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G |
Mgam |
maltase-glucoamylase |
multiple interactions increases metabolic processing |
EXP |
[MGAM protein results in increased metabolism of Maltose] which results in increased abundance of Glucose |
CTD |
PMID:17585022 |
|
NCBI chr 6:40,605,765...40,746,057
Ensembl chr 6:40,605,765...40,746,057
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G |
Slc2a2 |
solute carrier family 2 (facilitated glucose transporter), member 2 |
multiple interactions |
ISO |
Maltose inhibits the reaction [SLC2A2 protein results in increased transport of Deoxyglucose]; Maltose inhibits the reaction [SLC2A2 protein results in increased transport of Fructose] |
CTD |
PMID:8457197 |
|
NCBI chr 3:28,752,052...28,782,510
Ensembl chr 3:28,752,052...28,785,508
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G |
Slc2a3 |
solute carrier family 2 (facilitated glucose transporter), member 3 |
multiple interactions |
ISO |
Maltose inhibits the reaction [SLC2A3 protein results in increased transport of Deoxyglucose]; Maltose inhibits the reaction [SLC2A3 protein results in increased transport of Galactose] |
CTD |
PMID:8457197 |
|
NCBI chr 6:122,704,783...122,779,149
Ensembl chr 6:122,704,768...122,778,599
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|
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G |
Mgam |
maltase-glucoamylase |
increases metabolic processing multiple interactions |
EXP |
MGAM protein results in increased metabolism of Maltose [MGAM protein results in increased metabolism of Maltose] which results in increased abundance of Glucose |
CTD |
PMID:17585022 |
|
NCBI chr 6:40,605,765...40,746,057
Ensembl chr 6:40,605,765...40,746,057
|
|
G |
Slc2a2 |
solute carrier family 2 (facilitated glucose transporter), member 2 |
multiple interactions |
ISO |
Maltose inhibits the reaction [SLC2A2 protein results in increased transport of Deoxyglucose]; Maltose inhibits the reaction [SLC2A2 protein results in increased transport of Fructose] |
CTD |
PMID:8457197 |
|
NCBI chr 3:28,752,052...28,782,510
Ensembl chr 3:28,752,052...28,785,508
|
|
G |
Slc2a3 |
solute carrier family 2 (facilitated glucose transporter), member 3 |
multiple interactions |
ISO |
Maltose inhibits the reaction [SLC2A3 protein results in increased transport of Deoxyglucose]; Maltose inhibits the reaction [SLC2A3 protein results in increased transport of Galactose] |
CTD |
PMID:8457197 |
|
NCBI chr 6:122,704,783...122,779,149
Ensembl chr 6:122,704,768...122,778,599
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G |
Ace |
angiotensin I converting enzyme |
decreases expression |
ISO |
rebaudioside A results in decreased expression of ACE mRNA |
CTD |
PMID:31655124 |
|
NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790
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|
G |
Acox1 |
acyl-Coenzyme A oxidase 1, palmitoyl |
multiple interactions |
EXP |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr11:116,062,714...116,089,605
Ensembl chr11:116,062,714...116,089,871
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G |
Acta2 |
actin alpha 2, smooth muscle, aorta |
multiple interactions |
ISO |
rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of ACTA2 protein] |
CTD |
PMID:30883860 |
|
NCBI chr19:34,217,736...34,232,985
Ensembl chr19:34,218,490...34,232,990
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|
G |
Agtr1a |
angiotensin II receptor, type 1a |
increases expression |
ISO |
rebaudioside A results in increased expression of AGTR1 mRNA |
CTD |
PMID:31655124 |
|
NCBI chr13:30,520,339...30,566,850
Ensembl chr13:30,520,424...30,566,850
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G |
Alox5 |
arachidonate 5-lipoxygenase |
increases expression |
ISO |
rebaudioside A results in increased expression of ALOX5 mRNA |
CTD |
PMID:31655124 |
|
NCBI chr 6:116,387,030...116,438,139
Ensembl chr 6:116,387,038...116,438,139
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G |
Bax |
BCL2-associated X protein |
decreases expression |
ISO |
rebaudioside A results in decreased expression of BAX mRNA |
CTD |
PMID:31655124 |
|
NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
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G |
Calca |
calcitonin/calcitonin-related polypeptide, alpha |
increases expression |
ISO |
rebaudioside A results in increased expression of CALCA mRNA |
CTD |
PMID:31655124 |
|
NCBI chr 7:114,225,223...114,236,145
Ensembl chr 7:114,230,713...114,235,592
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G |
Cat |
catalase |
multiple interactions |
EXP |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
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G |
Cav1 |
caveolin 1, caveolae protein |
decreases expression |
ISO |
rebaudioside A results in decreased expression of CAV1 mRNA |
CTD |
PMID:31655124 |
|
NCBI chr 6:17,306,387...17,341,323
Ensembl chr 6:17,306,334...17,341,451
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
decreases expression |
ISO |
