|
G |
Abcc3 |
ATP binding cassette subfamily C member 3 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of ABCC3 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr10:79,793,571...79,839,528
|
|
G |
Abhd12b |
abhydrolase domain containing 12B |
increases expression |
ISO |
cinnamaldehyde results in increased expression of ABHD12B mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 6:88,668,627...88,696,435
|
|
G |
Acta2 |
actin alpha 2, smooth muscle |
multiple interactions |
EXP |
cinnamaldehyde inhibits the reaction [Glucose results in increased expression of ACTA2 protein] |
CTD |
PMID:20060012 |
|
NCBI chr 1:241,159,723...241,172,503
|
|
G |
Actb |
actin, beta |
increases metabolic processing |
ISO |
cinnamaldehyde results in increased metabolism of ACTB protein |
CTD |
PMID:29267982 |
|
NCBI chr12:16,776,664...16,779,634
|
|
G |
Adam23 |
ADAM metallopeptidase domain 23 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of ADAM23 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 9:64,862,649...65,009,718
|
|
G |
Adk |
adenosine kinase |
increases expression |
ISO |
cinnamaldehyde results in increased expression of ADK mRNA |
CTD |
PMID:19524605 |
|
NCBI chr15:2,912,543...3,295,745
|
|
G |
Adm |
adrenomedullin |
increases expression |
ISO |
cinnamaldehyde results in increased expression of ADM mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 1:174,164,178...174,182,372
|
|
G |
Ager |
advanced glycosylation end product-specific receptor |
multiple interactions |
EXP |
cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of AGER protein] |
CTD |
PMID:33522063 |
|
NCBI chr20:4,152,758...4,155,956
|
|
G |
Akr1b10 |
aldo-keto reductase family 1 member B10 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of AKR1B10 mRNA |
CTD |
PMID:30806763 |
|
NCBI chr 4:64,005,632...64,027,860
|
|
G |
Akr1c1 |
aldo-keto reductase family 1, member C1 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of AKR1C1 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr17:70,720,397...70,747,285
|
|
G |
Akr1c2 |
aldo-keto reductase family 1, member C2 |
increases activity multiple interactions increases expression |
ISO |
cinnamaldehyde results in increased activity of AKR1C2 promoter NFE2L2 mRNA promotes the reaction [cinnamaldehyde results in increased expression of AKR1C2 mRNA] |
CTD |
PMID:21195160 PMID:25724174 PMID:26244607 |
|
NCBI chr17:70,669,684...70,717,935
|
|
G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions increases phosphorylation |
ISO |
cinnamaldehyde inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of AKT1 protein] cinnamaldehyde results in increased phosphorylation of AKT1 protein |
CTD |
PMID:20467561 PMID:21469739 |
|
NCBI chr 6:137,534,810...137,555,131
|
|
G |
Alb |
albumin |
increases metabolic processing |
ISO |
cinnamaldehyde results in increased metabolism of ALB protein |
CTD |
PMID:29267982 |
|
NCBI chr14:17,891,564...17,907,043
|
|
G |
Als2 |
alsin Rho guanine nucleotide exchange factor ALS2 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of ALS2 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 9:68,107,310...68,180,192
|
|
G |
Ampd3 |
adenosine monophosphate deaminase 3 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of AMPD3 mRNA |
CTD |
PMID:24211530 |
|
NCBI chr 1:164,884,823...164,929,899
|
|
G |
Arhgap23 |
Rho GTPase activating protein 23 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of ARHGAP23 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr10:82,891,021...82,993,230
|
|
G |
Atf3 |
activating transcription factor 3 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of ATF3 mRNA |
CTD |
PMID:23999411 PMID:27965148 |
|
NCBI chr13:105,274,103...105,331,653
|
|
G |
Atp11a |
ATPase phospholipid transporting 11A |
increases expression |
ISO |
cinnamaldehyde results in increased expression of ATP11A mRNA |
CTD |
PMID:19524605 |
|
NCBI chr16:76,657,752...76,767,640
|
|
G |
B2m |
beta-2 microglobulin |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of B2M mRNA |
CTD |
PMID:28219650 |
|
NCBI chr 3:129,549,236...129,555,354
|
|
G |
Bach1 |
BTB domain and CNC homolog 1 |
multiple interactions |
ISO |
BACH1 mRNA promotes the reaction [cinnamaldehyde results in increased expression of HMOX1 mRNA] |
CTD |
PMID:26244607 |
|
NCBI chr11:40,425,721...40,461,118
|
|
G |
Bax |
BCL2 associated X, apoptosis regulator |
increases expression multiple interactions |
ISO EXP |
cinnamaldehyde results in increased expression of BAX protein cinnamaldehyde inhibits the reaction [Testosterone results in decreased expression of BAX mRNA] Vitamin E inhibits the reaction [cinnamaldehyde results in increased expression of BAX protein] |
CTD |
PMID:15566391 PMID:15964311 PMID:32628957 |
|
NCBI chr 1:105,076,472...105,081,906
|
|
G |
Bcap29 |
B-cell receptor-associated protein 29 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of BCAP29 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 6:48,182,702...48,222,698
|
|
G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions decreases expression |
ISO EXP |
Vitamin E inhibits the reaction [cinnamaldehyde results in decreased expression of BCL2 protein] cinnamaldehyde inhibits the reaction [Testosterone results in increased expression of BCL2 mRNA] cinnamaldehyde analog results in decreased expression of BCL2 protein; cinnamaldehyde results in decreased expression of BCL2 protein |
CTD |
PMID:15566391 PMID:15964311 PMID:17510524 PMID:32628957 |
|
NCBI chr13:23,204,464...23,366,900
|
|
G |
Bid |
BH3 interacting domain death agonist |
increases cleavage |
ISO |
cinnamaldehyde results in increased cleavage of BID protein |
CTD |
PMID:15964311 |
|
NCBI chr 4:155,785,366...155,808,775
|
|
G |
Birc2 |
baculoviral IAP repeat-containing 2 |
decreases expression multiple interactions |
ISO |
cinnamaldehyde results in decreased expression of BIRC2 protein Vitamin E inhibits the reaction [cinnamaldehyde results in decreased expression of BIRC2 protein] |
CTD |
PMID:15566391 |
|
NCBI chr 8:13,253,697...13,273,672
|
|
G |
Birc3 |
baculoviral IAP repeat-containing 3 |
multiple interactions decreases expression |
ISO |
Vitamin E inhibits the reaction [cinnamaldehyde results in decreased expression of BIRC3 protein] |
CTD |
PMID:15566391 |
|
NCBI chr 8:13,285,702...13,313,329
|
|
G |
Casp1 |
caspase 1 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of CASP1 mRNA |
CTD |
PMID:19000754 |
|
NCBI chr 8:10,746,338...10,882,295
|
|
G |
Casp3 |
caspase 3 |
multiple interactions increases activity increases cleavage increases expression |
ISO |
Vitamin E inhibits the reaction [cinnamaldehyde results in increased activity of CASP3 protein] cinnamaldehyde analog results in increased activity of CASP3 protein; cinnamaldehyde results in increased activity of CASP3 protein cinnamaldehyde results in increased cleavage of CASP3 protein cinnamaldehyde analog results in increased expression of CASP3 protein |
CTD |
PMID:15566391 PMID:16343908 PMID:17510524 PMID:19000754 |
|
NCBI chr16:52,395,539...52,413,794
|
|
G |
Casp8 |
caspase 8 |
increases activity |
ISO |
cinnamaldehyde results in increased activity of CASP8 protein |
CTD |
PMID:15964311 |
|
NCBI chr 9:67,747,109...67,806,699
|
|
G |
Casp9 |
caspase 9 |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of CASP9 mRNA |
CTD |
PMID:28219650 |
|
|
|
G |
Cat |
catalase |
multiple interactions decreases activity increases expression |
ISO EXP |
NFE2L2 protein promotes the reaction [cinnamaldehyde results in increased expression of CAT mRNA] cinnamaldehyde results in decreased activity of CAT protein cinnamaldehyde inhibits the reaction [Cisplatin results in decreased activity of CAT protein] |
CTD |
PMID:17076691 PMID:23959918 PMID:28219650 |
|
NCBI chr 3:110,297,340...110,329,526
|
|
G |
Ccdc34 |
coiled-coil domain containing 34 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of CCDC34 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 3:96,553,074...96,588,310
|
|
G |
Ccl20 |
C-C motif chemokine ligand 20 |
increases expression affects expression |
ISO |
cinnamaldehyde results in increased expression of CCL20 mRNA cinnamaldehyde affects the expression of CCL20 mRNA |
CTD |
PMID:28219650 PMID:30806763 |
|
NCBI chr 9:91,837,139...91,839,736
|
|
G |
Ccl22 |
C-C motif chemokine ligand 22 |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of CCL22 mRNA |
CTD |
PMID:28219650 |
|
NCBI chr19:10,263,589...10,270,359
|
|
G |
Ccl3 |
C-C motif chemokine ligand 3 |
affects expression increases secretion multiple interactions |
ISO |
cinnamaldehyde affects the expression of CCL3 mRNA cinnamaldehyde results in increased secretion of CCL3 protein NFE2L2 protein inhibits the reaction [cinnamaldehyde results in increased expression of CCL3 mRNA] |
CTD |
PMID:23624239 PMID:28219650 |
|
NCBI chr10:68,948,889...68,950,439
|
|
G |
Ccl4 |
C-C motif chemokine ligand 4 |
affects expression increases secretion |
ISO |
cinnamaldehyde affects the expression of CCL4 mRNA cinnamaldehyde results in increased secretion of CCL4 protein |
CTD |
PMID:28219650 PMID:30806763 |
|
NCBI chr10:68,963,893...68,965,728
|
|
G |
Ccl5 |
C-C motif chemokine ligand 5 |
increases secretion decreases expression |
ISO |
cinnamaldehyde results in increased secretion of CCL5 protein cinnamaldehyde results in decreased expression of CCL5 mRNA |
CTD |
PMID:20488241 PMID:28219650 |
|
NCBI chr10:68,820,330...68,824,906
|
|
G |
Ccn2 |
cellular communication network factor 2 |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of CCN2 mRNA |
CTD |
PMID:17178418 |
|
NCBI chr 1:22,621,498...22,624,614
|
|
G |
Ccnd1 |
cyclin D1 |
multiple interactions |
EXP |
cinnamaldehyde inhibits the reaction [Testosterone results in increased expression of CCND1 protein] |
CTD |
PMID:32628957 |
|
NCBI chr 1:209,518,288...209,527,986
|
|
G |
Cd274 |
CD274 molecule |
increases expression |
ISO |
cinnamaldehyde results in increased expression of CD274 protein |
CTD |
PMID:20488241 PMID:23624239 |
|
NCBI chr 1:236,526,215...236,549,956
|
|
G |
Cd80 |
Cd80 molecule |
increases expression |
ISO |
cinnamaldehyde results in increased expression of CD80 mRNA |
CTD |
PMID:28219650 |
|
NCBI chr11:75,760,073...75,798,978
|
|
G |
Cd83 |
CD83 molecule |
decreases expression increases expression |
ISO |
cinnamaldehyde results in decreased expression of CD83 mRNA cinnamaldehyde results in increased expression of CD83 mRNA |
CTD |
PMID:27196738 PMID:28219650 |
|
NCBI chr17:21,093,281...21,113,223
|
|
G |
Cd86 |
CD86 molecule |
decreases expression increases expression |
ISO |
cinnamaldehyde results in decreased expression of CD86 mRNA cinnamaldehyde results in increased expression of CD86 protein cinnamaldehyde results in increased expression of CD86 mRNA; cinnamaldehyde results in increased expression of CD86 protein |
CTD |
PMID:11244134 PMID:19524605 PMID:19665512 PMID:20488241 PMID:23624239 PMID:28219650 PMID:30806763 More...
