiple interactions decreases expression increases expression |
EXP ISO |
[Bleomycin co-treated with Bee Venoms] results in decreased expression of BCL2 mRNA; allyl sulfide promotes the reaction [Bleomycin results in increased expression of BCL2 protein]; Phytochemicals inhibits the reaction [Bleomycin results in decreased expression of BCL2 mRNA] Bleomycin results in decreased expression of BCL2 protein 5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin results in decreased expression of BCL2 protein]]; 5-hydroxydecanoic acid inhibits the reaction [Diazoxide inhibits the reaction [Bleomycin results in decreased expression of BCL2 protein]]; baicalein inhibits the reaction [Bleomycin results in decreased expression of BCL2 protein]; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of BCL2 mRNA]; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of BCL2 protein]; Diazoxide inhibits the reaction [Bleomycin results in decreased expression of BCL2 protein] [Polyphenols co-treated with Bleomycin] results in increased expression of BCL2 mRNA; [Tea co-treated with Bleomycin] results in increased expression of BCL2 mRNA |
CTD |
PMID:23656969 PMID:24822179 PMID:26093215 PMID:26800624 PMID:32278510 PMID:37783230 More...
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Bcl2l1 |
Bcl2-like 1 |
multiple interactions decreases expression |
ISO |
thymoquinone inhibits the reaction [Bleomycin results in decreased expression of BCL2L1 mRNA] |
CTD |
PMID:34818114 |
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NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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Bcl6b |
BCL6B, transcription repressor |
multiple interactions |
ISO |
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of BCL6B mRNA |
CTD |
PMID:29733421 |
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NCBI chr10:54,940,908...54,947,022
Ensembl chr10:54,940,909...54,945,974
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Bik |
BCL2-interacting killer |
increases expression |
ISO |
Bleomycin results in increased expression of BIK mRNA |
CTD |
PMID:36087614 |
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NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296
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Birc2 |
baculoviral IAP repeat-containing 2 |
decreases response to substance increases expression |
ISO EXP |
BIRC2 protein results in decreased susceptibility to Bleomycin Bleomycin results in increased expression of BIRC2 protein |
CTD |
PMID:10815900 PMID:15371238 |
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NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
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Birc5 |
baculoviral IAP repeat-containing 5 |
increases expression |
ISO |
Bleomycin results in increased expression of BIRC5 mRNA |
CTD |
PMID:26345256 |
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NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
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Blmh |
bleomycin hydrolase |
affects response to substance |
ISO |
BLMH gene polymorphism affects the susceptibility to Bleomycin |
CTD |
PMID:12082022 |
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NCBI chr10:61,772,112...61,815,212
Ensembl chr10:61,758,478...61,815,212
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Bmp7 |
bone morphogenetic protein 7 |
decreases expression |
ISO |
Bleomycin results in decreased expression of BMP7 mRNA |
CTD |
PMID:29408570 |
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NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
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Bscl2 |
BSCL2 lipid droplet biogenesis associated, seipin |
increases expression |
ISO |
Bleomycin results in increased expression of BSCL2 mRNA |
CTD |
PMID:22003191 |
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NCBI chr 1:205,731,828...205,743,430
Ensembl chr 1:205,733,872...205,743,421
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C1qb |
complement C1q B chain |
increases expression |
ISO |
Bleomycin results in increased expression of C1QB mRNA |
CTD |
PMID:26345256 |
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NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407
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Calca |
calcitonin-related polypeptide alpha |
increases expression |
ISO |
Bleomycin results in increased expression of CALCA mRNA |
CTD |
PMID:36087614 |
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NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
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Cald1 |
caldesmon 1 |
increases expression |
EXP |
Bleomycin results in increased expression of CALD1 protein |
CTD |
PMID:25933445 |
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NCBI chr 4:63,265,781...63,446,938
Ensembl chr 4:63,265,942...63,446,932
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Calml3 |
calmodulin-like 3 |
decreases expression |
EXP |
Bleomycin results in decreased expression of CALML3 protein |
CTD |
PMID:25933445 |
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NCBI chr17:66,419,844...66,423,083
Ensembl chr17:66,419,882...66,423,175
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G |
Calr |
calreticulin |
increases expression |
EXP |
Bleomycin results in increased expression of CALR protein |
CTD |
PMID:25933445 |
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NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
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G |
Calu |
calumenin |
increases expression |
EXP |
Bleomycin results in increased expression of CALU protein |
CTD |
PMID:25933445 |
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NCBI chr 4:57,949,086...57,976,589
Ensembl chr 4:57,948,997...57,976,593
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G |
Car1 |
carbonic anhydrase 1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of CA1 protein |
CTD |
PMID:25933445 |
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NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208
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G |
Car2 |
carbonic anhydrase 2 |
decreases expression |
EXP |
Bleomycin results in decreased expression of CA2 protein |
CTD |
PMID:25933445 |
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NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
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G |
Carhsp1 |
calcium regulated heat stable protein 1 |
increases expression |
EXP |
Bleomycin results in increased expression of CARHSP1 protein |
CTD |
PMID:25933445 |
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NCBI chr10:6,946,036...6,960,556
Ensembl chr10:6,946,959...7,020,019
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G |
Casp3 |
caspase 3 |
multiple interactions increases cleavage increases expression increases activity |
EXP ISO |
[Bleomycin co-treated with Bee Venoms] results in increased expression of CASP3 mRNA; allyl sulfide inhibits the reaction [Bleomycin results in increased expression of CASP3 protein]; Bleomycin results in increased cleavage of and results in increased activity of CASP3 protein; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of CASP3 mRNA] Bleomycin results in increased cleavage of CASP3 protein 5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin results in increased cleavage of CASP3 protein]]; baicalein inhibits the reaction [Bleomycin results in increased cleavage of CASP3 protein] [Polyphenols co-treated with Bleomycin] results in increased expression of CASP3 mRNA; [Tea co-treated with Bleomycin] results in increased expression of CASP3 mRNA Bleomycin results in increased expression of CASP3 mRNA; Bleomycin results in increased expression of CASP3 protein Bleomycin results in increased activity of CASP3 protein |
CTD |
PMID:15371238 PMID:22687607 PMID:23656969 PMID:24822179 PMID:26093215 PMID:26800624 PMID:37783230 More...
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp8 |
caspase 8 |
multiple interactions |
ISO |
[Polyphenols co-treated with Bleomycin] results in increased expression of CASP8 mRNA; [Tea co-treated with Bleomycin] results in increased expression of CASP8 mRNA |
CTD |
PMID:26800624 |
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NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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G |
Casp9 |
caspase 9 |
multiple interactions increases expression increases activity |
EXP ISO |
Bleomycin results in increased cleavage of and results in increased activity of CASP9 protein; pachymic acid inhibits the reaction [Bleomycin results in increased expression of CASP9 protein] [Polyphenols co-treated with Bleomycin] results in increased expression of CASP9 mRNA; [Tea co-treated with Bleomycin] results in increased expression of CASP9 mRNA Bleomycin results in increased activity of CASP9 protein |
CTD |
PMID:15371238 PMID:22687607 PMID:26800624 PMID:37163307 |
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Cast |
calpastatin |
increases expression |
EXP |
Bleomycin results in increased expression of CAST protein |
CTD |
PMID:25933445 |
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NCBI chr 2:3,973,112...4,082,658
Ensembl chr 2:3,973,112...4,082,659
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G |
Cat |
catalase |
increases response to substance decreases activity multiple interactions increases expression |
ISO EXP |
CAT protein results in increased susceptibility to Bleomycin Bleomycin results in decreased activity of CAT celastrol inhibits the reaction [Bleomycin results in decreased activity of CAT protein]; pachymic acid inhibits the reaction [Bleomycin results in decreased activity of CAT protein] IL1A protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of CAT protein] Bleomycin results in decreased expression of and results in decreased activity of CAT protein; caffeic acid phenethyl ester inhibits the reaction [Bleomycin results in decreased expression of CAT protein]; Oils, Volatile inhibits the reaction [Bleomycin results in decreased activity of CAT protein] |
CTD |
PMID:8317554 PMID:10751631 PMID:23570914 PMID:26768587 PMID:28850077 PMID:30106319 PMID:37163307 More...
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Cav1 |
caveolin 1 |
decreases expression multiple interactions |
EXP ISO |
Bleomycin results in decreased expression of CAV1 protein yupingfeng inhibits the reaction [Bleomycin results in decreased expression of CAV1 mRNA]; yupingfeng inhibits the reaction [Bleomycin results in decreased expression of CAV1 protein] Bleomycin results in decreased expression of CAV1 mRNA; Bleomycin results in decreased expression of CAV1 protein |
CTD |
PMID:25933445 PMID:37898439 |
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NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
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G |
Cavin2 |
caveolae associated protein 2 |
decreases expression |
EXP |
Bleomycin results in decreased expression of CAVIN2 protein |
CTD |
PMID:25933445 |
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NCBI chr 9:50,302,079...50,314,096
Ensembl chr 9:50,301,206...50,314,147
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G |
Cbx8 |
chromobox 8 |
decreases expression multiple interactions |
ISO |
Bleomycin results in decreased expression of CBX8 mRNA Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of CBX8 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of CBX8 mRNA] |
CTD |
PMID:30825431 |
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NCBI chr10:104,294,518...104,296,956
Ensembl chr10:104,294,518...104,297,024
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G |
Cckar |
cholecystokinin A receptor |
decreases expression |
EXP |
Bleomycin results in decreased expression of CCKAR mRNA |
CTD |
PMID:15808516 |
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NCBI chr14:57,292,397...57,300,747
Ensembl chr14:57,292,397...57,300,747
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G |
Ccl11 |
C-C motif chemokine ligand 11 |
increases expression decreases expression multiple interactions decreases response to substance |
ISO |
Bleomycin results in increased expression of CCL11 mRNA; Bleomycin results in increased expression of CCL11 protein Bleomycin results in decreased expression of CCL11 mRNA CCL11 protein promotes the reaction [Bleomycin results in increased expression of CCL2 mRNA]; CCL11 protein promotes the reaction [Bleomycin results in increased expression of TGFB1 mRNA] CCL11 gene mutant form results in decreased susceptibility to Bleomycin |
CTD |
PMID:16314464 PMID:29720568 |
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NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
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G |
Ccl12 |
C-C motif chemokine ligand 12 |
increases expression decreases expression multiple interactions |
ISO |
Bleomycin results in increased expression of CCL12 mRNA Bleomycin results in decreased expression of CCL12 mRNA [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; CCL12 protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]]; Dinoprostone inhibits the reaction [Bleomycin results in increased expression of CCL12 mRNA] |
CTD |
PMID:28434932 PMID:29720568 |
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NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780
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G |
Ccl17 |
C-C motif chemokine ligand 17 |
increases expression |
ISO |
Bleomycin results in increased expression of CCL17 mRNA; Bleomycin results in increased expression of CCL17 protein |
CTD |
PMID:26345256 PMID:29175452 |
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NCBI chr19:10,202,128...10,203,903
Ensembl chr19:10,202,128...10,203,819
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
increases expression multiple interactions decreases expression |
ISO EXP |
Bleomycin results in increased expression of CCL2 mRNA; Bleomycin results in increased expression of CCL2 protein [Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of CCL2 protein Bleomycin results in decreased expression of CCL2 mRNA Calcitriol inhibits the reaction [Bleomycin results in increased expression of CCL2 mRNA]; Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of CCL2 mRNA]; CCL11 protein promotes the reaction [Bleomycin results in increased expression of CCL2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of CCL2 mRNA]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Bleomycin results in increased expression of CCL2 mRNA]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of CCL2 protein]; SPL-334 inhibits the reaction [Bleomycin results in increased expression of CCL2 protein]; tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of CCL2 mRNA]; tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of CCL2 protein] |
CTD |
PMID:15541506 PMID:16314464 PMID:17177178 PMID:19147827 PMID:26209236 PMID:26520185 PMID:26526764 PMID:29720568 PMID:30033591 PMID:32828905 PMID:33516805 PMID:35112775 More...
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccl3 |
C-C motif chemokine ligand 3 |
increases expression decreases expression multiple interactions |
ISO EXP |
Bleomycin results in increased expression of CCL3 mRNA Bleomycin results in decreased expression of CCL3 protein [Bleomycin co-treated with Tobacco Smoke Pollution] affects the expression of CCL3 protein Bleomycin results in decreased expression of CCL3 mRNA Calcitriol inhibits the reaction [Bleomycin results in increased expression of CCL3 mRNA] |
CTD |
PMID:26520185 PMID:29720568 PMID:32828905 PMID:33516805 |
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NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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G |
Ccl4 |
C-C motif chemokine ligand 4 |
decreases expression |
ISO |
Bleomycin results in decreased expression of CCL4 mRNA |
CTD |
PMID:29720568 |
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NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of CCL5 mRNA SLCO2A1 gene mutant form promotes the reaction [Bleomycin results in increased expression of CCL5 mRNA] |
CTD |
PMID:32828905 |
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NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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G |
Ccl7 |
C-C motif chemokine ligand 7 |
decreases expression |
ISO |
Bleomycin results in decreased expression of CCL7 mRNA |
CTD |
PMID:29720568 |
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NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
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G |
Ccl9 |
C-C motif chemokine ligand 9 |
increases expression |
ISO |
Bleomycin results in increased expression of CCL6 protein |
CTD |
PMID:29175452 |
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NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369
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G |
Ccn2 |
cellular communication network factor 2 |
multiple interactions increases expression |
ISO |
[CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; honokiol inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]; OGG1 protein affects the reaction [Bleomycin results in increased expression of CCN2 protein]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]]; OGG1 protein promotes the reaction [Bleomycin results in increased expression of CCN2 protein]; pirfenidone inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of CCN2 mRNA]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]; TH5487 inhibits the reaction [Bleomycin results in increased expression of CCN2 protein] Bleomycin results in increased expression of CCN2 mRNA; Bleomycin results in increased expression of CCN2 protein |
CTD |
PMID:19080365 PMID:26817844 PMID:27153807 PMID:28434932 PMID:32032644 PMID:35654123 More...
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NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
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G |
Ccng1 |
cyclin G1 |
increases expression |
ISO |
Bleomycin results in increased expression of CCNG1 mRNA |
CTD |
PMID:26345256 |
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NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
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G |
Ccr2 |
C-C motif chemokine receptor 2 |
multiple interactions increases expression decreases response to substance |
ISO |
CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of TNF mRNA] Bleomycin results in increased expression of CCR2 mRNA CCR2 gene mutant form results in decreased susceptibility to Bleomycin |
CTD |
PMID:14609568 PMID:29033951 |
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NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
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G |
Ccr3 |
C-C motif chemokine receptor 3 |
increases expression |
ISO |
Bleomycin results in increased expression of CCR3 mRNA; Bleomycin results in increased expression of CCR3 protein |
CTD |
PMID:16314464 |
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NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:123,616,236...123,634,990
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G |
Ccr5 |
C-C motif chemokine receptor 5 |
affects expression multiple interactions increases expression |
ISO |
Bleomycin affects the expression of CCR5 mRNA Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of CCR5 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of CCR5 mRNA] |
CTD |
PMID:26345256 PMID:30825431 |
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NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
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G |
Cct8 |
chaperonin containing TCP1 subunit 8 |
multiple interactions |
ISO |
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of CCT8 protein |
CTD |
PMID:29733421 |
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NCBI chr11:26,710,370...26,722,079
Ensembl chr11:26,710,370...26,722,079
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G |
Cd14 |
CD14 molecule |
increases expression |
ISO |
Bleomycin results in increased expression of CD14 mRNA |
CTD |
PMID:36087614 |
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NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
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G |
Cd2 |
Cd2 molecule |
increases expression |
ISO |
Bleomycin results in increased expression of CD2 mRNA |
CTD |
PMID:36087614 |
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NCBI chr 2:188,710,895...188,724,044
Ensembl chr 2:188,710,900...188,724,026
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G |
Cd33 |
CD33 molecule |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of CD33 mRNA Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of CD33 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of CD33 mRNA] |
CTD |
PMID:30825431 |
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NCBI chr 1:93,935,418...93,940,452
Ensembl chr 1:93,930,971...93,950,149
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G |
Cd34 |
CD34 molecule |
multiple interactions decreases expression |
ISO |
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of CD34 protein] |
CTD |
PMID:30825431 |
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NCBI chr13:106,480,313...106,500,844
Ensembl chr13:106,480,043...106,499,832
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G |
Cd36 |
CD36 molecule |
decreases expression |
ISO |
Bleomycin results in decreased expression of CD36 mRNA |
CTD |
PMID:29408570 |
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NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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G |
Cd44 |
CD44 molecule |
multiple interactions increases expression |
ISO |
honokiol inhibits the reaction [Bleomycin results in increased expression of CD44 protein] |
CTD |
PMID:32032644 |
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NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
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G |
Cd83 |
CD83 molecule |
increases expression |
ISO |
Bleomycin results in increased expression of CD83 mRNA |
CTD |
PMID:36087614 |
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NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083
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G |
Cd86 |
CD86 molecule |
decreases expression |
ISO |
Bleomycin results in decreased expression of CD86 mRNA |
CTD |
PMID:29720568 |
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NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
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G |
Cdc20 |
cell division cycle 20 |
increases expression |
ISO |
Bleomycin results in increased expression of CDC20 mRNA |
CTD |
PMID:26345256 |
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NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
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G |
Cdh1 |
cadherin 1 |
multiple interactions decreases expression |
ISO EXP |
12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; Dexamethasone inhibits the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; geranylgeranylacetone inhibits the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; geranylgeranylacetone inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; honokiol inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; MIR100HG mRNA affects the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; MIR100HG mRNA affects the reaction [Bleomycin results in decreased expression of CDH1 protein]; OGG1 protein affects the reaction [Bleomycin results in decreased expression of CDH1 protein]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]]; pirfenidone inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; TH5487 inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein] Ephedrine inhibits the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; Ephedrine inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein] Bleomycin results in decreased expression of CDH1 mRNA; Bleomycin results in decreased expression of CDH1 protein |
CTD |
PMID:28300665 PMID:28694203 PMID:32032644 PMID:34425168 PMID:35472619 PMID:35654123 PMID:37126650 PMID:37307957 PMID:37778983 More...
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NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
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G |
Cdh2 |
cadherin 2 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of CDH2 protein OGG1 protein affects the reaction [Bleomycin results in increased expression of CDH2 protein]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in increased expression of CDH2 protein]]; pirfenidone inhibits the reaction [Bleomycin results in increased expression of CDH2 protein]; TH5487 inhibits the reaction [Bleomycin results in increased expression of CDH2 protein] |
CTD |
PMID:35654123 |
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NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression |
ISO |
Bleomycin results in increased expression of CDKN1A mRNA |
CTD |
PMID:26345256 PMID:29720568 PMID:32554301 |
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NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cebpb |
CCAAT/enhancer binding protein beta |
increases expression increases response to substance multiple interactions decreases response to substance |
ISO |
Bleomycin results in increased expression of CEBPB mRNA CEBPB protein results in increased susceptibility to Bleomycin CEBPB protein affects the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of CCL2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of IL1B mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of TNF mRNA] CEBPB gene mutant form results in decreased susceptibility to Bleomycin |
CTD |
PMID:17177178 PMID:21998664 |
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NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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G |
Cemip2 |
cell migration inducing hyaluronidase 2 |
decreases expression |
ISO |
Bleomycin results in decreased expression of CEMIP2 mRNA |
CTD |
PMID:33770205 |
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NCBI chr 1:219,330,295...219,407,760
Ensembl chr 1:219,337,985...219,407,760
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G |
Cenpe |
centromere protein E |
multiple interactions decreases expression |
ISO |
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of CENPE mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of CENPE mRNA] |
CTD |
PMID:30825431 |
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NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669
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G |
Cert1 |
ceramide transporter 1 |
increases expression |
ISO |
Bleomycin results in increased expression of CERT1 mRNA |
CTD |
PMID:36087614 |
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NCBI chr 2:27,882,546...27,987,090
Ensembl chr 2:27,882,555...27,987,074
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G |
Ces1d |
carboxylesterase 1D |
decreases expression |
EXP |
Bleomycin results in decreased expression of CES1 protein |
CTD |
PMID:25933445 |
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NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
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G |
Cfl1 |
cofilin 1 |
increases expression |
EXP |
Bleomycin results in increased expression of CFL1 protein |
CTD |
PMID:25933445 |
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NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
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G |
Chek2 |
checkpoint kinase 2 |
increases phosphorylation multiple interactions |
ISO |
Bleomycin results in increased phosphorylation of CHEK2 protein resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of CHEK2 protein] |
CTD |
PMID:24933654 |
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NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
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G |
Chrnb2 |
cholinergic receptor nicotinic beta 2 subunit |
decreases expression |
EXP |
Bleomycin results in decreased expression of CHRNB2 mRNA |
CTD |
PMID:15808516 |
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NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
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G |
Ckb |
creatine kinase B |
increases expression |
EXP |
Bleomycin results in increased expression of CKB protein |
CTD |
PMID:25933445 |
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NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
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G |
Clcn5 |
chloride voltage-gated channel 5 |
increases expression |
EXP |
Bleomycin results in increased expression of CLCN5 mRNA |
CTD |
PMID:15808516 |
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NCBI chr X:15,185,380...15,339,977
Ensembl chr X:15,185,451...15,334,264
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G |
Cldn4 |
claudin 4 |
increases expression |
ISO |
Bleomycin results in increased expression of CLDN4 mRNA |
CTD |
PMID:26345256 |
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NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436
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Clic4 |
chloride intracellular channel 4 |
decreases expression |
EXP |
Bleomycin results in decreased expression of CLIC4 protein |
CTD |
PMID:25933445 |
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NCBI chr 5:147,453,702...147,513,455
Ensembl chr 5:147,453,712...147,513,452
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G |
Clic5 |
chloride intracellular channel 5 |
decreases expression |
EXP |
Bleomycin results in decreased expression of CLIC5 protein |
CTD |
PMID:25933445 |
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NCBI chr 9:16,710,980...16,813,502
Ensembl chr 9:16,710,980...16,813,427
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G |
Cltc |
clathrin heavy chain |
decreases expression |
EXP |
Bleomycin results in decreased expression of CLTC protein |
CTD |
PMID:25933445 |
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NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737
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G |
Cnr1 |
cannabinoid receptor 1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of CNR1 mRNA |
CTD |
PMID:15808516 |
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NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
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G |
Col11a2 |
collagen type XI alpha 2 chain |
increases expression |
ISO |
Bleomycin results in increased expression of COL11A2 mRNA |
CTD |
PMID:36087614 |
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NCBI chr20:4,786,932...4,816,598
Ensembl chr20:4,786,929...4,815,985
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G |
Col14a1 |
collagen type XIV alpha 1 chain |
increases expression |
ISO |
Bleomycin results in increased expression of COL14A1 mRNA |
CTD |
PMID:36087614 |
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NCBI chr 7:86,722,093...86,937,215
Ensembl chr 7:86,722,094...86,937,214
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G |
Col18a1 |
collagen type XVIII alpha 1 chain |
increases expression |
ISO |
Bleomycin results in increased expression of COL18A1 mRNA |
CTD |
PMID:36087614 |
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NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593
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G |
Col1a1 |
collagen type I alpha 1 chain |
multiple interactions increases expression decreases expression |
ISO EXP |
5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]]; 5-hydroxydecanoic acid inhibits the reaction [Diazoxide inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]]; [Bleomycin co-treated with Soot] results in increased expression of COL1A1 protein; Arsenic Trioxide inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Arsenic Trioxide inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; baicalein inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Diazoxide inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Enalapril inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; icaritin inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; S1PR5 protein affects the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Thioctic Acid inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA] MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA] Bleomycin results in increased expression of COL1A1 mRNA; Bleomycin results in increased expression of COL1A1 protein Bleomycin results in decreased expression of COL1A1 protein Curcumin inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA] |
CTD |
PMID:12003776 PMID:14609568 PMID:17434272 PMID:19147827 PMID:24762191 PMID:25933445 PMID:26093215 PMID:26345256 PMID:28300665 PMID:28726637 PMID:29033951 PMID:31302203 PMID:34153405 PMID:34425168 PMID:35187969 PMID:37307957 PMID:37399107 PMID:37783230 More...
