|
G |
Abcb1b |
ATP-binding cassette, sub-family B member 1B |
affects expression |
EXP |
cadmium acetate affects the expression of ABCB1B mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 4:26,197,706...26,280,156
|
|
G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
affects expression |
EXP |
cadmium acetate affects the expression of ABCC2 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 1:252,613,875...252,672,459
|
|
G |
Acot2 |
acyl-CoA thioesterase 2 |
affects expression |
EXP |
cadmium acetate affects the expression of ACOT2 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 6:109,341,426...109,352,818
|
|
G |
Actg2 |
actin gamma 2, smooth muscle |
decreases expression |
ISO |
cadmium acetate results in decreased expression of ACTG2 mRNA |
CTD |
PMID:18155341 |
|
NCBI chr 4:116,021,832...116,046,475
|
|
G |
Agpat1 |
1-acylglycerol-3-phosphate O-acyltransferase 1 |
increases expression |
ISO |
cadmium acetate results in increased expression of AGPAT1 mRNA |
CTD |
PMID:12965115 |
|
NCBI chr20:4,135,955...4,144,880
|
|
G |
Aifm1 |
apoptosis inducing factor, mitochondria associated 1 |
multiple interactions affects localization |
EXP |
pyrazolanthrone inhibits the reaction [cadmium acetate affects the localization of AIFM1 protein]; U 0126 inhibits the reaction [cadmium acetate affects the localization of AIFM1 protein] |
CTD |
PMID:24577723 PMID:25043952 |
|
NCBI chr X:132,528,107...132,567,237
|
|
G |
Akr1c3 |
aldo-keto reductase family 1, member C3 |
multiple interactions increases expression |
ISO |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cadmium acetate results in increased expression of AKR1C3 protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of AKR1C3 protein]; Cycloheximide inhibits the reaction [cadmium acetate results in increased expression of AKR1C3 protein] cadmium acetate results in increased expression of AKR1C3 mRNA; cadmium acetate results in increased expression of AKR1C3 protein |
CTD |
PMID:21787718 |
|
NCBI chr17:71,020,884...71,037,779
|
|
G |
Akt1 |
AKT serine/threonine kinase 1 |
increases phosphorylation multiple interactions increases oxidation |
ISO |
cadmium acetate results in increased phosphorylation of AKT1 protein Acetylcysteine inhibits the reaction [cadmium acetate results in decreased expression of AKT1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [cadmium acetate results in decreased expression of AKT1 protein]; cadmium acetate results in decreased expression of and results in decreased phosphorylation of AKT1 protein cadmium acetate results in increased oxidation of AKT1 protein Acetylcysteine inhibits the reaction [cadmium acetate results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:21787718 PMID:24933620 |
|
NCBI chr 6:137,534,810...137,555,131
|
|
G |
Alad |
aminolevulinate dehydratase |
multiple interactions increases activity |
EXP |
[cadmium acetate results in increased activity of ALAD protein] which results in increased chemical synthesis of Porphobilinogen; cadmium acetate inhibits the reaction [Dithiothreitol results in increased activity of ALAD protein] |
CTD |
PMID:21360559 |
|
NCBI chr 5:75,961,993...75,972,334
|
|
G |
Apex1 |
apurinic/apyrimidinic endodeoxyribonuclease 1 |
affects expression |
EXP |
cadmium acetate affects the expression of APEX1 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr15:24,144,595...24,146,785
|
|
G |
Atf4 |
activating transcription factor 4 |
multiple interactions increases expression |
EXP |
Chloroquine promotes the reaction [cadmium acetate results in increased expression of ATF4 protein]; KN 93 inhibits the reaction [cadmium acetate results in increased expression of ATF4 protein]; Sirolimus inhibits the reaction [cadmium acetate results in increased expression of ATF4 protein]; Thioctic Acid inhibits the reaction [cadmium acetate results in increased expression of ATF4 protein] |
CTD |
PMID:29870746 PMID:29883672 PMID:30605698 |
|
NCBI chr 7:113,684,681...113,686,739
|
|
G |
Atg5 |
autophagy related 5 |
increases expression multiple interactions |
EXP |
cadmium acetate results in increased expression of ATG5 protein [Sirolimus co-treated with cadmium acetate] results in increased expression of ATG5 mRNA; Chloroquine inhibits the reaction [cadmium acetate results in increased expression of ATG5 protein] |
CTD |
PMID:29870746 |
|
NCBI chr20:49,380,835...49,471,826
|
|
G |
B4galt2 |
beta-1,4-galactosyltransferase 2 |
increases expression |
ISO |
cadmium acetate results in increased expression of B4GALT2 mRNA |
CTD |
PMID:18155341 |
|
NCBI chr 5:131,412,541...131,422,573
|
|
G |
Bax |
BCL2 associated X, apoptosis regulator |
increases cleavage multiple interactions increases expression |
ISO EXP |
cadmium acetate results in increased cleavage of BAX protein 2-aminoethoxydiphenylborane inhibits the reaction [cadmium acetate results in increased expression of BAX protein]; puerarin inhibits the reaction [cadmium acetate results in increased expression of BAX mRNA]; puerarin inhibits the reaction [cadmium acetate results in increased expression of BAX protein]; pyrazolanthrone inhibits the reaction [cadmium acetate results in increased expression of BAX protein]; salubrinal inhibits the reaction [cadmium acetate results in increased expression of BAX protein]; Thioctic Acid inhibits the reaction [cadmium acetate results in increased expression of BAX protein]; U 0126 inhibits the reaction [cadmium acetate results in increased expression of BAX protein] cadmium acetate results in increased expression of BAX mRNA; cadmium acetate results in increased expression of BAX protein Acetylcysteine inhibits the reaction [cadmium acetate results in increased cleavage of BAX protein]; CAPNS1 affects the reaction [cadmium acetate results in increased cleavage of BAX protein] |
CTD |
PMID:12965115 PMID:16169029 PMID:24577723 PMID:25043952 PMID:27717697 PMID:29883672 PMID:30605698 More...
|
|
NCBI chr 1:105,076,472...105,081,906
|
|
G |
Bcl2 |
BCL2, apoptosis regulator |
increases expression decreases expression multiple interactions |
ISO EXP |
cadmium acetate results in increased expression of BCL2 protein cadmium acetate results in decreased expression of BCL2 mRNA; cadmium acetate results in decreased expression of BCL2 protein 2-aminoethoxydiphenylborane inhibits the reaction [cadmium acetate results in decreased expression of BCL2 protein]; puerarin inhibits the reaction [cadmium acetate results in decreased expression of BCL2 mRNA]; puerarin inhibits the reaction [cadmium acetate results in decreased expression of BCL2 protein]; pyrazolanthrone inhibits the reaction [cadmium acetate results in decreased expression of BCL2 protein]; salubrinal inhibits the reaction [cadmium acetate results in decreased expression of BCL2 protein]; Thioctic Acid inhibits the reaction [cadmium acetate results in decreased expression of BCL2 protein]; U 0126 inhibits the reaction [cadmium acetate results in decreased expression of BCL2 protein] |
CTD |
PMID:15450950 PMID:24577723 PMID:25043952 PMID:27717697 PMID:29883672 PMID:30605698 More...
