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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cadmium acetate
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Accession:CHEBI:232796 term browser browse the term
Synonyms:exact_synonym: cadmium(2+);diacetate
 related_synonym: Formula=C2H3O2.C2H3O2.Cd;   InChI=1S/2C2H4O2.Cd/c2*1-2(3)4;/h2*1H3,(H,3,4);/q;;+2/p-2;   InChIKey=LHQLJMJLROMYRN-UHFFFAOYSA-L;   SMILES=CC(=O)[O-].CC(=O)[O-].[Cd+2]
 xref: CAS:543-90-8
 xref_mesh: MESH:C028031
 xref: PMID:37128655;   Wikipedia:https://en.wikipedia.org/wiki/Cadmium_acetate



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cadmium acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1b ATP-binding cassette, sub-family B member 1B affects expression EXP cadmium acetate affects the expression of ABCB1B mRNA CTD PMID:16249259 NCBI chr 4:26,197,706...26,280,156 JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 affects expression EXP cadmium acetate affects the expression of ABCC2 mRNA CTD PMID:16249259 NCBI chr 1:252,613,875...252,672,459 JBrowse link
G Acot2 acyl-CoA thioesterase 2 affects expression EXP cadmium acetate affects the expression of ACOT2 mRNA CTD PMID:16249259 NCBI chr 6:109,341,426...109,352,818 JBrowse link
G Actg2 actin gamma 2, smooth muscle decreases expression ISO cadmium acetate results in decreased expression of ACTG2 mRNA CTD PMID:18155341 NCBI chr 4:116,021,832...116,046,475 JBrowse link
G Agpat1 1-acylglycerol-3-phosphate O-acyltransferase 1 increases expression ISO cadmium acetate results in increased expression of AGPAT1 mRNA CTD PMID:12965115 NCBI chr20:4,135,955...4,144,880 JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 multiple interactions
affects localization
EXP pyrazolanthrone inhibits the reaction [cadmium acetate affects the localization of AIFM1 protein]; U 0126 inhibits the reaction [cadmium acetate affects the localization of AIFM1 protein] CTD PMID:24577723 PMID:25043952 NCBI chr  X:132,528,107...132,567,237 JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 multiple interactions
increases expression
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cadmium acetate results in increased expression of AKR1C3 protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of AKR1C3 protein]; Cycloheximide inhibits the reaction [cadmium acetate results in increased expression of AKR1C3 protein]
cadmium acetate results in increased expression of AKR1C3 mRNA; cadmium acetate results in increased expression of AKR1C3 protein
CTD PMID:21787718 NCBI chr17:71,020,884...71,037,779 JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
multiple interactions
increases oxidation
ISO cadmium acetate results in increased phosphorylation of AKT1 protein
Acetylcysteine inhibits the reaction [cadmium acetate results in decreased expression of AKT1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [cadmium acetate results in decreased expression of AKT1 protein]; cadmium acetate results in decreased expression of and results in decreased phosphorylation of AKT1 protein
cadmium acetate results in increased oxidation of AKT1 protein
Acetylcysteine inhibits the reaction [cadmium acetate results in increased phosphorylation of AKT1 protein]
CTD PMID:21787718 PMID:24933620 NCBI chr 6:137,534,810...137,555,131 JBrowse link
G Alad aminolevulinate dehydratase multiple interactions
increases activity
EXP [cadmium acetate results in increased activity of ALAD protein] which results in increased chemical synthesis of Porphobilinogen; cadmium acetate inhibits the reaction [Dithiothreitol results in increased activity of ALAD protein] CTD PMID:21360559 NCBI chr 5:75,961,993...75,972,334 JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 affects expression EXP cadmium acetate affects the expression of APEX1 mRNA CTD PMID:16249259 NCBI chr15:24,144,595...24,146,785 JBrowse link
G Atf4 activating transcription factor 4 multiple interactions
increases expression
EXP Chloroquine promotes the reaction [cadmium acetate results in increased expression of ATF4 protein]; KN 93 inhibits the reaction [cadmium acetate results in increased expression of ATF4 protein]; Sirolimus inhibits the reaction [cadmium acetate results in increased expression of ATF4 protein]; Thioctic Acid inhibits the reaction [cadmium acetate results in increased expression of ATF4 protein] CTD PMID:29870746 PMID:29883672 PMID:30605698 NCBI chr 7:113,684,681...113,686,739 JBrowse link
G Atg5 autophagy related 5 increases expression
multiple interactions
EXP cadmium acetate results in increased expression of ATG5 protein
[Sirolimus co-treated with cadmium acetate] results in increased expression of ATG5 mRNA; Chloroquine inhibits the reaction [cadmium acetate results in increased expression of ATG5 protein]
CTD PMID:29870746 NCBI chr20:49,380,835...49,471,826 JBrowse link
G B4galt2 beta-1,4-galactosyltransferase 2 increases expression ISO cadmium acetate results in increased expression of B4GALT2 mRNA CTD PMID:18155341 NCBI chr 5:131,412,541...131,422,573 JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases cleavage
multiple interactions
increases expression
ISO
EXP
cadmium acetate results in increased cleavage of BAX protein
2-aminoethoxydiphenylborane inhibits the reaction [cadmium acetate results in increased expression of BAX protein]; puerarin inhibits the reaction [cadmium acetate results in increased expression of BAX mRNA]; puerarin inhibits the reaction [cadmium acetate results in increased expression of BAX protein]; pyrazolanthrone inhibits the reaction [cadmium acetate results in increased expression of BAX protein]; salubrinal inhibits the reaction [cadmium acetate results in increased expression of BAX protein]; Thioctic Acid inhibits the reaction [cadmium acetate results in increased expression of BAX protein]; U 0126 inhibits the reaction [cadmium acetate results in increased expression of BAX protein]
cadmium acetate results in increased expression of BAX mRNA; cadmium acetate results in increased expression of BAX protein
Acetylcysteine inhibits the reaction [cadmium acetate results in increased cleavage of BAX protein]; CAPNS1 affects the reaction [cadmium acetate results in increased cleavage of BAX protein]
CTD PMID:12965115 PMID:16169029 PMID:24577723 PMID:25043952 PMID:27717697 More... NCBI chr 1:105,076,472...105,081,906 JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
decreases expression
multiple interactions
ISO
EXP
cadmium acetate results in increased expression of BCL2 protein
cadmium acetate results in decreased expression of BCL2 mRNA; cadmium acetate results in decreased expression of BCL2 protein
2-aminoethoxydiphenylborane inhibits the reaction [cadmium acetate results in decreased expression of BCL2 protein]; puerarin inhibits the reaction [cadmium acetate results in decreased expression of BCL2 mRNA]; puerarin inhibits the reaction [cadmium acetate results in decreased expression of BCL2 protein]; pyrazolanthrone inhibits the reaction [cadmium acetate results in decreased expression of BCL2 protein]; salubrinal inhibits the reaction [cadmium acetate results in decreased expression of BCL2 protein]; Thioctic Acid inhibits the reaction [cadmium acetate results in decreased expression of BCL2 protein]; U 0126 inhibits the reaction [cadmium acetate results in decreased expression of BCL2 protein]