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NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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G |
Col1a2 |
collagen type I alpha 2 chain |
increases expression multiple interactions decreases expression |
ISO EXP |
Bleomycin results in increased expression of COL1A2 mRNA; Bleomycin results in increased expression of COL1A2 protein pachymic acid inhibits the reaction [Bleomycin results in increased expression of COL1A2 protein] Bleomycin results in decreased expression of COL1A2 protein geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of COL1A2 mRNA]; geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of COL1A2 protein]; MIR100HG mRNA affects the reaction [Bleomycin results in increased expression of COL1A2 protein]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of COL1A2 mRNA] |
CTD |
PMID:19147827 PMID:25933445 PMID:35472619 PMID:37163307 PMID:37307957 |
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NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
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G |
Col22a1 |
collagen type XXII alpha 1 chain |
increases expression |
ISO |
Bleomycin results in increased expression of COL22A1 mRNA |
CTD |
PMID:36087614 |
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NCBI chr 7:103,730,939...103,968,452
Ensembl chr 7:103,731,037...103,968,462
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G |
Col24a1 |
collagen type XXIV alpha 1 chain |
increases expression |
ISO |
Bleomycin results in increased expression of COL24A1 mRNA |
CTD |
PMID:36087614 |
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NCBI chr 2:234,212,256...234,469,445
Ensembl chr 2:234,212,324...234,469,441
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G |
Col3a1 |
collagen type III alpha 1 chain |
decreases expression multiple interactions increases expression |
EXP ISO |
Bleomycin results in decreased expression of COL3A1 protein honokiol inhibits the reaction [Bleomycin results in increased expression of COL3A1 protein] MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL3A1 mRNA] Bleomycin results in increased expression of COL3A1 mRNA; Bleomycin results in increased expression of COL3A1 protein |
CTD |
PMID:25933445 PMID:26817844 PMID:28726637 PMID:32032644 |
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NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
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G |
Col4a4 |
collagen type IV alpha 4 chain |
increases expression |
ISO |
Bleomycin results in increased expression of COL4A4 mRNA |
CTD |
PMID:36087614 |
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NCBI chr 9:83,833,173...83,875,436
Ensembl chr 9:83,755,515...83,875,876
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G |
Col5a1 |
collagen type V alpha 1 chain |
decreases expression increases expression |
EXP ISO |
Bleomycin results in decreased expression of COL5A1 protein Bleomycin results in increased expression of COL5A1 mRNA |
CTD |
PMID:25933445 PMID:36087614 |
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NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588
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G |
Col5a2 |
collagen type V alpha 2 chain |
increases expression |
ISO |
Bleomycin results in increased expression of COL5A2 mRNA |
CTD |
PMID:36087614 |
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NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154
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G |
Col5a3 |
collagen type V alpha 3 chain |
increases expression |
ISO |
Bleomycin results in increased expression of COL5A3 mRNA |
CTD |
PMID:36087614 |
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NCBI chr 8:19,304,564...19,349,809
Ensembl chr 8:19,304,571...19,349,853
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G |
Col6a3 |
collagen type VI alpha 3 chain |
increases expression |
ISO |
Bleomycin results in increased expression of COL6A3 mRNA |
CTD |
PMID:36087614 |
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NCBI chr 9:91,361,578...91,439,434
Ensembl chr 9:91,361,583...91,439,471
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G |
Col9a2 |
collagen type IX alpha 2 chain |
increases expression |
ISO |
Bleomycin results in increased expression of COL9A2 mRNA |
CTD |
PMID:36087614 |
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NCBI chr 5:134,607,616...134,624,678
Ensembl chr 5:134,607,616...134,624,677
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G |
Colq |
collagen like tail subunit of asymmetric acetylcholinesterase |
increases expression |
ISO |
Bleomycin results in increased expression of COLQ mRNA |
CTD |
PMID:36087614 |
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NCBI chr16:6,731,850...6,824,973
Ensembl chr16:6,731,858...6,787,107
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G |
Comp |
cartilage oligomeric matrix protein |
multiple interactions |
ISO |
[S1PR5 protein affects the susceptibility to Bleomycin] which affects the expression of COMP protein |
CTD |
PMID:29033951 |
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NCBI chr16:19,047,206...19,055,584
Ensembl chr16:19,047,207...19,055,845
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G |
Cp |
ceruloplasmin |
multiple interactions increases expression |
ISO |
tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of CP protein] |
CTD |
PMID:12624602 |
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NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
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G |
Crip2 |
cysteine-rich protein 2 |
affects expression |
EXP |
Bleomycin affects the expression of CRIP2 protein |
CTD |
PMID:25933445 |
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NCBI chr 6:132,221,120...132,226,066
Ensembl chr 6:132,221,082...132,226,065
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G |
Csf2 |
colony stimulating factor 2 |
increases expression multiple interactions decreases expression |
ISO |
Bleomycin results in increased expression of CSF2 mRNA; Bleomycin results in increased expression of CSF2 protein 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Bleomycin results in increased expression of CSF2 mRNA]; Apigenin inhibits the reaction [Bleomycin results in increased expression of CSF2 mRNA] Bleomycin results in decreased expression of CSF2 mRNA |
CTD |
PMID:18684396 PMID:29720568 PMID:32554301 |
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NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
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G |
Csf2rb |
colony stimulating factor 2 receptor subunit beta |
increases expression |
ISO |
Bleomycin results in increased expression of CSF2RB2 mRNA |
CTD |
PMID:36087614 |
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NCBI chr 7:109,876,919...109,901,589
Ensembl chr 7:109,886,425...109,904,157
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G |
Csf3 |
colony stimulating factor 3 |
decreases expression |
EXP |
Bleomycin results in decreased expression of CSF3 mRNA |
CTD |
PMID:15808516 |
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NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
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G |
Csrp1 |
cysteine and glycine-rich protein 1 |
increases expression |
EXP |
Bleomycin results in increased expression of CSRP1 protein |
CTD |
PMID:25933445 |
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NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384
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G |
Ctsa |
cathepsin A |
affects expression |
ISO |
Bleomycin affects the expression of CTSA mRNA |
CTD |
PMID:26345256 |
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NCBI chr 3:153,569,106...153,574,983
Ensembl chr 3:153,568,381...153,576,215
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G |
Ctsb |
cathepsin B |
affects expression |
ISO |
Bleomycin affects the expression of CTSB mRNA |
CTD |
PMID:26345256 |
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NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
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G |
Ctsh |
cathepsin H |
affects expression |
ISO |
Bleomycin affects the expression of CTSH mRNA |
CTD |
PMID:26345256 |
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NCBI chr 8:90,608,941...90,627,824
Ensembl chr 8:90,608,941...90,627,824
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G |
Ctss |
cathepsin S |
increases expression |
ISO |
Bleomycin results in increased expression of CTSS mRNA |
CTD |
PMID:19101991 |
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NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483
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G |
Cx3cl1 |
C-X3-C motif chemokine ligand 1 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of CX3CL1 protein Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of CX3CL1 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of CX3CL1 protein] |
CTD |
PMID:30825431 |
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NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
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G |
Cxcl1 |
C-X-C motif chemokine ligand 1 |
multiple interactions increases expression |
ISO |
5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Bleomycin results in increased expression of CXCL1 mRNA]; Apigenin inhibits the reaction [Bleomycin results in increased expression of CXCL1 mRNA] |
CTD |
PMID:32554301 |
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NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
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G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
increases expression multiple interactions decreases expression |
ISO EXP |
Bleomycin results in increased expression of CXCL10 mRNA; Bleomycin results in increased expression of CXCL10 protein [Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of CXCL10 protein Bleomycin results in decreased expression of CXCL10 mRNA |
CTD |
PMID:26345256 PMID:29720568 PMID:33516805 PMID:36087614 |
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NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
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G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
increases expression |
ISO |
Bleomycin results in increased expression of CXCL12 mRNA |
CTD |
PMID:29720568 |
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NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
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G |
Cxcl13 |
C-X-C motif chemokine ligand 13 |
affects expression |
ISO |
Bleomycin affects the expression of CXCL13 mRNA |
CTD |
PMID:26345256 |
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NCBI chr14:13,608,894...13,613,965
Ensembl chr14:13,608,902...13,613,933
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G |
Cxcl14 |
C-X-C motif chemokine ligand 14 |
increases expression |
ISO |
Bleomycin results in increased expression of CXCL14 mRNA |
CTD |
PMID:36087614 |
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NCBI chr17:8,317,930...8,325,956
Ensembl chr17:8,317,933...8,324,839
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
increases expression multiple interactions increases secretion |
ISO EXP |
Bleomycin results in increased expression of CXCL2 protein [Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of CXCL2 protein 3-aminobenzamide inhibits the reaction [Bleomycin results in increased secretion of CXCL2 protein]; Calcitriol inhibits the reaction [Bleomycin results in increased expression of CXCL2 mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Bleomycin results in increased secretion of CXCL2 protein]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of CXCL2 protein] |
CTD |
PMID:18684396 PMID:22687607 PMID:26520185 PMID:26600069 PMID:33516805 |
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NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
multiple interactions increases expression increases secretion |
ISO |
TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of CXCL1 protein] Bleomycin results in increased expression of CXCL1 mRNA 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Bleomycin results in increased expression of CXCL1 mRNA]; Apigenin inhibits the reaction [Bleomycin results in increased expression of CXCL1 mRNA] Bleomycin results in increased expression of CXCL1 protein |
CTD |
PMID:26600069 PMID:32554301 PMID:36087614 |
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NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
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G |
Cxcl9 |
C-X-C motif chemokine ligand 9 |
increases expression |
ISO |
Bleomycin results in increased expression of CXCL9 protein |
CTD |
PMID:29175452 |
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NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
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G |
Cxcr1 |
C-X-C motif chemokine receptor 1 |
increases expression |
ISO |
Bleomycin results in increased expression of CXCR1 mRNA |
CTD |
PMID:36087614 |
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NCBI chr 9:75,766,894...75,771,079
Ensembl chr 9:75,766,770...75,771,084
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G |
Cyba |
cytochrome b-245 alpha chain |
multiple interactions increases expression |
ISO |
Thioctic Acid inhibits the reaction [Bleomycin results in increased expression of CYBA mRNA] |
CTD |
PMID:35187969 |
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NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
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G |
Cycs |
cytochrome c, somatic |
affects localization |
EXP |
Bleomycin affects the localization of CYCS protein |
CTD |
PMID:15371238 |
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NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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G |
Dbi |
diazepam binding inhibitor |
increases expression |
EXP |
Bleomycin results in increased expression of DBI protein |
CTD |
PMID:25933445 |
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NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression multiple interactions |
EXP |
Bleomycin results in increased expression of DDIT3 protein pachymic acid inhibits the reaction [Bleomycin results in increased expression of DDIT3 protein] |
CTD |
PMID:37163307 |
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NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Des |
desmin |
increases expression |
EXP |
Bleomycin results in increased expression of DES protein |
CTD |
PMID:25933445 |
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NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699
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G |
Dlat |
dihydrolipoamide S-acetyltransferase |
decreases expression |
ISO |
Bleomycin results in decreased expression of DLAT protein |
CTD |
PMID:29733421 |
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NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479
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G |
Dld |
dihydrolipoamide dehydrogenase |
increases expression |
EXP ISO |
Bleomycin results in increased expression of DLD protein |
CTD |
PMID:25933445 PMID:29733421 |
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NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795
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G |
Dlk1 |
delta like non-canonical Notch ligand 1 |
increases expression |
ISO |
Bleomycin results in increased expression of DLK1 protein |
CTD |
PMID:29175452 |
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NCBI chr 6:128,410,216...128,417,518
Ensembl chr 6:128,410,316...128,417,522
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G |
Dll4 |
delta like canonical Notch ligand 4 |
multiple interactions decreases expression |
ISO |
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of DLL4 protein]; lenabasum promotes the reaction [Bleomycin results in decreased expression of DLL4 protein] |
CTD |
PMID:30825431 |
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NCBI chr 3:106,317,114...106,327,004
Ensembl chr 3:106,316,986...106,326,931
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G |
Dnm1l |
dynamin 1-like |
increases expression |
ISO |
Bleomycin results in increased expression of DNM1L protein |
CTD |
PMID:37126650 |
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NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
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G |
Dnmt1 |
DNA methyltransferase 1 |
affects response to substance |
ISO |
DNMT1 protein affects the susceptibility to Bleomycin |
CTD |
PMID:17991895 |
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NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
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G |
Dpep1 |
dipeptidase 1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of DPEP1 protein |
CTD |
PMID:25933445 |
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NCBI chr19:51,209,831...51,237,004
Ensembl chr19:51,219,660...51,235,257
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G |
Ech1 |
enoyl-CoA hydratase 1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of ECH1 protein |
CTD |
PMID:25933445 |
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NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795
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G |
Edn1 |
endothelin 1 |
multiple interactions increases expression |
EXP |
Phytochemicals inhibits the reaction [Bleomycin results in increased expression of EDN1 mRNA] |
CTD |
PMID:26093215 |
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NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
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G |
Eef1a1 |
eukaryotic translation elongation factor 1 alpha 1 |
increases expression |
ISO |
Bleomycin results in increased expression of EEF1A1 protein |
CTD |
PMID:29733421 |
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NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839
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G |
Egr1 |
early growth response 1 |
increases expression affects expression multiple interactions |
ISO |
Bleomycin results in increased expression of EGR1 mRNA Bleomycin affects the expression of EGR1 mRNA rosiglitazone inhibits the reaction [Bleomycin results in increased expression of EGR1 mRNA] |
CTD |
PMID:19147827 PMID:26345256 |
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NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
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G |
Egr2 |
early growth response 2 |
affects expression |
ISO |
Bleomycin affects the expression of EGR2 mRNA |
CTD |
PMID:26345256 |
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NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
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G |
Ehd1 |
EH-domain containing 1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of EHD1 protein |
CTD |
PMID:25933445 |
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NCBI chr 1:203,579,850...203,602,226
Ensembl chr 1:203,579,869...203,602,212
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G |
Ehd2 |
EH-domain containing 2 |
decreases expression |
EXP |
Bleomycin results in decreased expression of EHD2 protein |
CTD |
PMID:25933445 |
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NCBI chr 1:76,639,568...76,658,747
Ensembl chr 1:76,637,482...76,658,783
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G |
Eif5a |
eukaryotic translation initiation factor 5A |
increases expression |
EXP |
Bleomycin results in increased expression of EIF5A protein |
CTD |
PMID:25933445 |
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NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656
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G |
Eln |
elastin |
increases expression |
ISO |
Bleomycin results in increased expression of ELN mRNA |
CTD |
PMID:26817844 |
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NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928
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G |
Emcn |
endomucin |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of EMCN mRNA Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of EMCN mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of EMCN mRNA] |
CTD |
PMID:30825431 |
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NCBI chr 2:225,891,100...225,970,932
Ensembl chr 2:225,891,100...225,970,929
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G |
Eng |
endoglin |
multiple interactions increases expression |
ISO |
Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of ENG protein] |
CTD |
PMID:30825431 |
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NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230
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G |
Epx |
eosinophil peroxidase |
increases expression |
EXP |
Bleomycin results in increased expression of EPX protein |
CTD |
PMID:26093215 |
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NCBI chr10:72,666,865...72,677,952
Ensembl chr10:72,666,865...72,677,952
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G |
Errfi1 |
ERBB receptor feedback inhibitor 1 |
decreases expression |
ISO |
Bleomycin results in decreased expression of ERRFI1 mRNA |
CTD |
PMID:33770205 |
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NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282
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G |
Espl1 |
extra spindle pole bodies like 1, separase |
multiple interactions decreases expression |
ISO |
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of ESPL1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of ESPL1 mRNA] |
CTD |
PMID:30825431 |
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NCBI chr 7:133,424,027...133,450,984
Ensembl chr 7:133,424,130...133,450,984
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G |
Ets1 |
ETS proto-oncogene 1, transcription factor |
decreases expression |
ISO |
Bleomycin results in decreased expression of ETS1 mRNA |
CTD |
PMID:28726637 |
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NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010
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G |
Ets2 |
ETS proto-oncogene 2, transcription factor |
decreases expression |
ISO |
Bleomycin results in decreased expression of ETS2 mRNA |
CTD |
PMID:28726637 |
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NCBI chr11:35,021,536...35,038,322
Ensembl chr11:35,021,596...35,038,319
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G |
Ezr |
ezrin |
decreases expression |
EXP |
Bleomycin results in decreased expression of EZR protein |
CTD |
PMID:25933445 |
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NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505
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G |
F2rl1 |
F2R like trypsin receptor 1 |
multiple interactions increases expression |
EXP |
allyl sulfide inhibits the reaction [Bleomycin results in increased expression of F2RL1 mRNA]; allyl sulfide inhibits the reaction [Bleomycin results in increased expression of F2RL1 protein] Bleomycin results in increased expression of F2RL1 mRNA; Bleomycin results in increased expression of F2RL1 protein |
CTD |
PMID:23656969 |
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NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226
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G |
Fabp4 |
fatty acid binding protein 4 |
decreases expression |
ISO |
Bleomycin results in decreased expression of FABP4 mRNA |
CTD |
PMID:29408570 |
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NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
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G |
Faslg |
Fas ligand |
increases expression |
ISO |
Bleomycin results in increased expression of FASLG mRNA |
CTD |
PMID:11350791 |
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NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
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G |
Fgf1 |
fibroblast growth factor 1 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of FGF1 protein Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of FGF1 protein] |
CTD |
PMID:30825431 |
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NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
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G |
Fgf2 |
fibroblast growth factor 2 |
increases expression multiple interactions |
EXP ISO |
Bleomycin results in increased expression of FGF2 protein Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of FGF2 protein] protocatechualdehyde inhibits the reaction [Bleomycin results in increased expression of FGF2 protein] |
CTD |
PMID:25582705 PMID:30825431 |
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NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
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G |
Fgf21 |
fibroblast growth factor 21 |
decreases expression multiple interactions |
ISO |
Bleomycin results in decreased expression of FGF21 protein Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of FGF21 protein] |
CTD |
PMID:30825431 |
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NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454
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G |
Fgf7 |
fibroblast growth factor 7 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of FGF7 protein Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of FGF7 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of FGF7 protein] |
CTD |
PMID:30825431 |
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NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929
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G |
Fhl1 |
four and a half LIM domains 1 |
increases expression |
EXP |
Bleomycin results in increased expression of FHL1 protein |
CTD |
PMID:25933445 |
|
NCBI chr X:134,555,399...134,614,930
Ensembl chr X:134,555,479...134,614,928
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G |
Fkbp10 |
FKBP prolyl isomerase 10 |
increases expression |
ISO |
Bleomycin results in increased expression of FKBP10 mRNA |
CTD |
PMID:36087614 |
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NCBI chr10:85,345,434...85,357,998
Ensembl chr10:85,346,126...85,427,330
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G |
Fn1 |
fibronectin 1 |
increases expression multiple interactions |
EXP ISO |
Bleomycin results in increased expression of FN1 protein pachymic acid inhibits the reaction [Bleomycin results in increased expression of FN1 protein] Bleomycin results in increased expression of FN1 mRNA Bleomycin results in increased expression of FN1 mRNA; Bleomycin results in increased expression of FN1 protein [Bleomycin co-treated with Soot] results in increased expression of FN1 protein; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of FN1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of FN1 mRNA]; geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of FN1 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; honokiol inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; OGG1 protein affects the reaction [Bleomycin results in increased expression of FN1 protein]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in increased expression of FN1 protein]]; OGG1 protein promotes the reaction [Bleomycin results in increased expression of FN1 protein]; pirfenidone inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; Soot promotes the reaction [Bleomycin results in increased expression of FN1 mRNA]; TH5487 inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; Thioctic Acid inhibits the reaction [Bleomycin results in increased expression of FN1 mRNA] |
CTD |
PMID:25071917 PMID:25933445 PMID:26345256 PMID:26817844 PMID:28300665 PMID:31302203 PMID:32032644 PMID:34460027 PMID:35187969 PMID:35267148 PMID:35654123 PMID:37163307 PMID:37307957 PMID:37399107 More...
