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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:trimedoxime bromide
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Accession:CHEBI:233584 term browser browse the term
Synonyms:related_synonym: Formula=C15H16N4O2.HBr.HBr;   InChI=1S/C15H16N4O2.2BrH/c20-16-12-14-2-8-18(9-3-14)6-1-7-19-10-4-15(5-11-19)13-17-21;;/h2-5,8-13H,1,6-7H2;2*1H;   InChIKey=JHZHWVQTOXIXIV-UHFFFAOYSA-N;   SMILES=Br.Br.O=NC=C1C=CN(C=C1)CCCN2C=CC(=CN=O)C=C2
 xref: CAS:56-97-3
 xref_mesh: MESH:D014289
 xref: PMID:39292449


show annotations for term's descendants           Sort by:
trimedoxime bromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions ISO
EXP 		[asoxime chloride co-treated with Trimedoxime] inhibits the reaction [VX-agent results in decreased activity of ACHE protein]; Trimedoxime inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; Trimedoxime inhibits the reaction [heptenophos results in decreased activity of ACHE protein]; Trimedoxime inhibits the reaction [malaoxon results in decreased activity of ACHE protein]; Trimedoxime inhibits the reaction [VX-agent results in decreased activity of ACHE protein]
[asoxime chloride co-treated with Trimedoxime] inhibits the reaction [VX-agent results in decreased activity of ACHE protein]; [Trimedoxime co-treated with asoxime chloride] results in decreased susceptibility to [tabun results in decreased activity of ACHE protein]; Trimedoxime inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; Trimedoxime inhibits the reaction [Paraoxon results in decreased activity of ACHE protein]; Trimedoxime inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; Trimedoxime inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Trimedoxime inhibits the reaction [tabun results in decreased activity of ACHE protein]; Trimedoxime inhibits the reaction [VX-agent analog results in decreased activity of ACHE protein]; Trimedoxime inhibits the reaction [VX-agent results in decreased activity of ACHE protein]; Trimedoxime results in decreased susceptibility to [tabun results in decreased activity of ACHE protein]
Trimedoxime affects the reaction [Sarin results in decreased activity of ACHE protein]; Trimedoxime affects the reaction [VX-agent results in decreased activity of ACHE protein]; Trimedoxime binds to and results in decreased activity of ACHE protein; Trimedoxime inhibits the reaction [ethylparaoxon results in decreased activity of ACHE protein]; Trimedoxime inhibits the reaction [Isoflurophate results in decreased activity of ACHE protein]; Trimedoxime inhibits the reaction [leptophos oxon results in decreased activity of ACHE protein]; Trimedoxime inhibits the reaction [methamidophos results in decreased activity of ACHE protein]; Trimedoxime inhibits the reaction [Paraoxon results in decreased activity of ACHE protein]; Trimedoxime inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Trimedoxime inhibits the reaction [tabun results in decreased activity of ACHE protein] 		CTD PMID:15679473 PMID:16025528 PMID:16092078 PMID:18344198 PMID:18617161 More... NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410 		JBrowse link
G Bche butyrylcholinesterase multiple interactions ISO Trimedoxime affects the reaction [Sarin results in decreased activity of BCHE protein]; Trimedoxime affects the reaction [VX-agent results in decreased activity of BCHE protein]; Trimedoxime binds to and results in decreased activity of BCHE protein; Trimedoxime inhibits the reaction [Paraoxon results in decreased activity of BCHE protein]; Trimedoxime inhibits the reaction [tabun results in decreased activity of BCHE protein] CTD PMID:18617161 PMID:27693733 PMID:38446233 NCBI chr 2:160,607,289...160,699,760
Ensembl chr 2:160,606,288...160,699,760 		JBrowse link
G Pon1 paraoxonase 1 multiple interactions EXP Trimedoxime inhibits the reaction [Dichlorvos results in decreased activity of PON1 protein] CTD PMID:29098328 NCBI chr 4:34,261,312...34,292,327
Ensembl chr 4:34,261,289...34,287,924 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    role 20820
      biological role 20818
        biochemical role 20264
          enzyme reactivator 25
            cholinesterase reactivator 25
              trimedoxime bromide 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    main group molecular entity 20781
                      p-block molecular entity 20781
                        carbon group molecular entity 20715
                          organic molecular entity 20710
                            trimedoxime bromide 3
paths to the root