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G |
Ache |
acetylcholinesterase |
multiple interactions |
EXP |
diphenyldiselenide inhibits the reaction [Chlorpyrifos results in decreased activity of ACHE protein] |
CTD |
PMID:30267645 |
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NCBI chr12:25,042,882...25,050,608
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G |
Afp |
alpha-fetoprotein |
multiple interactions |
EXP |
diphenyldiselenide inhibits the reaction [2-nitropropane results in increased expression of AFP protein] |
CTD |
PMID:15804453 |
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NCBI chr14:17,573,412...17,591,476
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G |
Alad |
aminolevulinate dehydratase |
decreases activity multiple interactions |
EXP ISO |
diphenyldiselenide results in decreased activity of ALAD protein [diphenyldiselenide co-treated with Succimer] inhibits the reaction [Cadmium Chloride results in decreased activity of ALAD protein]; [Mercuric Chloride co-treated with diphenyldiselenide] results in decreased activity of ALAD protein; Cadmium Chloride inhibits the reaction [diphenyldiselenide results in decreased activity of ALAD protein]; diphenyldiselenide inhibits the reaction [Cadmium Chloride results in decreased activity of ALAD protein]; diphenyldiselenide inhibits the reaction [Mercuric Chloride results in decreased activity of ALAD protein]; Dithiothreitol inhibits the reaction [Cadmium Chloride inhibits the reaction [diphenyldiselenide results in decreased activity of ALAD protein]] [diphenyldiselenide co-treated with diphenyldiselenide] results in decreased activity of ALAD protein; [Fluphenazine co-treated with diphenyldiselenide] results in decreased activity of ALAD protein; diphenyldiselenide inhibits the reaction [Glycerol results in decreased activity of ALAD protein]; Glutathione inhibits the reaction [diphenyldiselenide results in decreased activity of ALAD protein] |
CTD |
PMID:15331134 PMID:16000234 PMID:17822862 PMID:17975852 PMID:18804525 PMID:18989868 PMID:19484701 PMID:19486337 PMID:20472051 PMID:20583318 PMID:21259295 PMID:21620807 PMID:24954677 More...
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NCBI chr 5:75,961,993...75,972,334
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G |
Alb |
albumin |
multiple interactions |
EXP |
diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of ALB protein] |
CTD |
PMID:33639173 |
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NCBI chr14:17,891,564...17,907,043
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|
G |
B2m |
beta-2 microglobulin |
multiple interactions |
EXP |
diphenyldiselenide inhibits the reaction [Streptozocin results in increased activity of B2M protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of B2M protein] |
CTD |
PMID:33639173 |
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NCBI chr 3:129,549,236...129,555,354
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G |
Bdnf |
brain-derived neurotrophic factor |
multiple interactions |
ISO |
diphenyldiselenide inhibits the reaction [methylmercuric chloride results in decreased expression of BDNF protein] |
CTD |
PMID:23954720 |
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NCBI chr 3:116,619,633...116,670,212
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G |
Cat |
catalase |
multiple interactions increases activity decreases activity |
ISO EXP |
[Mercuric Chloride co-treated with diphenyldiselenide] results in decreased activity of CAT protein; diphenyldiselenide inhibits the reaction [Cadmium Chloride results in decreased activity of CAT protein] diphenyldiselenide results in increased activity of CAT protein diphenyldiselenide results in decreased activity of CAT protein [diphenyldiselenide co-treated with diphenyldiselenide] promotes the reaction [Carbon Tetrachloride results in decreased activity of CAT protein]; diphenyldiselenide inhibits the reaction [2-nitropropane results in decreased activity of CAT protein]; diphenyldiselenide inhibits the reaction [Chlorpyrifos results in decreased activity of CAT protein]; diphenyldiselenide inhibits the reaction [Fluphenazine results in increased activity of CAT protein]; diphenyldiselenide inhibits the reaction [Glycerol results in decreased activity of CAT protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of CAT mRNA]; Glutathione inhibits the reaction [diphenyldiselenide results in decreased activity of CAT protein] |
CTD |
PMID:16445897 PMID:17822862 PMID:18818063 PMID:18989868 PMID:19484701 PMID:19486337 PMID:20583318 PMID:21259295 PMID:21620807 PMID:30267645 PMID:33639173 More...