CTD PMID:15450950 PMID:24577723 PMID:25043952 PMID:27717697 PMID:29883672 More... NCBI chr13:23,204,464...23,366,900 JBrowse link
G Bcl2l1 Bcl2-like 1 affects expression EXP cadmium acetate affects the expression of BCL2L1 mRNA CTD PMID:16249259 NCBI chr 3:161,713,777...161,764,844 JBrowse link
G Bcl6 BCL6, transcription repressor increases expression ISO cadmium acetate results in increased expression of BCL6 mRNA CTD PMID:18155341 NCBI chr11:76,854,090...76,877,389 JBrowse link
G Becn1 beclin 1 multiple interactions
increases expression
decreases expression
EXP [Sirolimus co-treated with cadmium acetate] results in increased expression of BECN1 mRNA; Chloroquine inhibits the reaction [cadmium acetate results in increased expression of BECN1 protein]; U 0126 inhibits the reaction [cadmium acetate results in increased expression of BECN1 protein]
cadmium acetate results in decreased expression of BECN1 protein
CTD PMID:29870746 PMID:34897960 NCBI chr10:86,731,649...86,747,002 JBrowse link
G Bid BH3 interacting domain death agonist increases cleavage
multiple interactions
ISO cadmium acetate results in increased cleavage of BID protein
Acetylcysteine inhibits the reaction [cadmium acetate results in increased cleavage of BID protein]; cadmium acetate results in increased cleavage of and results in increased localization of BID protein; CASP8 affects the reaction [cadmium acetate results in increased cleavage of BID protein]; isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone analog inhibits the reaction [cadmium acetate results in increased cleavage of BID protein]
CTD PMID:15450950 PMID:16169029 NCBI chr 4:155,785,366...155,808,775 JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A decreases expression ISO cadmium acetate results in decreased expression of BMPR1A mRNA CTD PMID:18155341 NCBI chr16:9,740,751...9,786,861 JBrowse link
G Capn1 calpain 1 increases expression
multiple interactions
EXP cadmium acetate results in increased expression of CAPN1 protein
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [cadmium acetate results in increased expression of CAPN1 protein]; 2-aminoethyl diphenylborinate inhibits the reaction [cadmium acetate results in increased expression of CAPN1 protein]; Thapsigargin promotes the reaction [cadmium acetate results in increased expression of CAPN1 protein]
CTD PMID:28347754 NCBI chr 1:212,705,219...212,736,134 JBrowse link
G Capns1 calpain, small subunit 1 increases expression
multiple interactions
increases cleavage
ISO cadmium acetate results in increased expression of CAPNS1 protein
cadmium acetate results in increased cleavage of and results in increased activity of CAPNS1 protein; CAPNS1 affects the reaction [cadmium acetate results in increased cleavage of BAX protein]
cadmium acetate results in increased cleavage of CAPNS1 protein
CTD PMID:15450950 PMID:16169029 NCBI chr 1:85,444,613...85,454,861 JBrowse link
G Casp1 caspase 1 increases cleavage
multiple interactions
EXP cadmium acetate results in increased cleavage of CASP1 protein
Acetylcysteine inhibits the reaction [cadmium acetate results in increased cleavage of CASP1 protein]
CTD PMID:36347317 NCBI chr 8:10,746,338...10,882,295 JBrowse link
G Casp12 caspase 12 increases expression
increases cleavage
multiple interactions
EXP cadmium acetate results in increased expression of CASP12 protein
cadmium acetate results in increased cleavage of CASP12 protein
2-aminoethoxydiphenylborane inhibits the reaction [cadmium acetate results in increased cleavage of CASP12 protein]; Caspase Inhibitors inhibits the reaction [cadmium acetate results in increased expression of CASP12 protein modified form]; Chloroquine promotes the reaction [cadmium acetate results in increased expression of CASP12 protein]; KN 93 inhibits the reaction [cadmium acetate results in increased cleavage of CASP12 protein]; Sirolimus inhibits the reaction [cadmium acetate results in increased expression of CASP12 protein]; U 0126 promotes the reaction [cadmium acetate results in increased expression of CASP12 protein]
CTD PMID:29870746 PMID:29883672 PMID:30605698 NCBI chr 8:10,927,188...10,954,442 JBrowse link
G Casp2 caspase 2 affects expression EXP cadmium acetate affects the expression of CASP2 mRNA CTD PMID:16249259 NCBI chr 4:72,116,265...72,134,023 JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
increases cleavage
increases expression
EXP
ISO
2-aminoethoxydiphenylborane inhibits the reaction [cadmium acetate results in increased cleavage of CASP3 protein]; Caspase Inhibitors inhibits the reaction [cadmium acetate results in increased expression of CASP3 protein modified form]; KN 93 inhibits the reaction [cadmium acetate results in increased cleavage of CASP3 protein]; puerarin inhibits the reaction [cadmium acetate results in increased activity of CASP3 protein]; pyrazolanthrone inhibits the reaction [cadmium acetate results in increased cleavage of CASP3 protein]; Thioctic Acid inhibits the reaction [cadmium acetate results in increased expression of CASP3 protein modified form]; U 0126 inhibits the reaction [cadmium acetate results in increased cleavage of CASP3 protein]
Acetylcysteine inhibits the reaction [cadmium acetate results in increased activity of CASP3 protein]; isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone analog inhibits the reaction [cadmium acetate results in increased activity of CASP3 protein]
CTD PMID:15450950 PMID:16169029 PMID:24577723 PMID:25043952 PMID:27717697 More... NCBI chr16:52,395,539...52,413,794 JBrowse link
G Casp6 caspase 6 affects expression EXP cadmium acetate affects the expression of CASP6 mRNA CTD PMID:16249259 NCBI chr 2:221,140,287...221,152,727 JBrowse link
G Casp8 caspase 8 multiple interactions
increases activity
ISO Acetylcysteine inhibits the reaction [cadmium acetate results in increased activity of CASP8 protein]; CASP8 affects the reaction [cadmium acetate results in increased cleavage of BID protein] CTD PMID:15450950 PMID:16169029 NCBI chr 9:67,747,109...67,806,699 JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
increases activity
ISO
EXP
Acetylcysteine inhibits the reaction [cadmium acetate results in increased activity of CASP9 protein]
Thioctic Acid inhibits the reaction [cadmium acetate results in increased expression of CASP9 protein modified form]
CTD PMID:15450950 PMID:16169029 PMID:30605698
G Cat catalase increases expression
increases activity
affects expression
multiple interactions
decreases activity
EXP cadmium acetate results in increased expression of CAT protein
cadmium acetate results in increased activity of CAT protein
cadmium acetate affects the expression of CAT mRNA
[cadmium acetate co-treated with lead acetate] results in increased activity of CAT protein; puerarin inhibits the reaction [cadmium acetate results in increased activity of CAT protein]; Trehalose inhibits the reaction [cadmium acetate results in increased expression of CAT protein]
cadmium acetate results in decreased activity of CAT protein
CTD PMID:16249259 PMID:16897041 PMID:21182167 PMID:23534466 PMID:29140578 More... NCBI chr 3:110,297,340...110,329,526 JBrowse link
