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Pathways

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:carotene
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Accession:CHEBI:23042 term browser browse the term
Definition:Hydrocarbon carotenoids.
Synonyms:related_synonym: carotenes



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8'-apo-beta,psi-caroten-8'-al term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadm acyl-CoA dehydrogenase medium chain increases expression ISO apocarotenal results in increased expression of ACADM mRNA CTD PMID:17034753 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:245,518,693...245,542,864
JBrowse link
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide increases expression ISO apocarotenal results in increased expression of ADH5 mRNA CTD PMID:17034753 NCBI chr 2:226,975,184...226,987,591
Ensembl chr 2:229,648,501...229,665,232
JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 decreases expression ISO apocarotenal results in decreased expression of ALDH1B1 mRNA CTD PMID:17034753 NCBI chr 5:64,859,000...64,864,008
Ensembl chr 5:64,858,934...64,864,365
JBrowse link
G Aldh3b1 aldehyde dehydrogenase 3 family, member B1 decreases expression ISO apocarotenal results in decreased expression of ALDH3B1 mRNA CTD PMID:17034753 NCBI chr 1:201,145,309...201,162,675
Ensembl chr 1:210,573,661...210,610,538
JBrowse link
G Aldh4a1 aldehyde dehydrogenase 4 family, member A1 decreases expression ISO apocarotenal results in decreased expression of ALDH4A1 mRNA CTD PMID:17034753 NCBI chr 5:151,880,002...151,905,491
Ensembl chr 5:157,162,945...157,188,673
JBrowse link
G Ank2 ankyrin 2 increases expression ISO apocarotenal results in increased expression of ANK2 mRNA CTD PMID:17034753 NCBI chr 2:218,052,555...218,628,414
Ensembl chr 2:218,052,555...218,537,259
JBrowse link
G Ank3 ankyrin 3 increases expression ISO apocarotenal results in increased expression of ANK3 mRNA CTD PMID:17034753 NCBI chr20:18,601,307...19,224,790
Ensembl chr20:18,601,826...19,084,879
JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 increases expression ISO apocarotenal results in increased expression of ASAH1 mRNA CTD PMID:17034753 NCBI chr16:50,966,404...50,997,827
Ensembl chr16:57,669,750...57,718,305
JBrowse link
G Asb1 ankyrin repeat and SOCS box-containing 1 increases expression ISO apocarotenal results in increased expression of ASB1 mRNA CTD PMID:17034753 NCBI chr 9:92,120,332...92,140,790
Ensembl chr 9:99,567,867...99,583,907
JBrowse link
G Asb9 ankyrin repeat and SOCS box-containing 9 increases expression ISO apocarotenal results in increased expression of ASB9 mRNA CTD PMID:17034753 NCBI chr  X:29,956,576...30,001,436
Ensembl chr  X:33,588,484...33,624,397
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression ISO apocarotenal results in decreased expression of BAX mRNA CTD PMID:17034753 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Bco2 beta-carotene oxygenase 2 multiple interactions ISO [BCO2 protein results in increased metabolism of beta Carotene] which results in increased chemical synthesis of apocarotenal; [BCO2 protein results in increased metabolism of Cryptoxanthins] which results in increased chemical synthesis of apocarotenal; [BCO2 protein results in increased metabolism of Lutein] which results in increased chemical synthesis of apocarotenal metabolite; [BCO2 protein results in increased metabolism of Zeaxanthins] which results in increased chemical synthesis of apocarotenal metabolite CTD PMID:21106934 NCBI chr 8:50,882,174...50,907,676
Ensembl chr 8:59,778,575...59,799,168
JBrowse link
G Casp8ap2 caspase 8 associated protein 2 increases expression ISO apocarotenal results in increased expression of CASP8AP2 mRNA CTD PMID:17034753 NCBI chr 5:47,014,501...47,052,276
Ensembl chr 5:51,810,972...51,848,632
JBrowse link
G Cdh1 cadherin 1 increases expression ISO apocarotenal results in increased expression of CDH1 mRNA CTD PMID:17034753 NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565
JBrowse link
G Cldn10 claudin 10 increases expression ISO apocarotenal results in increased expression of CLDN10 mRNA CTD PMID:17034753 NCBI chr15:95,862,785...95,954,526
Ensembl chr15:102,269,858...102,361,589
JBrowse link
G Cldn18 claudin 18 increases expression ISO apocarotenal results in increased expression of CLDN18 mRNA CTD PMID:17034753 NCBI chr 8:100,246,499...100,265,797
Ensembl chr 8:109,126,949...109,152,701
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO apocarotenal results in decreased expression of COL1A1 mRNA CTD PMID:17034753 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460
JBrowse link
G Col4a1 collagen type IV alpha 1 chain decreases expression ISO apocarotenal results in decreased expression of COL4A1 mRNA CTD PMID:17034753 NCBI chr16:84,885,597...84,996,482
Ensembl chr16:84,885,597...84,996,482
JBrowse link
G Col4a2 collagen type IV alpha 2 chain decreases expression ISO apocarotenal results in decreased expression of COL4A2 mRNA CTD PMID:17034753 NCBI chr16:78,047,591...78,183,360
Ensembl chr16:84,749,672...84,885,520
JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 decreases expression ISO apocarotenal results in decreased expression of CRABP2 mRNA CTD PMID:17034753 NCBI chr 2:175,714,862...175,719,208
Ensembl chr 2:175,707,312...175,728,385
JBrowse link
G Ctsb cathepsin B decreases expression ISO apocarotenal results in decreased expression of CTSB mRNA CTD PMID:17034753 NCBI chr15:41,565,607...41,586,479
Ensembl chr15:41,565,611...41,586,478
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression ISO apocarotenal results in increased expression of CXCL12 mRNA CTD PMID:17034753 NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 increases expression ISO apocarotenal results in increased expression of CXCL6 mRNA CTD PMID:17034753 NCBI chr14:17,594,959...17,596,417
Ensembl chr14:17,594,959...17,596,417
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 increases expression ISO apocarotenal results in increased expression of CXCL9 mRNA CTD PMID:17034753 NCBI chr14:16,007,166...16,012,077
Ensembl chr14:16,007,204...16,014,299
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO apocarotenal results in increased expression of CXCR4 mRNA CTD PMID:17034753 NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459
JBrowse link
G Dlx2 distal-less homeobox 2 increases expression ISO apocarotenal results in increased expression of DLX2 mRNA CTD PMID:17034753 NCBI chr 3:76,777,912...76,781,255
Ensembl chr 3:76,777,912...76,781,255
JBrowse link
G Dlx4 distal-less homeobox 4 increases expression ISO apocarotenal results in increased expression of DLX4 mRNA CTD PMID:17034753 NCBI chr10:80,085,037...80,090,434
Ensembl chr10:80,582,303...80,587,294
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit decreases expression ISO apocarotenal results in decreased expression of ERCC2 mRNA CTD PMID:17034753 NCBI chr 1:88,161,342...88,175,102
Ensembl chr 1:88,160,988...88,175,102
JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor decreases expression ISO apocarotenal results in decreased expression of ETS1 mRNA CTD PMID:17034753 NCBI chr 8:39,303,936...39,426,022
Ensembl chr 8:39,303,925...39,426,021
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO apocarotenal results in increased expression of FAS mRNA CTD PMID:17034753 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104
JBrowse link
G Fasn fatty acid synthase decreases expression ISO apocarotenal results in decreased expression of FASN mRNA CTD PMID:17034753 NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583
JBrowse link
G Gata6 GATA binding protein 6 increases expression ISO apocarotenal results in increased expression of GATA6 mRNA CTD PMID:17034753 NCBI chr18:2,460,909...2,492,322
Ensembl chr18:2,458,253...2,492,322
JBrowse link
G Gbp1 guanylate binding protein 1 increases expression ISO apocarotenal results in increased expression of GBP1 mRNA CTD PMID:17034753 NCBI chr 2:234,071,366...234,106,012
Ensembl chr 2:234,190,708...234,206,802
Ensembl chr 2:234,190,708...234,206,802
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 decreases expression ISO apocarotenal results in decreased expression of GSTK1 mRNA CTD PMID:17034753 NCBI chr 4:71,118,979...71,123,298
Ensembl chr 4:72,085,531...72,089,927
JBrowse link
G Gstm2 glutathione S-transferase mu 2 decreases expression ISO apocarotenal results in decreased expression of GSTM2 mRNA CTD PMID:17034753 NCBI chr 2:198,312,179...198,316,962 JBrowse link
G Gstm4 glutathione S-transferase mu 4 decreases expression ISO apocarotenal results in decreased expression of GSTM4 mRNA CTD PMID:17034753 NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:198,358,744...198,373,638
JBrowse link
G Gstm5l glutathione S-transferase, mu 5-like increases expression ISO apocarotenal results in increased expression of GSTM5 mRNA CTD PMID:17034753 NCBI chr 2:195,544,424...195,549,895
Ensembl chr 2:198,232,596...198,238,252
JBrowse link
G Gstz1 glutathione S-transferase zeta 1 decreases expression ISO apocarotenal results in decreased expression of GSTZ1 mRNA CTD PMID:17034753 NCBI chr 6:112,525,576...112,536,228
Ensembl chr 6:112,525,377...112,536,233
JBrowse link
G Hoxa7 homeobox A7 increases expression ISO apocarotenal results in increased expression of HOXA7 mRNA CTD PMID:17034753 NCBI chr 4:81,315,730...81,317,629
Ensembl chr 4:82,646,364...82,648,241
JBrowse link
G Hoxb6 homeo box B6 increases expression ISO apocarotenal results in increased expression of HOXB6 mRNA CTD PMID:17034753 NCBI chr10:81,258,726...81,267,458 JBrowse link
G Hoxc10 homeo box C10 increases expression ISO apocarotenal results in increased expression of HOXC10 mRNA CTD PMID:17034753 NCBI chr 7:134,103,741...134,108,966
Ensembl chr 7:135,982,065...135,986,712
JBrowse link
G Irf8 interferon regulatory factor 8 increases expression ISO apocarotenal results in increased expression of IRF8 mRNA CTD PMID:17034753 NCBI chr19:65,699,284...65,721,066
Ensembl chr19:65,699,284...65,721,062
JBrowse link
G Irx4 iroquois homeobox 4 decreases expression ISO apocarotenal results in decreased expression of IRX4 mRNA CTD PMID:17034753 NCBI chr 1:30,030,561...30,039,549
Ensembl chr 1:31,859,101...31,868,089
JBrowse link
G Itgb4 integrin subunit beta 4 decreases expression ISO apocarotenal results in decreased expression of ITGB4 mRNA CTD PMID:17034753 NCBI chr10:101,206,657...101,243,012
Ensembl chr10:101,705,587...101,741,932
JBrowse link
G Ivl involucrin increases expression ISO apocarotenal results in increased expression of IVL mRNA CTD PMID:17034753 NCBI chr 2:180,842,307...180,854,646
Ensembl chr 2:180,842,307...180,846,578
JBrowse link
G Krt17 keratin 17 decreases expression ISO apocarotenal results in decreased expression of KRT17 mRNA CTD PMID:17034753 NCBI chr10:85,178,673...85,183,392
Ensembl chr10:85,679,070...85,683,787
JBrowse link
G Krt2 keratin 2 increases expression ISO apocarotenal results in increased expression of KRT2 mRNA CTD PMID:17034753 NCBI chr 7:132,940,879...132,948,031
Ensembl chr 7:134,819,584...134,827,011
JBrowse link
G Krt7 keratin 7 affects expression ISO apocarotenal affects the expression of KRT7 mRNA CTD PMID:17034753 NCBI chr 7:132,528,881...132,545,052
Ensembl chr 7:134,407,584...134,423,786
JBrowse link
G Lhx3 LIM homeobox 3 increases expression ISO apocarotenal results in increased expression of LHX3 mRNA CTD PMID:17034753 NCBI chr 3:29,424,620...29,432,637
Ensembl chr 3:29,424,620...29,432,637
JBrowse link
G LOC100912356 interferon alpha-1-like increases expression ISO apocarotenal results in increased expression of IFNA5 mRNA CTD PMID:17034753 NCBI chr 5:103,227,820...103,230,500 JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member affects expression ISO apocarotenal affects the expression of MCL1 mRNA CTD PMID:17034753 NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:185,908,168...185,938,782
JBrowse link
G Meis2 Meis homeobox 2 increases expression ISO apocarotenal results in increased expression of MEIS2 mRNA CTD PMID:17034753 NCBI chr 3:102,742,904...102,944,833
Ensembl chr 3:123,197,066...123,397,751
JBrowse link
G Meox1 mesenchyme homeobox 1 increases expression ISO apocarotenal results in increased expression of MEOX1 mRNA CTD PMID:17034753 NCBI chr10:86,818,450...86,837,563
Ensembl chr10:87,318,695...87,337,976
JBrowse link
G Mnx1 motor neuron and pancreas homeobox 1 increases expression ISO apocarotenal results in increased expression of MNX1 mRNA CTD PMID:17034753 NCBI chr 4:5,866,506...5,871,465
Ensembl chr 4:6,541,645...6,546,604
JBrowse link
G Msh5 mutS homolog 5 increases expression ISO apocarotenal results in increased expression of MSH5 mRNA CTD PMID:17034753 NCBI chr20:3,773,867...3,793,337
Ensembl chr20:3,781,578...3,797,994
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming increases expression ISO apocarotenal results in increased expression of MUC5AC mRNA CTD PMID:17034753 NCBI chr 1:206,293,717...206,326,006
Ensembl chr 1:206,293,869...206,326,006
JBrowse link
G Nos1 nitric oxide synthase 1 increases expression ISO apocarotenal results in increased expression of NOS1 mRNA CTD PMID:17034753 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:44,287,614...44,371,837
JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 increases expression ISO apocarotenal results in increased expression of OLR1 mRNA CTD PMID:17034753 NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:164,612,463...164,634,598
JBrowse link
G Pcdhgc3 protocadherin gamma subfamily C, 3 increases expression ISO apocarotenal results in increased expression of PCDHGC3 mRNA CTD PMID:17034753 NCBI chr18:29,633,016...29,667,865 JBrowse link
G Plscr1 phospholipid scramblase 1 increases expression ISO apocarotenal results in increased expression of PLSCR1 mRNA CTD PMID:17034753 NCBI chr 8:92,784,279...92,804,698
Ensembl chr 8:101,664,056...101,684,614
JBrowse link
G Plscr3 phospholipid scramblase 3 increases expression ISO apocarotenal results in increased expression of PLSCR3 mRNA CTD PMID:17034753 NCBI chr10:55,064,349...55,070,120
Ensembl chr10:55,065,345...55,070,369
JBrowse link
G Plscr4 phospholipid scramblase 4 increases expression ISO apocarotenal results in increased expression of PLSCR4 mRNA CTD PMID:17034753 NCBI chr 8:92,987,290...93,026,056
Ensembl chr 8:101,866,888...101,905,831
JBrowse link
G Rad51ap1 RAD51 associated protein 1 increases expression ISO apocarotenal results in increased expression of RAD51AP1 mRNA CTD PMID:17034753 NCBI chr 4:161,445,610...161,458,661
Ensembl chr 4:161,445,512...161,458,680
JBrowse link
G Rad51d RAD51 paralog D increases expression ISO apocarotenal results in increased expression of RAD51D mRNA CTD PMID:17034753 NCBI chr10:67,805,720...67,824,452
Ensembl chr10:68,238,273...68,321,902
JBrowse link
G Rara retinoic acid receptor, alpha decreases expression ISO apocarotenal results in decreased expression of RARA mRNA CTD PMID:17034753 NCBI chr10:84,379,780...84,424,371
Ensembl chr10:84,389,622...84,425,160
JBrowse link
G Rarb retinoic acid receptor, beta increases expression ISO apocarotenal results in increased expression of RARB mRNA CTD PMID:17034753 NCBI chr15:10,837,252...11,482,037
Ensembl chr15:11,131,358...11,482,040
JBrowse link
G Rarres1 retinoic acid receptor responder 1 increases expression ISO apocarotenal results in increased expression of RARRES1 mRNA CTD PMID:17034753 NCBI chr 2:154,059,761...154,094,021
Ensembl chr 2:154,059,761...154,094,024
JBrowse link
G Six6 SIX homeobox 6 increases expression ISO apocarotenal results in increased expression of SIX6 mRNA CTD PMID:17034753 NCBI chr 6:91,634,568...91,639,548
Ensembl chr 6:97,370,435...97,375,415
JBrowse link
G Sod1 superoxide dismutase 1 decreases expression ISO apocarotenal results in decreased expression of SOD1 mRNA CTD PMID:17034753 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399
JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 affects expression ISO apocarotenal affects the expression of SPTLC2 mRNA CTD PMID:17034753 NCBI chr 6:106,948,682...107,031,532
Ensembl chr 6:112,679,623...112,762,640
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression ISO apocarotenal results in increased expression of SREBF1 mRNA CTD PMID:17034753 NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164
JBrowse link
G Tgm4 transglutaminase 4 increases expression ISO apocarotenal results in increased expression of TGM4 mRNA CTD PMID:17034753 NCBI chr 8:122,689,429...122,726,463
Ensembl chr 8:131,566,887...131,603,920
JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 increases expression ISO apocarotenal results in increased expression of TNFRSF9 mRNA CTD PMID:17034753 NCBI chr 5:161,381,662...161,408,003
Ensembl chr 5:166,664,494...166,690,831
JBrowse link
G Tnfsf10 TNF superfamily member 10 increases expression ISO apocarotenal results in increased expression of TNFSF10 mRNA CTD PMID:17034753 NCBI chr 2:112,136,550...112,155,903 JBrowse link
G Txndc9 thioredoxin domain containing 9 increases expression ISO apocarotenal results in increased expression of TXNDC9 mRNA CTD PMID:17034753 NCBI chr 9:40,211,818...40,221,953
Ensembl chr 9:47,707,231...47,880,085
JBrowse link
G Xrcc3 X-ray repair cross complementing 3 increases expression ISO apocarotenal results in increased expression of XRCC3 mRNA CTD PMID:17034753 NCBI chr 6:136,684,558...136,694,822
Ensembl chr 6:136,684,558...136,694,822
JBrowse link
9'-cis-neoxanthin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aifm1 apoptosis inducing factor, mitochondria associated 1 affects localization ISO neoxanthin affects the localization of AIFM1 protein CTD PMID:17186379 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:132,528,107...132,567,237
JBrowse link
G Casp3 caspase 3 multiple interactions ISO neoxanthin results in increased cleavage of and results in increased activity of CASP3 protein CTD PMID:17186379 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Casp8 caspase 8 increases activity ISO neoxanthin results in increased activity of CASP8 protein CTD PMID:17186379 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:67,758,033...67,806,699
JBrowse link
G Casp9 caspase 9 multiple interactions ISO neoxanthin results in increased cleavage of and results in increased activity of CASP9 protein CTD PMID:17186379 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
all-trans-neoxanthin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aifm1 apoptosis inducing factor, mitochondria associated 1 affects localization ISO neoxanthin affects the localization of AIFM1 protein CTD PMID:17186379 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:132,528,107...132,567,237
JBrowse link
G Casp3 caspase 3 multiple interactions ISO neoxanthin results in increased cleavage of and results in increased activity of CASP3 protein CTD PMID:17186379 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Casp8 caspase 8 increases activity ISO neoxanthin results in increased activity of CASP8 protein CTD PMID:17186379 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:67,758,033...67,806,699
JBrowse link
G Casp9 caspase 9 multiple interactions ISO neoxanthin results in increased cleavage of and results in increased activity of CASP9 protein CTD PMID:17186379 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
all-trans-phytoene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 multiple interactions ISO [(all-E) phytoene co-treated with phytofluene] inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:17051425 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO [(all-E) phytoene co-treated with phytofluene] inhibits the reaction [Estradiol results in increased activity of ESR2 protein] CTD PMID:17051425 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709
JBrowse link
all-trans-phytofluene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 multiple interactions ISO [(all-E) phytoene co-treated with phytofluene] inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:17051425 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO [(all-E) phytoene co-treated with phytofluene] inhibits the reaction [Estradiol results in increased activity of ESR2 protein] CTD PMID:17051425 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709
JBrowse link
alpha-carotene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mgmt O-6-methylguanine-DNA methyltransferase affects response to substance ISO MGMT gene SNP affects the susceptibility to alpha-carotene CTD PMID:16014702 NCBI chr 1:201,140,832...201,367,481
Ensembl chr 1:201,140,661...201,367,482
JBrowse link
astaxanthin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aifm1 apoptosis inducing factor, mitochondria associated 1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of AIFM1 mRNA] CTD PMID:16964424 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:132,528,107...132,567,237
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO astaxanthine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased phosphorylation of AKT1 protein] CTD PMID:33008094 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
JBrowse link
G Alb albumin multiple interactions EXP astaxanthine inhibits the reaction [thiacloprid results in decreased expression of ALB protein] CTD PMID:34564187 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of APP mRNA] CTD PMID:16964424 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971
JBrowse link
G Arg1 arginase 1 multiple interactions ISO astaxanthine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of ARG1 mRNA] CTD PMID:33008094 NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:22,295,322...22,307,713
JBrowse link
G Atg12 autophagy related 12 multiple interactions ISO astaxanthine inhibits the reaction [bisphenol A results in increased expression of ATG12 mRNA] CTD PMID:34439521 NCBI chr18:41,638,841...41,649,311
Ensembl chr18:41,635,835...41,649,261
JBrowse link
G Atg14 autophagy related 14 multiple interactions ISO astaxanthine inhibits the reaction [bisphenol A results in increased expression of ATG14 mRNA] CTD PMID:34439521 NCBI chr15:20,795,750...20,827,113
Ensembl chr15:23,275,457...23,306,815
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO astaxanthine inhibits the reaction [Hydrogen Peroxide results in increased expression of BAX mRNA] CTD PMID:33212048 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP astaxanthine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of BCL2 protein] CTD PMID:39873358 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Becn1 beclin 1 multiple interactions ISO astaxanthine inhibits the reaction [bisphenol A results in increased expression of BECN1 mRNA]; astaxanthine inhibits the reaction [bisphenol A results in increased expression of BECN1 protein] CTD PMID:34439521 NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002
JBrowse link
G C1qa complement C1q A chain decreases expression ISO astaxanthine results in decreased expression of C1QA mRNA CTD PMID:19555370 NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:154,417,087...154,427,732
JBrowse link
G Casp3 caspase 3 multiple interactions ISO
EXP
astaxanthine inhibits the reaction [Hydrogen Peroxide results in increased expression of CASP3 mRNA]
astaxanthine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CASP3 protein]
CTD PMID:33212048 PMID:39873358 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Cat catalase multiple interactions ISO
EXP
astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of CAT mRNA]
astaxanthine inhibits the reaction [thiacloprid results in decreased activity of CAT protein]
CTD PMID:16964424 PMID:34564187 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
JBrowse link
G Cntd1 cyclin N-terminal domain containing 1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of CNTD1 mRNA] CTD PMID:16964424 NCBI chr10:86,221,430...86,231,812 JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions EXP astaxanthine inhibits the reaction [IL1B protein results in decreased expression of COL2A1 protein] CTD PMID:36084724 NCBI chr 7:130,977,561...131,006,627
Ensembl chr 7:130,977,561...131,006,627
JBrowse link
G Cox15 cytochrome c oxidase assembly homolog COX15 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX15 mRNA] CTD PMID:16964424 NCBI chr 1:242,605,588...242,622,279
Ensembl chr 1:252,554,811...252,571,471
JBrowse link
G Cox5a cytochrome c oxidase subunit 5A multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX5A mRNA] CTD PMID:16964424 NCBI chr 8:57,922,374...57,933,781
Ensembl chr 8:66,818,196...66,830,279
JBrowse link
G Cox5b cytochrome c oxidase subunit 5B multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX5B mRNA] CTD PMID:16964424 NCBI chr 9:38,921,980...38,923,806
Ensembl chr 9:46,417,838...46,420,403
JBrowse link
G Cox6b1 cytochrome c oxidase subunit 6B1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX6B1 mRNA] CTD PMID:16964424 NCBI chr 1:85,875,080...85,884,081
Ensembl chr 1:95,001,707...95,011,431
Ensembl chr 5:95,001,707...95,011,431
JBrowse link
G Cox6c cytochrome c oxidase subunit 6C multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX6C mRNA] CTD PMID:16964424 NCBI chr 7:67,129,265...67,142,001
Ensembl chr 7:69,014,417...69,027,166
JBrowse link
G Ctss cathepsin S decreases expression ISO astaxanthine results in decreased expression of CTSS mRNA CTD PMID:19555370 NCBI chr 2:185,775,316...185,803,440
Ensembl chr 2:185,775,296...185,803,440
JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions
decreases expression
EXP astaxanthine inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CYBB mRNA]; astaxanthine inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CYBB protein]; tin protoporphyrin IX inhibits the reaction [astaxanthine inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CYBB mRNA]]
astaxanthine results in decreased expression of CYBB mRNA
CTD PMID:23272707 NCBI chr  X:16,030,596...16,065,065
Ensembl chr  X:16,030,596...16,065,065
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
EXP astaxanthine results in increased expression of and results in increased activity of CYP1A1 protein
astaxanthine results in increased expression of CYP1A1 mRNA
CTD PMID:21414371 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
JBrowse link
G Foxo3 forkhead box O3 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of FOXO3 mRNA] CTD PMID:16964424 NCBI chr20:47,251,968...47,348,254
Ensembl chr20:47,255,878...47,346,845
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases activity
multiple interactions
EXP astaxanthine results in increased activity of G6PD protein
[Cadmium co-treated with astaxanthine] results in decreased activity of G6PD protein
CTD PMID:28665548 PMID:29975440 NCBI chr  X:157,352,364...157,372,144
Ensembl chr  X:157,352,373...157,372,144
JBrowse link
G Gfap glial fibrillary acidic protein decreases expression ISO astaxanthine results in decreased expression of GFAP mRNA CTD PMID:19555370 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:88,352,986...88,361,685
JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression
multiple interactions
ISO astaxanthine results in increased expression of GJA1 protein
2-chloro-5-nitrobenzanilide inhibits the reaction [astaxanthine results in increased expression of GJA1 protein]; astaxanthine promotes the reaction [4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in increased expression of GJA1 protein]
CTD PMID:16091010 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689
JBrowse link
G Gna13 G protein subunit alpha 13 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of GNA13 mRNA] CTD PMID:16964424 NCBI chr10:94,837,271...94,870,290
Ensembl chr10:94,836,444...94,874,968
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP astaxanthine inhibits the reaction [thiacloprid results in increased expression of GPT protein] CTD PMID:34564187 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160
JBrowse link
G Gpx3 glutathione peroxidase 3 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of GPX3 mRNA] CTD PMID:16964424 NCBI chr10:39,529,335...39,537,406
Ensembl chr10:39,529,448...39,537,405
JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions
increases expression
EXP
ISO
astaxanthine inhibits the reaction [IL1B protein results in decreased expression of GPX4 protein]
astaxanthine results in increased expression of GPX4 protein
astaxanthine inhibits the reaction [erastin results in decreased expression of GPX4 protein]
CTD PMID:36084724 PMID:37648051 NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:10,300,832...10,303,629
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 multiple interactions EXP [mithramycin A co-treated with astaxanthine] inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GRIN1 protein]; astaxanthine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GRIN1 mRNA]; astaxanthine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GRIN1 protein]; astaxanthine promotes the reaction [mithramycin A inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GRIN1 mRNA]]; astaxanthine promotes the reaction [mithramycin A inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GRIN1 protein]]; mithramycin A promotes the reaction [astaxanthine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GRIN1 mRNA]]; mithramycin A promotes the reaction [astaxanthine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GRIN1 protein]] CTD PMID:23538867 NCBI chr 3:28,501,836...28,528,754
Ensembl chr 3:28,501,836...28,528,754
JBrowse link
G Grn granulin precursor multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of GRN mRNA] CTD PMID:16964424 NCBI chr10:87,887,834...87,893,938
Ensembl chr10:87,886,122...87,893,936
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP astaxanthine inhibits the reaction [Cadmium results in decreased activity of GSR protein] CTD PMID:29975440 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:65,185,574...65,228,394
JBrowse link
G Gstm2 glutathione S-transferase mu 2 multiple interactions
increases expression
ISO [astaxanthine co-treated with Docosahexaenoic Acids] results in increased expression of GSTM2 mRNA; [astaxanthine co-treated with Eicosapentaenoic Acid] results in increased expression of GSTM2 mRNA
astaxanthine results in increased expression of GSTM2 mRNA
CTD PMID:24157545 NCBI chr 2:198,312,179...198,316,962 JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions ISO
EXP
astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of HMGB1 mRNA]
astaxanthine inhibits the reaction [thiacloprid results in increased expression of HMGB1 mRNA]
CTD PMID:16964424 PMID:34564187 NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327
Ensembl chr12:39,039,050...39,041,327
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
decreases expression
EXP
ISO
astaxanthine results in increased expression of HMOX1 protein
astaxanthine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of HMOX1 mRNA]; astaxanthine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of HMOX1 protein]
astaxanthine results in decreased expression of HMOX1 mRNA
[astaxanthine co-treated with Cyclophosphamide] results in increased expression of HMOX1 protein; astaxanthine promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of HMOX1 mRNA]; astaxanthine promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of HMOX1 protein]; tin protoporphyrin IX inhibits the reaction [astaxanthine promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of HMOX1 mRNA]]; tin protoporphyrin IX inhibits the reaction [astaxanthine promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of HMOX1 protein]]
astaxanthine results in increased expression of HMOX1 mRNA
[astaxanthine co-treated with Docosahexaenoic Acids] results in increased expression of HMOX1 mRNA; [astaxanthine co-treated with Eicosapentaenoic Acid] results in increased expression of HMOX1 mRNA; astaxanthine inhibits the reaction [Hydrogen Peroxide results in increased expression of HMOX1 mRNA]
CTD PMID:20038455 PMID:23272707 PMID:24157545 PMID:33008094 PMID:33212048 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
JBrowse link
G Hoxa9 homeobox A9 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of HOXA9 mRNA] CTD PMID:16964424 NCBI chr 4:81,323,235...81,329,344
Ensembl chr 4:82,653,825...82,662,093
JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of IDH1 mRNA] CTD PMID:16964424 NCBI chr 9:74,027,887...74,057,442
Ensembl chr 9:74,027,892...74,049,555
JBrowse link
G Ifng interferon gamma increases expression ISO astaxanthine results in increased expression of IFNG protein CTD PMID:33132140 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
JBrowse link
G Il10 interleukin 10 multiple interactions ISO
EXP
astaxanthine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of IL10 mRNA]
astaxanthine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL10 protein]; astaxanthine inhibits the reaction [thiacloprid results in increased expression of IL10 protein]
CTD PMID:33008094 PMID:34564187 PMID:39873358 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
JBrowse link
G Il11 interleukin 11 increases expression ISO astaxanthine results in increased expression of IL11 protein CTD PMID:33132140 NCBI chr 1:78,098,622...78,104,915
Ensembl chr 1:78,096,930...78,104,915
JBrowse link
G Il1b interleukin 1 beta decreases expression
multiple interactions
ISO
EXP
astaxanthine results in decreased expression of IL1B mRNA; astaxanthine results in decreased expression of IL1B protein
[astaxanthine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL1B protein; astaxanthine inhibits the reaction [IL1B protein results in decreased expression of COL2A1 protein]; astaxanthine inhibits the reaction [IL1B protein results in decreased expression of GPX4 protein]; astaxanthine inhibits the reaction [IL1B protein results in increased expression of MMP13 protein]; astaxanthine inhibits the reaction [IL1B protein results in increased expression of NOS2 protein]; astaxanthine inhibits the reaction [IL1B protein results in increased expression of P53 protein]; astaxanthine inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; astaxanthine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B protein]; astaxanthine inhibits the reaction [thiacloprid results in increased expression of IL1B protein]