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NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
increases activity multiple interactions |
ISO |
Bleomycin results in increased activity of FOS protein Bleomycin results in increased expression of [JUN protein binds to FOS protein] |
CTD |
PMID:12003776 PMID:37399107 |
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NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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G |
Foxp3 |
forkhead box P3 |
increases expression |
ISO |
Bleomycin results in increased expression of FOXP3 mRNA |
CTD |
PMID:29033951 |
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NCBI chr X:14,908,494...14,924,994
Ensembl chr X:14,908,494...14,923,838
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G |
Foxq1 |
forkhead box Q1 |
increases expression |
ISO |
Bleomycin results in increased expression of FOXQ1 mRNA |
CTD |
PMID:36087614 |
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NCBI chr17:32,912,744...32,915,377
Ensembl chr17:32,912,744...32,915,377 Ensembl chr17:32,912,744...32,915,377
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G |
Foxr1 |
forkhead box R1 |
increases expression |
ISO |
Bleomycin results in increased expression of FOXR1 mRNA |
CTD |
PMID:36087614 |
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NCBI chr 8:44,760,587...44,768,696
Ensembl chr 8:44,760,948...44,768,880
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G |
Fshb |
follicle stimulating hormone subunit beta |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of FSHB protein thymoquinone inhibits the reaction [Bleomycin results in increased expression of FSHB protein] |
CTD |
PMID:34818114 |
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NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
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G |
Fshr |
follicle stimulating hormone receptor |
decreases expression |
EXP |
Bleomycin results in decreased expression of FSHR mRNA |
CTD |
PMID:15808516 |
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NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785
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G |
Fubp1 |
far upstream element binding protein 1 |
increases expression |
EXP |
Bleomycin results in increased expression of FUBP1 protein |
CTD |
PMID:25933445 |
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NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602
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G |
Fzd6 |
frizzled class receptor 6 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of FZD6 mRNA MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of FZD6 mRNA] |
CTD |
PMID:28726637 |
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NCBI chr 7:70,055,012...70,086,781
Ensembl chr 7:70,055,068...70,086,776
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G |
Gabra4 |
gamma-aminobutyric acid type A receptor subunit alpha 4 |
decreases expression |
EXP |
Bleomycin results in decreased expression of GABRA4 mRNA |
CTD |
PMID:15808516 |
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NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844
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G |
Gabrb2 |
gamma-aminobutyric acid type A receptor subunit beta 2 |
decreases expression |
EXP |
Bleomycin results in decreased expression of GABRB2 mRNA |
CTD |
PMID:15808516 |
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NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251
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G |
Gabrg2 |
gamma-aminobutyric acid type A receptor subunit gamma 2 |
decreases expression |
EXP |
Bleomycin results in decreased expression of GABRG2 mRNA |
CTD |
PMID:15808516 |
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NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346
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G |
Gabrr1 |
gamma-aminobutyric acid type A receptor subunit rho 1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of GABRR1 mRNA |
CTD |
PMID:15808516 |
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NCBI chr 5:47,524,151...47,561,228
Ensembl chr 5:47,524,151...47,561,228
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G |
Ganab |
glucosidase II alpha subunit |
multiple interactions |
ISO |
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of GANAB protein |
CTD |
PMID:29733421 |
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NCBI chr 1:205,793,910...205,813,704
Ensembl chr 1:205,793,895...205,813,695
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G |
Gas6 |
growth arrest specific 6 |
increases expression |
ISO |
Bleomycin results in increased expression of GAS6 protein |
CTD |
PMID:29175452 |
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NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
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G |
Gata3 |
GATA binding protein 3 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of GATA3 mRNA S1PR5 protein affects the reaction [Bleomycin results in increased expression of GATA3 mRNA] |
CTD |
PMID:29033951 |
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NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
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G |
Gc |
GC, vitamin D binding protein |
increases expression |
EXP |
Bleomycin results in increased expression of GC protein |
CTD |
PMID:25933445 |
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NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
multiple interactions decreases expression |
ISO |
caffeic acid phenethyl ester inhibits the reaction [Bleomycin results in decreased expression of GCLC protein] |
CTD |
PMID:23570914 |
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NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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G |
Gda |
guanine deaminase |
decreases expression |
EXP |
Bleomycin results in decreased expression of GDA protein |
CTD |
PMID:25933445 |
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NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416
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G |
Glb1 |
galactosidase, beta 1 |
increases activity |
ISO |
Bleomycin results in increased activity of GLB1 protein |
CTD |
PMID:32554301 |
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NCBI chr 8:114,085,508...114,158,127
Ensembl chr 8:114,085,508...114,158,127
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G |
Gpi |
glucose-6-phosphate isomerase |
decreases expression |
EXP |
Bleomycin results in decreased expression of GPI protein |
CTD |
PMID:25933445 |
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NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086
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G |
Gpx1 |
glutathione peroxidase 1 |
affects expression |
EXP |
Bleomycin affects the expression of GPX1 protein |
CTD |
PMID:25933445 |
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NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
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G |
Gria2 |
glutamate ionotropic receptor AMPA type subunit 2 |
decreases expression |
EXP |
Bleomycin results in decreased expression of GRIA2 mRNA |
CTD |
PMID:15808516 |
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NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510
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G |
Grik3 |
glutamate ionotropic receptor kainate type subunit 3 |
decreases expression |
EXP |
Bleomycin results in decreased expression of GRIK3 mRNA |
CTD |
PMID:15808516 |
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NCBI chr 5:137,767,865...137,989,617
Ensembl chr 5:137,767,865...137,984,307
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G |
Grpr |
gastrin releasing peptide receptor |
decreases expression |
EXP |
Bleomycin results in decreased expression of GRPR mRNA |
CTD |
PMID:15808516 |
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NCBI chr X:30,998,425...31,038,442
Ensembl chr X:30,998,416...31,038,442
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions increases phosphorylation |
ISO |
[2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of GSK3B protein] which results in decreased susceptibility to Bleomycin; [Bleomycin results in increased phosphorylation of GSK3B protein] inhibits the reaction [GSK3B protein binds to and results in increased stability of NFKBIA protein] |
CTD |
PMID:19429264 |
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NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
Gsn |
gelsolin |
decreases expression |
EXP |
Bleomycin results in decreased expression of GSN protein |
CTD |
PMID:25933445 |
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NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
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G |
Gsr |
glutathione-disulfide reductase |
decreases activity multiple interactions |
EXP |
Bleomycin results in decreased activity of GSR protein celastrol inhibits the reaction [Bleomycin results in decreased activity of GSR protein] |
CTD |
PMID:26768587 |
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NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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G |
Gstm1 |
glutathione S-transferase mu 1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of GSTM1 protein |
CTD |
PMID:25933445 |
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NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
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G |
H1f0 |
H1.0 linker histone |
affects expression |
EXP |
Bleomycin affects the expression of H1F0 protein |
CTD |
PMID:25933445 |
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NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694
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G |
H1f4 |
H1.4 linker histone, cluster member |
affects expression |
EXP |
Bleomycin affects the expression of H1F4 protein |
CTD |
PMID:25933445 |
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NCBI chr17:41,486,574...41,487,355
Ensembl chr17:41,486,560...41,487,403
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G |
H2ax |
H2A.X variant histone |
increases expression |
ISO |
Bleomycin results in increased expression of H2AX protein |
CTD |
PMID:25130544 |
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NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
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G |
Hadha |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha |
decreases expression |
EXP |
Bleomycin results in decreased expression of HADHA protein |
CTD |
PMID:25933445 |
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NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
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G |
Havcr1 |
hepatitis A virus cellular receptor 1 |
increases expression |
ISO |
Bleomycin results in increased expression of HAVCR1 protein |
CTD |
PMID:29175452 |
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NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
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G |
Hbb |
hemoglobin subunit beta |
affects expression |
EXP |
Bleomycin affects the expression of HBB protein |
CTD |
PMID:25933445 |
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NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012
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G |
Hbb-b2 |
hemoglobin, beta adult minor chain |
affects expression |
EXP |
Bleomycin affects the expression of HBB-B2 protein |
CTD |
PMID:25933445 |
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NCBI chr 1:158,243,696...158,245,076
Ensembl chr 1:158,120,200...158,252,012
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G |
Hbegf |
heparin-binding EGF-like growth factor |
increases expression |
ISO |
Bleomycin results in increased expression of HBEGF mRNA |
CTD |
PMID:18684396 |
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NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
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G |
Hcls1 |
hematopoietic cell specific Lyn substrate 1 |
multiple interactions increases expression |
ISO |
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of HCLS1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of HCLS1 mRNA] |
CTD |
PMID:30825431 |
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NCBI chr11:63,817,482...63,840,943
Ensembl chr11:63,817,476...63,841,014
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G |
Hgf |
hepatocyte growth factor |
decreases expression multiple interactions increases expression increases secretion |
EXP ISO |
Bleomycin results in decreased expression of HGF mRNA; Bleomycin results in decreased expression of HGF protein Berberine inhibits the reaction [Bleomycin results in decreased expression of HGF mRNA]; Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of HGF protein]; lenabasum promotes the reaction [Bleomycin results in decreased expression of HGF protein] Bleomycin results in increased expression of HGF mRNA Bleomycin results in increased secretion of HGF protein Valsartan inhibits the reaction [Bleomycin results in decreased expression of HGF mRNA]; Valsartan inhibits the reaction [Bleomycin results in decreased expression of HGF protein] |
CTD |
PMID:16115399 PMID:22687607 PMID:29408570 PMID:30825431 |
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NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
multiple interactions increases expression |
ISO |
[HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; Dinoprostone inhibits the reaction [Bleomycin results in increased expression of HIF1A mRNA]; HIF1A protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]] |
CTD |
PMID:28434932 |
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NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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G |
Hist1h2bg |
histone cluster 1, H2bg |
decreases expression |
EXP |
Bleomycin results in decreased expression of HIST1H2BG protein |
CTD |
PMID:25933445 |
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NCBI chr17:41,571,234...41,572,202
Ensembl chr17:41,571,210...41,571,896
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G |
Hmces |
5-hydroxymethylcytosine binding, ES cell specific |
decreases expression |
ISO |
Bleomycin results in decreased expression of HMCES mRNA |
CTD |
PMID:33770205 |
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NCBI chr 4:120,392,812...120,415,616
Ensembl chr 4:120,366,542...120,415,616
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G |
Hmgb1 |
high mobility group box 1 |
multiple interactions increases expression |
EXP ISO |
protocatechualdehyde inhibits the reaction [Bleomycin results in increased expression of HMGB1 protein] Bleomycin inhibits the reaction [Azacitidine results in decreased expression of and results in increased secretion of HMGB1 protein]; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of HMGB1 mRNA] |
CTD |
PMID:25582705 PMID:32278510 |
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NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565 Ensembl chr16:5,901,586...5,978,565
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G |
Hmox1 |
heme oxygenase 1 |
increases expression multiple interactions decreases expression |
ISO EXP |
Bleomycin results in increased expression of HMOX1 protein celastrol inhibits the reaction [Bleomycin results in decreased expression of HMOX1 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of HMOX1 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of HMOX1 mRNA] PPARA protein affects the reaction [Bleomycin results in increased expression of HMOX1 protein] |
CTD |
PMID:16317386 PMID:26093215 PMID:26768587 |
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hnrnpa2b1 |
heterogeneous nuclear ribonucleoprotein A2/B1 |
increases expression |
EXP |
Bleomycin results in increased expression of HNRNPA2B1 protein |
CTD |
PMID:25933445 |
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NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249
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G |
Hnrnpa3 |
heterogeneous nuclear ribonucleoprotein A3 |
increases expression |
EXP |
Bleomycin results in increased expression of HNRNPA3 protein |
CTD |
PMID:25933445 |
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NCBI chr 3:60,578,574...60,588,755
Ensembl chr 3:60,578,673...60,588,306
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G |
Hpx |
hemopexin |
increases expression |
EXP |
Bleomycin results in increased expression of HPX protein |
CTD |
PMID:25933445 |
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NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328
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G |
Hsp90aa1 |
heat shock protein 90 alpha family class A member 1 |
multiple interactions |
EXP |
[Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of HSP90AA1 protein |
CTD |
PMID:24478030 |
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NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
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G |
Hsp90b1 |
heat shock protein 90 beta family member 1 |
multiple interactions |
EXP |
[Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of HSP90B1 protein |
CTD |
PMID:24478030 |
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NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
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G |
Hspa1a |
heat shock protein family A (Hsp70) member 1A |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of HSPA1A mRNA geranylgeranylacetone promotes the reaction [Bleomycin results in increased expression of HSPA1A mRNA] |
CTD |
PMID:37307957 |
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NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
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G |
Hspa1b |
heat shock protein family A (Hsp70) member 1B |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of HSPA1B mRNA geranylgeranylacetone promotes the reaction [Bleomycin results in increased expression of HSPA1B mRNA] |
CTD |
PMID:37307957 |
|
NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240 Ensembl chr20:3,856,006...3,873,240
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
increases expression multiple interactions |
EXP |
Bleomycin results in increased expression of HSPA5 protein pachymic acid inhibits the reaction [Bleomycin results in increased expression of HSPA5 protein] |
CTD |
PMID:25933445 PMID:37163307 |
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NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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G |
Hspb1 |
heat shock protein family B (small) member 1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of HSPB1 protein |
CTD |
PMID:25933445 |
|
NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
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G |
Hspe1 |
heat shock protein family E (Hsp10) member 1 |
increases expression |
EXP ISO |
Bleomycin results in increased expression of HSPE1 protein |
CTD |
PMID:25933445 PMID:29733421 |
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NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089
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G |
Htr1f |
5-hydroxytryptamine receptor 1F |
decreases expression |
EXP |
Bleomycin results in decreased expression of HTR1F mRNA |
CTD |
PMID:15808516 |
|
NCBI chr11:2,642,751...2,644,150
Ensembl chr11:2,642,751...2,644,150
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G |
Htr5a |
5-hydroxytryptamine receptor 5A |
decreases expression |
EXP |
Bleomycin results in decreased expression of HTR5A mRNA |
CTD |
PMID:15808516 |
|
NCBI chr 4:7,444,968...7,454,651
Ensembl chr 4:7,444,968...7,454,651
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G |
Htr5b |
5-hydroxytryptamine (serotonin) receptor 5B |
decreases expression |
EXP |
Bleomycin results in decreased expression of HTR5B mRNA |
CTD |
PMID:15808516 |
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NCBI chr13:32,686,911...32,699,835
Ensembl chr13:32,687,042...32,699,835
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G |
Icam1 |
intercellular adhesion molecule 1 |
increases expression |
ISO |
Bleomycin results in increased expression of ICAM1 mRNA |
CTD |
PMID:29033951 PMID:29720568 |
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NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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G |
Idh2 |
isocitrate dehydrogenase (NADP(+)) 2 |
decreases expression |
EXP |
Bleomycin results in decreased expression of IDH2 protein |
CTD |
PMID:25933445 |
|
NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
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G |
Ifitm1 |
interferon induced transmembrane protein 1 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of IFITM1 mRNA Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of IFITM1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of IFITM1 mRNA] |
CTD |
PMID:30825431 |
|
NCBI chr 1:196,067,163...196,069,169
Ensembl chr 1:196,067,963...196,069,169
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G |
Ifng |
interferon gamma |
increases expression multiple interactions decreases expression |
ISO EXP |
Bleomycin results in increased expression of IFNG mRNA [Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of IFNG protein Bleomycin results in decreased expression of IFNG protein [SPL-334 co-treated with Bleomycin] results in increased expression of IFNG protein Bleomycin results in decreased expression of IFNG mRNA |
CTD |
PMID:11350791 PMID:25071917 PMID:26209236 PMID:29408570 PMID:33516805 PMID:36087614 More...
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NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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G |
Igf1 |
insulin-like growth factor 1 |
increases expression |
ISO |
Bleomycin results in increased expression of IGF1 mRNA |
CTD |
PMID:1705203 |
|
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
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G |
Ikbip |
IKBKB interacting protein |
increases expression |
ISO |
Bleomycin results in increased expression of IKBIP mRNA |
CTD |
PMID:36087614 |
|
NCBI chr 7:25,579,865...25,598,548
Ensembl chr 7:25,579,832...25,605,162
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G |
Il10 |
interleukin 10 |
increases expression increases secretion multiple interactions |
ISO |
Bleomycin results in increased expression of IL10 protein Bleomycin results in increased secretion of IL10 protein yupingfeng inhibits the reaction [Bleomycin results in increased secretion of IL10 protein] |
CTD |
PMID:29175452 PMID:37898439 |
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NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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G |
Il10ra |
interleukin 10 receptor subunit alpha |
increases expression |
ISO |
Bleomycin results in increased expression of IL10RA mRNA |
CTD |
PMID:36087614 |
|
NCBI chr 8:45,563,009...45,578,041
Ensembl chr 8:45,563,137...45,578,061
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G |
Il12b |
interleukin 12B |
increases expression |
ISO |
Bleomycin results in increased expression of IL12B mRNA; Bleomycin results in increased expression of IL12B protein |
CTD |
PMID:11350791 |
|
NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
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G |
Il12rb2 |
interleukin 12 receptor subunit beta 2 |
increases expression |
ISO |
Bleomycin results in increased expression of IL12RB2 mRNA |
CTD |
PMID:11350791 |
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NCBI chr 4:96,426,396...96,515,251
Ensembl chr 4:96,426,842...96,515,289
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G |
Il13 |
interleukin 13 |
decreases response to substance multiple interactions |
ISO |
IL13 gene mutant form results in decreased susceptibility to Bleomycin IL13 protein affects the reaction [Bleomycin results in increased expression of RETNLA mRNA] |
CTD |
PMID:15322207 |
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NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
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G |
Il13ra1 |
interleukin 13 receptor subunit alpha 1 |
multiple interactions increases expression |
ISO |
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of IL13RA1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of IL13RA1 mRNA] |
CTD |
PMID:30825431 PMID:36087614 |
|
NCBI chr X:115,348,822...115,408,682
Ensembl chr X:115,348,860...115,408,681 Ensembl chr11:115,348,860...115,408,681
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G |
Il17a |
interleukin 17A |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Bleomycin results in increased expression of IL17A mRNA] |
CTD |
PMID:35716765 |
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NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
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G |
Il17rd |
interleukin 17 receptor D |
increases expression |
ISO |
Bleomycin results in increased expression of IL17RD mRNA |
CTD |
PMID:36087614 |
|
NCBI chr16:2,228,438...2,295,122
Ensembl chr16:2,228,287...2,292,556
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G |
Il17re |
interleukin 17 receptor E |
increases expression |
ISO |
Bleomycin results in increased expression of IL17RE mRNA |
CTD |
PMID:36087614 |
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NCBI chr 4:146,604,547...146,618,206
Ensembl chr 4:146,605,526...146,618,206
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G |
Il1a |
interleukin 1 alpha |
multiple interactions increases expression |
ISO |
5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Bleomycin results in increased expression of IL1A mRNA]; Apigenin inhibits the reaction [Bleomycin results in increased expression of IL1A mRNA]; IL1A protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; IL1A protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; IL1A protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein] Bleomycin results in increased expression of IL1A protein |
CTD |
PMID:8317554 PMID:29175452 PMID:32554301 |
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NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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G |
Il1b |
interleukin 1 beta |
multiple interactions increases expression increases secretion affects expression |
ISO EXP |
12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; [Bleomycin co-treated with Cannabidiol analog] results in decreased expression of IL1B mRNA; [Bleomycin co-treated with Rosiglitazone] results in decreased expression of IL1B mRNA; Calcitriol inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of IL1B mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; honokiol inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; pirinixic acid inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; PPARA protein affects the reaction [Bleomycin results in increased expression of IL1B protein]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; SLCO2A1 gene mutant form promotes the reaction [Bleomycin results in increased expression of IL1B mRNA]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of IL1B protein]; verlukast inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; zileuton inhibits the reaction [Bleomycin results in increased expression of IL1B protein] Bleomycin affects the expression of IL1B mRNA 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; Apigenin inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; IL1B protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]; yupingfeng inhibits the reaction [Bleomycin results in increased secretion of IL1B protein] Bleomycin results in increased expression of IL1B mRNA; Bleomycin results in increased expression of IL1B protein Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; Resveratrol inhibits the reaction [Bleomycin results in increased expression of IL1B protein] |
CTD |
PMID:8317554 PMID:8473757 PMID:16317386 PMID:17035056 PMID:17118201 PMID:17177178 PMID:19147827 PMID:22687607 PMID:26093215 PMID:26520185 PMID:26526764 PMID:26600069 PMID:27704718 PMID:28300665 PMID:28694203 PMID:30033591 PMID:32032644 PMID:32554301 PMID:32828905 PMID:35267148 PMID:36087614 PMID:37898439 More...