|
|
NCBI chr11:77,647,565...77,706,178
|
|
G |
Cdc25b |
cell division cycle 25B |
decreases activity |
ISO |
cinnamaldehyde analog results in decreased activity of CDC25B protein |
CTD |
PMID:16343908 |
|
NCBI chr 3:138,860,148...138,870,287
|
|
G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression |
ISO |
cinnamaldehyde results in increased expression of CDKN1A mRNA; cinnamaldehyde results in increased expression of CDKN1A protein |
CTD |
PMID:19000754 |
|
NCBI chr20:7,150,820...7,161,373
|
|
G |
Cebpa |
CCAAT/enhancer binding protein alpha |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of CEBPA mRNA |
CTD |
PMID:21401097 |
|
NCBI chr 1:87,759,631...87,762,303
|
|
G |
Ces1d |
carboxylesterase 1D |
increases expression |
ISO |
cinnamaldehyde results in increased expression of CES1 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr19:30,046,494...30,085,039
|
|
G |
Chuk |
component of inhibitor of nuclear factor kappa B kinase complex |
decreases phosphorylation |
EXP |
cinnamaldehyde results in decreased phosphorylation of CHUK protein |
CTD |
PMID:17486422 |
|
NCBI chr 1:252,908,748...252,944,273
|
|
G |
Clec4a3 |
C-type lectin domain family 4, member A3 |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of CLEC4A protein |
CTD |
PMID:23624239 |
|
NCBI chr 4:156,214,030...156,224,818
|
|
G |
Clk2 |
CDC-like kinase 2 |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of CLK2 mRNA |
CTD |
PMID:17178418 |
|
NCBI chr 2:176,868,423...176,880,412
|
|
G |
Cnot2 |
CCR4-NOT transcription complex, subunit 2 |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of CNOT2 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 7:52,130,445...52,222,338
|
|
G |
Col7a1 |
collagen type VII alpha 1 chain |
increases expression |
ISO |
cinnamaldehyde results in increased expression of COL7A1 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 8:109,604,877...109,637,249
|
|
G |
Creb1 |
cAMP responsive element binding protein 1 |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of CREB1 mRNA |
CTD |
PMID:20385217 |
|
NCBI chr 9:73,397,333...73,466,339
|
|
G |
Crem |
cAMP responsive element modulator |
increases expression |
ISO |
cinnamaldehyde results in increased expression of CREM mRNA |
CTD |
PMID:19524605 |
|
NCBI chr17:58,932,011...59,001,160
|
|
G |
Crim1 |
cysteine rich transmembrane BMP regulator 1 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of CRIM1 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 6:16,695,864...16,870,264
|
|
G |
Crkl |
CRK like proto-oncogene, adaptor protein |
decreases phosphorylation |
ISO |
cinnamaldehyde results in decreased phosphorylation of CRKL protein |
CTD |
PMID:21729535 |
|
NCBI chr11:97,033,033...97,067,457
|
|
G |
Cxcl1 |
C-X-C motif chemokine ligand 1 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of CXCL1 mRNA |
CTD |
PMID:30806763 |
|
NCBI chr14:17,477,542...17,479,321
|
|
G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
increases expression multiple interactions |
ISO |
cinnamaldehyde results in increased expression of CXCL10 mRNA NFE2L2 protein inhibits the reaction [cinnamaldehyde results in increased expression of CXCL10 mRNA] |
CTD |
PMID:28219650 |
|
NCBI chr14:15,989,066...15,991,263
|
|
G |
Cxcl14 |
C-X-C motif chemokine ligand 14 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of CXCL14 mRNA |
CTD |
PMID:30806763 |
|
NCBI chr17:8,323,150...8,331,176
|
|
G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
increases expression multiple interactions affects expression |
ISO |
cinnamaldehyde results in increased expression of CXCL1 mRNA NFE2L2 protein inhibits the reaction [cinnamaldehyde results in increased expression of CXCL1 mRNA] cinnamaldehyde affects the expression of CXCL1 mRNA |
CTD |
PMID:28219650 PMID:30806763 |
|
NCBI chr14:17,571,900...17,573,624
|
|
G |
Cxcr1 |
C-X-C motif chemokine receptor 1 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of CXCR1 mRNA |
CTD |
PMID:30806763 |
|
NCBI chr 9:83,216,040...83,220,225
|
|
G |
Cxcr4 |
C-X-C motif chemokine receptor 4 |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of CXCR4 mRNA |
CTD |
PMID:28219650 |
|
NCBI chr13:42,630,383...42,634,288
|
|
G |
Cycs |
cytochrome c, somatic |
multiple interactions affects localization |
ISO |
Vitamin E inhibits the reaction [cinnamaldehyde affects the localization of CYCS protein] |
CTD |
PMID:15566391 |
|
NCBI chr 4:80,982,667...80,984,767
|
|
G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of CYP1A1 mRNA |
CTD |
PMID:30806763 |
|
NCBI chr 8:66,991,940...66,998,014
|
|
G |
Cyp7a1 |
cytochrome P450 family 7 subfamily A member 1 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of CYP7A1 mRNA |
CTD |
PMID:19000754 |
|
NCBI chr 5:24,174,505...24,184,202
|
|
G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of DDIT3 mRNA |
CTD |
PMID:19000754 |
|
NCBI chr 7:65,001,695...65,006,517
|
|
G |
Ddit4 |
DNA-damage-inducible transcript 4 |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of DDIT4 mRNA |
CTD |
PMID:17178418 |
|
NCBI chr20:28,434,938...28,437,037
|
|
G |
Diablo |
diablo, IAP-binding mitochondrial protein |
affects localization multiple interactions |
ISO |
cinnamaldehyde affects the localization of DIABLO protein Vitamin E inhibits the reaction [cinnamaldehyde affects the localization of DIABLO protein] |
CTD |
PMID:15566391 |
|
NCBI chr12:38,716,668...38,731,285
|
|
G |
Dmtn |
dematin actin binding protein |
increases expression |
ISO |
cinnamaldehyde results in increased expression of DMTN mRNA |
CTD |
PMID:19524605 |
|
NCBI chr15:45,677,974...45,702,261
|
|
G |
Dnajb4 |
DnaJ heat shock protein family (Hsp40) member B4 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of DNAJB4 mRNA |
CTD |
PMID:23999411 PMID:27965148 |
|
NCBI chr 2:243,790,296...243,819,042
|
|
G |
Dnmt3b |
DNA methyltransferase 3 beta |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of DNMT3B mRNA |
CTD |
PMID:17178418 |
|
NCBI chr 3:142,130,588...142,169,128
|
|
G |
Dusp1 |
dual specificity phosphatase 1 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of DUSP1 mRNA |
CTD |
PMID:30806763 |
|
NCBI chr10:17,184,853...17,187,646
|
|
G |
Dusp6 |
dual specificity phosphatase 6 |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of DUSP6 mRNA |
CTD |
PMID:17178418 |
|
NCBI chr 7:35,979,502...35,983,834
|
|
G |
Dynlrb1 |
dynein light chain roadblock-type 1 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of DYNLRB1 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 3:143,742,427...143,764,227
|
|
G |
Eaf2 |
ELL associated factor 2 |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of EAF2 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr11:63,960,200...64,004,610
|
|
G |
Egr1 |
early growth response 1 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of EGR1 mRNA |
CTD |
PMID:19000754 |
|
NCBI chr18:26,737,078...26,740,877
|
|
G |
Eif3a |
eukaryotic translation initiation factor 3, subunit A |
increases metabolic processing |
ISO |
cinnamaldehyde results in increased metabolism of EIF3A protein |
CTD |
PMID:29267982 |
|
NCBI chr 1:269,888,730...269,925,785
|
|
G |
Epas1 |
endothelial PAS domain protein 1 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of EPAS1 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 6:13,543,252...13,626,147
|
|
G |
F2rl1 |
F2R like trypsin receptor 1 |
multiple interactions |
ISO |
edelfosine inhibits the reaction [F2RL1 protein promotes the reaction [cinnamaldehyde results in increased activity of TRPA1 protein]]; F2RL1 protein promotes the reaction [cinnamaldehyde results in increased activity of TRPA1 protein] |
CTD |
PMID:17571167 |
|
NCBI chr 2:28,507,003...28,519,954
|
|
G |
Fabp4 |
fatty acid binding protein 4 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of FABP4 mRNA |
CTD |
PMID:30806763 |
|
NCBI chr 2:93,488,251...93,492,961
|
|
G |
Fas |
Fas cell surface death receptor |
multiple interactions decreases expression |
ISO |
dorsomorphin inhibits the reaction [cinnamaldehyde results in decreased expression of FAS mRNA] |
CTD |
PMID:21401097 |
|
NCBI chr 1:241,212,155...241,245,774
|
|
G |
Fcgr2b |
Fc gamma receptor 2B |
increases expression |
ISO |
cinnamaldehyde results in increased expression of FCGR2B mRNA |
CTD |
PMID:19524605 |
|
NCBI chr13:85,725,897...85,740,517
|
|
G |
Fgfr2 |
fibroblast growth factor receptor 2 |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of FGFR2 mRNA |
CTD |
PMID:17178418 |
|
NCBI chr 1:194,175,703...194,280,914
|
|
G |
Fmo5 |
flavin containing dimethylaniline monoxygenase 5 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of FMO5 mRNA |
CTD |
PMID:19000754 |
|
NCBI chr 2:185,197,184...185,249,699
|
|
G |
Fn1 |
fibronectin 1 |
multiple interactions |
EXP |
cinnamaldehyde inhibits the reaction [Glucose results in increased expression of FN1 protein] |
CTD |
PMID:20060012 |
|
NCBI chr 9:80,645,507...80,714,200
|
|
G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
decreases expression |
ISO |
cinnamaldehyde analog results in decreased expression of FOS protein |
CTD |
PMID:17510524 |
|
NCBI chr 6:110,852,188...110,855,054
|
|
G |
Fth1 |
ferritin heavy chain 1 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of FTH1 mRNA |
CTD |
PMID:19524605 PMID:24211530 |
|
NCBI chr 1:216,052,037...216,054,325
|
|
G |
Ftl1 |
ferritin light chain 1 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of FTL mRNA |
CTD |
PMID:24211530 |
|
NCBI chr 1:105,072,858...105,074,705
|
|
G |
Fzd2 |
frizzled class receptor 2 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of FZD2 mRNA |
CTD |
PMID:17178418 |
|
NCBI chr10:88,061,988...88,063,898
|
|
G |
G6pd |
glucose-6-phosphate dehydrogenase |
increases expression |
ISO |
cinnamaldehyde results in increased expression of G6PD mRNA |
CTD |
PMID:19524605 |
|
NCBI chr X:157,352,364...157,372,144
|
|
G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
increases expression multiple interactions |
ISO |
cinnamaldehyde results in increased expression of GCLC mRNA; cinnamaldehyde results in increased expression of GCLC protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [cinnamaldehyde results in increased expression of GCLC protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cinnamaldehyde results in increased expression of GCLC protein]; [cinnamaldehyde results in increased activity of NFE2L2 protein] which results in increased expression of GCLC mRNA; NFE2L2 mRNA affects the reaction [cinnamaldehyde results in increased expression of GCLC protein]; pyrazolanthrone inhibits the reaction [cinnamaldehyde results in increased expression of GCLC protein] |
CTD |
PMID:17178418 PMID:20351055 PMID:21469739 PMID:30806763 |
|
NCBI chr 8:87,510,251...87,548,896
|
|
G |
Gclm |
glutamate cysteine ligase, modifier subunit |
increases expression multiple interactions |
ISO |
cinnamaldehyde results in increased expression of GCLM mRNA [cinnamaldehyde results in increased activity of NFE2L2 protein] which results in increased expression of GCLM mRNA |
CTD |
PMID:17178418 PMID:20351055 PMID:23999411 PMID:24211530 PMID:27965148 PMID:30806763 More...