|
|
NCBI chr13:23,204,464...23,366,900
|
|
G |
Bcl2l1 |
Bcl2-like 1 |
affects expression |
EXP |
cadmium acetate affects the expression of BCL2L1 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 3:161,713,777...161,764,844
|
|
G |
Bcl6 |
BCL6, transcription repressor |
increases expression |
ISO |
cadmium acetate results in increased expression of BCL6 mRNA |
CTD |
PMID:18155341 |
|
NCBI chr11:76,854,090...76,877,389
|
|
G |
Becn1 |
beclin 1 |
multiple interactions increases expression decreases expression |
EXP |
[Sirolimus co-treated with cadmium acetate] results in increased expression of BECN1 mRNA; Chloroquine inhibits the reaction [cadmium acetate results in increased expression of BECN1 protein]; U 0126 inhibits the reaction [cadmium acetate results in increased expression of BECN1 protein] cadmium acetate results in decreased expression of BECN1 protein |
CTD |
PMID:29870746 PMID:34897960 |
|
NCBI chr10:86,731,649...86,747,002
|
|
G |
Bid |
BH3 interacting domain death agonist |
increases cleavage multiple interactions |
ISO |
cadmium acetate results in increased cleavage of BID protein Acetylcysteine inhibits the reaction [cadmium acetate results in increased cleavage of BID protein]; cadmium acetate results in increased cleavage of and results in increased localization of BID protein; CASP8 affects the reaction [cadmium acetate results in increased cleavage of BID protein]; isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone analog inhibits the reaction [cadmium acetate results in increased cleavage of BID protein] |
CTD |
PMID:15450950 PMID:16169029 |
|
NCBI chr 4:155,785,366...155,808,775
|
|
G |
Bmpr1a |
bone morphogenetic protein receptor type 1A |
decreases expression |
ISO |
cadmium acetate results in decreased expression of BMPR1A mRNA |
CTD |
PMID:18155341 |
|
NCBI chr16:9,740,751...9,786,861
|
|
G |
Capn1 |
calpain 1 |
increases expression multiple interactions |
EXP |
cadmium acetate results in increased expression of CAPN1 protein 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [cadmium acetate results in increased expression of CAPN1 protein]; 2-aminoethyl diphenylborinate inhibits the reaction [cadmium acetate results in increased expression of CAPN1 protein]; Thapsigargin promotes the reaction [cadmium acetate results in increased expression of CAPN1 protein] |
CTD |
PMID:28347754 |
|
NCBI chr 1:212,705,219...212,736,134
|
|
G |
Capns1 |
calpain, small subunit 1 |
increases expression multiple interactions increases cleavage |
ISO |
cadmium acetate results in increased expression of CAPNS1 protein cadmium acetate results in increased cleavage of and results in increased activity of CAPNS1 protein; CAPNS1 affects the reaction [cadmium acetate results in increased cleavage of BAX protein] cadmium acetate results in increased cleavage of CAPNS1 protein |
CTD |
PMID:15450950 PMID:16169029 |
|
NCBI chr 1:85,444,613...85,454,861
|
|
G |
Casp1 |
caspase 1 |
increases cleavage multiple interactions |
EXP |
cadmium acetate results in increased cleavage of CASP1 protein Acetylcysteine inhibits the reaction [cadmium acetate results in increased cleavage of CASP1 protein] |
CTD |
PMID:36347317 |
|
NCBI chr 8:10,746,338...10,882,295
|
|
G |
Casp12 |
caspase 12 |
increases expression increases cleavage multiple interactions |
EXP |
cadmium acetate results in increased expression of CASP12 protein cadmium acetate results in increased cleavage of CASP12 protein 2-aminoethoxydiphenylborane inhibits the reaction [cadmium acetate results in increased cleavage of CASP12 protein]; Caspase Inhibitors inhibits the reaction [cadmium acetate results in increased expression of CASP12 protein modified form]; Chloroquine promotes the reaction [cadmium acetate results in increased expression of CASP12 protein]; KN 93 inhibits the reaction [cadmium acetate results in increased cleavage of CASP12 protein]; Sirolimus inhibits the reaction [cadmium acetate results in increased expression of CASP12 protein]; U 0126 promotes the reaction [cadmium acetate results in increased expression of CASP12 protein] |
CTD |
PMID:29870746 PMID:29883672 PMID:30605698 |
|
NCBI chr 8:10,927,188...10,954,442
|
|
G |
Casp2 |
caspase 2 |
affects expression |
EXP |
cadmium acetate affects the expression of CASP2 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 4:72,116,265...72,134,023
|
|
G |
Casp3 |
caspase 3 |
multiple interactions increases activity increases cleavage increases expression |
EXP ISO |
2-aminoethoxydiphenylborane inhibits the reaction [cadmium acetate results in increased cleavage of CASP3 protein]; Caspase Inhibitors inhibits the reaction [cadmium acetate results in increased expression of CASP3 protein modified form]; KN 93 inhibits the reaction [cadmium acetate results in increased cleavage of CASP3 protein]; puerarin inhibits the reaction [cadmium acetate results in increased activity of CASP3 protein]; pyrazolanthrone inhibits the reaction [cadmium acetate results in increased cleavage of CASP3 protein]; Thioctic Acid inhibits the reaction [cadmium acetate results in increased expression of CASP3 protein modified form]; U 0126 inhibits the reaction [cadmium acetate results in increased cleavage of CASP3 protein] Acetylcysteine inhibits the reaction [cadmium acetate results in increased activity of CASP3 protein]; isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone analog inhibits the reaction [cadmium acetate results in increased activity of CASP3 protein] |
CTD |
PMID:15450950 PMID:16169029 PMID:24577723 PMID:25043952 PMID:27717697 PMID:29883672 PMID:30605698 More...
|
|
NCBI chr16:52,395,539...52,413,794
|
|
G |
Casp6 |
caspase 6 |
affects expression |
EXP |
cadmium acetate affects the expression of CASP6 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 2:221,140,287...221,152,727
|
|
G |
Casp8 |
caspase 8 |
multiple interactions increases activity |
ISO |
Acetylcysteine inhibits the reaction [cadmium acetate results in increased activity of CASP8 protein]; CASP8 affects the reaction [cadmium acetate results in increased cleavage of BID protein] |
CTD |
PMID:15450950 PMID:16169029 |
|
NCBI chr 9:67,747,109...67,806,699
|
|
G |
Casp9 |
caspase 9 |
multiple interactions increases expression increases activity |
ISO EXP |
Acetylcysteine inhibits the reaction [cadmium acetate results in increased activity of CASP9 protein] Thioctic Acid inhibits the reaction [cadmium acetate results in increased expression of CASP9 protein modified form] |
CTD |
PMID:15450950 PMID:16169029 PMID:30605698 |
|
|
|
G |
Cat |
catalase |
increases expression increases activity affects expression multiple interactions decreases activity |
EXP |
cadmium acetate results in increased expression of CAT protein cadmium acetate results in increased activity of CAT protein cadmium acetate affects the expression of CAT mRNA [cadmium acetate co-treated with lead acetate] results in increased activity of CAT protein; puerarin inhibits the reaction [cadmium acetate results in increased activity of CAT protein]; Trehalose inhibits the reaction [cadmium acetate results in increased expression of CAT protein] cadmium acetate results in decreased activity of CAT protein |
CTD |
PMID:16249259 PMID:16897041 PMID:21182167 PMID:23534466 PMID:29140578 PMID:34897960 More...