G Ccnb1 cyclin B1 affects expression EXP cadmium acetate affects the expression of CCNB1 mRNA CTD PMID:16249259 NCBI chr 2:33,646,252...33,655,225 JBrowse link
G Ccne1 cyclin E1 multiple interactions ISO cadmium acetate results in decreased activity of [CCNE1 protein binds to CDK1 protein] CTD PMID:20839231 NCBI chr 1:99,918,672...99,927,986 JBrowse link
G Cct3 chaperonin containing TCP1 subunit 3 decreases expression ISO cadmium acetate results in decreased expression of CCT3 mRNA CTD PMID:18155341 NCBI chr 2:173,765,701...173,790,353 JBrowse link
G Cd46 CD46 molecule decreases expression ISO cadmium acetate results in decreased expression of CD46 mRNA CTD PMID:18155341 NCBI chr13:109,104,122...109,134,903 JBrowse link
G Cdc42 cell division cycle 42 affects expression EXP cadmium acetate affects the expression of CDC42 mRNA CTD PMID:16249259 NCBI chr 5:154,838,478...154,876,629 JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression
multiple interactions
ISO cadmium acetate results in decreased expression of CDK1 mRNA; cadmium acetate results in decreased expression of CDK1 protein
cadmium acetate promotes the reaction [CDKN1A protein binds to CDK1 protein]; cadmium acetate results in decreased activity of [CCNE1 protein binds to CDK1 protein]
CTD PMID:20839231 NCBI chr20:19,265,252...19,280,456 JBrowse link
G Cdk4 cyclin-dependent kinase 4 affects expression EXP cadmium acetate affects the expression of CDK4 mRNA CTD PMID:16249259 NCBI chr 7:64,771,453...64,774,891 JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression
multiple interactions
increases expression
ISO cadmium acetate results in decreased expression of CDKN1A protein
cadmium acetate promotes the reaction [CDKN1A protein binds to CDK1 protein]
cadmium acetate results in increased expression of CDKN1A mRNA; cadmium acetate results in increased expression of CDKN1A protein
CTD PMID:12965115 PMID:15450950 PMID:20839231 NCBI chr20:7,150,820...7,161,373 JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 affects expression EXP cadmium acetate affects the expression of COX4I1 mRNA CTD PMID:16249259 NCBI chr19:65,630,383...65,636,623 JBrowse link
G Cox5a cytochrome c oxidase subunit 5A affects expression EXP cadmium acetate affects the expression of COX5A mRNA CTD PMID:16249259 NCBI chr 8:66,818,284...66,829,691 JBrowse link
G Cox5b cytochrome c oxidase subunit 5B affects expression EXP cadmium acetate affects the expression of COX5B mRNA CTD PMID:16249259 NCBI chr 9:38,921,980...38,923,806 JBrowse link
G Cox6a1 cytochrome c oxidase subunit 6A1 affects expression EXP cadmium acetate affects the expression of COX6A1 mRNA CTD PMID:16249259 NCBI chr12:41,261,983...41,265,037 JBrowse link
G Cox6a2 cytochrome c oxidase subunit 6A2 affects expression EXP cadmium acetate affects the expression of COX6A2 mRNA CTD PMID:16249259 NCBI chr 1:192,218,970...192,221,188 JBrowse link
G Cox7a2 cytochrome c oxidase subunit 7A2 affects expression EXP cadmium acetate affects the expression of COX7A2 mRNA CTD PMID:16249259 NCBI chr 8:80,716,824...80,720,922 JBrowse link
G Cox8a cytochrome c oxidase subunit 8A affects expression EXP cadmium acetate affects the expression of COX8A mRNA CTD PMID:16249259 NCBI chr 1:213,831,302...213,833,623 JBrowse link
G Creg1 cellular repressor of E1A-stimulated genes 1 decreases expression ISO cadmium acetate results in decreased expression of CREG1 mRNA CTD PMID:18155341 NCBI chr13:80,552,779...80,565,272 JBrowse link
G Cryab crystallin, alpha B affects expression EXP cadmium acetate affects the expression of CRYAB mRNA CTD PMID:16249259 NCBI chr 8:59,989,885...59,995,532 JBrowse link
G Cryz crystallin zeta affects expression EXP cadmium acetate affects the expression of CRYZ mRNA CTD PMID:16249259 NCBI chr 2:246,211,707...246,239,472 JBrowse link
G Ctsk cathepsin K multiple interactions
increases expression
decreases expression
EXP puerarin inhibits the reaction [cadmium acetate results in decreased expression of CTSK protein]; puerarin inhibits the reaction [cadmium acetate results in increased expression of CTSK mRNA] CTD PMID:34897960 NCBI chr 2:185,747,548...185,758,512 JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression
multiple interactions
EXP cadmium acetate results in decreased expression of CYP11A1 mRNA
[cadmium acetate co-treated with lead acetate] results in decreased expression of CYP11A1 mRNA
CTD PMID:21182167 NCBI chr 8:67,318,665...67,330,196 JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 affects expression EXP cadmium acetate affects the expression of CYP1A1 mRNA CTD PMID:16249259 NCBI chr 8:66,991,940...66,998,014 JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 affects expression EXP cadmium acetate affects the expression of CYP2C11 mRNA CTD PMID:16249259 NCBI chr 1:246,175,216...246,211,445 JBrowse link
G Cyp2c12 cytochrome P450, family 2, subfamily c, polypeptide 12 affects expression EXP cadmium acetate affects the expression of CYP2C12 mRNA CTD PMID:16249259 NCBI chr 1:238,699,859...238,757,011 JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 affects expression EXP cadmium acetate affects the expression of CYP3A23-3A1 mRNA CTD PMID:16249259 NCBI chr12:14,369,950...14,398,803 JBrowse link
G Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 affects expression EXP cadmium acetate affects the expression of CYP4F4 mRNA CTD PMID:16249259 NCBI chr 7:11,717,208...11,733,507 JBrowse link
G Cyp51 cytochrome P450, family 51 affects expression EXP cadmium acetate affects the expression of CYP51 mRNA CTD PMID:16249259 NCBI chr 4:30,036,956...30,055,410 JBrowse link
G Dad1 defender against cell death 1 affects expression EXP cadmium acetate affects the expression of DAD1 mRNA CTD PMID:16249259 NCBI chr15:27,677,286...27,697,120 JBrowse link
G Dao D-amino-acid oxidase affects expression EXP cadmium acetate affects the expression of DAO mRNA CTD PMID:16249259 NCBI chr12:42,592,342...42,613,046 JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
EXP cadmium acetate results in increased expression of DDIT3 protein
Chloroquine promotes the reaction [cadmium acetate results in increased expression of DDIT3 protein]; KN 93 inhibits the reaction [cadmium acetate results in increased expression of DDIT3 protein]; salubrinal inhibits the reaction [cadmium acetate results in increased expression of DDIT3 protein]; Sirolimus inhibits the reaction [cadmium acetate results in increased expression of DDIT3 protein]; Thioctic Acid inhibits the reaction [cadmium acetate results in increased expression of DDIT3 protein]; U 0126 promotes the reaction [cadmium acetate results in increased expression of DDIT3 protein]
CTD PMID:29870746 PMID:29883672 PMID:30605698 NCBI chr 7:65,001,695...65,006,517 JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 affects expression EXP cadmium acetate affects the expression of DECR1 mRNA CTD PMID:16249259 NCBI chr 5:29,411,172...29,439,054 JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 affects expression EXP cadmium acetate affects the expression of DNAJA1 mRNA CTD PMID:16249259 NCBI chr 5:55,842,414...55,853,326 JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 increases expression ISO cadmium acetate results in increased expression of DNAJB1 mRNA CTD PMID:18155341 NCBI chr19:41,427,453...41,431,141 JBrowse link