|
|
NCBI chr 2:213,032,135...213,052,192
|
|
G |
Glrx |
glutaredoxin |
increases expression increases activity multiple interactions |
ISO |
cinnamaldehyde results in increased expression of GLRX mRNA cinnamaldehyde results in increased activity of GLRX protein [Cadmium Chloride affects the activity of GLRX protein] inhibits the reaction [cinnamaldehyde results in increased glutathionylation of RELA protein]; [cinnamaldehyde results in increased activity of GLRX protein] inhibits the reaction [TNF protein affects the localization of RELA protein]; [cinnamaldehyde results in increased activity of GLRX protein] inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; [cinnamaldehyde results in increased activity of GLRX protein] which results in increased glutathionylation of RELA protein |
CTD |
PMID:20351055 |
|
NCBI chr 2:5,341,873...5,351,686
|
|
G |
Gpr21 |
G protein-coupled receptor 21 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of GPR21 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 3:21,275,289...21,279,008
|
|
G |
Gpx1 |
glutathione peroxidase 1 |
multiple interactions affects expression |
ISO |
NFE2L2 protein promotes the reaction [cinnamaldehyde results in increased expression of GPX1 mRNA] cinnamaldehyde affects the expression of GPX1 mRNA |
CTD |
PMID:28219650 |
|
NCBI chr 8:117,905,462...117,906,588
|
|
G |
Gpx2 |
glutathione peroxidase 2 |
multiple interactions increases expression affects expression |
ISO |
NFE2L2 protein promotes the reaction [cinnamaldehyde results in increased expression of GPX2 mRNA] cinnamaldehyde affects the expression of GPX2 mRNA |
CTD |
PMID:19000754 PMID:28219650 |
|
NCBI chr 6:101,226,745...101,230,033
|
|
G |
Gpx5 |
glutathione peroxidase 5 |
affects expression multiple interactions |
ISO |
cinnamaldehyde affects the expression of GPX5 mRNA NFE2L2 protein promotes the reaction [cinnamaldehyde results in increased expression of GPX5 mRNA] |
CTD |
PMID:28219650 |
|
NCBI chr17:43,436,126...43,443,074
|
|
G |
Gpx6 |
glutathione peroxidase 6 |
affects expression multiple interactions |
ISO |
cinnamaldehyde affects the expression of GPX6 mRNA NFE2L2 protein promotes the reaction [cinnamaldehyde results in increased expression of GPX6 mRNA] |
CTD |
PMID:28219650 |
|
NCBI chr17:43,408,472...43,416,091
|
|
G |
Gpx7 |
glutathione peroxidase 7 |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of GPX7 mRNA |
CTD |
PMID:28219650 |
|
NCBI chr 5:123,145,151...123,153,141
|
|
G |
Gsk3b |
glycogen synthase kinase 3 beta |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of GSK3B mRNA |
CTD |
PMID:28219650 |
|
NCBI chr11:76,004,502...76,154,665
|
|
G |
Gsr |
glutathione-disulfide reductase |
increases expression multiple interactions |
ISO |
cinnamaldehyde results in increased expression of GSR mRNA NFE2L2 protein promotes the reaction [cinnamaldehyde results in increased expression of GSR mRNA] |
CTD |
PMID:19000754 PMID:28219650 |
|
NCBI chr16:65,185,574...65,228,742
|
|
G |
Gstm1 |
glutathione S-transferase mu 1 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of GSTM1 mRNA |
CTD |
PMID:28219650 |
|
NCBI chr 2:198,338,005...198,346,007
|
|
G |
Gstp1 |
glutathione S-transferase pi 1 |
multiple interactions |
ISO |
cinnamaldehyde binds to and results in decreased activity of GSTP1 protein |
CTD |
PMID:9463521 |
|
NCBI chr 1:210,767,237...210,770,242
|
|
G |
Gstt1 |
glutathione S-transferase theta 1 |
affects expression |
ISO |
cinnamaldehyde affects the expression of GSTT1 mRNA |
CTD |
PMID:28219650 |
|
NCBI chr20:12,856,068...12,873,020
|
|
G |
Hbb |
hemoglobin subunit beta |
increases metabolic processing |
ISO |
cinnamaldehyde results in increased metabolism of HBB protein |
CTD |
PMID:29267982 |
|
NCBI chr 1:167,662,310...167,663,721
|
|
G |
Hfe |
homeostatic iron regulator |
increases expression |
ISO |
cinnamaldehyde results in increased expression of HFE mRNA |
CTD |
PMID:19524605 |
|
NCBI chr17:41,841,302...41,849,359
|
|
G |
Hist1h4m |
histone cluster 1, H4m |
increases metabolic processing |
ISO |
cinnamaldehyde results in increased metabolism of H4C1 protein |
CTD |
PMID:29267982 |
|
NCBI chr17:47,393,764...47,394,168
|
|
G |
Hmgb1 |
high mobility group box 1 |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of HMGB1 mRNA |
CTD |
PMID:28219650 |
|
NCBI chr12:11,009,236...11,015,941
|
|
G |
Hmox1 |
heme oxygenase 1 |
increases expression multiple interactions |
ISO |
cinnamaldehyde results in increased expression of HMOX1 mRNA cinnamaldehyde inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of HMOX1 protein] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [cinnamaldehyde results in increased expression of HMOX1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cinnamaldehyde results in increased expression of HMOX1 protein]; [ethylhexadecyldimethylammonium co-treated with cinnamaldehyde] results in increased expression of HMOX1 mRNA; [ethylhexadecyldimethylammonium co-treated with cinnamaldehyde] results in increased expression of HMOX1 protein; BACH1 mRNA promotes the reaction [cinnamaldehyde results in increased expression of HMOX1 mRNA]; NFE2L2 mRNA promotes the reaction [cinnamaldehyde results in increased expression of HMOX1 mRNA]; pyrazolanthrone inhibits the reaction [cinnamaldehyde results in increased expression of HMOX1 protein] cinnamaldehyde analog results in increased expression of HMOX1 mRNA; cinnamaldehyde analog results in increased expression of HMOX1 protein; cinnamaldehyde results in increased expression of HMOX1 mRNA; cinnamaldehyde results in increased expression of HMOX1 protein |
CTD |
PMID:17178418 PMID:18304597 PMID:18482591 PMID:19000754 PMID:19033392 PMID:20713136 PMID:21469739 PMID:24211530 PMID:25724174 PMID:26244607 PMID:28219650 PMID:30806763 PMID:31187328 PMID:37089166 More...
|
|
NCBI chr19:13,452,365...13,479,823
|
|
G |
Hnrnpk |
heterogeneous nuclear ribonucleoprotein K |
increases metabolic processing |
ISO |
cinnamaldehyde results in increased metabolism of HNRNPK protein |
CTD |
PMID:29267982 |
|
NCBI chr17:6,269,302...6,280,429
|
|
G |
Hprt1 |
hypoxanthine phosphoribosyltransferase 1 |
decreases mutagenesis |
ISO |
cinnamaldehyde results in decreased mutagenesis of HPRT1 gene |
CTD |
PMID:17178418 |
|
NCBI chr X:132,736,175...132,768,149
|
|
G |
Hsp90aa1 |
heat shock protein 90 alpha family class A member 1 |
increases metabolic processing |
ISO |
cinnamaldehyde results in increased metabolism of HSP90AA1 protein |
CTD |
PMID:29267982 |
|
NCBI chr 6:135,523,604...135,529,687
|
|
G |
Hspa1b |
heat shock protein family A (Hsp70) member 1B |
increases expression |
ISO |
cinnamaldehyde results in increased expression of HSPA1B mRNA |
CTD |
PMID:17178418 |
|
NCBI chr20:3,859,756...3,863,800
|
|
G |
Hspa6l-ps1 |
heat shock protein family A (Hsp70) member 6 like, pseudogene 1 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of HSPA6 mRNA |
CTD |
PMID:23999411 |
|
NCBI chr13:85,805,911...85,807,052
|
|
G |
Hspa8 |
heat shock protein family A (Hsp70) member 8 |
increases metabolic processing |
ISO |
cinnamaldehyde results in increased metabolism of HSPA8 protein |
CTD |
PMID:29267982 |
|
NCBI chr 8:50,080,514...50,084,376
|
|
G |
Hsph1 |
heat shock protein family H (Hsp110) member 1 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of HSPH1 mRNA |
CTD |
PMID:23999411 |
|
NCBI chr12:5,390,916...5,410,224
|
|
G |
Htatip2 |
HIV-1 Tat interactive protein 2 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of HTATIP2 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 1:108,609,424...108,624,810
|
|
G |
Htra2 |
HtrA serine peptidase 2 |
affects localization multiple interactions |
ISO |
cinnamaldehyde affects the localization of HTRA2 protein Vitamin E inhibits the reaction [cinnamaldehyde affects the localization of HTRA2 protein] |
CTD |
PMID:15566391 |
|
NCBI chr 4:117,114,631...117,117,793
|
|
G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions increases expression |
ISO EXP |
[cinnamaldehyde results in increased activity of GLRX protein] inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; [cinnamaldehyde results in increased activity of NFE2L2 protein] inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; Buthionine Sulfoximine inhibits the reaction [cinnamaldehyde inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]; cinnamaldehyde inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein] cinnamaldehyde results in increased expression of ICAM1 mRNA; cinnamaldehyde results in increased expression of ICAM1 protein |
CTD |
PMID:20351055 PMID:30806763 PMID:33522063 |
|
NCBI chr 8:27,829,688...27,841,618
|
|
G |
Ifi27 |
interferon, alpha-inducible protein 27 |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of IFI27 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 6:122,590,461...122,596,996
|
|
G |
Ifi44l |
interferon-induced protein 44-like |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of IFI44L mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 2:243,328,629...243,366,404
|
|
G |
Ifnb1 |
interferon beta 1 |
multiple interactions |
ISO |
cinnamaldehyde inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA] |
CTD |
PMID:17920563 |
|
NCBI chr 5:108,066,650...108,067,487
|
|
G |
Ifng |
interferon gamma |
increases expression affects expression |
ISO |
cinnamaldehyde results in increased expression of IFNG protein cinnamaldehyde affects the expression of IFNG mRNA |
CTD |
PMID:11244134 PMID:28219650 |
|
NCBI chr 7:55,789,180...55,793,216
|
|
G |
Ikbkb |
inhibitor of nuclear factor kappa B kinase subunit beta |
decreases phosphorylation |
EXP |
cinnamaldehyde results in decreased phosphorylation of IKBKB protein |
CTD |
PMID:17486422 |
|
NCBI chr16:76,021,968...76,075,717
|
|
G |
Il10 |
interleukin 10 |
affects expression |
ISO |
cinnamaldehyde affects the expression of IL10 mRNA |
CTD |
PMID:28219650 |
|
NCBI chr13:45,024,921...45,029,586
|
|
G |
Il12a |
interleukin 12A |
multiple interactions affects expression |
ISO |
NFE2L2 protein inhibits the reaction [cinnamaldehyde results in increased expression of IL12A mRNA] cinnamaldehyde affects the expression of IL12A mRNA |
CTD |
PMID:28219650 |
|
NCBI chr 2:155,275,734...155,282,997
|
|
G |
Il12b |
interleukin 12B |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of IL12B mRNA |
CTD |
PMID:28219650 |
|
NCBI chr10:29,390,300...29,405,194
|
|
G |
Il16 |
interleukin 16 |
increases secretion multiple interactions |
ISO |
cinnamaldehyde results in increased secretion of IL16 protein cinnamaldehyde results in increased expression of and results in increased secretion of IL16 protein |
CTD |
PMID:23624239 PMID:30806763 |
|
NCBI chr 1:137,617,702...137,718,022
|
|
G |
Il18 |
interleukin 18 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of IL18 mRNA; cinnamaldehyde results in increased expression of IL18 protein |
CTD |
PMID:23063874 PMID:30806763 |
|
NCBI chr 8:59,802,072...59,829,275
|
|
G |
Il1a |
interleukin 1 alpha |
increases expression multiple interactions |
ISO |
cinnamaldehyde results in increased expression of IL1A mRNA [ethylhexadecyldimethylammonium co-treated with cinnamaldehyde] results in increased expression of IL1A mRNA; [NFE2L2 protein affects the susceptibility to cinnamaldehyde] which affects the expression of IL1A mRNA; NFE2L2 protein affects the reaction [[ethylhexadecyldimethylammonium co-treated with cinnamaldehyde] results in increased expression of IL1A mRNA] |
CTD |
PMID:25290854 PMID:28219650 PMID:30806763 PMID:33715048 PMID:37089166 |
|
NCBI chr 3:136,979,804...136,990,236
|
|
G |
Il1b |
interleukin 1 beta |
multiple interactions increases expression |
ISO EXP |
[ethylhexadecyldimethylammonium co-treated with cinnamaldehyde] results in increased expression of IL1B mRNA; [NFE2L2 protein affects the susceptibility to cinnamaldehyde] which affects the expression of IL1B mRNA; cinnamaldehyde inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein]; NFE2L2 protein affects the reaction [[ethylhexadecyldimethylammonium co-treated with cinnamaldehyde] results in increased expression of IL1B mRNA] cinnamaldehyde inhibits the reaction [IL1B protein results in increased abundance of Dinoprostone]; cinnamaldehyde inhibits the reaction [IL1B protein results in increased activity of PTGS2 protein]; cinnamaldehyde inhibits the reaction [Testosterone results in increased expression of IL1B protein] cinnamaldehyde results in increased expression of IL1B mRNA cinnamaldehyde inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; NFE2L2 protein inhibits the reaction [cinnamaldehyde results in increased expression of IL1B mRNA] |
CTD |
PMID:16624280 PMID:19524605 PMID:20467561 PMID:21807015 PMID:28219650 PMID:32628957 PMID:33715048 PMID:37089166 More...