|
|
NCBI chr 3:110,297,340...110,329,526
|
|
G |
Ccnb1 |
cyclin B1 |
affects expression |
EXP |
cadmium acetate affects the expression of CCNB1 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 2:33,646,252...33,655,225
|
|
G |
Ccne1 |
cyclin E1 |
multiple interactions |
ISO |
cadmium acetate results in decreased activity of [CCNE1 protein binds to CDK1 protein] |
CTD |
PMID:20839231 |
|
NCBI chr 1:99,918,672...99,927,986
|
|
G |
Cct3 |
chaperonin containing TCP1 subunit 3 |
decreases expression |
ISO |
cadmium acetate results in decreased expression of CCT3 mRNA |
CTD |
PMID:18155341 |
|
NCBI chr 2:173,765,701...173,790,353
|
|
G |
Cd46 |
CD46 molecule |
decreases expression |
ISO |
cadmium acetate results in decreased expression of CD46 mRNA |
CTD |
PMID:18155341 |
|
NCBI chr13:109,104,122...109,134,903
|
|
G |
Cdc42 |
cell division cycle 42 |
affects expression |
EXP |
cadmium acetate affects the expression of CDC42 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 5:154,838,478...154,876,629
|
|
G |
Cdk1 |
cyclin-dependent kinase 1 |
decreases expression multiple interactions |
ISO |
cadmium acetate results in decreased expression of CDK1 mRNA; cadmium acetate results in decreased expression of CDK1 protein cadmium acetate promotes the reaction [CDKN1A protein binds to CDK1 protein]; cadmium acetate results in decreased activity of [CCNE1 protein binds to CDK1 protein] |
CTD |
PMID:20839231 |
|
NCBI chr20:19,265,252...19,280,456
|
|
G |
Cdk4 |
cyclin-dependent kinase 4 |
affects expression |
EXP |
cadmium acetate affects the expression of CDK4 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 7:64,771,453...64,774,891
|
|
G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
decreases expression multiple interactions increases expression |
ISO |
cadmium acetate results in decreased expression of CDKN1A protein cadmium acetate promotes the reaction [CDKN1A protein binds to CDK1 protein] cadmium acetate results in increased expression of CDKN1A mRNA; cadmium acetate results in increased expression of CDKN1A protein |
CTD |
PMID:12965115 PMID:15450950 PMID:20839231 |
|
NCBI chr20:7,150,820...7,161,373
|
|
G |
Cox4i1 |
cytochrome c oxidase subunit 4i1 |
affects expression |
EXP |
cadmium acetate affects the expression of COX4I1 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr19:65,630,383...65,636,623
|
|
G |
Cox5a |
cytochrome c oxidase subunit 5A |
affects expression |
EXP |
cadmium acetate affects the expression of COX5A mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 8:66,818,284...66,829,691
|
|
G |
Cox5b |
cytochrome c oxidase subunit 5B |
affects expression |
EXP |
cadmium acetate affects the expression of COX5B mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 9:38,921,980...38,923,806
|
|
G |
Cox6a1 |
cytochrome c oxidase subunit 6A1 |
affects expression |
EXP |
cadmium acetate affects the expression of COX6A1 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr12:41,261,983...41,265,037
|
|
G |
Cox6a2 |
cytochrome c oxidase subunit 6A2 |
affects expression |
EXP |
cadmium acetate affects the expression of COX6A2 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 1:192,218,970...192,221,188
|
|
G |
Cox7a2 |
cytochrome c oxidase subunit 7A2 |
affects expression |
EXP |
cadmium acetate affects the expression of COX7A2 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 8:80,716,824...80,720,922
|
|
G |
Cox8a |
cytochrome c oxidase subunit 8A |
affects expression |
EXP |
cadmium acetate affects the expression of COX8A mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 1:213,831,302...213,833,623
|
|
G |
Creg1 |
cellular repressor of E1A-stimulated genes 1 |
decreases expression |
ISO |
cadmium acetate results in decreased expression of CREG1 mRNA |
CTD |
PMID:18155341 |
|
NCBI chr13:80,552,779...80,565,272
|
|
G |
Cryab |
crystallin, alpha B |
affects expression |
EXP |
cadmium acetate affects the expression of CRYAB mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 8:59,989,885...59,995,532
|
|
G |
Cryz |
crystallin zeta |
affects expression |
EXP |
cadmium acetate affects the expression of CRYZ mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 2:246,211,707...246,239,472
|
|
G |
Ctsk |
cathepsin K |
multiple interactions increases expression decreases expression |
EXP |
puerarin inhibits the reaction [cadmium acetate results in decreased expression of CTSK protein]; puerarin inhibits the reaction [cadmium acetate results in increased expression of CTSK mRNA] |
CTD |
PMID:34897960 |
|
NCBI chr 2:185,747,548...185,758,512
|
|
G |
Cyp11a1 |
cytochrome P450, family 11, subfamily a, polypeptide 1 |
decreases expression multiple interactions |
EXP |
cadmium acetate results in decreased expression of CYP11A1 mRNA [cadmium acetate co-treated with lead acetate] results in decreased expression of CYP11A1 mRNA |
CTD |
PMID:21182167 |
|
NCBI chr 8:67,318,665...67,330,196
|
|
G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
affects expression |
EXP |
cadmium acetate affects the expression of CYP1A1 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 8:66,991,940...66,998,014
|
|
G |
Cyp2c11 |
cytochrome P450, subfamily 2, polypeptide 11 |
affects expression |
EXP |
cadmium acetate affects the expression of CYP2C11 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 1:246,175,216...246,211,445
|
|
G |
Cyp2c12 |
cytochrome P450, family 2, subfamily c, polypeptide 12 |
affects expression |
EXP |
cadmium acetate affects the expression of CYP2C12 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 1:238,699,859...238,757,011
|
|
G |
Cyp3a23-3a1 |
cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 |
affects expression |
EXP |
cadmium acetate affects the expression of CYP3A23-3A1 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr12:14,369,950...14,398,803
|
|
G |
Cyp4f4 |
cytochrome P450, family 4, subfamily f, polypeptide 4 |
affects expression |
EXP |
cadmium acetate affects the expression of CYP4F4 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 7:11,717,208...11,733,507
|
|
G |
Cyp51 |
cytochrome P450, family 51 |
affects expression |
EXP |
cadmium acetate affects the expression of CYP51 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 4:30,036,956...30,055,410
|
|
G |
Dad1 |
defender against cell death 1 |
affects expression |
EXP |
cadmium acetate affects the expression of DAD1 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr15:27,677,286...27,697,120
|
|
G |
Dao |
D-amino-acid oxidase |
affects expression |
EXP |
cadmium acetate affects the expression of DAO mRNA |
CTD |
PMID:16249259 |
|
NCBI chr12:42,592,342...42,613,046
|
|
G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression multiple interactions |
EXP |
cadmium acetate results in increased expression of DDIT3 protein Chloroquine promotes the reaction [cadmium acetate results in increased expression of DDIT3 protein]; KN 93 inhibits the reaction [cadmium acetate results in increased expression of DDIT3 protein]; salubrinal inhibits the reaction [cadmium acetate results in increased expression of DDIT3 protein]; Sirolimus inhibits the reaction [cadmium acetate results in increased expression of DDIT3 protein]; Thioctic Acid inhibits the reaction [cadmium acetate results in increased expression of DDIT3 protein]; U 0126 promotes the reaction [cadmium acetate results in increased expression of DDIT3 protein] |
CTD |
PMID:29870746 PMID:29883672 PMID:30605698 |
|
NCBI chr 7:65,001,695...65,006,517
|
|
G |
Decr1 |
2,4-dienoyl-CoA reductase 1 |
affects expression |
EXP |
cadmium acetate affects the expression of DECR1 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 5:29,411,172...29,439,054
|
|
G |
Dnaja1 |
DnaJ heat shock protein family (Hsp40) member A1 |
affects expression |
EXP |
cadmium acetate affects the expression of DNAJA1 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 5:55,842,414...55,853,326
|
|
G |
Dnajb1 |
DnaJ heat shock protein family (Hsp40) member B1 |
increases expression |
ISO |
cadmium acetate results in increased expression of DNAJB1 mRNA |
CTD |
PMID:18155341 |
|
NCBI chr19:41,427,453...41,431,141
|
|
G |
Dut |
deoxyuridine triphosphatase |
affects expression |
EXP |
cadmium acetate affects the expression of DUT mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 3:112,498,864...112,509,994
|
|
G |
E2f1 |
E2F transcription factor 1 |
affects localization decreases activity decreases expression multiple interactions |
ISO |