rebaudioside A results in decreased expression of CCL2 mRNA |
CTD |
PMID:31655124 |
|
NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
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G |
Cflar |
CASP8 and FADD-like apoptosis regulator |
decreases expression |
ISO |
rebaudioside A results in decreased expression of CFLAR mRNA |
CTD |
PMID:31655124 |
|
NCBI chr 1:58,750,353...58,798,043
Ensembl chr 1:58,750,667...58,798,043
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G |
Cpt1a |
carnitine palmitoyltransferase 1a, liver |
multiple interactions |
EXP |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr19:3,372,328...3,435,735
Ensembl chr19:3,372,334...3,435,733
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G |
Dgat2 |
diacylglycerol O-acyltransferase 2 |
multiple interactions |
EXP |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr 7:98,802,870...98,831,920
Ensembl chr 7:98,802,865...98,831,926
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G |
Edn1 |
endothelin 1 |
decreases expression |
ISO |
rebaudioside A results in decreased expression of EDN1 mRNA |
CTD |
PMID:31655124 |
|
NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
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G |
Ednra |
endothelin receptor type A |
increases expression |
ISO |
rebaudioside A results in increased expression of EDNRA mRNA |
CTD |
PMID:31655124 |
|
NCBI chr 8:78,389,658...78,451,081
Ensembl chr 8:78,389,660...78,451,093
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G |
F2r |
coagulation factor II thrombin receptor |
decreases expression |
ISO |
rebaudioside A results in decreased expression of F2R mRNA |
CTD |
PMID:31655124 |
|
NCBI chr13:95,738,288...95,754,974
Ensembl chr13:95,738,311...95,754,995
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G |
Fasl |
Fas ligand |
increases expression |
ISO |
rebaudioside A results in increased expression of FASLG mRNA |
CTD |
PMID:31655124 |
|
NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
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G |
Fgf1 |
fibroblast growth factor 1 |
increases expression |
ISO |
rebaudioside A results in increased expression of FGF1 mRNA |
CTD |
PMID:31655124 |
|
NCBI chr18:38,971,725...39,062,532
Ensembl chr18:38,971,726...39,062,525
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G |
Flt1 |
FMS-like tyrosine kinase 1 |
decreases expression |
ISO |
rebaudioside A results in decreased expression of FLT1 mRNA |
CTD |
PMID:31655124 |
|
NCBI chr 5:147,498,414...147,663,419
Ensembl chr 5:147,498,414...147,662,821
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G |
Foxo1 |
forkhead box O1 |
multiple interactions |
EXP |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642
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G |
G6pc1 |
glucose-6-phosphatase catalytic subunit 1 |
multiple interactions |
EXP |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC1 mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr11:101,258,542...101,268,729
Ensembl chr11:101,258,387...101,268,729
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G |
Il10 |
interleukin 10 |
multiple interactions |
ISO |
rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of IL10 protein] |
CTD |
PMID:30883860 |
|
NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
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G |
Il6 |
interleukin 6 |
multiple interactions |
ISO |
rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of IL6 protein] |
CTD |
PMID:30883860 |
|
NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
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G |
Insr |
insulin receptor |
multiple interactions |
EXP |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr 8:3,200,922...3,329,649
Ensembl chr 8:3,172,061...3,329,617
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G |
Irs1 |
insulin receptor substrate 1 |
multiple interactions |
EXP |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr 1:82,210,826...82,269,160
Ensembl chr 1:82,210,822...82,269,137
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G |
Irs2 |
insulin receptor substrate 2 |
multiple interactions |
EXP |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr 8:11,034,681...11,058,929
Ensembl chr 8:11,034,681...11,058,458
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G |
Itgav |
integrin alpha V |
decreases expression |
ISO |
rebaudioside A results in decreased expression of ITGAV mRNA |
CTD |
PMID:31655124 |
|
NCBI chr 2:83,554,796...83,637,261
Ensembl chr 2:83,554,741...83,637,260
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G |
Kit |
KIT proto-oncogene receptor tyrosine kinase |
decreases expression |
ISO |
rebaudioside A results in decreased expression of KIT mRNA |
CTD |
PMID:31655124 |
|
NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382
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G |
Ldlr |
low density lipoprotein receptor |
multiple interactions |
EXP |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215