astaxanthine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of IL1B mRNA]
CTD PMID:21621527 PMID:33008094 PMID:34564187 PMID:36084724 PMID:39873358 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Il6 interleukin 6 decreases expression
multiple interactions
ISO
EXP
astaxanthine results in decreased expression of IL6 mRNA
[astaxanthine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL6 protein
astaxanthine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of IL6 mRNA]
CTD PMID:21621527 PMID:33008094 PMID:39873358 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Ins1 insulin 1 decreases expression ISO astaxanthine results in decreased expression of INS1 protein CTD PMID:33132140 NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682
JBrowse link
G Lepr leptin receptor multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of AIFM1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of APP mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of CAT mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of CNTD1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX15 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX5A mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX5B mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX6B1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX6C mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of FOXO3 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of GNA13 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of GPX3 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of GRN mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of HMGB1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of HOXA9 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of IDH1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of ND6 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NDUFA1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NDUFA5 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NDUFC2 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NDUFV2 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NME2 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of PPP1CB mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of PRDX1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of RPS2 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of SOD1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of SPP1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of TGM2 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of TKT mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of UBB mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of UQCRB mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of UQCRC2 mRNA] CTD PMID:16964424 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO astaxanthine inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK1 protein] CTD PMID:34439521 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO astaxanthine inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK3 protein] CTD PMID:34439521 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO astaxanthine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased phosphorylation of MAPK8 protein] CTD PMID:33008094 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427
JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions EXP astaxanthine inhibits the reaction [IL1B protein results in increased expression of MMP13 protein] CTD PMID:36084724 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:12,782,813...12,793,105
JBrowse link
G Mt-nd6 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of ND6 mRNA] CTD PMID:16964424 NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
Ensembl chr MT:13,531...14,049
JBrowse link
G Ndufa1 NADH:ubiquinone oxidoreductase subunit A1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NDUFA1 mRNA] CTD PMID:16964424 NCBI chr  X:116,424,223...116,427,875
Ensembl chr  X:121,289,925...121,293,555
JBrowse link
G Ndufa5 NADH:ubiquinone oxidoreductase subunit A5 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NDUFA5 mRNA] CTD PMID:16964424 NCBI chr 4:52,997,327...53,005,685
Ensembl chr 4:53,962,877...53,971,235
JBrowse link
G Ndufc2 NADH:ubiquinone oxidoreductase subunit C2 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NDUFC2 mRNA] CTD PMID:16964424 NCBI chr 1:151,711,965...151,718,188
Ensembl chr 1:161,123,150...161,129,419
JBrowse link
G Ndufv2 NADH:ubiquinone oxidoreductase core subunit V2 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NDUFV2 mRNA] CTD PMID:16964424 NCBI chr 9:105,690,454...105,710,669
Ensembl chr 9:113,137,306...113,157,520
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression
multiple interactions
EXP
ISO
astaxanthine results in increased expression of NFE2L2 protein
astaxanthine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which affects the localization of NFE2L2 protein]
[astaxanthine co-treated with Cyclophosphamide] results in increased expression of NFE2L2 protein; astaxanthine promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NFE2L2 protein]; tin protoporphyrin IX inhibits the reaction [astaxanthine promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NFE2L2 protein]]
astaxanthine results in increased expression of NFE2L2 mRNA
[astaxanthine co-treated with Docosahexaenoic Acids] results in increased expression of NFE2L2 mRNA; [astaxanthine co-treated with Eicosapentaenoic Acid] results in increased expression of NFE2L2 mRNA; astaxanthine promotes the reaction [Hydrogen Peroxide results in increased expression of NFE2L2 mRNA]
CTD PMID:20038455 PMID:23272707 PMID:24157545 PMID:33008094 PMID:33212048 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NME2 mRNA] CTD PMID:16964424 NCBI chr10:78,898,097...78,903,514
Ensembl chr20:11,179,066...11,179,497
Ensembl chr10:11,179,066...11,179,497
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO
EXP
astaxanthine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of NOS2 mRNA]; astaxanthine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of NOS2 protein]
astaxanthine inhibits the reaction [IL1B protein results in increased expression of NOS2 protein]; astaxanthine inhibits the reaction [thiacloprid results in increased expression of NOS2 mRNA]
CTD PMID:33008094 PMID:34564187 PMID:36084724 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases expression
EXP
ISO
[astaxanthine co-treated with Cyclophosphamide] results in increased expression of NQO1 protein
[astaxanthine co-treated with Docosahexaenoic Acids] results in increased expression of NQO1 mRNA; [astaxanthine co-treated with Eicosapentaenoic Acid] results in increased expression of NQO1 mRNA; astaxanthine inhibits the reaction [Hydrogen Peroxide results in increased expression of NQO1 mRNA]
astaxanthine results in increased expression of NQO1 mRNA
astaxanthine results in increased expression of NQO1 protein
CTD PMID:20038455 PMID:24157545 PMID:33212048 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
JBrowse link
G P2rx7 purinergic receptor P2X 7 multiple interactions EXP astaxanthine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of P2RX7 protein] CTD PMID:39873358 NCBI chr12:39,550,531...39,594,984
Ensembl chr12:39,540,567...39,595,193
JBrowse link
G Pah phenylalanine hydroxylase decreases expression ISO astaxanthine results in decreased expression of PAH mRNA CTD PMID:19555370 NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:23,792,781...23,885,627
JBrowse link
G Pgd phosphogluconate dehydrogenase increases activity EXP astaxanthine results in increased activity of PGD protein CTD PMID:28665548 PMID:29975440 NCBI chr 5:164,865,830...164,882,029
Ensembl chr 5:164,865,830...164,882,029
JBrowse link
G Por cytochrome p450 oxidoreductase decreases activity
increases expression
EXP astaxanthine results in decreased activity of POR protein
astaxanthine results in increased expression of POR protein
CTD PMID:21414371 NCBI chr12:26,587,674...26,655,612
Ensembl chr12:26,587,674...26,635,809
JBrowse link
G Ppp1cb protein phosphatase 1 catalytic subunit beta multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of PPP1CB mRNA] CTD PMID:16964424 NCBI chr 6:29,681,099...29,712,835
Ensembl chr 6:29,681,100...29,712,924
JBrowse link
G Prdx1 peroxiredoxin 1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of PRDX1 mRNA] CTD PMID:16964424 NCBI chr 5:135,383,906...135,399,504
Ensembl chr 5:135,383,906...135,399,504
JBrowse link
G Pten phosphatase and tensin homolog multiple interactions ISO astaxanthine inhibits the reaction [Hydrogen Peroxide results in increased expression of PTEN mRNA] CTD PMID:33212048 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:240,043,707...240,110,330
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression
multiple interactions
ISO
EXP
astaxanthine results in decreased expression of PTGS2 mRNA
astaxanthine inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]
astaxanthine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of PTGS2 mRNA]
CTD PMID:21621527 PMID:33008094 PMID:36084724 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO
EXP
astaxanthine inhibits the reaction [bisphenol A results in increased phosphorylation of RELA protein]
astaxanthine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of RELA protein]
CTD PMID:34439521 PMID:39873358 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
G Rps2 ribosomal protein S2 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of RPS2 mRNA] CTD PMID:16964424 NCBI chr10:13,747,316...13,749,165
Ensembl chr10:14,251,380...14,253,695
JBrowse link
G Skap2 src kinase associated phosphoprotein 2 decreases expression ISO astaxanthine results in decreased expression of SKAP2 mRNA CTD PMID:19555370 NCBI chr 4:80,948,832...81,100,900
Ensembl chr 4:82,263,709...82,432,886
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of SOD1 mRNA] CTD PMID:16964424 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399
JBrowse link
G Sp1 Sp1 transcription factor multiple interactions EXP [mithramycin A co-treated with astaxanthine] inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of and affects the localization of SP1 protein]; astaxanthine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SP1 mRNA]; astaxanthine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SP1 protein]; astaxanthine promotes the reaction [mithramycin A inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SP1 mRNA]]; astaxanthine promotes the reaction [mithramycin A inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SP1 protein]]; mithramycin A promotes the reaction [astaxanthine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SP1 mRNA]]; mithramycin A promotes the reaction [astaxanthine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SP1 protein]] CTD PMID:23538867 NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:135,420,050...135,450,513
JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of SPP1 mRNA] CTD PMID:16964424 NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820
JBrowse link
G Tgm2 transglutaminase 2 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of TGM2 mRNA] CTD PMID:16964424 NCBI chr 3:167,192,612...167,221,845
Ensembl chr 3:167,192,612...167,304,240
JBrowse link
G Tkt transketolase multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of TKT mRNA] CTD PMID:16964424 NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,729,991...5,756,431
JBrowse link
G Tlr2 toll-like receptor 2 multiple interactions ISO astaxanthine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of TLR2 mRNA] CTD PMID:33008094 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:171,497,060...171,520,194
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO astaxanthine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of TLR4 mRNA] CTD PMID:33008094 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007
JBrowse link
G Tnf tumor necrosis factor decreases expression
multiple interactions
increases expression
ISO
EXP
astaxanthine results in decreased expression of TNF protein
astaxanthine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]
astaxanthine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of TNF mRNA]
astaxanthine results in increased expression of TNF protein
CTD PMID:21621527 PMID:33008094 PMID:33132140 PMID:39873358 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tp53 tumor protein p53 multiple interactions EXP astaxanthine inhibits the reaction [Cyclophosphamide results in increased expression of TP53 protein] CTD PMID:20038455 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 multiple interactions ISO astaxanthine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of TREM2 mRNA] CTD PMID:33008094 NCBI chr 9:20,145,215...20,151,797
Ensembl chr 9:20,144,334...20,151,779
JBrowse link
G Ubb ubiquitin B multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of UBB mRNA] CTD PMID:16964424 NCBI chr10:47,746,923...47,748,628
Ensembl chr10:47,727,701...47,750,335
JBrowse link
G Uqcrb ubiquinol-cytochrome c reductase binding protein multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of UQCRB mRNA] CTD PMID:16964424 NCBI chr 7:63,814,784...63,820,150
Ensembl chr 7:65,700,029...65,705,558
JBrowse link
G Uqcrc2 ubiquinol cytochrome c reductase core protein 2 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of UQCRC2 mRNA] CTD PMID:16964424 NCBI chr 1:175,167,933...175,198,499
Ensembl chr 1:184,599,212...184,630,946
JBrowse link
beta-carotene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acad9 acyl-CoA dehydrogenase family, member 9 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ACAD9 mRNA CTD PMID:24657404 NCBI chr 2:118,943,170...118,966,150
Ensembl chr 2:120,871,227...120,894,709
JBrowse link
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide increases expression ISO beta Carotene results in increased expression of ADH5 mRNA CTD PMID:17034753 NCBI chr 2:226,975,184...226,987,591
Ensembl chr 2:229,648,501...229,665,232
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression ISO beta Carotene results in decreased expression of ADIPOQ mRNA CTD PMID:21569430 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:91,226,180...91,240,169
JBrowse link
G Aebp1 AE binding protein 1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of AEBP1 mRNA CTD PMID:24657404 NCBI chr14:80,738,800...80,748,878
Ensembl chr14:84,952,822...84,962,843
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
decreases expression
ISO beta Carotene results in decreased phosphorylation of AKT1 protein
beta Carotene results in decreased expression of AKT1 mRNA
CTD PMID:26733226 PMID:36819991 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
JBrowse link
G Alad aminolevulinate dehydratase multiple interactions ISO beta Carotene inhibits the reaction [arsenic trioxide results in decreased expression of ALAD protein] CTD PMID:25542264 NCBI chr 5:80,977,562...80,987,901
Ensembl chr 5:80,977,562...80,988,041
JBrowse link
G Aldh3b1 aldehyde dehydrogenase 3 family, member B1 decreases expression ISO beta Carotene results in decreased expression of ALDH3B1 mRNA CTD PMID:17034753 NCBI chr 1:201,145,309...201,162,675
Ensembl chr 1:210,573,661...210,610,538
JBrowse link
G Aldh4a1 aldehyde dehydrogenase 4 family, member A1 decreases expression ISO beta Carotene results in decreased expression of ALDH4A1 mRNA CTD PMID:17034753 NCBI chr 5:151,880,002...151,905,491
Ensembl chr 5:157,162,945...157,188,673
JBrowse link
G Ank2 ankyrin 2 increases expression ISO beta Carotene results in increased expression of ANK2 mRNA CTD PMID:17034753 NCBI chr 2:218,052,555...218,628,414
Ensembl chr 2:218,052,555...218,537,259
JBrowse link
G Ank3 ankyrin 3 increases expression ISO beta Carotene results in increased expression of ANK3 mRNA CTD PMID:17034753 NCBI chr20:18,601,307...19,224,790
Ensembl chr20:18,601,826...19,084,879
JBrowse link
G Appbp2 amyloid beta precursor protein binding protein 2 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of APPBP2 mRNA CTD PMID:24657404 NCBI chr10:70,057,774...70,099,877
Ensembl chr10:70,555,212...70,597,193
JBrowse link
G Arhgap26 Rho GTPase activating protein 26 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ARHGAP26 mRNA CTD PMID:24657404 NCBI chr18:30,835,806...31,237,945
Ensembl chr18:31,089,787...31,489,047
JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 increases expression ISO beta Carotene results in increased expression of ASAH1 mRNA CTD PMID:17034753 NCBI chr16:50,966,404...50,997,827
Ensembl chr16:57,669,750...57,718,305
JBrowse link
G Asb1 ankyrin repeat and SOCS box-containing 1 increases expression ISO beta Carotene results in increased expression of ASB1 mRNA CTD PMID:17034753 NCBI chr 9:92,120,332...92,140,790
Ensembl chr 9:99,567,867...99,583,907
JBrowse link
G Asb9 ankyrin repeat and SOCS box-containing 9 increases expression ISO beta Carotene results in increased expression of ASB9 mRNA CTD PMID:17034753 NCBI chr  X:29,956,576...30,001,436
Ensembl chr  X:33,588,484...33,624,397
JBrowse link
G Atp8b1 ATPase phospholipid transporting 8B1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ATP8B1 mRNA CTD PMID:24657404 NCBI chr18:58,016,382...58,157,213
Ensembl chr18:60,288,464...60,427,027
JBrowse link
G Bag3 BAG cochaperone 3 decreases expression ISO beta Carotene results in decreased expression of BAG3 mRNA CTD PMID:17034753 NCBI chr 1:192,533,460...192,557,281
Ensembl chr 1:192,475,828...192,557,280
JBrowse link
G Bag4 BAG cochaperone 4 decreases expression ISO beta Carotene results in decreased expression of BAG4 mRNA CTD PMID:17034753 NCBI chr16:72,991,407...73,008,620
Ensembl chr16:72,991,362...73,013,273
JBrowse link
G Bag5 BAG cochaperone 5 decreases expression ISO beta Carotene results in decreased expression of BAG5 mRNA CTD PMID:17034753 NCBI chr 6:130,768,467...130,772,122
Ensembl chr 6:136,584,741...136,598,492
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
increases expression
ISO beta Carotene results in decreased expression of BAX mRNA
beta Carotene results in increased expression of BAX mRNA; beta Carotene results in increased expression of BAX protein
CTD PMID:15949688 PMID:17034753 PMID:26733226 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO beta Carotene results in decreased expression of BCL2 protein CTD PMID:26733226 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Bco1 beta-carotene oxygenase 1 multiple interactions
affects response to substance
increases oxidation
increases expression
ISO
EXP
beta Carotene results in increased expression of and results in increased activity of BCO1 protein
[BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ACAD9 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of AEBP1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of APPBP2 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ARHGAP26 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ATP8B1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of CDCA8 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of CENPE mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of CLCN3 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of COQ7 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of CTNNAL1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of DHFR mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of DTWD2 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of EDN1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of EIF2S1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of FOXM1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of FZD6 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of IRX4 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ITM2A mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of KIF11 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of LANCL1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of LMNB2 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of METTL21A mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of METTL9 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of MRPL57 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of MTCH2 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of NCKAP1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of NOM1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of PARD6A mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of PCDH1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of PLAT mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of RPP14 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of RRM1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TFCP2 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of THOC7 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TMEM209 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TTC21B mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TWF1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TYMP mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of YTHDC2 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ZDHHC3 mRNA
BCO1 protein results in increased oxidation of beta Carotene
beta Carotene results in increased expression of BCO1 mRNA
Ascorbic Acid inhibits the reaction [Oxidants inhibits the reaction [BCO1 protein results in increased oxidation of beta Carotene]]; Oxidants inhibits the reaction [BCO1 protein results in increased oxidation of beta Carotene]; Vitamin E inhibits the reaction [Oxidants inhibits the reaction [BCO1 protein results in increased oxidation of beta Carotene]]
CTD PMID:9526112 PMID:16186334 PMID:24657404 NCBI chr19:45,149,250...45,186,102
Ensembl chr19:62,058,089...62,094,917
JBrowse link
G Bco2 beta-carotene oxygenase 2 multiple interactions
increases metabolic processing
ISO [BCO2 protein results in increased metabolism of beta Carotene] which results in increased chemical synthesis of apocarotenal CTD PMID:21106934 NCBI chr 8:50,882,174...50,907,676
Ensembl chr 8:59,778,575...59,799,168
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO alpha-Tocopherol promotes the reaction [beta Carotene metabolite results in decreased activity of CASP3 protein]
beta Carotene metabolite results in increased activity of CASP3 protein; beta Carotene results in increased activity of CASP3 protein
CTD PMID:17618090 PMID:26733226 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Cat catalase multiple interactions EXP
ISO
[Ascorbic Acid co-treated with beta Carotene co-treated with alpha-Tocopherol co-treated with Sodium Selenite] inhibits the reaction [Galactosamine results in increased activity of CAT protein]; beta Carotene inhibits the reaction [cholestane-3,5,6-triol results in decreased activity of CAT protein]; beta Carotene inhibits the reaction [Indomethacin results in decreased expression of CAT protein]
beta Carotene inhibits the reaction [arsenic trioxide results in decreased activity of CAT protein]
CTD PMID:9306888 PMID:12500499 PMID:25542264 PMID:31022331 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
JBrowse link
G Cav1 caveolin 1 decreases expression ISO beta Carotene results in decreased expression of CAV1 protein CTD PMID:26733226 NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:46,600,738...46,639,740
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO beta Carotene results in decreased expression of CCND1 protein CTD PMID:26733226 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
JBrowse link
G Cdca8 cell division cycle associated 8 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of CDCA8 mRNA CTD PMID:24657404 NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:142,461,084...142,483,283
JBrowse link
G Cdh1 cadherin 1 increases expression ISO beta Carotene results in increased expression of CDH1 mRNA; beta Carotene results in increased expression of CDH1 protein CTD PMID:17034753 PMID:26733226 NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression ISO beta Carotene results in decreased expression of CEBPA mRNA CTD PMID:21569430 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:96,896,171...96,899,309
JBrowse link
G Cenpe centromere protein E multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of CENPE mRNA CTD PMID:24657404 NCBI chr 2:226,310,970...226,369,636
Ensembl chr 2:226,300,798...226,369,636
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression ISO beta Carotene results in increased expression of CFLAR mRNA CTD PMID:17034753 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:67,679,559...67,726,434
JBrowse link
G Clcn3 chloride voltage-gated channel 3 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of CLCN3 mRNA CTD PMID:24657404 NCBI chr16:29,127,152...29,200,133
Ensembl chr16:34,137,952...34,210,984
JBrowse link
G Cldn10 claudin 10 increases expression ISO beta Carotene results in increased expression of CLDN10 mRNA CTD PMID:17034753 NCBI chr15:95,862,785...95,954,526
Ensembl chr15:102,269,858...102,361,589
JBrowse link
G Cldn18 claudin 18 increases expression ISO beta Carotene results in increased expression of CLDN18 mRNA CTD PMID:17034753 NCBI chr 8:100,246,499...100,265,797
Ensembl chr 8:109,126,949...109,152,701
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO beta Carotene results in decreased expression of COL1A1 mRNA CTD PMID:17034753 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460
JBrowse link
G Col4a1 collagen type IV alpha 1 chain decreases expression ISO beta Carotene results in decreased expression of COL4A1 mRNA CTD PMID:17034753 NCBI chr16:84,885,597...84,996,482
Ensembl chr16:84,885,597...84,996,482
JBrowse link
G Col4a2 collagen type IV alpha 2 chain decreases expression ISO beta Carotene results in decreased expression of COL4A2 mRNA CTD PMID:17034753 NCBI chr16:78,047,591...78,183,360
Ensembl chr16:84,749,672...84,885,520
JBrowse link
G Coq7 coenzyme Q7, hydroxylase multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of COQ7 mRNA CTD PMID:24657404 NCBI chr 1:172,836,359...172,851,173
Ensembl chr 1:182,269,399...182,285,508
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B decreases expression ISO beta Carotene results in decreased expression of CPT1B mRNA CTD PMID:21569430 NCBI chr 7:122,370,974...122,380,473
Ensembl chr 7:122,370,444...122,380,036
JBrowse link
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain increases expression ISO beta Carotene results in increased expression of CRADD mRNA CTD PMID:17034753 NCBI chr 7:29,940,240...29,952,907
Ensembl chr 7:31,685,622...31,874,512
JBrowse link
G Ctnnal1 catenin alpha-like 1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of CTNNAL1 mRNA CTD PMID:24657404 NCBI chr 5:71,514,340...71,569,431
Ensembl chr 5:76,309,546...76,364,637
JBrowse link
G Ctsb cathepsin B decreases expression ISO beta Carotene results in decreased expression of CTSB mRNA CTD PMID:17034753 NCBI chr15:41,565,607...41,586,479
Ensembl chr15:41,565,611...41,586,478
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression ISO beta Carotene results in increased expression of CXCL12 mRNA CTD PMID:17034753 NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 increases expression ISO beta Carotene results in increased expression of CXCL6 mRNA CTD PMID:17034753 NCBI chr14:17,594,959...17,596,417
Ensembl chr14:17,594,959...17,596,417
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 increases expression ISO beta Carotene results in increased expression of CXCL9 mRNA CTD PMID:17034753 NCBI chr14:16,007,166...16,012,077
Ensembl chr14:16,007,204...16,014,299
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO beta Carotene results in increased expression of CXCR4 mRNA CTD PMID:17034753 NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO beta Carotene promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]; Quercetin inhibits the reaction [beta Carotene promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]] CTD PMID:16970932 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 increases expression ISO beta Carotene results in increased expression of CYP26A1 mRNA CTD PMID:16186334 PMID:22542753 NCBI chr 1:244,883,822...244,887,657
Ensembl chr 1:244,883,752...244,887,657
JBrowse link
G Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 increases expression ISO beta Carotene results in increased expression of CYP3A43 mRNA CTD PMID:17034753 NCBI chr12:8,880,509...8,930,382
Ensembl chr12:13,994,311...14,045,788
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO beta Carotene promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA] CTD PMID:16632523 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
JBrowse link
G Dhfr dihydrofolate reductase multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of DHFR mRNA CTD PMID:24657404 NCBI chr 2:23,585,876...23,611,199 JBrowse link
G Dlx2 distal-less homeobox 2 increases expression ISO beta Carotene results in increased expression of DLX2 mRNA CTD PMID:17034753 NCBI chr 3:76,777,912...76,781,255
Ensembl chr 3:76,777,912...76,781,255
JBrowse link
G Dlx4 distal-less homeobox 4 increases expression ISO beta Carotene results in increased expression of DLX4 mRNA CTD PMID:17034753 NCBI chr10:80,085,037...80,090,434
Ensembl chr10:80,582,303...80,587,294
JBrowse link
G Dpp4 dipeptidylpeptidase 4 multiple interactions ISO [Xiao-Ke-An results in increased abundance of beta Carotene] which results in decreased activity of DPP4 protein CTD PMID:32535096 NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:67,370,804...67,452,422
JBrowse link
G Dtwd2 DTW domain containing 2 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of DTWD2 mRNA CTD PMID:24657404 NCBI chr18:42,811,783...42,902,040
Ensembl chr18:45,003,644...45,088,419
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of EDN1 mRNA CTD PMID:24657404 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of EIF2S1 mRNA CTD PMID:24657404 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:103,405,788...103,431,649
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit decreases expression ISO beta Carotene results in decreased expression of ERCC2 mRNA CTD PMID:17034753 NCBI chr 1:88,161,342...88,175,102
Ensembl chr 1:88,160,988...88,175,102
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO beta Carotene inhibits the reaction [Estradiol results in increased activity of ESR1 protein]; beta Carotene inhibits the reaction [Genistein results in increased activity of ESR1 protein]; beta Carotene inhibits the reaction [Paclitaxel results in increased expression of ESR1 mRNA] CTD PMID:17051425 PMID:19340624 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO beta Carotene inhibits the reaction [Estradiol results in increased activity of ESR2 protein]; beta Carotene inhibits the reaction [Genistein results in increased activity of ESR2 protein] CTD PMID:17051425 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709
JBrowse link
G Fabp4 fatty acid binding protein 4 decreases expression ISO beta Carotene results in decreased expression of FABP4 mRNA CTD PMID:21569430 NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:93,488,271...93,492,972
JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 increases expression ISO beta Carotene results in increased expression of FAIM2 mRNA CTD PMID:17034753 NCBI chr 7:130,632,368...130,659,353
Ensembl chr 7:132,512,210...132,538,026
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO beta Carotene results in increased expression of FAS mRNA CTD PMID:17034753 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO beta Carotene results in increased expression of FOSL1 protein CTD PMID:20025956 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:212,183,833...212,192,391
JBrowse link
G Foxa1 forkhead box A1 increases expression ISO beta Carotene results in increased expression of FOXA1 mRNA CTD PMID:17034753 NCBI chr 6:80,838,380...80,871,195
Ensembl chr 6:80,800,960...80,871,191
JBrowse link
G Foxm1 forkhead box M1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of FOXM1 mRNA CTD PMID:24657404 NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:163,325,614...163,337,172
JBrowse link
G Fzd6 frizzled class receptor 6 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of FZD6 mRNA CTD PMID:24657404 NCBI chr 7:71,939,916...71,971,685
Ensembl chr 7:71,939,973...71,971,680
JBrowse link
G Gata6 GATA binding protein 6 increases expression ISO beta Carotene results in increased expression of GATA6 mRNA CTD PMID:17034753 NCBI chr18:2,460,909...2,492,322
Ensembl chr18:2,458,253...2,492,322
JBrowse link
G Gbp1 guanylate binding protein 1 increases expression ISO beta Carotene results in increased expression of GBP1 mRNA CTD PMID:17034753 NCBI chr 2:234,071,366...234,106,012
Ensembl chr 2:234,190,708...234,206,802
Ensembl chr 2:234,190,708...234,206,802
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions
increases expression
ISO
EXP
beta Carotene promotes the reaction [4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in increased expression of GJA1 protein]; Ro 41-5253 inhibits the reaction [beta Carotene results in increased expression of GJA1 protein]
beta Carotene inhibits the reaction [Hydrogen Peroxide results in decreased expression of GJA1 mRNA]; beta Carotene inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of GJA1 protein]
CTD PMID:16091010 PMID:27154496 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO beta Carotene inhibits the reaction [arsenic trioxide results in decreased activity of GSR protein] CTD PMID:25542264 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:65,185,574...65,228,394
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 decreases expression ISO beta Carotene results in decreased expression of GSTK1 mRNA CTD PMID:17034753 NCBI chr 4:71,118,979...71,123,298
Ensembl chr 4:72,085,531...72,089,927
JBrowse link
G Gstm2 glutathione S-transferase mu 2 increases expression ISO beta Carotene results in increased expression of GSTM2 mRNA CTD PMID:17034753 NCBI chr 2:198,312,179...198,316,962 JBrowse link
G Gstm4 glutathione S-transferase mu 4 decreases expression ISO beta Carotene results in decreased expression of GSTM4 mRNA CTD PMID:17034753 NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:198,358,744...198,373,638
JBrowse link
G Gstm5l glutathione S-transferase, mu 5-like increases expression ISO beta Carotene results in increased expression of GSTM5 mRNA CTD PMID:17034753 NCBI chr 2:195,544,424...195,549,895