G Dut deoxyuridine triphosphatase affects expression EXP cadmium acetate affects the expression of DUT mRNA CTD PMID:16249259 NCBI chr 3:112,498,864...112,509,994 JBrowse link
G E2f1 E2F transcription factor 1 affects localization
decreases activity
decreases expression
multiple interactions
ISO cadmium acetate affects the localization of E2F1 protein
cadmium acetate results in decreased activity of E2F1 protein
cadmium acetate results in decreased expression of E2F1 mRNA
cadmium acetate promotes the reaction [RB1 protein modified form binds to E2F1 protein]
CTD PMID:18155341 PMID:20839231 NCBI chr 3:163,524,739...163,535,563 JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 increases expression ISO cadmium acetate results in increased expression of EEF1A1 mRNA CTD PMID:12965115 NCBI chr 8:79,341,554...79,344,784 JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases expression
increases phosphorylation
multiple interactions
EXP cadmium acetate results in increased expression of EIF2S1 protein modified form
cadmium acetate results in increased phosphorylation of EIF2S1 protein
salubrinal inhibits the reaction [cadmium acetate results in increased expression of EIF2S1 protein modified form]; Sirolimus inhibits the reaction [cadmium acetate results in increased phosphorylation of EIF2S1 protein]; Thioctic Acid inhibits the reaction [cadmium acetate results in increased expression of EIF2S1 protein modified form]; U 0126 promotes the reaction [cadmium acetate results in increased phosphorylation of EIF2S1 protein]
CTD PMID:29870746 PMID:30605698 NCBI chr 6:103,405,880...103,430,549 JBrowse link
G Endog endonuclease G affects localization
multiple interactions
EXP cadmium acetate affects the localization of ENDOG protein
pyrazolanthrone inhibits the reaction [cadmium acetate affects the localization of ENDOG protein]; U 0126 inhibits the reaction [cadmium acetate affects the localization of ENDOG protein]
CTD PMID:24577723 NCBI chr 3:13,449,113...13,451,715 JBrowse link
G Eno1 enolase 1 increases expression
decreases expression
ISO cadmium acetate results in increased expression of ENO1 mRNA
cadmium acetate results in decreased expression of ENO1 mRNA
CTD PMID:12965115 PMID:18155341 NCBI chr 5:160,719,951...160,731,337 JBrowse link
G Ephx1 epoxide hydrolase 1 affects expression EXP cadmium acetate affects the expression of EPHX1 mRNA CTD PMID:16249259 NCBI chr13:95,246,079...95,275,852 JBrowse link
G Ephx2 epoxide hydrolase 2 affects expression EXP cadmium acetate affects the expression of EPHX2 mRNA CTD PMID:16249259 NCBI chr15:40,289,901...40,327,632 JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of FAS protein] CTD PMID:16169029 NCBI chr 1:241,212,155...241,245,774 JBrowse link
G Fbln1 fibulin 1 decreases expression ISO cadmium acetate results in decreased expression of FBLN1 mRNA CTD PMID:18155341 NCBI chr 7:116,310,582...116,390,075 JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression ISO cadmium acetate results in increased expression of FOSB mRNA CTD PMID:18155341 NCBI chr 1:88,082,324...88,089,506 JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit affects expression EXP cadmium acetate affects the expression of FOSL2 mRNA CTD PMID:16249259 NCBI chr 6:30,017,952...30,039,269 JBrowse link
G Ftl1 ferritin light chain 1 increases expression ISO cadmium acetate results in increased expression of FTL mRNA CTD PMID:12965115 NCBI chr 1:105,072,858...105,074,705 JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha affects expression EXP cadmium acetate affects the expression of GADD45A mRNA CTD PMID:16249259 NCBI chr 4:97,484,497...97,486,799 JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
multiple interactions
EXP cadmium acetate results in increased expression of GCLC protein
Trehalose inhibits the reaction [cadmium acetate results in increased expression of GCLC protein]
CTD PMID:29140578 NCBI chr 8:87,510,251...87,548,896 JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions
increases expression
EXP Trehalose inhibits the reaction [cadmium acetate results in increased expression of GCLM protein] CTD PMID:29140578 NCBI chr 2:213,032,135...213,052,192 JBrowse link
G Gpi glucose-6-phosphate isomerase multiple interactions EXP [cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of GPI mRNA; puerarin inhibits the reaction [[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of GPI mRNA] CTD PMID:33404196 NCBI chr 1:86,828,211...86,856,077 JBrowse link
G Gpt glutamic--pyruvic transaminase increases expression ISO cadmium acetate results in increased expression of GPT protein CTD PMID:37128655 NCBI chr 7:110,295,599...110,300,134 JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
increases expression
EXP Trehalose inhibits the reaction [cadmium acetate results in increased expression of GPX1 protein] CTD PMID:29140578 NCBI chr 8:117,905,462...117,906,588 JBrowse link
G Gsdmd gasdermin D multiple interactions
increases expression
EXP Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of GSDMD protein] CTD PMID:36347317 NCBI chr 7:109,423,209...109,427,771 JBrowse link
G Gsr glutathione-disulfide reductase increases expression
decreases activity
affects expression
multiple interactions
EXP cadmium acetate results in increased expression of GSR protein
cadmium acetate results in decreased activity of GSR protein
cadmium acetate affects the expression of GSR mRNA
Trehalose inhibits the reaction [cadmium acetate results in increased expression of GSR protein]
CTD PMID:16249259 PMID:21182167 PMID:29140578 NCBI chr16:65,185,574...65,228,742 JBrowse link
G Gsta3 glutathione S-transferase alpha 3 affects expression EXP cadmium acetate affects the expression of GSTA3 mRNA CTD PMID:16249259 NCBI chr 9:23,658,574...23,684,240 JBrowse link
G Gstm1 glutathione S-transferase mu 1 affects expression EXP cadmium acetate affects the expression of GSTM1 mRNA CTD PMID:16249259 NCBI chr 2:198,338,005...198,346,007 JBrowse link
G Hk1 hexokinase 1 multiple interactions EXP [cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of HK1 mRNA; puerarin inhibits the reaction [[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of HK1 mRNA] CTD PMID:33404196 NCBI chr20:30,773,222...30,874,814 JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
EXP
ISO
cadmium acetate results in increased expression of HMOX1 protein
cadmium acetate results in increased expression of HMOX1 mRNA; cadmium acetate results in increased expression of HMOX1 protein
Trehalose inhibits the reaction [cadmium acetate results in increased expression of HMOX1 protein]
Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of HMOX1 protein]; cadmium acetate results in increased expression of and affects the localization of HMOX1 protein
CTD PMID:12965115 PMID:18155341 PMID:21787718 PMID:27427241 PMID:29140578 NCBI chr19:13,452,365...13,479,823 JBrowse link
G Hmox2 heme oxygenase 2 affects expression EXP cadmium acetate affects the expression of HMOX2 mRNA CTD PMID:16249259 NCBI chr10:10,797,076...10,831,178 JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 affects expression EXP cadmium acetate affects the expression of HSP90AA1 mRNA CTD PMID:16249259 NCBI chr 6:135,523,604...135,529,687 JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A affects expression EXP cadmium acetate affects the expression of HSPA1A mRNA CTD PMID:16249259 NCBI chr20:3,875,411...3,877,866 JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions
EXP cadmium acetate results in increased expression of HSPA5 protein
Chloroquine promotes the reaction [cadmium acetate results in increased expression of HSPA5 protein]; KN 93 inhibits the reaction [cadmium acetate results in increased expression of HSPA5 protein]; Sirolimus inhibits the reaction [cadmium acetate results in increased expression of HSPA5 protein]; Thioctic Acid inhibits the reaction [cadmium acetate results in increased expression of HSPA5 protein]; U 0126 promotes the reaction [cadmium acetate results in increased expression of HSPA5 protein]
CTD PMID:29870746 PMID:29883672 PMID:30605698 NCBI chr 3:38,453,016...38,457,475 JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 affects expression EXP cadmium acetate affects the expression of HSPA8 mRNA CTD PMID:16249259 NCBI chr 8:50,080,514...50,084,376 JBrowse link
G Hspb1 heat shock protein family B (small) member 1 affects expression EXP cadmium acetate affects the expression of HSPB1 mRNA CTD PMID:16249259 NCBI chr12:26,430,640...26,432,301 JBrowse link
G Hspb2 heat shock protein family B (small) member 2 affects expression EXP cadmium acetate affects the expression of HSPB2 mRNA CTD PMID:16249259 NCBI chr 8:59,989,640...59,991,215 JBrowse link
G Ifng interferon gamma decreases secretion ISO cadmium acetate results in decreased secretion of IFNG protein CTD PMID:16510232 NCBI chr 7:55,789,180...55,793,216 JBrowse link
G Ifngr2 interferon gamma receptor 2 decreases expression ISO cadmium acetate results in decreased expression of IFNGR2 mRNA CTD PMID:18155341 NCBI chr11:44,265,703...44,283,975 JBrowse link
G Il10 interleukin 10 decreases secretion
increases expression
ISO cadmium acetate results in decreased secretion of IL10 protein
cadmium acetate results in increased expression of IL10 mRNA
CTD PMID:16510232 PMID:27427241 NCBI chr13:45,024,921...45,029,586 JBrowse link
G Il1b interleukin 1 beta increases secretion
multiple interactions
increases cleavage
decreases secretion
EXP
ISO
cadmium acetate results in increased secretion of IL1B protein
Acetylcysteine inhibits the reaction [cadmium acetate results in increased cleavage of IL1B protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased secretion of IL1B protein]
cadmium acetate results in decreased secretion of IL1B protein
CTD PMID:16510232 PMID:36347317 NCBI chr 3:137,030,200...137,036,581 JBrowse link
G Il1r2 interleukin 1 receptor type 2 affects expression EXP cadmium acetate affects the expression of IL1R2 mRNA CTD PMID:16249259 NCBI chr 9:42,384,280...42,424,726 JBrowse link
G Il6 interleukin 6 increases secretion
multiple interactions
increases expression
ISO cadmium acetate results in increased secretion of IL6 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [cadmium acetate results in increased secretion of IL6 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [cadmium acetate results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased secretion of IL6 protein]; pyrazolanthrone promotes the reaction [cadmium acetate results in increased secretion of IL6 protein]; RELA protein affects the reaction [cadmium acetate results in increased secretion of IL6 protein]; Thiourea inhibits the reaction [cadmium acetate results in increased secretion of IL6 protein]
cadmium acetate results in increased expression of IL6 mRNA
CTD PMID:27427241 NCBI chr 4:5,889,999...5,894,575 JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit affects expression EXP cadmium acetate affects the expression of JUN mRNA CTD PMID:16249259 NCBI chr 5:115,009,900...115,012,993 JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit affects expression EXP cadmium acetate affects the expression of JUNB mRNA CTD PMID:16249259 NCBI chr19:23,176,265...23,178,049 JBrowse link
G Kalrn kalirin, RhoGEF kinase decreases expression ISO cadmium acetate results in decreased expression of KALRN mRNA CTD PMID:18155341 NCBI chr11:79,703,345...80,309,210 JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 decreases expression
multiple interactions
EXP cadmium acetate results in decreased expression of KEAP1 protein
Trehalose inhibits the reaction [cadmium acetate results in decreased expression of KEAP1 protein]
CTD PMID:29140578 NCBI chr 8:19,768,375...19,777,862 JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 multiple interactions EXP 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [cadmium acetate affects the localization of [LAMP1 protein co-treated with MAP1LC3B protein]]; 2-aminoethoxydiphenyl borate inhibits the reaction [cadmium acetate affects the localization of [LAMP1 protein co-treated with MAP1LC3B protein]]; Acetylcysteine inhibits the reaction [cadmium acetate affects the localization of [LAMP1 protein co-treated with MAP1LC3B protein]]; cadmium acetate affects the localization of [LAMP1 protein co-treated with MAP1LC3B protein]; Thapsigargin promotes the reaction [cadmium acetate affects the localization of [LAMP1 protein co-treated with MAP1LC3B protein]] CTD PMID:28347754 NCBI chr16:83,058,131...83,082,843 JBrowse link
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 decreases expression
multiple interactions
EXP cadmium acetate results in decreased expression of LAMTOR1 protein
puerarin promotes the reaction [cadmium acetate results in decreased expression of LAMTOR1 protein]
CTD PMID:34897960 NCBI chr 1:165,684,001...165,689,698 JBrowse link
G Ldha lactate dehydrogenase A multiple interactions EXP [cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of LDHA protein; puerarin inhibits the reaction [[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of LDHA protein] CTD PMID:33404196 NCBI chr 1:97,371,823...97,381,247 JBrowse link
G Lta lymphotoxin alpha affects expression EXP cadmium acetate affects the expression of LTA mRNA CTD PMID:16249259 NCBI chr20:3,622,291...3,625,852 JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 decreases expression ISO cadmium acetate results in decreased expression of MAD2L1 mRNA CTD PMID:18155341 NCBI chr 4:97,236,419...97,247,603 JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions
decreases expression