|
|
NCBI chr 3:137,030,200...137,036,581
|
|
G |
Il23a |
interleukin 23 subunit alpha |
multiple interactions |
ISO |
[NFE2L2 protein affects the susceptibility to cinnamaldehyde] which affects the expression of IL23A mRNA; NFE2L2 protein affects the reaction [[ethylhexadecyldimethylammonium co-treated with cinnamaldehyde] results in increased expression of IL23A mRNA] |
CTD |
PMID:37089166 |
|
NCBI chr 7:1,306,320...1,308,434
|
|
G |
Il24 |
interleukin 24 |
multiple interactions |
ISO |
[NFE2L2 protein affects the susceptibility to cinnamaldehyde] which affects the expression of IL24 mRNA; cinnamaldehyde affects the reaction [ethylhexadecyldimethylammonium results in increased expression of IL24 mRNA]; NFE2L2 protein affects the reaction [[ethylhexadecyldimethylammonium co-treated with cinnamaldehyde] results in increased expression of IL24 mRNA] |
CTD |
PMID:37089166 |
|
NCBI chr13:44,905,362...44,910,760
|
|
G |
Il6 |
interleukin 6 |
multiple interactions |
ISO EXP |
cinnamaldehyde inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL6 protein] [ethylhexadecyldimethylammonium co-treated with cinnamaldehyde] results in increased expression of IL6 mRNA; [NFE2L2 protein affects the susceptibility to cinnamaldehyde] which affects the expression of IL6 mRNA; cinnamaldehyde affects the reaction [ethylhexadecyldimethylammonium results in increased expression of IL6 mRNA]; NFE2L2 protein affects the reaction [[ethylhexadecyldimethylammonium co-treated with cinnamaldehyde] results in increased expression of IL6 mRNA] cinnamaldehyde inhibits the reaction [Testosterone results in increased expression of IL6 protein]; cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein] |
CTD |
PMID:17868967 PMID:32628957 PMID:33522063 PMID:37089166 |
|
NCBI chr 4:5,889,999...5,894,575
|
|
G |
Il7r |
interleukin 7 receptor |
increases expression |
ISO |
cinnamaldehyde results in increased expression of IL7R mRNA |
CTD |
PMID:20713136 |
|
NCBI chr 2:58,452,393...58,477,757
|
|
G |
Insig1 |
insulin induced gene 1 |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of INSIG1 mRNA |
CTD |
PMID:17178418 |
|
NCBI chr 4:8,049,339...8,057,812
|
|
G |
Irf3 |
interferon regulatory factor 3 |
multiple interactions |
ISO |
cinnamaldehyde inhibits the reaction [Lipopolysaccharides results in increased activity of IRF3 protein] |
CTD |
PMID:17920563 |
|
NCBI chr 1:104,616,608...104,621,402
|
|
G |
Itga11 |
integrin subunit alpha 11 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of ITGA11 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 8:63,145,998...63,254,714
|
|
G |
Jak1 |
Janus kinase 1 |
multiple interactions |
EXP |
cinnamaldehyde inhibits the reaction [Testosterone results in increased expression of JAK1 protein] |
CTD |
PMID:32628957 |
|
NCBI chr 5:120,895,606...121,004,207
|
|
G |
Jak2 |
Janus kinase 2 |
multiple interactions |
EXP |
cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of JAK2 protein] |
CTD |
PMID:33522063 |
|
NCBI chr 1:236,408,905...236,468,769
|
|
G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
decreases expression |
ISO |
cinnamaldehyde analog results in decreased expression of JUN protein |
CTD |
PMID:17510524 |
|
NCBI chr 5:115,009,900...115,012,993
|
|
G |
Jund |
JunD proto-oncogene, AP-1 transcription factor subunit |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of JUND mRNA |
CTD |
PMID:17178418 |
|
NCBI chr16:18,734,121...18,735,799
|
|
G |
Keap1 |
Kelch-like ECH-associated protein 1 |
affects expression increases expression |
ISO |
cinnamaldehyde affects the expression of KEAP1 mRNA cinnamaldehyde results in increased expression of KEAP1 protein |
CTD |
PMID:19033392 PMID:28219650 |
|
NCBI chr 8:19,768,375...19,777,862
|
|
G |
Lhfpl6 |
LHFPL tetraspan subfamily member 6 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of LHFPL6 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 2:139,276,810...139,474,740
|
|
G |
Lmcd1 |
LIM and cysteine-rich domains 1 |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of LMCD1 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 4:145,393,153...145,452,049
|
|
G |
Lmna |
lamin A/C |
increases metabolic processing |
ISO |
cinnamaldehyde results in increased metabolism of LMNA protein |
CTD |
PMID:29267982 |
|
NCBI chr 2:176,237,564...176,265,301
|
|
G |
Lpl |
lipoprotein lipase |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of LPL mRNA |
CTD |
PMID:21401097 |
|
NCBI chr16:25,596,205...25,621,928
|
|
G |
Lrp12 |
LDL receptor related protein 12 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of LRP12 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 7:70,941,068...71,012,409
|
|
G |
Lta |
lymphotoxin alpha |
increases expression |
ISO |
cinnamaldehyde results in increased expression of LTA mRNA |
CTD |
PMID:19000754 |
|
NCBI chr20:3,622,291...3,625,852
|
|
G |
Magix |
MAGI family member, X-linked |
increases expression |
ISO |
cinnamaldehyde results in increased expression of MAGIX mRNA |
CTD |
PMID:19524605 |
|
NCBI chr X:14,824,114...14,832,466
|
|
G |
Map2k2 |
mitogen activated protein kinase kinase 2 |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of MAP2K2 mRNA |
CTD |
PMID:17178418 |
|
NCBI chr 7:9,241,449...9,264,216
|
|
G |
Map3k14 |
mitogen-activated protein kinase kinase kinase 14 |
decreases phosphorylation |
EXP |
cinnamaldehyde results in decreased phosphorylation of MAP3K14 protein |
CTD |
PMID:17486422 |
|
NCBI chr10:88,665,417...88,715,669
|
|
G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions decreases phosphorylation |
EXP ISO |
cinnamaldehyde inhibits the reaction [Glucose results in increased phosphorylation of MAPK1 protein] cinnamaldehyde results in increased phosphorylation of and results in increased activity of MAPK1 protein cinnamaldehyde results in decreased phosphorylation of MAPK1 protein cinnamaldehyde inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:15964311 PMID:17486422 PMID:17868967 PMID:20060012 |
|
NCBI chr11:97,462,025...97,529,193
|
|
G |
Mapk14 |
mitogen activated protein kinase 14 |
multiple interactions decreases phosphorylation |
ISO EXP |
cinnamaldehyde results in increased phosphorylation of and results in increased activity of MAPK14 protein; pyrazolanthrone inhibits the reaction [cinnamaldehyde results in increased phosphorylation of MAPK14 protein]; SB 203580 inhibits the reaction [cinnamaldehyde results in increased phosphorylation of MAPK14 protein] cinnamaldehyde results in decreased phosphorylation of MAPK14 protein |
CTD |
PMID:15964311 PMID:17486422 |
|
NCBI chr20:6,751,288...6,812,294
|
|
G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions decreases phosphorylation |
EXP ISO |
cinnamaldehyde inhibits the reaction [Glucose results in increased phosphorylation of MAPK3 protein] cinnamaldehyde inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK3 protein] cinnamaldehyde results in increased phosphorylation of and results in increased activity of MAPK3 protein cinnamaldehyde results in decreased phosphorylation of MAPK3 protein |
CTD |
PMID:15964311 PMID:17486422 PMID:17868967 PMID:20060012 |
|
NCBI chr 1:190,797,189...190,803,411
|
|
G |
Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions increases phosphorylation |
ISO |
cinnamaldehyde results in increased phosphorylation of and results in increased activity of MAPK8 protein; pyrazolanthrone inhibits the reaction [cinnamaldehyde results in increased phosphorylation of MAPK8 protein]; SB 203580 inhibits the reaction [cinnamaldehyde results in increased phosphorylation of MAPK8 protein] cinnamaldehyde inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein] |
CTD |
PMID:15964311 PMID:17868967 PMID:21469739 |
|
NCBI chr16:8,645,171...8,728,225
|
|
G |
Mapk9 |
mitogen-activated protein kinase 9 |
multiple interactions |
ISO |
cinnamaldehyde inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK9 protein] |
CTD |
PMID:17868967 |
|
NCBI chr10:34,670,750...34,711,972
|
|
G |
Mapkapk5 |
MAPK activated protein kinase 5 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of MAPKAPK5 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr12:40,654,220...40,673,740
|
|
G |
Mark4 |
microtubule affinity regulating kinase 4 |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of MARK4 mRNA |
CTD |
PMID:17178418 |
|
NCBI chr 1:88,203,352...88,239,858
|
|
G |
Mcl1 |
MCL1 apoptosis regulator, BCL2 family member |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of MCL1 protein |
CTD |
PMID:15964311 |
|
NCBI chr 2:185,884,840...185,912,532
|
|
G |
Mdm2 |
MDM2 proto-oncogene |
increases expression |
ISO |
cinnamaldehyde results in increased expression of MDM2 mRNA |
CTD |
PMID:19000754 |
|
NCBI chr 7:55,176,558...55,201,757
|
|
G |
Mif |
macrophage migration inhibitory factor |
increases expression |
ISO |
cinnamaldehyde results in increased expression of MIF mRNA |
CTD |
PMID:11244134 |
|
NCBI chr20:12,790,919...12,791,784
|
|
G |
Mmp2 |
matrix metallopeptidase 2 |
multiple interactions |
ISO |
cinnamaldehyde inhibits the reaction [TGFB1 protein results in increased expression of MMP2 protein] |
CTD |
PMID:28258635 |
|
NCBI chr19:30,327,643...30,355,856
|
|
G |
Mmp3 |
matrix metallopeptidase 3 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of MMP3 mRNA |
CTD |
PMID:30806763 |
|
NCBI chr 8:12,925,267...12,938,828
|
|
G |
Mpo |
myeloperoxidase |
increases activity multiple interactions |
ISO EXP |
cinnamaldehyde results in increased activity of MPO protein cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [cinnamaldehyde results in increased activity of MPO protein]; Camphor inhibits the reaction [cinnamaldehyde results in increased activity of MPO protein]; Ruthenium Red inhibits the reaction [cinnamaldehyde results in increased activity of MPO protein] |
CTD |
PMID:21466812 PMID:33522063 |
|
NCBI chr10:73,092,124...73,102,057
|
|
G |
Mx1 |
MX dynamin like GTPase 1 |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of MX1 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr11:36,799,659...36,825,209
|
|
G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
increases expression decreases expression |
ISO |
cinnamaldehyde results in increased expression of MYC mRNA cinnamaldehyde results in decreased expression of MYC protein |
CTD |
PMID:21729535 PMID:24211530 |
|
NCBI chr 7:95,483,105...95,488,031
|
|
G |
Myd88 |
MYD88, innate immune signal transduction adaptor |
multiple interactions |
ISO |
cinnamaldehyde inhibits the reaction [Lipopolysaccharides results in increased expression of MYD88 mRNA]; cinnamaldehyde inhibits the reaction [Poly I-C results in increased expression of MYD88 mRNA] |
CTD |
PMID:18306459 |
|
NCBI chr 8:127,952,161...127,956,230
|
|
G |
Ncf1 |
neutrophil cytosolic factor 1 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of NCF1 mRNA |
CTD |
PMID:19000754 |
|
NCBI chr12:28,121,816...28,131,080
|
|
G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
increases expression affects response to substance increases activity multiple interactions affects localization affects expression |
ISO |
cinnamaldehyde analog results in increased expression of NFE2L2 protein; cinnamaldehyde results in increased expression of NFE2L2 protein NFE2L2 protein affects the susceptibility to cinnamaldehyde cinnamaldehyde results in increased activity of NFE2L2 protein cinnamaldehyde inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of NFE2L2 protein]; NFE2L2 protein inhibits the reaction [cinnamaldehyde results in decreased abundance of Glutathione]; NFE2L2 protein inhibits the reaction [cinnamaldehyde results in increased abundance of Reactive Oxygen Species]; NFE2L2 protein inhibits the reaction [cinnamaldehyde results in increased expression of CCL3 mRNA]; NFE2L2 protein inhibits the reaction [cinnamaldehyde results in increased expression of CXCL1 mRNA]; NFE2L2 protein inhibits the reaction [cinnamaldehyde results in increased expression of CXCL10 mRNA]; NFE2L2 protein inhibits the reaction [cinnamaldehyde results in increased expression of IL12A mRNA]; NFE2L2 protein inhibits the reaction [cinnamaldehyde results in increased expression of IL1B mRNA]; NFE2L2 protein promotes the reaction [cinnamaldehyde results in increased expression of CAT mRNA]; NFE2L2 protein promotes the reaction [cinnamaldehyde results in increased expression of GPX1 mRNA]; NFE2L2 protein promotes the reaction [cinnamaldehyde results in increased expression of GPX2 mRNA]; NFE2L2 protein promotes the reaction [cinnamaldehyde results in increased expression of GPX5 mRNA]; NFE2L2 protein promotes the reaction [cinnamaldehyde results in increased expression of GPX6 mRNA]; NFE2L2 protein promotes the reaction [cinnamaldehyde results in increased expression of GSR mRNA]; NFE2L2 protein promotes the reaction [cinnamaldehyde results in increased expression of NOS2 mRNA] NFE2L2 affects the susceptibility to cinnamaldehyde cinnamaldehyde affects the localization of NFE2L2 protein [cinnamaldehyde results in increased activity of NFE2L2 protein] inhibits the reaction [TNF protein affects the localization of RELA protein]; [cinnamaldehyde results in increased activity of NFE2L2 protein] inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; [cinnamaldehyde results in increased activity of NFE2L2 protein] which results in increased expression of GCLC mRNA; [cinnamaldehyde results in increased activity of NFE2L2 protein] which results in increased expression of GCLM mRNA; [cinnamaldehyde results in increased activity of NFE2L2 protein] which results in increased glutathionylation of RELA protein; [ethylhexadecyldimethylammonium co-treated with cinnamaldehyde] results in increased expression of NFE2L2 protein; [NFE2L2 protein affects the susceptibility to cinnamaldehyde] which affects the expression of CXCL8 mRNA; [NFE2L2 protein affects the susceptibility to cinnamaldehyde] which affects the expression of IL1A mRNA; [NFE2L2 protein affects the susceptibility to cinnamaldehyde] which affects the expression of IL1B mRNA; [NFE2L2 protein affects the susceptibility to cinnamaldehyde] which affects the expression of IL23A mRNA; [NFE2L2 protein affects the susceptibility to cinnamaldehyde] which affects the expression of IL24 mRNA; [NFE2L2 protein affects the susceptibility to cinnamaldehyde] which affects the expression of IL6 mRNA; cinnamaldehyde results in increased expression of and results in increased activity of NFE2L2 protein; NFE2L2 mRNA affects the reaction [cinnamaldehyde results in increased expression of GCLC protein]; NFE2L2 mRNA promotes the reaction [cinnamaldehyde results in increased expression of AKR1C2 mRNA]; NFE2L2 mRNA promotes the reaction [cinnamaldehyde results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [[ethylhexadecyldimethylammonium co-treated with cinnamaldehyde] results in increased expression of CXCL8 mRNA]; NFE2L2 protein affects the reaction [[ethylhexadecyldimethylammonium co-treated with cinnamaldehyde] results in increased expression of IL1A mRNA]; NFE2L2 protein affects the reaction [[ethylhexadecyldimethylammonium co-treated with cinnamaldehyde] results in increased expression of IL1B mRNA]; NFE2L2 protein affects the reaction [[ethylhexadecyldimethylammonium co-treated with cinnamaldehyde] results in increased expression of IL23A mRNA]; NFE2L2 protein affects the reaction [[ethylhexadecyldimethylammonium co-treated with cinnamaldehyde] results in increased expression of IL24 mRNA]; NFE2L2 protein affects the reaction [[ethylhexadecyldimethylammonium co-treated with cinnamaldehyde] results in increased expression of IL6 mRNA] cinnamaldehyde affects the expression of NFE2L2 protein |
CTD |
PMID:18304597 PMID:18482591 PMID:19033392 PMID:20351055 PMID:21469739 PMID:23564646 PMID:26244607 PMID:28219650 PMID:30806763 PMID:31187328 PMID:37089166 More...