Ensembl chr 2:198,232,596...198,238,252
JBrowse link
G Gstz1 glutathione S-transferase zeta 1 decreases expression ISO beta Carotene results in decreased expression of GSTZ1 mRNA CTD PMID:17034753 NCBI chr 6:112,525,576...112,536,228
Ensembl chr 6:112,525,377...112,536,233
JBrowse link
G Hoxa7 homeobox A7 increases expression ISO beta Carotene results in increased expression of HOXA7 mRNA CTD PMID:17034753 NCBI chr 4:81,315,730...81,317,629
Ensembl chr 4:82,646,364...82,648,241
JBrowse link
G Hoxb6 homeo box B6 increases expression ISO beta Carotene results in increased expression of HOXB6 mRNA CTD PMID:17034753 NCBI chr10:81,258,726...81,267,458 JBrowse link
G Hoxc10 homeo box C10 increases expression ISO beta Carotene results in increased expression of HOXC10 mRNA CTD PMID:17034753 NCBI chr 7:134,103,741...134,108,966
Ensembl chr 7:135,982,065...135,986,712
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 multiple interactions EXP beta Carotene inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of HPRT1 gene] CTD PMID:12467141 NCBI chr  X:137,655,744...137,687,718
Ensembl chr  X:137,655,680...137,687,712
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 multiple interactions EXP [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of IGFBP5 mRNA CTD PMID:23859036 NCBI chr 9:81,901,605...81,914,187
Ensembl chr 9:81,897,616...81,914,390
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO beta Carotene promotes the reaction [Benzo(a)pyrene results in increased secretion of IL1B protein]; pyrazolanthrone inhibits the reaction [beta Carotene promotes the reaction [Benzo(a)pyrene results in increased secretion of IL1B protein]]; Quercetin inhibits the reaction [beta Carotene promotes the reaction [Benzo(a)pyrene results in increased secretion of IL1B protein]] CTD PMID:21447443 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Irf8 interferon regulatory factor 8 increases expression ISO beta Carotene results in increased expression of IRF8 mRNA CTD PMID:17034753 NCBI chr19:65,699,284...65,721,066
Ensembl chr19:65,699,284...65,721,062
JBrowse link
G Irx4 iroquois homeobox 4 decreases expression
multiple interactions
ISO beta Carotene results in decreased expression of IRX4 mRNA
[BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of IRX4 mRNA
CTD PMID:17034753 PMID:24657404 NCBI chr 1:30,030,561...30,039,549
Ensembl chr 1:31,859,101...31,868,089
JBrowse link
G Itgb1 integrin subunit beta 1 decreases expression ISO beta Carotene results in decreased expression of ITGB1 mRNA CTD PMID:17034753 NCBI chr19:73,602,277...73,650,271
Ensembl chr19:73,602,126...73,650,269
JBrowse link
G Itgb4 integrin subunit beta 4 decreases expression ISO beta Carotene results in decreased expression of ITGB4 mRNA CTD PMID:17034753 NCBI chr10:101,206,657...101,243,012
Ensembl chr10:101,705,587...101,741,932
JBrowse link
G Itm2a integral membrane protein 2A multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ITM2A mRNA CTD PMID:24657404 NCBI chr  X:72,486,383...72,492,344
Ensembl chr  X:76,559,181...76,565,437
JBrowse link
G Ivl involucrin increases expression ISO beta Carotene results in increased expression of IVL mRNA CTD PMID:17034753 NCBI chr 2:180,842,307...180,854,646
Ensembl chr 2:180,842,307...180,846,578
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO beta Carotene results in increased expression of JUN protein CTD PMID:20025956 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285
JBrowse link
G Kif11 kinesin family member 11 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of KIF11 mRNA CTD PMID:24657404 NCBI chr 1:244,494,916...244,589,250
Ensembl chr 1:244,494,875...244,589,250
JBrowse link
G Krt18 keratin 18 increases expression ISO beta Carotene results in increased expression of KRT18 mRNA CTD PMID:17034753 NCBI chr 7:135,036,168...135,039,844
Ensembl chr 7:135,035,982...135,039,848
Ensembl chr10:135,035,982...135,039,848
JBrowse link
G Krt19 keratin 19 increases expression ISO beta Carotene results in increased expression of KRT19 mRNA CTD PMID:17034753 NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,576,235...85,580,952
JBrowse link
G Krt2 keratin 2 increases expression ISO beta Carotene results in increased expression of KRT2 mRNA CTD PMID:17034753 NCBI chr 7:132,940,879...132,948,031
Ensembl chr 7:134,819,584...134,827,011
JBrowse link
G Krt7 keratin 7 affects expression ISO beta Carotene affects the expression of KRT7 mRNA CTD PMID:17034753 NCBI chr 7:132,528,881...132,545,052
Ensembl chr 7:134,407,584...134,423,786
JBrowse link
G Krt8 keratin 8 decreases expression ISO beta Carotene results in decreased expression of KRT8 mRNA CTD PMID:17034753 NCBI chr 7:135,002,886...135,010,339
Ensembl chr 7:135,002,894...135,010,403
JBrowse link
G Lancl1 LanC like glutathione S-transferase 1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of LANCL1 mRNA CTD PMID:24657404 NCBI chr 9:68,515,052...68,548,646
Ensembl chr 9:75,968,286...76,003,475
JBrowse link
G Lhx3 LIM homeobox 3 increases expression ISO beta Carotene results in increased expression of LHX3 mRNA CTD PMID:17034753 NCBI chr 3:29,424,620...29,432,637
Ensembl chr 3:29,424,620...29,432,637
JBrowse link
G Lmnb2 lamin B2 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of LMNB2 mRNA CTD PMID:24657404 NCBI chr 7:8,792,628...8,808,665
Ensembl chr 7:9,440,128...9,459,342
JBrowse link
G LOC100912356 interferon alpha-1-like increases expression ISO beta Carotene results in increased expression of IFNA5 mRNA CTD PMID:17034753 NCBI chr 5:103,227,820...103,230,500 JBrowse link
G Lpl lipoprotein lipase decreases expression ISO beta Carotene results in decreased expression of LPL mRNA CTD PMID:21569430 NCBI chr16:25,596,205...25,621,928
Ensembl chr16:25,596,211...25,622,107
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
ISO
EXP
beta Carotene results in increased phosphorylation of MAPK1 protein
beta Carotene inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein]
CTD PMID:16206275 PMID:27154496 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
ISO
EXP
beta Carotene results in increased phosphorylation of MAPK3 protein
beta Carotene inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein]
CTD PMID:16206275 PMID:27154496 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
JBrowse link
G Mbl2 mannose binding lectin 2 multiple interactions ISO MBL2 gene polymorphism affects the susceptibility to [Vitamin A co-treated with beta Carotene] CTD PMID:16960176 NCBI chr 1:237,429,873...237,465,567
Ensembl chr 1:237,429,973...237,437,546
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member affects expression ISO beta Carotene affects the expression of MCL1 mRNA CTD PMID:17034753 NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:185,908,168...185,938,782
JBrowse link
G Meis2 Meis homeobox 2 increases expression ISO beta Carotene results in increased expression of MEIS2 mRNA CTD PMID:17034753 NCBI chr 3:102,742,904...102,944,833
Ensembl chr 3:123,197,066...123,397,751
JBrowse link
G Meox1 mesenchyme homeobox 1 increases expression ISO beta Carotene results in increased expression of MEOX1 mRNA CTD PMID:17034753 NCBI chr10:86,818,450...86,837,563
Ensembl chr10:87,318,695...87,337,976
JBrowse link
G Mettl21a methyltransferase 21A, HSPA lysine multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of METTL21A mRNA CTD PMID:24657404 NCBI chr 9:65,934,253...65,999,964
Ensembl chr 9:73,471,813...73,481,339
JBrowse link
G Mettl9 methyltransferase 9, His-X-His N1(pi)-histidine multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of METTL9 mRNA CTD PMID:24657404 NCBI chr 1:175,575,805...175,623,065
Ensembl chr 1:185,006,954...185,054,861
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase affects response to substance ISO MGMT gene SNP affects the susceptibility to beta Carotene CTD PMID:16014702 NCBI chr 1:201,140,832...201,367,481
Ensembl chr 1:201,140,661...201,367,482
JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions EXP [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of MKI67 mRNA CTD PMID:23859036 NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593
JBrowse link
G Mnx1 motor neuron and pancreas homeobox 1 increases expression ISO beta Carotene results in increased expression of MNX1 mRNA CTD PMID:17034753 NCBI chr 4:5,866,506...5,871,465
Ensembl chr 4:6,541,645...6,546,604
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP [Ascorbic Acid co-treated with beta Carotene co-treated with alpha-Tocopherol co-treated with Sodium Selenite] inhibits the reaction [Galactosamine results in increased activity of MPO protein] CTD PMID:31022331 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056
JBrowse link
G Mrpl57 mitochondrial ribosomal protein L57 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of MRPL57 mRNA CTD PMID:24657404 NCBI chr15:31,970,904...31,971,766
Ensembl chr15:36,086,457...36,087,298
JBrowse link
G Msh5 mutS homolog 5 increases expression ISO beta Carotene results in increased expression of MSH5 mRNA CTD PMID:17034753 NCBI chr20:3,773,867...3,793,337
Ensembl chr20:3,781,578...3,797,994
JBrowse link
G Mtch2 mitochondrial carrier 2 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of MTCH2 mRNA CTD PMID:24657404 NCBI chr 3:97,286,388...97,306,028
Ensembl chr 3:97,285,894...97,307,327
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming increases expression ISO beta Carotene results in increased expression of MUC5AC mRNA CTD PMID:17034753 NCBI chr 1:206,293,717...206,326,006
Ensembl chr 1:206,293,869...206,326,006
JBrowse link
G Nckap1 NCK-associated protein 1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of NCKAP1 mRNA CTD PMID:24657404 NCBI chr 3:85,824,333...85,898,748
Ensembl chr 3:85,824,336...85,898,797
JBrowse link
G Nom1 nucleolar protein with MIF4G domain 1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of NOM1 mRNA CTD PMID:24657404 NCBI chr 4:6,562,931...6,586,093
Ensembl chr 4:6,567,836...6,585,036
JBrowse link
G Nos1 nitric oxide synthase 1 increases expression ISO beta Carotene results in increased expression of NOS1 mRNA CTD PMID:17034753 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:44,287,614...44,371,837
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP [Ascorbic Acid co-treated with Vitamin E co-treated with beta Carotene co-treated with Copper] inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA] CTD PMID:18779489 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity
ISO beta Carotene promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]
beta Carotene results in increased activity of NR1I2 protein
CTD PMID:15949683 PMID:16632523 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:75,965,632...76,002,380
JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 increases expression ISO beta Carotene results in increased expression of OLR1 mRNA CTD PMID:17034753 NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:164,612,463...164,634,598
JBrowse link
G Pard6a par-6 family cell polarity regulator alpha multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of PARD6A mRNA CTD PMID:24657404 NCBI chr19:33,589,531...33,591,900
Ensembl chr19:50,499,442...50,502,674
JBrowse link
G Pcdh1 protocadherin 1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of PCDH1 mRNA CTD PMID:24657404 NCBI chr18:30,011,692...30,039,679
Ensembl chr18:30,258,154...30,290,436
JBrowse link
G Pcdhgc3 protocadherin gamma subfamily C, 3 increases expression ISO beta Carotene results in increased expression of PCDHGC3 mRNA CTD PMID:17034753 NCBI chr18:29,633,016...29,667,865 JBrowse link
G Pdgfrb platelet derived growth factor receptor beta multiple interactions EXP [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of PDGFRB mRNA; [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of PDGFRB protein CTD PMID:23859036 NCBI chr18:56,770,348...56,809,228
Ensembl chr18:56,770,348...56,809,233
JBrowse link
G Pik3r5 phosphoinositide-3-kinase, regulatory subunit 5 increases expression ISO beta Carotene results in increased expression of PIK3R5 protein CTD PMID:20025956 NCBI chr10:53,631,469...53,699,550
Ensembl chr10:53,631,476...53,699,539
JBrowse link
G Plat plasminogen activator, tissue type multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of PLAT mRNA CTD PMID:24657404 NCBI chr16:75,943,061...76,022,037
Ensembl chr16:75,943,064...75,967,696
JBrowse link
G Plscr1 phospholipid scramblase 1 increases expression ISO beta Carotene results in increased expression of PLSCR1 mRNA CTD PMID:17034753 NCBI chr 8:92,784,279...92,804,698
Ensembl chr 8:101,664,056...101,684,614
JBrowse link
G Plscr3 phospholipid scramblase 3 increases expression ISO beta Carotene results in increased expression of PLSCR3 mRNA CTD PMID:17034753 NCBI chr10:55,064,349...55,070,120
Ensembl chr10:55,065,345...55,070,369
JBrowse link
G Plscr4 phospholipid scramblase 4 increases expression ISO beta Carotene results in increased expression of PLSCR4 mRNA CTD PMID:17034753 NCBI chr 8:92,987,290...93,026,056
Ensembl chr 8:101,866,888...101,905,831
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression ISO beta Carotene results in decreased expression of PPARA mRNA CTD PMID:21569430 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression ISO beta Carotene results in decreased expression of PPARG mRNA CTD PMID:21569430 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
JBrowse link
G Rad51ap1 RAD51 associated protein 1 decreases expression ISO beta Carotene results in decreased expression of RAD51AP1 mRNA CTD PMID:17034753 NCBI chr 4:161,445,610...161,458,661
Ensembl chr 4:161,445,512...161,458,680
JBrowse link
G Rad51d RAD51 paralog D increases expression ISO beta Carotene results in increased expression of RAD51D mRNA CTD PMID:17034753 NCBI chr10:67,805,720...67,824,452
Ensembl chr10:68,238,273...68,321,902
JBrowse link
G Rara retinoic acid receptor, alpha decreases expression ISO beta Carotene results in decreased expression of RARA mRNA CTD PMID:17034753 NCBI chr10:84,379,780...84,424,371
Ensembl chr10:84,389,622...84,425,160
JBrowse link
G Rarb retinoic acid receptor, beta increases expression ISO beta Carotene results in increased expression of RARB mRNA CTD PMID:17034753 NCBI chr15:10,837,252...11,482,037
Ensembl chr15:11,131,358...11,482,040
JBrowse link
G Rarres1 retinoic acid receptor responder 1 increases expression ISO beta Carotene results in increased expression of RARRES1 mRNA CTD PMID:17034753 NCBI chr 2:154,059,761...154,094,021
Ensembl chr 2:154,059,761...154,094,024
JBrowse link
G Rbp4 retinol binding protein 4 multiple interactions ISO beta Carotene results in decreased expression of and results in decreased secretion of RBP4 protein CTD PMID:22542753 NCBI chr 1:245,306,349...245,313,551
Ensembl chr 1:245,306,349...245,313,898
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit decreases phosphorylation ISO beta Carotene results in decreased phosphorylation of RELA protein CTD PMID:26733226 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
G Rpp14 ribonuclease P/MRP subunit p14 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of RPP14 mRNA CTD PMID:24657404 NCBI chr15:16,837,796...16,847,970
Ensembl chr15:19,266,834...19,282,122
JBrowse link
G Rrm1 ribonucleotide reductase catalytic subunit M1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of RRM1 mRNA CTD PMID:24657404 NCBI chr 1:166,235,904...166,260,206
Ensembl chr 1:166,235,900...166,260,944
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO beta Carotene promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA] CTD PMID:16632523 NCBI chr 3:31,387,892...31,474,415
Ensembl chr 3:31,388,223...31,474,417
JBrowse link
G Scarb1 scavenger receptor class B, member 1 increases transport ISO SCARB1 protein results in increased transport of beta Carotene CTD PMID:16177187 NCBI chr12:36,957,302...37,023,982
Ensembl chr12:36,957,496...37,023,980
JBrowse link
G Six6 SIX homeobox 6 increases expression ISO beta Carotene results in increased expression of SIX6 mRNA CTD PMID:17034753 NCBI chr 6:91,634,568...91,639,548
Ensembl chr 6:97,370,435...97,375,415
JBrowse link
G Slc2a4 solute carrier family 2 member 4 decreases expression ISO beta Carotene results in decreased expression of SLC2A4 mRNA CTD PMID:21569430 NCBI chr10:55,164,721...55,170,289
Ensembl chr10:55,164,721...55,170,270
JBrowse link
G Sod1 superoxide dismutase 1 decreases expression ISO beta Carotene results in decreased expression of SOD1 mRNA CTD PMID:17034753 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of SOD2 mRNA; [Ascorbic Acid co-treated with Vitamin E co-treated with beta Carotene co-treated with Copper] inhibits the reaction [Streptozocin results in decreased expression of SOD2 mRNA]; [Ascorbic Acid co-treated with Vitamin E co-treated with beta Carotene co-treated with Copper] inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein] CTD PMID:18779489 PMID:23859036 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168
JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 affects expression ISO beta Carotene affects the expression of SPTLC2 mRNA CTD PMID:17034753 NCBI chr 6:106,948,682...107,031,532
Ensembl chr 6:112,679,623...112,762,640
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression ISO beta Carotene results in increased expression of SREBF1 mRNA CTD PMID:17034753 NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164
JBrowse link
G Tfcp2 transcription factor CP2 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TFCP2 mRNA CTD PMID:24657404 NCBI chr 7:131,616,777...131,658,995
Ensembl chr 7:133,495,577...133,537,531
JBrowse link
G Tgm2 transglutaminase 2 increases expression ISO beta Carotene results in increased expression of TGM2 mRNA CTD PMID:17034753 NCBI chr 3:167,192,612...167,221,845
Ensembl chr 3:167,192,612...167,304,240
JBrowse link
G Tgm4 transglutaminase 4 increases expression ISO beta Carotene results in increased expression of TGM4 mRNA CTD PMID:17034753 NCBI chr 8:122,689,429...122,726,463
Ensembl chr 8:131,566,887...131,603,920
JBrowse link
G Thoc7 THO complex subunit 7 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of THOC7 mRNA CTD PMID:24657404 NCBI chr15:11,262,362...11,277,200
Ensembl chr15:13,693,396...13,707,704
JBrowse link
G Tmem209 transmembrane protein 209 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TMEM209 mRNA CTD PMID:24657404 NCBI chr 4:59,102,943...59,128,636
Ensembl chr 4:60,069,060...60,105,946
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO beta Carotene affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]; beta Carotene promotes the reaction [Benzo(a)pyrene results in increased secretion of TNF protein]; pyrazolanthrone inhibits the reaction [beta Carotene promotes the reaction [Benzo(a)pyrene results in increased secretion of TNF protein]]; Quercetin affects the reaction [beta Carotene affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]]; Quercetin inhibits the reaction [beta Carotene promotes the reaction [Benzo(a)pyrene results in increased secretion of TNF protein]]
beta Carotene promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
CTD PMID:19135038 PMID:21447443 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 increases expression ISO beta Carotene results in increased expression of TNFRSF9 mRNA CTD PMID:17034753 NCBI chr 5:161,381,662...161,408,003
Ensembl chr 5:166,664,494...166,690,831
JBrowse link
G Tnfsf10 TNF superfamily member 10 increases expression ISO beta Carotene results in increased expression of TNFSF10 mRNA CTD PMID:17034753 NCBI chr 2:112,136,550...112,155,903 JBrowse link
G Ttc21b tetratricopeptide repeat domain 21B multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TTC21B mRNA CTD PMID:24657404 NCBI chr 3:71,269,425...71,343,936
Ensembl chr 3:71,269,425...71,343,936
JBrowse link
G Twf1 twinfilin actin-binding protein 1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TWF1 mRNA CTD PMID:24657404 NCBI chr 7:127,595,210...127,607,821
Ensembl chr 7:127,595,210...127,607,105
JBrowse link
G Txndc9 thioredoxin domain containing 9 increases expression ISO beta Carotene results in increased expression of TXNDC9 mRNA CTD PMID:17034753 NCBI chr 9:40,211,818...40,221,953
Ensembl chr 9:47,707,231...47,880,085
JBrowse link
G Tymp thymidine phosphorylase multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TYMP mRNA CTD PMID:24657404 NCBI chr 7:120,438,768...120,444,088
Ensembl chr 7:122,316,520...122,324,003
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO beta Carotene results in decreased expression of VEGFA mRNA CTD PMID:36819991 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
JBrowse link
G Xrcc3 X-ray repair cross complementing 3 increases expression ISO beta Carotene results in increased expression of XRCC3 mRNA CTD PMID:17034753 NCBI chr 6:136,684,558...136,694,822
Ensembl chr 6:136,684,558...136,694,822
JBrowse link
G Ythdc2 YTH N6-methyladenosine RNA binding protein C2 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of YTHDC2 mRNA CTD PMID:24657404 NCBI chr18:37,266,559...37,331,681
Ensembl chr18:37,517,248...37,582,550
JBrowse link
G Zdhhc3 zinc finger DHHC-type palmitoyltransferase 3 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ZDHHC3 mRNA CTD PMID:24657404 NCBI chr 8:122,725,206...122,773,542
Ensembl chr 8:131,602,663...131,650,998
JBrowse link
bixin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfe2l2 NFE2 like bZIP transcription factor 2 decreases ubiquitination ISO bixin results in decreased ubiquitination of NFE2L2 protein CTD PMID:30698894 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
JBrowse link
canthaxanthin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO
EXP
Canthaxanthin results in increased expression of CYP1A1 mRNA CTD PMID:9271336 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP
ISO
Canthaxanthin results in increased expression of CYP1A2 mRNA CTD PMID:9271336 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
JBrowse link
capsanthin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gja1 gap junction protein, alpha 1 multiple interactions EXP capsanthin inhibits the reaction [Hydrogen Peroxide results in decreased expression of GJA1 mRNA]; capsanthin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of GJA1 protein] CTD PMID:27154496 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP capsanthin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein] CTD PMID:27154496 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP capsanthin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein] CTD PMID:27154496 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
JBrowse link
carotenoid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bco2 beta-carotene oxygenase 2 decreases metabolic processing
multiple interactions
ISO BCO2 gene mutant form results in decreased metabolism of Carotenoids
[[BCO2 gene mutant form results in decreased metabolism of Carotenoids] which results in increased abundance of Carotenoids] which results in increased expression of SOD2 protein; [BCO2 gene mutant form results in decreased metabolism of Carotenoids] which results in increased abundance of Carotenoids; BCO2 protein results in increased oxidation of and results in increased cleavage of Carotenoids
CTD PMID:21106934 NCBI chr 8:50,882,174...50,907,676
Ensembl chr 8:59,778,575...59,799,168
JBrowse link
G Cat catalase increases activity ISO Carotenoids results in increased activity of CAT protein CTD PMID:29205955 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects response to substance ISO CYP1A2 protein polymorphism affects the susceptibility to Carotenoids CTD PMID:15095308 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
JBrowse link
G Nat1 N-acetyltransferase 1 affects response to substance ISO NAT1 protein polymorphism affects the susceptibility to Carotenoids CTD PMID:15095308 NCBI chr16:26,984,882...27,005,194
Ensembl chr16:26,982,625...26,986,527
JBrowse link
G Nat2 N-acetyltransferase 2 affects response to substance ISO NAT2 protein polymorphism affects the susceptibility to Carotenoids CTD PMID:15095308 NCBI chr16:26,974,874...27,005,191
Ensembl chr16:26,974,601...26,976,304
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression ISO Carotenoids results in decreased expression of PPARG mRNA CTD PMID:11237167 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
JBrowse link
G Rarg retinoic acid receptor, gamma increases expression ISO Carotenoids results in increased expression of RARG mRNA CTD PMID:11237167 NCBI chr 7:135,246,427...135,268,889
Ensembl chr 7:135,246,427...135,268,889
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression
ISO [[BCO2 gene mutant form results in decreased metabolism of Carotenoids] which results in increased abundance of Carotenoids] which results in increased expression of SOD2 protein
Carotenoids results in increased expression of SOD2 protein
CTD PMID:21106934 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168
JBrowse link
crocin-1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp5 acid phosphatase 5, tartrate resistant multiple interactions ISO crocin promotes the reaction [pyrazolanthrone inhibits the reaction [TNFSF11 protein results in increased activity of ACP5 protein]] CTD PMID:30580027 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:28,939,985...28,943,929
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP crocin inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 mRNA]; crocin inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein] CTD PMID:32633567 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503
JBrowse link
G Akt2 AKT serine/threonine kinase 2 multiple interactions ISO crocin inhibits the reaction [[TNFSF11 protein co-treated with pyrazolanthrone] results in increased expression of AKT2 mRNA] CTD PMID:30580027 NCBI chr 1:92,004,705...92,061,420
Ensembl chr 1:92,014,859...92,061,420
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions EXP crocin inhibits the reaction [Tartrazine results in increased activity of ALPL protein] CTD PMID:30657462 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:155,234,775...155,254,167
JBrowse link
G Atg5 autophagy related 5 multiple interactions EXP crocin inhibits the reaction [Blood Glucose results in increased expression of ATG5 protein]; crocin promotes the reaction [Quercetin inhibits the reaction [Blood Glucose results in increased expression of ATG5 protein]]; Quercetin promotes the reaction [crocin inhibits the reaction [Blood Glucose results in increased expression of ATG5 protein]] CTD PMID:33021114 NCBI chr20:49,380,835...49,471,826
Ensembl chr20:49,380,813...49,471,821
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor multiple interactions EXP crocin inhibits the reaction [Cisplatin results in decreased expression of BAMBI mRNA] CTD PMID:32259551 NCBI chr17:54,121,251...54,125,816
Ensembl chr17:58,816,442...58,821,247
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
EXP
ISO
crocin inhibits the reaction [Arsenic Trioxide results in increased expression of BAX mRNA]; crocin inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]; crocin inhibits the reaction [Diazinon results in increased expression of BAX mRNA]; crocin inhibits the reaction [Diazinon results in increased expression of BAX protein]; crocin inhibits the reaction [Malathion results in increased expression of BAX protein]
crocin inhibits the reaction [Zearalenone results in increased expression of BAX protein]
crocin results in increased expression of BAX mRNA
CTD PMID:23523949 PMID:26231423 PMID:27353299 PMID:32886819 PMID:32920515 More... NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
ISO
EXP
[crocin co-treated with Paraquat] results in decreased expression of BCL2 mRNA; crocin inhibits the reaction [Zearalenone results in decreased expression of BCL2 protein]
crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 mRNA]; crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]
crocin results in decreased expression of BCL2 mRNA
CTD PMID:26231423 PMID:31911963 PMID:32886819 PMID:32920515 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression EXP crocin results in increased expression of BDNF mRNA; crocin results in increased expression of BDNF protein CTD PMID:24401376 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657
JBrowse link
G Becn1 beclin 1 multiple interactions EXP crocin inhibits the reaction [Blood Glucose results in increased expression of BECN1 protein]; crocin inhibits the reaction [Blood Glucose results in increased phosphorylation of BECN1 protein]; crocin promotes the reaction [Quercetin inhibits the reaction [Blood Glucose results in increased expression of BECN1 protein]]; Quercetin promotes the reaction [crocin inhibits the reaction [Blood Glucose results in increased expression of BECN1 protein]] CTD PMID:33021114 NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO crocin results in decreased expression of BIRC5 mRNA CTD PMID:32886819 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
increases expression
increases cleavage
EXP
ISO
crocin affects the reaction [Ethanol results in increased expression of CASP3 mRNA]; crocin inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 mRNA]; crocin inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein]; crocin inhibits the reaction [Carbon Tetrachloride results in increased activity of CASP3 protein]; crocin inhibits the reaction [Diazinon results in increased activity of CASP3 protein]; crocin inhibits the reaction [Diazinon results in increased cleavage of CASP3 protein]; crocin inhibits the reaction [Diazinon results in increased expression of CASP3 protein modified form]; crocin inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; crocin inhibits the reaction [Ethanol results in increased activity of CASP3 protein]; crocin inhibits the reaction [Malathion results in increased cleavage of CASP3 protein]; crocin inhibits the reaction [Tartrazine results in increased expression of CASP3 protein]
crocin results in increased activity of CASP3 protein
crocin results in increased expression of CASP3 mRNA
crocin inhibits the reaction [Paraquat results in increased expression of CASP3 mRNA]
Acetylcysteine inhibits the reaction [crocin results in increased activity of CASP3 protein]; MIR34A mRNA inhibits the reaction [crocin results in increased activity of CASP3 protein]; MYCN protein inhibits the reaction [crocin results in increased cleavage of CASP3 protein]; PTPN4 protein affects the reaction [crocin results in increased activity of CASP3 protein]
CTD PMID:23523949 PMID:25637687 PMID:25899501 PMID:26807765 PMID:27353299 More... NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Casp8 caspase 8 increases activity ISO crocin results in increased activity of CASP8 protein CTD PMID:32886819 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:67,758,033...67,806,699
JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
EXP
ISO
crocin inhibits the reaction [Diazinon results in increased cleavage of CASP9 protein]; crocin inhibits the reaction [Malathion results in increased cleavage of CASP9 protein]
crocin results in increased activity of CASP9 protein
CTD PMID:27353299 PMID:32886819 PMID:35274200 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cat catalase multiple interactions
increases expression
increases activity
decreases activity
EXP
ISO
crocin inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein]; crocin inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein]; crocin inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; crocin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; crocin inhibits the reaction [Tartrazine results in decreased activity of CAT protein]; crocin inhibits the reaction [Tartrazine results in decreased expression of CAT protein]
crocin results in increased expression of CAT protein
crocin results in increased activity of CAT protein
crocin inhibits the reaction [Patulin results in increased activity of CAT protein]; crocin inhibits the reaction [Zearalenone results in increased activity of CAT protein]
crocin results in decreased activity of CAT protein
CTD PMID:23488790 PMID:25899501 PMID:26231423 PMID:26584762 PMID:29217164 More... NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO crocin results in decreased expression of CCND1 mRNA CTD PMID:32886819 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
JBrowse link
G Ckm creatine kinase, M-type multiple interactions EXP crocin inhibits the reaction [Diazinon results in increased activity of CKM protein] CTD PMID:23523949 NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:88,189,485...88,199,719
JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions EXP [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of Amino Acids]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of Pantothenic Acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of phenylpyruvic acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Allantoin]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Amino Acids]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Carnitine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Citric Acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatinine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of phenylacetylglycine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Succinic Acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Uric Acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Uridine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased secretion of IL1B protein] CTD PMID:24709313 NCBI chr 7:130,977,561...131,006,627
Ensembl chr 7:130,977,561...131,006,627
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP crocin results in increased expression of and results in increased phosphorylation of CREB1 protein CTD PMID:24401376 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339
JBrowse link
G Cycs cytochrome c, somatic multiple interactions EXP crocin inhibits the reaction [Diazinon affects the localization of CYCS protein] CTD PMID:23523949 NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816
Ensembl chr18:80,982,668...80,984,816
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
decreases activity