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il1rl1 |
interleukin 1 receptor-like 1 |
increases expression |
ISO |
Bleomycin results in increased expression of IL1RL1 mRNA; Bleomycin results in increased expression of IL1RL1 protein |
CTD |
PMID:37399107 |
|
NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256
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G |
Il2 |
interleukin 2 |
multiple interactions |
EXP |
[Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of IL2 protein |
CTD |
PMID:33516805 |
|
NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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G |
Il33 |
interleukin 33 |
increases expression |
ISO |
Bleomycin results in increased expression of IL33 mRNA; Bleomycin results in increased expression of IL33 protein |
CTD |
PMID:36087614 PMID:37399107 |
|
NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
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G |
Il4 |
interleukin 4 |
increases expression multiple interactions increases secretion affects response to substance decreases response to substance |
ISO |
Bleomycin results in increased expression of IL4 mRNA yupingfeng inhibits the reaction [Bleomycin results in increased secretion of IL4 protein] IL4 protein affects the susceptibility to Bleomycin Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of IL4 mRNA]; IL4 protein affects the reaction [Bleomycin results in increased expression of RETNLA mRNA]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of IL4 mRNA] IL4 gene mutant form results in decreased susceptibility to Bleomycin |
CTD |
PMID:11554783 PMID:12574379 PMID:15322207 PMID:30033591 PMID:37898439 |
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NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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G |
Il6 |
interleukin 6 |
increases expression multiple interactions increases secretion |
ISO EXP |
Bleomycin results in increased expression of IL6 mRNA; Bleomycin results in increased expression of IL6 protein 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Apigenin inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Ephedrine inhibits the reaction [Bleomycin results in increased secretion of IL6 protein] Calcitriol inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of IL6 protein]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; honokiol inhibits the reaction [Bleomycin results in increased expression of IL6 protein]; Oils, Volatile inhibits the reaction [Bleomycin results in increased expression of IL6 protein]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; SPL-334 inhibits the reaction [Bleomycin results in increased expression of IL6 protein] allyl sulfide inhibits the reaction [Bleomycin results in increased expression of IL6 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; resveratrol inhibits the reaction [Bleomycin results in increased expression of IL6 protein] |
CTD |
PMID:17035056 PMID:18684396 PMID:23656969 PMID:25071917 PMID:26093215 PMID:26209236 PMID:26520185 PMID:28300665 PMID:28850077 PMID:30033591 PMID:32032644 PMID:32554301 PMID:35267148 PMID:35716765 PMID:36087614 PMID:37778983 More...
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Il7 |
interleukin 7 |
increases expression |
ISO |
Bleomycin results in increased expression of IL7 protein |
CTD |
PMID:36087614 |
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NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075
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G |
Insig1 |
insulin induced gene 1 |
multiple interactions decreases expression |
ISO |
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of INSIG1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of INSIG1 mRNA] |
CTD |
PMID:30825431 |
|
NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
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G |
Itgb2 |
integrin subunit beta 2 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of ITGB2 mRNA Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of ITGB2 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of ITGB2 mRNA] |
CTD |
PMID:30825431 |
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NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600
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G |
Jpt1 |
Jupiter microtubule associated homolog 1 |
increases expression |
EXP |
Bleomycin results in increased expression of JPT1 protein |
CTD |
PMID:25933445 |
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NCBI chr10:100,744,468...100,762,504
Ensembl chr10:100,686,797...100,784,513
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
increases activity multiple interactions increases phosphorylation |
ISO |
Bleomycin results in increased activity of JUN protein Bleomycin results in increased expression of [JUN protein binds to FOS protein]; Curcumin inhibits the reaction [Bleomycin results in increased phosphorylation of JUN protein] |
CTD |
PMID:12003776 PMID:35716765 PMID:37399107 |
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NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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G |
Keap1 |
Kelch-like ECH-associated protein 1 |
decreases expression increases expression multiple interactions |
EXP ISO |
Bleomycin results in decreased expression of KEAP1 protein Bleomycin results in increased expression of KEAP1 protein Ephedrine inhibits the reaction [Bleomycin results in increased expression of KEAP1 protein] celastrol inhibits the reaction [Bleomycin results in decreased expression of KEAP1 protein] |
CTD |
PMID:26768587 PMID:37778983 |
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NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
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G |
Khsrp |
KH-type splicing regulatory protein |
increases expression |
EXP |
Bleomycin results in increased expression of KHSRP protein |
CTD |
PMID:25933445 |
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NCBI chr 9:1,862,555...1,872,403
Ensembl chr 9:1,862,899...1,872,451
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G |
Kit |
KIT proto-oncogene receptor tyrosine kinase |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of KIT protein [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in increased expression of KIT protein |
CTD |
PMID:29733421 |
|
NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
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G |
Kl |
Klotho |
decreases expression |
ISO |
Bleomycin results in decreased expression of KL mRNA |
CTD |
PMID:29408570 |
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NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080
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G |
Klhl42 |
kelch-like family, member 42 |
increases expression |
ISO |
Bleomycin results in increased expression of KLHL42 mRNA |
CTD |
PMID:33770205 |
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NCBI chr 4:179,999,655...180,027,283
Ensembl chr 4:180,004,580...180,027,283
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G |
Kras |
KRAS proto-oncogene, GTPase |
multiple interactions |
ISO |
[Bleomycin co-treated with 1-nitropyrene] results in increased mutagenesis of KRAS gene |
CTD |
PMID:12616606 |
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NCBI chr 4:178,185,418...178,218,484
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G |
Krt13 |
keratin 13 |
increases expression |
ISO |
Bleomycin results in increased expression of KRT13 mRNA |
CTD |
PMID:36087614 |
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NCBI chr10:85,051,887...85,056,099
Ensembl chr10:85,051,889...85,056,084
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G |
Krt19 |
keratin 19 |
decreases expression |
EXP |
Bleomycin results in decreased expression of KRT19 protein |
CTD |
PMID:25933445 |
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NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799
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G |
Krt8 |
keratin 8 |
multiple interactions decreases expression |
ISO |
Ephedrine inhibits the reaction [Bleomycin results in decreased expression of KRT8 mRNA]; Ephedrine inhibits the reaction [Bleomycin results in decreased expression of KRT8 protein] Bleomycin results in decreased expression of KRT8 mRNA; Bleomycin results in decreased expression of KRT8 protein |
CTD |
PMID:37778983 |
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NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
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G |
Krt87 |
keratin 87 |
increases expression |
ISO |
Bleomycin results in increased expression of KRT87 mRNA |
CTD |
PMID:36087614 |
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NCBI chr 7:132,547,388...132,555,005
Ensembl chr 7:132,548,141...132,554,978
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G |
Lap3 |
leucine aminopeptidase 3 |
increases expression |
EXP |
Bleomycin results in increased expression of LAP3 protein |
CTD |
PMID:25933445 |
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NCBI chr14:65,608,375...65,627,359
Ensembl chr14:65,608,376...65,627,359
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G |
Lasp1 |
LIM and SH3 protein 1 |
increases expression |
EXP |
Bleomycin results in increased expression of LASP1 protein |
CTD |
PMID:25933445 |
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NCBI chr10:82,795,177...82,835,659
Ensembl chr10:82,795,137...82,943,292
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G |
Lcn2 |
lipocalin 2 |
increases expression |
ISO |
Bleomycin results in increased expression of LCN2 mRNA; Bleomycin results in increased expression of LCN2 protein |
CTD |
PMID:26345256 |
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NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
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G |
Lcp1 |
lymphocyte cytosolic protein 1 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of LCP1 mRNA Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of LCP1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of LCP1 mRNA] |
CTD |
PMID:30825431 |
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NCBI chr15:50,443,300...50,544,682
Ensembl chr15:50,488,149...50,544,680
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G |
Ldhal1 |
lactate dehydrogenase A like 1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of LDHAL1 protein |
CTD |
PMID:25933445 |
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NCBI chr 8:30,363,220...30,364,836
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G |
Lep |
leptin |
increases expression |
ISO |
Bleomycin results in increased expression of LEP protein |
CTD |
PMID:29175452 |
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NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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G |
Lgals3 |
galectin 3 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of LGALS3 protein NOS2 protein affects the reaction [Bleomycin results in increased expression of LGALS3 protein] |
CTD |
PMID:26526764 |
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NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
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G |
Lgals9 |
galectin 9 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of LGALS9 mRNA Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of LGALS9 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of LGALS9 mRNA] |
CTD |
PMID:30825431 |
|
NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
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G |
Lhb |
luteinizing hormone subunit beta |
multiple interactions increases expression |
ISO |
thymoquinone inhibits the reaction [Bleomycin results in increased expression of LHB protein] |
CTD |
PMID:34818114 |
|
NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
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Lhfpl6 |
LHFPL tetraspan subfamily member 6 |
multiple interactions decreases expression |
ISO |
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of LHFPL6 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of LHFPL6 mRNA] |
CTD |
PMID:30825431 |
|
NCBI chr 2:137,126,485...137,324,442
Ensembl chr 2:137,126,509...137,324,443
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G |
Lhx1 |
LIM homeobox 1 |
multiple interactions |
ISO |
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of LHX1 mRNA |
CTD |
PMID:29733421 |
|
NCBI chr10:69,396,829...69,403,617
Ensembl chr10:69,396,829...69,403,617
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G |
Liph |
lipase H |
decreases expression |
ISO |
Bleomycin results in decreased expression of LIPH mRNA |
CTD |
PMID:33770205 |
|
NCBI chr11:79,032,229...79,081,625
Ensembl chr11:79,033,312...79,081,625
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G |
Lmna |
lamin A/C |
increases expression |
EXP |
Bleomycin results in increased expression of LMNA protein |
CTD |
PMID:25933445 |
|
NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423
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G |
Lpxn |
leupaxin |
multiple interactions increases expression |
ISO |
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of LPXN mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of LPXN mRNA] |
CTD |
PMID:30825431 |
|
NCBI chr 1:209,928,297...209,963,085
Ensembl chr 1:209,929,202...209,963,084
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G |
Lyz2 |
lysozyme 2 |
decreases expression |
EXP |
Bleomycin results in decreased expression of LYZ protein |
CTD |
PMID:25933445 |
|
NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106
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Macroh2a1 |
macroH2A.1 histone |
decreases expression |
EXP |
Bleomycin results in decreased expression of MACROH2A1 protein |
CTD |
PMID:25933445 |
|
NCBI chr17:8,479,331...8,542,071
Ensembl chr17:8,479,372...8,542,072
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G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of MAP1LC3B protein modified form Soot inhibits the reaction [Bleomycin results in increased expression of MAP1LC3B protein modified form] |
CTD |
PMID:31302203 |
|
NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions |
ISO |
Bleomycin results in increased phosphorylation of and results in increased activity of MAPK1 protein; U 0126 inhibits the reaction [Bleomycin results in increased phosphorylation of and results in increased activity of MAPK1 protein] |
CTD |
PMID:23570914 |
|
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions |
ISO |
Bleomycin results in increased phosphorylation of and results in increased activity of MAPK3 protein; U 0126 inhibits the reaction [Bleomycin results in increased phosphorylation of and results in increased activity of MAPK3 protein] |
CTD |
PMID:23570914 |
|
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions increases phosphorylation |
ISO |
Curcumin inhibits the reaction [Bleomycin results in increased phosphorylation of MAPK8 protein] |
CTD |
PMID:35716765 |
|
NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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G |
Marcks |
myristoylated alanine rich protein kinase C substrate |
decreases expression |
EXP |
Bleomycin results in decreased expression of MARCKS protein |
CTD |
PMID:25933445 |
|
NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012
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G |
Mdh2 |
malate dehydrogenase 2 |
decreases expression multiple interactions |
EXP ISO |
Bleomycin results in decreased expression of MDH2 protein [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of MDH2 protein |
CTD |
PMID:25933445 PMID:29733421 |
|
NCBI chr12:20,894,269...20,907,225
Ensembl chr12:20,894,262...20,907,271
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G |
Mecp2 |
methyl CpG binding protein 2 |
affects response to substance |
ISO |
MECP2 protein affects the susceptibility to Bleomycin |
CTD |
PMID:21435439 |
|
NCBI chr X:151,781,177...151,844,687
Ensembl chr X:151,789,930...151,844,689
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G |
Mepce |
methylphosphate capping enzyme |
increases expression |
ISO |
Bleomycin results in increased expression of MEPCE mRNA |
CTD |
PMID:33770205 |
|
NCBI chr12:18,911,796...18,916,515
Ensembl chr12:18,911,796...18,916,514
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G |
Mertk |
MER proto-oncogene, tyrosine kinase |
multiple interactions increases phosphorylation |
ISO |
Bleomycin affects the localization of and affects the expression of MERTK protein Bleomycin results in increased phosphorylation of MERTK protein |
CTD |
PMID:22687607 |
|
NCBI chr 3:115,939,351...116,045,141
Ensembl chr 3:115,939,351...116,046,554
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G |
Mfn1 |
mitofusin 1 |
decreases expression |
ISO |
Bleomycin results in decreased expression of MFN1 protein |
CTD |
PMID:37126650 |
|
NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640
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G |
Mfn2 |
mitofusin 2 |
decreases expression |
ISO |
Bleomycin results in decreased expression of MFN2 protein |
CTD |
PMID:37126650 |
|
NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
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G |
Mif |
macrophage migration inhibitory factor |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIF protein |
CTD |
PMID:25933445 |
|
NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
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G |
Mir100 |
microRNA 100 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR100 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 8:41,901,225...41,901,304
Ensembl chr 8:41,901,225...41,901,304
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G |
Mir101-2 |
microRNA 101-2 |
decreases expression |
EXP ISO |
Bleomycin results in decreased expression of MIR101B mRNA |
CTD |
PMID:25933445 PMID:28726637 |
|
NCBI chr 1:226,860,371...226,860,467
Ensembl chr 1:226,860,371...226,860,467
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G |
Mir101a |
microRNA 101a |
multiple interactions decreases expression |
ISO EXP |
MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL3A1 mRNA]; MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of FZD6 mRNA]; MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of NFATC2 mRNA]; MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of TGFBR1 mRNA] Bleomycin results in decreased expression of MIR101A mRNA |
CTD |
PMID:25933445 PMID:28726637 |
|
NCBI chr 5:115,966,332...115,966,406
Ensembl chr 5:115,966,328...115,966,410
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G |
Mir106b |
microRNA 106b |
affects expression |
EXP |
Bleomycin affects the expression of MIR106B mRNA |
CTD |
PMID:25933445 |
|
NCBI chr12:17,043,344...17,043,425
Ensembl chr12:17,043,344...17,043,425
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G |
Mir107 |
microRNA 107 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR107 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 1:232,337,767...232,337,853
Ensembl chr 1:232,337,767...232,337,853
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G |
Mir10a |
microRNA 10a |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR10A mRNA |
CTD |
PMID:25933445 |
|
NCBI chr10:81,283,171...81,283,280
Ensembl chr10:81,283,171...81,283,280
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G |
Mir10b |
microRNA 10b |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR10B mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 3:59,628,438...59,628,546
Ensembl chr 3:59,628,438...59,628,546
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G |
Mir1224 |
microRNA 1224 |
increases expression |
EXP |
Bleomycin results in increased expression of MIR1224 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr11:80,306,902...80,306,986
Ensembl chr11:80,306,902...80,306,986
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G |
Mir1249 |
microRNA 1249 |
affects expression |
EXP |
Bleomycin affects the expression of MIR1249 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 7:116,075,593...116,075,712
Ensembl chr 7:116,075,593...116,075,712
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G |
Mir125a |
microRNA 125a |
affects expression |
EXP |
Bleomycin affects the expression of MIR125A mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 1:58,677,626...58,677,710
Ensembl chr 1:58,677,626...58,677,710
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G |
Mir126a |
microRNA 126a |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR126 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 3:9,415,063...9,415,180
Ensembl chr 3:9,415,063...9,415,180
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G |
Mir130a |
microRNA 130a |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR130A mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 3:69,822,542...69,822,629
Ensembl chr 3:69,822,542...69,822,629
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G |
Mir133a1 |
microRNA 133a-1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR133A1 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr18:1,885,082...1,885,168
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G |
Mir133b |
microRNA 133b |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR133B mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 9:23,098,134...23,098,217
Ensembl chr 9:23,098,134...23,098,217
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G |
Mir140 |
microRNA 140 |
affects expression |
EXP |
Bleomycin affects the expression of MIR140 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr19:35,465,577...35,465,675
Ensembl chr19:35,465,577...35,465,675
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G |
Mir141 |
microRNA 141 |
affects expression |
EXP |
Bleomycin affects the expression of MIR141 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 4:157,523,239...157,523,332
Ensembl chr 4:157,523,239...157,523,332
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G |
Mir142 |
microRNA 142 |
decreases expression increases expression |
EXP |
Bleomycin results in decreased expression of MIR142 mRNA Bleomycin results in increased expression of MIR142 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr10:72,557,864...72,557,950
Ensembl chr10:72,557,857...72,557,967
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G |
Mir143 |
microRNA 143 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR143 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr18:55,101,006...55,101,110
Ensembl chr18:55,101,006...55,101,110
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G |
Mir144 |
microRNA 144 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR144 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr10:62,961,348...62,961,430
Ensembl chr10:62,961,348...62,961,430
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G |
Mir145 |
microRNA 145 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR145 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727
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G |
Mir146a |
microRNA 146a |
affects expression |
EXP |
Bleomycin affects the expression of MIR146A mRNA |
CTD |
PMID:25933445 |
|
NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610
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G |
Mir146b |
microRNA 146b |
increases expression |
EXP |
Bleomycin results in increased expression of MIR146B mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 1:245,203,438...245,203,525
Ensembl chr 1:245,203,438...245,203,525
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G |
Mir148b |
microRNA 148b |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR148B mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 7:134,421,398...134,421,494
Ensembl chr 7:134,421,398...134,421,494
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G |
Mir150 |
microRNA 150 |
affects expression |
EXP |
Bleomycin affects the expression of MIR150 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 1:95,605,024...95,605,108
Ensembl chr 1:95,605,024...95,605,108
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G |
Mir151 |
microRNA 151 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR151 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 7:105,172,377...105,172,473
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G |
Mir152 |
microRNA 152 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR152 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr10:81,832,936...81,833,020
Ensembl chr10:81,832,936...81,833,020
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G |
Mir15b |
microRNA 15b |
affects expression |
EXP |
Bleomycin affects the expression of MIR15B mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 2:153,245,200...153,245,297
Ensembl chr 2:153,245,200...153,245,297
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G |
Mir16 |
microRNA 16 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR16 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 2:153,245,349...153,245,443
Ensembl chr 2:153,245,349...153,245,443
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G |
Mir17 |
microRNA 17 |
affects expression |
EXP |
Bleomycin affects the expression of MIR17 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712
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G |
Mir181c |
microRNA 181c |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR181C mRNA |
CTD |
PMID:25933445 |
|
NCBI chr19:23,983,523...23,983,628
Ensembl chr19:23,983,523...23,983,628
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G |
Mir181d |
microRNA 181d |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR181D mRNA |
CTD |
PMID:25933445 |
|
NCBI chr19:23,983,706...23,983,788
Ensembl chr19:23,983,706...23,983,788
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G |
Mir183 |
microRNA 183 |
affects expression |
EXP |
Bleomycin affects the expression of MIR183 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 4:58,788,614...58,788,723
Ensembl chr 4:58,788,614...58,788,723
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G |
Mir185 |
microRNA 185 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR185 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr11:82,664,716...82,664,795
Ensembl chr11:82,664,716...82,664,795
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G |
Mir186 |
microRNA 186 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR186 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 2:246,582,806...246,582,891
Ensembl chr 2:246,582,806...246,582,891
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G |
Mir188 |
microRNA 188 |
affects expression |
EXP |
Bleomycin affects the expression of MIR188 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr X:15,247,715...15,247,794
Ensembl chr X:15,247,715...15,247,794
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G |
Mir18a |
microRNA 18a |
increases expression |
EXP |
Bleomycin results in increased expression of MIR18A mRNA |
CTD |
PMID:25933445 |
|
NCBI chr15:92,180,765...92,180,860
Ensembl chr15:92,180,765...92,180,860
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G |
Mir193 |
microRNA 193 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR193 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr10:64,672,354...64,672,439
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G |
Mir195 |
microRNA 195 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR195 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr10:54,951,838...54,951,924
Ensembl chr10:54,951,838...54,951,924
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G |
Mir199a2 |
microRNA 199a-2 |
affects expression |
EXP |
Bleomycin affects the expression of MIR199A2 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr13:74,582,954...74,583,063
Ensembl chr13:74,582,954...74,583,063
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G |
Mir19a |
microRNA 19a |
affects expression |
EXP |
Bleomycin affects the expression of MIR19A mRNA |
CTD |
PMID:25933445 |
|
NCBI chr15:92,180,912...92,180,993
Ensembl chr15:92,180,912...92,180,993
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G |
Mir200a |
microRNA 200a |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR200A mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 5:166,648,494...166,648,582
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G |
Mir200b |
microRNA 200b |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR200B mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 5:166,649,272...166,649,366
Ensembl chr 5:166,649,272...166,649,366
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G |
Mir200c |
microRNA 200c |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR200C mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 4:157,523,679...157,523,747
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G |
Mir204 |
microRNA 204 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR204 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 1:220,316,931...220,317,040
Ensembl chr 1:220,316,931...220,317,040
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G |
Mir20a |
microRNA 20a |
affects expression |
EXP |
Bleomycin affects the expression of MIR20A mRNA |
CTD |
PMID:25933445 |
|
NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168
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G |
Mir20b |
microRNA 20b |
affects expression |
EXP |
Bleomycin affects the expression of MIR20B mRNA |
CTD |
PMID:25933445 |
|
NCBI chr X:132,422,211...132,422,282
Ensembl chr X:132,422,211...132,422,282
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G |
Mir21 |
microRNA 21 |
increases expression |
EXP |
Bleomycin results in increased expression of MIR21 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
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G |
Mir210 |
microRNA 210 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR210 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454
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G |
Mir211 |
microRNA 211 |
affects expression |
EXP |
Bleomycin affects the expression of MIR211 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 1:117,777,539...117,777,644
Ensembl chr 1:117,777,539...117,777,644
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G |
Mir212 |
microRNA 212 |
affects expression |
EXP |
Bleomycin affects the expression of MIR212 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr10:60,023,403...60,023,513
Ensembl chr10:60,023,403...60,023,513
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G |
Mir214 |
microRNA 214 |
affects expression |
EXP |
Bleomycin affects the expression of MIR214 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr13:74,588,374...74,588,481
Ensembl chr13:74,588,372...74,588,481
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G |
Mir22 |
microRNA 22 |
affects expression |
EXP |
Bleomycin affects the expression of MIR22 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr10:60,307,039...60,307,133
Ensembl chr10:60,307,039...60,307,133
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G |
Mir221 |
microRNA 221 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR221 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr X:3,429,465...3,429,573
Ensembl chr X:3,429,465...3,429,573
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G |
Mir222 |
microRNA 222 |
decreases expression affects expression |
EXP |
Bleomycin results in decreased expression of MIR222 mRNA Bleomycin affects the expression of MIR222 mRNA |
CTD |
PMID:25933445 PMID:34425168 |
|
NCBI chr X:3,428,904...3,429,006
Ensembl chr X:3,428,904...3,429,006
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G |
Mir223 |
microRNA 223 |
affects expression |
EXP |
Bleomycin affects the expression of MIR223 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr X:61,141,887...61,141,996
Ensembl chr X:61,141,887...61,141,996
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G |
Mir23a |
microRNA 23a |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR23A mRNA |
CTD |
PMID:25933445 |
|
NCBI chr19:23,954,997...23,955,071
Ensembl chr19:23,954,997...23,955,071
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G |
Mir23b |
microRNA 23b |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR23B mRNA |
CTD |
PMID:25933445 |
|
NCBI chr17:1,813,667...1,813,763
Ensembl chr17:1,813,667...1,813,763
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G |
Mir24-2 |
microRNA 24-2 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR24-2 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr19:23,954,683...23,954,790
Ensembl chr19:23,954,683...23,954,790
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G |
Mir25 |
microRNA 25 |
affects expression |
EXP |
Bleomycin affects the expression of MIR25 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr12:17,042,932...17,043,015