EXP 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [cadmium acetate affects the localization of [LAMP1 protein co-treated with MAP1LC3B protein]]; 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [cadmium acetate affects the localization of [RAB7A protein co-treated with MAP1LC3B protein]]; 2-aminoethoxydiphenyl borate inhibits the reaction [cadmium acetate affects the localization of [LAMP1 protein co-treated with MAP1LC3B protein]]; 2-aminoethoxydiphenyl borate inhibits the reaction [cadmium acetate affects the localization of [RAB7A protein co-treated with MAP1LC3B protein]]; Acetylcysteine inhibits the reaction [cadmium acetate affects the localization of [LAMP1 protein co-treated with MAP1LC3B protein]]; Acetylcysteine inhibits the reaction [cadmium acetate affects the localization of [RAB7A protein co-treated with MAP1LC3B protein]]; cadmium acetate affects the localization of [LAMP1 protein co-treated with MAP1LC3B protein]; cadmium acetate affects the localization of [RAB7A protein co-treated with MAP1LC3B protein]; puerarin inhibits the reaction [cadmium acetate results in decreased expression of MAP1LC3B protein modified form]; Thapsigargin promotes the reaction [cadmium acetate affects the localization of [LAMP1 protein co-treated with MAP1LC3B protein]]; Thapsigargin promotes the reaction [cadmium acetate affects the localization of [RAB7A protein co-treated with MAP1LC3B protein]] CTD PMID:28347754 PMID:34897960 NCBI chr19:66,571,631...66,582,270 JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 affects expression EXP cadmium acetate affects the expression of MAP2K1 mRNA CTD PMID:16249259 NCBI chr 8:73,578,747...73,650,184 JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 affects expression EXP cadmium acetate affects the expression of MAP2K2 mRNA CTD PMID:16249259 NCBI chr 7:9,241,449...9,264,216 JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 increases expression
affects expression
ISO
EXP
cadmium acetate results in increased expression of MAP2K5 mRNA
cadmium acetate affects the expression of MAP2K5 mRNA
CTD PMID:12965115 PMID:16249259 NCBI chr 8:72,520,616...72,748,395 JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 affects expression EXP cadmium acetate affects the expression of MAP3K1 mRNA CTD PMID:16249259 NCBI chr 2:45,081,889...45,150,555 JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
affects expression
EXP KN 93 inhibits the reaction [cadmium acetate results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [cadmium acetate results in increased phosphorylation of MAPK1 protein]
cadmium acetate affects the expression of MAPK1 mRNA
CTD PMID:15925026 PMID:16249259 PMID:24577723 PMID:25043952 PMID:29870746 More... NCBI chr11:97,462,025...97,529,193 JBrowse link
G Mapk14 mitogen activated protein kinase 14 affects expression
increases phosphorylation
multiple interactions
EXP cadmium acetate affects the expression of MAPK14 mRNA
cadmium acetate results in increased phosphorylation of MAPK14 protein
bisindolylmaleimide I inhibits the reaction [cadmium acetate results in increased phosphorylation of MAPK14 protein]
CTD PMID:15925026 PMID:16249259 PMID:29870746 NCBI chr20:6,751,288...6,812,294 JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
EXP KN 93 inhibits the reaction [cadmium acetate results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [cadmium acetate results in increased phosphorylation of MAPK3 protein] CTD PMID:15925026 PMID:24577723 PMID:25043952 PMID:29870746 PMID:29883672 NCBI chr 1:190,797,189...190,803,411 JBrowse link
G Mapk6 mitogen-activated protein kinase 6 affects expression EXP cadmium acetate affects the expression of MAPK6 mRNA CTD PMID:16249259 NCBI chr 8:85,027,141...85,050,236 JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation EXP cadmium acetate results in increased phosphorylation of MAPK8 protein CTD PMID:15925026 NCBI chr16:8,645,171...8,728,225 JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO cadmium acetate results in increased expression of MDM2 protein CTD PMID:15450950 NCBI chr 7:55,176,558...55,201,757 JBrowse link
G Mif macrophage migration inhibitory factor increases expression ISO cadmium acetate results in increased expression of MIF mRNA CTD PMID:12965115 NCBI chr20:12,790,919...12,791,784 JBrowse link
G Mta1 metastasis associated 1 increases expression ISO cadmium acetate results in increased expression of MTA1 mRNA CTD PMID:18155341 NCBI chr 6:137,999,845...138,038,696 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor affects expression EXP cadmium acetate affects the expression of MYC mRNA CTD PMID:16249259 NCBI chr 7:95,483,105...95,488,031 JBrowse link
G Naa80 N(alpha)-acetyltransferase 80, NatH catalytic subunit increases expression ISO cadmium acetate results in increased expression of NAA80 mRNA CTD PMID:12965115 NCBI chr 8:108,254,314...108,257,564 JBrowse link
G Ncl nucleolin decreases expression ISO cadmium acetate results in decreased expression of NCL mRNA CTD PMID:18155341 NCBI chr 9:94,447,559...94,456,083 JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of NFE2L2 protein]; cadmium acetate results in increased expression of and affects the localization of NFE2L2 protein CTD PMID:21787718 NCBI chr 3:81,001,529...81,031,165 JBrowse link
G Ngf nerve growth factor multiple interactions EXP cadmium acetate inhibits the reaction [NGF protein results in increased uptake of Calcium] CTD PMID:1374475 NCBI chr 2:192,589,580...192,642,971 JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions
increases expression
EXP Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of NLRP3 protein] CTD PMID:36347317 NCBI chr10:44,826,299...44,853,373 JBrowse link
G Nmt1 N-myristoyltransferase 1 decreases expression ISO cadmium acetate results in decreased expression of NMT1 mRNA CTD PMID:18155341 NCBI chr10:87,988,826...88,025,405 JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions
EXP cadmium acetate results in increased expression of NQO1 protein
Trehalose inhibits the reaction [cadmium acetate results in increased expression of NQO1 protein]
CTD PMID:29140578 NCBI chr19:52,205,374...52,220,267 JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions
increases expression
ISO
EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [cadmium acetate results in increased expression of NR4A1 protein]; cadmium acetate results in increased expression of and results in increased activity of NR4A1 protein; Cyclosporine inhibits the reaction [cadmium acetate results in increased expression of NR4A1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [cadmium acetate results in increased expression of NR4A1 protein]
cadmium acetate results in increased expression of NR4A1 mRNA; cadmium acetate results in increased expression of NR4A1 protein
CTD PMID:15016657 NCBI chr 7:132,368,399...132,389,300 JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 increases expression ISO
EXP
cadmium acetate results in increased expression of NR4A2 mRNA CTD PMID:15016657 NCBI chr 3:41,689,847...41,707,036 JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 increases expression EXP
ISO
cadmium acetate results in increased expression of NR4A3 mRNA CTD PMID:12965115 PMID:15016657 NCBI chr 5:67,157,141...67,198,287 JBrowse link
G Pabpc4 poly(A) binding protein, cytoplasmic 4 decreases expression ISO cadmium acetate results in decreased expression of PABPC4 mRNA CTD PMID:18155341 NCBI chr 5:135,563,142...135,578,985 JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
affects expression
increases cleavage
EXP
ISO
puerarin inhibits the reaction [cadmium acetate results in increased cleavage of PARP1 protein]; pyrazolanthrone inhibits the reaction [cadmium acetate results in increased cleavage of PARP1 protein]; U 0126 inhibits the reaction [cadmium acetate results in increased cleavage of PARP1 protein]
cadmium acetate affects the expression of PARP1 mRNA
CTD PMID:15450950 PMID:16249259 PMID:24577723 PMID:25043952 PMID:27717697 NCBI chr13:94,839,484...94,871,295 JBrowse link
G Pfkp phosphofructokinase, platelet multiple interactions EXP [cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of PFKP mRNA; puerarin inhibits the reaction [[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of PFKP mRNA] CTD PMID:33404196 NCBI chr17:68,639,749...68,704,055 JBrowse link