EXP crocin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 mRNA]; crocin inhibits the reaction [Carbon Tetrachloride results in increased activity of CYP2E1 protein]
crocin results in decreased activity of CYP2E1 protein
CTD PMID:25899501 PMID:32633567 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495
JBrowse link
G Foxp2 forkhead box P2 increases expression ISO crocin results in increased expression of FOXP2 protein CTD PMID:36988377 NCBI chr 4:44,099,848...44,677,700
Ensembl chr 4:44,099,959...44,677,696
JBrowse link
G Glo1 glyoxalase 1 multiple interactions ISO crocin inhibits the reaction [[TNFSF11 protein co-treated with Pyruvaldehyde] results in decreased activity of GLO1 protein] CTD PMID:30580027 NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,665,061...8,683,191
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 multiple interactions EXP crocin inhibits the reaction [Tartrazine results in increased activity of GOT2 protein] CTD PMID:30657462 NCBI chr19:9,180,428...9,206,113
Ensembl chr19:9,180,431...9,206,111
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP
ISO
crocin inhibits the reaction [Carbon Tetrachloride results in increased activity of GPT protein]; crocin inhibits the reaction [Cisplatin results in increased activity of GPT protein]; crocin inhibits the reaction [Tartrazine results in increased activity of GPT protein]
crocin inhibits the reaction [Zearalenone results in increased expression of GPT protein]
CTD PMID:26231423 PMID:30657462 PMID:32259551 PMID:32633567 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of HMOX1 protein] CTD PMID:32920515 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like multiple interactions EXP crocin inhibits the reaction [Ethanol results in increased expression of HSPA1L mRNA] CTD PMID:25637687 NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,853,331...3,876,877
JBrowse link
G Il10 interleukin 10 multiple interactions EXP crocin inhibits the reaction [Doxorubicin results in decreased expression of IL10 protein] CTD PMID:26807765 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased secretion of IL1B protein]; crocin inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; crocin inhibits the reaction [Doxorubicin results in increased expression of IL1B protein] CTD PMID:23488790 PMID:24709313 PMID:26807765 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression
EXP
ISO
crocin inhibits the reaction [Arsenic Trioxide results in increased expression of IL6 mRNA]; crocin inhibits the reaction [Arsenic Trioxide results in increased expression of IL6 protein]; crocin inhibits the reaction [Carbon Tetrachloride results in increased expression of IL6 mRNA]; crocin inhibits the reaction [Carbon Tetrachloride results in increased expression of IL6 protein]; crocin inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; crocin inhibits the reaction [Ethanol results in decreased expression of IL6 protein]; crocin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]
crocin results in decreased expression of IL6 mRNA
CTD PMID:23488790 PMID:25637687 PMID:25899501 PMID:29409856 PMID:32633567 More... NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Ins1 insulin 1 multiple interactions EXP crocin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein] CTD PMID:29409856 NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682
JBrowse link
G Jak2 Janus kinase 2 multiple interactions ISO crocin affects the expression of and affects the phosphorylation of JAK2 protein CTD PMID:32886819 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions EXP crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of KEAP1 protein] CTD PMID:32920515 NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:28,044,555...28,054,042
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions EXP crocin inhibits the reaction [Diazinon results in decreased expression of LDLR mRNA] CTD PMID:24132704 NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:28,546,146...28,570,675
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions EXP [Quercetin co-treated with crocin] inhibits the reaction [Blood Glucose results in increased lipidation of MAP1LC3B protein]; crocin inhibits the reaction [Blood Glucose results in increased lipidation of MAP1LC3B protein]; Quercetin promotes the reaction [crocin inhibits the reaction [Blood Glucose results in increased lipidation of MAP1LC3B protein]] CTD PMID:33021114 NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358
Ensembl chr16:66,574,407...66,584,358
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases phosphorylation
EXP
ISO
crocin inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK1 protein]; crocin inhibits the reaction [Diazinon results in decreased phosphorylation of MAPK1 protein]
crocin results in decreased phosphorylation of MAPK1 protein
CTD PMID:24132704 PMID:28689058 PMID:32886819 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
decreases phosphorylation
EXP
ISO
crocin inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK3 protein]; crocin inhibits the reaction [Diazinon results in decreased phosphorylation of MAPK3 protein]
crocin results in decreased phosphorylation of MAPK3 protein
crocin inhibits the reaction [[TNFSF11 protein co-treated with pyrazolanthrone] results in increased expression of MAPK3 mRNA]
CTD PMID:24132704 PMID:28689058 PMID:30580027 PMID:32886819 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
JBrowse link
G Mir122 microRNA 122 multiple interactions
decreases expression
EXP
ISO
crocin inhibits the reaction [bisphenol A results in increased expression of MIR122 mRNA]
crocin results in decreased expression of MIR122
CTD PMID:28689058 PMID:36988377 NCBI chr18:58,758,703...58,758,787 JBrowse link
G Mir29b1 microRNA 29b-1 increases expression
multiple interactions
EXP crocin results in increased expression of MIR29B1 mRNA
Cisplatin inhibits the reaction [crocin results in increased expression of MIR29B1 mRNA]; crocin inhibits the reaction [Cisplatin results in decreased expression of MIR29B1 mRNA]
CTD PMID:32259551 NCBI chr 4:59,650,987...59,651,067 JBrowse link
G Mir34a microRNA 34a multiple interactions ISO MIR34A mRNA inhibits the reaction [crocin results in increased activity of CASP3 protein]; MIR34A mRNA inhibits the reaction [crocin results in increased expression of PTPN4 protein] CTD PMID:35085590 NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:165,815,952...165,816,053
JBrowse link
G Mir9-1 microRNA 9-1 multiple interactions
increases expression
EXP Cisplatin inhibits the reaction [crocin results in increased expression of MIR9-1 mRNA]; crocin inhibits the reaction [Cisplatin results in decreased expression of MIR9-1 mRNA] CTD PMID:32259551 NCBI chr 2:173,677,139...173,677,227 JBrowse link
G Mpo myeloperoxidase multiple interactions EXP crocin inhibits the reaction [Ethanol results in increased activity of MPO protein] CTD PMID:25637687 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO crocin results in decreased expression of MYC mRNA CTD PMID:32886819 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor decreases response to substance
multiple interactions
decreases expression
ISO MYCN results in decreased susceptibility to crocin
crocin results in decreased expression of and results in decreased stability of MYCN mRNA; MYCN protein inhibits the reaction [crocin results in increased cleavage of CASP3 protein]; MYCN protein inhibits the reaction [crocin results in increased cleavage of PARP1 protein]
crocin results in decreased expression of MYCN protein
CTD PMID:30672053 NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:41,446,684...41,452,508
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions EXP crocin inhibits the reaction [Cisplatin results in increased expression of MYD88 mRNA]; crocin inhibits the reaction [Cisplatin results in increased expression of MYD88 protein] CTD PMID:32259551 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:127,952,161...127,956,230
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of NFE2L2 protein]; crocin inhibits the reaction [Cisplatin results in decreased expression of NFE2L2 protein] CTD PMID:32259551 PMID:32920515 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of NQO1 protein] CTD PMID:32920515 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
JBrowse link
G Ostm1 osteoclastogenesis associated transmembrane protein 1 multiple interactions ISO [crocin co-treated with pyrazolanthrone co-treated with TNFSF11 protein] results in decreased expression of OSTM1 mRNA; crocin inhibits the reaction [[TNFSF11 protein co-treated with pyrazolanthrone] results in increased expression of OSTM1 mRNA] CTD PMID:30580027 NCBI chr20:46,071,657...46,187,049
Ensembl chr20:47,653,670...47,769,237
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
ISO MYCN protein inhibits the reaction [crocin results in increased cleavage of PARP1 protein] CTD PMID:30672053 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions EXP crocin inhibits the reaction [Carbon Tetrachloride results in decreased expression of PPARG protein] CTD PMID:32633567 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
JBrowse link
G Prkab1 protein kinase AMP-activated non-catalytic subunit beta 1 multiple interactions EXP crocin promotes the reaction [Quercetin inhibits the reaction [Blood Glucose results in increased phosphorylation of PRKAB1 protein]]; Quercetin promotes the reaction [crocin inhibits the reaction [Blood Glucose results in increased phosphorylation of PRKAB1 protein]] CTD PMID:33021114 NCBI chr12:40,588,140...40,598,673
Ensembl chr12:46,249,010...46,259,482
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression
multiple interactions
ISO
EXP
crocin results in decreased expression of PTGS2 mRNA
crocin inhibits the reaction [Cyclophosphamide results in increased expression of PTGS2 protein]
CTD PMID:23488790 PMID:32886819 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
JBrowse link
G Ptpn4 protein tyrosine phosphatase, non-receptor type 4 multiple interactions
increases expression
ISO MIR34A mRNA inhibits the reaction [crocin results in increased expression of PTPN4 protein]; PTPN4 protein affects the reaction [crocin results in increased activity of CASP3 protein] CTD PMID:35085590 NCBI chr13:30,772,012...30,952,340
Ensembl chr13:33,324,808...33,504,957
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP crocin inhibits the reaction [Arsenic Trioxide results in increased expression of RELA protein]; crocin inhibits the reaction [Streptozocin results in increased expression of RELA protein] CTD PMID:29409856 PMID:32920515 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
G Smad2 SMAD family member 2 decreases expression
multiple interactions
EXP crocin results in decreased expression of SMAD2 protein
Cisplatin inhibits the reaction [crocin results in decreased expression of SMAD2 protein]; crocin inhibits the reaction [Cisplatin results in increased expression of SMAD2 protein]
CTD PMID:32259551 NCBI chr18:72,124,792...72,193,345
Ensembl chr18:72,124,863...72,187,388
JBrowse link
G Snca synuclein alpha multiple interactions EXP crocin inhibits the reaction [Malathion results in increased expression of SNCA mRNA]; crocin inhibits the reaction [Malathion results in increased expression of SNCA protein] CTD PMID:35274200 NCBI chr 4:91,026,474...91,127,444
Ensembl chr 4:91,026,474...91,126,315
JBrowse link
G Sod1 superoxide dismutase 1 increases expression
multiple interactions
EXP crocin results in increased expression of SOD1 protein
crocin inhibits the reaction [Tartrazine results in decreased expression of SOD1 protein]
CTD PMID:32870427 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399
JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 increases expression ISO crocin results in increased expression of SPRY2 protein CTD PMID:36988377 NCBI chr15:89,106,809...89,111,926
Ensembl chr15:89,103,731...89,115,074
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions EXP crocin inhibits the reaction [Blood Glucose results in decreased expression of SQSTM1 protein]; crocin promotes the reaction [Quercetin inhibits the reaction [Blood Glucose results in decreased expression of SQSTM1 protein]]; Quercetin promotes the reaction [crocin inhibits the reaction [Blood Glucose results in decreased expression of SQSTM1 protein]] CTD PMID:33021114 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:35,026,598...35,037,750
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO crocin affects the expression of and affects the phosphorylation of STAT3 protein CTD PMID:32886819 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP crocin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]; crocin inhibits the reaction [Blood Glucose results in increased expression of TGFB1 protein]; crocin inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA]; crocin inhibits the reaction [Cisplatin results in increased expression of TGFB1 protein]; crocin inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; crocin promotes the reaction [Quercetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]]; crocin promotes the reaction [Quercetin inhibits the reaction [Blood Glucose results in increased expression of TGFB1 protein]]; Quercetin promotes the reaction [crocin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]]; Quercetin promotes the reaction [crocin inhibits the reaction [Blood Glucose results in increased expression of TGFB1 protein]] CTD PMID:29409856 PMID:32259551 PMID:32633567 PMID:33021114 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 multiple interactions EXP crocin inhibits the reaction [Cisplatin results in increased expression of TGFBR1 protein] CTD PMID:32259551 NCBI chr 5:66,449,348...66,506,371
Ensembl chr 5:66,449,293...66,527,260
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions EXP crocin inhibits the reaction [Cisplatin results in increased expression of TLR4 mRNA]; crocin inhibits the reaction [Cisplatin results in increased expression of TLR4 protein]; crocin inhibits the reaction [Streptozocin results in increased expression of TLR4 protein] CTD PMID:29409856 PMID:32259551 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
EXP
ISO
crocin inhibits the reaction [Arsenic Trioxide results in increased expression of TNF mRNA]; crocin inhibits the reaction [Arsenic Trioxide results in increased expression of TNF protein]; crocin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF mRNA]; crocin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]; crocin inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; crocin inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; crocin inhibits the reaction [Ethanol results in decreased expression of TNF protein]
crocin results in decreased expression of TNF mRNA
CTD PMID:23488790 PMID:25637687 PMID:25899501 PMID:26807765 PMID:32633567 More... NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions ISO [crocin co-treated with pyrazolanthrone co-treated with TNFSF11 protein] results in decreased expression of OSTM1 mRNA; crocin inhibits the reaction [[TNFSF11 protein co-treated with pyrazolanthrone] results in increased expression of AKT2 mRNA]; crocin inhibits the reaction [[TNFSF11 protein co-treated with pyrazolanthrone] results in increased expression of MAPK3 mRNA]; crocin inhibits the reaction [[TNFSF11 protein co-treated with pyrazolanthrone] results in increased expression of OSTM1 mRNA]; crocin inhibits the reaction [[TNFSF11 protein co-treated with pyrazolanthrone] results in increased expression of TRAF6 mRNA]; crocin inhibits the reaction [[TNFSF11 protein co-treated with Pyruvaldehyde] results in decreased activity of GLO1 protein]; crocin promotes the reaction [pyrazolanthrone inhibits the reaction [TNFSF11 protein results in increased activity of ACP5 protein]] CTD PMID:30580027 NCBI chr15:60,083,008...60,114,479
Ensembl chr15:60,083,008...60,114,479
JBrowse link
G Tnnt2 troponin T2, cardiac type multiple interactions EXP crocin inhibits the reaction [Doxorubicin results in increased expression of TNNT2 protein] CTD PMID:26807765 NCBI chr13:47,267,325...47,285,390
Ensembl chr13:49,822,304...49,837,125
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO crocin inhibits the reaction [Paraquat results in increased expression of TRP53 mRNA]; crocin inhibits the reaction [Zearalenone results in increased expression of TRP53 protein] CTD PMID:26231423 PMID:31911963 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link
G Traf6 TNF receptor associated factor 6 multiple interactions ISO crocin inhibits the reaction [[TNFSF11 protein co-treated with pyrazolanthrone] results in increased expression of TRAF6 mRNA] CTD PMID:30580027 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:108,418,513...108,443,328
JBrowse link
G Vgf VGF nerve growth factor inducible increases expression EXP crocin results in increased expression of VGF protein CTD PMID:24401376 NCBI chr12:19,637,313...19,645,123
Ensembl chr12:25,273,333...25,282,703
JBrowse link
fucoxanthin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acox1 acyl-CoA oxidase 1 increases expression ISO fucoxanthin results in increased expression of ACOX1 mRNA CTD PMID:20519145 NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,905,083...101,930,136
JBrowse link
G Acta1 actin, alpha 1, skeletal muscle multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of ACTA1 mRNA] CTD PMID:33448797 NCBI chr19:51,883,709...51,886,735
Ensembl chr19:68,781,168...68,786,178
JBrowse link
G Adcy7 adenylate cyclase 7 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased methylation of ADCY7 gene]; fucoxanthin inhibits the reaction [Glucose results in increased expression of ADCY7 mRNA] CTD PMID:33448797 NCBI chr19:18,740,875...18,798,924
Ensembl chr19:34,914,322...34,936,743
JBrowse link
G Ak8 adenylate kinase 8 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of AK8 mRNA] CTD PMID:33448797 NCBI chr 3:12,028,895...12,144,468
Ensembl chr 3:32,426,421...32,542,431
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases expression
ISO fucoxanthin inhibits the reaction [Carrageenan results in increased phosphorylation of AKT1 protein]
fucoxanthin results in decreased expression of AKT1 mRNA
CTD PMID:26418808 PMID:35266250 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
JBrowse link
G Alcam activated leukocyte cell adhesion molecule multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of ALCAM mRNA] CTD PMID:33448797 NCBI chr11:48,336,123...48,536,296
Ensembl chr11:61,805,049...62,006,876
JBrowse link
G Ankrd61 ankyrin repeat domain 61 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of ANKRD61 mRNA] CTD PMID:33448797 NCBI chr12:10,718,908...10,723,267
Ensembl chr12:15,832,108...15,836,923
JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of ARHGDIB mRNA] CTD PMID:33448797 NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:171,554,140...171,573,068
JBrowse link
G Armcx6 armadillo repeat containing, X-linked 6 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of ARMCX6 mRNA] CTD PMID:33448797 NCBI chr  X:102,222,288...102,229,871
Ensembl chr  X:102,222,220...102,240,052
JBrowse link
G Atg10 autophagy related 10 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of ATG10 mRNA] CTD PMID:33448797 NCBI chr 2:22,109,304...22,398,313
Ensembl chr 2:23,844,482...24,133,368
JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of ATP2A1 mRNA] CTD PMID:33448797 NCBI chr 1:181,026,606...181,044,859
Ensembl chr 1:190,457,198...190,475,423
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of BAMBI mRNA] CTD PMID:33448797 NCBI chr17:54,121,251...54,125,816
Ensembl chr17:58,816,442...58,821,247
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO CDM-3008 inhibits the reaction [fucoxanthin inhibits the reaction [TNF protein results in increased expression of BAX protein]]; fucoxanthin inhibits the reaction [TNF protein results in increased expression of BAX protein] CTD PMID:39719254 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Bche butyrylcholinesterase multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of BCHE mRNA] CTD PMID:33448797 NCBI chr 2:160,607,289...160,699,760
Ensembl chr 2:160,606,288...160,699,760
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO fucoxanthin results in decreased expression of BCL2 mRNA; fucoxanthin results in decreased expression of BCL2 protein
CDM-3008 inhibits the reaction [fucoxanthin inhibits the reaction [TNF protein results in decreased expression of BCL2 protein]]; fucoxanthin inhibits the reaction [TNF protein results in decreased expression of BCL2 protein]
CTD PMID:35266250 PMID:38444163 PMID:39719254 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
decreases expression
ISO Acetylcysteine inhibits the reaction [fucoxanthin results in decreased expression of BCL2L1 protein]; BCL2L1 protein inhibits the reaction [fucoxanthin results in increased cleavage of PARP1 protein]; STAT3 protein inhibits the reaction [fucoxanthin results in decreased expression of BCL2L1 protein] CTD PMID:20594983 PMID:38444163 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO fucoxanthin results in decreased expression of BIRC5 protein CTD PMID:38444163 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155
JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
ISO fucoxanthin results in increased cleavage of CASP3 protein
Acetylcysteine inhibits the reaction [fucoxanthin results in increased cleavage of CASP3 protein]
CTD PMID:20594983 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Casp7 caspase 7 multiple interactions
increases cleavage
ISO Acetylcysteine inhibits the reaction [fucoxanthin results in increased cleavage of CASP7 protein] CTD PMID:20594983 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:265,442,676...265,482,512
JBrowse link
G Casz1 castor zinc finger 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of CASZ1 mRNA] CTD PMID:33448797 NCBI chr 5:159,243,965...159,393,935
Ensembl chr 5:164,527,112...164,677,014
JBrowse link
G Cat catalase multiple interactions ISO fucoxanthin inhibits the reaction [Carrageenan results in decreased activity of CAT protein] CTD PMID:26418808 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
JBrowse link
G Ccdc116 coiled-coil domain containing 116 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of CCDC116 mRNA] CTD PMID:33448797 NCBI chr11:83,842,707...83,850,607
Ensembl chr11:97,346,675...97,354,824
JBrowse link
G Ccr10 C-C motif chemokine receptor 10 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of CCR10 mRNA] CTD PMID:33448797 NCBI chr10:86,108,551...86,110,988
Ensembl chr10:86,608,836...86,611,273
JBrowse link
G Cd1d1 CD1d1 molecule multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of CD1D1 mRNA] CTD PMID:33448797 NCBI chr 2:174,721,522...174,725,029
Ensembl chr 2:174,721,522...174,725,029
JBrowse link
G Celsr1 cadherin, EGF LAG seven-pass G-type receptor 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of CELSR1 mRNA] CTD PMID:33448797 NCBI chr 7:118,867,450...119,004,859
Ensembl chr 7:118,867,450...119,004,856
JBrowse link
G Cemip cell migration inducing hyaluronidase 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of CEMIP mRNA] CTD PMID:33448797 NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:147,316,052...147,471,768
JBrowse link
G Cfp complement factor properdin multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of CFP mRNA] CTD PMID:33448797 NCBI chr  X:3,715,551...3,721,113
Ensembl chr  X:3,710,425...3,721,112
JBrowse link
G Cnn1 calponin 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of CNN1 mRNA] CTD PMID:33448797 NCBI chr 8:20,632,434...20,641,097
Ensembl chr 8:28,908,330...28,919,482
JBrowse link
G Col7a1 collagen type VII alpha 1 chain multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of COL7A1 mRNA] CTD PMID:33448797 NCBI chr 8:109,604,877...109,637,249
Ensembl chr 8:118,483,364...118,517,439
JBrowse link
G Cpq carboxypeptidase Q multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of CPQ mRNA] CTD PMID:33448797 NCBI chr 7:64,264,025...64,830,867
Ensembl chr 7:66,149,377...66,716,137
JBrowse link
G Crlf1 cytokine receptor-like factor 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of CRLF1 mRNA] CTD PMID:33448797 NCBI chr16:18,924,722...18,936,049
Ensembl chr16:18,957,956...18,969,970
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of CYP2E1 mRNA] CTD PMID:33448797 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495
JBrowse link
G Disp2 dispatched RND transporter family member 2 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of DISP2 mRNA] CTD PMID:33448797 NCBI chr 3:105,762,303...105,777,826
Ensembl chr 3:126,216,218...126,231,711
JBrowse link
G Dmtn dematin actin binding protein multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of DMTN mRNA] CTD PMID:33448797 NCBI chr15:52,087,667...52,111,956
Ensembl chr15:52,087,667...52,112,128
JBrowse link
G Drd3 dopamine receptor D3 increases activity ISO fucoxanthin results in increased activity of DRD3 protein CTD PMID:31323226 NCBI chr11:70,385,586...70,437,793
Ensembl chr11:70,385,586...70,446,760
JBrowse link
G Drd4 dopamine receptor D4 increases activity ISO fucoxanthin results in increased activity of DRD4 protein CTD PMID:31323226 NCBI chr 1:205,825,937...205,829,124
Ensembl chr 1:205,826,049...205,830,458
JBrowse link
G Dusp13b dual specificity phosphatase 13B multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of DUSP13B mRNA] CTD PMID:33448797 NCBI chr15:2,567,432...2,575,105
Ensembl chr15:2,609,049...2,624,887
JBrowse link
G Elapor1 endosome-lysosome associated apoptosis and autophagy regulator 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of ELAPOR1 mRNA] CTD PMID:33448797 NCBI chr 2:198,777,323...198,856,497
Ensembl chr 2:198,777,323...198,856,497
JBrowse link
G Esrp1 epithelial splicing regulatory protein 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of ESRP1 mRNA] CTD PMID:33448797 NCBI chr 5:24,427,611...24,482,157
Ensembl chr 5:29,225,360...29,279,278
JBrowse link
G Fam78b family with sequence similarity 78, member B multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of FAM78B mRNA] CTD PMID:33448797 NCBI chr13:79,162,393...79,250,958
Ensembl chr13:81,695,329...81,781,784
JBrowse link
G Fam83c family with sequence similarity 83, member C multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of FAM83C mRNA] CTD PMID:33448797 NCBI chr 3:144,333,736...144,339,758
Ensembl chr 3:164,793,105...164,799,995
JBrowse link
G Fam98c family with sequence similarity 98, member C multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of FAM98C mRNA] CTD PMID:33448797 NCBI chr 1:84,452,806...84,456,414
Ensembl chr 1:93,580,287...93,583,831
JBrowse link
G Fbp2 fructose-bisphosphatase 2 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of FBP2 mRNA] CTD PMID:33448797 NCBI chr17:2,236,088...2,253,702
Ensembl chr17:2,241,975...2,259,366
JBrowse link
G Fcho1 FCH and mu domain containing endocytic adaptor 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of FCHO1 mRNA] CTD PMID:33448797 NCBI chr16:18,447,424...18,464,738
Ensembl chr16:18,447,424...18,464,698
JBrowse link
G Fgf1 fibroblast growth factor 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of FGF1 mRNA] CTD PMID:33448797 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,939,870...30,961,393
JBrowse link
G Fgl2 fibrinogen-like 2 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of FGL2 mRNA] CTD PMID:33448797 NCBI chr 4:13,710,566...13,716,207
Ensembl chr 4:14,602,771...14,608,405
JBrowse link
G Flg filaggrin decreases expression ISO fucoxanthin results in decreased expression of FLG mRNA CTD PMID:27590588 NCBI chr 2:181,583,801...181,596,464
Ensembl chr 2:181,583,808...181,595,968
JBrowse link
G Gask1b golgi associated kinase 1B multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of GASK1B mRNA] CTD PMID:33448797 NCBI chr 2:165,047,689...165,112,479
Ensembl chr 2:167,345,809...167,410,603
JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression ISO fucoxanthin results in increased expression of GJA1 mRNA; fucoxanthin results in increased expression of GJA1 protein CTD PMID:19737546 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689
JBrowse link
G Gjb1 gap junction protein, beta 1 increases expression ISO fucoxanthin results in increased expression of GJB1 mRNA; fucoxanthin results in increased expression of GJB1 protein CTD PMID:19737546 NCBI chr  X:70,541,845...70,549,776
Ensembl chr  X:70,541,862...70,549,843
JBrowse link
G Gng2 G protein subunit gamma 2 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of GNG2 mRNA] CTD PMID:33448797 NCBI chr15:4,316,038...4,416,918
Ensembl chr15:4,365,135...4,466,059
JBrowse link
G Gpm6b glycoprotein m6b multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of GPM6B mRNA] CTD PMID:33448797 NCBI chr  X:31,689,485...31,836,199
Ensembl chr  X:31,690,359...31,733,272
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of GRIN1 mRNA] CTD PMID:33448797 NCBI chr 3:28,501,836...28,528,754
Ensembl chr 3:28,501,836...28,528,754
JBrowse link
G Gypc glycophorin C multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of GYPC mRNA] CTD PMID:33448797 NCBI chr18:24,434,921...24,467,592
Ensembl chr18:24,434,922...24,440,053
JBrowse link
G Hhat hedgehog acyltransferase multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of HHAT mRNA] CTD PMID:33448797 NCBI chr13:104,024,507...104,283,580
Ensembl chr13:106,541,866...106,811,563
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases activity ISO fucoxanthin results in decreased activity of HMGCR protein CTD PMID:20519145 NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:29,720,553...29,754,533
JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP
ISO
fucoxanthin results in increased expression of HMOX1 protein CTD PMID:23358145 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
JBrowse link
G Hunk hormonally upregulated Neu-associated kinase multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of HUNK mRNA] CTD PMID:33448797 NCBI chr11:29,641,122...29,758,392
Ensembl chr11:43,127,244...43,244,502
JBrowse link
G Ica1l islet cell autoantigen 1-like multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of ICA1L mRNA] CTD PMID:33448797 NCBI chr 9:61,410,959...61,469,884
Ensembl chr 9:68,906,148...68,963,692
JBrowse link
G Icam5 intercellular adhesion molecule 5 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of ICAM5 mRNA] CTD PMID:33448797 NCBI chr 8:27,843,563...27,851,767
Ensembl chr 8:27,844,780...27,857,104
JBrowse link
G Ifi44 interferon-induced protein 44 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of IFI44 mRNA] CTD PMID:33448797 NCBI chr 2:240,626,058...240,643,879
Ensembl chr 2:243,286,052...243,306,877
JBrowse link
G Il10 interleukin 10 multiple interactions ISO CDM-3008 inhibits the reaction [fucoxanthin inhibits the reaction [TNF protein results in decreased expression of IL10 mRNA]]; CDM-3008 inhibits the reaction [fucoxanthin inhibits the reaction [TNF protein results in decreased expression of IL10 protein]]; fucoxanthin inhibits the reaction [TNF protein results in decreased expression of IL10 mRNA]; fucoxanthin inhibits the reaction [TNF protein results in decreased expression of IL10 protein] CTD PMID:39719254 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; fucoxanthin inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL1B protein]
CDM-3008 inhibits the reaction [fucoxanthin inhibits the reaction [TNF protein results in increased expression of IL1B mRNA]]; CDM-3008 inhibits the reaction [fucoxanthin inhibits the reaction [TNF protein results in increased expression of IL1B protein]]; fucoxanthin inhibits the reaction [TNF protein results in increased expression of IL1B mRNA]; fucoxanthin inhibits the reaction [TNF protein results in increased expression of IL1B protein]
CTD PMID:22735499 PMID:35616142 PMID:39719254 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Il22 interleukin 22 multiple interactions ISO CDM-3008 inhibits the reaction [fucoxanthin inhibits the reaction [TNF protein results in decreased expression of IL22 mRNA]]; CDM-3008 inhibits the reaction [fucoxanthin inhibits the reaction [TNF protein results in decreased expression of IL22 protein]]; fucoxanthin inhibits the reaction [TNF protein results in decreased expression of IL22 mRNA]; fucoxanthin inhibits the reaction [TNF protein results in decreased expression of IL22 protein] CTD PMID:39719254 NCBI chr 7:53,801,206...53,805,673
Ensembl chr 7:55,686,896...55,692,201
JBrowse link
G Il23r interleukin 23 receptor multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of IL23R mRNA] CTD PMID:33448797 NCBI chr 4:97,910,230...98,003,759
Ensembl chr 4:97,909,972...98,004,110
JBrowse link
G Il24 interleukin 24 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of IL24 mRNA] CTD PMID:33448797 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:44,905,363...44,910,760
JBrowse link
G Il6 interleukin 6 multiple interactions ISO fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; fucoxanthin inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL6 protein]
CDM-3008 inhibits the reaction [fucoxanthin inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]]; CDM-3008 inhibits the reaction [fucoxanthin inhibits the reaction [TNF protein results in increased expression of IL6 protein]]; fucoxanthin inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]; fucoxanthin inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]; fucoxanthin inhibits the reaction [TNF protein results in increased expression of IL6 protein]
CTD PMID:22735499 PMID:35616142 PMID:38444163 PMID:39719254 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Irag1 inositol 1,4,5-triphosphate receptor associated 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of IRAG1 mRNA] CTD PMID:33448797 NCBI chr 1:164,981,716...165,094,232
Ensembl chr 1:174,416,385...174,528,851
JBrowse link
G Irf7 interferon regulatory factor 7 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of IRF7 mRNA] CTD PMID:33448797 NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:205,796,959...205,800,023
JBrowse link
G Jak2 Janus kinase 2 decreases phosphorylation
affects binding
multiple interactions