cadmium acetate affects the localization of E2F1 protein cadmium acetate results in decreased activity of E2F1 protein cadmium acetate results in decreased expression of E2F1 mRNA cadmium acetate promotes the reaction [RB1 protein modified form binds to E2F1 protein] |
CTD |
PMID:18155341 PMID:20839231 |
|
NCBI chr 3:163,524,739...163,535,563
|
|
G |
Eef1a1 |
eukaryotic translation elongation factor 1 alpha 1 |
increases expression |
ISO |
cadmium acetate results in increased expression of EEF1A1 mRNA |
CTD |
PMID:12965115 |
|
NCBI chr 8:79,341,554...79,344,784
|
|
G |
Eif2s1 |
eukaryotic translation initiation factor 2 subunit alpha |
increases expression increases phosphorylation multiple interactions |
EXP |
cadmium acetate results in increased expression of EIF2S1 protein modified form cadmium acetate results in increased phosphorylation of EIF2S1 protein salubrinal inhibits the reaction [cadmium acetate results in increased expression of EIF2S1 protein modified form]; Sirolimus inhibits the reaction [cadmium acetate results in increased phosphorylation of EIF2S1 protein]; Thioctic Acid inhibits the reaction [cadmium acetate results in increased expression of EIF2S1 protein modified form]; U 0126 promotes the reaction [cadmium acetate results in increased phosphorylation of EIF2S1 protein] |
CTD |
PMID:29870746 PMID:30605698 |
|
NCBI chr 6:103,405,880...103,430,549
|
|
G |
Endog |
endonuclease G |
affects localization multiple interactions |
EXP |
cadmium acetate affects the localization of ENDOG protein pyrazolanthrone inhibits the reaction [cadmium acetate affects the localization of ENDOG protein]; U 0126 inhibits the reaction [cadmium acetate affects the localization of ENDOG protein] |
CTD |
PMID:24577723 |
|
NCBI chr 3:13,449,113...13,451,715
|
|
G |
Eno1 |
enolase 1 |
increases expression decreases expression |
ISO |
cadmium acetate results in increased expression of ENO1 mRNA cadmium acetate results in decreased expression of ENO1 mRNA |
CTD |
PMID:12965115 PMID:18155341 |
|
NCBI chr 5:160,719,951...160,731,337
|
|
G |
Ephx1 |
epoxide hydrolase 1 |
affects expression |
EXP |
cadmium acetate affects the expression of EPHX1 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr13:95,246,079...95,275,852
|
|
G |
Ephx2 |
epoxide hydrolase 2 |
affects expression |
EXP |
cadmium acetate affects the expression of EPHX2 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr15:40,289,901...40,327,632
|
|
G |
Fas |
Fas cell surface death receptor |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of FAS protein] |
CTD |
PMID:16169029 |
|
NCBI chr 1:241,212,155...241,245,774
|
|
G |
Fbln1 |
fibulin 1 |
decreases expression |
ISO |
cadmium acetate results in decreased expression of FBLN1 mRNA |
CTD |
PMID:18155341 |
|
NCBI chr 7:116,310,582...116,390,075
|
|
G |
Fosb |
FosB proto-oncogene, AP-1 transcription factor subunit |
increases expression |
ISO |
cadmium acetate results in increased expression of FOSB mRNA |
CTD |
PMID:18155341 |
|
NCBI chr 1:88,082,324...88,089,506
|
|
G |
Fosl2 |
FOS like 2, AP-1 transcription factor subunit |
affects expression |
EXP |
cadmium acetate affects the expression of FOSL2 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 6:30,017,952...30,039,269
|
|
G |
Ftl1 |
ferritin light chain 1 |
increases expression |
ISO |
cadmium acetate results in increased expression of FTL mRNA |
CTD |
PMID:12965115 |
|
NCBI chr 1:105,072,858...105,074,705
|
|
G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
affects expression |
EXP |
cadmium acetate affects the expression of GADD45A mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 4:97,484,497...97,486,799
|
|
G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
increases expression multiple interactions |
EXP |
cadmium acetate results in increased expression of GCLC protein Trehalose inhibits the reaction [cadmium acetate results in increased expression of GCLC protein] |
CTD |
PMID:29140578 |
|
NCBI chr 8:87,510,251...87,548,896
|
|
G |
Gclm |
glutamate cysteine ligase, modifier subunit |
multiple interactions increases expression |
EXP |
Trehalose inhibits the reaction [cadmium acetate results in increased expression of GCLM protein] |
CTD |
PMID:29140578 |
|
NCBI chr 2:213,032,135...213,052,192
|
|
G |
Gpi |
glucose-6-phosphate isomerase |
multiple interactions |
EXP |
[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of GPI mRNA; puerarin inhibits the reaction [[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of GPI mRNA] |
CTD |
PMID:33404196 |
|
NCBI chr 1:86,828,211...86,856,077
|
|
G |
Gpt |
glutamic--pyruvic transaminase |
increases expression |
ISO |
cadmium acetate results in increased expression of GPT protein |
CTD |
PMID:37128655 |
|
NCBI chr 7:110,295,599...110,300,134
|
|
G |
Gpx1 |
glutathione peroxidase 1 |
multiple interactions increases expression |
EXP |
Trehalose inhibits the reaction [cadmium acetate results in increased expression of GPX1 protein] |
CTD |
PMID:29140578 |
|
NCBI chr 8:117,905,462...117,906,588
|
|
G |
Gsdmd |
gasdermin D |
multiple interactions increases expression |
EXP |
Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of GSDMD protein] |
CTD |
PMID:36347317 |
|
NCBI chr 7:109,423,209...109,427,771
|
|
G |
Gsr |
glutathione-disulfide reductase |
increases expression decreases activity affects expression multiple interactions |
EXP |
cadmium acetate results in increased expression of GSR protein cadmium acetate results in decreased activity of GSR protein cadmium acetate affects the expression of GSR mRNA Trehalose inhibits the reaction [cadmium acetate results in increased expression of GSR protein] |
CTD |
PMID:16249259 PMID:21182167 PMID:29140578 |
|
NCBI chr16:65,185,574...65,228,742
|
|
G |
Gsta3 |
glutathione S-transferase alpha 3 |
affects expression |
EXP |
cadmium acetate affects the expression of GSTA3 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 9:23,658,574...23,684,240
|
|
G |
Gstm1 |
glutathione S-transferase mu 1 |
affects expression |
EXP |
cadmium acetate affects the expression of GSTM1 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 2:198,338,005...198,346,007
|
|
G |
Hk1 |
hexokinase 1 |
multiple interactions |
EXP |
[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of HK1 mRNA; puerarin inhibits the reaction [[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of HK1 mRNA] |
CTD |
PMID:33404196 |
|
NCBI chr20:30,773,222...30,874,814
|
|
G |
Hmox1 |
heme oxygenase 1 |
increases expression multiple interactions |
EXP ISO |
cadmium acetate results in increased expression of HMOX1 protein cadmium acetate results in increased expression of HMOX1 mRNA; cadmium acetate results in increased expression of HMOX1 protein Trehalose inhibits the reaction [cadmium acetate results in increased expression of HMOX1 protein] Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of HMOX1 protein]; cadmium acetate results in increased expression of and affects the localization of HMOX1 protein |
CTD |
PMID:12965115 PMID:18155341 PMID:21787718 PMID:27427241 PMID:29140578 |
|
NCBI chr19:13,452,365...13,479,823
|
|
G |
Hmox2 |
heme oxygenase 2 |
affects expression |
EXP |
cadmium acetate affects the expression of HMOX2 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr10:10,797,076...10,831,178
|
|
G |
Hsp90aa1 |
heat shock protein 90 alpha family class A member 1 |
affects expression |
EXP |
cadmium acetate affects the expression of HSP90AA1 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 6:135,523,604...135,529,687
|
|
G |
Hspa1a |
heat shock protein family A (Hsp70) member 1A |
affects expression |
EXP |
cadmium acetate affects the expression of HSPA1A mRNA |
CTD |
PMID:16249259 |
|
NCBI chr20:3,875,411...3,877,866
|
|
G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
increases expression multiple interactions |
EXP |
cadmium acetate results in increased expression of HSPA5 protein Chloroquine promotes the reaction [cadmium acetate results in increased expression of HSPA5 protein]; KN 93 inhibits the reaction [cadmium acetate results in increased expression of HSPA5 protein]; Sirolimus inhibits the reaction [cadmium acetate results in increased expression of HSPA5 protein]; Thioctic Acid inhibits the reaction [cadmium acetate results in increased expression of HSPA5 protein]; U 0126 promotes the reaction [cadmium acetate results in increased expression of HSPA5 protein] |
CTD |
PMID:29870746 PMID:29883672 PMID:30605698 |
|
NCBI chr 3:38,453,016...38,457,475
|
|
G |
Hspa8 |
heat shock protein family A (Hsp70) member 8 |
affects expression |
EXP |