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G |
Lep |
leptin |
multiple interactions |
EXP |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
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G |
Lipc |
lipase, hepatic |
multiple interactions |
EXP |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr 9:70,705,410...70,859,503
Ensembl chr 9:70,705,410...70,859,508
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G |
Mmp13 |
matrix metallopeptidase 13 |
multiple interactions |
ISO |
rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of MMP13 protein] |
CTD |
PMID:30883860 |
|
NCBI chr 9:7,272,514...7,283,333
Ensembl chr 9:7,272,514...7,283,331
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G |
Mmp2 |
matrix metallopeptidase 2 |
multiple interactions |
ISO |
rebaudioside A inhibits the reaction [Thioacetamide results in increased activity of MMP2 protein] |
CTD |
PMID:30883860 |
|
NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048
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G |
Mmp9 |
matrix metallopeptidase 9 |
increases expression multiple interactions |
ISO |
rebaudioside A results in increased expression of MMP9 mRNA rebaudioside A inhibits the reaction [Thioacetamide results in increased activity of MMP9 protein] |
CTD |
PMID:30883860 PMID:31655124 |
|
NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
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G |
Mtor |
mechanistic target of rapamycin kinase |
multiple interactions |
EXP |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140
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|
G |
Nfe2l2 |
nuclear factor, erythroid derived 2, like 2 |
multiple interactions |
ISO |
rebaudioside A inhibits the reaction [Thioacetamide results in decreased expression of NFE2L2 protein] |
CTD |
PMID:30883860 |
|
NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
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G |
Nfkb1 |
nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 |
multiple interactions |
EXP |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308
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G |
Nfkbia |
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha |
multiple interactions |
EXP |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
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G |
Pck1 |
phosphoenolpyruvate carboxykinase 1, cytosolic |
multiple interactions |
EXP |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr 2:172,994,866...173,001,067
Ensembl chr 2:172,994,841...173,001,066
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G |
Pf4 |
platelet factor 4 |
increases expression |
ISO |
rebaudioside A results in increased expression of PF4 mRNA |
CTD |
PMID:31655124 |
|
NCBI chr 5:90,920,362...90,921,242
Ensembl chr 5:90,920,294...90,921,242
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions |
EXP |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
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G |
Ppard |
peroxisome proliferator activator receptor delta |
multiple interactions |
EXP |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr17:28,451,715...28,520,446
Ensembl chr17:28,451,674...28,520,448
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G |
Pparg |
peroxisome proliferator activated receptor gamma |
multiple interactions |
EXP |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
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|
G |
Ppargc1a |
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha |
multiple interactions |
EXP |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
decreases expression |
ISO |
rebaudioside A results in decreased expression of PTGS2 mRNA |
CTD |
PMID:31655124 |
|
NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
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G |
Rela |
v-rel reticuloendotheliosis viral oncogene homolog A (avian) |
multiple interactions |
ISO |
rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of RELA protein] |
CTD |
PMID:30883860 |
|
NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
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|
G |
Scd1 |
stearoyl-Coenzyme A desaturase 1 |
multiple interactions |
EXP |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr19:44,382,889...44,396,148
Ensembl chr19:44,382,894...44,396,318
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G |
Sele |
selectin, endothelial cell |
decreases expression |
ISO |
rebaudioside A results in decreased expression of SELE mRNA |
CTD |
PMID:31655124 |
|
NCBI chr 1:163,867,200...163,886,056
Ensembl chr 1:163,875,773...163,885,246
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|
G |
Sirt1 |
sirtuin 1 |
multiple interactions |
EXP |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483
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|
G |
Slc27a1 |
solute carrier family 27 (fatty acid transporter), member 1 |
multiple interactions |
EXP |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr 8:72,021,372...72,039,951