ISO fucoxanthin results in decreased phosphorylation of JAK2 protein
fucoxanthin binds to JAK2 protein
CDM-3008 inhibits the reaction [fucoxanthin inhibits the reaction [TNF protein results in increased phosphorylation of JAK2 protein]]; fucoxanthin inhibits the reaction [TNF protein results in increased phosphorylation of JAK2 protein]
fucoxanthin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of JAK2 protein]
CTD PMID:38444163 PMID:39719254 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762
JBrowse link
G Kap kidney androgen regulated protein multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of KAP mRNA] CTD PMID:33448797 NCBI chr 4:166,674,595...166,677,639
Ensembl chr 4:168,405,988...168,409,032
JBrowse link
G Kcnip2 potassium voltage-gated channel interacting protein 2 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of KCNIP2 mRNA]; fucoxanthin inhibits the reaction [Glucose results in increased methylation of KCNIP2 gene] CTD PMID:33448797 NCBI chr 1:254,590,172...254,614,437
Ensembl chr 1:254,590,175...254,613,898
JBrowse link
G Lpcat1 lysophosphatidylcholine acyltransferase 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of LPCAT1 mRNA] CTD PMID:33448797 NCBI chr 1:29,766,070...29,816,401
Ensembl chr 1:31,594,622...31,644,946
JBrowse link
G Lrrc61 leucine rich repeat containing 61 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of LRRC61 mRNA] CTD PMID:33448797 NCBI chr 4:77,503,882...77,523,909
Ensembl chr 4:78,833,857...78,868,931
JBrowse link
G Ltc4s leukotriene C4 synthase multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of LTC4S mRNA] CTD PMID:33448797 NCBI chr10:34,560,476...34,562,790
Ensembl chr10:35,061,437...35,063,768
JBrowse link
G Ly96 lymphocyte antigen 96 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of LY96 mRNA] CTD PMID:33448797 NCBI chr 5:2,582,233...2,612,357
Ensembl chr 5:7,365,557...7,395,816
JBrowse link
G Mak male germ cell-associated kinase multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of MAK mRNA] CTD PMID:33448797 NCBI chr17:23,889,417...23,936,857
Ensembl chr17:23,889,516...23,936,855
JBrowse link
G Mamdc2 MAM domain containing 2 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of MAMDC2 mRNA] CTD PMID:33448797 NCBI chr 1:220,863,959...221,016,493
Ensembl chr 1:230,290,499...230,442,711
JBrowse link
G Maoa monoamine oxidase A decreases activity ISO fucoxanthin results in decreased activity of MAOA protein CTD PMID:31323226 NCBI chr  X:8,615,239...8,681,372
Ensembl chr  X:8,615,239...8,682,631
JBrowse link
G Maob monoamine oxidase B decreases activity ISO fucoxanthin results in decreased activity of MAOB protein CTD PMID:31323226 NCBI chr  X:8,490,405...8,594,065
Ensembl chr  X:8,490,344...8,594,375
JBrowse link
G Map3k13 mitogen-activated protein kinase kinase kinase 13 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of MAP3K13 mRNA] CTD PMID:33448797 NCBI chr11:79,094,087...79,235,181
Ensembl chr11:92,601,738...92,739,663
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO fucoxanthin inhibits the reaction [Carrageenan results in increased phosphorylation of MAPK1 protein]; fucoxanthin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] CTD PMID:26418808 PMID:35616142 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO fucoxanthin inhibits the reaction [Carrageenan results in increased phosphorylation of MAPK3 protein]; fucoxanthin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] CTD PMID:26418808 PMID:35616142 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO fucoxanthin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:35616142 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO fucoxanthin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK9 protein] CTD PMID:35616142 NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression ISO fucoxanthin results in decreased expression of MCL1 protein CTD PMID:38444163 NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:185,908,168...185,938,782
JBrowse link
G Mfsd3 major facilitator superfamily domain containing 3 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of MFSD3 mRNA] CTD PMID:33448797 NCBI chr 7:108,419,644...108,423,469
Ensembl chr 7:110,302,018...110,304,112
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I multiple interactions
increases expression
ISO Mercury inhibits the reaction [fucoxanthin results in increased expression of COX1 mRNA] CTD PMID:39947444 NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
Ensembl chr MT:5,309...6,853
JBrowse link
G Mt-nd1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 multiple interactions
increases expression
ISO Mercury inhibits the reaction [fucoxanthin results in increased expression of ND1 mRNA] CTD PMID:39947444 NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
Ensembl chr MT:2,729...3,685
JBrowse link
G Mt-nd5 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 increases expression
multiple interactions
ISO fucoxanthin results in increased expression of ND5 mRNA
Mercury inhibits the reaction [fucoxanthin results in increased expression of ND5 mRNA]
CTD PMID:39947444 NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
Ensembl chr MT:11,721...13,553
JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases expression ISO fucoxanthin results in decreased expression of MTOR mRNA CTD PMID:35266250 NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435
JBrowse link
G Myo7b myosin VIIb multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of MYO7B mRNA] CTD PMID:33448797 NCBI chr18:23,588,307...23,669,841
Ensembl chr18:23,862,533...23,944,049
JBrowse link
G Nkd2 NKD inhibitor of WNT signaling pathway 2 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of NKD2 mRNA] CTD PMID:33448797 NCBI chr 1:31,268,856...31,299,390
Ensembl chr 1:31,272,519...31,299,387
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; fucoxanthin inhibits the reaction [Carrageenan results in increased expression of NOS2 protein]
CDM-3008 inhibits the reaction [fucoxanthin inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]]; CDM-3008 inhibits the reaction [fucoxanthin inhibits the reaction [TNF protein results in increased expression of NOS2 protein]]; fucoxanthin inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; fucoxanthin inhibits the reaction [TNF protein results in increased expression of NOS2 protein]
CTD PMID:22735499 PMID:26418808 PMID:39719254 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
JBrowse link
G Nrbp2 nuclear receptor binding protein 2 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of NRBP2 mRNA] CTD PMID:33448797 NCBI chr 7:107,798,642...107,805,225
Ensembl chr 7:109,679,330...109,685,588
JBrowse link
G Ntm neurotrimin multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of NTM mRNA] CTD PMID:33448797 NCBI chr 8:27,376,582...28,366,604
Ensembl chr 8:35,635,640...36,624,807
JBrowse link
G Nxpe4 neurexophilin and PC-esterase domain family member 4 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of NXPE4 mRNA] CTD PMID:33448797 NCBI chr 8:48,502,697...48,744,101
Ensembl chr 8:57,631,895...57,644,186
JBrowse link
G Oas3 2'-5'-oligoadenylate synthetase 3 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of OAS3 mRNA] CTD PMID:33448797 NCBI chr12:35,779,028...35,802,781
Ensembl chr12:41,439,643...41,464,420
JBrowse link
G Ocln occludin multiple interactions ISO fucoxanthin inhibits the reaction [Dextran Sulfate results in decreased expression of OCLN protein] CTD PMID:39719254 NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:33,391,303...33,430,411
JBrowse link
G Pacsin1 protein kinase C and casein kinase substrate in neurons 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of PACSIN1 mRNA] CTD PMID:33448797 NCBI chr20:5,718,134...5,768,064
Ensembl chr20:5,721,311...5,767,109
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
ISO BCL2L1 protein inhibits the reaction [fucoxanthin results in increased cleavage of PARP1 protein]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [fucoxanthin results in increased cleavage of PARP1 protein]; STAT3 protein inhibits the reaction [fucoxanthin results in increased cleavage of PARP1 protein] CTD PMID:38444163 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
JBrowse link
G Pcdh17 protocadherin 17 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of PCDH17 mRNA] CTD PMID:33448797 NCBI chr15:60,222,088...60,316,172
Ensembl chr15:66,633,142...66,722,105
JBrowse link
G Pip5k1b phosphatidylinositol-4-phosphate 5-kinase type 1 beta multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased methylation of PIP5K1B gene]; fucoxanthin inhibits the reaction [Glucose results in increased expression of PIP5K1B mRNA] CTD PMID:33448797 NCBI chr 1:221,907,220...222,183,672
Ensembl chr 1:231,340,606...231,496,812
JBrowse link
G Pitpnm3 PITPNM family member 3 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of PITPNM3 mRNA] CTD PMID:33448797 NCBI chr10:56,674,697...56,766,552
Ensembl chr10:57,175,721...57,265,291
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression ISO fucoxanthin results in increased expression of PPARA mRNA CTD PMID:20519145 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression ISO fucoxanthin results in decreased expression of PPARG mRNA CTD PMID:20519145 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
JBrowse link
G Psen2 presenilin 2 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of PSEN2 mRNA] CTD PMID:33448797 NCBI chr13:94,499,451...94,528,419
Ensembl chr13:94,499,928...94,525,116
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO fucoxanthin analog affects the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; fucoxanthin analog affects the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; fucoxanthin inhibits the reaction [Carrageenan results in increased expression of PTGS2 protein]
CDM-3008 inhibits the reaction [fucoxanthin inhibits the reaction [TNF protein results in increased expression of PTGS2 mRNA]]; CDM-3008 inhibits the reaction [fucoxanthin inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]]; fucoxanthin inhibits the reaction [TNF protein results in increased expression of PTGS2 mRNA]; fucoxanthin inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]
CTD PMID:22735499 PMID:26418808 PMID:39719254 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
JBrowse link
G Ptgs2os prostaglandin-endoperoxide synthase 2, opposite strand multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of PTGS2OS mRNA] CTD PMID:33448797 NCBI chr13:62,160,002...62,163,710 JBrowse link
G Rab40b Rab40b, member RAS oncogene family multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of RAB40B mRNA] CTD PMID:33448797 NCBI chr10:107,129,801...107,157,375
Ensembl chr10:107,129,801...107,157,457
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO fucoxanthin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein] CTD PMID:35616142 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
G Retn resistin decreases expression ISO fucoxanthin results in decreased expression of RETN protein CTD PMID:20519145 NCBI chr12:1,710,881...1,712,621
Ensembl chr12:6,508,801...6,511,116
JBrowse link
G Rhoa ras homolog family member A multiple interactions ISO fucoxanthin inhibits the reaction [Lipopolysaccharides results in increased activity of RHOA protein] CTD PMID:35616142 NCBI chr 8:117,870,548...117,904,303
Ensembl chr 8:117,870,270...117,904,302
JBrowse link
G Rimbp3 RIMS binding protein 3 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of RIMBP3 mRNA] CTD PMID:33448797 NCBI chr11:83,783,816...83,789,391
Ensembl chr11:97,273,234...97,303,170
JBrowse link
G Rtp4 receptor (chemosensory) transporter protein 4 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of RTP4 mRNA] CTD PMID:33448797 NCBI chr11:77,237,341...77,249,194
Ensembl chr11:90,741,992...90,753,851
JBrowse link
G Shc4 SHC adaptor protein 4 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of SHC4 mRNA] CTD PMID:33448797 NCBI chr 3:112,880,598...112,974,216
Ensembl chr 3:133,334,034...133,427,826
JBrowse link
G Slc16a5 solute carrier family 16 member 5 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of SLC16A5 mRNA] CTD PMID:33448797 NCBI chr10:101,206,371...101,220,300
Ensembl chr10:101,206,398...101,220,300
JBrowse link
G Slc18a2 solute carrier family 18 member A2 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of SLC18A2 mRNA] CTD PMID:33448797 NCBI chr 1:268,399,815...268,435,229
Ensembl chr 1:268,400,016...268,435,231
JBrowse link
G Slc6a18 solute carrier family 6 member 18 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of SLC6A18 mRNA] CTD PMID:33448797 NCBI chr 1:29,607,288...29,621,925
Ensembl chr 1:31,436,630...31,450,478
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions
decreases phosphorylation
ISO CDM-3008 inhibits the reaction [fucoxanthin inhibits the reaction [TNF protein results in increased phosphorylation of STAT3 protein]]; fucoxanthin inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]; fucoxanthin inhibits the reaction [TNF protein results in increased phosphorylation of STAT3 protein]; STAT3 protein inhibits the reaction [fucoxanthin results in decreased expression of BCL2L1 protein]; STAT3 protein inhibits the reaction [fucoxanthin results in increased cleavage of PARP1 protein]
fucoxanthin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of STAT3 protein]
fucoxanthin results in decreased phosphorylation of STAT3 protein
CTD PMID:38444163 PMID:39719254 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359
JBrowse link
G Strip2 striatin interacting protein 2 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of STRIP2 mRNA] CTD PMID:33448797 NCBI chr 4:58,536,034...58,578,279
Ensembl chr 4:59,503,481...59,545,739
JBrowse link
G Syn1 synapsin I multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of SYN1 mRNA] CTD PMID:33448797 NCBI chr  X:3,725,745...3,780,940
Ensembl chr  X:3,725,714...3,780,938
JBrowse link
G Synpo2l synaptopodin 2-like multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of SYNPO2L mRNA] CTD PMID:33448797 NCBI chr15:3,681,224...3,690,673
Ensembl chr15:3,681,104...3,690,673
JBrowse link
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of TGFB1I1 mRNA] CTD PMID:33448797 NCBI chr 1:182,828,553...182,835,465
Ensembl chr 1:192,258,598...192,265,903
JBrowse link
G Thsd7a thrombospondin type 1 domain containing 7A multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of THSD7A mRNA] CTD PMID:33448797 NCBI chr 4:40,461,124...40,899,345
Ensembl chr 4:41,426,275...41,865,723
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions ISO fucoxanthin inhibits the reaction [Dextran Sulfate results in decreased expression of TJP1 protein] CTD PMID:39719254 NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:128,260,330...128,505,158
JBrowse link
G Tmeff1 transmembrane protein with EGF-like and two follistatin-like domains 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of TMEFF1 mRNA]; fucoxanthin inhibits the reaction [Glucose results in increased methylation of TMEFF1 gene] CTD PMID:33448797 NCBI chr 5:62,910,740...62,996,494
Ensembl chr 5:67,706,269...67,792,021
JBrowse link
G Tmem229b transmembrane protein 229B multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of TMEM229B mRNA] CTD PMID:33448797 NCBI chr 6:97,771,645...97,819,582
Ensembl chr 6:103,508,342...103,552,647
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; fucoxanthin inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of TNF protein]
CDM-3008 inhibits the reaction [fucoxanthin inhibits the reaction [TNF protein results in decreased expression of BCL2 protein]]; CDM-3008 inhibits the reaction [fucoxanthin inhibits the reaction [TNF protein results in decreased expression of IL10 mRNA]]; CDM-3008 inhibits the reaction [fucoxanthin inhibits the reaction [TNF protein results in decreased expression of IL10 protein]]; CDM-3008 inhibits the reaction [fucoxanthin inhibits the reaction [TNF protein results in decreased expression of IL22 mRNA]]; CDM-3008 inhibits the reaction [fucoxanthin inhibits the reaction [TNF protein results in decreased expression of IL22 protein]]; CDM-3008 inhibits the reaction [fucoxanthin inhibits the reaction [TNF protein results in increased expression of BAX protein]]; CDM-3008 inhibits the reaction [fucoxanthin inhibits the reaction [TNF protein results in increased expression of IL1B mRNA]]; CDM-3008 inhibits the reaction [fucoxanthin inhibits the reaction [TNF protein results in increased expression of IL1B protein]]; CDM-3008 inhibits the reaction [fucoxanthin inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]]; CDM-3008 inhibits the reaction [fucoxanthin inhibits the reaction [TNF protein results in increased expression of IL6 protein]]; CDM-3008 inhibits the reaction [fucoxanthin inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]]; CDM-3008 inhibits the reaction [fucoxanthin inhibits the reaction [TNF protein results in increased expression of NOS2 protein]]; CDM-3008 inhibits the reaction [fucoxanthin inhibits the reaction [TNF protein results in increased expression of PTGS2 mRNA]]; CDM-3008 inhibits the reaction [fucoxanthin inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]]; CDM-3008 inhibits the reaction [fucoxanthin inhibits the reaction [TNF protein results in increased phosphorylation of JAK2 protein]]; CDM-3008 inhibits the reaction [fucoxanthin inhibits the reaction [TNF protein results in increased phosphorylation of STAT3 protein]]; fucoxanthin inhibits the reaction [TNF protein results in decreased expression of BCL2 protein]; fucoxanthin inhibits the reaction [TNF protein results in decreased expression of IL10 mRNA]; fucoxanthin inhibits the reaction [TNF protein results in decreased expression of IL10 protein]; fucoxanthin inhibits the reaction [TNF protein results in decreased expression of IL22 mRNA]; fucoxanthin inhibits the reaction [TNF protein results in decreased expression of IL22 protein]; fucoxanthin inhibits the reaction [TNF protein results in increased expression of BAX protein]; fucoxanthin inhibits the reaction [TNF protein results in increased expression of IL1B mRNA]; fucoxanthin inhibits the reaction [TNF protein results in increased expression of IL1B protein]; fucoxanthin inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]; fucoxanthin inhibits the reaction [TNF protein results in increased expression of IL6 protein]; fucoxanthin inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; fucoxanthin inhibits the reaction [TNF protein results in increased expression of NOS2 protein]; fucoxanthin inhibits the reaction [TNF protein results in increased expression of PTGS2 mRNA]; fucoxanthin inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]; fucoxanthin inhibits the reaction [TNF protein results in increased phosphorylation of JAK2 protein]; fucoxanthin inhibits the reaction [TNF protein results in increased phosphorylation of STAT3 protein]
CTD PMID:22735499 PMID:35616142 PMID:39719254 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tnfsf13 TNF superfamily member 13 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of TNFSF13 mRNA] CTD PMID:33448797 NCBI chr10:54,898,805...54,901,815
Ensembl chr10:54,898,805...54,901,815
JBrowse link
G Ttc21a tetratricopeptide repeat domain 21A multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of TTC21A mRNA] CTD PMID:33448797 NCBI chr 8:119,667,044...119,702,028
Ensembl chr 8:128,544,734...128,580,086
JBrowse link
G Wnt7b Wnt family member 7B multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of WNT7B mRNA] CTD PMID:33448797 NCBI chr 7:118,514,684...118,559,316
Ensembl chr 7:118,514,684...118,559,316
JBrowse link
G Zfp521 zinc finger protein 521 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of ZFP521 mRNA] CTD PMID:33448797 NCBI chr18:4,775,952...5,068,592
Ensembl chr18:5,056,236...5,343,054
JBrowse link
G Zfp566 zinc finger protein 566 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of ZFP566 mRNA] CTD PMID:33448797 NCBI chr 1:85,318,449...85,342,186
Ensembl chr 1:94,446,515...94,460,665
JBrowse link
G Zxdc ZXD family zinc finger C multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of ZXDA mRNA] CTD PMID:33448797 NCBI chr 4:122,882,389...122,914,486
Ensembl chr 4:124,439,573...124,471,683
JBrowse link
lutein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Als2 alsin Rho guanine nucleotide exchange factor ALS2 multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of ALS2 mRNA; [Cisplatin co-treated with Lutein] results in increased expression of ALS2 mRNA
Lutein results in decreased expression of ALS2 mRNA
CTD PMID:24865317 NCBI chr 9:60,613,182...60,686,394
Ensembl chr 9:68,107,528...68,179,660
JBrowse link
G Apc APC regulator of WNT signaling pathway multiple interactions ISO [Cisplatin co-treated with Lutein] results in increased expression of APC mRNA CTD PMID:24865317 NCBI chr18:26,138,382...26,196,021
Ensembl chr18:26,102,679...26,197,022
JBrowse link
G Aqr aquarius intron-binding spliceosomal factor decreases expression
multiple interactions
ISO Lutein results in decreased expression of AQR mRNA
[Cisplatin co-treated with Lutein] results in decreased expression of AQR mRNA
CTD PMID:24865317 NCBI chr 3:100,874,987...100,945,026
Ensembl chr 3:121,329,289...121,399,321
JBrowse link
G Atr ATR serine/threonine kinase multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of ATR mRNA
Lutein results in decreased expression of ATR mRNA
CTD PMID:24865317 NCBI chr 8:105,306,299...105,403,742
Ensembl chr 8:105,306,305...105,403,718
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Lutein results in increased expression of BAX protein CTD PMID:17455471 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Lutein results in decreased expression of BCL2 protein CTD PMID:17455471 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression ISO Lutein results in increased expression of BCL2L1 protein CTD PMID:10750663 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907
JBrowse link
G Bco2 beta-carotene oxygenase 2 increases metabolic processing
affects metabolic processing
multiple interactions
ISO BCO2 protein results in increased metabolism of Lutein
BCO2 protein affects the metabolism of Lutein
[BCO2 protein affects the metabolism of Lutein] which results in increased abundance of 3'-dehydrolutein; [BCO2 protein results in increased metabolism of Lutein] which results in increased chemical synthesis of apocarotenal metabolite
CTD PMID:21106934 NCBI chr 8:50,882,174...50,907,676
Ensembl chr 8:59,778,575...59,799,168
JBrowse link
G Cat catalase multiple interactions ISO Lutein inhibits the reaction [deoxynivalenol results in increased expression of CAT protein] CTD PMID:20347963 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Lutein results in decreased expression of CCND1 protein CTD PMID:17718427 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
JBrowse link
G Ccs copper chaperone for superoxide dismutase increases expression ISO Lutein results in increased expression of CCS mRNA CTD PMID:24865317 NCBI chr 1:202,113,792...202,134,931
Ensembl chr 1:211,542,701...211,564,260
JBrowse link
G Cfd complement factor D decreases expression
decreases secretion
ISO Lutein results in decreased expression of CFD mRNA
Lutein results in decreased secretion of CFD protein
CTD PMID:26504594 NCBI chr 7:10,463,773...10,465,496
Ensembl chr 7:10,463,775...10,465,572
JBrowse link
G Ckb creatine kinase B multiple interactions EXP Lutein inhibits the reaction [Isoproterenol results in increased activity of CKB protein] CTD PMID:34435724 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:136,549,844...136,553,478
JBrowse link
G Ctsb cathepsin B increases expression
multiple interactions
ISO Lutein results in increased expression of CTSB mRNA
Cisplatin inhibits the reaction [Lutein results in increased expression of CTSB mRNA]
CTD PMID:24865317 NCBI chr15:41,565,607...41,586,479
Ensembl chr15:41,565,611...41,586,478
JBrowse link
G Cyba cytochrome b-245 alpha chain multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of CYBA mRNA
Lutein results in decreased expression of CYBA mRNA
CTD PMID:24865317 NCBI chr19:67,396,143...67,404,214
Ensembl chr19:67,396,143...67,404,214
JBrowse link
G Des desmin multiple interactions EXP Lutein inhibits the reaction [Isoproterenol results in decreased expression of DES protein] CTD PMID:34435724 NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:84,298,447...84,307,347
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit decreases expression
multiple interactions
ISO Lutein results in decreased expression of ERCC2 mRNA
[Cisplatin co-treated with Lutein] results in decreased expression of ERCC2 mRNA
CTD PMID:24865317 NCBI chr 1:88,161,342...88,175,102
Ensembl chr 1:88,160,988...88,175,102
JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor decreases expression ISO Lutein results in decreased expression of ERCC6 mRNA CTD PMID:24865317 NCBI chr16:7,771,311...7,841,895
Ensembl chr16:7,771,581...7,841,895
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 decreases expression ISO Lutein results in decreased expression of FMO2 mRNA CTD PMID:24865317 NCBI chr13:75,221,149...75,244,377
Ensembl chr13:77,757,629...77,777,534
JBrowse link
G Gab1 GRB2-associated binding protein 1 decreases expression
multiple interactions
ISO Lutein results in decreased expression of GAB1 mRNA
[Cisplatin co-treated with Lutein] results in decreased expression of GAB1 mRNA
CTD PMID:24865317 NCBI chr19:27,131,262...27,239,236
Ensembl chr19:44,035,063...44,143,617
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
increases expression
ISO Cisplatin inhibits the reaction [Lutein results in increased expression of GPX1 mRNA]; Lutein inhibits the reaction [Lipopolysaccharides results in decreased expression of GPX1 mRNA] CTD PMID:22040935 PMID:24865317 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581
JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions ISO [Lutein co-treated with Cisplatin] results in increased expression of GPX2 mRNA CTD PMID:24865317 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:101,226,745...101,230,862
JBrowse link
G Gpx3 glutathione peroxidase 3 multiple interactions ISO [Cisplatin co-treated with Lutein] results in decreased expression of GPX3 mRNA CTD PMID:24865317 NCBI chr10:39,529,335...39,537,406
Ensembl chr10:39,529,448...39,537,405
JBrowse link
G Gsr glutathione-disulfide reductase increases expression
multiple interactions
ISO Lutein results in increased expression of GSR mRNA
[Cisplatin co-treated with Lutein] results in decreased expression of GSR mRNA
CTD PMID:24865317 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:65,185,574...65,228,394
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 multiple interactions ISO [Cisplatin co-treated with Lutein] results in decreased expression of GSTK1 mRNA CTD PMID:24865317 NCBI chr 4:71,118,979...71,123,298
Ensembl chr 4:72,085,531...72,089,927
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO arsenic trioxide promotes the reaction [Lutein results in increased expression of HMOX1 mRNA]; arsenic trioxide promotes the reaction [Lutein results in increased expression of HMOX1 protein]; Lutein promotes the reaction [arsenic trioxide results in increased expression of HMOX1 mRNA]; Lutein promotes the reaction [arsenic trioxide results in increased expression of HMOX1 protein]
Lutein results in increased expression of HMOX1 mRNA; Lutein results in increased expression of HMOX1 protein
CTD PMID:25815309 PMID:26187899 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of IDH1 mRNA
Lutein results in decreased expression of IDH1 mRNA
CTD PMID:24865317 NCBI chr 9:74,027,887...74,057,442
Ensembl chr 9:74,027,892...74,049,555
JBrowse link
G Ift172 intraflagellar transport 172 multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of IFT172 mRNA
Lutein results in decreased expression of IFT172 mRNA
CTD PMID:24865317 NCBI chr 6:30,801,841...30,841,239
Ensembl chr 6:30,801,918...30,840,830
JBrowse link
G Ins1 insulin 1 multiple interactions
decreases expression
EXP [Lutein co-treated with alpha-Tocopherol] results in decreased expression of INS1 protein; [Lutein co-treated with Ascorbic Acid] results in decreased expression of INS1 protein
Lutein results in decreased expression of INS1 protein
CTD PMID:12949374 NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682
JBrowse link
G Kif9 kinesin family member 9 multiple interactions
increases expression
ISO Lutein promotes the reaction [Cisplatin results in decreased expression of KIF9 mRNA]
Lutein results in increased expression of KIF9 mRNA
CTD PMID:24865317 NCBI chr 8:119,338,014...119,406,632
Ensembl chr 8:119,338,088...119,383,137
JBrowse link
G Mb myoglobin increases expression ISO Lutein results in increased expression of MB mRNA CTD PMID:24865317 NCBI chr 7:110,640,511...110,647,742
Ensembl chr 7:110,640,512...110,647,958
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 multiple interactions
increases expression
ISO arsenic trioxide promotes the reaction [Lutein results in increased expression of MGST1 mRNA]; Lutein promotes the reaction [arsenic trioxide results in increased expression of MGST1 mRNA] CTD PMID:25815309 PMID:26187899 NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:172,760,886...172,776,875
JBrowse link
G Miat myocardial infarction associated transcript multiple interactions EXP Lutein inhibits the reaction [Isoproterenol results in increased expression of MIAT] CTD PMID:34435724 NCBI chr12:44,414,620...44,429,852 JBrowse link
G Mir200a microRNA 200a multiple interactions EXP Lutein inhibits the reaction [Isoproterenol results in decreased expression of MIR200A mRNA] CTD PMID:34435724 NCBI chr 5:171,930,717...171,930,805 JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
increases expression
ISO
EXP
arsenic trioxide promotes the reaction [Lutein results in increased expression of NFE2L2 mRNA]; arsenic trioxide promotes the reaction [Lutein results in increased expression of NFE2L2 protein]; Lutein promotes the reaction [arsenic trioxide results in increased expression of NFE2L2 mRNA]; Lutein promotes the reaction [arsenic trioxide results in increased expression of NFE2L2 protein]; Lutein results in increased expression of and affects the localization of NFE2L2 protein
Lutein inhibits the reaction [Isoproterenol results in decreased expression of NFE2L2 protein]
Lutein results in increased expression of NFE2L2 mRNA; Lutein results in increased expression of NFE2L2 protein
CTD PMID:25815309 PMID:26187899 PMID:34435724 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
JBrowse link
G Ngb neuroglobin increases expression ISO Lutein results in increased expression of NGB mRNA CTD PMID:24865317 NCBI chr 6:106,744,378...106,749,830
Ensembl chr 6:112,475,332...112,480,786
JBrowse link
G Nox4 NADPH oxidase 4 multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of NOX4 mRNA
Lutein results in decreased expression of NOX4 mRNA
CTD PMID:24865317 NCBI chr 1:150,313,736...150,491,480
Ensembl chr 1:150,313,728...150,491,483
JBrowse link
G Noxo1 NADPH oxidase organizer 1 multiple interactions ISO [Cisplatin co-treated with Lutein] results in decreased expression of NOXO1 mRNA CTD PMID:24865317 NCBI chr10:13,723,253...13,726,008
Ensembl chr10:14,228,205...14,230,541
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases expression
ISO [Cisplatin co-treated with Lutein] results in increased expression of NQO1 mRNA; arsenic trioxide promotes the reaction [Lutein results in increased expression of NQO1 mRNA]; arsenic trioxide promotes the reaction [Lutein results in increased expression of NQO1 protein]; Lutein promotes the reaction [arsenic trioxide results in increased expression of NQO1 mRNA]; Lutein promotes the reaction [arsenic trioxide results in increased expression of NQO1 protein]
Lutein results in increased expression of NQO1 mRNA; Lutein results in increased expression of NQO1 protein
CTD PMID:24865317 PMID:25815309 PMID:26187899 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
JBrowse link
G Nudt15 nudix hydrolase 15 decreases expression
multiple interactions
ISO Lutein results in decreased expression of NUDT15 mRNA
[Cisplatin co-treated with Lutein] results in decreased expression of NUDT15 mRNA
CTD PMID:24865317 NCBI chr15:55,117,312...55,123,983 JBrowse link
G Nxn nucleoredoxin increases expression
multiple interactions
ISO Lutein results in increased expression of NXN mRNA
Lutein inhibits the reaction [Cisplatin results in increased expression of NXN mRNA]
CTD PMID:24865317 NCBI chr10:61,109,322...61,247,578
Ensembl chr10:61,607,568...61,745,807
JBrowse link
G Park7 Parkinsonism associated deglycase multiple interactions ISO [Cisplatin co-treated with Lutein] results in decreased expression of PARK7 mRNA CTD PMID:24865317 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:166,636,552...166,659,825
JBrowse link
G Ppp1r15b protein phosphatase 1, regulatory subunit 15B multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of PPP1R15B mRNA
Lutein results in decreased expression of PPP1R15B mRNA
CTD PMID:24865317 NCBI chr13:44,577,840...44,585,737
Ensembl chr13:47,129,967...47,137,798
JBrowse link
G Prdx4 peroxiredoxin 4 increases expression ISO Lutein results in increased expression of PRDX4 mRNA CTD PMID:24865317 NCBI chr  X:43,876,374...43,893,815
Ensembl chr  X:43,876,417...43,893,812
JBrowse link
G Prdx5 peroxiredoxin 5 decreases expression ISO Lutein results in decreased expression of PRDX5 mRNA CTD PMID:24865317 NCBI chr 1:213,529,042...213,532,787
Ensembl chr 1:213,529,035...213,533,020
JBrowse link
G Prdx6 peroxiredoxin 6 multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of PRDX6 mRNA
Lutein results in decreased expression of PRDX6 mRNA
CTD PMID:24865317 NCBI chr13:73,528,746...73,539,295
Ensembl chr13:76,061,554...76,072,657
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions ISO [Cisplatin co-treated with Lutein] results in decreased expression of PTGS1 mRNA CTD PMID:24865317 NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:39,981,415...40,002,990