cadmium acetate affects the expression of HSPA8 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 8:50,080,514...50,084,376
|
|
G |
Hspb1 |
heat shock protein family B (small) member 1 |
affects expression |
EXP |
cadmium acetate affects the expression of HSPB1 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr12:26,430,640...26,432,301
|
|
G |
Hspb2 |
heat shock protein family B (small) member 2 |
affects expression |
EXP |
cadmium acetate affects the expression of HSPB2 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 8:59,989,640...59,991,215
|
|
G |
Ifng |
interferon gamma |
decreases secretion |
ISO |
cadmium acetate results in decreased secretion of IFNG protein |
CTD |
PMID:16510232 |
|
NCBI chr 7:55,789,180...55,793,216
|
|
G |
Ifngr2 |
interferon gamma receptor 2 |
decreases expression |
ISO |
cadmium acetate results in decreased expression of IFNGR2 mRNA |
CTD |
PMID:18155341 |
|
NCBI chr11:44,265,703...44,283,975
|
|
G |
Il10 |
interleukin 10 |
decreases secretion increases expression |
ISO |
cadmium acetate results in decreased secretion of IL10 protein cadmium acetate results in increased expression of IL10 mRNA |
CTD |
PMID:16510232 PMID:27427241 |
|
NCBI chr13:45,024,921...45,029,586
|
|
G |
Il1b |
interleukin 1 beta |
increases secretion multiple interactions increases cleavage decreases secretion |
EXP ISO |
cadmium acetate results in increased secretion of IL1B protein Acetylcysteine inhibits the reaction [cadmium acetate results in increased cleavage of IL1B protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased secretion of IL1B protein] cadmium acetate results in decreased secretion of IL1B protein |
CTD |
PMID:16510232 PMID:36347317 |
|
NCBI chr 3:137,030,200...137,036,581
|
|
G |
Il1r2 |
interleukin 1 receptor type 2 |
affects expression |
EXP |
cadmium acetate affects the expression of IL1R2 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 9:42,384,280...42,424,726
|
|
G |
Il6 |
interleukin 6 |
increases secretion multiple interactions increases expression |
ISO |
cadmium acetate results in increased secretion of IL6 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [cadmium acetate results in increased secretion of IL6 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [cadmium acetate results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased secretion of IL6 protein]; pyrazolanthrone promotes the reaction [cadmium acetate results in increased secretion of IL6 protein]; RELA protein affects the reaction [cadmium acetate results in increased secretion of IL6 protein]; Thiourea inhibits the reaction [cadmium acetate results in increased secretion of IL6 protein] cadmium acetate results in increased expression of IL6 mRNA |
CTD |
PMID:27427241 |
|
NCBI chr 4:5,889,999...5,894,575
|
|
G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
affects expression |
EXP |
cadmium acetate affects the expression of JUN mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 5:115,009,900...115,012,993
|
|
G |
Junb |
JunB proto-oncogene, AP-1 transcription factor subunit |
affects expression |
EXP |
cadmium acetate affects the expression of JUNB mRNA |
CTD |
PMID:16249259 |
|
NCBI chr19:23,176,265...23,178,049
|
|
G |
Kalrn |
kalirin, RhoGEF kinase |
decreases expression |
ISO |
cadmium acetate results in decreased expression of KALRN mRNA |
CTD |
PMID:18155341 |
|
NCBI chr11:79,703,345...80,309,210
|
|
G |
Keap1 |
Kelch-like ECH-associated protein 1 |
decreases expression multiple interactions |
EXP |
cadmium acetate results in decreased expression of KEAP1 protein Trehalose inhibits the reaction [cadmium acetate results in decreased expression of KEAP1 protein] |
CTD |
PMID:29140578 |
|
NCBI chr 8:19,768,375...19,777,862
|
|
G |
Lamp1 |
lysosomal-associated membrane protein 1 |
multiple interactions |
EXP |
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [cadmium acetate affects the localization of [LAMP1 protein co-treated with MAP1LC3B protein]]; 2-aminoethoxydiphenyl borate inhibits the reaction [cadmium acetate affects the localization of [LAMP1 protein co-treated with MAP1LC3B protein]]; Acetylcysteine inhibits the reaction [cadmium acetate affects the localization of [LAMP1 protein co-treated with MAP1LC3B protein]]; cadmium acetate affects the localization of [LAMP1 protein co-treated with MAP1LC3B protein]; Thapsigargin promotes the reaction [cadmium acetate affects the localization of [LAMP1 protein co-treated with MAP1LC3B protein]] |
CTD |
PMID:28347754 |
|
NCBI chr16:83,058,131...83,082,843
|
|
G |
Lamtor1 |
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 |
decreases expression multiple interactions |
EXP |
cadmium acetate results in decreased expression of LAMTOR1 protein puerarin promotes the reaction [cadmium acetate results in decreased expression of LAMTOR1 protein] |
CTD |
PMID:34897960 |
|
NCBI chr 1:165,684,001...165,689,698
|
|
G |
Ldha |
lactate dehydrogenase A |
multiple interactions |
EXP |
[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of LDHA protein; puerarin inhibits the reaction [[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of LDHA protein] |
CTD |
PMID:33404196 |
|
NCBI chr 1:97,371,823...97,381,247
|
|
G |
Lta |
lymphotoxin alpha |
affects expression |
EXP |
cadmium acetate affects the expression of LTA mRNA |
CTD |
PMID:16249259 |
|
NCBI chr20:3,622,291...3,625,852
|
|
G |
Mad2l1 |
mitotic arrest deficient 2 like 1 |
decreases expression |
ISO |
cadmium acetate results in decreased expression of MAD2L1 mRNA |
CTD |
PMID:18155341 |
|
NCBI chr 4:97,236,419...97,247,603
|
|
G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
multiple interactions decreases expression |
EXP |
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [cadmium acetate affects the localization of [LAMP1 protein co-treated with MAP1LC3B protein]]; 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [cadmium acetate affects the localization of [RAB7A protein co-treated with MAP1LC3B protein]]; 2-aminoethoxydiphenyl borate inhibits the reaction [cadmium acetate affects the localization of [LAMP1 protein co-treated with MAP1LC3B protein]]; 2-aminoethoxydiphenyl borate inhibits the reaction [cadmium acetate affects the localization of [RAB7A protein co-treated with MAP1LC3B protein]]; Acetylcysteine inhibits the reaction [cadmium acetate affects the localization of [LAMP1 protein co-treated with MAP1LC3B protein]]; Acetylcysteine inhibits the reaction [cadmium acetate affects the localization of [RAB7A protein co-treated with MAP1LC3B protein]]; cadmium acetate affects the localization of [LAMP1 protein co-treated with MAP1LC3B protein]; cadmium acetate affects the localization of [RAB7A protein co-treated with MAP1LC3B protein]; puerarin inhibits the reaction [cadmium acetate results in decreased expression of MAP1LC3B protein modified form]; Thapsigargin promotes the reaction [cadmium acetate affects the localization of [LAMP1 protein co-treated with MAP1LC3B protein]]; Thapsigargin promotes the reaction [cadmium acetate affects the localization of [RAB7A protein co-treated with MAP1LC3B protein]] |
CTD |
PMID:28347754 PMID:34897960 |
|
NCBI chr19:66,571,631...66,582,270
|
|
G |
Map2k1 |
mitogen activated protein kinase kinase 1 |
affects expression |
EXP |
cadmium acetate affects the expression of MAP2K1 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 8:73,578,747...73,650,184
|
|
G |
Map2k2 |
mitogen activated protein kinase kinase 2 |
affects expression |
EXP |
cadmium acetate affects the expression of MAP2K2 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 7:9,241,449...9,264,216
|
|
G |
Map2k5 |
mitogen activated protein kinase kinase 5 |
increases expression affects expression |
ISO EXP |
cadmium acetate results in increased expression of MAP2K5 mRNA cadmium acetate affects the expression of MAP2K5 mRNA |
CTD |
PMID:12965115 PMID:16249259 |
|
NCBI chr 8:72,520,616...72,748,395
|
|
G |
Map3k1 |
mitogen-activated protein kinase kinase kinase 1 |
affects expression |
EXP |
cadmium acetate affects the expression of MAP3K1 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 2:45,081,889...45,150,555
|
|
G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions increases phosphorylation affects expression |
EXP |
KN 93 inhibits the reaction [cadmium acetate results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [cadmium acetate results in increased phosphorylation of MAPK1 protein] cadmium acetate affects the expression of MAPK1 mRNA |
CTD |
PMID:15925026 PMID:16249259 PMID:24577723 PMID:25043952 PMID:29870746 PMID:29883672 More...
