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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:UNC1999
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Accession:CHEBI:230504 term browser browse the term
Definition:UNC1999 is a SAM-competitive, potent and selective inhibitor of EZH2/1.
Synonyms:related_synonym: Formula=C33H43N7O2;   InChI=1S/C33H43N7O2/c1-7-8-24-15-23(6)37-33(42)28(24)19-35-32(41)27-16-26(17-30-29(27)20-36-40(30)22(4)5)25-9-10-31(34-18-25)39-13-11-38(12-14-39)21(2)3/h9-10,15-18,20-22H,7-8,11-14,19H2,1-6H3,(H,35,41)(H,37,42);   InChIKey=DPJNKUOXBZSZAI-UHFFFAOYSA-N;   SMILES=O=C1C(CNC(C2=C3C=NN(C(C)C)C3=CC(C4=CN=C(N5CCN(C(C)C)CC5)C=C4)=C2)=O)=C(CCC)C=C(C)N1
 xref: CAS:1431612-23-5
 xref_mesh: MESH:C000619732


show annotations for term's descendants           Sort by:
UNC1999 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxa2 forkhead box A2 multiple interactions ISO UNC1999 inhibits the reaction [Cadmium results in decreased expression of FOXA2 mRNA] CTD PMID:36321828 NCBI chr 3:155,923,305...155,927,508
Ensembl chr 3:155,923,307...155,928,757 		JBrowse link
G Hopx HOP homeobox multiple interactions ISO UNC1999 inhibits the reaction [Cadmium results in decreased expression of HOPX mRNA] CTD PMID:36321828 NCBI chr14:31,410,235...31,437,189
Ensembl chr14:31,410,221...31,437,188 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20871
    chemical entity 20869
      atom 20869
        nonmetal atom 20777
          carbon atom 20721
            organic molecular entity 20721
              UNC1999 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 20871
    subatomic particle 20869
      composite particle 20869
        hadron 20869
          baryon 20869
            nucleon 20869
              atomic nucleus 20869
                atom 20869
                  main group element atom 20792
                    p-block element atom 20792
                      carbon group element atom 20725
                        carbon atom 20721
                          organic molecular entity 20721
                            UNC1999 2
paths to the root