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Lutein inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 protein] CTD PMID:20347963 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO Lutein inhibits the reaction [deoxynivalenol affects the localization of RELA protein]; Lutein inhibits the reaction [deoxynivalenol results in increased expression of RELA protein] CTD PMID:20347963 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of SCD1 mRNA
Lutein results in decreased expression of SCD1 mRNA
CTD PMID:24865317 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:253,218,970...253,231,785
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
increases expression
ISO Lutein inhibits the reaction [Lipopolysaccharides results in decreased expression of SOD1 mRNA]
Lutein results in increased expression of SOD1 mRNA
CTD PMID:22040935 PMID:24865317 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of SOD2 mRNA; Lutein inhibits the reaction [Lipopolysaccharides results in decreased expression of SOD2 mRNA]
Lutein results in decreased expression of SOD2 mRNA
CTD PMID:22040935 PMID:24865317 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168
JBrowse link
G Sod3 superoxide dismutase 3 multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of SOD3 mRNA
Lutein results in decreased expression of SOD3 mRNA
CTD PMID:24865317 NCBI chr14:62,822,865...62,828,602
Ensembl chr14:62,811,177...62,829,125
JBrowse link
G Srxn1 sulfiredoxin 1 multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of SRXN1 mRNA
Lutein results in decreased expression of SRXN1 mRNA
CTD PMID:24865317 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:161,059,931...161,088,765
JBrowse link
G Tnnt2 troponin T2, cardiac type multiple interactions EXP Lutein inhibits the reaction [Isoproterenol results in decreased expression of TNNT2 protein] CTD PMID:34435724 NCBI chr13:47,267,325...47,285,390
Ensembl chr13:49,822,304...49,837,125
JBrowse link
G Txn1 thioredoxin 1 multiple interactions EXP Lutein inhibits the reaction [Isoproterenol results in decreased expression of TXN protein] CTD PMID:34435724 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:77,507,321...77,520,307
JBrowse link
G Txnip thioredoxin interacting protein multiple interactions EXP Lutein inhibits the reaction [Isoproterenol results in increased expression of TXNIP protein] CTD PMID:34435724 NCBI chr 2:186,781,933...186,785,736
Ensembl chr 2:186,781,163...186,785,731
JBrowse link
G Txnrd1 thioredoxin reductase 1 decreases expression
multiple interactions
ISO Lutein results in decreased expression of TXNRD1 mRNA
[Cisplatin co-treated with Lutein] results in decreased expression of TXNRD1 mRNA
CTD PMID:24865317 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:22,719,317...22,739,817
JBrowse link
G Ucp3 uncoupling protein 3 increases expression ISO Lutein results in increased expression of UCP3 mRNA CTD PMID:24865317 NCBI chr 1:164,227,910...164,240,893
Ensembl chr 1:164,227,882...164,241,210
JBrowse link
G Vim vimentin increases expression ISO Lutein results in increased expression of VIM mRNA CTD PMID:24865317 NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746
JBrowse link
G Xirp1 xin actin-binding repeat containing 1 increases expression ISO Lutein results in increased expression of XIRP1 mRNA CTD PMID:24865317 NCBI chr 8:119,744,778...119,757,547
Ensembl chr 8:128,611,641...128,653,565
JBrowse link
lycopene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme multiple interactions EXP Lycopene inhibits the reaction [bisphenol A results in decreased activity of ACE protein] CTD PMID:32153214 NCBI chr10:91,410,129...91,430,246
Ensembl chr10:91,409,819...91,430,942
JBrowse link
G Ache acetylcholinesterase multiple interactions EXP Lycopene inhibits the reaction [manganese chloride results in increased activity of ACHE protein]; Lycopene inhibits the reaction [Sodium Glutamate results in increased activity of ACHE protein] CTD PMID:22192907 PMID:26900785 NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410
JBrowse link
G Add1 adducin 1 decreases expression ISO lycopene results in decreased expression of ADD1 mRNA CTD PMID:16886892 NCBI chr14:80,333,242...80,401,641
Ensembl chr14:80,333,244...80,391,732
JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions ISO lycopene inhibits the reaction [HMGB1 protein results in increased expression of AGER protein]; lycopene inhibits the reaction [Lipopolysaccharides results in increased expression of AGER protein] CTD PMID:22429818 NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,151,965...4,155,685
JBrowse link
G Ahr aryl hydrocarbon receptor decreases expression
multiple interactions
ISO lycopene results in decreased expression of AHR mRNA
[Lycopene co-treated with Atrazine] results in increased expression of AHR mRNA; Lycopene inhibits the reaction [Atrazine results in increased expression of AHR protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of AHR mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of AHR protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of and results in increased localization of AHR protein]
CTD PMID:16886892 PMID:34670089 PMID:36216167 PMID:36403809 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
JBrowse link
G Aif1 allograft inflammatory factor 1 multiple interactions ISO lycopene inhibits the reaction [Galactose results in increased expression of AIF1 protein] CTD PMID:28974442 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,652,243...3,657,339
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation ISO lycopene results in decreased phosphorylation of AKT1 protein CTD PMID:17337101 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
JBrowse link
G Alad aminolevulinate dehydratase multiple interactions ISO
EXP
lycopene inhibits the reaction [Zearalenone results in decreased activity of ALAD protein]
lycopene inhibits the reaction [Mercuric Chloride results in decreased activity of ALAD protein]
CTD PMID:17516994 PMID:25682699 NCBI chr 5:80,977,562...80,987,901
Ensembl chr 5:80,977,562...80,988,041
JBrowse link
G Andpro androgen regulated protein decreases expression EXP lycopene results in decreased expression of ANDPRO mRNA CTD PMID:15084515 NCBI chr 3:136,718,601...136,725,131
Ensembl chr 3:157,171,740...157,178,104
JBrowse link
G Aqp1 aquaporin 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of AQP1 mRNA] CTD PMID:33960999 NCBI chr 4:85,812,784...85,824,964
Ensembl chr 4:85,812,784...85,830,504
JBrowse link
G Aqp11 aquaporin 11 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of AQP11 mRNA] CTD PMID:33960999 NCBI chr 1:152,046,515...152,056,675
Ensembl chr 1:161,457,754...161,467,945
JBrowse link
G Aqp2 aquaporin 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of AQP2 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of AQP2 protein] CTD PMID:33960999 NCBI chr 7:132,590,286...132,595,321
Ensembl chr 7:132,590,225...132,595,319
JBrowse link
G Aqp4 aquaporin 4 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of AQP4 mRNA] CTD PMID:33960999 NCBI chr18:6,782,389...6,799,034
Ensembl chr18:6,782,389...6,799,098
JBrowse link
G Aqp6 aquaporin 6 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of AQP6 mRNA] CTD PMID:33960999 NCBI chr 7:130,732,216...130,735,149
Ensembl chr 7:132,611,065...132,614,049
JBrowse link
G Aqp7 aquaporin 7 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of AQP7 mRNA] CTD PMID:33960999 NCBI chr 5:60,968,495...60,982,618
Ensembl chr 5:60,967,558...60,982,618
JBrowse link
G Ar androgen receptor decreases expression ISO lycopene results in decreased expression of AR mRNA CTD PMID:16886892 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:67,135,317...67,304,467
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator increases expression
multiple interactions
ISO Lycopene results in increased expression of ARNT mRNA
[Diethylhexyl Phthalate co-treated with Lycopene] results in decreased expression of ARNT mRNA; Lycopene inhibits the reaction [Atrazine results in increased expression of ARNT mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of ARNT mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of ARNT protein]
CTD PMID:34670089 PMID:36216167 PMID:36403809 NCBI chr 2:185,686,703...185,745,546
Ensembl chr 2:185,680,683...185,745,546
JBrowse link
G Atf6 activating transcription factor 6 multiple interactions EXP Lycopene inhibits the reaction [Oxaliplatin results in increased expression of ATF6 mRNA] CTD PMID:32544411 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:85,462,840...85,640,033
JBrowse link
G Atg10 autophagy related 10 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG10 mRNA] CTD PMID:30360616 NCBI chr 2:22,109,304...22,398,313
Ensembl chr 2:23,844,482...24,133,368
JBrowse link
G Atg13 autophagy related 13 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of ATG13 mRNA] CTD PMID:30360616 NCBI chr 3:77,647,069...77,681,028
Ensembl chr 3:98,101,552...98,136,743
JBrowse link
G Atg14 autophagy related 14 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of ATG14 mRNA] CTD PMID:30360616 NCBI chr15:20,795,750...20,827,113
Ensembl chr15:23,275,457...23,306,815
JBrowse link
G Atg16l1 autophagy related 16-like 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG16L1 mRNA] CTD PMID:30360616 NCBI chr 9:95,869,839...95,905,354
Ensembl chr 9:95,869,865...95,905,357
JBrowse link
G Atg16l2 autophagy related 16-like 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of ATG16L2 mRNA] CTD PMID:30360616 NCBI chr 1:165,100,946...165,123,307
Ensembl chr 1:165,102,936...165,115,473
JBrowse link
G Atg2b autophagy related 2B multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of ATG2B mRNA] CTD PMID:30360616 NCBI chr 6:124,522,283...124,592,412
Ensembl chr 6:130,286,986...130,357,109
JBrowse link
G Atg3 autophagy related 3 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG3 mRNA] CTD PMID:30360616 NCBI chr11:69,130,948...69,159,280
Ensembl chr11:69,121,952...69,159,280
JBrowse link
G Atg4a autophagy related 4A, cysteine peptidase multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG4A mRNA] CTD PMID:30360616 NCBI chr  X:104,665,345...104,765,271
Ensembl chr  X:109,453,689...109,553,760
JBrowse link
G Atg4b autophagy related 4B, cysteine peptidase multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of ATG4B mRNA] CTD PMID:30360616 NCBI chr 9:94,282,417...94,314,109
Ensembl chr 9:101,726,782...101,761,622
JBrowse link
G Atg4c autophagy related 4C, cysteine peptidase multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG4C mRNA] CTD PMID:30360616 NCBI chr 5:113,867,218...113,935,534
Ensembl chr 5:118,982,918...119,052,695
JBrowse link
G Atg5 autophagy related 5 multiple interactions ISO
EXP
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG5 mRNA]
[Glucose co-treated with Lycopene] results in increased expression of ATG5 mRNA
CTD PMID:30360616 PMID:38444079 NCBI chr20:49,380,835...49,471,826
Ensembl chr20:49,380,813...49,471,821
JBrowse link
G Atg7 autophagy related 7 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of ATG7 mRNA] CTD PMID:30360616 NCBI chr 4:149,390,000...149,597,534
Ensembl chr 4:149,391,390...149,598,319
JBrowse link
G Atg9a autophagy related 9A multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of ATG9A mRNA] CTD PMID:30360616 NCBI chr 9:76,677,403...76,688,050
Ensembl chr 9:84,126,071...84,136,666
JBrowse link
G Atg9b autophagy related 9B multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of ATG9B mRNA] CTD PMID:30360616 NCBI chr 4:10,784,934...10,793,832
Ensembl chr 4:11,678,299...11,686,079
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine affects the expression of ATP1A1 mRNA]; Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1A1 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of ATP1A1 mRNA] CTD PMID:26476475 PMID:27112537 PMID:33960999 NCBI chr 2:191,709,311...191,737,414
Ensembl chr 2:191,709,311...191,737,425
JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1A2 mRNA] CTD PMID:27112537 PMID:33960999 NCBI chr13:87,261,964...87,286,911
Ensembl chr13:87,261,968...87,286,911
JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 multiple interactions ISO lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1A3 mRNA] CTD PMID:26476475 NCBI chr 1:89,700,645...89,729,782
Ensembl chr 1:89,700,649...89,729,825
JBrowse link
G Atp1a4 ATPase Na+/K+ transporting subunit alpha 4 multiple interactions ISO Lycopene inhibits the reaction [Atrazine affects the expression of ATP1A4 mRNA] CTD PMID:26476475 PMID:27112537 NCBI chr13:87,216,139...87,252,155
Ensembl chr13:87,216,139...87,251,724
JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1B1 mRNA] CTD PMID:27112537 PMID:33960999 NCBI chr13:79,319,708...79,340,226
Ensembl chr13:79,319,706...79,340,549
JBrowse link
G Atp1b2 ATPase Na+/K+ transporting subunit beta 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine affects the expression of ATP1B2 mRNA]; Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1B2 mRNA] CTD PMID:26476475 PMID:27112537 PMID:33960999 NCBI chr10:54,817,473...54,823,708
Ensembl chr10:54,817,476...54,823,708
JBrowse link
G Atp1b3 ATPase Na+/K+ transporting subunit beta 3 multiple interactions ISO lycopene inhibits the reaction [Atrazine affects the expression of ATP1B3 mRNA] CTD PMID:26476475 NCBI chr 8:105,789,824...105,821,151
Ensembl chr 8:65,253,361...65,254,304
Ensembl chr 8:65,253,361...65,254,304
JBrowse link
G Atp1b4 ATPase Na+/K+ transporting family member beta 4 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1B4 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of ATP1B4 mRNA] CTD PMID:26476475 PMID:33960999 NCBI chr  X:121,952,923...121,974,146
Ensembl chr  X:121,923,061...121,973,654
JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine affects the expression of ATP2A1 mRNA] CTD PMID:27112537 NCBI chr 1:181,026,606...181,044,859
Ensembl chr 1:190,457,198...190,475,423
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine affects the expression of ATP2A2 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of ATP2A2 mRNA] CTD PMID:27112537 PMID:33960999 NCBI chr12:39,733,519...39,782,942
Ensembl chr12:39,733,458...39,782,934
JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2A3 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of ATP2A3 mRNA] CTD PMID:26476475 PMID:27112537 PMID:33960999 NCBI chr10:57,581,742...57,612,758
Ensembl chr10:58,079,852...58,111,278
JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine affects the expression of ATP2B1 mRNA]; Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2B1 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of ATP2B1 mRNA] CTD PMID:26476475 PMID:27112537 PMID:33960999 NCBI chr 7:35,622,267...35,731,904
Ensembl chr 7:35,622,461...35,731,904
JBrowse link
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2B2 mRNA] CTD PMID:26476475 PMID:27112537 NCBI chr 4:148,450,207...148,763,653
Ensembl chr 4:148,450,207...148,696,239
JBrowse link
G Atp2b3 ATPase plasma membrane Ca2+ transporting 3 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2B3 mRNA] CTD PMID:26476475 PMID:27112537 NCBI chr  X:151,216,483...151,289,069
Ensembl chr  X:156,367,852...156,438,153
JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 multiple interactions ISO Lycopene inhibits the reaction [Atrazine affects the expression of ATP2B4 mRNA] CTD PMID:26476475 PMID:27112537 NCBI chr13:47,708,157...47,807,389
Ensembl chr13:47,711,121...47,758,876
JBrowse link
G Atp2c1 ATPase secretory pathway Ca2+ transporting 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2C1 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of ATP2C1 mRNA] CTD PMID:26476475 PMID:27112537 PMID:33960999 NCBI chr 8:106,034,777...106,155,854
Ensembl chr 8:114,913,415...115,038,826
JBrowse link
G Atp2c2 ATPase secretory pathway Ca2+ transporting 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine affects the expression of ATP2C2 mRNA]; Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2C2 mRNA] CTD PMID:26476475 PMID:27112537 PMID:33960999 NCBI chr19:64,662,729...64,719,998
Ensembl chr19:64,662,715...64,719,996
JBrowse link
G Bach1 BTB domain and CNC homolog 1 increases expression ISO lycopene results in increased expression of BACH1 mRNA CTD PMID:16886892 NCBI chr11:26,939,429...26,974,876
Ensembl chr11:40,425,664...40,461,277
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of BAK1 protein] CTD PMID:36583613 NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974
JBrowse link
G Bap1 BRCA1 associated deubiquitinase 1 increases expression ISO lycopene results in increased expression of BAP1 mRNA CTD PMID:16886892 NCBI chr16:6,453,126...6,461,952
Ensembl chr16:6,452,974...6,461,952
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
ISO
EXP
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of BAX mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of BAX protein]; Lycopene inhibits the reaction [Sodium Fluoride results in increased expression of BAX mRNA]
Lycopene results in increased expression of BAX mRNA
Lycopene inhibits the reaction [Benzo(a)pyrene results in increased expression of BAX mRNA]; Lycopene inhibits the reaction [Benzo(a)pyrene results in increased expression of BAX protein]; Lycopene inhibits the reaction [bisphenol A results in increased expression of BAX mRNA]; Lycopene inhibits the reaction [Sodium Fluoride results in increased expression of BAX mRNA]; Lycopene inhibits the reaction [Sodium Glutamate results in increased expression of BAX mRNA]
CTD PMID:26742427 PMID:26900785 PMID:27871895 PMID:31568845 PMID:32153214 More... NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Bche butyrylcholinesterase multiple interactions EXP Lycopene inhibits the reaction [Sodium Glutamate results in increased activity of BCHE protein] CTD PMID:26900785 NCBI chr 2:160,607,289...160,699,760
Ensembl chr 2:160,606,288...160,699,760
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
increases expression
EXP
ISO
[Glucose co-treated with Lycopene] results in increased expression of BCL2 mRNA; [S-allylcysteine co-treated with Lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in increased expression of BCL2 protein]; Lycopene inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in increased expression of BCL2 protein]; Lycopene inhibits the reaction [Benzo(a)pyrene results in decreased expression of BCL2 mRNA]; Lycopene inhibits the reaction [Benzo(a)pyrene results in decreased expression of BCL2 protein]; Lycopene inhibits the reaction [bisphenol A results in decreased expression of BCL2 mRNA]; Lycopene inhibits the reaction [Sodium Fluoride results in decreased expression of BCL2 mRNA]; Lycopene inhibits the reaction [Sodium Glutamate results in decreased expression of BCL2 mRNA]
Lycopene results in decreased expression of BCL2 mRNA
Lycopene results in increased expression of BCL2 mRNA
lycopene inhibits the reaction [Sodium Fluoride results in decreased expression of BCL2 mRNA]
CTD PMID:16030430 PMID:26742427 PMID:26900785 PMID:27871895 PMID:31568845 More... NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Bco1 beta-carotene oxygenase 1 multiple interactions ISO BCO1 affects the reaction [lycopene results in decreased abundance of Testosterone] CTD PMID:21935922 NCBI chr19:45,149,250...45,186,102
Ensembl chr19:62,058,089...62,094,917
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO
EXP
Lycopene inhibits the reaction [Galactose results in decreased expression of BDNF mRNA]; Lycopene inhibits the reaction [Galactose results in decreased expression of BDNF protein]
Lycopene inhibits the reaction [bisphenol A results in decreased expression of BDNF protein]; Lycopene inhibits the reaction [Oxaliplatin results in decreased expression of BDNF protein]
CTD PMID:28974442 PMID:32153214 PMID:32544411 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657
JBrowse link
G Becn1 beclin 1 multiple interactions ISO
EXP
Lycopene inhibits the reaction [Atrazine results in increased expression of BECN1 mRNA]
[Glucose co-treated with Lycopene] results in increased expression of BECN1 mRNA
CTD PMID:30360616 PMID:38444079 NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase decreases expression ISO lycopene results in decreased expression of BRAF protein CTD PMID:17337101 NCBI chr 4:69,329,772...69,476,931
Ensembl chr 4:69,342,813...69,476,931
JBrowse link
G C1qa complement C1q A chain decreases expression ISO lycopene results in decreased expression of C1QA mRNA CTD PMID:19555370 NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:154,417,087...154,427,732
JBrowse link
G C4b complement C4B decreases expression ISO lycopene results in decreased expression of C4B mRNA CTD PMID:19555370 NCBI chr20:4,201,979...4,216,292
Ensembl chr20:4,201,961...4,216,289
JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions EXP Lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in increased expression of CALCA protein] CTD PMID:33592256 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:178,312,638...178,317,529
JBrowse link
G Casp1 caspase 1 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CASP1 protein] CTD PMID:36610486 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:10,746,333...10,882,275
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
EXP
ISO
[Glucose co-treated with Lycopene] results in increased expression of CASP3 mRNA; [S-allylcysteine co-treated with Lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP3 protein]; Lycopene inhibits the reaction [Atrazine results in increased expression of CASP3 mRNA]; Lycopene inhibits the reaction [Benzo(a)pyrene results in increased cleavage of CASP3 protein]; Lycopene inhibits the reaction [bisphenol A results in increased activity of CASP3 protein]; Lycopene inhibits the reaction [Oxaliplatin results in increased expression of CASP3 protein]; Lycopene inhibits the reaction [Sodium Fluoride results in increased activity of CASP3 protein]; Lycopene inhibits the reaction [Sodium Fluoride results in increased expression of CASP3 mRNA]
Lycopene results in increased expression of CASP3 mRNA
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CASP3 protein]; Lycopene inhibits the reaction [Sodium Fluoride results in increased activity of CASP3 protein]; Lycopene inhibits the reaction [Sodium Fluoride results in increased expression of CASP3 mRNA]
CTD PMID:16030430 PMID:26742427 PMID:27102619 PMID:27871895 PMID:31568845 More... NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Casp8 caspase 8 multiple interactions
increases expression
decreases expression
EXP
ISO
[Glucose co-treated with Lycopene] results in increased expression of CASP8 mRNA; [S-allylcysteine co-treated with Lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein]; Lycopene inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein]
Lycopene results in increased expression of CASP8 mRNA
lycopene results in decreased expression of CASP8 mRNA
CTD PMID:16030430 PMID:16886892 PMID:26742427 PMID:38444079 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:67,758,033...67,806,699
JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
EXP
ISO
[Glucose co-treated with Lycopene] results in increased expression of CASP9 mRNA; Lycopene inhibits the reaction [Sodium Fluoride results in increased expression of CASP9 mRNA]
Lycopene results in increased expression of CASP9 mRNA
lycopene inhibits the reaction [Sodium Fluoride results in increased activity of CASP9 protein]; lycopene inhibits the reaction [Sodium Fluoride results in increased expression of CASP9 mRNA]
CTD PMID:26742427 PMID:27871895 PMID:38444079 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cat catalase multiple interactions
decreases expression
increases activity
increases expression
EXP
ISO
Lycopene affects the reaction [Doxorubicin affects the activity of CAT protein]; Lycopene inhibits the reaction [Atrazine results in decreased activity of CAT protein]; Lycopene inhibits the reaction [Benzo(a)pyrene results in decreased activity of CAT protein]; Lycopene inhibits the reaction [Cadmium Chloride results in increased activity of CAT protein]; Lycopene inhibits the reaction [Mercuric Chloride results in increased activity of CAT protein]; Lycopene inhibits the reaction [Oxaliplatin results in decreased activity of CAT protein]; Lycopene inhibits the reaction [Sodium Glutamate results in increased activity of CAT protein]; Lycopene inhibits the reaction [Sodium Glutamate results in increased expression of CAT mRNA]
Lycopene results in decreased expression of CAT mRNA
Lycopene affects the reaction [Atrazine affects the expression of CAT mRNA]; Lycopene inhibits the reaction [Acetaminophen results in increased activity of CAT protein]; Lycopene inhibits the reaction [Atrazine results in decreased activity of CAT protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CAT mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CAT protein]
lycopene results in increased activity of CAT protein
lycopene results in increased expression of CAT
CTD PMID:16325981 PMID:17516994 PMID:17873360 PMID:19450652 PMID:20074268 More... NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CCL4 mRNA] CTD PMID:36583613 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,950,289...68,965,722
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CCL5 mRNA] CTD PMID:36583613 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,738,651...68,824,884
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression
ISO
EXP
lycopene inhibits the reaction [Genistein results in increased expression of CCND1 protein]; lycopene inhibits the reaction [IGF1 protein results in increased expression of CCND1 protein]
lycopene results in decreased expression of CCND1 protein
lycopene inhibits the reaction [[Dietary Fats co-treated with Diethylnitrosamine] results in increased expression of CCND1 protein]
CTD PMID:16565789 PMID:17051425 PMID:17337101 PMID:19551842 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
JBrowse link
G Ccne1 cyclin E1 decreases expression
increases expression
ISO lycopene results in decreased expression of CCNE1 protein
lycopene results in increased expression of CCNE1 mRNA
CTD PMID:16886892 PMID:17337101 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:99,918,674...99,927,822
JBrowse link
G Ccs copper chaperone for superoxide dismutase increases expression
multiple interactions
EXP Lycopene results in increased expression of CCS mRNA
[Glucose co-treated with Lycopene] results in increased expression of CCS mRNA
CTD PMID:38444079 NCBI chr 1:202,113,792...202,134,931
Ensembl chr 1:211,542,701...211,564,260
JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO Lycopene inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of CDH1 protein] CTD PMID:36087924 NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565
JBrowse link
G Cdh2 cadherin 2 multiple interactions ISO [Lycopene co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of CDH2 protein; Lycopene inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of CDH2 protein] CTD PMID:36087924 NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO lycopene results in decreased expression of CDK1 protein CTD PMID:17337101 NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO lycopene results in decreased expression of CDK4 protein CTD PMID:17337101 NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163
JBrowse link
G Cdk5 cyclin-dependent kinase 5 decreases expression ISO lycopene results in decreased expression of CDK5 protein CTD PMID:17337101 NCBI chr 4:11,647,098...11,651,606
Ensembl chr 4:11,647,141...11,652,777
JBrowse link
G Cdk7 cyclin-dependent kinase 7 decreases expression ISO lycopene results in decreased expression of CDK7 protein CTD PMID:17337101 NCBI chr 2:33,574,623...33,599,485
Ensembl chr 2:33,574,623...33,599,485
JBrowse link
G Cdk9 cyclin-dependent kinase 9 decreases expression ISO lycopene results in decreased expression of CDK9 protein CTD PMID:17337101 NCBI chr 3:15,996,467...16,001,315
Ensembl chr 3:36,394,169...36,399,528
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO lycopene inhibits the reaction [IGF1 protein results in increased expression of CDKN1A protein] CTD PMID:16565789 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
JBrowse link
G Cgas cyclic GMP-AMP synthase multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CGAS mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CGAS protein] CTD PMID:36583613 NCBI chr 8:79,292,282...79,306,998
Ensembl chr 8:88,174,512...88,185,859
JBrowse link
G Chga chromogranin A increases expression ISO lycopene results in increased expression of CHGA mRNA CTD PMID:16886892 NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:127,460,854...127,472,237
JBrowse link
G Chgb chromogranin B decreases expression ISO lycopene results in decreased expression of CHGB mRNA CTD PMID:16886892 NCBI chr 3:120,043,824...120,057,169
Ensembl chr 3:140,495,951...140,510,054
JBrowse link
G Ckb creatine kinase B multiple interactions EXP Lycopene inhibits the reaction [Sodium Glutamate results in increased activity of CKB protein] CTD PMID:26900785 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:136,549,844...136,553,478
JBrowse link
G Cldn11 claudin 11 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of CLDN11 protein] CTD PMID:36087924 NCBI chr 2:112,207,745...112,221,050
Ensembl chr 2:114,136,234...114,149,539
JBrowse link
G Cldn5 claudin 5 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of CLDN5 protein]; Lycopene inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of CLDN5 protein] CTD PMID:36087924 NCBI chr11:95,717,172...95,718,598
Ensembl chr11:95,717,176...95,719,322
JBrowse link
G Crb1 crumbs cell polarity complex component 1 decreases expression ISO lycopene results in decreased expression of CRB1 mRNA CTD PMID:16886892 NCBI chr13:50,801,484...50,989,261
Ensembl chr13:53,352,932...53,540,019
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions
increases expression
EXP Lycopene inhibits the reaction [bisphenol A results in decreased expression of CREB1 protein]
Lycopene results in increased expression of CREB1 protein
CTD PMID:32153214 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CSF2 mRNA] CTD PMID:36583613 NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031
JBrowse link
G Ctnnb1 catenin beta 1 increases expression
multiple interactions
ISO Lycopene results in increased expression of CTNNB1 protein
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of CTNNB1 protein]; Lycopene inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of CTNNB1 protein]
CTD PMID:36087924 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662
JBrowse link
G Ctss cathepsin S decreases expression ISO lycopene results in decreased expression of CTSS mRNA CTD PMID:19555370 NCBI chr 2:185,775,316...185,803,440
Ensembl chr 2:185,775,296...185,803,440
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CXCL10 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CXCL10 protein] CTD PMID:36583613 NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261
JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 decreases expression ISO lycopene results in decreased expression of CXCL14 mRNA CTD PMID:19555370 NCBI chr17:8,323,150...8,331,176
Ensembl chr17:8,323,143...8,331,172
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CXCL2 mRNA] CTD PMID:36583613 NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255
JBrowse link
G Cyb5a cytochrome b5 type A multiple interactions ISO lycopene inhibits the reaction [Atrazine results in increased expression of CYB5A protein] CTD PMID:26775023 NCBI chr18:78,213,067...78,245,677
Ensembl chr18:14,453,966...14,455,094
Ensembl chr18:14,453,966...14,455,094
JBrowse link
G Cygb cytoglobin increases expression EXP Lycopene results in increased expression of CYGB mRNA CTD PMID:38444079 NCBI chr10:101,877,675...101,887,442
Ensembl chr10:102,376,507...102,386,272
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions EXP lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of CYP11A1 protein] CTD PMID:19071209 NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity
multiple interactions
ISO lycopene results in decreased activity of CYP1A1 protein
Lycopene inhibits the reaction [Atrazine results in increased expression of CYP1A1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP1A1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP1A1 protein]
CTD PMID:19329757 PMID:26775023 PMID:34670089 PMID:36216167 PMID:36403809 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases expression
ISO [Lycopene co-treated with Atrazine] results in increased expression of CYP1A2 mRNA; Lycopene inhibits the reaction [Atrazine results in increased expression of CYP1A2 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP1A2 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP1A2 protein]
Lycopene results in increased expression of CYP1A2 mRNA
CTD PMID:26775023 PMID:34670089 PMID:36216167 PMID:36403809 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity
increases expression
multiple interactions
ISO lycopene results in decreased activity of CYP1B1 protein
Lycopene results in increased expression of CYP1B1 mRNA
[Lycopene co-treated with Atrazine] results in increased expression of CYP1B1 mRNA; Lycopene affects the reaction [Atrazine results in increased expression of CYP1B1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP1B1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP1B1 protein]
CTD PMID:19329757 PMID:26775023 PMID:34670089 PMID:36216167 PMID:36403809 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142
JBrowse link
G Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 decreases expression EXP Lycopene results in decreased expression of CYP21A1 mRNA CTD PMID:15084515 NCBI chr20:4,020,217...4,026,923
Ensembl chr20:4,028,391...4,031,543
JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 multiple interactions ISO Lycopene affects the reaction [Atrazine affects the expression of CYP2A4 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of CYP2A4 mRNA] CTD PMID:26775023 PMID:36216167 NCBI chr 1:91,299,584...91,307,650
Ensembl chr 1:91,299,561...91,307,649