Ensembl chr12:17,042,932...17,043,015
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G |
Mir26a |
microRNA 26a |
decreases expression |
EXP ISO |
Bleomycin results in decreased expression of MIR26A mRNA Bleomycin results in decreased expression of MIR26A-1 |
CTD |
PMID:25933445 PMID:35785413 |
|
NCBI chr 8:118,755,289...118,755,378
Ensembl chr 8:118,755,289...118,755,378
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Mir26b |
microRNA 26b |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR26B mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 9:75,976,596...75,976,680
Ensembl chr 9:75,976,596...75,976,680
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Mir27a |
microRNA 27a |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR27A mRNA |
CTD |
PMID:25933445 |
|
NCBI chr19:23,954,831...23,954,917
Ensembl chr19:23,954,831...23,954,917
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G |
Mir27b |
microRNA 27b |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR27B mRNA |
CTD |
PMID:25933445 |
|
NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529
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Mir28 |
microRNA 28 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR28 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr11:75,975,523...75,975,608
Ensembl chr11:75,975,523...75,975,608
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Mir290 |
microRNA 290 |
increases expression |
EXP |
Bleomycin results in increased expression of MIR290 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 1:65,964,648...65,964,728
Ensembl chr 1:65,964,648...65,964,728
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Mir296 |
microRNA 296 |
affects expression |
EXP |
Bleomycin affects the expression of MIR296 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 3:163,051,838...163,051,915
Ensembl chr 3:163,051,838...163,051,915
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G |
Mir2985 |
microRNA 2985 |
affects expression |
EXP |
Bleomycin affects the expression of MIR2985 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 2:165,956,389...165,956,498
Ensembl chr 2:165,956,389...165,956,498
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G |
Mir29a |
microRNA 29a |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR29A mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 4:59,650,608...59,650,695
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Mir301a |
microRNA 301a |
affects expression |
EXP |
Bleomycin affects the expression of MIR301A mRNA |
CTD |
PMID:25933445 |
|
NCBI chr10:71,925,336...71,925,435
Ensembl chr10:71,925,336...71,925,435
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G |
Mir30a |
microRNA 30a |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR30A mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 9:25,737,600...25,737,670
Ensembl chr 9:25,737,600...25,737,670
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G |
Mir30b |
microRNA 30b |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR30B mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 7:100,132,589...100,132,675
Ensembl chr 7:100,132,589...100,132,675
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G |
Mir30c2 |
microRNA 30c-2 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR30C2 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 9:25,757,342...25,757,425
Ensembl chr 9:25,757,342...25,757,425
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Mir30d |
microRNA 30d |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR30D mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 7:100,136,391...100,136,472
Ensembl chr 7:100,136,391...100,136,472
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Mir30e |
microRNA 30e |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR30E mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 5:134,352,232...134,352,323
Ensembl chr 5:134,352,232...134,352,323
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Mir31 |
microRNA 31 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR31 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 5:103,599,038...103,599,143
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Mir32 |
microRNA 32 |
increases expression |
EXP |
Bleomycin results in increased expression of MIR32 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 5:71,596,083...71,596,152
Ensembl chr 5:71,596,083...71,596,152
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Mir320a |
microRNA 320a |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR320A mRNA |
CTD |
PMID:25933445 |
|
NCBI chr15:45,516,392...45,516,473
Ensembl chr15:45,516,392...45,516,473
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Mir322 |
microRNA 322 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR322 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr X:132,806,594...132,806,688
Ensembl chr X:132,806,594...132,806,688
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Mir324 |
microRNA 324 |
affects expression |
EXP |
Bleomycin affects the expression of MIR324 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr10:54,734,680...54,734,762
Ensembl chr10:54,734,678...54,734,766
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Mir326 |
microRNA 326 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR326 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 1:153,854,029...153,854,123
Ensembl chr 1:153,854,029...153,854,123
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Mir328 |
microRNA 328 |
affects expression |
EXP |
Bleomycin affects the expression of MIR328 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr19:33,184,766...33,184,849
Ensembl chr19:33,184,766...33,184,849
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Mir33 |
microRNA 33 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR33 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 7:113,713,855...113,713,923
Ensembl chr 7:113,713,855...113,713,923
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Mir330 |
microRNA 330 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR330 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 1:78,833,178...78,833,274
Ensembl chr 1:78,833,178...78,833,274
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Mir331 |
microRNA 331 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR331 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 7:28,527,390...28,527,485
Ensembl chr 7:28,527,390...28,527,485
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Mir340-1 |
microRNA 340-1 |
increases expression |
EXP |
Bleomycin results in increased expression of MIR340-1 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr10:34,393,568...34,393,665
Ensembl chr10:34,393,568...34,393,665
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Mir342 |
microRNA 342 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR342 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 6:127,565,269...127,565,367
Ensembl chr 6:127,565,269...127,565,367
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Mir345 |
microRNA 345 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR345 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 6:127,754,027...127,754,122
Ensembl chr 6:127,754,027...127,754,122
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Mir347 |
microRNA mir-347 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR347 mRNA |
CTD |
PMID:25933445 |
|
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Mir3473 |
microRNA 3473 |
increases expression |
EXP |
Bleomycin results in increased expression of MIR3473 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr13:39,499,246...39,499,312
Ensembl chr13:39,499,246...39,499,312
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Mir34a |
microRNA 34a |
affects expression decreases expression |
EXP |
Bleomycin affects the expression of MIR34A mRNA Bleomycin results in decreased expression of MIR34A mRNA |
CTD |
PMID:25933445 PMID:34425168 |
|
NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103
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Mir34b |
microRNA 34b |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR34B mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 8:51,410,244...51,410,327
Ensembl chr 8:51,410,244...51,410,327
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Mir34c |
microRNA 34c |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR34C mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 8:51,409,726...51,409,802
Ensembl chr 8:51,409,726...51,409,802
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Mir352 |
microRNA mir-352 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR352 mRNA |
CTD |
PMID:25933445 |
|
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Mir3545 |
microRNA 3545 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR203 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 6:131,199,542...131,199,656
Ensembl chr 6:131,199,542...131,199,656
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Mir3573 |
microRNA 3573 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR3573 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr X:64,259,096...64,259,167
Ensembl chr X:64,259,096...64,259,167
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Mir3584 |
microRNA 3584 |
affects expression |
EXP |
Bleomycin affects the expression of MIR3584 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 1:246,786,249...246,786,329
Ensembl chr 1:246,786,249...246,786,329
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Mir361 |
microRNA 361 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR361 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr X:78,246,206...78,246,275
Ensembl chr X:78,246,206...78,246,275
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Mir365b |
microRNA 365b |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR365B mRNA |
CTD |
PMID:25933445 |
|
NCBI chr10:64,686,255...64,686,340
Ensembl chr10:64,686,252...64,686,351
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Mir374b |
microRNA 374b |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR374B mRNA |
CTD |
PMID:25933445 |
|
NCBI chr X:68,591,732...68,591,799
Ensembl chr X:68,591,732...68,591,799
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Mir375 |
microRNA 375 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR375 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 9:76,457,911...76,457,985
Ensembl chr 9:76,457,911...76,457,985
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Mir378 |
microRNA 378 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR378 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr18:54,858,559...54,858,623
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Mir409 |
microRNA 409 |
affects expression |
EXP |
Bleomycin affects the expression of MIR409 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 6:128,757,780...128,757,856
Ensembl chr 6:128,757,779...128,757,858
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Mir423 |
microRNA 423 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR423 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr10:61,914,142...61,914,220
Ensembl chr10:61,914,133...61,914,226
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Mir425 |
microRNA 425 |
affects expression |
EXP |
Bleomycin affects the expression of MIR425 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 8:109,264,555...109,264,637
Ensembl chr 8:109,264,555...109,264,637
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Mir429 |
microRNA 429 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR429 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 5:166,647,459...166,647,543
Ensembl chr 5:166,647,459...166,647,543
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Mir449a |
microRNA 449a |
affects expression |
EXP |
Bleomycin affects the expression of MIR449A mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 2:44,670,714...44,670,804
Ensembl chr 2:44,670,714...44,670,804
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Mir450a1 |
microRNA 450a-1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR450A1 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr X:132,801,380...132,801,470
Ensembl chr X:132,801,380...132,801,470
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Mir451a |
microRNA 451a |
decreases expression |
EXP ISO |
Bleomycin results in decreased expression of MIR451A mRNA Bleomycin results in decreased expression of MIR451A protein |
CTD |
PMID:25933445 PMID:34460027 |
|
NCBI chr10:62,961,520...62,961,591
Ensembl chr10:62,961,520...62,961,591
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Mir494 |
microRNA 494 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR494 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793
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Mir497 |
microRNA 497 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR497 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr10:54,951,514...54,951,582
Ensembl chr10:54,951,505...54,951,584
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Mir500 |
microRNA 500 |
affects expression |
EXP |
Bleomycin affects the expression of MIR500 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr X:15,258,778...15,258,857
Ensembl chr X:15,258,768...15,258,859
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Mir503 |
microRNA 503 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR503 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr X:132,806,303...132,806,373
Ensembl chr X:132,806,303...132,806,373
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Mir532 |
microRNA 532 |
affects expression |
EXP |
Bleomycin affects the expression of MIR532 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr X:15,247,315...15,247,393
Ensembl chr X:15,247,315...15,247,393
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Mir542 |
microRNA 542 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR542 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr X:132,802,623...132,802,701
Ensembl chr X:132,802,623...132,802,701
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Mir6215 |
microRNA 6215 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR6215 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 5:151,850,759...151,850,825
Ensembl chr 5:151,850,759...151,850,825
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Mir6216 |
microRNA 6216 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR6216 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 3:44,756,861...44,756,938
Ensembl chr 3:44,756,861...44,756,938
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Mir6328 |
microRNA 6328 |
affects expression |
EXP |
Bleomycin affects the expression of MIR6328 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr20:2,885,300...2,885,396
Ensembl chr20:2,885,300...2,885,396
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Mir652 |
microRNA 652 |
affects expression |
EXP |
Bleomycin affects the expression of MIR652 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr X:106,343,293...106,343,373
Ensembl chr X:106,343,293...106,343,373
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Mir93 |
microRNA 93 |
affects expression |
EXP |
Bleomycin affects the expression of MIR93 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr12:17,043,135...17,043,221
Ensembl chr12:17,043,135...17,043,221
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Mir96 |
microRNA 96 |
affects expression |
EXP |
Bleomycin affects the expression of MIR96 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 4:58,788,411...58,788,516
Ensembl chr 4:58,788,411...58,788,516
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Mir98 |
microRNA 98 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR98 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr X:20,981,235...20,981,342
Ensembl chr X:20,981,235...20,981,342
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Mir99a |
microRNA 99a |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR99A mRNA |
CTD |
PMID:25933445 |
|
NCBI chr11:16,200,443...16,200,523
Ensembl chr11:16,200,443...16,200,523
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G |
Mir99b |
microRNA 99b |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR99B mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 1:58,677,015...58,677,084
Ensembl chr 1:58,677,011...58,677,090
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G |
Mirlet7b |
microRNA let-7b |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIRLET7B mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 7:116,804,186...116,804,270
Ensembl chr 7:116,804,186...116,804,270
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G |
Mirlet7d |
microRNA let-7d |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIRLET7D mRNA |
CTD |
PMID:25933445 |
|
NCBI chr17:16,115,893...16,115,990
Ensembl chr17:16,115,893...16,115,990
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G |
Mirlet7i |
microRNA let-7i |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIRLET7I mRNA |
CTD |
PMID:25933445 |
|
NCBI chr 7:58,642,485...58,642,569
Ensembl chr 7:58,642,480...58,642,571
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Mmp1 |
matrix metallopeptidase 1 |
increases expression |
ISO |
Bleomycin results in increased expression of MMP1 mRNA; Bleomycin results in increased expression of MMP1 protein |
CTD |
PMID:18684396 |
|
NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
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G |
Mmp2 |
matrix metallopeptidase 2 |
multiple interactions increases expression |
EXP ISO |
allyl sulfide inhibits the reaction [Bleomycin results in increased expression of MMP2 protein]; celastrol inhibits the reaction [Bleomycin results in increased expression of MMP2 protein] Bleomycin results in increased expression of and results in increased secretion of MMP2 protein; Curcumin inhibits the reaction [Bleomycin results in increased expression of and results in increased secretion of MMP2 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of MMP2 mRNA] Bleomycin results in increased expression of MMP2 mRNA; Bleomycin results in increased expression of MMP2 protein |
CTD |
PMID:23656969 PMID:26345256 PMID:26768587 PMID:29175452 PMID:35716765 |
|
NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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Mmp23 |
matrix metallopeptidase 23 |
increases expression |
ISO |
Bleomycin results in increased expression of MMP23 mRNA |
CTD |
PMID:36087614 |
|
NCBI chr 5:166,239,643...166,242,734
Ensembl chr 5:166,239,644...166,242,433
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Mmp3 |
matrix metallopeptidase 3 |
multiple interactions increases expression |
ISO |
[MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; Dinoprostone inhibits the reaction [Bleomycin results in increased expression of MMP3 mRNA]; MMP3 protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]] 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Bleomycin results in increased expression of MMP3 mRNA]; Apigenin inhibits the reaction [Bleomycin results in increased expression of MMP3 mRNA] |
CTD |
PMID:28434932 PMID:32554301 |
|
NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
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Mmp7 |
matrix metallopeptidase 7 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of MMP7 protein honokiol inhibits the reaction [Bleomycin results in increased expression of MMP7 protein] |
CTD |
PMID:32032644 |
|
NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
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Mmp9 |
matrix metallopeptidase 9 |
increases expression multiple interactions |
EXP ISO |
Bleomycin results in increased expression of MMP9 protein 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of MMP9 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]; Bleomycin results in increased expression of and results in increased secretion of MMP9 protein; Curcumin inhibits the reaction [Bleomycin results in increased expression of and results in increased secretion of MMP9 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of MMP9 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of MMP9 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]; NOS2 protein affects the reaction [Bleomycin results in increased expression of MMP9 protein] Bleomycin results in increased expression of MMP9 mRNA; Bleomycin results in increased expression of MMP9 protein allyl sulfide inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]; celastrol inhibits the reaction [Bleomycin results in increased expression of MMP9 protein] |
CTD |
PMID:23656969 PMID:26526764 PMID:26768587 PMID:28300665 PMID:28694203 PMID:35716765 More...
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NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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Mpo |
myeloperoxidase |
multiple interactions increases expression increases activity |
ISO EXP |
Oils, Volatile inhibits the reaction [Bleomycin results in increased activity of MPO protein]; pirinixic acid inhibits the reaction [Bleomycin results in increased activity of MPO protein]; verlukast inhibits the reaction [Bleomycin results in increased activity of MPO protein]; zileuton inhibits the reaction [Bleomycin results in increased activity of MPO protein] Bleomycin results in increased expression of MPO protein Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of MPO protein]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of MPO protein]; resveratrol inhibits the reaction [Bleomycin results in increased activity of MPO protein] |
CTD |
PMID:16317386 PMID:17035056 PMID:17118201 PMID:26093215 PMID:28850077 |
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NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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G |
Mrc1 |
mannose receptor, C type 1 |
increases expression |
ISO |
Bleomycin results in increased expression of MRC1 mRNA |
CTD |
PMID:29033951 |
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NCBI chr17:77,249,187...77,330,857
Ensembl chr17:77,249,187...77,330,857
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G |
Msn |
moesin |
decreases expression |
EXP |
Bleomycin results in decreased expression of MSN protein |
CTD |
PMID:25933445 |
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NCBI chr X:60,996,043...61,064,011
Ensembl chr X:60,995,951...61,065,628
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G |
Muc5ac |
mucin 5AC, oligomeric mucus/gel-forming |
increases expression multiple interactions |
ISO EXP |
Bleomycin results in increased expression of MUC5AC mRNA Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of MUC5AC mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of MUC5AC mRNA] |
CTD |
PMID:18684396 PMID:26093215 |
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NCBI chr 1:196,864,336...196,896,475
Ensembl chr 1:196,864,336...196,896,475
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G |
Mucl3 |
mucin like 3 |
increases expression |
ISO |
Bleomycin results in increased expression of MUCL3 mRNA |
CTD |
PMID:36087614 |
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NCBI chr20:3,100,652...3,108,569
Ensembl chr20:3,100,679...3,108,569
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G |
Mug2 |
murinoglobulin 2 |
increases expression |
EXP |
Bleomycin results in increased expression of PZP protein |
CTD |
PMID:25933445 |
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NCBI chr 4:155,164,061...155,236,894
Ensembl chr 4:155,164,011...155,236,475
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G |
Mxi1 |
MAX interactor 1, dimerization protein |
decreases expression |
ISO |
Bleomycin results in decreased expression of MXI1 mRNA |
CTD |
PMID:33770205 |
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NCBI chr 1:252,323,915...252,383,682
Ensembl chr 1:252,323,303...252,383,681
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G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
increases response to substance |
ISO |
MYC protein results in increased susceptibility to Bleomycin |
CTD |
PMID:10449034 |
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NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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G |
Myh11 |
myosin heavy chain 11 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MYH11 protein |
CTD |
PMID:25933445 |
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NCBI chr10:743,364...838,459
Ensembl chr10:743,685...838,459
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G |
Myh6 |
myosin heavy chain 6 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MYH6 protein |
CTD |
PMID:25933445 |
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NCBI chr15:28,418,120...28,442,316
Ensembl chr15:28,417,616...28,441,720
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G |
Myl12b |
myosin light chain 12B |
increases expression |
EXP |
Bleomycin results in increased expression of MYL12B protein |
CTD |
PMID:25933445 |
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NCBI chr 9:110,873,855...110,888,187
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G |
Myl4 |
myosin, light chain 4 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MYL4 protein |
CTD |
PMID:25933445 |
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NCBI chr10:89,449,456...89,485,365
Ensembl chr10:89,449,443...89,485,363
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G |
Myl6 |
myosin light chain 6 |
increases expression |
EXP |
Bleomycin results in increased expression of MYL6 protein |
CTD |
PMID:25933445 |
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NCBI chr 7:910,764...914,062
Ensembl chr 7:910,774...933,791
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G |
Myo1c |
myosin 1C |
decreases expression |
EXP |
Bleomycin results in decreased expression of MYO1C protein |
CTD |
PMID:25933445 |
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NCBI chr10:60,498,372...60,520,752
Ensembl chr10:60,498,280...60,520,752
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G |
Myo1e |
myosin IE |
decreases expression |
ISO |
Bleomycin results in decreased expression of MYO1E mRNA |
CTD |
PMID:33770205 |
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NCBI chr 8:70,887,934...71,080,180
Ensembl chr 8:70,887,870...71,080,169
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G |
Nap1l1 |
nucleosome assembly protein 1-like 1 |
decreases expression |
ISO |
Bleomycin results in decreased expression of NAP1L1 protein |
CTD |
PMID:29733421 |
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NCBI chr 7:46,933,278...46,957,853
Ensembl chr 7:46,933,356...46,956,593
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G |
Nfatc2 |
nuclear factor of activated T-cells 2 |
multiple interactions increases expression |
ISO |
MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of NFATC2 mRNA] |
CTD |
PMID:28726637 |
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NCBI chr 3:157,195,970...157,328,640
Ensembl chr 3:157,198,872...157,328,325
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
affects localization multiple interactions decreases expression increases expression increases phosphorylation |
ISO EXP |
Bleomycin affects the localization of NFE2L2 protein Ephedrine inhibits the reaction [Bleomycin results in decreased expression of NFE2L2 protein] Berberine promotes the reaction [Bleomycin results in increased expression of NFE2L2 protein]; celastrol inhibits the reaction [Bleomycin results in decreased expression of NFE2L2 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in decreased expression of NFE2L2 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in decreased expression of NFE2L2 mRNA] Bleomycin results in decreased expression of NFE2L2 mRNA; Bleomycin results in decreased expression of NFE2L2 protein caffeic acid phenethyl ester inhibits the reaction [Bleomycin results in decreased expression of NFE2L2 protein]; U 0126 inhibits the reaction [Bleomycin affects the localization of NFE2L2 protein]; U 0126 inhibits the reaction [Bleomycin results in increased phosphorylation of NFE2L2 protein] |
CTD |
PMID:23523906 PMID:23570914 PMID:26093215 PMID:26768587 PMID:37778983 |
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NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
increases activity multiple interactions increases expression |
ISO EXP |
Bleomycin results in increased activity of NFKB1 protein NOS2 protein affects the reaction [Bleomycin results in increased activity of NFKB1 protein] Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of NFKB1 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of NFKB1 mRNA] |
CTD |
PMID:12003776 PMID:26093215 PMID:26526764 |
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NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions |
ISO |
[Bleomycin results in increased phosphorylation of GSK3B protein] inhibits the reaction [GSK3B protein binds to and results in increased stability of NFKBIA protein] |
CTD |
PMID:19429264 |
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NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Nfkbiz |
NFKB inhibitor zeta |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of NFKBIZ mRNA 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Bleomycin results in increased expression of NFKBIZ mRNA] |
CTD |
PMID:32554301 |
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NCBI chr11:44,782,676...44,810,722
Ensembl chr11:44,782,676...44,810,723
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G |
Nherf1 |
NHERF family PDZ scaffold protein 1 |
increases expression |
EXP |
Bleomycin results in increased expression of NHERF1 protein |
CTD |
PMID:25933445 |
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NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598
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G |
Nherf2 |
NHERF family PDZ scaffold protein 2 |
decreases expression |
EXP |
Bleomycin results in decreased expression of NHERF2 protein |
CTD |
PMID:25933445 |
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NCBI chr10:13,662,461...13,672,975
Ensembl chr10:13,662,461...13,673,049
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G |
Nit2 |
nitrilase family, member 2 |
multiple interactions |
ISO |
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of NIT2 protein |
CTD |
PMID:29733421 |
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NCBI chr11:43,363,839...43,378,713
Ensembl chr11:43,363,985...43,375,024
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G |
Nlrp10 |
NLR family, pyrin domain containing 10 |
increases expression |
ISO |
Bleomycin results in increased expression of NLRP10 mRNA |
CTD |
PMID:36087614 |
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NCBI chr 1:162,922,806...162,930,363
Ensembl chr 1:162,922,806...162,930,363
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G |
Nmbr |
neuromedin B receptor |
decreases expression |
EXP |
Bleomycin results in decreased expression of NMBR mRNA |
CTD |
PMID:15808516 |
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NCBI chr 1:9,115,033...9,146,081
Ensembl chr 1:9,134,889...9,145,462
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G |
Nme2 |
NME/NM23 nucleoside diphosphate kinase 2 |
increases expression |
EXP |
Bleomycin results in increased expression of NME2 protein |
CTD |
PMID:25933445 |
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NCBI chr10:78,898,097...78,903,514
Ensembl chr10:78,897,770...78,903,538
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G |
Nos2 |
nitric oxide synthase 2 |
increases expression multiple interactions increases secretion |
ISO EXP |
Bleomycin results in increased expression of NOS2 protein yupingfeng inhibits the reaction [Bleomycin results in increased secretion of NOS2 protein] Berberine inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of NOS2 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of NOS2 mRNA]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; Taurine inhibits the reaction [Bleomycin results in increased expression of NOS2 protein] Bleomycin results in increased expression of NOS2 mRNA; Bleomycin results in increased expression of NOS2 protein 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; NOS2 protein affects the reaction [Bleomycin results in increased activity of NFKB1 protein]; NOS2 protein affects the reaction [Bleomycin results in increased expression of LGALS3 protein]; NOS2 protein affects the reaction [Bleomycin results in increased expression of MMP9 protein]; NOS2 protein affects the reaction [Bleomycin results in increased expression of RETNLA protein]; rosiglitazone inhibits the reaction [Bleomycin results in increased expression of NOS2 protein] |
CTD |
PMID:15684285 PMID:17434272 PMID:19362168 PMID:23523906 PMID:26526764 PMID:27704718 PMID:33647319 PMID:37898439 More...