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NCBI chr 3:110,297,340...110,329,526
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions |
EXP |
diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA] |
CTD |
PMID:33639173 |
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NCBI chr10:67,503,077...67,504,875
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G |
Cs |
citrate synthase |
multiple interactions |
EXP |
diphenyldiselenide inhibits the reaction [Cisplatin results in decreased activity of CS protein] |
CTD |
PMID:32860823 |
|
NCBI chr 7:1,348,389...1,374,624
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G |
Cxcr2 |
C-X-C motif chemokine receptor 2 |
multiple interactions |
EXP |
diphenyldiselenide inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of CXCR2 mRNA] |
CTD |
PMID:36174737 |
|
NCBI chr 9:75,729,493...75,735,868
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G |
Eno2 |
enolase 2 |
multiple interactions |
EXP |
diphenyldiselenide inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of ENO2 mRNA] |
CTD |
PMID:36174737 |
|
NCBI chr 4:159,258,371...159,267,220
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G |
G6pc1 |
glucose-6-phosphatase catalytic subunit 1 |
multiple interactions |
EXP |
diphenyldiselenide inhibits the reaction [acephate results in increased activity of G6PC1 protein]; diphenyldiselenide inhibits the reaction [Cisplatin results in increased activity of G6PC1 protein] |
CTD |
PMID:22778074 PMID:32860823 |
|
NCBI chr10:86,307,400...86,318,766
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|
G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
multiple interactions |
EXP |
diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of GCLC mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of GCLC protein] |
CTD |
PMID:33639173 |
|
NCBI chr 8:87,510,251...87,548,896
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G |
Gfap |
glial fibrillary acidic protein |
decreases expression multiple interactions |
EXP |
diphenyldiselenide results in decreased expression of GFAP protein diphenyldiselenide inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of GFAP mRNA] |
CTD |
PMID:19926633 PMID:36174737 |
|
NCBI chr10:88,352,987...88,361,661
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G |
Gpt |
glutamic--pyruvic transaminase |
multiple interactions increases activity |
EXP |
[diphenyldiselenide co-treated with diphenyldiselenide] promotes the reaction [Carbon Tetrachloride results in increased activity of GPT protein] diphenyldiselenide results in increased activity of GPT protein |
CTD |
PMID:17975852 PMID:18989868 |
|
NCBI chr 7:110,295,599...110,300,134
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|
G |
Gpx1 |
glutathione peroxidase 1 |
multiple interactions |
EXP |
diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA] |
CTD |
PMID:33639173 |
|
NCBI chr 8:117,905,462...117,906,588
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|
G |
Grin2a |
glutamate ionotropic receptor NMDA type subunit 2A |
multiple interactions |
ISO |
diphenyldiselenide inhibits the reaction [bisphenol A results in decreased expression of GRIN2A protein] |
CTD |
PMID:28572023 |
|
NCBI chr10:6,136,458...6,560,003
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|
G |
Grin2b |
glutamate ionotropic receptor NMDA type subunit 2B |
multiple interactions |
ISO |
diphenyldiselenide inhibits the reaction [bisphenol A results in decreased expression of GRIN2B protein] |
CTD |
PMID:28572023 |
|
NCBI chr 4:170,297,811...170,775,420
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|
G |
Hmox1 |
heme oxygenase 1 |
multiple interactions |
EXP |
diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; diphenyldiselenide promotes the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of HMOX1 mRNA] |
CTD |
PMID:33639173 PMID:36174737 |
|
NCBI chr19:13,452,365...13,479,823
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|
G |
Il10 |
interleukin 10 |
multiple interactions |
EXP |
diphenyldiselenide inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of IL10 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of IL10 protein] |
CTD |
PMID:33639173 PMID:36174737 |
|
NCBI chr13:45,024,921...45,029,586
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|
G |
Il1b |
interleukin 1 beta |
multiple interactions |
EXP |
diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of IL1B protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA] |
CTD |
PMID:33639173 |
|
NCBI chr 3:137,030,200...137,036,581
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|
G |
Il6 |
interleukin 6 |
multiple interactions |
EXP |
diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of IL6 protein] |
CTD |
PMID:33639173 |
|
NCBI chr 4:5,889,999...5,894,575
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|
G |
Keap1 |
Kelch-like ECH-associated protein 1 |
multiple interactions |
EXP |
diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of KEAP1 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of KEAP1 protein] |
CTD |