G Pgam1 phosphoglycerate mutase 1 multiple interactions EXP [cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of PGAM1 mRNA; puerarin inhibits the reaction [[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of PGAM1 mRNA] CTD PMID:33404196 NCBI chr 1:250,673,152...250,680,762 JBrowse link
G Plp2 proteolipid protein 2 decreases expression ISO cadmium acetate results in decreased expression of PLP2 mRNA CTD PMID:18155341 NCBI chr  X:14,834,249...14,837,648 JBrowse link
G Pnkd PNKD metallo-beta-lactamase domain containing increases expression ISO cadmium acetate results in increased expression of PNKD mRNA CTD PMID:12965115 NCBI chr 9:75,868,620...75,937,126 JBrowse link
G Pola1 DNA polymerase alpha 1, catalytic subunit decreases expression ISO cadmium acetate results in decreased expression of POLA1 mRNA CTD PMID:20839231 NCBI chr  X:62,028,475...62,342,455 JBrowse link
G Polb DNA polymerase beta affects expression EXP cadmium acetate affects the expression of POLB mRNA CTD PMID:16249259 NCBI chr16:69,379,438...69,402,710 JBrowse link
G Por cytochrome p450 oxidoreductase affects expression EXP cadmium acetate affects the expression of POR mRNA CTD PMID:16249259 NCBI chr12:26,587,674...26,655,612 JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions EXP [cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of PPARGC1A protein; puerarin inhibits the reaction [[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of PPARGC1A protein] CTD PMID:33404196 NCBI chr14:63,073,505...63,729,215 JBrowse link
G Prdx2 peroxiredoxin 2 affects expression EXP cadmium acetate affects the expression of PRDX2 mRNA CTD PMID:16249259 NCBI chr19:23,180,927...23,186,217 JBrowse link
G Prss23 serine protease 23 decreases expression ISO cadmium acetate results in decreased expression of PRSS23 mRNA CTD PMID:18155341 NCBI chr 1:143,402,725...143,422,182 JBrowse link
G Ptbp1 polypyrimidine tract binding protein 1 increases expression ISO cadmium acetate results in increased expression of PTBP1 mRNA CTD PMID:12965115 NCBI chr 7:9,842,574...9,852,332 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO cadmium acetate results in increased expression of PTGS2 mRNA CTD PMID:12965115 NCBI chr13:64,714,063...64,722,320 JBrowse link
G Rab7a RAB7A, member RAS oncogene family decreases expression
multiple interactions
EXP cadmium acetate results in decreased expression of RAB7A protein
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [cadmium acetate affects the localization of [RAB7A protein co-treated with MAP1LC3B protein]]; 2-aminoethoxydiphenyl borate inhibits the reaction [cadmium acetate affects the localization of [RAB7A protein co-treated with MAP1LC3B protein]]; Acetylcysteine inhibits the reaction [cadmium acetate affects the localization of [RAB7A protein co-treated with MAP1LC3B protein]]; cadmium acetate affects the localization of [RAB7A protein co-treated with MAP1LC3B protein]; Thapsigargin promotes the reaction [cadmium acetate affects the localization of [RAB7A protein co-treated with MAP1LC3B protein]]
CTD PMID:28347754 PMID:34897960 NCBI chr 4:120,461,966...120,510,756 JBrowse link
G Rad23b RAD23 homolog B, nucleotide excision repair protein decreases expression ISO cadmium acetate results in decreased expression of RAD23B mRNA CTD PMID:18155341 NCBI chr 5:70,090,232...70,128,340 JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions
decreases phosphorylation
decreases expression
ISO cadmium acetate promotes the reaction [RB1 protein modified form binds to E2F1 protein]
cadmium acetate results in decreased phosphorylation of RB1 protein
cadmium acetate results in decreased expression of RB1 mRNA
CTD PMID:20839231 NCBI chr15:54,780,858...54,911,989 JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO RELA protein affects the reaction [cadmium acetate results in increased secretion of IL6 protein] CTD PMID:27427241 NCBI chr 1:212,354,336...212,364,815 JBrowse link
G Rgs2 regulator of G-protein signaling 2 increases expression ISO cadmium acetate results in increased expression of RGS2 mRNA CTD PMID:18155341 NCBI chr13:58,350,063...58,352,666 JBrowse link
G Rps6ka1 ribosomal protein S6 kinase A1 affects expression EXP cadmium acetate affects the expression of RPS6KA1 mRNA CTD PMID:16249259 NCBI chr 5:151,362,819...151,402,064 JBrowse link
G RT1-CE5 RT1 class I, locus CE5 decreases expression ISO cadmium acetate results in decreased expression of HLA-F mRNA CTD PMID:18155341 NCBI chr20:3,403,418...3,479,476 JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions
decreases expression
EXP puerarin inhibits the reaction [cadmium acetate results in decreased expression of RUNX2 protein] CTD PMID:34897960 NCBI chr 9:23,661,278...23,990,248 JBrowse link
G S100a6 S100 calcium binding protein A6 increases expression ISO cadmium acetate results in increased expression of S100A6 mRNA CTD PMID:12965115 NCBI chr 2:178,398,189...178,399,763 JBrowse link
G Sirt1 sirtuin 1 multiple interactions EXP [cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of SIRT1 protein; puerarin inhibits the reaction [[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of SIRT1 protein] CTD PMID:33404196 NCBI chr20:25,305,953...25,328,000 JBrowse link
G Slc25a4 solute carrier family 25 member 4 increases expression
multiple interactions
EXP cadmium acetate results in increased expression of SLC25A4 mRNA; cadmium acetate results in increased expression of SLC25A4 protein
puerarin inhibits the reaction [cadmium acetate results in increased expression of SLC25A4 mRNA]; puerarin inhibits the reaction [cadmium acetate results in increased expression of SLC25A4 protein]
CTD PMID:27717697 NCBI chr16:46,072,935...46,076,730 JBrowse link
G Slc25a5 solute carrier family 25 member 5 multiple interactions
decreases expression
EXP puerarin inhibits the reaction [cadmium acetate results in decreased expression of SLC25A5 mRNA]; puerarin inhibits the reaction [cadmium acetate results in decreased expression of SLC25A5 protein]
cadmium acetate results in decreased expression of SLC25A5 mRNA; cadmium acetate results in decreased expression of SLC25A5 protein
CTD PMID:27717697 NCBI chr  X:120,897,616...120,900,683 JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions EXP [cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of SLC2A1 protein; puerarin inhibits the reaction [[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of SLC2A1 protein] CTD PMID:33404196 NCBI chr 5:138,002,522...138,030,742 JBrowse link
G Slc31a1 solute carrier family 31 member 1 decreases expression ISO cadmium acetate results in decreased expression of SLC31A1 mRNA CTD PMID:24132751 NCBI chr 5:75,814,744...75,844,241 JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
increases expression
decreases activity
EXP Trehalose inhibits the reaction [cadmium acetate results in increased expression of SOD1 protein]
cadmium acetate results in decreased activity of SOD1 protein
CTD PMID:21182167 PMID:29140578 NCBI chr11:42,942,742...42,948,399 JBrowse link
G Sod2 superoxide dismutase 2 increases expression
multiple interactions
decreases activity