|
|
NCBI chr 3:81,001,529...81,031,165
|
|
G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
decreases expression |
ISO EXP |
cinnamaldehyde results in decreased expression of NFKB1 mRNA cinnamaldehyde results in decreased expression of NFKB1 protein |
CTD |
PMID:17486422 PMID:20385217 PMID:28219650 |
|
NCBI chr 2:226,689,745...226,805,897
|
|
G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions |
ISO |
cinnamaldehyde inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein] |
CTD |
PMID:20467561 |
|
NCBI chr 6:78,593,844...78,597,307
|
|
G |
Ninl |
ninein-like |
increases expression |
ISO |
cinnamaldehyde results in increased expression of NINL mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 3:139,748,353...139,814,683
|
|
G |
Nos2 |
nitric oxide synthase 2 |
affects expression multiple interactions decreases expression |
ISO EXP |
cinnamaldehyde affects the expression of NOS2 mRNA cinnamaldehyde inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; NFE2L2 protein promotes the reaction [cinnamaldehyde results in increased expression of NOS2 mRNA] cinnamaldehyde results in decreased expression of NOS2 protein |
CTD |
PMID:17486422 PMID:20467561 PMID:28219650 |
|
NCBI chr10:64,313,335...64,349,221
|
|
G |
Notch3 |
notch receptor 3 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of NOTCH3 mRNA |
CTD |
PMID:20713136 |
|
NCBI chr 7:11,132,984...11,184,025
|
|
G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
increases expression multiple interactions increases activity |
ISO |
cinnamaldehyde analog results in increased expression of NQO1 mRNA; cinnamaldehyde results in increased expression of NQO1 mRNA [ethylhexadecyldimethylammonium co-treated with cinnamaldehyde] results in increased expression of NQO1 mRNA cinnamaldehyde results in increased activity of NQO1 protein |
CTD |
PMID:18482591 PMID:19033392 PMID:19524605 PMID:24211530 PMID:28219650 PMID:30806763 PMID:37089166 More...
|
|
NCBI chr19:52,205,374...52,220,267
|
|
G |
Nrf1 |
nuclear respiratory factor 1 |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of NRF1 mRNA |
CTD |
PMID:28219650 |
|
NCBI chr 4:58,664,932...58,772,328
|
|
G |
Panx2 |
pannexin 2 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of PANX2 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 7:120,139,259...120,153,056
|
|
G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
increases cleavage |
ISO |
cinnamaldehyde analog results in increased cleavage of PARP1 protein |
CTD |
PMID:16343908 |
|
NCBI chr13:94,839,484...94,871,295
|
|
G |
Pck1 |
phosphoenolpyruvate carboxykinase 1 |
multiple interactions |
EXP |
cinnamaldehyde inhibits the reaction [Streptozocin results in increased expression of PCK1 mRNA] |
CTD |
PMID:20363216 |
|
NCBI chr 3:182,348,572...182,354,521
|
|
G |
Pde3b |
phosphodiesterase 3B |
increases expression |
ISO |
cinnamaldehyde results in increased expression of PDE3B mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 1:168,606,762...168,770,078
|
|
G |
Pdk1 |
pyruvate dehydrogenase kinase 1 |
multiple interactions |
ISO |
cinnamaldehyde inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of PDK1 protein] |
CTD |
PMID:20467561 |
|
NCBI chr 3:77,113,464...77,144,145
|
|
G |
Phlda2 |
pleckstrin homology-like domain, family A, member 2 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of PHLDA2 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 1:198,696,897...198,699,292
|
|
G |
Pir |
pirin |
increases expression |
ISO |
cinnamaldehyde results in increased expression of PIR mRNA |
CTD |
PMID:19524605 |
|
NCBI chr X:33,740,428...33,851,049
|
|
G |
Pklr |
pyruvate kinase L/R |
multiple interactions |
EXP |
cinnamaldehyde inhibits the reaction [Streptozocin results in decreased expression of PKLR mRNA] |
CTD |
PMID:20363216 |
|
NCBI chr 2:176,840,779...176,849,637
|
|
G |
Pkm |
pyruvate kinase M1/2 |
increases metabolic processing |
ISO |
cinnamaldehyde results in increased metabolism of PKM protein |
CTD |
PMID:29267982 |
|
NCBI chr 8:68,949,731...68,975,394
|
|
G |
Plau |
plasminogen activator, urokinase |
multiple interactions |
ISO |
cinnamaldehyde inhibits the reaction [TGFB1 protein results in increased expression of PLAU protein] |
CTD |
PMID:28258635 |
|
NCBI chr15:3,505,485...3,511,987
|
|
G |
Pmaip1 |
phorbol-12-myristate-13-acetate-induced protein 1 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of PMAIP1 mRNA |
CTD |
PMID:20713136 |
|
NCBI chr18:62,255,970...62,262,384
|
|
G |
Por |
cytochrome p450 oxidoreductase |
increases expression |
ISO |
cinnamaldehyde results in increased expression of POR mRNA |
CTD |
PMID:19000754 |
|
NCBI chr12:26,587,674...26,655,612
|
|
G |
Pparg |
peroxisome proliferator-activated receptor gamma |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of PPARG mRNA |
CTD |
PMID:21401097 |
|
NCBI chr 4:150,095,743...150,221,104
|
|
G |
Ppbp |
pro-platelet basic protein |
multiple interactions increases expression |
ISO |
cinnamaldehyde results in increased expression of and results in increased secretion of PPBP protein cinnamaldehyde results in increased expression of PPBP mRNA |
CTD |
PMID:23624239 |
|
NCBI chr14:17,586,495...17,587,299
|
|
G |
Ppfibp1 |
PPFIA binding protein 1 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of PPFIBP1 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 4:179,807,579...179,951,428
|
|
G |
Ppp1r10 |
protein phosphatase 1, regulatory subunit 10 |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of PPP1R10 mRNA |
CTD |
PMID:17178418 |
|
NCBI chr20:2,827,802...2,842,418
|
|
G |
Prdm5 |
PR/SET domain 5 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of PRDM5 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 4:95,075,736...95,237,921
|
|
G |
Ptgr1 |
prostaglandin reductase 1 |
multiple interactions |
EXP |
[PTGR1 protein co-treated with NADP] affects the reduction of cinnamaldehyde |
CTD |
PMID:11524419 |
|
NCBI chr 5:78,579,060...78,597,671
|
|
G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions decreases expression increases expression |
ISO EXP |
cinnamaldehyde inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 mRNA]; cinnamaldehyde inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 protein] cinnamaldehyde inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] cinnamaldehyde inhibits the reaction [IL1B protein results in increased activity of PTGS2 protein] cinnamaldehyde results in decreased expression of PTGS2 protein cinnamaldehyde results in increased expression of PTGS2 mRNA |
CTD |
PMID:16624280 PMID:17486422 PMID:17920563 PMID:21807015 PMID:30806763 |
|
NCBI chr13:64,714,063...64,722,320
|
|
G |
Rac1 |
Rac family small GTPase 1 |
decreases expression |
EXP |
cinnamaldehyde results in decreased expression of RAC1 protein |
CTD |
PMID:17486422 |
|
NCBI chr12:16,150,411...16,170,864
|
|
G |
Rbp4 |
retinol binding protein 4 |
multiple interactions |
EXP |
cinnamaldehyde inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased secretion of RBP4 protein] |
CTD |
PMID:19080170 |
|
NCBI chr 1:235,893,917...235,901,315
|
|
G |
Rela |
RELA proto-oncogene, NF-kB subunit |
decreases expression multiple interactions increases glutathionylation |
EXP ISO |
cinnamaldehyde results in decreased expression of RELA protein cinnamaldehyde inhibits the reaction [Testosterone results in increased expression of RELA protein] cinnamaldehyde results in increased glutathionylation of RELA protein [Buthionine Sulfoximine results in decreased abundance of Glutathione] inhibits the reaction [cinnamaldehyde results in increased glutathionylation of RELA protein]; [Cadmium Chloride affects the activity of GLRX protein] inhibits the reaction [cinnamaldehyde results in increased glutathionylation of RELA protein]; [cinnamaldehyde results in increased abundance of Glutathione] which results in increased glutathionylation of RELA protein; [cinnamaldehyde results in increased abundance of Hydrogen Peroxide] which results in increased glutathionylation of RELA protein; [cinnamaldehyde results in increased activity of GLRX protein] inhibits the reaction [TNF protein affects the localization of RELA protein]; [cinnamaldehyde results in increased activity of GLRX protein] which results in increased glutathionylation of RELA protein; [cinnamaldehyde results in increased activity of NFE2L2 protein] inhibits the reaction [TNF protein affects the localization of RELA protein]; [cinnamaldehyde results in increased activity of NFE2L2 protein] which results in increased glutathionylation of RELA protein; Buthionine Sulfoximine inhibits the reaction [cinnamaldehyde inhibits the reaction [TNF protein affects the localization of RELA protein]]; cinnamaldehyde inhibits the reaction [TNF protein affects the localization of RELA protein]; Dithiothreitol inhibits the reaction [cinnamaldehyde results in increased glutathionylation of RELA protein] |
CTD |
PMID:17486422 PMID:20351055 PMID:32628957 |
|
NCBI chr 1:212,354,336...212,364,815
|
|
G |
Rtn4rl1 |
reticulon 4 receptor-like 1 |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of RTN4RL1 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr10:60,541,584...60,615,302
|
|
G |
Scd |
stearoyl-CoA desaturase |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of SCD1 mRNA |
CTD |
PMID:21401097 |
|
NCBI chr 1:253,218,968...253,232,101
|
|
G |
Sel1l3 |
SEL1L family member 3 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of SEL1L3 mRNA |
CTD |
PMID:24211530 |
|
NCBI chr14:57,775,515...57,882,076
|
|
G |
Serpinb3 |
serpin family B member 3 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of SERPINB3 mRNA |
CTD |
PMID:30806763 |
|
NCBI chr13:23,274,120...23,280,660
|
|
G |
Serpine1 |
serpin family E member 1 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of SERPINE1 mRNA |
CTD |
PMID:19000754 |
|
NCBI chr12:25,237,977...25,248,356
|
|
G |
Sgcd |
sarcoglycan, delta |
increases expression |
ISO |
cinnamaldehyde results in increased expression of SGCD mRNA |
CTD |
PMID:19524605 |
|
NCBI chr10:31,346,480...32,328,364
|
|
G |
Slc14a1 |
solute carrier family 14 member 1 (Kidd blood group) |
increases expression |
ISO |
cinnamaldehyde results in increased expression of SLC14A1 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr18:71,565,453...71,608,807
|
|
G |
Slc1a2 |
solute carrier family 1 member 2 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of SLC1A2 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 3:109,460,109...109,590,445
|
|
G |
Slc26a7 |
solute carrier family 26 member 7 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of SLC26A7 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 5:27,884,400...28,021,865
|
|
G |
Slc2a1 |
solute carrier family 2 member 1 |
increases activity multiple interactions |
ISO |
cinnamaldehyde results in increased activity of SLC2A1 protein [cinnamaldehyde co-treated with Glucose deficiency] results in decreased activity of SLC2A1 protein; Cysteine inhibits the reaction [[cinnamaldehyde co-treated with Glucose deficiency] results in decreased activity of SLC2A1 protein]; Mercaptoethanol inhibits the reaction [[cinnamaldehyde co-treated with Glucose deficiency] results in decreased activity of SLC2A1 protein] |
CTD |
PMID:20955755 |
|
NCBI chr 5:138,002,522...138,030,742
|
|
G |
Slc2a13 |
solute carrier family 2 member 13 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of SLC2A13 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 7:122,399,329...122,726,605
|
|
G |
Slc2a4 |
solute carrier family 2 member 4 |
multiple interactions |
EXP |
cinnamaldehyde inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein]; cinnamaldehyde inhibits the reaction [Streptozocin affects the localization of SLC2A4 protein] |
CTD |
PMID:19080170 PMID:20363216 |
|
NCBI chr10:55,164,721...55,170,289
|
|
G |
Slc35d2 |
solute carrier family 35 member D2 |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of SLC35D2 mRNA |
CTD |
PMID:17178418 |
|
NCBI chr17:987,899...1,019,747
|
|
G |
Slc7a11 |
solute carrier family 7 member 11 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of SLC7A11 mRNA |
CTD |
PMID:17178418 PMID:24211530 PMID:30806763 |
|
NCBI chr 2:136,532,912...136,668,560
|
|
G |
Slc8a1 |
solute carrier family 8 member A1 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of SLC8A1 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 6:13,194,609...13,547,369
|
|
G |
Smad2 |
SMAD family member 2 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of SMAD2 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr18:72,124,792...72,193,345
|
|
G |
Snca |
synuclein alpha |
multiple interactions |
ISO |
cinnamaldehyde inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of SNCA protein] |
CTD |
PMID:31187328 |
|
NCBI chr 4:91,026,474...91,127,444
|
|
G |
Snx24 |