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Notch4 |
notch receptor 4 |
increases expression |
ISO |
Bleomycin results in increased expression of NOTCH4 mRNA |
CTD |
PMID:36087614 |
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NCBI chr20:4,160,362...4,184,466
Ensembl chr20:4,160,445...4,184,465
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G |
Nox4 |
NADPH oxidase 4 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of NOX4 mRNA geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of NOX4 mRNA]; Thioctic Acid inhibits the reaction [Bleomycin results in increased expression of NOX4 mRNA] |
CTD |
PMID:35187969 PMID:37307957 |
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NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
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G |
Npm1 |
nucleophosmin 1 |
increases expression |
EXP |
Bleomycin results in increased expression of NPM1 protein |
CTD |
PMID:25933445 |
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NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
decreases activity multiple interactions |
EXP |
Bleomycin results in decreased activity of NQO1 protein celastrol inhibits the reaction [Bleomycin results in decreased activity of NQO1 protein] |
CTD |
PMID:26768587 |
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NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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G |
Nr3c1 |
nuclear receptor subfamily 3, group C, member 1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of NR3C1 mRNA |
CTD |
PMID:15808516 |
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NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
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G |
Nr3c2 |
nuclear receptor subfamily 3, group C, member 2 |
decreases expression |
EXP |
Bleomycin results in decreased expression of NR3C2 mRNA |
CTD |
PMID:15808516 |
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NCBI chr19:30,715,634...31,059,885
Ensembl chr19:30,715,648...31,059,885
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G |
Nucb2 |
nucleobindin 2 |
increases expression |
EXP |
Bleomycin results in increased expression of NUCB2 protein |
CTD |
PMID:25933445 |
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NCBI chr 1:170,750,830...170,787,356
Ensembl chr 1:170,750,877...170,787,353
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G |
Oat |
ornithine aminotransferase |
multiple interactions |
ISO |
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of OAT protein |
CTD |
PMID:29733421 |
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NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
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G |
Ogg1 |
8-oxoguanine DNA glycosylase |
increases expression multiple interactions affects response to substance |
ISO |
Bleomycin results in increased expression of OGG1 protein OGG1 protein affects the reaction [Bleomycin results in decreased expression of CDH1 protein]; OGG1 protein affects the reaction [Bleomycin results in increased expression of CCN2 protein]; OGG1 protein affects the reaction [Bleomycin results in increased expression of CDH2 protein]; OGG1 protein affects the reaction [Bleomycin results in increased expression of FN1 protein]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in increased expression of CDH2 protein]]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in increased expression of FN1 protein]]; OGG1 protein promotes the reaction [Bleomycin results in increased expression of CCN2 protein]; OGG1 protein promotes the reaction [Bleomycin results in increased expression of FN1 protein]; pirfenidone inhibits the reaction [Bleomycin results in increased expression of OGG1 protein]; TH5487 inhibits the reaction [Bleomycin results in increased expression of OGG1 protein] OGG1 protein affects the susceptibility to Bleomycin |
CTD |
PMID:35654123 |
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NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
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G |
Osr1 |
odd-skipped related transcription factor 1 |
increases expression |
ISO |
Bleomycin results in increased expression of OSR1 protein |
CTD |
PMID:34460027 |
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NCBI chr 6:32,369,561...32,380,822
Ensembl chr 6:32,373,816...32,380,817
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G |
Ostf1 |
osteoclast stimulating factor 1 |
increases expression |
EXP |
Bleomycin results in increased expression of OSTF1 protein |
CTD |
PMID:25933445 |
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NCBI chr 1:216,002,037...216,049,226
Ensembl chr 1:216,002,044...216,049,221
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G |
P4hb |
prolyl 4-hydroxylase subunit beta |
increases expression |
EXP |
Bleomycin results in increased expression of P4HB protein |
CTD |
PMID:25933445 |
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NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500
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G |
Pabpc1 |
poly(A) binding protein, cytoplasmic 1 |
increases expression |
EXP |
Bleomycin results in increased expression of PABPC1 protein |
CTD |
PMID:25933445 |
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NCBI chr 7:67,777,438...67,789,731
Ensembl chr 7:67,777,381...67,789,744
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
increases expression multiple interactions increases cleavage |
ISO EXP |
Bleomycin results in increased expression of PARP1 protein Bleomycin inhibits the reaction [Azacitidine results in increased cleavage of PARP1 protein] Bleomycin results in increased cleavage of PARP1 protein |
CTD |
PMID:15371238 PMID:16317386 PMID:32278510 |
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NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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G |
Pcbp2 |
poly(rC) binding protein 2 |
multiple interactions |
ISO |
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of PCBP2 protein |
CTD |
PMID:29733421 |
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NCBI chr 7:133,605,375...133,631,312
Ensembl chr 7:133,605,573...133,629,863
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G |
Pdia3 |
protein disulfide isomerase family A, member 3 |
multiple interactions |
EXP |
[Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of PDIA3 protein |
CTD |
PMID:24478030 |
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NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
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G |
Pdlim1 |
PDZ and LIM domain 1 |
increases expression |
EXP |
Bleomycin results in increased expression of PDLIM1 protein |
CTD |
PMID:25933445 |
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NCBI chr 1:239,042,372...239,091,074
Ensembl chr 1:239,042,385...239,091,076
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G |
Pdlim5 |
PDZ and LIM domain 5 |
increases expression |
EXP |
Bleomycin results in increased expression of PDLIM5 protein |
CTD |
PMID:25933445 |
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NCBI chr 2:230,952,251...231,120,329
Ensembl chr 2:230,952,248...231,120,275
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G |
Pdxk |
pyridoxal kinase |
increases expression |
EXP |
Bleomycin results in increased expression of PDXK protein |
CTD |
PMID:25933445 |
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NCBI chr20:10,210,276...10,232,314
Ensembl chr20:10,210,289...10,232,110
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G |
Pecam1 |
platelet and endothelial cell adhesion molecule 1 |
multiple interactions decreases expression |
ISO |
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of PECAM1 protein] |
CTD |
PMID:30825431 |
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NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116
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G |
Plau |
plasminogen activator, urokinase |
increases expression multiple interactions decreases expression |
ISO |
Bleomycin results in increased expression of PLAU mRNA; Bleomycin results in increased expression of PLAU protein Curcumin inhibits the reaction [Bleomycin results in decreased expression of PLAU mRNA]; Curcumin inhibits the reaction [Bleomycin results in decreased expression of PLAU protein] Bleomycin results in decreased expression of PLAU mRNA; Bleomycin results in decreased expression of PLAU protein |
CTD |
PMID:25648892 PMID:35716765 |
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NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
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G |
Plaur |
plasminogen activator, urokinase receptor |
decreases expression multiple interactions |
ISO |
Bleomycin results in decreased expression of PLAUR mRNA; Bleomycin results in decreased expression of PLAUR protein Curcumin inhibits the reaction [Bleomycin results in decreased expression of PLAUR mRNA]; Curcumin inhibits the reaction [Bleomycin results in decreased expression of PLAUR protein] |
CTD |
PMID:35716765 |
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NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595
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G |
Pml |
PML nuclear body scaffold |
multiple interactions increases expression |
ISO |
arsenic trioxide inhibits the reaction [Bleomycin results in increased expression of PML protein] |
CTD |
PMID:24762191 |
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NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
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G |
Pnp |
purine nucleoside phosphorylase |
decreases expression |
EXP |
Bleomycin results in decreased expression of PNP protein |
CTD |
PMID:25933445 |
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NCBI chr15:24,170,607...24,178,269
Ensembl chr15:24,170,602...24,203,986
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G |
Podxl |
podocalyxin-like |
decreases expression |
EXP |
Bleomycin results in decreased expression of PODXL protein |
CTD |
PMID:25933445 |
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NCBI chr 4:60,135,124...60,181,829
Ensembl chr 4:60,135,109...60,181,899
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G |
Polb |
DNA polymerase beta |
decreases response to substance |
ISO |
POLB results in decreased susceptibility to Bleomycin |
CTD |
PMID:21251944 |
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NCBI chr16:69,379,438...69,402,710
Ensembl chr16:69,379,400...69,404,812
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions decreases response to substance |
ISO |
PPARA protein affects the reaction [Bleomycin results in increased expression of HMOX1 protein]; PPARA protein affects the reaction [Bleomycin results in increased expression of IL1B protein]; PPARA protein affects the reaction [Bleomycin results in increased expression of TNF protein] PPARA protein results in decreased susceptibility to Bleomycin |
CTD |
PMID:16317386 |
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NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
decreases expression multiple interactions |
ISO |
Bleomycin results in decreased expression of PPARG mRNA; Bleomycin results in decreased expression of PPARG protein Berberine inhibits the reaction [Bleomycin binds to PPARG protein] lenabasum inhibits the reaction [Bleomycin results in decreased expression of PPARG protein]; Rosiglitazone inhibits the reaction [Bleomycin results in decreased expression of PPARG mRNA] |
CTD |
PMID:19147827 PMID:27153807 PMID:29408570 |
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ppfia4 |
PTPRF interacting protein alpha 4 |
multiple interactions increases expression |
ISO |
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of PPFIA4 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of PPFIA4 mRNA] |
CTD |
PMID:30825431 |
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NCBI chr13:45,753,827...45,802,305
Ensembl chr13:45,753,827...45,802,261
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Ppia |
peptidylprolyl isomerase A |
increases expression |
EXP |
Bleomycin results in increased expression of PPIA protein |
CTD |
PMID:25933445 |
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NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
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Prdx2 |
peroxiredoxin 2 |
decreases expression |
EXP |
Bleomycin results in decreased expression of PRDX2 protein |
CTD |
PMID:25933445 |
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NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194
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Prdx6 |
peroxiredoxin 6 |
decreases expression |
EXP |
Bleomycin results in decreased expression of PRDX6 protein |
CTD |
PMID:25933445 |
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NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355
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Prelp |
proline and arginine rich end leucine rich repeat protein |
decreases expression |
EXP |
Bleomycin results in decreased expression of PRELP protein |
CTD |
PMID:25933445 |
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NCBI chr13:45,368,407...45,391,480
Ensembl chr13:45,370,533...45,380,270
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Psmd13 |
proteasome 26S subunit, non-ATPase 13 |
multiple interactions |
ISO |
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of PSMD13 protein |
CTD |
PMID:29733421 |
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NCBI chr 1:195,964,617...195,976,895
Ensembl chr 1:195,964,138...195,976,905
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Psme1 |
proteasome activator subunit 1 |
increases expression |
EXP |
Bleomycin results in increased expression of PSME1 protein |
CTD |
PMID:25933445 |
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NCBI chr15:29,069,012...29,071,888
Ensembl chr15:29,068,729...29,071,890
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Psme2 |
proteasome activator subunit 2 |
decreases expression |
EXP |
Bleomycin results in decreased expression of PSME2 protein |
CTD |
PMID:25933445 |
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NCBI chr15:29,078,495...29,082,794
Ensembl chr15:29,078,500...29,082,946
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Ptafr |
platelet-activating factor receptor |
multiple interactions increases expression |
ISO |
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of PTAFR mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of PTAFR mRNA] |
CTD |
PMID:30825431 |
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NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251
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Ptbp1 |
polypyrimidine tract binding protein 1 |
increases expression |
EXP |
Bleomycin results in increased expression of PTBP1 protein |
CTD |
PMID:25933445 |
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NCBI chr 7:9,842,574...9,852,332
Ensembl chr 7:9,842,574...9,852,397
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Pten |
phosphatase and tensin homolog |
multiple interactions decreases expression |
ISO |
((3Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-((4-methylpiperazin-1-yl)carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide) inhibits the reaction [Berberine inhibits the reaction [Bleomycin results in decreased expression of PTEN mRNA]]; Berberine inhibits the reaction [Bleomycin results in decreased expression of PTEN mRNA]; Berberine inhibits the reaction [Bleomycin results in decreased expression of PTEN protein] Bleomycin results in decreased expression of PTEN mRNA; Bleomycin results in decreased expression of PTEN protein |
CTD |
PMID:29408570 |
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NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
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Ptgdr |
prostaglandin D2 receptor |
increases expression |
ISO |
Bleomycin results in increased expression of PTGDR mRNA |
CTD |
PMID:20719937 |
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NCBI chr15:17,360,304...17,367,679
Ensembl chr15:17,360,304...17,367,679
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Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of PTGS2 mRNA; Bleomycin results in increased expression of PTGS2 protein 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of PTGS2 protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Bleomycin results in increased expression of PTGS2 mRNA] |
CTD |
PMID:26526764 PMID:27704718 PMID:32828905 |
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NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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Ptms |
parathymosin |
increases expression |
EXP |
Bleomycin results in increased expression of PTMS protein |
CTD |
PMID:25933445 |
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NCBI chr 4:157,722,384...157,726,575
Ensembl chr 4:157,722,386...157,727,009
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Rab1b |
RAB1B, member RAS oncogene family |
increases expression |
EXP |
Bleomycin results in increased expression of RAB1B protein |
CTD |
PMID:25933445 |
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NCBI chr 1:202,405,759...202,413,850
Ensembl chr 1:202,405,759...202,413,868 Ensembl chr X:202,405,759...202,413,868
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Rac2 |
Rac family small GTPase 2 |
multiple interactions increases expression |
ISO |
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of RAC2 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of RAC2 mRNA] |
CTD |
PMID:30825431 |
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NCBI chr 7:110,101,344...110,128,718
Ensembl chr 7:110,116,260...110,128,720
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Rad51ap1 |
RAD51 associated protein 1 |
decreases expression multiple interactions |
ISO |
Bleomycin results in decreased expression of RAD51AP1 mRNA Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of RAD51AP1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of RAD51AP1 mRNA] |
CTD |
PMID:30825431 |
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NCBI chr 4:159,759,454...159,772,473
Ensembl chr 4:159,759,459...159,772,524
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Ralb |
RAS like proto-oncogene B |
increases expression |
EXP |
Bleomycin results in increased expression of RALB protein |
CTD |
PMID:25933445 |
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NCBI chr13:30,588,036...30,624,199
Ensembl chr13:30,588,033...30,624,202
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Rap1b |
RAP1B, member of RAS oncogene family |
increases expression |
EXP |
Bleomycin results in increased expression of RAP1B protein |
CTD |
PMID:25933445 |
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NCBI chr 7:53,423,039...53,456,349
Ensembl chr 7:53,423,130...53,456,370
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Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions increases phosphorylation decreases expression increases expression |
ISO EXP |
Calcitriol inhibits the reaction [Bleomycin results in increased expression of RELA protein]; geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of RELA mRNA]; honokiol inhibits the reaction [Bleomycin results in increased expression of RELA protein modified form]; methyl palmitate inhibits the reaction [Bleomycin results in increased expression of RELA protein] Ephedrine inhibits the reaction [Bleomycin results in increased phosphorylation of RELA protein] Bleomycin results in decreased expression of RELA mRNA Bleomycin results in increased expression of RELA mRNA; Bleomycin results in increased expression of RELA protein; Bleomycin results in increased expression of RELA protein modified form Berberine inhibits the reaction [Bleomycin affects the localization of and results in increased expression of RELA protein]; Bleomycin affects the localization of and results in increased expression of RELA protein; thymoquinone inhibits the reaction [Bleomycin results in increased expression of RELA protein] |
CTD |
PMID:21575650 PMID:22982510 PMID:23523906 PMID:26520185 PMID:29720568 PMID:32032644 PMID:37307957 PMID:37778983 More...