|
|
NCBI chr11:97,462,025...97,529,193
|
|
G |
Mapk14 |
mitogen activated protein kinase 14 |
affects expression increases phosphorylation multiple interactions |
EXP |
cadmium acetate affects the expression of MAPK14 mRNA cadmium acetate results in increased phosphorylation of MAPK14 protein bisindolylmaleimide I inhibits the reaction [cadmium acetate results in increased phosphorylation of MAPK14 protein] |
CTD |
PMID:15925026 PMID:16249259 PMID:29870746 |
|
NCBI chr20:6,751,288...6,812,294
|
|
G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions increases phosphorylation |
EXP |
KN 93 inhibits the reaction [cadmium acetate results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [cadmium acetate results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:15925026 PMID:24577723 PMID:25043952 PMID:29870746 PMID:29883672 |
|
NCBI chr 1:190,797,189...190,803,411
|
|
G |
Mapk6 |
mitogen-activated protein kinase 6 |
affects expression |
EXP |
cadmium acetate affects the expression of MAPK6 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 8:85,027,141...85,050,236
|
|
G |
Mapk8 |
mitogen-activated protein kinase 8 |
increases phosphorylation |
EXP |
cadmium acetate results in increased phosphorylation of MAPK8 protein |
CTD |
PMID:15925026 |
|
NCBI chr16:8,645,171...8,728,225
|
|
G |
Mdm2 |
MDM2 proto-oncogene |
increases expression |
ISO |
cadmium acetate results in increased expression of MDM2 protein |
CTD |
PMID:15450950 |
|
NCBI chr 7:55,176,558...55,201,757
|
|
G |
Mif |
macrophage migration inhibitory factor |
increases expression |
ISO |
cadmium acetate results in increased expression of MIF mRNA |
CTD |
PMID:12965115 |
|
NCBI chr20:12,790,919...12,791,784
|
|
G |
Mta1 |
metastasis associated 1 |
increases expression |
ISO |
cadmium acetate results in increased expression of MTA1 mRNA |
CTD |
PMID:18155341 |
|
NCBI chr 6:137,999,845...138,038,696
|
|
G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
affects expression |
EXP |
cadmium acetate affects the expression of MYC mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 7:95,483,105...95,488,031
|
|
G |
Naa80 |
N(alpha)-acetyltransferase 80, NatH catalytic subunit |
increases expression |
ISO |
cadmium acetate results in increased expression of NAA80 mRNA |
CTD |
PMID:12965115 |
|
NCBI chr 8:108,254,314...108,257,564
|
|
G |
Ncl |
nucleolin |
decreases expression |
ISO |
cadmium acetate results in decreased expression of NCL mRNA |
CTD |
PMID:18155341 |
|
NCBI chr 9:94,447,559...94,456,083
|
|
G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of NFE2L2 protein]; cadmium acetate results in increased expression of and affects the localization of NFE2L2 protein |
CTD |
PMID:21787718 |
|
NCBI chr 3:81,001,529...81,031,165
|
|
G |
Ngf |
nerve growth factor |
multiple interactions |
EXP |
cadmium acetate inhibits the reaction [NGF protein results in increased uptake of Calcium] |
CTD |
PMID:1374475 |
|
NCBI chr 2:192,589,580...192,642,971
|
|
G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
multiple interactions increases expression |
EXP |
Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of NLRP3 protein] |
CTD |
PMID:36347317 |
|
NCBI chr10:44,826,299...44,853,373
|
|
G |
Nmt1 |
N-myristoyltransferase 1 |
decreases expression |
ISO |
cadmium acetate results in decreased expression of NMT1 mRNA |
CTD |
PMID:18155341 |
|
NCBI chr10:87,988,826...88,025,405
|
|
G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
increases expression multiple interactions |
EXP |
cadmium acetate results in increased expression of NQO1 protein Trehalose inhibits the reaction [cadmium acetate results in increased expression of NQO1 protein] |
CTD |
PMID:29140578 |
|
NCBI chr19:52,205,374...52,220,267
|
|
G |
Nr4a1 |
nuclear receptor subfamily 4, group A, member 1 |
multiple interactions increases expression |
ISO EXP |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [cadmium acetate results in increased expression of NR4A1 protein]; cadmium acetate results in increased expression of and results in increased activity of NR4A1 protein; Cyclosporine inhibits the reaction [cadmium acetate results in increased expression of NR4A1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [cadmium acetate results in increased expression of NR4A1 protein] cadmium acetate results in increased expression of NR4A1 mRNA; cadmium acetate results in increased expression of NR4A1 protein |
CTD |
PMID:15016657 |
|
NCBI chr 7:132,368,399...132,389,300
|
|
G |
Nr4a2 |
nuclear receptor subfamily 4, group A, member 2 |
increases expression |
ISO EXP |
cadmium acetate results in increased expression of NR4A2 mRNA |
CTD |
PMID:15016657 |
|
NCBI chr 3:41,689,847...41,707,036
|
|
G |
Nr4a3 |
nuclear receptor subfamily 4, group A, member 3 |
increases expression |
EXP ISO |
cadmium acetate results in increased expression of NR4A3 mRNA |
CTD |
PMID:12965115 PMID:15016657 |
|
NCBI chr 5:67,157,141...67,198,287
|
|
G |
Pabpc4 |
poly(A) binding protein, cytoplasmic 4 |
decreases expression |
ISO |
cadmium acetate results in decreased expression of PABPC4 mRNA |
CTD |
PMID:18155341 |
|
NCBI chr 5:135,563,142...135,578,985
|
|
G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
multiple interactions affects expression increases cleavage |
EXP ISO |
puerarin inhibits the reaction [cadmium acetate results in increased cleavage of PARP1 protein]; pyrazolanthrone inhibits the reaction [cadmium acetate results in increased cleavage of PARP1 protein]; U 0126 inhibits the reaction [cadmium acetate results in increased cleavage of PARP1 protein] cadmium acetate affects the expression of PARP1 mRNA |
CTD |
PMID:15450950 PMID:16249259 PMID:24577723 PMID:25043952 PMID:27717697 |
|
NCBI chr13:94,839,484...94,871,295
|
|
G |
Pfkp |
phosphofructokinase, platelet |
multiple interactions |
EXP |
[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of PFKP mRNA; puerarin inhibits the reaction [[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of PFKP mRNA] |
CTD |
PMID:33404196 |
|
NCBI chr17:68,639,749...68,704,055
|
|
G |
Pgam1 |
phosphoglycerate mutase 1 |
multiple interactions |
EXP |
[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of PGAM1 mRNA; puerarin inhibits the reaction [[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of PGAM1 mRNA] |
CTD |
PMID:33404196 |
|
NCBI chr 1:250,673,152...250,680,762
|
|
G |
Plp2 |
proteolipid protein 2 |
decreases expression |
ISO |
cadmium acetate results in decreased expression of PLP2 mRNA |
CTD |
PMID:18155341 |
|
NCBI chr X:14,834,249...14,837,648
|
|
G |
Pnkd |
PNKD metallo-beta-lactamase domain containing |
increases expression |
ISO |
cadmium acetate results in increased expression of PNKD mRNA |
CTD |
PMID:12965115 |
|
NCBI chr 9:75,868,620...75,937,126
|
|
G |
Pola1 |
DNA polymerase alpha 1, catalytic subunit |
decreases expression |
ISO |