sorting nexin 24 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of SNX24 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr18:46,670,987...46,826,070
|
|
G |
Socs3 |
suppressor of cytokine signaling 3 |
multiple interactions |
EXP |
cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SOCS3 protein] |
CTD |
PMID:33522063 |
|
NCBI chr10:103,692,579...103,695,975
|
|
G |
Sod2 |
superoxide dismutase 2 |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of SOD2 mRNA |
CTD |
PMID:28219650 |
|
NCBI chr 1:50,043,323...50,050,168
|
|
G |
Sqstm1 |
sequestosome 1 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of SQSTM1 mRNA |
CTD |
PMID:24211530 |
|
NCBI chr10:35,026,598...35,037,750
|
|
G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
multiple interactions decreases expression |
ISO |
dorsomorphin inhibits the reaction [cinnamaldehyde results in decreased expression of SREBF1 mRNA] |
CTD |
PMID:21401097 |
|
NCBI chr10:45,507,152...45,529,164
|
|
G |
Srsf11 |
serine and arginine rich splicing factor 11 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of SRSF11 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 2:247,074,623...247,101,460
|
|
G |
Srxn1 |
sulfiredoxin 1 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of SRXN1 mRNA |
CTD |
PMID:19000754 |
|
NCBI chr 3:161,064,812...161,070,372
|
|
G |
Stat3 |
signal transducer and activator of transcription 3 |
multiple interactions |
EXP |
cinnamaldehyde inhibits the reaction [Testosterone results in increased expression of STAT3 protein modified form]; cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein] |
CTD |
PMID:32628957 PMID:33522063 |
|
NCBI chr10:86,311,528...86,363,513
|
|
G |
Stau2 |
staufen double-stranded RNA binding protein 2 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of STAU2 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 5:2,840,741...3,084,935
|
|
G |
Stk24 |
serine/threonine kinase 24 |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of STK24 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr15:104,770,556...104,866,524
|
|
G |
Sufu |
SUFU negative regulator of hedgehog signaling |
increases expression |
ISO |
cinnamaldehyde results in increased expression of SUFU mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 1:255,199,108...255,296,983
|
|
G |
Syne2 |
spectrin repeat containing nuclear envelope protein 2 |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of SYNE2 mRNA |
CTD |
PMID:24211530 |
|
NCBI chr 6:100,272,729...100,586,364
|
|
G |
Tbxa2r |
thromboxane A2 receptor |
multiple interactions |
ISO |
cinnamaldehyde binds to and results in decreased activity of TBXA2R protein |
CTD |
PMID:17079160 |
|
NCBI chr 7:9,034,077...9,041,489
|
|
G |
Tgfb1 |
transforming growth factor, beta 1 |
increases expression multiple interactions |
ISO |
cinnamaldehyde results in increased expression of TGFB1 mRNA cinnamaldehyde inhibits the reaction [TGFB1 protein results in increased expression of MMP2 protein]; cinnamaldehyde inhibits the reaction [TGFB1 protein results in increased expression of PLAU protein] |
CTD |
PMID:11244134 PMID:28258635 |
|
NCBI chr 1:90,324,312...90,340,627
|
|
G |
Tgfb1i1 |
transforming growth factor beta 1 induced transcript 1 |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of TGFB1I1 mRNA |
CTD |
PMID:17178418 |
|
NCBI chr 1:182,828,553...182,835,465
|
|
G |
Th |
tyrosine hydroxylase |
multiple interactions |
ISO |
cinnamaldehyde inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH protein] |
CTD |
PMID:31187328 |
|
NCBI chr 1:207,500,959...207,508,276
|
|
G |
Thnsl2 |
threonine synthase-like 2 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of THNSL2 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 4:103,112,974...103,132,122
|
|
G |
Tlr3 |
toll-like receptor 3 |
multiple interactions |
ISO |
cinnamaldehyde inhibits the reaction [Poly I-C results in increased expression of TLR3 mRNA] |
CTD |
PMID:18306459 |
|
NCBI chr16:53,554,916...53,572,321
|
|
G |
Tlr4 |
toll-like receptor 4 |
increases expression multiple interactions |
ISO |
cinnamaldehyde results in increased expression of TLR4 mRNA cinnamaldehyde inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to TLR4 protein]]; cinnamaldehyde inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA] |
CTD |
PMID:17920563 PMID:18306459 PMID:19524605 |
|
NCBI chr 5:85,161,247...85,174,882
|
|
G |
Tnf |
tumor necrosis factor |
multiple interactions increases expression |
ISO EXP |
[cinnamaldehyde results in increased activity of GLRX protein] inhibits the reaction [TNF protein affects the localization of RELA protein]; [cinnamaldehyde results in increased activity of GLRX protein] inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; [cinnamaldehyde results in increased activity of NFE2L2 protein] inhibits the reaction [TNF protein affects the localization of RELA protein]; [cinnamaldehyde results in increased activity of NFE2L2 protein] inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; Buthionine Sulfoximine inhibits the reaction [cinnamaldehyde inhibits the reaction [TNF protein affects the localization of RELA protein]]; Buthionine Sulfoximine inhibits the reaction [cinnamaldehyde inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]; cinnamaldehyde inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; cinnamaldehyde inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]; cinnamaldehyde inhibits the reaction [TNF protein affects the localization of RELA protein]; cinnamaldehyde inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] cinnamaldehyde inhibits the reaction [Testosterone results in increased expression of TNF protein]; cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein] cinnamaldehyde inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]; cinnamaldehyde inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; cinnamaldehyde inhibits the reaction [lipoteichoic acid results in increased secretion of TNF protein] cinnamaldehyde results in increased expression of TNF mRNA |
CTD |
PMID:17868967 PMID:20351055 PMID:20385217 PMID:20467561 PMID:21807015 PMID:32628957 PMID:33522063 More...
|
|
NCBI chr20:3,626,685...3,629,303
|
|
G |
Tnfrsf21 |
TNF receptor superfamily member 21 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of TNFRSF21 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 9:17,879,156...17,954,085
|
|
G |
Tnnt2 |
troponin T2, cardiac type |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of TNNT2 mRNA |
CTD |
PMID:24211530 |
|
NCBI chr13:49,819,123...49,837,125
|
|
G |
Tp53 |
tumor protein p53 |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of TP53 mRNA |
CTD |
PMID:17178418 |
|
NCBI chr10:54,798,871...54,810,300
|
|
G |
Traf6 |
TNF receptor associated factor 6 |
multiple interactions |
ISO |
cinnamaldehyde inhibits the reaction [Lipopolysaccharides results in increased expression of TRAF6 mRNA] |
CTD |
PMID:18306459 |
|
NCBI chr 3:87,963,517...87,988,316
|
|
G |
Trim16 |
tripartite motif-containing 16 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of TRIM16 mRNA |
CTD |
PMID:17178418 PMID:19524605 |
|
NCBI chr10:47,485,982...47,509,010
|
|
G |
Trpa1 |
transient receptor potential cation channel, subfamily A, member 1 |
increases activity affects response to substance increases response to substance multiple interactions |
EXP ISO |
cinnamaldehyde results in increased activity of TRPA1 protein TRPA1 mRNA affects the susceptibility to cinnamaldehyde TRPA1 protein results in increased susceptibility to cinnamaldehyde 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [cinnamaldehyde results in increased activity of TRPA1 protein]; 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [cinnamaldehyde results in increased activity of TRPA1 protein]; cinnamaldehyde binds to and results in increased activity of TRPA1 protein; isopentenyl pyrophosphate inhibits the reaction [cinnamaldehyde results in increased activity of TRPA1 protein]; Ruthenium Red inhibits the reaction [cinnamaldehyde results in increased activity of TRPA1 protein] TRPA1 affects the susceptibility to cinnamaldehyde 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [cinnamaldehyde results in increased activity of TRPA1 protein]; [cinnamaldehyde results in increased activity of TRPA1 protein] which results in increased transport of Calcium; edelfosine inhibits the reaction [F2RL1 protein promotes the reaction [cinnamaldehyde results in increased activity of TRPA1 protein]]; F2RL1 protein promotes the reaction [cinnamaldehyde results in increased activity of TRPA1 protein]; TRPA1 mRNA affects the reaction [cinnamaldehyde results in increased secretion of Serotonin]; TRPA1 mRNA affects the reaction [cinnamaldehyde results in increased uptake of Calcium] |
CTD |
PMID:15046718 PMID:17571167 PMID:17991581 PMID:19507004 PMID:20442136 PMID:20720158 PMID:21353389 PMID:21689654 PMID:22863862 PMID:22935519 PMID:27735854 More...
|
|
NCBI chr 5:9,163,060...9,217,325
|
|
G |
Trpv1 |
transient receptor potential cation channel, subfamily V, member 1 |
increases expression |
EXP |
cinnamaldehyde results in increased expression of TRPV1 mRNA |
CTD |
PMID:20390747 |
|
NCBI chr10:58,349,936...58,375,021
|
|
G |
Ttn |
titin |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of TTN mRNA |
CTD |
PMID:19000754 |
|
NCBI chr 3:82,059,648...82,332,130
|
|
G |
Txnrd1 |
thioredoxin reductase 1 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of TXNRD1 mRNA; cinnamaldehyde results in increased expression of TXNRD1 protein |
CTD |
PMID:18304597 PMID:19000754 PMID:24211530 PMID:30806763 |
|
NCBI chr 7:22,717,620...22,802,553
|
|
G |
Txnrd2 |
thioredoxin reductase 2 |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of TXNRD2 mRNA |
CTD |
PMID:28219650 |
|
NCBI chr11:82,519,996...82,568,156
|
|
G |
Ube2d1 |
ubiquitin-conjugating enzyme E2D 1 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of UBE2D1 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr20:17,308,459...17,341,427
|
|
G |
Ugp2 |
UDP-glucose pyrophosphorylase 2 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of UGP2 mRNA |
CTD |
PMID:17178418 |
|
NCBI chr14:95,456,330...95,497,483
|
|
G |
Ung |
uracil-DNA glycosylase |
decreases expression |
ISO |
cinnamaldehyde results in decreased expression of UNG mRNA |
CTD |
PMID:19000754 |
|
NCBI chr12:48,145,838...48,154,789
|
|
G |
Xbp1 |
X-box binding protein 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [cinnamaldehyde inhibits the reaction [Tunicamycin results in increased splicing of XBP1 mRNA]]; cinnamaldehyde inhibits the reaction [Tunicamycin results in increased splicing of XBP1 mRNA] |
CTD |
PMID:35840659 |
|
NCBI chr14:84,604,623...84,609,707
|
|
G |
Xdh |
xanthine dehydrogenase |
multiple interactions |
EXP |
cinnamaldehyde inhibits the reaction [Testosterone results in increased activity of XDH protein modified form] |
CTD |
PMID:32628957 |
|
NCBI chr 6:21,530,463...21,592,172
|
|
G |
Xiap |
X-linked inhibitor of apoptosis |
multiple interactions decreases expression |
ISO |
Vitamin E inhibits the reaction [cinnamaldehyde results in decreased expression of XIAP protein] |
CTD |
PMID:15566391 |
|
NCBI chr X:125,756,107...125,803,979
|
|
G |
Zdhhc21 |
zinc finger DHHC-type palmitoyltransferase 21 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of ZDHHC21 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 5:97,227,621...97,286,866
|
|
G |
Zfp639 |
zinc finger protein 639 |
increases expression |
ISO |
cinnamaldehyde results in increased expression of ZNF639 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr 2:115,292,431...115,305,798
|
|
|
G |
Aldh1a1 |
aldehyde dehydrogenase 1 family, member A1 |
multiple interactions |
ISO |
[4-dimethylaminocinnamaldehyde co-treated with Adenosine Monophosphate] binds to ALDH1A1 protein |
CTD |
PMID:10609638 |
|
NCBI chr 1:218,000,470...218,152,962
|
|
G |
Aldh2 |
aldehyde dehydrogenase 2 family member |
affects binding multiple interactions |
ISO |
4-dimethylaminocinnamaldehyde binds to ALDH2 protein acetophenone inhibits the reaction [4-dimethylaminocinnamaldehyde binds to ALDH2 protein]; benzaldehyde inhibits the reaction [4-dimethylaminocinnamaldehyde binds to ALDH2 protein]; phenacyl bromide inhibits the reaction [4-dimethylaminocinnamaldehyde binds to ALDH2 protein] |
CTD |
PMID:10609638 |
|
NCBI chr12:40,610,244...40,643,220
|
|
|
G |
Aicda |
activation-induced cytidine deaminase |
affects expression |
ISO |
hexyl cinnamic aldehyde affects the expression of AICDA mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 4:157,446,120...157,455,958
|
|
G |
Akr1b1 |
aldo-keto reductase family 1 member B1 |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of AKR1B1 mRNA |
CTD |
PMID:20566472 |
|
NCBI chr 4:63,899,222...63,913,315
|
|
G |
Akr1b10 |