PMID:33639173 |
|
NCBI chr 8:19,768,375...19,777,862
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|
G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions decreases phosphorylation increases phosphorylation |
EXP ISO |
diphenyldiselenide inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein] diphenyldiselenide results in decreased phosphorylation of MAPK1 protein diphenyldiselenide results in increased phosphorylation of MAPK1 protein |
CTD |
PMID:20924558 PMID:33639173 |
|
NCBI chr11:97,462,025...97,529,193
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions decreases phosphorylation increases phosphorylation |
EXP ISO |
diphenyldiselenide inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein] diphenyldiselenide results in decreased phosphorylation of MAPK3 protein diphenyldiselenide results in increased phosphorylation of MAPK3 protein |
CTD |
PMID:20924558 PMID:33639173 |
|
NCBI chr 1:190,797,189...190,803,411
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|
G |
Mpo |
myeloperoxidase |
multiple interactions |
EXP |
diphenyldiselenide inhibits the reaction [Chlorpyrifos results in increased activity of MPO protein] |
CTD |
PMID:30267645 |
|
NCBI chr10:73,092,124...73,102,057
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|
G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions |
EXP |
diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; diphenyldiselenide promotes the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of NFE2L2 mRNA] |
CTD |
PMID:33639173 PMID:36174737 |
|
NCBI chr 3:81,001,529...81,031,165
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|
G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions |
EXP |
diphenyldiselenide inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of NFKB1 mRNA] |
CTD |
PMID:36174737 |
|
NCBI chr 2:226,689,745...226,805,897
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|
G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
EXP |
diphenyldiselenide inhibits the reaction [Streptozocin results in increased activity of NOS2 protein] |
CTD |
PMID:33639173 |
|
NCBI chr10:64,313,335...64,349,221
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|
G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
multiple interactions |
EXP |
diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of NQO1 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of NQO1 protein] |
CTD |
PMID:33639173 |
|
NCBI chr19:52,205,374...52,220,267
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|
G |
Slc17a7 |
solute carrier family 17 member 7 |
decreases expression |
EXP |
diphenyldiselenide results in decreased expression of SLC17A7 protein |
CTD |
PMID:19926633 |
|
NCBI chr 1:95,649,709...95,661,591
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|
G |
Slc1a1 |
solute carrier family 1 member 1 |
increases expression |
EXP |
diphenyldiselenide results in increased expression of SLC1A1 protein |
CTD |
PMID:19926633 |
|
NCBI chr 1:226,549,932...226,631,925
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|
G |
Slc1a3 |
solute carrier family 1 member 3 |
increases expression |
EXP |
diphenyldiselenide results in increased expression of SLC1A3 protein |
CTD |
PMID:19926633 |
|
NCBI chr 2:57,755,495...57,830,605
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|
G |
Slc2a2 |
solute carrier family 2 member 2 |
multiple interactions |
EXP |
diphenyldiselenide inhibits the reaction [Cisplatin results in increased expression of SLC2A2 protein] |
CTD |
PMID:32860823 |
|
NCBI chr 2:113,537,884...113,568,422
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|
G |
Snap25 |
synaptosome associated protein 25 |
decreases expression |
EXP |
diphenyldiselenide results in decreased expression of SNAP25 protein |
CTD |
PMID:19926633 |
|
NCBI chr 3:144,494,579...144,576,449
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|
G |
Tat |
tyrosine aminotransferase |
multiple interactions |
EXP |
diphenyldiselenide inhibits the reaction [acephate results in increased activity of TAT protein]; diphenyldiselenide inhibits the reaction [Cisplatin results in increased activity of TAT protein] |
CTD |
PMID:22778074 PMID:32860823 |
|
NCBI chr19:37,947,153...37,957,717
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|
G |
Tnf |
tumor necrosis factor |
multiple interactions |
EXP |
diphenyldiselenide inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of TNF mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of TNF protein] |
CTD |
PMID:33639173 PMID:36174737 |
|
NCBI chr20:3,626,685...3,629,303
|
|
G |
Txnrd1 |
thioredoxin reductase 1 |
decreases response to substance multiple interactions |
ISO |
TXNRD1 gene mutant form results in decreased susceptibility to diphenyldiselenide TXNRD1 gene mutant form inhibits the reaction [diphenyldiselenide results in increased abundance of Cysteine] diphenyldiselenide results in increased expression of and affects the localization of TXNRD1 protein |
CTD |
PMID:23360449 |
|
NCBI chr 7:22,717,620...22,802,553
|
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