Ensembl chr 8:72,021,526...72,039,946
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|
G |
Slc2a2 |
solute carrier family 2 (facilitated glucose transporter), member 2 |
multiple interactions |
EXP |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr 3:28,752,052...28,782,510
Ensembl chr 3:28,752,052...28,785,508
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|
G |
Smad7 |
SMAD family member 7 |
multiple interactions |
ISO |
rebaudioside A inhibits the reaction [Thioacetamide results in decreased expression of SMAD7 protein] |
CTD |
PMID:30883860 |
|
NCBI chr18:75,500,436...75,529,006
Ensembl chr18:75,500,600...75,529,006
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|
G |
Sod2 |
superoxide dismutase 2, mitochondrial |
multiple interactions |
EXP |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] |
CTD |
PMID:25554529 |
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NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
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G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions |
ISO |
rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of TGFB1 protein] |
CTD |
PMID:30883860 |
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NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of TNF protein] |
CTD |
PMID:30883860 |
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NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
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G |
Tnfsf10 |
tumor necrosis factor (ligand) superfamily, member 10 |
decreases expression |
ISO |
rebaudioside A results in decreased expression of TNFSF10 mRNA |
CTD |
PMID:31655124 |
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NCBI chr 3:27,371,226...27,393,814
Ensembl chr 3:27,371,177...27,396,576
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G |
Bax |
BCL2-associated X protein |
multiple interactions |
ISO |
royal jelly inhibits the reaction [Fluorides results in decreased expression of BAX protein] |
CTD |
PMID:34227456 |
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NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
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G |
Bcl2 |
B cell leukemia/lymphoma 2 |
multiple interactions |
EXP ISO |
royal jelly inhibits the reaction [Nicotine results in decreased expression of BCL2 mRNA] royal jelly inhibits the reaction [Fluorides results in increased expression of BCL2 protein] |
CTD |
PMID:30896085 PMID:34227456 |
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NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
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G |
Bdnf |
brain derived neurotrophic factor |
multiple interactions |
ISO |
royal jelly inhibits the reaction [Fluorides results in decreased expression of BDNF protein] |
CTD |
PMID:34227456 |
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NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352
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G |
Casp3 |
caspase 3 |
multiple interactions |
EXP ISO |
royal jelly inhibits the reaction [Nicotine results in increased expression of CASP3 mRNA] royal jelly inhibits the reaction [Fluorides results in decreased expression of CASP3 protein] |
CTD |
PMID:30896085 PMID:34227456 |
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NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
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G |
Casp6 |
caspase 6 |
multiple interactions |
ISO |
royal jelly inhibits the reaction [Fluorides results in decreased expression of CASP6 protein] |
CTD |
PMID:34227456 |
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NCBI chr 3:129,695,064...129,707,761
Ensembl chr 3:129,695,074...129,707,752
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G |
Casp9 |
caspase 9 |
multiple interactions |
ISO |
royal jelly inhibits the reaction [Fluorides results in decreased expression of CASP9 protein] |
CTD |
PMID:34227456 |
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NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
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G |
Cat |
catalase |
multiple interactions |
ISO EXP |
royal jelly inhibits the reaction [Cisplatin results in decreased activity of CAT protein]; royal jelly inhibits the reaction [Fluorides results in decreased activity of CAT protein] royal jelly inhibits the reaction [Nicotine results in decreased activity of CAT protein] |
CTD |
PMID:20369241 PMID:30896085 PMID:34227456 |
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NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
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G |
Ccnd1 |
cyclin D1 |
multiple interactions |
EXP |
royal jelly inhibits the reaction [phenylhydrazine affects the expression of CCND1 mRNA] |
CTD |
PMID:35099105 |
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NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
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G |