aldo-keto reductase family 1 member B10 |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of AKR1B10 mRNA |
CTD |
PMID:20566472 |
|
NCBI chr 4:64,005,632...64,027,860
|
|
G |
Akr1c1 |
aldo-keto reductase family 1, member C1 |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of AKR1C1 mRNA |
CTD |
PMID:20566472 |
|
NCBI chr17:70,720,397...70,747,285
|
|
G |
Akr1c3 |
aldo-keto reductase family 1, member C3 |
increases expression affects expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of AKR1C3 mRNA hexyl cinnamic aldehyde affects the expression of AKR1C18 mRNA |
CTD |
PMID:20566472 PMID:22302311 |
|
NCBI chr17:71,020,884...71,037,779
|
|
G |
Atf3 |
activating transcription factor 3 |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of ATF3 mRNA |
CTD |
PMID:27965148 |
|
NCBI chr13:105,274,103...105,331,653
|
|
G |
Cat |
catalase |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of CAT mRNA |
CTD |
PMID:20566472 |
|
NCBI chr 3:110,297,340...110,329,526
|
|
G |
Ccl2 |
C-C motif chemokine ligand 2 |
increases secretion |
ISO |
hexyl cinnamic aldehyde results in increased secretion of CCL2 protein |
CTD |
PMID:22245253 |
|
NCBI chr10:67,503,077...67,504,875
|
|
G |
Ccl4 |
C-C motif chemokine ligand 4 |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of CCL4 protein |
CTD |
PMID:18353026 |
|
NCBI chr10:68,963,893...68,965,728
|
|
G |
Ccna2 |
cyclin A2 |
affects expression |
ISO |
hexyl cinnamic aldehyde affects the expression of CCNA2 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 2:121,355,363...121,361,762
|
|
G |
Ccnb1 |
cyclin B1 |
affects expression |
ISO |
hexyl cinnamic aldehyde affects the expression of CCNB1 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 2:33,646,252...33,655,225
|
|
G |
Ccne2 |
cyclin E2 |
affects expression |
ISO |
hexyl cinnamic aldehyde affects the expression of CCNE2 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 5:29,082,169...29,094,879
|
|
G |
Ccr4 |
C-C motif chemokine receptor 4 |
affects expression |
ISO |
hexyl cinnamic aldehyde affects the expression of CCR4 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 8:114,176,291...114,182,033
|
|
G |
Ccr7 |
C-C motif chemokine receptor 7 |
decreases expression |
ISO |
hexyl cinnamic aldehyde results in decreased expression of CCR7 protein |
CTD |
PMID:37326882 |
|
NCBI chr10:84,098,193...84,108,309
|
|
G |
Cd160 |
CD160 molecule |
affects expression |
ISO |
hexyl cinnamic aldehyde affects the expression of CD160 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 2:184,340,820...184,383,421
|
|
G |
Cd207 |
CD207 molecule |
affects expression |
ISO |
hexyl cinnamic aldehyde affects the expression of CD207 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 4:116,155,229...116,161,587
|
|
G |
Cd5l |
Cd5 molecule-like |
affects expression |
ISO |
hexyl cinnamic aldehyde affects the expression of CD5L mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 2:172,791,007...172,802,018
|
|
G |
Cd80 |
Cd80 molecule |
multiple interactions increases expression |
ISO |
[hexyl cinnamic aldehyde co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD80 protein hexyl cinnamic aldehyde results in increased expression of CD80 protein |
CTD |
PMID:31958493 |
|
NCBI chr11:75,760,073...75,798,978
|
|
G |
Cd83 |
CD83 molecule |
affects expression |
ISO |
hexyl cinnamic aldehyde affects the expression of CD83 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr17:21,093,281...21,113,223
|
|
G |
Cd86 |
CD86 molecule |
multiple interactions increases expression |
ISO |
[hexyl cinnamic aldehyde co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 protein; PRKCB protein affects the reaction [hexyl cinnamic aldehyde results in increased expression of CD86 protein] |
CTD |
PMID:31958493 PMID:37326882 |
|
NCBI chr11:77,647,565...77,706,178
|
|
G |
Cdc20 |
cell division cycle 20 |
affects expression |
ISO |
hexyl cinnamic aldehyde affects the expression of CDC20 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 5:137,251,596...137,255,799
|
|
G |
Cdc25c |
cell division cycle 25C |
affects expression |
ISO |
hexyl cinnamic aldehyde affects the expression of CDC25C mRNA |
CTD |
PMID:22302311 |
|
NCBI chr18:26,608,483...26,630,292
|
|
G |
Cdk1 |
cyclin-dependent kinase 1 |
affects expression |
ISO |
hexyl cinnamic aldehyde affects the expression of CDK1 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr20:19,265,252...19,280,456
|
|
G |
Cphx1 |
cytoplasmic polyadenylated homeobox 1 |
affects expression |
ISO |
hexyl cinnamic aldehyde affects the expression of CPHX1 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr16:1,533,883...1,537,248
|
|
G |
Ctla4 |
cytotoxic T-lymphocyte-associated protein 4 |
affects expression |
ISO |
hexyl cinnamic aldehyde affects the expression of CTLA4 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 9:69,812,859...69,819,959
|
|
G |
Cxcl14 |
C-X-C motif chemokine ligand 14 |
decreases expression |
ISO |
hexyl cinnamic aldehyde results in decreased expression of CXCL14 protein |
CTD |
PMID:31734321 |
|
NCBI chr17:8,323,150...8,331,176
|
|
G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
increases expression decreases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of CXCL2 mRNA; hexyl cinnamic aldehyde results in increased expression of CXCL2 protein hexyl cinnamic aldehyde results in decreased expression of CXCL2 protein |
CTD |
PMID:23178550 PMID:28826779 |
|
NCBI chr14:17,465,210...17,467,255
|
|
G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of CXCL1 mRNA |
CTD |
PMID:28826779 |
|
NCBI chr14:17,571,900...17,573,624
|
|
G |
Dio2 |
iodothyronine deiodinase 2 |
decreases activity |
ISO |
hexyl cinnamic aldehyde results in decreased activity of DIO2 protein |
CTD |
PMID:30561685 |
|
NCBI chr 6:115,396,308...115,410,594
|
|
G |
Dio3 |
iodothyronine deiodinase 3 |
decreases activity |
ISO |
hexyl cinnamic aldehyde results in decreased activity of DIO3 protein |
CTD |
PMID:30561685 |
|
NCBI chr 6:129,285,747...129,287,608
|
|
G |
E2f1 |
E2F transcription factor 1 |
affects expression |
ISO |
hexyl cinnamic aldehyde affects the expression of E2F1 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 3:163,524,739...163,535,563
|
|
G |
Fabp7 |
fatty acid binding protein 7 |
affects expression |
ISO |
hexyl cinnamic aldehyde affects the expression of FABP7 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr20:37,123,193...37,126,725
|
|
G |
Fech |
ferrochelatase |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of FECH mRNA |
CTD |
PMID:20566472 |
|
NCBI chr18:57,945,123...57,978,327
|
|
G |
Ftl1 |
ferritin light chain 1 |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of FTL mRNA |
CTD |
PMID:20566472 |
|
NCBI chr 1:105,072,858...105,074,705
|
|
G |
Fxyd4 |
FXYD domain-containing ion transport regulator 4 |
affects expression |
ISO |
hexyl cinnamic aldehyde affects the expression of FXYD4 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 4:151,109,779...151,113,659
|
|
G |
G6pd |
glucose-6-phosphate dehydrogenase |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of G6PD mRNA |
CTD |
PMID:20566472 |
|
NCBI chr X:157,352,364...157,372,144
|
|
G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of GCLC mRNA |
CTD |
PMID:20566472 |
|
NCBI chr 8:87,510,251...87,548,896
|
|
G |
Gclm |
glutamate cysteine ligase, modifier subunit |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of GCLM mRNA |
CTD |
PMID:20566472 |
|
NCBI chr 2:213,032,135...213,052,192
|
|
G |
Gpx3 |
glutathione peroxidase 3 |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of GPX3 mRNA |
CTD |
PMID:20566472 |
|
NCBI chr10:39,529,335...39,537,406
|
|
G |
Gsr |
glutathione-disulfide reductase |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of GSR mRNA |
CTD |
PMID:20566472 |
|
NCBI chr16:65,185,574...65,228,742
|
|
G |
Gzmb |
granzyme B |
affects expression |
ISO |
hexyl cinnamic aldehyde affects the expression of GZMB mRNA |
CTD |
PMID:22302311 |
|
NCBI chr15:30,343,352...30,346,814
|
|
G |
Hmox1 |
heme oxygenase 1 |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of HMOX1 mRNA |
CTD |
PMID:20566472 PMID:26244607 |
|
NCBI chr19:13,452,365...13,479,823
|
|
G |
Ifng |
interferon gamma |
increases secretion |
ISO |
hexyl cinnamic aldehyde results in increased secretion of IFNG protein |
CTD |
PMID:22245253 |
|
NCBI chr 7:55,789,180...55,793,216
|
|
G |
Il12b |
interleukin 12B |
affects expression |
ISO |
hexyl cinnamic aldehyde affects the expression of IL12B mRNA |
CTD |
PMID:22302311 |
|
NCBI chr10:29,390,300...29,405,194
|
|
G |
Il17a |
interleukin 17A |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of IL17A mRNA; hexyl cinnamic aldehyde results in increased expression of IL17A protein |
CTD |
PMID:28826779 |
|
NCBI chr 9:30,640,844...30,644,331
|
|
G |
Il1a |
interleukin 1 alpha |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of IL1A protein |
CTD |
PMID:23178550 |
|
NCBI chr 3:136,979,804...136,990,236
|
|
G |
Il2 |
interleukin 2 |
increases secretion increases expression |
ISO |
hexyl cinnamic aldehyde results in increased secretion of IL2 protein hexyl cinnamic aldehyde results in increased expression of IL2 protein |
CTD |
PMID:22245253 PMID:22381623 |
|
NCBI chr 2:121,932,968...121,937,672
|
|
G |
Il21 |
interleukin 21 |
affects expression |
ISO |
hexyl cinnamic aldehyde affects the expression of IL21 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 2:120,117,105...120,127,012
|
|
G |
Il2ra |
interleukin 2 receptor subunit alpha |
affects expression |
ISO |
hexyl cinnamic aldehyde affects the expression of IL2RA mRNA |
CTD |
PMID:22302311 |
|
NCBI chr17:66,849,974...66,898,665
|
|
G |
Il4 |
interleukin 4 |
affects expression multiple interactions |
ISO |
hexyl cinnamic aldehyde affects the expression of IL4 mRNA [hexyl cinnamic aldehyde co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD80 protein; [hexyl cinnamic aldehyde co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 protein |
CTD |
PMID:22302311 PMID:31958493 |
|
NCBI chr10:38,272,003...38,277,549
|
|
G |
Il4r |
interleukin 4 receptor |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of IL4RA protein |
CTD |
PMID:22381623 |
|
NCBI chr 1:180,115,061...180,139,981
|
|
G |
Il6 |
interleukin 6 |
increases secretion |
ISO |
hexyl cinnamic aldehyde results in increased secretion of IL6 protein |
CTD |
PMID:22245253 |
|
NCBI chr 4:5,889,999...5,894,575
|
|
G |
Itgav |
integrin subunit alpha V |
affects expression |
ISO |
hexyl cinnamic aldehyde affects the expression of ITGAV mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 3:89,245,382...89,333,512
|
|
G |
Maff |
MAF bZIP transcription factor F |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of MAFF mRNA |
CTD |
PMID:20566472 |
|
NCBI chr 7:112,792,787...112,804,139
|
|
G |
Mafg |
MAF bZIP transcription factor G |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of MAFG mRNA |
CTD |
PMID:20566472 |
|
NCBI chr10:106,401,633...106,410,159
|
|
G |
Mafk |
MAF bZIP transcription factor K |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of MAFK mRNA |
CTD |
PMID:20566472 |
|
NCBI chr12:14,834,628...14,856,414
|
|
G |
Me1 |
malic enzyme 1 |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of ME1 mRNA |
CTD |
PMID:20566472 |
|
NCBI chr 8:96,429,057...96,540,244
|
|
G |
Mgst1 |
microsomal glutathione S-transferase 1 |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of MGST1 mRNA |
CTD |
PMID:20566472 |
|
NCBI chr 4:171,029,666...171,044,893
|
|
G |
Mir146a |
microRNA 146a |
increases expression multiple interactions |
ISO |
hexyl cinnamic aldehyde results in increased expression of MIR146A mRNA PRKCB protein affects the reaction [hexyl cinnamic aldehyde results in increased expression of MIR146A mRNA] |
CTD |
PMID:37326882 |
|
NCBI chr10:28,349,996...28,350,090
|
|
G |
Mir27a |
microRNA 27a |
decreases expression |
ISO |
hexyl cinnamic aldehyde results in decreased expression of MIR27A mRNA |
CTD |
PMID:37326882 |
|
NCBI chr19:23,954,831...23,954,917
|
|
G |
Mki67 |
marker of proliferation Ki-67 |
affects expression |
ISO |
hexyl cinnamic aldehyde affects the expression of MKI67 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 1:199,926,150...199,952,847
|
|
G |
Mmp10 |
matrix metallopeptidase 10 |
affects expression |
ISO |
hexyl cinnamic aldehyde affects the expression of MMP10 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 8:12,974,707...12,982,613
|
|
G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of NQO1 mRNA |
CTD |
PMID:20566472 |
|
NCBI chr19:52,205,374...52,220,267
|
|
G |
Nts |
neurotensin |
affects expression |
ISO |
hexyl cinnamic aldehyde affects the expression of NTS mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 7:37,564,944...37,574,350
|
|
G |
Pgd |
phosphogluconate dehydrogenase |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of PGD mRNA |