cadmium acetate results in decreased expression of POLA1 mRNA |
CTD |
PMID:20839231 |
|
NCBI chr X:62,028,475...62,342,455
|
|
G |
Polb |
DNA polymerase beta |
affects expression |
EXP |
cadmium acetate affects the expression of POLB mRNA |
CTD |
PMID:16249259 |
|
NCBI chr16:69,379,438...69,402,710
|
|
G |
Por |
cytochrome p450 oxidoreductase |
affects expression |
EXP |
cadmium acetate affects the expression of POR mRNA |
CTD |
PMID:16249259 |
|
NCBI chr12:26,587,674...26,655,612
|
|
G |
Ppargc1a |
PPARG coactivator 1 alpha |
multiple interactions |
EXP |
[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of PPARGC1A protein; puerarin inhibits the reaction [[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of PPARGC1A protein] |
CTD |
PMID:33404196 |
|
NCBI chr14:63,073,505...63,729,215
|
|
G |
Prdx2 |
peroxiredoxin 2 |
affects expression |
EXP |
cadmium acetate affects the expression of PRDX2 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr19:23,180,927...23,186,217
|
|
G |
Prss23 |
serine protease 23 |
decreases expression |
ISO |
cadmium acetate results in decreased expression of PRSS23 mRNA |
CTD |
PMID:18155341 |
|
NCBI chr 1:143,402,725...143,422,182
|
|
G |
Ptbp1 |
polypyrimidine tract binding protein 1 |
increases expression |
ISO |
cadmium acetate results in increased expression of PTBP1 mRNA |
CTD |
PMID:12965115 |
|
NCBI chr 7:9,842,574...9,852,332
|
|
G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
increases expression |
ISO |
cadmium acetate results in increased expression of PTGS2 mRNA |
CTD |
PMID:12965115 |
|
NCBI chr13:64,714,063...64,722,320
|
|
G |
Rab7a |
RAB7A, member RAS oncogene family |
decreases expression multiple interactions |
EXP |
cadmium acetate results in decreased expression of RAB7A protein 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [cadmium acetate affects the localization of [RAB7A protein co-treated with MAP1LC3B protein]]; 2-aminoethoxydiphenyl borate inhibits the reaction [cadmium acetate affects the localization of [RAB7A protein co-treated with MAP1LC3B protein]]; Acetylcysteine inhibits the reaction [cadmium acetate affects the localization of [RAB7A protein co-treated with MAP1LC3B protein]]; cadmium acetate affects the localization of [RAB7A protein co-treated with MAP1LC3B protein]; Thapsigargin promotes the reaction [cadmium acetate affects the localization of [RAB7A protein co-treated with MAP1LC3B protein]] |
CTD |
PMID:28347754 PMID:34897960 |
|
NCBI chr 4:120,461,966...120,510,756
|
|
G |
Rad23b |
RAD23 homolog B, nucleotide excision repair protein |
decreases expression |
ISO |
cadmium acetate results in decreased expression of RAD23B mRNA |
CTD |
PMID:18155341 |
|
NCBI chr 5:70,090,232...70,128,340
|
|
G |
Rb1 |
RB transcriptional corepressor 1 |
multiple interactions decreases phosphorylation decreases expression |
ISO |
cadmium acetate promotes the reaction [RB1 protein modified form binds to E2F1 protein] cadmium acetate results in decreased phosphorylation of RB1 protein cadmium acetate results in decreased expression of RB1 mRNA |
CTD |
PMID:20839231 |
|
NCBI chr15:54,780,858...54,911,989
|
|
G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
RELA protein affects the reaction [cadmium acetate results in increased secretion of IL6 protein] |
CTD |
PMID:27427241 |
|
NCBI chr 1:212,354,336...212,364,815
|
|
G |
Rgs2 |
regulator of G-protein signaling 2 |
increases expression |
ISO |
cadmium acetate results in increased expression of RGS2 mRNA |
CTD |
PMID:18155341 |
|
NCBI chr13:58,350,063...58,352,666
|
|
G |
Rps6ka1 |
ribosomal protein S6 kinase A1 |
affects expression |
EXP |
cadmium acetate affects the expression of RPS6KA1 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 5:151,362,819...151,402,064
|
|
G |
RT1-CE5 |
RT1 class I, locus CE5 |
decreases expression |
ISO |
cadmium acetate results in decreased expression of HLA-F mRNA |
CTD |
PMID:18155341 |
|
NCBI chr20:3,403,418...3,479,476
|
|
G |
Runx2 |
RUNX family transcription factor 2 |
multiple interactions decreases expression |
EXP |
puerarin inhibits the reaction [cadmium acetate results in decreased expression of RUNX2 protein] |
CTD |
PMID:34897960 |
|
NCBI chr 9:23,661,278...23,990,248
|
|
G |
S100a6 |
S100 calcium binding protein A6 |
increases expression |
ISO |
cadmium acetate results in increased expression of S100A6 mRNA |
CTD |
PMID:12965115 |
|
NCBI chr 2:178,398,189...178,399,763
|
|
G |
Sirt1 |
sirtuin 1 |
multiple interactions |
EXP |
[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of SIRT1 protein; puerarin inhibits the reaction [[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of SIRT1 protein] |
CTD |
PMID:33404196 |
|
NCBI chr20:25,305,953...25,328,000
|
|
G |
Slc25a4 |
solute carrier family 25 member 4 |
increases expression multiple interactions |
EXP |
cadmium acetate results in increased expression of SLC25A4 mRNA; cadmium acetate results in increased expression of SLC25A4 protein puerarin inhibits the reaction [cadmium acetate results in increased expression of SLC25A4 mRNA]; puerarin inhibits the reaction [cadmium acetate results in increased expression of SLC25A4 protein] |
CTD |
PMID:27717697 |
|
NCBI chr16:46,072,935...46,076,730
|
|
G |
Slc25a5 |
solute carrier family 25 member 5 |
multiple interactions decreases expression |
EXP |
puerarin inhibits the reaction [cadmium acetate results in decreased expression of SLC25A5 mRNA]; puerarin inhibits the reaction [cadmium acetate results in decreased expression of SLC25A5 protein] cadmium acetate results in decreased expression of SLC25A5 mRNA; cadmium acetate results in decreased expression of SLC25A5 protein |
CTD |
PMID:27717697 |
|
NCBI chr X:120,897,616...120,900,683
|
|
G |
Slc2a1 |
solute carrier family 2 member 1 |
multiple interactions |
EXP |
[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of SLC2A1 protein; puerarin inhibits the reaction [[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of SLC2A1 protein] |
CTD |
PMID:33404196 |
|
NCBI chr 5:138,002,522...138,030,742
|
|
G |
Slc31a1 |
solute carrier family 31 member 1 |
decreases expression |
ISO |
cadmium acetate results in decreased expression of SLC31A1 mRNA |
CTD |
PMID:24132751 |
|
NCBI chr 5:75,814,744...75,844,241
|
|
G |
Sod1 |
superoxide dismutase 1 |
multiple interactions increases expression decreases activity |
EXP |
Trehalose inhibits the reaction [cadmium acetate results in increased expression of SOD1 protein] cadmium acetate results in decreased activity of SOD1 protein |
CTD |
PMID:21182167 PMID:29140578 |
|
NCBI chr11:42,942,742...42,948,399
|
|
G |
Sod2 |
superoxide dismutase 2 |
increases expression multiple interactions decreases activity |
EXP |
cadmium acetate results in increased expression of SOD2 protein Trehalose inhibits the reaction [cadmium acetate results in increased expression of SOD2 protein] cadmium acetate results in decreased activity of SOD2 protein |