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO Lycopene promotes the reaction [Atrazine results in increased expression of CYP2B10 mRNA] CTD PMID:36216167 NCBI chr 1:90,780,468...90,859,852 JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 multiple interactions ISO Lycopene affects the reaction [Atrazine results in increased expression of CYP2C29 mRNA] CTD PMID:36216167 NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of CYP2E1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP2E1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP2E1 protein] CTD PMID:26775023 PMID:36216167 PMID:36403809 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495
JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of CYP2F2 mRNA] CTD PMID:36216167 NCBI chr 1:82,416,107...82,429,897
Ensembl chr 1:91,543,768...91,557,553
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases activity ISO Lycopene results in increased activity of CYP3A4 protein CTD PMID:16632523 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of CYP3A13 mRNA] CTD PMID:36216167 NCBI chr12:21,919,955...21,960,160
Ensembl chr12:21,919,940...21,960,154
JBrowse link
G Cyp4v3 cytochrome P450, family 4, subfamily v, polypeptide 3 multiple interactions
increases expression
ISO Lycopene inhibits the reaction [Atrazine results in increased expression of CYP4V3 mRNA]
Lycopene results in increased expression of CYP4V3 mRNA
CTD PMID:36216167 NCBI chr16:46,917,929...46,958,735
Ensembl chr16:53,650,569...53,676,746
JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 multiple interactions ISO lycopene inhibits the reaction [Atrazine results in increased expression of CYP7B1 mRNA] CTD PMID:26775023 NCBI chr 2:102,419,011...102,586,047
Ensembl chr 2:102,419,011...102,451,804
JBrowse link
G Ddb2 damage specific DNA binding protein 2 increases expression ISO lycopene results in increased expression of DDB2 mRNA CTD PMID:16886892 NCBI chr 3:77,185,114...77,207,650
Ensembl chr 3:97,640,579...97,664,066
JBrowse link
G Dnm1l dynamin 1-like multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of DNM1L mRNA] CTD PMID:33908429 NCBI chr11:98,084,049...98,135,663
Ensembl chr11:98,085,397...98,137,420
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions EXP Lycopene inhibits the reaction [Oxaliplatin results in increased expression of EIF2AK3 mRNA] CTD PMID:32544411 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:104,363,833...104,425,268
JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4 gamma 1 increases expression ISO lycopene results in increased expression of EIF4G1 mRNA CTD PMID:16886892 NCBI chr11:80,221,919...80,241,958
Ensembl chr11:93,726,322...93,746,367
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions EXP Lycopene inhibits the reaction [Oxaliplatin results in increased expression of ERN1 mRNA] CTD PMID:32544411 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,830,428...91,920,791
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
increases expression
ISO lycopene inhibits the reaction [Estradiol results in increased activity of ESR1 protein]
lycopene results in increased expression of ESR1 mRNA
CTD PMID:16886892 PMID:17051425 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO lycopene inhibits the reaction [Estradiol results in increased activity of ESR2 protein] CTD PMID:17051425 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709
JBrowse link
G Fancc FA complementation group C decreases expression ISO lycopene results in decreased expression of FANCC mRNA CTD PMID:16886892 NCBI chr17:1,686,374...1,818,672
Ensembl chr17:1,687,017...1,835,096
JBrowse link
G Fancf FA complementation group F decreases expression ISO lycopene results in decreased expression of FANCF mRNA CTD PMID:16886892 NCBI chr 1:101,449,120...101,451,936
Ensembl chr 1:110,576,389...110,587,863
JBrowse link
G Faslg Fas ligand decreases expression ISO lycopene results in decreased expression of FASLG mRNA CTD PMID:16886892 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO lycopene results in increased expression of FOS mRNA CTD PMID:16886892 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of GCLC mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GCLC mRNA] CTD PMID:35917956 PMID:36216167 PMID:36610486 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression
multiple interactions
ISO Lycopene results in increased expression of GCLM protein
Lycopene inhibits the reaction [Atrazine results in increased expression of GCLM mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GCLM mRNA]
CTD PMID:35917956 PMID:36216167 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:213,031,838...213,055,003
JBrowse link
G Get1 guided entry of tail-anchored proteins factor 1 decreases expression ISO Lycopene results in decreased expression of GET1 mRNA CTD PMID:16886892 NCBI chr11:35,438,555...35,460,156
Ensembl chr11:48,915,289...48,929,416
JBrowse link
G Gfap glial fibrillary acidic protein decreases expression
multiple interactions
ISO
EXP
lycopene results in decreased expression of GFAP mRNA
Lycopene inhibits the reaction [Oxaliplatin results in increased expression of GFAP protein]
CTD PMID:19555370 PMID:32544411 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:88,352,986...88,361,685
JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression
multiple interactions
decreases phosphorylation
ISO
EXP
Lycopene results in increased expression of GJA1 protein
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of and results in increased phosphorylation of GJA1 protein]; Lycopene inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of and results in increased phosphorylation of GJA1 protein]; Lycopene results in increased expression of and results in decreased phosphorylation of GJA1 protein
Lycopene results in decreased phosphorylation of GJA1 protein
Lycopene inhibits the reaction [Benzo(a)pyrene results in decreased expression of GJA1 protein]
CTD PMID:16091010 PMID:31568845 PMID:36087924 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689
JBrowse link
G Gja4 gap junction protein, alpha 4 decreases expression ISO lycopene results in decreased expression of GJA4 mRNA CTD PMID:16886892 NCBI chr 5:139,633,324...139,635,857
Ensembl chr 5:144,914,147...144,921,216
JBrowse link
G Gja5 gap junction protein, alpha 5 decreases expression
increases expression
ISO lycopene results in decreased expression of GJA5 mRNA
lycopene results in increased expression of GJA5 mRNA
CTD PMID:16886892 NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:187,234,674...187,318,512
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
increases expression
ISO
EXP
Lycopene inhibits the reaction [Atrazine results in increased expression of GPX1 mRNA]
Lycopene results in increased expression of GPX1 mRNA
[Glucose co-treated with Lycopene] results in increased expression of GPX1 mRNA
CTD PMID:36216167 PMID:38444079 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581
JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of GPX2 mRNA] CTD PMID:36216167 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:101,226,745...101,230,862
JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression
multiple interactions
ISO Lycopene results in increased expression of GPX3 mRNA
Lycopene affects the reaction [Atrazine affects the expression of GPX3 mRNA]
CTD PMID:36216167 NCBI chr10:39,529,335...39,537,406
Ensembl chr10:39,529,448...39,537,405
JBrowse link
G Gpx4 glutathione peroxidase 4 decreases expression
multiple interactions
ISO lycopene results in decreased expression of GPX4 mRNA
Lycopene affects the reaction [Atrazine affects the expression of GPX4 mRNA]
CTD PMID:16886892 PMID:36216167 NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:10,300,832...10,303,629
JBrowse link
G Gpx5 glutathione peroxidase 5 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of GPX5 mRNA] CTD PMID:36216167 NCBI chr17:43,436,126...43,443,074
Ensembl chr17:48,093,895...48,138,801
JBrowse link
G Gpx6 glutathione peroxidase 6 increases expression ISO Lycopene results in increased expression of GPX6 mRNA CTD PMID:36216167 NCBI chr17:43,408,472...43,416,091
Ensembl chr17:48,104,197...48,111,007
JBrowse link
G Gpx7 glutathione peroxidase 7 increases expression
multiple interactions
ISO Lycopene results in increased expression of GPX7 mRNA
Lycopene inhibits the reaction [Atrazine results in increased expression of GPX7 mRNA]
CTD PMID:36216167 NCBI chr 5:123,145,151...123,153,141
Ensembl chr 5:128,372,875...128,381,725
JBrowse link
G Gpx8 glutathione peroxidase 8 increases expression
multiple interactions
ISO Lycopene results in increased expression of GPX8 mRNA
Lycopene inhibits the reaction [Atrazine results in decreased expression of GPX8 mRNA]
CTD PMID:36216167 NCBI chr 2:44,676,448...44,680,042
Ensembl chr 2:46,409,139...46,413,406
JBrowse link
G Gsdmd gasdermin D multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GSDMD protein] CTD PMID:36610486 NCBI chr 7:107,542,489...107,547,051
Ensembl chr 7:109,422,910...109,430,722
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO lycopene inhibits the reaction [Zearalenone results in decreased activity of GSR protein] CTD PMID:25682699 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:65,185,574...65,228,394
JBrowse link
G Gss glutathione synthetase multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GSS mRNA] CTD PMID:35917956 PMID:36610486 NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:164,508,005...164,538,306
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions
increases expression
EXP [Glucose co-treated with Lycopene] results in increased expression of GSTP1 mRNA
Lycopene results in increased expression of GSTP1 mRNA
CTD PMID:38444079 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of HAVCR1 protein] CTD PMID:34670089 NCBI chr10:31,619,914...31,652,955
Ensembl chr10:31,619,897...31,653,268
JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions
decreases response to substance
ISO lycopene inhibits the reaction [HMGB1 protein results in increased expression of AGER protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of and results in increased secretion of PLA2G2A protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of and results in increased secretion of TNF protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of ICAM1 mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of ICAM1 protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of SELE mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of SELE protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of TLR2 protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of TLR4 protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of VCAM1 mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of VCAM1 protein]; lycopene inhibits the reaction [Lipopolysaccharides results in increased secretion of HMGB1 protein]
lycopene results in decreased susceptibility to HMGB1 protein
CTD PMID:22429818 NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327
Ensembl chr12:39,039,050...39,041,327
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
EXP
ISO
lycopene results in increased expression of HMOX1 mRNA; lycopene results in increased expression of HMOX1 protein
Lycopene inhibits the reaction [Atrazine results in increased expression of HMOX1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of HMOX1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of HMOX1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of HMOX1 protein]; Lycopene inhibits the reaction [Galactose results in decreased expression of HMOX1 mRNA]
[lycopene co-treated with Hydrogen Peroxide] results in increased expression of HMOX1 protein
lycopene promotes the reaction [Atrazine results in increased expression of HMOX1 mRNA]
CTD PMID:19551842 PMID:27102619 PMID:28974442 PMID:30360616 PMID:35917956 More... NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 multiple interactions EXP lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of HSD3B1 protein] CTD PMID:19071209 NCBI chr 2:188,858,574...188,864,694 JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 multiple interactions EXP lycopene inhibits the reaction [decamethrin results in increased expression of HSPA4 mRNA] CTD PMID:23076637 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,908,866...37,949,835
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions EXP Lycopene inhibits the reaction [Oxaliplatin results in increased expression of HSPA5 mRNA] CTD PMID:32544411 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of ICAM1 mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of ICAM1 protein]; lycopene inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA] CTD PMID:22429818 PMID:25551565 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions
decreases expression
increases expression
ISO
EXP
lycopene inhibits the reaction [IGF1 protein results in increased expression of CCND1 protein]; lycopene inhibits the reaction [IGF1 protein results in increased expression of CDKN1A protein]; lycopene inhibits the reaction [IGF1 protein results in increased phosphorylation of RB1 protein]
lycopene results in decreased expression of IGF1 mRNA
lycopene results in increased expression of IGF1 mRNA
CTD PMID:15084515 PMID:16565789 PMID:16886892 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764
JBrowse link
G Igf1r insulin-like growth factor 1 receptor decreases expression ISO lycopene results in decreased expression of IGF1R protein CTD PMID:17337101 NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:130,959,997...131,248,664
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 increases expression ISO lycopene results in increased expression of IGFBP2 protein CTD PMID:17337101 NCBI chr 9:81,864,811...81,892,179
Ensembl chr 9:81,864,783...81,892,171
JBrowse link
G Il10 interleukin 10 multiple interactions ISO [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]; lycopene promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]
Lycopene inhibits the reaction [Atrazine results in decreased expression of IL10 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL10 protein]; Lycopene inhibits the reaction [Zearalenone results in increased expression of IL10]
CTD PMID:25551565 PMID:25682699 PMID:36216167 PMID:36583613 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
JBrowse link
G Il18 interleukin 18 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL18 protein] CTD PMID:36610486 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of IL1B mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL1B mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL1B protein]; Lycopene inhibits the reaction [Galactose results in increased expression of IL1B protein]; Lycopene inhibits the reaction [Zearalenone results in increased expression of IL1B] CTD PMID:25682699 PMID:28974442 PMID:36216167 PMID:36610486 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Il2 interleukin 2 multiple interactions ISO lycopene inhibits the reaction [Zearalenone results in increased expression of IL2] CTD PMID:25682699 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672
JBrowse link
G Il6 interleukin 6 decreases expression
multiple interactions
EXP
ISO
lycopene results in decreased expression of IL6 mRNA
Lycopene inhibits the reaction [Atrazine results in increased expression of IL6 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of IL6 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL6 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL6 protein]; Lycopene inhibits the reaction [Zearalenone results in increased expression of IL6]
CTD PMID:15084515 PMID:25682699 PMID:36216167 PMID:36583613 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Irf3 interferon regulatory factor 3 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IRF3 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased phosphorylation of IRF3 protein] CTD PMID:36583613 NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:104,616,469...104,621,401
JBrowse link
G Irf7 interferon regulatory factor 7 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IRF7 mRNA] CTD PMID:36583613 NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:205,796,959...205,800,023
JBrowse link
G Ivl involucrin decreases expression ISO lycopene results in decreased expression of IVL protein CTD PMID:10769631 NCBI chr 2:180,842,307...180,854,646
Ensembl chr 2:180,842,307...180,846,578
JBrowse link
G Jak1 Janus kinase 1 increases expression ISO lycopene results in increased expression of JAK1 mRNA CTD PMID:16886892 NCBI chr 5:120,895,606...121,004,207
Ensembl chr 5:120,896,046...120,996,758
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression ISO lycopene results in decreased expression of JUN mRNA CTD PMID:16886892 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285
JBrowse link
G Jup junction plakoglobin multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of JUP protein]; Lycopene inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of JUP protein] CTD PMID:36087924 NCBI chr10:85,300,438...85,327,378
Ensembl chr10:85,800,814...85,827,429
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions
increases expression
ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of KEAP1 mRNA]; Lycopene inhibits the reaction [Atrazine results in decreased expression of KEAP1 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of KEAP1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of KEAP1 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of KEAP1 protein]
Lycopene results in increased expression of KEAP1 mRNA
CTD PMID:30360616 PMID:35917956 PMID:36216167 PMID:36610486 NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:28,044,555...28,054,042
JBrowse link
G Kif2a kinesin family member 2A increases expression ISO lycopene results in increased expression of KIF2A mRNA CTD PMID:16886892 NCBI chr 2:40,101,548...40,164,780
Ensembl chr 2:40,101,548...40,186,618
JBrowse link
G Kpna2 karyopherin subunit alpha 2 increases expression ISO lycopene results in increased expression of KPNA2 mRNA CTD PMID:16886892 NCBI chr10:91,933,951...91,946,115
Ensembl chr10:92,433,679...92,445,937
JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO lycopene results in increased expression of LDLR mRNA CTD PMID:16886892 NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:28,546,146...28,570,675
JBrowse link
G Lipa lipase A, lysosomal acid type increases expression ISO lycopene results in increased expression of LIPA mRNA CTD PMID:16886892 NCBI chr 1:232,024,351...232,057,735
Ensembl chr 1:241,437,524...241,470,740
JBrowse link
G Lpo lactoperoxidase multiple interactions ISO lycopene inhibits the reaction [Diethylnitrosamine results in increased expression of LPO protein] CTD PMID:24144777 NCBI chr10:73,104,170...73,124,683
Ensembl chr10:73,104,188...73,123,456
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased lipidation of and results in increased localization of MAP1LC3A protein] CTD PMID:33908429 NCBI chr 3:164,243,204...164,244,850
Ensembl chr 3:164,243,093...164,244,850
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions ISO
EXP
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased localization of MAP1LC3B protein]
[Glucose co-treated with Lycopene] results in increased expression of MAP1LC3B mRNA
CTD PMID:36583613 PMID:38444079 NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358
Ensembl chr16:66,574,407...66,584,358
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 increases expression ISO lycopene results in increased expression of MAP2K1 mRNA CTD PMID:16886892 NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 decreases expression ISO lycopene results in decreased expression of MAP2K2 protein CTD PMID:17337101 NCBI chr 7:9,241,449...9,264,216
Ensembl chr 7:9,241,310...9,260,940
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 decreases expression ISO lycopene results in decreased expression of MAP2K4 protein CTD PMID:17337101 NCBI chr10:50,842,348...50,947,063
Ensembl chr10:50,844,034...50,947,185
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 decreases expression ISO lycopene results in decreased expression of MAP2K6 protein CTD PMID:17337101 NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,872,546...95,987,721
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases expression
EXP
ISO
Lycopene inhibits the reaction [[Dietary Fats co-treated with Diethylnitrosamine] results in increased phosphorylation of MAPK1 protein]; Lycopene inhibits the reaction [bisphenol A results in decreased expression of MAPK1 protein]
Lycopene results in increased expression of MAPK1 protein
Lycopene inhibits the reaction [Atrazine results in increased expression of MAPK1 mRNA]
CTD PMID:19551842 PMID:30360616 PMID:32153214 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
JBrowse link
G Mapk14 mitogen activated protein kinase 14 decreases expression
multiple interactions
increases expression
ISO
EXP
lycopene results in decreased expression of MAPK14 protein
Lycopene inhibits the reaction [Oxaliplatin results in increased expression of MAPK14 protein]
lycopene results in increased expression of MAPK14 mRNA
CTD PMID:16886892 PMID:17337101 PMID:32544411 NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases expression ISO lycopene results in decreased expression of MAPK3 protein CTD PMID:17337101 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 decreases expression ISO lycopene results in decreased expression of MAPK8 protein CTD PMID:17337101 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427
JBrowse link
G Mfn1 mitofusin 1 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of MFN1 mRNA] CTD PMID:33908429 NCBI chr 2:117,240,525...117,288,017
Ensembl chr 2:117,241,759...117,290,190
JBrowse link
G Mfn2 mitofusin 2 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of MFN2 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of MFN2 protein] CTD PMID:33908429 NCBI chr 5:163,587,463...163,617,363
Ensembl chr 5:163,587,463...163,618,495
JBrowse link
G Mgat2 alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase increases expression ISO lycopene results in increased expression of MGAT2 mRNA CTD PMID:16886892 NCBI chr 6:93,392,416...93,394,905
Ensembl chr 6:93,390,555...93,395,176
JBrowse link
G Mill1 MHC I like leukocyte 1 increases expression ISO Lycopene results in increased expression of MICA mRNA CTD PMID:16886892 NCBI chr 1:87,500,591...87,526,983
Ensembl chr 1:87,500,676...87,526,981
JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions EXP Lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in increased expression of MKI67 protein] CTD PMID:33592256 NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593
JBrowse link
G Mlh1 mutL homolog 1 increases expression ISO lycopene results in increased expression of MLH1 mRNA CTD PMID:16886892 NCBI chr 8:120,074,871...120,112,109
Ensembl chr 8:120,065,900...120,112,011
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO lycopene inhibits the reaction [Acetaminophen results in increased activity of MMP2 protein] CTD PMID:27989599 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856
JBrowse link
G Msh2 mutS homolog 2 increases expression ISO lycopene results in increased expression of MSH2 mRNA CTD PMID:16886892 NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:12,567,368...12,626,503
JBrowse link
G Msh6 mutS homolog 6 increases expression ISO lycopene results in increased expression of MSH6 mRNA CTD PMID:16886892 NCBI chr 6:12,316,190...12,333,505
Ensembl chr 6:12,316,198...12,333,844
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression
multiple interactions
EXP
ISO
lycopene results in increased expression of NFE2L2 mRNA; lycopene results in increased expression of NFE2L2 protein
Lycopene inhibits the reaction [Atrazine affects the localization of NFE2L2 protein]; Lycopene inhibits the reaction [Atrazine results in increased expression of NFE2L2 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of NFE2L2 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NFE2L2 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NFE2L2 protein]
lycopene promotes the reaction [Atrazine results in increased expression of NFE2L2 mRNA]
CTD PMID:19551842 PMID:27102619 PMID:30360616 PMID:35917956 PMID:36216167 More... NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions EXP lycopene inhibits the reaction [Atrazine results in increased expression of NFKB1 mRNA] CTD PMID:27102619 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:226,689,745...226,783,088
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; lycopene inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA] CTD PMID:25551565 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NLRP3 protein] CTD PMID:36610486 NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394
JBrowse link
G Nos1 nitric oxide synthase 1 decreases expression ISO lycopene results in decreased expression of NOS1 mRNA CTD PMID:16886892 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:44,287,614...44,371,837
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of NQO1 protein]; Lycopene inhibits the reaction [Atrazine results in increased expression of NQO1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NQO1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NQO1 protein]; Lycopene inhibits the reaction [Galactose results in decreased expression of NQO1 mRNA] CTD PMID:28974442 PMID:30360616 PMID:35917956 PMID:36216167 PMID:36610486 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 increases expression ISO Lycopene increases expression of NR1H3 protein in macrophages RGD PMID:21208793 RGD:401842374 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:97,614,616...97,624,532
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases expression
ISO Lycopene inhibits the reaction [Atrazine results in increased expression of NR1I2 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of NR1I2 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NR1I2 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NR1I2 protein]
Lycopene results in increased expression of NR1I2 mRNA; Lycopene results in increased expression of NR1I2 protein
CTD PMID:36216167 PMID:36403809 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:75,965,632...76,002,380
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions
increases expression
ISO Lycopene inhibits the reaction [Atrazine results in increased expression of NR1I3 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of and results in increased localization of NR1I3 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of and results in increased localization of NR1I3 protein]
Lycopene results in increased expression of NR1I3 mRNA
CTD PMID:36216167 PMID:36403809 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:86,165,349...86,170,370
JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 multiple interactions ISO [Lycopene co-treated with Atrazine] results in increased expression of NR3C2 mRNA CTD PMID:36216167 NCBI chr19:47,619,853...47,964,089
Ensembl chr19:47,619,853...47,964,078
JBrowse link
G Nrf1 nuclear respiratory factor 1 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NRF1 mRNA] CTD PMID:33908429 NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:59,632,372...59,738,353
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 increases expression
multiple interactions
EXP Lycopene results in increased expression of NTRK2 protein
Lycopene inhibits the reaction [bisphenol A results in decreased expression of NTRK2 protein]
CTD PMID:32153214 NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,564,570...5,874,628
JBrowse link
G Nup214 nucleoporin 214 decreases expression ISO lycopene results in decreased expression of NUP214 mRNA CTD PMID:16886892 NCBI chr 3:15,255,111...15,340,568
Ensembl chr 3:35,652,858...35,739,192
JBrowse link
G Nup62 nucleoporin 62 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NUP62 mRNA] CTD PMID:35917956 NCBI chr 1:104,435,532...104,451,392
Ensembl chr 1:104,432,093...104,452,710
JBrowse link
G Ocln occludin multiple interactions ISO Lycopene inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of OCLN protein] CTD PMID:36087924 NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:33,391,303...33,430,411
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of OPA1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of OPA1 protein] CTD PMID:33908429 NCBI chr11:84,612,943...84,690,025
Ensembl chr11:84,615,340...84,689,955
JBrowse link
G P22k15 cystatin related protein 2 decreases expression EXP lycopene results in decreased expression of P22K15 mRNA CTD PMID:15084515 NCBI chr 3:136,960,300...136,967,358
Ensembl chr 3:157,420,933...157,427,988
JBrowse link
G Pah phenylalanine hydroxylase decreases expression ISO lycopene results in decreased expression of PAH mRNA CTD PMID:19555370 NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:23,792,781...23,885,627
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions EXP lycopene inhibits the reaction [decamethrin results in increased activity of PARP1 protein] CTD PMID:23076637 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
JBrowse link
G Pbsn probasin decreases expression EXP Lycopene results in decreased expression of PBSN mRNA CTD PMID:15084515 NCBI chr  X:41,914,346...41,929,591
Ensembl chr  X:45,792,738...45,807,983
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP lycopene inhibits the reaction [[Diethylnitrosamine co-treated with Dietary Fats] results in increased expression of PCNA protein] CTD PMID:19551842 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
JBrowse link
G Pink1 PTEN induced kinase 1 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PINK1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PINK1 protein] CTD PMID:33908429 PMID:36583613 NCBI chr 5:155,813,838...155,825,950
Ensembl chr 5:155,813,838...155,825,950
JBrowse link
G Pla2g2a phospholipase A2 group IIA multiple interactions ISO lycopene inhibits the reaction [HMGB1 protein results in increased expression of and results in increased secretion of PLA2G2A protein] CTD PMID:22429818 NCBI chr 5:156,359,725...156,362,302
Ensembl chr 5:156,359,725...156,362,297
JBrowse link
G Pomc proopiomelanocortin multiple interactions EXP lycopene inhibits the reaction [Atrazine results in increased secretion of POMC protein modified form] CTD PMID:27102619 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:32,659,346...32,665,173
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO Lycopene affects the reaction [Atrazine affects the expression of PPARA mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of PPARA protein] CTD PMID:36216167 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression
multiple interactions
ISO Lycopene results in increased expression of PPARG mRNA
[Lycopene co-treated with Atrazine] results in increased expression of PPARG mRNA
CTD PMID:36216167 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PPARGC1A mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PPARGC1A protein] CTD PMID:33908429 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213
JBrowse link
G Prdx1 peroxiredoxin 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of PRDX1 mRNA] CTD PMID:36216167 NCBI chr 5:135,383,906...135,399,504
Ensembl chr 5:135,383,906...135,399,504
JBrowse link
G Prdx2 peroxiredoxin 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of PRDX2 mRNA] CTD PMID:36216167 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:40,084,430...40,091,006
JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 multiple interactions
increases expression
increases phosphorylation
ISO Lycopene inhibits the reaction [Atrazine results in increased expression of PRKAA2 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased phosphorylation of PRKAA2 protein]
Lycopene results in increased expression of PRKAA2 mRNA
Lycopene results in increased phosphorylation of PRKAA2 protein
CTD PMID:30360616 NCBI chr 5:125,036,945...125,109,010
Ensembl chr 5:125,042,179...125,108,324
JBrowse link
G Prkab1 protein kinase AMP-activated non-catalytic subunit beta 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of PRKAB1 mRNA] CTD PMID:30360616 NCBI chr12:40,588,140...40,598,673
Ensembl chr12:46,249,010...46,259,482
JBrowse link
G Prkab2 protein kinase AMP-activated non-catalytic subunit beta 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of PRKAB2 mRNA] CTD PMID:30360616 NCBI chr 2:185,257,218...185,272,846
Ensembl chr 2:187,945,982...187,961,608
JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 multiple interactions ISO Lycopene affects the reaction [Atrazine results in increased expression of PRKAG2 mRNA] CTD PMID:30360616 NCBI chr 4:10,010,890...10,252,155
Ensembl chr 4:10,744,588...10,985,939
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit decreases expression ISO lycopene results in decreased expression of PRKDC mRNA CTD PMID:16886892 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:98,544,954...98,762,108
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PRKN mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PRKN protein] CTD PMID:36583613 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:51,210,330...52,430,304
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of PTGS2 mRNA]; Lycopene inhibits the reaction [Galactose results in increased expression of PTGS2 mRNA] CTD PMID:28974442 PMID:36216167 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
JBrowse link
G Pycard PYD and CARD domain containing multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PYCARD mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PYCARD protein] CTD PMID:36610486 NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:192,032,124...192,033,419
JBrowse link
G Rad50 RAD50 double strand break repair protein increases expression ISO lycopene results in increased expression of RAD50 mRNA CTD PMID:16886892 NCBI chr10:38,310,147...38,362,100
Ensembl chr10:38,310,147...38,362,100
JBrowse link
G Rassf7 Ras association domain family member 7 increases expression ISO lycopene results in increased expression of RASSF7 mRNA CTD PMID:16886892 NCBI chr 1:196,319,600...196,323,787
Ensembl chr 1:205,747,654...205,753,360
JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions
decreases phosphorylation
ISO lycopene inhibits the reaction [Genistein results in increased phosphorylation of and results in decreased activity of RB1 protein]; lycopene inhibits the reaction [IGF1 protein results in increased phosphorylation of RB1 protein]
