CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: (\{[(2R,3S,4R,5R)-3,4-dihydroxy-5-(9H-purin-9-yl)oxolan-2-yl]methyl phosphonato\}oxy)(phosphonatooxy)phosphinate
Accession: CHEBI:237958
browse the term
Synonyms: cyclic_relationship: is_conjugate_acid_of CHEBI:57299
G
Cd80
Cd80 molecule
increases expression
ISO
adenosine 5'-O-(3-thiotriphosphate) results in increased expression of CD80 protein
CTD
PMID:15944274
NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030
G
Cd86
CD86 molecule
increases expression
ISO
adenosine 5'-O-(3-thiotriphosphate) results in increased expression of CD86 protein
CTD
PMID:15944274
NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
G
Il10
interleukin 10
decreases expression
ISO
adenosine 5'-O-(3-thiotriphosphate) results in decreased expression of IL10 protein
CTD
PMID:15944274
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
G
Il12b
interleukin 12B
increases expression
ISO
adenosine 5'-O-(3-thiotriphosphate) results in increased expression of IL12B protein
CTD
PMID:15944274
NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
G
Il1b
interleukin 1 beta
increases expression
ISO
adenosine 5'-O-(3-thiotriphosphate) results in increased expression of IL1B protein
CTD
PMID:15944274
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
G
P2rx7
purinergic receptor P2X 7
affects response to substance
ISO
P2RX7 protein affects the susceptibility to adenosine 5'-O-(3-thiotriphosphate)
CTD
PMID:12873706
NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
G
Ptgdr
prostaglandin D2 receptor
multiple interactions
ISO
adenosine 5'-O-(3-thiotriphosphate) inhibits the reaction [Prostaglandin D2 binds to PTGDR protein]
CTD
PMID:9579725
NCBI chr15:17,360,304...17,367,679
Ensembl chr15:17,360,304...17,367,679
G
Trpv1
transient receptor potential cation channel, subfamily V, member 1
increases activity multiple interactions
EXP
adenosine 5'-O-(3-thiotriphosphate) results in increased activity of TRPV1 protein Capsaicin promotes the reaction [adenosine 5'-O-(3-thiotriphosphate) results in increased activity of TRPV1 protein]; capsazepine inhibits the reaction [adenosine 5'-O-(3-thiotriphosphate) results in increased activity of TRPV1 protein]
CTD
PMID:11140687
NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
G
P2rx1
purinergic receptor P2X 1
affects binding
EXP
TNP-ATP binds to P2rx1 protein
RGD
PMID:12237343
RGD:727431
NCBI chr10:57,618,586...57,633,648
Ensembl chr10:57,618,586...57,633,623
G
P2rx2
purinergic receptor P2X 2
multiple interactions
EXP
TNP-ATP binds to P2rx2 protein; TNP-ATP inhibits the reaction [ATP binds to P2rx2 protein] in transfected glial cells
RGD
PMID:16388598
RGD:1642662
NCBI chr12:46,338,979...46,342,891
Ensembl chr12:46,339,549...46,342,891
G
P2rx5
purinergic receptor P2X 5
affects transport
EXP
TNP-ATP affects transport ion flux of P2rx5 receptor
RGD
PMID:12237343
RGD:727431
NCBI chr10:57,777,737...57,789,426
Ensembl chr10:57,777,819...57,789,423
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