CTD |
PMID:21182167 PMID:29140578 |
|
NCBI chr 1:50,043,323...50,050,168
|
|
G |
Sp1 |
Sp1 transcription factor |
decreases expression |
ISO |
cadmium acetate results in decreased expression of SP1 mRNA |
CTD |
PMID:24132751 |
|
NCBI chr 7:135,419,864...135,450,513
|
|
G |
Sqstm1 |
sequestosome 1 |
multiple interactions decreases expression increases expression |
EXP |
[Sirolimus co-treated with cadmium acetate] results in decreased expression of SQSTM1 mRNA; Chloroquine inhibits the reaction [cadmium acetate results in decreased expression of SQSTM1 protein]; puerarin promotes the reaction [cadmium acetate results in increased expression of SQSTM1 protein]; U 0126 inhibits the reaction [cadmium acetate results in decreased expression of SQSTM1 protein] |
CTD |
PMID:28347754 PMID:29870746 PMID:34897960 |
|
NCBI chr10:35,026,598...35,037,750
|
|
G |
Ssrp1 |
structure specific recognition protein 1 |
affects expression |
EXP |
cadmium acetate affects the expression of SSRP1 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 3:70,124,371...70,134,481
|
|
G |
Stac |
SH3 and cysteine rich domain |
increases expression |
ISO |
cadmium acetate results in increased expression of STAC mRNA |
CTD |
PMID:18155341 |
|
NCBI chr 8:111,530,800...111,653,228
|
|
G |
Star |
steroidogenic acute regulatory protein |
decreases expression |
EXP |
cadmium acetate results in decreased expression of STAR mRNA |
CTD |
PMID:21182167 |
|
NCBI chr16:72,969,824...72,974,447
|
|
G |
Stat5b |
signal transducer and activator of transcription 5B |
affects expression |
EXP |
cadmium acetate affects the expression of STAT5B mRNA |
CTD |
PMID:16249259 |
|
NCBI chr10:85,704,841...85,775,856
|
|
G |
Sult1a1 |
sulfotransferase family 1A member 1 |
affects expression |
EXP |
cadmium acetate affects the expression of SULT1A1 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 1:190,702,592...190,706,112
|
|
G |
Sult1c3 |
sulfotransferase family 1C member 3 |
affects expression |
EXP |
cadmium acetate affects the expression of SULT1C3 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 9:7,221,580...7,266,991
|
|
G |
Sult1e1 |
sulfotransferase family 1E member 1 |
affects expression |
EXP |
cadmium acetate affects the expression of SULT1E1 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr14:20,422,324...20,439,562
|
|
G |
Taf10 |
TATA-box binding protein associated factor 10 |
increases expression |
ISO |
cadmium acetate results in increased expression of TAF10 mRNA |
CTD |
PMID:12965115 |
|
NCBI chr 1:160,095,108...160,096,401
|
|
G |
Taok1 |
TAO kinase 1 |
affects expression |
EXP |
cadmium acetate affects the expression of TAOK1 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr10:62,871,198...62,989,049
|
|
G |
Tfeb |
transcription factor EB |
multiple interactions |
EXP |
cadmium acetate affects the localization of and results in decreased expression of TFEB protein |
CTD |
PMID:36347317 |
|
NCBI chr 9:20,696,440...20,752,265
|
|
G |
Tk1 |
thymidine kinase 1 |
decreases expression |
ISO |
cadmium acetate results in decreased expression of TK1 mRNA |
CTD |
PMID:20839231 |
|
NCBI chr10:103,533,449...103,544,818
|
|
G |
Tmsb4x |
thymosin beta 4, X-linked |
increases expression |
ISO |
cadmium acetate results in increased expression of TMSB4X mRNA |
CTD |
PMID:12965115 |
|
NCBI chr X:30,761,611...30,763,612
|
|
G |
Tnf |
tumor necrosis factor |
decreases secretion |
ISO |
cadmium acetate results in decreased secretion of TNF protein |
CTD |
PMID:16510232 |
|
NCBI chr20:3,626,685...3,629,303
|
|
G |
Tnfrsf11b |
TNF receptor superfamily member 11B |
increases expression multiple interactions |
EXP |
cadmium acetate results in increased expression of TNFRSF11B mRNA puerarin promotes the reaction [cadmium acetate results in increased expression of TNFRSF11B mRNA] |
CTD |
PMID:34897960 |
|
NCBI chr 7:87,456,318...87,484,324
|
|
G |
Tnfrsf1a |
TNF receptor superfamily member 1A |
affects expression |
EXP |
cadmium acetate affects the expression of TNFRSF1A mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 4:159,837,119...159,849,817
|
|
G |
Tnfsf11 |
TNF superfamily member 11 |
multiple interactions |
EXP |
[cadmium acetate co-treated with puerarin] results in increased expression of TNFSF11 mRNA |
CTD |
PMID:34897960 |
|
NCBI chr15:60,083,008...60,114,479
|
|
G |
Tp53 |
tumor protein p53 |
increases phosphorylation multiple interactions decreases expression |
ISO |
cadmium acetate results in increased phosphorylation of TP53 protein cadmium acetate results in increased degradation of and affects the localization of TP53 protein cadmium acetate results in decreased expression of TP53 mRNA |
CTD |
PMID:15450950 PMID:18155341 PMID:20839231 |
|
NCBI chr10:54,798,871...54,810,300
|
|
G |
Tpi1 |
triosephosphate isomerase 1 |
increases expression |
ISO |
cadmium acetate results in increased expression of TPI1 mRNA |
CTD |
PMID:12965115 |
|
NCBI chr 4:159,301,558...159,305,088
|
|
G |
Tubb5 |
tubulin, beta 5 class I |
decreases expression |
ISO |
cadmium acetate results in decreased expression of TUBB mRNA |
CTD |
PMID:18155341 |
|
NCBI chr20:2,917,577...2,921,726
|
|
G |
Ubl5 |
ubiquitin-like 5 |
increases expression |
ISO |
cadmium acetate results in increased expression of UBL5 mRNA |
CTD |
PMID:12965115 |
|
NCBI chr 8:19,181,504...19,185,224
|
|
G |
Ucp2 |
uncoupling protein 2 |
multiple interactions |
EXP |
[cadmium acetate results in increased abundance of Cadmium] which results in increased expression of UCP2 protein; puerarin inhibits the reaction [[cadmium acetate results in increased abundance of Cadmium] which results in increased expression of UCP2 protein] |
CTD |
PMID:33404196 |
|
NCBI chr 1:164,251,373...164,257,742
|
|
G |
Ugt1a6 |
UDP glucuronosyltransferase family 1 member A6 |
affects expression |
EXP |
cadmium acetate affects the expression of UGT1A6 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr 9:96,195,018...96,256,264
|
|
G |
Ugt2b1 |
UDP glucuronosyltransferase 2 family, polypeptide B1 |
affects expression |
EXP |
cadmium acetate affects the expression of UGT2B17 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr14:21,378,882...21,390,631
|
|
G |
Ugt2b15 |
UDP glucuronosyltransferase family 2 member B15 |
affects expression |
EXP |
cadmium acetate affects the expression of UGT2B15 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr14:20,768,015...20,783,599
|
|
G |
Ugt2b7 |
UDP glucuronosyltransferase family 2 member B7 |
affects expression |
EXP |
cadmium acetate affects the expression of UGT2B7 mRNA |
CTD |
PMID:16249259 |
|
NCBI chr14:21,251,535...21,274,451
|
|
G |
Vegfa |
vascular endothelial growth factor A |
increases expression |
ISO |
cadmium acetate results in increased expression of VEGFA mRNA |
CTD |
PMID:12965115 |
|
NCBI chr 9:22,452,854...22,468,194
|
|