lycopene results in decreased phosphorylation of RB1 protein
CTD PMID:16565789 PMID:17051425 PMID:17337101 NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857
JBrowse link
G Rdx radixin decreases expression ISO lycopene results in decreased expression of RDX mRNA CTD PMID:16886892 NCBI chr 8:61,275,792...61,348,260
Ensembl chr 8:61,274,460...61,333,967
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased phosphorylation of RELA protein] CTD PMID:36583613 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 multiple interactions EXP [Glucose co-treated with Lycopene] results in increased expression of RIPK1 mRNA CTD PMID:38444079 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:31,044,994...31,077,167
JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 multiple interactions EXP [Glucose co-treated with Lycopene] results in increased expression of RIPK3 mRNA CTD PMID:38444079 NCBI chr15:33,253,071...33,262,025
Ensembl chr15:33,253,071...33,262,025
JBrowse link
G Rps6ka1 ribosomal protein S6 kinase A1 decreases expression ISO lycopene results in decreased expression of RPS6KA1 protein CTD PMID:17337101 NCBI chr 5:146,079,018...146,118,272
Ensembl chr 5:151,362,819...151,476,044
JBrowse link
G Rps6ka3 ribosomal protein S6 kinase A3 decreases expression ISO lycopene results in decreased expression of RPS6KA3 protein CTD PMID:17337101 NCBI chr  X:35,517,306...35,623,296
Ensembl chr  X:39,325,926...39,433,678
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 increases expression ISO lycopene results in increased expression of RRM2 mRNA CTD PMID:16886892 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:47,067,690...47,075,370
JBrowse link
G Sbp spermine binding protein decreases expression EXP lycopene results in decreased expression of SBP mRNA CTD PMID:15084515 NCBI chr10:12,946,036...12,968,439
Ensembl chr10:13,469,303...13,473,016
JBrowse link
G Scgb1d2 secretoglobin, family 1D, member 2 decreases expression EXP lycopene results in decreased expression of SCGB1D2 mRNA CTD PMID:15084515 NCBI chr 1:215,653,464...215,658,101
Ensembl chr 1:215,653,464...215,656,710
JBrowse link
G Scgb1d4 secretoglobin family 1D member 4 decreases expression EXP lycopene results in decreased expression of SCGB1D4 mRNA CTD PMID:15084515 NCBI chr 1:215,755,363...215,758,238
Ensembl chr 1:215,755,363...215,758,238
JBrowse link
G Scgb2a1 secretoglobin, family 2A, member 1 decreases expression EXP Lycopene results in decreased expression of SCGB2A2 mRNA CTD PMID:15084515 NCBI chr 1:215,922,751...215,926,114
Ensembl chr 1:215,794,572...215,797,345
Ensembl chr 1:215,794,572...215,797,345
JBrowse link
G Sele selectin E multiple interactions ISO [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of SELE mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of SELE protein]; lycopene inhibits the reaction [TNF protein results in increased expression of SELE mRNA] CTD PMID:22429818 PMID:25551565 NCBI chr13:78,935,997...78,945,905
Ensembl chr13:78,936,036...78,945,903
JBrowse link
G Selenop selenoprotein P decreases expression ISO lycopene results in decreased expression of SELENOP mRNA CTD PMID:16886892 NCBI chr 2:52,498,123...52,508,409
Ensembl chr 2:54,225,152...54,236,019
JBrowse link
G Selenos selenoprotein S increases expression EXP Lycopene results in increased expression of SELENOS mRNA CTD PMID:38444079 NCBI chr 1:119,659,779...119,669,546
Ensembl chr 1:129,070,230...129,077,991
JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO lycopene inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT1 protein]
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SIRT1 protein]
CTD PMID:28974442 PMID:33908429 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000
JBrowse link
G Sirt3 sirtuin 3 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SIRT3 protein] CTD PMID:33908429 NCBI chr 1:205,371,703...205,394,145
Ensembl chr 1:205,371,710...205,394,076
JBrowse link
G Skap2 src kinase associated phosphoprotein 2 decreases expression ISO lycopene results in decreased expression of SKAP2 mRNA CTD PMID:19555370 NCBI chr 4:80,948,832...81,100,900
Ensembl chr 4:82,263,709...82,432,886
JBrowse link
G Smad3 SMAD family member 3 increases expression ISO lycopene results in increased expression of SMAD3 mRNA CTD PMID:16886892 NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:73,024,760...73,132,324
JBrowse link
G Smc1a structural maintenance of chromosomes 1A decreases expression ISO lycopene results in decreased expression of SMC1A mRNA CTD PMID:16886892 NCBI chr  X:24,582,732...24,627,462
Ensembl chr  X:24,582,690...24,627,462
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
increases expression
ISO
EXP
Lycopene inhibits the reaction [Atrazine results in increased expression of SOD1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SOD1 mRNA]; Lycopene promotes the reaction [Diethylhexyl Phthalate results in decreased expression of SOD1 protein]
[Glucose co-treated with Lycopene] results in increased expression of SOD1 mRNA
Lycopene results in increased expression of SOD1 mRNA
CTD PMID:35917956 PMID:36216167 PMID:36610486 PMID:38444079 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression
ISO
EXP
Lycopene inhibits the reaction [Atrazine results in increased expression of SOD2 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SOD2 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SOD2 protein]
Lycopene results in increased expression of SOD2 mRNA
[Glucose co-treated with Lycopene] results in increased expression of SOD2 mRNA
CTD PMID:33908429 PMID:35917956 PMID:36216167 PMID:36610486 PMID:38444079 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168
JBrowse link
G Sod3 superoxide dismutase 3 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of SOD3 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SOD3 mRNA] CTD PMID:35917956 PMID:36216167 PMID:36610486 NCBI chr14:62,822,865...62,828,602
Ensembl chr14:62,811,177...62,829,125
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO
EXP
Lycopene inhibits the reaction [Atrazine results in increased expression of SQSTM1 mRNA alternative form]; Lycopene inhibits the reaction [Atrazine results in increased expression of SQSTM1 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of SQSTM1 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SQSTM1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SQSTM1 protein]
[Glucose co-treated with Lycopene] results in increased expression of SQSTM1 mRNA
CTD PMID:30360616 PMID:36583613 PMID:38444079 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:35,026,598...35,037,750
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 decreases expression EXP lycopene results in decreased expression of SRD5A1 mRNA CTD PMID:15084515 NCBI chr 1:35,514,914...35,548,898
Ensembl chr 1:35,514,846...35,548,903
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions EXP lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of STAR protein]; lycopene inhibits the reaction [decamethrin results in decreased expression of STAR mRNA] CTD PMID:19071209 PMID:23076637 NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447
JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases expression ISO lycopene results in increased expression of STAT3 mRNA CTD PMID:16886892 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359
JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of STING1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of STING1 protein] CTD PMID:36583613 NCBI chr18:27,606,196...27,612,544
Ensembl chr18:27,606,196...27,611,947
JBrowse link
G Tbk1 TANK-binding kinase 1 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased phosphorylation of TBK1 protein] CTD PMID:36583613 NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:58,963,325...58,996,357
JBrowse link
G Tfam transcription factor A, mitochondrial multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of TFAM mRNA] CTD PMID:33908429 NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,355,363...17,369,877
JBrowse link
G Tff1 trefoil factor 1 decreases expression ISO lycopene results in decreased expression of TFF1 mRNA CTD PMID:16886892 NCBI chr20:9,237,095...9,240,956
Ensembl chr20:9,237,095...9,240,956
JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 decreases expression ISO lycopene results in decreased expression of TFPI2 mRNA CTD PMID:16886892 NCBI chr 4:31,981,786...31,986,707
Ensembl chr 4:32,936,854...32,941,426
JBrowse link
G Tgfa transforming growth factor alpha increases expression ISO lycopene results in increased expression of TGFA mRNA CTD PMID:16886892 NCBI chr 4:120,175,549...120,258,342
Ensembl chr 4:120,175,593...120,258,339
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions ISO [Lycopene co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of TJP1 protein; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of TJP1 protein] CTD PMID:36087924 NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:128,260,330...128,505,158
JBrowse link
G Tlr2 toll-like receptor 2 multiple interactions ISO lycopene inhibits the reaction [HMGB1 protein results in increased expression of TLR2 protein]; lycopene inhibits the reaction [Lipopolysaccharides results in increased expression of TLR2 protein] CTD PMID:22429818 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:171,497,060...171,520,194
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO lycopene inhibits the reaction [HMGB1 protein results in increased expression of TLR4 protein]; lycopene inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]
Lycopene affects the reaction [Atrazine affects the expression of TLR4 mRNA]
CTD PMID:22429818 PMID:36216167 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO
[Lycopene co-treated with Diethylnitrosamine] results in increased expression of TNF mRNA; Lycopene inhibits the reaction [Oxaliplatin results in increased expression of TNF protein]
Lycopene inhibits the reaction [Atrazine results in increased expression of TNF mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of TNF protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of TNF mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of TNF protein]; Lycopene inhibits the reaction [Galactose results in increased expression of TNF protein]; Lycopene inhibits the reaction [Zearalenone results in increased expression of TNF]
[Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of CXCL8 protein]; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of TNF protein]; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of TNF mRNA]; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of and results in increased secretion of TNF protein]; lycopene inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of CXCL8 protein]; lycopene inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of TNF protein]; lycopene inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; lycopene inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; lycopene inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; lycopene inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; lycopene inhibits the reaction [TNF protein results in increased expression of TNF mRNA]; lycopene promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]
CTD PMID:19551842 PMID:22429818 PMID:25551565 PMID:25682699 PMID:28974442 More... NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tp53 tumor protein p53 decreases expression
multiple interactions
ISO lycopene results in decreased expression of TP53 mRNA
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of TP53 mRNA]
CTD PMID:16886892 PMID:36583613 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link
G Traf6 TNF receptor associated factor 6 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of TRAF6 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of TRAF6 protein] CTD PMID:36216167 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:108,418,513...108,443,328
JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions EXP Lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in increased expression of TSHB protein] CTD PMID:33592256 NCBI chr 2:192,913,171...192,918,054
Ensembl chr 2:192,913,171...192,942,984
JBrowse link
G Txn1 thioredoxin 1 multiple interactions ISO Lycopene affects the reaction [Atrazine affects the expression of TXN1 mRNA] CTD PMID:36216167 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:77,507,321...77,520,307
JBrowse link
G Txn2 thioredoxin 2 multiple interactions
decreases expression
ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of TXN2 mRNA]
Lycopene results in decreased expression of TXN2 mRNA
CTD PMID:36216167 NCBI chr 7:109,496,772...109,510,378
Ensembl chr 7:111,386,805...111,390,022
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO lycopene inhibits the reaction [HMGB1 protein results in increased expression of VCAM1 mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of VCAM1 protein] CTD PMID:22429818 NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:206,723,044...206,742,801
JBrowse link
G Vcp valosin-containing protein increases expression ISO lycopene results in increased expression of VCP mRNA CTD PMID:16886892 NCBI chr 5:62,005,984...62,025,387
Ensembl chr 5:62,005,985...62,025,387
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP Lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in increased expression of VEGFA protein] CTD PMID:33592256 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
JBrowse link
G Vim vimentin multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of VIM protein]; Lycopene inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of VIM protein] CTD PMID:36087924 NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746
JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of XBP1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of XBP1 protein] CTD PMID:36583613 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:84,604,107...84,609,706
JBrowse link
Torularhodin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaa1a acetyl-CoA acyltransferase 1A multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in decreased expression of ACAA1A protein] CTD PMID:36234935 NCBI chr 8:119,079,401...119,088,626
Ensembl chr 8:127,956,129...127,966,241
JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in decreased expression of ACAA1B protein] CTD PMID:36234935 NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:127,750,743...127,759,569
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in increased expression of APEX1 protein] CTD PMID:36234935 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:26,618,224...26,620,329
JBrowse link
G Apoa2 apolipoprotein A2 multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in decreased expression of APOA2 protein] CTD PMID:36234935 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:86,174,741...86,179,410
JBrowse link
G Apoa4 apolipoprotein A4 multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in decreased expression of APOA4 protein] CTD PMID:36234935 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:55,434,168...55,438,164
JBrowse link
G Asgr1 asialoglycoprotein receptor 1 multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in decreased expression of ASGR1 protein] CTD PMID:36234935 NCBI chr10:54,775,727...54,779,642
Ensembl chr10:55,274,706...55,278,322
JBrowse link
G Asl argininosuccinate lyase multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in increased expression of ASL protein] CTD PMID:36234935 NCBI chr12:26,659,664...26,677,136
Ensembl chr12:32,295,633...32,317,261
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
ISO torularhodin results in increased expression of BAX mRNA
torularhodin inhibits the reaction [Hydrogen Peroxide results in decreased expression of BAX mRNA]
torularhodin inhibits the reaction [Dietary Fats results in increased expression of BAX protein]; torularhodin inhibits the reaction [Galactose results in increased expression of BAX protein]
CTD PMID:26742427 PMID:28112004 PMID:31431007 PMID:36234935 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO torularhodin results in decreased expression of BCL2 mRNA
torularhodin inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 mRNA]
CTD PMID:26742427 PMID:28112004 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in increased expression of BHMT protein] CTD PMID:36234935 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:26,594,854...26,614,715
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
ISO torularhodin inhibits the reaction [Dietary Fats results in decreased expression of CASP3 protein]
torularhodin results in increased expression of CASP3 mRNA
CTD PMID:26742427 PMID:36234935 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Casp8 caspase 8 increases expression ISO torularhodin results in increased expression of CASP8 mRNA CTD PMID:26742427 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:67,758,033...67,806,699
JBrowse link
G Casp9 caspase 9 increases expression ISO torularhodin results in increased expression of CASP9 mRNA CTD PMID:26742427 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cat catalase multiple interactions ISO torularhodin inhibits the reaction [Galactose results in decreased activity of CAT protein]
torularhodin inhibits the reaction [Hydrogen Peroxide results in decreased activity of CAT protein]
CTD PMID:28112004 PMID:31431007 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in decreased expression of CPT1A protein] CTD PMID:36234935 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:209,993,875...210,056,326
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in decreased expression of CYP7A1 protein] CTD PMID:36234935 NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:24,174,505...24,184,202
JBrowse link
G Ddc dopa decarboxylase multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in decreased expression of DDC protein] CTD PMID:36234935 NCBI chr14:90,592,304...90,682,830
Ensembl chr14:90,592,304...90,682,806
JBrowse link
G Dnm1l dynamin 1-like multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in decreased expression of DNM1L protein] CTD PMID:36234935 NCBI chr11:98,084,049...98,135,663
Ensembl chr11:98,085,397...98,137,420
JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in decreased expression of ECI1 protein] CTD PMID:36234935 NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,961,218...13,974,773
JBrowse link
G Eci2 enoyl-CoA delta isomerase 2 multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in decreased expression of ECI2 protein] CTD PMID:36234935 NCBI chr17:29,850,884...29,886,781
Ensembl chr17:30,076,524...30,092,161
JBrowse link
G Emc1 ER membrane protein complex subunit 1 multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in decreased expression of EMC1 protein] CTD PMID:36234935 NCBI chr 5:151,608,557...151,633,888
Ensembl chr 5:156,891,773...156,917,092
JBrowse link
G Ephx1 epoxide hydrolase 1 multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in decreased expression of EPHX1 protein]; torularhodin inhibits the reaction [Dietary Fats results in increased expression of EPHX1 protein] CTD PMID:36234935 NCBI chr13:95,246,079...95,275,852
Ensembl chr13:95,246,080...95,321,981
JBrowse link
G Fabp1 fatty acid binding protein 1 multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in increased expression of FABP1 protein] CTD PMID:36234935 NCBI chr 4:104,744,302...104,753,119
Ensembl chr 4:104,744,309...104,753,113
JBrowse link
G Fabp2 fatty acid binding protein 2 multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in increased expression of FABP2 protein] CTD PMID:36234935 NCBI chr 2:211,040,032...211,044,089
Ensembl chr 2:213,724,629...213,728,686
JBrowse link
G Fabp5 fatty acid binding protein 5 multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in decreased expression of FABP5 protein] CTD PMID:36234935 NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:93,672,458...93,676,127
JBrowse link
G Fadd Fas associated via death domain multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in decreased expression of FADD protein] CTD PMID:36234935 NCBI chr 1:209,169,245...209,175,423
Ensembl chr 1:209,169,318...209,174,976
JBrowse link
G Faf1 Fas associated factor 1 multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in increased expression of FAF1 protein] CTD PMID:36234935 NCBI chr 5:124,426,032...124,790,014
Ensembl chr 5:129,654,445...130,020,516
JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in increased expression of FAS protein] CTD PMID:36234935 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104
JBrowse link
G Gk glycerol kinase multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in decreased expression of GK protein] CTD PMID:36234935 NCBI chr  X:50,162,089...50,238,707
Ensembl chr  X:54,112,214...54,196,701
JBrowse link
G Glod4 glyoxalase domain containing 4 multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in increased expression of GLOD4 protein] CTD PMID:36234935 NCBI chr10:61,575,770...61,594,111 JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions ISO torularhodin inhibits the reaction [Ethanol results in increased activity of GOT1 protein] CTD PMID:31374322 NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:252,284,434...252,329,871
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO torularhodin inhibits the reaction [Ethanol results in increased activity of GPT protein] CTD PMID:31374322 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160
JBrowse link
G Gsdmd gasdermin D multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in increased expression of GSDMD protein] CTD PMID:36234935 NCBI chr 7:107,542,489...107,547,051
Ensembl chr 7:109,422,910...109,430,722
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions EXP torularhodin inhibits the reaction [Hydrogen Peroxide results in increased expression of GSK3B mRNA] CTD PMID:25975093 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in increased expression of GSTP1 protein] CTD PMID:36234935 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP
ISO
torularhodin inhibits the reaction [Hydrogen Peroxide results in decreased expression of HMOX1 mRNA]
torularhodin inhibits the reaction [Galactose results in decreased expression of HMOX1 mRNA]; torularhodin inhibits the reaction [Galactose results in decreased expression of HMOX1 protein]
CTD PMID:25975093 PMID:31431007 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in increased expression of ICAM1 protein] CTD PMID:36234935 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO torularhodin inhibits the reaction [Ethanol results in increased expression of IL1B protein]; torularhodin inhibits the reaction [Galactose results in increased secretion of IL1B protein]; torularhodin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] CTD PMID:31374322 PMID:31431007 PMID:36771110 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Il6 interleukin 6 multiple interactions ISO torularhodin inhibits the reaction [Galactose results in increased secretion of IL6 protein] CTD PMID:31431007 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Insr insulin receptor multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in increased expression of INSR protein] CTD PMID:36234935 NCBI chr12:5,991,135...6,129,275
Ensembl chr12:5,981,835...6,128,803
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions EXP torularhodin inhibits the reaction [Hydrogen Peroxide results in increased expression of KEAP1 mRNA] CTD PMID:25975093 NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:28,044,555...28,054,042
JBrowse link
G Lrp1 LDL receptor related protein 1 multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in increased expression of LRP1 protein] CTD PMID:36234935 NCBI chr 7:65,265,639...65,346,196
Ensembl chr 7:65,265,639...65,346,196
JBrowse link
G Manf mesencephalic astrocyte-derived neurotrophic factor multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in increased expression of MANF protein] CTD PMID:36234935 NCBI chr 8:107,500,856...107,551,595
Ensembl chr 8:116,427,048...116,429,910
JBrowse link
G Me1 malic enzyme 1 multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in increased expression of ME1 protein] CTD PMID:36234935 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:96,429,057...96,540,275
JBrowse link
G Mif macrophage migration inhibitory factor multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in decreased expression of MIF protein] CTD PMID:36234935 NCBI chr20:12,767,138...12,791,222
Ensembl chr 4:134,041,774...134,042,121
Ensembl chr20:134,041,774...134,042,121
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions ISO torularhodin inhibits the reaction [Lipopolysaccharides results in increased expression of MYD88 mRNA] CTD PMID:36771110 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:127,952,161...127,956,230
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in decreased expression of NAMPT protein] CTD PMID:36234935 NCBI chr 6:55,152,756...55,189,547
Ensembl chr 6:55,151,926...55,189,544
JBrowse link
G Ndufs8 NADH:ubiquinone oxidoreductase core subunit S8 multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in decreased expression of NDUFS8 protein] CTD PMID:36234935 NCBI chr 1:201,140,585...201,144,573
Ensembl chr 1:210,569,824...210,572,971
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP
ISO
torularhodin inhibits the reaction [Hydrogen Peroxide results in decreased expression of NFE2L2 mRNA]
torularhodin inhibits the reaction [Galactose results in decreased expression of NFE2L2 mRNA]; torularhodin inhibits the reaction [Galactose results in decreased expression of NFE2L2 protein]
CTD PMID:25975093 PMID:31431007 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO torularhodin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA] CTD PMID:36771110 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO
EXP
torularhodin inhibits the reaction [Galactose results in decreased expression of NQO1 mRNA]
torularhodin inhibits the reaction [Hydrogen Peroxide results in decreased expression of NQO1 mRNA]
CTD PMID:25975093 PMID:31431007 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
JBrowse link
G Ocln occludin multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in increased expression of OCLN protein] CTD PMID:36234935 NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:33,391,303...33,430,411
JBrowse link
G Optn optineurin multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in decreased expression of OPTN protein] CTD PMID:36234935 NCBI chr17:73,209,572...73,260,251
Ensembl chr17:78,118,866...78,169,543
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in decreased expression of PCK1 protein] CTD PMID:36234935 NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:182,348,572...182,354,561
JBrowse link
G Plin2 perilipin 2 multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in increased expression of PLIN2 protein] CTD PMID:36234935 NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:106,202,634...106,258,878
JBrowse link
G Plin4 perilipin 4 multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in increased expression of PLIN4 protein] CTD PMID:36234935 NCBI chr 9:929,168...938,062
Ensembl chr 9:1,016,302...1,025,368
JBrowse link
G Plin5 perilipin 5 multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in increased expression of PLIN5 protein] CTD PMID:36234935 NCBI chr 9:939,745...946,188
Ensembl chr 9:1,026,307...1,033,284
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in increased expression of PPARA protein] CTD PMID:36234935 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714
JBrowse link
G Ppm1k protein phosphatase, Mg2+/Mn2+ dependent, 1K multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in increased expression of PPM1K protein] CTD PMID:36234935 NCBI chr 4:87,612,198...87,638,993
Ensembl chr 4:88,942,386...88,969,136
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO torularhodin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] CTD PMID:36771110 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in decreased expression of PTK2B protein] CTD PMID:36234935 NCBI chr15:44,536,275...44,656,754
Ensembl chr15:44,531,249...44,656,806
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO torularhodin inhibits the reaction [Galactose results in increased expression of RELA protein] CTD PMID:31431007 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in increased expression of ROCK1 protein] CTD PMID:36234935 NCBI chr18:1,387,360...1,509,218
Ensembl chr18:1,387,360...1,509,147
JBrowse link
G Rps10 ribosomal protein S10 multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in decreased expression of RPS10 protein] CTD PMID:36234935 NCBI chr20:5,694,313...5,698,922
Ensembl chr20:5,696,135...5,700,150
Ensembl chr 6:5,696,135...5,700,150
JBrowse link
G Sec61b SEC61 translocon subunit beta multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in decreased expression of SEC61B protein] CTD PMID:36234935 NCBI chr 5:61,773,594...61,781,804
Ensembl chr 5:66,569,196...66,580,028
JBrowse link
G Slc27a4 solute carrier family 27 member 4 multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in increased expression of SLC27A4 protein] CTD PMID:36234935 NCBI chr 3:33,472,903...33,485,824
Ensembl chr 3:33,472,903...33,485,824
JBrowse link
G Slc27a5 solute carrier family 27 member 5 multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in increased expression of SLC27A5 protein] CTD PMID:36234935 NCBI chr 1:73,616,556...73,627,149
Ensembl chr 1:82,688,750...82,699,358
JBrowse link
G Sorbs1 sorbin and SH3 domain containing 1 multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in increased expression of SORBS1 protein] CTD PMID:36234935 NCBI chr 1:249,057,324...249,279,703
Ensembl chr 1:249,057,324...249,279,608
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in increased expression of STAT3 protein] CTD PMID:36234935 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO torularhodin inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA] CTD PMID:36771110 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007
JBrowse link
G Tmem30a transmembrane protein 30A multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in decreased expression of TMEM30A protein] CTD PMID:36234935 NCBI chr 8:80,728,749...80,757,197
Ensembl chr 8:89,608,975...89,633,291
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO torularhodin inhibits the reaction [Ethanol results in increased expression of TNF protein]; torularhodin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] CTD PMID:31374322 PMID:36771110 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Ugt2a3 UDP glucuronosyltransferase family 2 member A3 multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in decreased expression of UGT2A3 protein] CTD PMID:36234935 NCBI chr14:20,572,793...20,590,795
Ensembl chr14:20,851,969...20,869,973
JBrowse link
G Vamp8 vesicle-associated membrane protein 8 multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in decreased expression of VAMP8 protein] CTD PMID:36234935 NCBI chr 4:106,000,570...106,011,081
Ensembl chr 4:106,000,570...106,011,073
JBrowse link
G Vnn1 vanin 1 multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in increased expression of VNN1 protein] CTD PMID:36234935 NCBI chr 1:23,356,324...23,366,629
Ensembl chr 1:23,356,330...23,366,629
JBrowse link
G Yap1 Yes1 associated transcriptional regulator multiple interactions ISO torularhodin inhibits the reaction [Dietary Fats results in decreased expression of YAP1 protein] CTD PMID:36234935 NCBI chr 8:13,380,551...13,451,640
Ensembl chr 8:13,380,551...13,451,437
JBrowse link
torulene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
ISO torulene results in increased expression of BAX mRNA
torulene inhibits the reaction [Hydrogen Peroxide results in decreased expression of BAX mRNA]
CTD PMID:26742427 PMID:28112004 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO torulene results in decreased expression of BCL2 mRNA
torulene inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 mRNA]
CTD PMID:26742427 PMID:28112004 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Casp3 caspase 3 increases expression ISO torulene results in increased expression of CASP3 mRNA CTD PMID:26742427 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Casp8 caspase 8 increases expression ISO torulene results in increased expression of CASP8 mRNA CTD PMID:26742427 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:67,758,033...67,806,699
JBrowse link
G Casp9 caspase 9 increases expression ISO torulene results in increased expression of CASP9 mRNA CTD PMID:26742427 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cat catalase multiple interactions ISO torulene inhibits the reaction [Hydrogen Peroxide results in decreased activity of CAT protein] CTD PMID:28112004 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    chemical entity 20860
      atom 20860
        nonmetal atom 20766
          carbon atom 20710
            organic molecular entity 20710
              isoprenoid 14163
                terpene 14163
                  tetraterpene 678
                    carotene 678
                      acyclic carotene + 272
                      carotenoid + 678
                      cyclic carotene + 276
                      torulene + 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    main group molecular entity 20781
                      s-block molecular entity 20574
                        hydrogen molecular entity 20558
                          hydrides 19693
                            organic hydride 19079
                              organic fundamental parent 19079
                                hydrocarbon 18731
                                  terpene 14163
                                    tetraterpene 678
                                      carotene 678
                                        acyclic carotene + 272
                                        carotenoid + 678
                                        cyclic carotene + 276
                                        torulene + 6
paths to the root