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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Relb |
RELB proto-oncogene, NF-kB subunit |
decreases expression |
ISO |
Bleomycin results in decreased expression of RELB mRNA |
CTD |
PMID:29720568 |
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NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507
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G |
Robo1 |
roundabout guidance receptor 1 |
decreases expression multiple interactions |
ISO |
Bleomycin results in decreased expression of ROBO1 mRNA Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of ROBO1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of ROBO1 mRNA] |
CTD |
PMID:30825431 |
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NCBI chr11:10,580,863...11,621,675
Ensembl chr11:10,580,908...11,620,203
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G |
Rpl12 |
ribosomal protein L12 |
increases expression |
EXP |
Bleomycin results in increased expression of RPL12 protein |
CTD |
PMID:25933445 |
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NCBI chr 3:16,264,269...16,266,645
Ensembl chr 3:16,264,251...16,266,642
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G |
Rpl13 |
ribosomal protein L13 |
increases expression |
EXP |
Bleomycin results in increased expression of RPL13 protein |
CTD |
PMID:25933445 |
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NCBI chr19:51,153,990...51,156,541
Ensembl chr19:51,153,924...51,163,014
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Rpl4 |
ribosomal protein L4 |
increases expression |
EXP |
Bleomycin results in increased expression of RPL4 protein |
CTD |
PMID:25933445 |
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NCBI chr 8:64,671,177...64,676,301
Ensembl chr 8:64,671,160...64,676,306
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Rpl5 |
ribosomal protein L5 |
increases expression |
EXP |
Bleomycin results in increased expression of RPL5 protein |
CTD |
PMID:25933445 |
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NCBI chr14:1,843,856...1,850,301
Ensembl chr14:1,843,770...1,850,290
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Rpl6 |
ribosomal protein L6 |
affects expression |
EXP |
Bleomycin affects the expression of RPL6 protein |
CTD |
PMID:25933445 |
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NCBI chr12:35,347,493...35,352,011
Ensembl chr12:35,347,497...35,351,921
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Rps3a |
ribosomal protein S3a |
increases expression |
EXP |
Bleomycin results in increased expression of RPS3A1 protein |
CTD |
PMID:25933445 |
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NCBI chr 2:171,524,685...171,529,054
Ensembl chr 2:171,524,500...171,529,055
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S100a11 |
S100 calcium binding protein A11 |
increases expression |
EXP |
Bleomycin results in increased expression of S100A11 protein |
CTD |
PMID:25933445 |
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NCBI chr 2:179,191,688...179,197,098
Ensembl chr 2:179,191,715...179,197,044
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S100a4 |
S100 calcium-binding protein A4 |
increases expression multiple interactions |
EXP |
Bleomycin results in increased expression of S100A4 protein andrographolide inhibits the reaction [Bleomycin results in increased expression of S100A4 protein] |
CTD |
PMID:25933445 PMID:31706003 |
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NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254
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G |
S100a6 |
S100 calcium binding protein A6 |
affects expression |
EXP |
Bleomycin affects the expression of S100A6 protein |
CTD |
PMID:25933445 |
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NCBI chr 2:176,100,619...176,102,181
Ensembl chr 2:176,100,899...176,102,180
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S100a8 |
S100 calcium binding protein A8 |
increases expression |
EXP |
Bleomycin results in increased expression of S100A8 protein |
CTD |
PMID:25933445 |
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NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
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G |
S1pr1 |
sphingosine-1-phosphate receptor 1 |
multiple interactions |
ISO |
[S1PR5 protein affects the susceptibility to Bleomycin] which affects the expression of S1PR1 protein |
CTD |
PMID:29033951 |
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NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681
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S1pr3 |
sphingosine-1-phosphate receptor 3 |
multiple interactions increases expression |
ISO |
S1PR5 protein affects the reaction [Bleomycin results in increased expression of S1PR3 mRNA] |
CTD |
PMID:29033951 |
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NCBI chr17:13,781,050...13,794,408
Ensembl chr17:13,781,050...13,794,505
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G |
S1pr5 |
sphingosine-1-phosphate receptor 5 |
multiple interactions affects response to substance |
ISO |
[S1PR5 protein affects the susceptibility to Bleomycin] which affects the expression of COMP protein; [S1PR5 protein affects the susceptibility to Bleomycin] which affects the expression of S1PR1 protein; S1PR5 protein affects the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; S1PR5 protein affects the reaction [Bleomycin results in increased expression of GATA3 mRNA]; S1PR5 protein affects the reaction [Bleomycin results in increased expression of S1PR3 mRNA]; S1PR5 protein affects the reaction [Bleomycin results in increased expression of SMAD7 mRNA] |
CTD |
PMID:29033951 |
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NCBI chr 8:19,786,676...19,791,862
Ensembl chr 8:19,786,663...19,791,795
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Scarna15 |
small Cajal body-specific RNA 15 |
affects expression |
EXP |
Bleomycin affects the expression of SCARNA15 mRNA |
CTD |
PMID:25933445 |
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NCBI chr 1:135,484,620...135,484,683
Ensembl chr 1:135,484,559...135,484,685 Ensembl chr 1:135,484,559...135,484,685
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Scgb1a1 |
secretoglobin family 1A member 1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of SCGB1A1 protein |
CTD |
PMID:25933445 |
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NCBI chr 1:205,977,060...205,980,610
Ensembl chr 1:205,977,060...205,980,610
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Scp2 |
sterol carrier protein 2 |
increases expression |
EXP |
Bleomycin results in increased expression of SCP2 protein |
CTD |
PMID:25933445 |
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NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287
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Scpep1 |
serine carboxypeptidase 1 |
increases expression |
EXP |
Bleomycin results in increased expression of SCPEP1 protein |
CTD |
PMID:25933445 |
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NCBI chr10:73,703,275...73,732,892
Ensembl chr10:73,703,278...73,732,850
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G |
Scube3 |
signal peptide, CUB domain and EGF like domain containing 3 |
multiple interactions decreases expression |
ISO |
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of SCUBE3 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of SCUBE3 mRNA] |
CTD |
PMID:30825431 |
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NCBI chr20:6,199,182...6,231,100
Ensembl chr20:6,199,182...6,228,584
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G |
Sec14l3 |
SEC14-like lipid binding 3 |
decreases expression |
EXP |
Bleomycin results in decreased expression of SEC14L3 protein |
CTD |
PMID:25933445 |
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NCBI chr14:78,944,568...78,955,608
Ensembl chr14:78,912,750...78,956,099
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Selenbp1 |
selenium binding protein 1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of SELENBP1 protein |
CTD |
PMID:25933445 |
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NCBI chr 2:182,494,004...182,504,594
Ensembl chr 2:182,493,978...182,504,594
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G |
Serpinb2 |
serpin family B member 2 |
multiple interactions increases expression |
ISO |
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of SERPINB2 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of SERPINB2 mRNA] |
CTD |
PMID:30825431 |
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NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408
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Serpine1 |
serpin family E member 1 |
increases expression multiple interactions decreases expression |
ISO |
Bleomycin results in increased expression of SERPINE1 mRNA; Bleomycin results in increased expression of SERPINE1 protein Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of SERPINE1 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of SERPINE1 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of SERPINE1 protein]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of SERPINE1 protein] |
CTD |
PMID:29175452 PMID:30825431 PMID:35716765 |
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NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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G |
Serpinh1 |
serpin family H member 1 |
multiple interactions increases expression |
EXP |
allyl sulfide inhibits the reaction [Bleomycin results in increased expression of SERPINH1 protein] |
CTD |
PMID:23656969 PMID:25933445 |
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NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801
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Sfrp1 |
secreted frizzled-related protein 1 |
increases expression |
ISO |
Bleomycin results in increased expression of SFRP1 mRNA |
CTD |
PMID:26345256 |
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NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286
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Sftpa1 |
surfactant protein A1 |
multiple interactions increases expression decreases expression |
ISO EXP |
[Bleomycin co-treated with SFTPA1 protein polymorphism] results in increased expression of CXCL8 protein; [Bleomycin co-treated with SFTPA1 protein polymorphism] results in increased expression of TNF protein; Bleomycin promotes the reaction [[SFTPA1 protein binds to SFTPA2 protein] which results in increased expression of TNF protein]; calfactant inhibits the reaction [Bleomycin promotes the reaction [[SFTPA1 protein binds to SFTPA2 protein] which results in increased expression of TNF protein]] Bleomycin results in increased expression of SFTPA1 protein Bleomycin results in decreased expression of SFTPA1 mRNA |
CTD |
PMID:14617519 PMID:15782499 PMID:25933445 |
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NCBI chr16:17,008,180...17,011,686
Ensembl chr16:17,008,180...17,011,685
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Sftpb |
surfactant protein B |
decreases expression multiple interactions |
EXP ISO |
Bleomycin results in decreased expression of SFTPB mRNA [TNF protein affects the susceptibility to Bleomycin] which affects the expression of SFTPB protein |
CTD |
PMID:15782499 PMID:33647319 |
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NCBI chr 4:104,359,303...104,368,439
Ensembl chr 4:104,359,396...104,368,436
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Sftpc |
surfactant protein C |
decreases expression |
EXP |
Bleomycin results in decreased expression of SFTPC mRNA; Bleomycin results in decreased expression of SFTPC protein |
CTD |
PMID:34425168 |
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NCBI chr15:45,596,565...45,599,615
Ensembl chr15:45,596,574...45,610,777
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Sftpd |
surfactant protein D |
increases expression multiple interactions increases metabolic processing |
EXP ISO |
Bleomycin results in increased expression of SFTPD mRNA; Bleomycin results in increased expression of SFTPD protein [TNF protein affects the susceptibility to Bleomycin] which affects the expression of SFTPD protein; Bleomycin promotes the reaction [SFTPD protein binds to SFTPD protein binds to SFTPD protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Bleomycin results in increased metabolism of SFTPD protein] |
CTD |
PMID:11880309 PMID:25933445 PMID:26526764 PMID:33647319 |
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NCBI chr16:17,046,491...17,058,968
Ensembl chr16:17,046,483...17,059,927
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Sirt1 |
sirtuin 1 |
decreases expression multiple interactions |
ISO |
Bleomycin results in decreased expression of SIRT1 mRNA; Bleomycin results in decreased expression of SIRT1 protein resveratrol inhibits the reaction [Bleomycin results in decreased expression of SIRT1 mRNA]; resveratrol inhibits the reaction [Bleomycin results in decreased expression of SIRT1 protein] |
CTD |
PMID:25707573 |
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NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
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G |
Slc12a1 |
solute carrier family 12 member 1 |
increases expression |
EXP |
Bleomycin results in increased expression of SLC12A1 mRNA |
CTD |
PMID:15808516 |
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NCBI chr 3:112,406,140...112,482,913
Ensembl chr 3:112,406,140...112,482,899
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G |
Slc1a2 |
solute carrier family 1 member 2 |
increases expression |
EXP |
Bleomycin results in increased expression of SLC1A2 mRNA |
CTD |
PMID:15808516 |
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NCBI chr 3:89,005,129...89,135,469
Ensembl chr 3:89,005,129...89,126,498
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G |
Slc25a4 |
solute carrier family 25 member 4 |
decreases expression |
EXP |
Bleomycin results in decreased expression of SLC25A4 protein |
CTD |
PMID:25933445 |
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NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733
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G |
Slc25a5 |
solute carrier family 25 member 5 |
decreases expression |
EXP |
Bleomycin results in decreased expression of SLC25A5 protein |
CTD |
PMID:25933445 |
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NCBI chr X:116,031,896...116,034,963
Ensembl chr X:116,031,803...116,034,967
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Slc6a12 |
solute carrier family 6 member 12 |
increases expression |
EXP |
Bleomycin results in increased expression of SLC6A12 mRNA |
CTD |
PMID:15808516 |
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NCBI chr 4:154,585,386...154,603,750
Ensembl chr 4:154,585,500...154,603,750
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Slc6a15 |
solute carrier family 6 member 15 |
decreases expression multiple interactions |
ISO |
Bleomycin results in decreased expression of SLC6A15 mRNA Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of SLC6A15 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of SLC6A15 mRNA] |
CTD |
PMID:30825431 |
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NCBI chr 7:38,553,055...38,607,239
Ensembl chr 7:38,553,196...38,607,239
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Slc7a1 |
solute carrier family 7 member 1 |
decreases expression multiple interactions |
ISO |
Bleomycin results in decreased expression of SLC7A1 mRNA Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of SLC7A1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of SLC7A1 mRNA] |
CTD |
PMID:30825431 |
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NCBI chr12:6,628,288...6,703,849
Ensembl chr12:6,628,007...6,703,849
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G |
Slco2a1 |
solute carrier organic anion transporter family, member 2a1 |
increases response to substance multiple interactions |
ISO |
SLCO2A1 gene mutant form results in increased susceptibility to Bleomycin [SLCO2A1 gene mutant form results in increased susceptibility to Bleomycin] which results in increased expression of TNF mRNA; SLCO2A1 gene mutant form promotes the reaction [Bleomycin results in increased expression of CCL5 mRNA]; SLCO2A1 gene mutant form promotes the reaction [Bleomycin results in increased expression of IL1B mRNA] |
CTD |
PMID:32828905 |
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NCBI chr 8:103,588,916...103,672,546
Ensembl chr 8:103,588,916...103,672,546
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G |
Slco2b1 |
solute carrier organic anion transporter family, member 2b1 |
multiple interactions |
ISO |
Bleomycin inhibits the reaction [SLCO2B1 protein results in increased uptake of Cascade Blue] |
CTD |
PMID:30863990 |
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NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353
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G |
Slpi |
secretory leukocyte peptidase inhibitor |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of SLPI mRNA; Bleomycin results in increased expression of SLPI protein Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of SLPI mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of SLPI mRNA] |
CTD |
PMID:26345256 PMID:30825431 |
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NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453
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G |
Smad2 |
SMAD family member 2 |
increases phosphorylation increases expression multiple interactions |
ISO |
Bleomycin results in increased phosphorylation of SMAD2 protein Bleomycin results in increased expression of SMAD2 mRNA yupingfeng inhibits the reaction [Bleomycin results in increased expression of SMAD2 mRNA]; yupingfeng inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD2 protein] camostat inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD2 protein]; honokiol inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD2 protein]; Thioctic Acid inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD2 protein] |
CTD |
PMID:26599507 PMID:32032644 PMID:35187969 PMID:37898439 |
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NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
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G |
Smad3 |
SMAD family member 3 |
multiple interactions increases phosphorylation increases expression |
EXP ISO |
Phytochemicals inhibits the reaction [Bleomycin results in increased expression of SMAD3 mRNA] Bleomycin results in increased phosphorylation of SMAD3 protein 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD3 protein]; honokiol inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD3 protein]; Thioctic Acid inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD3 protein] |
CTD |
PMID:26093215 PMID:27704718 PMID:32032644 PMID:35187969 |
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NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
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G |
Smad7 |
SMAD family member 7 |
decreases expression multiple interactions increases expression |
EXP ISO |
Bleomycin results in decreased expression of SMAD7 mRNA S1PR5 protein affects the reaction [Bleomycin results in increased expression of SMAD7 mRNA] |
CTD |
PMID:26093215 PMID:29033951 |
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NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
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G |
Smc1a |
structural maintenance of chromosomes 1A |
increases phosphorylation |
ISO |
Bleomycin results in increased phosphorylation of SMC1A protein |
CTD |
PMID:24933654 |
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NCBI chr X:21,103,323...21,148,053
Ensembl chr X:21,103,282...21,148,056
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G |
Smim14 |
small integral membrane protein 14 |
decreases expression |
ISO |
Bleomycin results in decreased expression of SMIM14 mRNA |
CTD |
PMID:33770205 |
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NCBI chr14:42,783,361...42,829,762
Ensembl chr14:42,783,332...42,829,760
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G |
Smtn |
smoothelin |
decreases expression multiple interactions |
ISO |
Bleomycin results in decreased expression of SMTN mRNA Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of SMTN mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of SMTN mRNA] |
CTD |
PMID:30825431 |
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NCBI chr14:78,398,595...78,420,908
Ensembl chr14:78,397,778...78,420,886
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G |
Snora58 |
small nucleolar RNA, H/ACA box 58 |
decreases expression |
EXP |
Bleomycin results in decreased expression of SNORA58 mRNA |
CTD |
PMID:25933445 |
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NCBI chr 6:107,080,945...107,081,020
Ensembl chr 6:107,080,945...107,081,020
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G |
Socs1 |
suppressor of cytokine signaling 1 |
decreases expression |
ISO |
Bleomycin results in decreased expression of SOCS1 mRNA |
CTD |
PMID:17374387 |
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NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
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G |
Sod1 |
superoxide dismutase 1 |
increases expression decreases activity decreases expression multiple interactions |
ISO EXP |
Bleomycin results in increased expression of SOD1 protein Bleomycin results in decreased activity of SOD1 protein Bleomycin results in decreased expression of SOD1 protein IL1A protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein] |
CTD |
PMID:8317554 PMID:25933445 PMID:30106319 |
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NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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G |
Sod2 |
superoxide dismutase 2 |
increases expression multiple interactions decreases activity |
ISO EXP |
Bleomycin results in increased expression of SOD2 protein celastrol inhibits the reaction [Bleomycin results in decreased activity of SOD2 protein] IL1A protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein] |
CTD |
PMID:8317554 PMID:26768587 |
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NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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G |
Sparc |
secreted protein acidic and cysteine rich |
increases response to substance |
ISO |
SPARC protein results in increased susceptibility to Bleomycin |
CTD |
PMID:19446018 |
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NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396
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G |
Sparcl1 |
SPARC like 1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of SPARCL1 protein |
CTD |
PMID:25933445 |
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NCBI chr14:5,632,816...5,663,866
Ensembl chr14:5,632,569...5,663,865
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G |
Spc25 |
SPC25 component of NDC80 kinetochore complex |
increases expression |
ISO |
Bleomycin results in increased expression of SPC25 mRNA |
CTD |
PMID:36087614 |
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NCBI chr 3:53,930,013...53,988,940
Ensembl chr 3:53,975,704...53,988,959
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G |
Spp1 |
secreted phosphoprotein 1 |
increases expression |
ISO |
Bleomycin results in increased expression of SPP1 mRNA; Bleomycin results in increased expression of SPP1 protein |
CTD |
PMID:26345256 PMID:29175452 |
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NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
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G |
Sptan1 |
spectrin, alpha, non-erythrocytic 1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of SPTAN1 protein |
CTD |
PMID:25933445 |
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NCBI chr 3:13,241,164...13,306,047
Ensembl chr 3:13,241,217...13,306,046
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G |
Srxn1 |
sulfiredoxin 1 |
increases expression |
ISO |
Bleomycin results in increased expression of SRXN1 mRNA |
CTD |
PMID:22003191 |
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NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
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G |
Sstr1 |
somatostatin receptor 1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of SSTR1 mRNA |
CTD |
PMID:15808516 |
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NCBI chr 6:75,832,292...75,836,806
Ensembl chr 6:75,832,530...75,836,802
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G |
Sstr2 |
somatostatin receptor 2 |
decreases expression |
EXP |
Bleomycin results in decreased expression of SSTR2 mRNA |
CTD |
PMID:15808516 |
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NCBI chr10:98,664,204...98,671,370
Ensembl chr10:98,664,216...98,674,351
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G |
Sstr3 |
somatostatin receptor 3 |
decreases expression |
EXP |
Bleomycin results in decreased expression of SSTR3 mRNA |
CTD |
PMID:15808516 |
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NCBI chr 7:110,092,563...110,109,043
Ensembl chr 7:110,092,575...110,099,769
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G |
St14 |
ST14 transmembrane serine protease matriptase |
multiple interactions |
ISO |
Bleomycin results in increased expression of and results in increased activity of ST14 protein |
CTD |
PMID:26599507 |
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NCBI chr 8:29,540,805...29,581,704
Ensembl chr 8:29,540,811...29,581,517
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G |
St3gal5 |
ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
decreases expression |
ISO |
Bleomycin results in decreased expression of ST3GAL5 mRNA |
CTD |
PMID:33770205 |
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NCBI chr 4:104,134,613...104,192,558
Ensembl chr 4:104,134,613...104,192,558
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G |
Stat3 |
signal transducer and activator of transcription 3 |
multiple interactions increases expression |
ISO |
honokiol inhibits the reaction [Bleomycin results in increased expression of STAT3 protein modified form] |
CTD |
PMID:32032644 |
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NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
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G |
Stat6 |
signal transducer and activator of transcription 6 |
multiple interactions decreases response to substance |
ISO |
STAT6 protein affects the reaction [Bleomycin results in increased expression of RETNLA mRNA] STAT6 gene mutant form results in decreased susceptibility to Bleomycin |
CTD |
PMID:15322207 |
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NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495
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G |
Stk11 |
serine/threonine kinase 11 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of STK11 protein Soot inhibits the reaction [Bleomycin results in increased expression of STK11 protein] |
CTD |
PMID:31302203 |
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NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315
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G |
Stmn1 |
stathmin 1 |
increases expression |
EXP |
Bleomycin results in increased expression of STMN1 protein |
CTD |
PMID:25933445 |
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NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
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G |
Sv2b |
synaptic vesicle glycoprotein 2b |
increases expression |
EXP |
Bleomycin results in increased expression of SV2B mRNA |
CTD |
PMID:15808516 |
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NCBI chr 1:128,978,471...129,152,479
Ensembl chr 1:128,978,473...129,152,479
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G |
Tacr2 |
tachykinin receptor 2 |
decreases expression |
EXP |
Bleomycin results in decreased expression of TACR2 mRNA |
CTD |
PMID:15808516 |
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NCBI chr20:30,208,907...30,223,446
Ensembl chr20:30,208,907...30,223,446
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G |
Tagln |
transgelin |
increases expression |
EXP |
Bleomycin results in increased expression of TAGLN protein |
CTD |
PMID:25933445 |
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NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668
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G |
Tagln2 |
transgelin 2 |
increases expression |
EXP |
Bleomycin results in increased expression of TAGLN2 protein |
CTD |
PMID:25933445 |
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NCBI chr13:84,966,980...84,973,973
Ensembl chr13:84,967,009...84,973,972
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G |
Taldo1 |
transaldolase 1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of TALDO1 protein |
CTD |
PMID:25933445 |
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NCBI chr 1:196,493,634...196,503,965
Ensembl chr 1:196,493,589...196,503,974
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G |
Tbx21 |
T-box transcription factor 21 |
increases expression |
ISO |
Bleomycin results in increased expression of TBX21 mRNA |
CTD |
PMID:29033951 |
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NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831
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G |
Tcp1 |
t-complex 1 |
multiple interactions |
ISO |
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of TCP1 protein |
CTD |
PMID:29733421 |
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NCBI chr 1:47,829,061...47,836,809
Ensembl chr 1:47,828,652...47,836,839
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G |
Tent4b |
terminal nucleotidyltransferase 4B |
decreases expression |
ISO |
Bleomycin results in decreased expression of TENT4B mRNA |
CTD |
PMID:33770205 |
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NCBI chr19:18,807,616...18,868,969
Ensembl chr19:18,807,525...18,869,537
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G |
Tert |
telomerase reverse transcriptase |
decreases response to substance |
ISO |
TERT gene mutant form results in decreased susceptibility to Bleomycin |
CTD |
PMID:18008008 |
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NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561
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G |
Tf |
transferrin |
increases expression |
EXP |
Bleomycin results in increased expression of TF protein |
CTD |
PMID:25933445 |
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NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
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G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions increases expression increases secretion |
ISO EXP |
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; 5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]]; 5-hydroxydecanoic acid inhibits the reaction [Diazoxide inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]]; [Bleomycin co-treated with Cannabidiol analog] results in decreased expression of TGFB1 mRNA; [Bleomycin co-treated with Rosiglitazone] results in decreased expression of TGFB1 mRNA; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Calcitriol inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; camostat inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CCL11 protein promotes the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Diazoxide inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; honokiol inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; loganin inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; morroniside inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide promotes the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; SPL-334 inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Thioctic Acid inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein] yupingfeng inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; yupingfeng inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein] Bleomycin results in increased expression of TGFB1 mRNA; Bleomycin results in increased expression of TGFB1 protein Bleomycin results in increased secretion of TGFB1 protein andrographolide inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; angiotensin I (1-7) inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Berberine inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; pachymic acid inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Resveratrol inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Valsartan inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein] |
CTD |
PMID:14609568 PMID:15541506 PMID:16115399 PMID:16314464 PMID:17035056 PMID:17177178 PMID:17434272 PMID:19080365 PMID:19112509 PMID:19147827 PMID:20581171 PMID:22687607 PMID:23523906 PMID:26093215 PMID:26209236 PMID:26520185 PMID:26526764 PMID:26599507 PMID:27153807 PMID:27704718 PMID:28300665 PMID:28434932 PMID:28694203 PMID:29033951 PMID:29720568 PMID:30033591 PMID:30106319 PMID:31706003 PMID:31901889 PMID:32032644 PMID:35187969 PMID:35267148 PMID:35279615 PMID:35785413 PMID:37163307 PMID:37783230 PMID:37898439 More...
