The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
5,7,3'-trihydroxy-3,4'-dimethoxyflavone affects the phosphorylation of CCNB1 protein 5,7,3'-trihydroxy-3,4'-dimethoxyflavone results in increased expression of CCNB1 protein
5,7-dimethoxyflavone inhibits the reaction [ABCB1 protein results in decreased uptake of Daunorubicin]; 5,7-dimethoxyflavone inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]; 5,7-dimethoxyflavone inhibits the reaction [Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]]
5,7-dimethoxyflavone inhibits the reaction [Diethylnitrosamine results in increased expression of CCND1 mRNA]; 5,7-dimethoxyflavone inhibits the reaction [Diethylnitrosamine results in increased expression of CCND1 protein]
5,7-dimethoxyflavone inhibits the reaction [Diethylnitrosamine results in increased expression of CSNK2B mRNA]; 5,7-dimethoxyflavone inhibits the reaction [Diethylnitrosamine results in increased expression of CSNK2B protein]
5,7-dimethoxyflavone inhibits the reaction [Diethylnitrosamine affects the localization of CTNNB1 protein modified form]; 5,7-dimethoxyflavone inhibits the reaction [Diethylnitrosamine results in increased expression of CTNNB1 mRNA]
5,7-dimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1A1 protein]; 5,7-dimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; 5,7-dimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein] 5,7-dimethoxyflavone results in decreased activity of CYP1A1 protein
5,7-dimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1B1 protein]; 5,7-dimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; 5,7-dimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein] 5,7-dimethoxyflavone results in decreased activity of CYP1B1 protein
5,7-dimethoxyflavone inhibits the reaction [IL1B protein results in increased secretion of CCL2 protein]; 5,7-dimethoxyflavone inhibits the reaction [IL1B protein results in increased secretion of CXCL8 protein]; 5,7-dimethoxyflavone inhibits the reaction [IL1B protein results in increased secretion of IL6 protein]
5,7-dimethoxyflavone inhibits the reaction [Diethylnitrosamine results in increased expression of PTGS2 mRNA]; 5,7-dimethoxyflavone inhibits the reaction [Diethylnitrosamine results in increased expression of PTGS2 protein]
5,7-dimethoxyflavone inhibits the reaction [Diethylnitrosamine results in increased expression of RELA mRNA]; 5,7-dimethoxyflavone inhibits the reaction [Diethylnitrosamine results in increased expression of RELA protein modified form]
[5,7-dimethoxyflavone co-treated with Diethylnitrosamine] results in increased expression of TP53 mRNA; [5,7-dimethoxyflavone co-treated with Diethylnitrosamine] results in increased expression of TP53 protein
cirsiliol results in decreased activity of CYP1A1 protein CYP1A1 protein results in increased metabolism of cirsiliol cirsiliol results in increased expression of CYP1A1 mRNA
cirsiliol results in increased expression of CYP1B1 mRNA CYP1B1 protein results in increased metabolism of cirsiliol cirsiliol results in decreased activity of CYP1B1 protein
jaceosidin results in decreased expression of CFLAR mRNA; jaceosidin results in decreased expression of CFLAR protein CFLAR protein inhibits the reaction [jaceosidin results in increased cleavage of PARP1 protein]; RELA protein inhibits the reaction [jaceosidin results in decreased expression of CFLAR protein]; SP1 protein inhibits the reaction [jaceosidin results in decreased expression of CFLAR protein]
jaceosidin results in decreased expression of MCL1 mRNA; jaceosidin results in decreased expression of MCL1 protein MCL1 protein inhibits the reaction [jaceosidin results in increased cleavage of PARP1 protein]; RELA protein inhibits the reaction [jaceosidin results in decreased expression of MCL1 protein]; SP1 protein inhibits the reaction [jaceosidin results in decreased expression of MCL1 protein]
jaceosidin results in increased cleavage of PARP1 protein benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [jaceosidin results in increased cleavage of PARP1 protein]; CFLAR protein inhibits the reaction [jaceosidin results in increased cleavage of PARP1 protein]; MCL1 protein inhibits the reaction [jaceosidin results in increased cleavage of PARP1 protein]
RELA protein inhibits the reaction [jaceosidin results in decreased expression of CFLAR protein]; RELA protein inhibits the reaction [jaceosidin results in decreased expression of MCL1 protein]
SP1 protein inhibits the reaction [jaceosidin results in decreased expression of CFLAR protein]; SP1 protein inhibits the reaction [jaceosidin results in decreased expression of MCL1 protein]
pectolinarigenin results in increased phosphorylation of ATM protein TOP2A protein affects the reaction [pectolinarigenin results in increased phosphorylation of ATM protein]
pectolinarigenin results in increased expression of H2AX protein TOP2A protein affects the reaction [pectolinarigenin results in increased expression of H2AX protein]
Chloroquine promotes the reaction [pectolinarigenin results in increased lipidation of MAP1LC3B protein]; pectolinarigenin promotes the reaction [Chloroquine results in increased lipidation of MAP1LC3B protein]; TOP2A protein affects the reaction [pectolinarigenin results in increased lipidation of MAP1LC3B protein]
pectolinarigenin results in increased expression of SQSTM1 protein Chloroquine promotes the reaction [pectolinarigenin results in increased expression of SQSTM1 protein]; pectolinarigenin promotes the reaction [Chloroquine results in increased expression of SQSTM1 protein]
pectolinarigenin binds to and results in increased expression of TOP2A protein; TOP2A protein affects the reaction [pectolinarigenin results in increased expression of CDKN1A protein]; TOP2A protein affects the reaction [pectolinarigenin results in increased expression of H2AX protein]; TOP2A protein affects the reaction [pectolinarigenin results in increased expression of TP53 protein]; TOP2A protein affects the reaction [pectolinarigenin results in increased lipidation of MAP1LC3B protein]; TOP2A protein affects the reaction [pectolinarigenin results in increased phosphorylation of ATM protein]
pectolinarigenin results in increased expression of TP53 protein TOP2A protein affects the reaction [pectolinarigenin results in increased expression of TP53 protein]