CTD |
PMID:20566472 |
|
NCBI chr 5:159,582,746...159,598,945
|
|
G |
Prkcb |
protein kinase C, beta |
multiple interactions |
ISO |
PRKCB protein affects the reaction [hexyl cinnamic aldehyde results in increased expression of CD86 protein]; PRKCB protein affects the reaction [hexyl cinnamic aldehyde results in increased expression of MIR146A mRNA] |
CTD |
PMID:37326882 |
|
NCBI chr 1:186,263,397...186,594,743
|
|
G |
Ptgr1 |
prostaglandin reductase 1 |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of PTGR1 mRNA |
CTD |
PMID:20566472 |
|
NCBI chr 5:78,579,060...78,597,671
|
|
G |
Sod1 |
superoxide dismutase 1 |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of SOD1 mRNA |
CTD |
PMID:20566472 |
|
NCBI chr11:42,942,742...42,948,399
|
|
G |
Sod2 |
superoxide dismutase 2 |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of SOD2 mRNA |
CTD |
PMID:20566472 |
|
NCBI chr 1:50,043,323...50,050,168
|
|
G |
Sod3 |
superoxide dismutase 3 |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of SOD3 mRNA |
CTD |
PMID:20566472 |
|
NCBI chr14:62,822,865...62,828,602
|
|
G |
Srxn1 |
sulfiredoxin 1 |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of SRXN1 mRNA |
CTD |
PMID:20566472 |
|
NCBI chr 3:161,064,812...161,070,372
|
|
G |
Thbs1 |
thrombospondin 1 |
affects expression |
ISO |
hexyl cinnamic aldehyde affects the expression of THBS1 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 3:125,510,250...125,525,402
|
|
G |
Thbs4 |
thrombospondin 4 |
affects expression |
ISO |
hexyl cinnamic aldehyde affects the expression of THBS4 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 2:23,983,158...24,025,289
|
|
G |
Timd2 |
T-cell immunoglobulin and mucin domain containing 2 |
affects expression |
ISO |
hexyl cinnamic aldehyde affects the expression of TIMD2 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr10:31,060,308...31,101,262
|
|
G |
Tnf |
tumor necrosis factor |
increases expression multiple interactions |
ISO |
hexyl cinnamic aldehyde results in increased expression of TNF mRNA [hexyl cinnamic aldehyde co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD80 protein; [hexyl cinnamic aldehyde co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 protein |
CTD |
PMID:28826779 PMID:31958493 |
|
NCBI chr20:3,626,685...3,629,303
|
|
G |
Trpm6 |
transient receptor potential cation channel, subfamily M, member 6 |
affects expression |
ISO |
hexyl cinnamic aldehyde affects the expression of TRPM6 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 1:225,559,528...225,747,106
|
|
G |
Txn2 |
thioredoxin 2 |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of TXN2 mRNA |
CTD |
PMID:20566472 |
|
NCBI chr 7:111,377,338...111,390,940
|
|
G |
Txnrd1 |
thioredoxin reductase 1 |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of TXNRD1 mRNA |
CTD |
PMID:20566472 |
|
NCBI chr 7:22,717,620...22,802,553
|
|
G |
Txnrd2 |
thioredoxin reductase 2 |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of TXNRD2 mRNA |
CTD |
PMID:20566472 |
|
NCBI chr11:82,519,996...82,568,156
|
|
G |
Ugt1a6 |
UDP glucuronosyltransferase family 1 member A6 |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of UGT1A6 mRNA |
CTD |
PMID:20566472 |
|
NCBI chr 9:96,195,018...96,256,264
|
|
G |
Vegfa |
vascular endothelial growth factor A |
increases expression |
ISO |
hexyl cinnamic aldehyde results in increased expression of VEGFA protein |
CTD |
PMID:25617811 |
|
NCBI chr 9:22,452,854...22,468,194
|
|
|
G |
Il1b |
interleukin 1 beta |
multiple interactions |
EXP |
2-methoxycinnamaldehyde inhibits the reaction [IL1B protein results in increased abundance of Dinoprostone]; 2-methoxycinnamaldehyde inhibits the reaction [IL1B protein results in increased activity of PTGS2 protein]; 2-methoxycinnamaldehyde inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein] |
CTD |
PMID:17077517 |
|
NCBI chr 3:137,030,200...137,036,581
|
|
G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
EXP |
2-methoxycinnamaldehyde inhibits the reaction [IL1B protein results in increased activity of PTGS2 protein]; 2-methoxycinnamaldehyde inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein] |
CTD |
PMID:17077517 |
|
NCBI chr13:64,714,063...64,722,320
|
|
|
G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
increases expression |
ISO |
coniferaldehyde results in increased expression of ABCC2 mRNA |
CTD |
PMID:26275128 |
|
NCBI chr 1:252,613,875...252,672,459
|
|
G |
Abcc3 |
ATP binding cassette subfamily C member 3 |
increases expression |
ISO |
coniferaldehyde results in increased expression of ABCC3 mRNA |
CTD |
PMID:26275128 |
|
NCBI chr10:79,793,571...79,839,528
|
|
G |
Akr1c1 |
aldo-keto reductase family 1, member C1 |
multiple interactions increases expression |
ISO |
NFE2L2 mutant form inhibits the reaction [coniferaldehyde results in increased expression of AKR1C1 protein] coniferaldehyde results in increased expression of AKR1C1 mRNA; coniferaldehyde results in increased expression of AKR1C1 protein |
CTD |
PMID:26275128 |
|
NCBI chr17:70,720,397...70,747,285
|
|
G |
Akr1c2 |
aldo-keto reductase family 1, member C2 |
increases expression |
ISO |
coniferaldehyde results in increased expression of AKR1C2 mRNA; coniferaldehyde results in increased expression of AKR1C2 protein |
CTD |
PMID:26275128 |
|
NCBI chr17:70,669,684...70,717,935
|
|
G |
Akr1c3 |
aldo-keto reductase family 1, member C3 |
increases expression |
ISO |
coniferaldehyde results in increased expression of AKR1C3 mRNA |
CTD |
PMID:26275128 |
|
NCBI chr17:71,020,884...71,037,779
|
|
G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
increases expression |
ISO |
coniferaldehyde results in increased expression of GCLC mRNA |
CTD |
PMID:26275128 |
|
NCBI chr 8:87,510,251...87,548,896
|
|
G |
Gclm |
glutamate cysteine ligase, modifier subunit |
increases expression |
ISO |
coniferaldehyde results in increased expression of GCLM mRNA |
CTD |
PMID:26275128 |
|
NCBI chr 2:213,032,135...213,052,192
|
|
G |
Gsr |
glutathione-disulfide reductase |
increases expression |
ISO |
coniferaldehyde results in increased expression of GSR mRNA coniferaldehyde results in increased expression of GSR protein |
CTD |
PMID:26275128 |
|
NCBI chr16:65,185,574...65,228,742
|
|
G |
Hmox1 |
heme oxygenase 1 |
multiple interactions increases expression |
ISO |
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [coniferaldehyde results in increased expression of HMOX1 protein]; MAPK14 mutant form inhibits the reaction [coniferaldehyde results in increased expression of HMOX1 protein]; MAPKAPK2 mutant form inhibits the reaction [coniferaldehyde results in increased expression of HMOX1 protein]; NFE2L2 mutant form inhibits the reaction [coniferaldehyde results in increased expression of HMOX1 protein]; PKN3 mutant form inhibits the reaction [coniferaldehyde results in increased expression of HMOX1 protein]; Ro 31-8220 inhibits the reaction [coniferaldehyde results in increased expression of HMOX1 protein]; SB 203580 inhibits the reaction [coniferaldehyde results in increased expression of HMOX1 protein] coniferaldehyde results in increased expression of HMOX1 mRNA; coniferaldehyde results in increased expression of HMOX1 protein |
CTD |
PMID:26275128 |
|
NCBI chr19:13,452,365...13,479,823
|
|
G |
Ifng |
interferon gamma |
multiple interactions |
ISO |
coniferaldehyde inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased expression of NOS2 protein]; coniferaldehyde inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased phosphorylation of JAK2 protein]; coniferaldehyde inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased phosphorylation of STAT1 protein] |
CTD |
PMID:27378624 |
|
NCBI chr 7:55,789,180...55,793,216
|
|
G |
Jak2 |
Janus kinase 2 |
multiple interactions |
ISO |
coniferaldehyde inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased phosphorylation of JAK2 protein] coniferaldehyde inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of JAK2 protein] |
CTD |
PMID:27378624 |
|
NCBI chr 1:236,408,905...236,468,769
|
|
G |
Mapk14 |
mitogen activated protein kinase 14 |
multiple interactions |
ISO |
MAPK14 mutant form inhibits the reaction [coniferaldehyde affects the localization of and results in increased phosphorylation of NFE2L2 protein]; MAPK14 mutant form inhibits the reaction [coniferaldehyde results in increased expression of HMOX1 protein] |
CTD |
PMID:26275128 |
|
NCBI chr20:6,751,288...6,812,294
|
|
G |
Mapkapk2 |
MAPK activated protein kinase 2 |
multiple interactions |
ISO |
MAPKAPK2 mutant form inhibits the reaction [coniferaldehyde affects the localization of and results in increased phosphorylation of NFE2L2 protein]; MAPKAPK2 mutant form inhibits the reaction [coniferaldehyde results in increased expression of HMOX1 protein] |
CTD |
PMID:26275128 |
|
NCBI chr13:45,066,027...45,112,326
|
|
G |
Muc5ac |
mucin 5AC, oligomeric mucus/gel-forming |
increases expression multiple interactions |
ISO |
coniferaldehyde results in increased expression of MUC5AC mRNA 2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole inhibits the reaction [coniferaldehyde results in increased expression of MUC5AC mRNA]; A 967079 inhibits the reaction [coniferaldehyde results in increased expression of MUC5AC mRNA]; coniferaldehyde results in increased expression of and results in increased secretion of MUC5AC protein; TWS 119 inhibits the reaction [coniferaldehyde results in increased expression of MUC5AC mRNA] |
CTD |
PMID:31944254 |
|
NCBI chr 1:206,293,717...206,326,006
|
|
G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions increases expression |
ISO |
coniferaldehyde affects the localization of and results in increased phosphorylation of NFE2L2 protein; MAPK14 mutant form inhibits the reaction [coniferaldehyde affects the localization of and results in increased phosphorylation of NFE2L2 protein]; MAPKAPK2 mutant form inhibits the reaction [coniferaldehyde affects the localization of and results in increased phosphorylation of NFE2L2 protein]; NFE2L2 mutant form inhibits the reaction [coniferaldehyde results in increased expression of AKR1C1 protein]; NFE2L2 mutant form inhibits the reaction [coniferaldehyde results in increased expression of HMOX1 protein]; PKN3 mutant form inhibits the reaction [coniferaldehyde affects the localization of and results in increased phosphorylation of NFE2L2 protein] coniferaldehyde results in increased expression of NFE2L2 protein |
CTD |
PMID:26275128 |
|
NCBI chr 3:81,001,529...81,031,165
|
|
G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
ISO |
coniferaldehyde inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased expression of NOS2 protein] coniferaldehyde inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 mRNA]; coniferaldehyde inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 protein] |
CTD |
PMID:27378624 |
|
NCBI chr10:64,313,335...64,349,221
|
|
G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
increases expression |
ISO |
coniferaldehyde results in increased expression of NQO1 protein |
CTD |
PMID:26275128 |
|
NCBI chr19:52,205,374...52,220,267
|
|
G |
Pkn3 |
protein kinase N3 |
multiple interactions |
ISO |
PKN3 mutant form inhibits the reaction [coniferaldehyde affects the localization of and results in increased phosphorylation of NFE2L2 protein]; PKN3 mutant form inhibits the reaction [coniferaldehyde results in increased expression of HMOX1 protein] |
CTD |
PMID:26275128 |
|
NCBI chr 3:33,747,610...33,761,405
|
|
G |
Stat1 |
signal transducer and activator of transcription 1 |
multiple interactions |
ISO |
coniferaldehyde inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased phosphorylation of STAT1 protein] coniferaldehyde inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the localization of STAT1 protein modified form]; coniferaldehyde inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of STAT1 protein] |
CTD |
PMID:27378624 |
|
NCBI chr 9:56,911,522...56,951,926
|
|
G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
coniferaldehyde inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased expression of NOS2 protein]; coniferaldehyde inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased phosphorylation of JAK2 protein]; coniferaldehyde inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased phosphorylation of STAT1 protein] |
CTD |
PMID:27378624 |
|
NCBI chr20:3,626,685...3,629,303
|
|
G |
Trpa1 |
transient receptor potential cation channel, subfamily A, member 1 |
increases activity |
ISO |
coniferaldehyde results in increased activity of TRPA1 protein |
CTD |
PMID:23541125 |
|
NCBI chr 5:9,163,060...9,217,325
|
|
G |
Txnrd1 |
thioredoxin reductase 1 |
increases expression |
ISO |
coniferaldehyde results in increased expression of TXNRD1 mRNA |
CTD |
PMID:26275128 |
|
NCBI chr 7:22,717,620...22,802,553
|
|