EXP cadmium acetate results in increased expression of SOD2 protein
Trehalose inhibits the reaction [cadmium acetate results in increased expression of SOD2 protein]
cadmium acetate results in decreased activity of SOD2 protein
CTD PMID:21182167 PMID:29140578 NCBI chr 1:50,043,323...50,050,168 JBrowse link
G Sp1 Sp1 transcription factor decreases expression ISO cadmium acetate results in decreased expression of SP1 mRNA CTD PMID:24132751 NCBI chr 7:135,419,864...135,450,513 JBrowse link
G Sqstm1 sequestosome 1 multiple interactions
decreases expression
increases expression
EXP [Sirolimus co-treated with cadmium acetate] results in decreased expression of SQSTM1 mRNA; Chloroquine inhibits the reaction [cadmium acetate results in decreased expression of SQSTM1 protein]; puerarin promotes the reaction [cadmium acetate results in increased expression of SQSTM1 protein]; U 0126 inhibits the reaction [cadmium acetate results in decreased expression of SQSTM1 protein] CTD PMID:28347754 PMID:29870746 PMID:34897960 NCBI chr10:35,026,598...35,037,750 JBrowse link
G Ssrp1 structure specific recognition protein 1 affects expression EXP cadmium acetate affects the expression of SSRP1 mRNA CTD PMID:16249259 NCBI chr 3:70,124,371...70,134,481 JBrowse link
G Stac SH3 and cysteine rich domain increases expression ISO cadmium acetate results in increased expression of STAC mRNA CTD PMID:18155341 NCBI chr 8:111,530,800...111,653,228 JBrowse link
G Star steroidogenic acute regulatory protein decreases expression EXP cadmium acetate results in decreased expression of STAR mRNA CTD PMID:21182167 NCBI chr16:72,969,824...72,974,447 JBrowse link
G Stat5b signal transducer and activator of transcription 5B affects expression EXP cadmium acetate affects the expression of STAT5B mRNA CTD PMID:16249259 NCBI chr10:85,704,841...85,775,856 JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 affects expression EXP cadmium acetate affects the expression of SULT1A1 mRNA CTD PMID:16249259 NCBI chr 1:190,702,592...190,706,112 JBrowse link
G Sult1c3 sulfotransferase family 1C member 3 affects expression EXP cadmium acetate affects the expression of SULT1C3 mRNA CTD PMID:16249259 NCBI chr 9:7,221,580...7,266,991 JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 affects expression EXP cadmium acetate affects the expression of SULT1E1 mRNA CTD PMID:16249259 NCBI chr14:20,422,324...20,439,562 JBrowse link
G Taf10 TATA-box binding protein associated factor 10 increases expression ISO cadmium acetate results in increased expression of TAF10 mRNA CTD PMID:12965115 NCBI chr 1:160,095,108...160,096,401 JBrowse link
G Taok1 TAO kinase 1 affects expression EXP cadmium acetate affects the expression of TAOK1 mRNA CTD PMID:16249259 NCBI chr10:62,871,198...62,989,049 JBrowse link
G Tfeb transcription factor EB multiple interactions EXP cadmium acetate affects the localization of and results in decreased expression of TFEB protein CTD PMID:36347317 NCBI chr 9:20,696,440...20,752,265 JBrowse link
G Tk1 thymidine kinase 1 decreases expression ISO cadmium acetate results in decreased expression of TK1 mRNA CTD PMID:20839231 NCBI chr10:103,533,449...103,544,818 JBrowse link
G Tmsb4x thymosin beta 4, X-linked increases expression ISO cadmium acetate results in increased expression of TMSB4X mRNA CTD PMID:12965115 NCBI chr  X:30,761,611...30,763,612 JBrowse link
G Tnf tumor necrosis factor decreases secretion ISO cadmium acetate results in decreased secretion of TNF protein CTD PMID:16510232 NCBI chr20:3,626,685...3,629,303 JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B increases expression
multiple interactions
EXP cadmium acetate results in increased expression of TNFRSF11B mRNA
puerarin promotes the reaction [cadmium acetate results in increased expression of TNFRSF11B mRNA]
CTD PMID:34897960 NCBI chr 7:87,456,318...87,484,324 JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A affects expression EXP cadmium acetate affects the expression of TNFRSF1A mRNA CTD PMID:16249259 NCBI chr 4:159,837,119...159,849,817 JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions EXP [cadmium acetate co-treated with puerarin] results in increased expression of TNFSF11 mRNA CTD PMID:34897960 NCBI chr15:60,083,008...60,114,479 JBrowse link
G Tp53 tumor protein p53 increases phosphorylation
multiple interactions
decreases expression
ISO cadmium acetate results in increased phosphorylation of TP53 protein
cadmium acetate results in increased degradation of and affects the localization of TP53 protein
cadmium acetate results in decreased expression of TP53 mRNA
CTD PMID:15450950 PMID:18155341 PMID:20839231 NCBI chr10:54,798,871...54,810,300 JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression ISO cadmium acetate results in increased expression of TPI1 mRNA CTD PMID:12965115 NCBI chr 4:159,301,558...159,305,088 JBrowse link
G Tubb5 tubulin, beta 5 class I decreases expression ISO cadmium acetate results in decreased expression of TUBB mRNA CTD PMID:18155341 NCBI chr20:2,917,577...2,921,726 JBrowse link
G Ubl5 ubiquitin-like 5 increases expression ISO cadmium acetate results in increased expression of UBL5 mRNA CTD PMID:12965115 NCBI chr 8:19,181,504...19,185,224 JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions EXP [cadmium acetate results in increased abundance of Cadmium] which results in increased expression of UCP2 protein; puerarin inhibits the reaction [[cadmium acetate results in increased abundance of Cadmium] which results in increased expression of UCP2 protein] CTD PMID:33404196 NCBI chr 1:164,251,373...164,257,742 JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 affects expression EXP cadmium acetate affects the expression of UGT1A6 mRNA CTD PMID:16249259 NCBI chr 9:96,195,018...96,256,264 JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 affects expression EXP cadmium acetate affects the expression of UGT2B17 mRNA CTD PMID:16249259 NCBI chr14:21,378,882...21,390,631 JBrowse link
G Ugt2b15 UDP glucuronosyltransferase family 2 member B15 affects expression EXP cadmium acetate affects the expression of UGT2B15 mRNA CTD PMID:16249259 NCBI chr14:20,768,015...20,783,599 JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 affects expression EXP cadmium acetate affects the expression of UGT2B7 mRNA CTD PMID:16249259 NCBI chr14:21,251,535...21,274,451 JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO cadmium acetate results in increased expression of VEGFA mRNA CTD PMID:12965115 NCBI chr 9:22,452,854...22,468,194 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19898
    role 19869
      biological role 19867
        aetiopathogenetic role 19243
          carcinogenic agent 18548
            cadmium acetate 191
Path 2
Term Annotations click to browse term
  CHEBI ontology 19898
    subatomic particle 19896
      composite particle 19896
        hadron 19896
          baryon 19896
            nucleon 19896
              atomic nucleus 19896
                atom 19896
                  main group element atom 19835
                    p-block element atom 19835
                      carbon group element atom 19774
                        carbon atom 19770
                          organic molecular entity 19770
                            cadmium acetate 191
paths to the root