Cyp4a14 |
cytochrome P450, family 4, subfamily a, polypeptide 14 |
affects expression |
EXP |
royal jelly affects the expression of CYP4A14 mRNA |
CTD |
PMID:16161764 |
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NCBI chr 4:115,343,397...115,353,355
Ensembl chr 4:115,343,397...115,353,339
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G |
E2f1 |
E2F transcription factor 1 |
multiple interactions |
ISO |
royal jelly inhibits the reaction [Paclitaxel results in increased expression of E2F1 mRNA] |
CTD |
PMID:27496854 |
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NCBI chr 2:154,401,320...154,411,812
Ensembl chr 2:154,401,327...154,411,812
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G |
Esr1 |
estrogen receptor 1 (alpha) |
multiple interactions affects binding increases activity |
ISO |
Estradiol inhibits the reaction [royal jelly binds to ESR1 protein]; royal jelly binds to and results in increased activity of ESR1 protein; royal jelly inhibits the reaction [Estradiol binds to ESR1 protein] royal jelly results in increased activity of ESR1 protein |
CTD |
PMID:15946813 PMID:17287592 |
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NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
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G |
Esr2 |
estrogen receptor 2 (beta) |
multiple interactions affects binding |
ISO |
Estradiol inhibits the reaction [royal jelly binds to ESR2 protein]; royal jelly binds to and results in increased activity of ESR2 protein; royal jelly inhibits the reaction [Estradiol binds to ESR2 protein] |
CTD |
PMID:15946813 PMID:17287592 |
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NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions |
ISO |
royal jelly inhibits the reaction [Fluorides results in increased expression of GSK3B protein] |
CTD |
PMID:34227456 |
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NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446
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G |
Ins1 |
insulin I |
multiple interactions |
ISO |
royal jelly inhibits the reaction [Fructose results in increased expression of INS1 protein] |
CTD |
PMID:18981581 |
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NCBI chr19:52,252,735...52,253,453
Ensembl chr19:52,252,735...52,253,914
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G |
Myc |
myelocytomatosis oncogene |
multiple interactions decreases expression |
EXP ISO |
royal jelly inhibits the reaction [phenylhydrazine results in decreased expression of MYC mRNA] royal jelly inhibits the reaction [Paclitaxel results in decreased expression of MYC mRNA] royal jelly results in decreased expression of MYC mRNA |
CTD |
PMID:27496854 PMID:35099105 |
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NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223
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G |
Nfe2l2 |
nuclear factor, erythroid derived 2, like 2 |
multiple interactions |
ISO |
royal jelly inhibits the reaction [Fluorides results in decreased expression of NFE2L2 protein] |
CTD |
PMID:34227456 |
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NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
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G |
Pcna |
proliferating cell nuclear antigen |
multiple interactions |
EXP |
royal jelly inhibits the reaction [Nicotine results in decreased expression of PCNA protein] |
CTD |
PMID:30896085 |
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NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
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G |
Rela |
v-rel reticuloendotheliosis viral oncogene homolog A (avian) |
multiple interactions |
ISO |
royal jelly inhibits the reaction [Fluorides results in increased expression of RELA protein] |
CTD |
PMID:34227456 |
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NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
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G |
Tff1 |
trefoil factor 1 |
increases expression |
ISO |
royal jelly results in increased expression of TFF1 mRNA |
CTD |
PMID:15946813 |
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NCBI chr17:31,380,369...31,384,034
Ensembl chr17:31,380,369...31,384,251
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G |
Trp53 |
transformation related protein 53 |
multiple interactions |
EXP |
royal jelly inhibits the reaction [Nicotine results in increased expression of TRP53 mRNA] |
CTD |
PMID:30896085 |
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NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
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G |
Vegfa |
vascular endothelial growth factor A |
increases expression |
ISO |
royal jelly results in increased expression of VEGFA mRNA |
CTD |
PMID:15946813 PMID:17287592 |
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NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
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