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NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Tgfb1i1 |
transforming growth factor beta 1 induced transcript 1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of TGFB1I1 protein |
CTD |
PMID:25933445 |
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NCBI chr 1:182,828,553...182,835,465
Ensembl chr 1:182,828,544...182,837,080
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G |
Tgfb2 |
transforming growth factor, beta 2 |
multiple interactions |
ISO |
[CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA] |
CTD |
PMID:28434932 |
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NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
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G |
Tgfb3 |
transforming growth factor, beta 3 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of TGFB3 mRNA CCL12 protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]]; Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]; HIF1A protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]]; MMP3 protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]] |
CTD |
PMID:28434932 |
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NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564
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G |
Tgfbr1 |
transforming growth factor, beta receptor 1 |
multiple interactions increases expression |
ISO |
[CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA] MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of TGFBR1 mRNA] |
CTD |
PMID:28434932 PMID:28726637 |
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NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
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G |
Tgfbr2 |
transforming growth factor, beta receptor 2 |
multiple interactions |
ISO |
[CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA] |
CTD |
PMID:28434932 |
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NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
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G |
Tgif2 |
TGFB-induced factor homeobox 2 |
increases expression |
ISO |
Bleomycin results in increased expression of TGIF2 mRNA |
CTD |
PMID:36087614 |
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NCBI chr 3:145,333,152...145,348,599
Ensembl chr 3:145,333,418...145,348,596
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G |
Thbs1 |
thrombospondin 1 |
increases expression |
ISO |
Bleomycin results in increased expression of THBS1 mRNA |
CTD |
PMID:29720568 |
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NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440
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G |
Thbs2 |
thrombospondin 2 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of THBS2 protein Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of THBS2 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of THBS2 protein] |
CTD |
PMID:30825431 |
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NCBI chr 1:55,670,394...55,699,789
Ensembl chr 1:55,670,394...55,699,789
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G |
Thop1 |
thimet oligopeptidase 1 |
decreases expression |
ISO |
Bleomycin results in decreased expression of THOP1 protein |
CTD |
PMID:29733421 |
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NCBI chr 7:8,632,911...8,645,339
Ensembl chr 7:8,632,916...8,645,275
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G |
Thrb |
thyroid hormone receptor beta |
decreases expression |
EXP |
Bleomycin results in decreased expression of THRB mRNA |
CTD |
PMID:15808516 |
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NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
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G |
Timp1 |
TIMP metallopeptidase inhibitor 1 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of TIMP1 mRNA; Bleomycin results in increased expression of TIMP1 protein Dexamethasone inhibits the reaction [Bleomycin results in increased expression of TIMP1 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of TIMP1 protein]; honokiol inhibits the reaction [Bleomycin results in increased expression of TIMP1 protein] |
CTD |
PMID:26345256 PMID:28300665 PMID:32032644 |
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NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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G |
Tlr1 |
toll-like receptor 1 |
decreases expression |
ISO |
Bleomycin results in decreased expression of TLR1 mRNA |
CTD |
PMID:29720568 |
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NCBI chr14:43,384,127...43,396,765
Ensembl chr14:43,384,932...43,397,125
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G |
Tmcc3 |
transmembrane and coiled-coil domain family 3 |
decreases expression |
ISO |
Bleomycin results in decreased expression of TMCC3 mRNA |
CTD |
PMID:33770205 |
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NCBI chr 7:28,893,972...29,171,935
Ensembl chr 7:28,893,967...29,171,926
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G |
Tmem250 |
transmembrane protein 250 |
increases expression |
ISO |
Bleomycin results in increased expression of TMEM250 mRNA |
CTD |
PMID:33770205 |
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NCBI chr 3:8,962,657...8,966,349
Ensembl chr 3:8,962,657...8,966,349
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G |
Tmem87a |
transmembrane protein 87A |
increases expression |
ISO |
Bleomycin results in increased expression of TMEM87A mRNA |
CTD |
PMID:33770205 |
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NCBI chr 3:107,307,726...107,353,571
Ensembl chr 3:107,307,726...107,353,551
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G |
Tnc |
tenascin C |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of TNC mRNA; Bleomycin results in increased expression of TNC protein Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of TNC protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of TNC protein] |
CTD |
PMID:26345256 PMID:30825431 |
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NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624
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G |
Tnf |
tumor necrosis factor |
multiple interactions increases secretion affects response to substance increases expression |
ISO EXP |
[Bleomycin co-treated with SFTPA1 protein polymorphism] results in increased expression of TNF protein; [Bleomycin co-treated with SFTPA2 protein polymorphism] results in increased expression of TNF protein; Bleomycin promotes the reaction [[SFTPA1 protein binds to SFTPA2 protein] which results in increased expression of TNF protein]; calfactant inhibits the reaction [Bleomycin promotes the reaction [[SFTPA1 protein binds to SFTPA2 protein] which results in increased expression of TNF protein]]; Ephedrine inhibits the reaction [Bleomycin results in increased secretion of TNF protein]; Ozone inhibits the reaction [[Bleomycin co-treated with SFTPA2 protein polymorphism] results in increased expression of TNF protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]; yupingfeng inhibits the reaction [Bleomycin results in increased expression of TNF mRNA] TNF protein affects the susceptibility to Bleomycin Bleomycin results in increased expression of TNF mRNA; Bleomycin results in increased expression of TNF protein [Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of TNF protein; Berberine inhibits the reaction [Bleomycin results in increased expression of TNF protein]; celastrol inhibits the reaction [Bleomycin results in increased expression of TNF protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; Resveratrol inhibits the reaction [Bleomycin results in increased expression of TNF protein]; Taurine inhibits the reaction [Bleomycin results in increased expression of TNF protein] (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of TNF protein]; [SLCO2A1 gene mutant form results in increased susceptibility to Bleomycin] which results in increased expression of TNF mRNA; [TNF protein affects the susceptibility to Bleomycin] which affects the expression of SFTPB protein; [TNF protein affects the susceptibility to Bleomycin] which affects the expression of SFTPD protein; Calcitriol inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of TNF protein]; Enalapril inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; honokiol inhibits the reaction [Bleomycin results in increased expression of TNF protein]; Oils, Volatile inhibits the reaction [Bleomycin results in increased expression of TNF protein]; pirinixic acid inhibits the reaction [Bleomycin results in increased expression of TNF protein]; PPARA protein affects the reaction [Bleomycin results in increased expression of TNF protein]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of TNF protein]; tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; Thioctic Acid inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of TNF protein]; verlukast inhibits the reaction [Bleomycin results in increased expression of TNF protein]; zileuton inhibits the reaction [Bleomycin results in increased expression of TNF protein] |
CTD |
PMID:8317554 PMID:8473757 PMID:11350791 PMID:12003776 PMID:14609568 PMID:14617519 PMID:15541506 PMID:16317386 PMID:17035056 PMID:17118201 PMID:17177178 PMID:19080365 PMID:19362168 PMID:22687607 PMID:23523906 PMID:26093215 PMID:26520185 PMID:26600069 PMID:26768587 PMID:27704718 PMID:28850077 PMID:31901889 PMID:32032644 PMID:32828905 PMID:33516805 PMID:33647319 PMID:35187969 PMID:35716765 PMID:37778983 PMID:37898439 More...
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Tnfrsf1a |
TNF receptor superfamily member 1A |
increases response to substance increases expression |
ISO |
TNFRSF1A results in increased susceptibility to Bleomycin Bleomycin results in increased expression of TNFRSF1A mRNA |
CTD |
PMID:12003776 PMID:36087614 |
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NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
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Tnfrsf1b |
TNF receptor superfamily member 1B |
increases expression increases response to substance |
EXP ISO |
Bleomycin results in increased expression of TNFRSF1B protein TNFRSF1B results in increased susceptibility to Bleomycin |
CTD |
PMID:12003776 PMID:15371238 |
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NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
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Tnfsf11 |
TNF superfamily member 11 |
decreases expression |
ISO |
Bleomycin results in decreased expression of TNFSF11 mRNA |
CTD |
PMID:29720568 |
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NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445
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Tnfsf4 |
TNF superfamily member 4 |
increases expression |
ISO |
Bleomycin results in increased expression of TNFSF4 mRNA |
CTD |
PMID:36087614 |
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NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788
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Tp53 |
tumor protein p53 |
increases expression multiple interactions increases phosphorylation increases response to substance |
ISO |
Bleomycin results in increased expression of TRP53 protein Bleomycin results in increased expression of TP53 mRNA 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin promotes the reaction [Resveratrol results in increased phosphorylation of TP53 protein]]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin results in increased phosphorylation of TP53 protein]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of TP53 protein]]; Bleomycin promotes the reaction [Polyphenols results in increased expression of TP53 mRNA]; Bleomycin promotes the reaction [Resveratrol results in increased phosphorylation of TP53 protein]; Bleomycin promotes the reaction [Tea results in increased expression of TP53 mRNA]; Polyphenols promotes the reaction [Bleomycin results in increased expression of TP53 mRNA]; Resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of TP53 protein]; Tea promotes the reaction [Bleomycin results in increased expression of TP53 mRNA] TP53 protein results in increased susceptibility to Bleomycin |
CTD |
PMID:9683175 PMID:20135637 PMID:24933654 PMID:26800624 |
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NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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Tpm1 |
tropomyosin 1 |
increases expression |
EXP |
Bleomycin results in increased expression of TPM1 protein |
CTD |
PMID:25933445 |
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NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802
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Tpm3 |
tropomyosin 3 |
increases expression |
EXP |
Bleomycin results in increased expression of TPM3 protein |
CTD |
PMID:25933445 |
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NCBI chr 2:175,517,198...175,545,014
Ensembl chr 2:175,517,226...175,545,013
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Tpm4 |
tropomyosin 4 |
increases expression |
EXP |
Bleomycin results in increased expression of TPM4 protein |
CTD |
PMID:25933445 |
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NCBI chr16:17,684,415...17,698,456
Ensembl chr16:17,683,195...17,705,984
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Tppp3 |
tubulin polymerization-promoting protein family member 3 |
decreases expression |
EXP |
Bleomycin results in decreased expression of TPPP3 protein |
CTD |
PMID:25933445 |
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NCBI chr19:33,345,897...33,349,610
Ensembl chr19:33,345,898...33,349,577
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Traf2 |
Tnf receptor-associated factor 2 |
decreases expression increases expression |
EXP ISO |
Bleomycin results in decreased expression of TRAF2 protein Bleomycin results in increased expression of TRAF2 mRNA |
CTD |
PMID:15371238 PMID:36087614 |
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NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538
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Traf3ip2 |
Traf3 interacting protein 2 |
multiple interactions |
ISO |
Calcitriol inhibits the reaction [Bleomycin results in increased phosphorylation of ACT1 protein] |
CTD |
PMID:26520185 |
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NCBI chr20:43,011,405...43,054,654
Ensembl chr20:43,011,450...43,054,667
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Trim28 |
tripartite motif-containing 28 |
increases phosphorylation |
ISO |
Bleomycin results in increased phosphorylation of TRIM28 protein |
CTD |
PMID:24933654 |
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NCBI chr 1:73,652,441...73,659,388
Ensembl chr 1:73,652,709...73,659,380
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Trpm2 |
transient receptor potential cation channel, subfamily M, member 2 |
multiple interactions |
ISO |
TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of CXCL1 protein]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of CXCL2 protein]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of IL1B protein]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of TNF protein] |
CTD |
PMID:26600069 |
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NCBI chr20:10,703,568...10,753,189
Ensembl chr20:10,707,014...10,753,181
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Tshr |
thyroid stimulating hormone receptor |
decreases expression |
EXP |
Bleomycin results in decreased expression of TSHR mRNA |
CTD |
PMID:15808516 |
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NCBI chr 6:110,341,585...110,475,297
Ensembl chr 6:110,341,581...110,474,538
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Tuba1c |
tubulin, alpha 1C |
decreases expression |
EXP |
Bleomycin results in decreased expression of TUBA1C protein |
CTD |
PMID:25933445 |
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NCBI chr 7:130,192,050...130,199,655
Ensembl chr 7:130,192,016...130,199,647 Ensembl chr X:130,192,016...130,199,647
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Tubb2a |
tubulin, beta 2A class IIa |
decreases expression |
EXP ISO |
Bleomycin results in decreased expression of TUBB2A protein Bleomycin results in decreased expression of TUBB2A mRNA |
CTD |
PMID:25933445 PMID:33770205 |
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NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714
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Tubb4b |
tubulin, beta 4B class IVb |
decreases expression |
EXP |
Bleomycin results in decreased expression of TUBB4B protein |
CTD |
PMID:25933445 |
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NCBI chr 3:8,037,838...8,040,294
Ensembl chr 3:8,037,799...8,040,296
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Twist1 |
twist family bHLH transcription factor 1 |
increases expression |
ISO |
Bleomycin results in increased expression of TWIST1 protein |
CTD |
PMID:37126650 |
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NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653
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Tymp |
thymidine phosphorylase |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of TYMP protein Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of TYMP protein] |
CTD |
PMID:30825431 |
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NCBI chr 7:120,438,768...120,444,088
Ensembl chr 7:120,438,770...120,443,874 Ensembl chr 7:120,438,770...120,443,874
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Ugcg |
UDP-glucose ceramide glucosyltransferase |
decreases expression |
ISO |
Bleomycin results in decreased expression of UGCG mRNA |
CTD |
PMID:33770205 |
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NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393
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Ulk1 |
unc-51 like autophagy activating kinase 1 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of ULK1 protein modified form Soot inhibits the reaction [Bleomycin results in increased expression of ULK1 protein modified form] |
CTD |
PMID:31302203 |
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NCBI chr12:45,851,710...45,877,966
Ensembl chr12:45,851,710...45,877,966
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Uqcrc1 |
ubiquinol-cytochrome c reductase core protein 1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of UQCRC1 protein |
CTD |
PMID:25933445 |
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NCBI chr 8:109,589,735...109,601,481
Ensembl chr 8:109,589,706...109,601,480
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Vav1 |
vav guanine nucleotide exchange factor 1 |
multiple interactions increases expression |
ISO |
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of VAV1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of VAV1 mRNA] |
CTD |
PMID:30825431 |
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NCBI chr 9:2,161,985...2,209,951
Ensembl chr 9:2,157,900...2,208,937
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Vcl |
vinculin |
decreases expression |
EXP |
Bleomycin results in decreased expression of VCL protein |
CTD |
PMID:25933445 |
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NCBI chr15:3,265,776...3,355,586
Ensembl chr15:3,265,815...3,355,606
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Vegfa |
vascular endothelial growth factor A |
increases expression |
EXP |
Bleomycin results in increased expression of VEGFA mRNA |
CTD |
PMID:26093215 |
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NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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Vegfb |
vascular endothelial growth factor B |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of VEGFB protein Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of VEGFB protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of VEGFB protein] |
CTD |
PMID:30825431 |
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NCBI chr 1:204,172,297...204,178,046
Ensembl chr 1:204,172,225...204,177,944
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Vim |
vimentin |
increases expression multiple interactions affects expression decreases expression |
EXP ISO |
Bleomycin results in increased expression of VIM protein Ephedrine inhibits the reaction [Bleomycin results in increased expression of VIM mRNA]; Ephedrine inhibits the reaction [Bleomycin results in increased expression of VIM protein] geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of VIM mRNA]; geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of VIM protein]; MIR100HG mRNA affects the reaction [Bleomycin results in increased expression of VIM mRNA]; MIR100HG mRNA affects the reaction [Bleomycin results in increased expression of VIM protein] Bleomycin results in increased expression of VIM mRNA; Bleomycin results in increased expression of VIM protein Bleomycin affects the expression of VIM protein Bleomycin results in decreased expression of VIM mRNA |
CTD |
PMID:25933445 PMID:34425168 PMID:35267148 PMID:35472619 PMID:37126650 PMID:37307957 PMID:37778983 More...
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NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
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Vwf |
von Willebrand factor |
multiple interactions decreases expression |
ISO |
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of VWF protein] |
CTD |
PMID:30825431 |
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NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539
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Wif1 |
Wnt inhibitory factor 1 |
multiple interactions decreases expression |
ISO |
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of WIF1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of WIF1 mRNA] |
CTD |
PMID:30825431 |
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NCBI chr 7:56,548,060...56,618,364
Ensembl chr 7:56,548,053...56,618,360
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Wnt1 |
Wnt family member 1 |
increases expression |
ISO |
Bleomycin results in increased expression of WNT1 mRNA |
CTD |
PMID:36087614 |
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NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651
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Wnt10a |
Wnt family member 10A |
increases expression |
ISO |
Bleomycin results in increased expression of WNT10A mRNA |
CTD |
PMID:36087614 |
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NCBI chr 9:76,349,931...76,362,400
Ensembl chr 9:76,349,931...76,362,400
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Wnt9a |
Wnt family member 9A |
increases expression |
ISO |
Bleomycin results in increased expression of WNT9A mRNA |
CTD |
PMID:36087614 |
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NCBI chr10:44,094,140...44,121,134
Ensembl chr10:44,094,140...44,121,133
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Xrcc1 |
X-ray repair cross complementing 1 |
affects response to substance decreases response to substance |
ISO |
XRCC1 gene polymorphism affects the susceptibility to Bleomycin XRCC1 results in decreased susceptibility to Bleomycin |
CTD |
PMID:12082022 PMID:20705543 |
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NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701
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Xrcc5 |
X-ray repair cross complementing 5 |
affects response to substance |
ISO |
XRCC5 protein affects the susceptibility to Bleomycin |
CTD |
PMID:12384553 |
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NCBI chr 9:73,955,216...74,044,020
Ensembl chr 9:73,955,216...74,044,018
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Yes1 |
YES proto-oncogene 1, Src family tyrosine kinase |
decreases expression |
ISO |
Bleomycin results in decreased expression of YES1 mRNA |
CTD |
PMID:33770205 |
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NCBI chr 9:113,200,256...113,275,942
Ensembl chr 9:113,200,256...113,299,837
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Ywhab |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta |
decreases expression |
EXP |
Bleomycin results in decreased expression of YWHAB protein |
CTD |
PMID:25933445 |
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NCBI chr 3:152,659,663...152,682,105
Ensembl chr 3:152,659,651...152,682,105
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Zfx |
zinc finger protein X-linked |
increases expression |
ISO |
Bleomycin results in increased expression of ZFX mRNA |
CTD |
PMID:33770205 |
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NCBI chr X:58,804,690...58,853,155
Ensembl chr X:58,804,691...58,853,265
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Abhd10 |
abhydrolase domain containing 10, depalmitoylase |
decreases expression |
ISO |
bleomycetin results in decreased expression of ABHD10 mRNA |
CTD |
PMID:21040473 |
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NCBI chr11:55,081,273...55,095,044
Ensembl chr11:55,081,049...55,107,866
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Alg12 |
ALG12, alpha-1,6-mannosyltransferase |
decreases expression |
ISO |
bleomycetin results in decreased expression of ALG12 mRNA |
CTD |
PMID:21040473 |
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NCBI chr 7:119,895,112...119,909,488
Ensembl chr 7:119,895,120...119,909,458
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Amacr |
alpha-methylacyl-CoA racemase |
decreases expression |
ISO |
bleomycetin results in decreased expression of AMACR mRNA |
CTD |
PMID:21040473 |
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NCBI chr 2:59,946,158...59,958,255
Ensembl chr 2:59,946,153...59,958,255
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Arf4 |
ADP-ribosylation factor 4 |
decreases expression |
ISO |
bleomycetin results in decreased expression of ARF4 mRNA |
CTD |
PMID:21040473 |
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NCBI chr16:1,896,692...1,913,267
Ensembl chr16:1,896,546...1,913,261
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B2m |
beta-2 microglobulin |
decreases expression |
ISO |
bleomycetin results in decreased expression of B2M mRNA |
CTD |
PMID:21040473 |
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NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
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Bmp2 |
bone morphogenetic protein 2 |
increases expression |
ISO |
bleomycetin results in increased expression of BMP2 mRNA |
CTD |
PMID:21040473 |
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NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
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Car9 |
carbonic anhydrase 9 |
increases expression multiple interactions decreases response to substance |
ISO |
bleomycetin results in increased expression of CA9 mRNA; bleomycetin results in increased expression of CA9 protein CA9 protein inhibits the reaction [bleomycetin results in increased activity of CASP3 protein] CA9 protein results in decreased susceptibility to bleomycetin |
CTD |
PMID:21040473 |
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NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838
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Casd1 |
CAS1 domain containing 1 |
decreases expression |
ISO |
bleomycetin results in decreased expression of CASD1 mRNA |
CTD |
PMID:21040473 |
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NCBI chr 4:32,659,196...32,739,228
Ensembl chr 4:32,658,748...32,739,202
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Casp1 |
caspase 1 |
decreases expression |
ISO |
bleomycetin results in decreased expression of CASP1 mRNA |
CTD |
PMID:21040473 |
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NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
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Casp3 |
caspase 3 |
multiple interactions increases activity |
ISO |
Acetazolamide promotes the reaction [bleomycetin results in increased activity of CASP3 protein]; CA9 protein inhibits the reaction [bleomycetin results in increased activity of CASP3 protein] |
CTD |
PMID:21040473 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Cdhr5 |
cadherin-related family member 5 |
decreases expression |
ISO |
bleomycetin results in decreased expression of CDHR5 mRNA |
CTD |
PMID:21040473 |
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NCBI chr 1:196,373,110...196,381,609
Ensembl chr 1:196,373,112...196,381,543
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Cox7b |
cytochrome c oxidase subunit 7B |
decreases expression |
ISO |
bleomycetin results in decreased expression of COX7B mRNA |
CTD |
PMID:21040473 |
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NCBI chr X:71,083,486...71,089,733
Ensembl chr X:71,083,456...71,089,732
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Cul4a |
cullin 4A |
increases expression |
ISO |
bleomycetin results in increased expression of CUL4A mRNA |
CTD |
PMID:21040473 |
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NCBI chr16:76,385,298...76,422,316
Ensembl chr16:76,384,546...76,422,330
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Ddit4 |
DNA-damage-inducible transcript 4 |
increases expression |
ISO |
bleomycetin results in increased expression of DDIT4 mRNA |
CTD |
PMID:21040473 |
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NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
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Dhcr24 |
24-dehydrocholesterol reductase |
decreases expression |
ISO |
bleomycetin results in decreased expression of DHCR24 mRNA |
CTD |
PMID:21040473 |
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NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137
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