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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:butenedioic acid
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Accession:CHEBI:22958 term browser browse the term
Definition:A C4-dicarboxylic acid that has formula C4H4O4.
Synonyms:exact_synonym: but-2-enedioic acid
 related_synonym: 2-butenedioic acid;   Formula=C4H4O4;   InChI=1S/C4H4O4/c5-3(6)1-2-4(7)8/h1-2H,(H,5,6)(H,7,8);   InChIKey=VZCYOOQTPOCHFL-UHFFFAOYSA-N;   SMILES=[H]C(=C([H])C(O)=O)C(O)=O
 xref: Beilstein:8132074
 cyclic_relationship: is_conjugate_acid_of CHEBI:37155


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diethyl maleate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRDX2 peroxiredoxin 2 decreases activity EXP diethyl maleate results in decreased activity of PRDX2 protein CTD PMID:19208552 NCBI chr 2:66,207,829...66,211,474
Ensembl chr 2:66,207,828...66,212,009 		JBrowse link
maleic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACO2 aconitase 2 multiple interactions
decreases activity 		EXP Curcumin inhibits the reaction [maleic acid results in decreased activity of ACO2 protein] CTD PMID:25119790 NCBI chr 5:7,014,383...7,071,023
Ensembl chr 5:7,008,719...7,071,025 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 5403
    chemical entity 5402
      group 5200
        inorganic group 5009
          oxo group 4787
            organic oxo compound 4787
              carbonyl compound 4787
                dicarboxylic acids and O-substituted derivatives 75
                  dicarboxylic acid 75
                    C4-dicarboxylic acid 25
                      butenedioic acid 2
                        2-amino-3-(3-oxoprop-1-enyl)but-2-enedioic acid + 0
                        3-carboxyprop-2-enoyl group + 0
                        butenedioyl group + 0
                        enol-oxaloacetic acid 0
                        fumaric acid + 0
                        maleic acid + 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 5403
    subatomic particle 5393
      composite particle 5393
        hadron 5393
          baryon 5393
            nucleon 5393
              atomic nucleus 5393
                atom 5393
                  main group element atom 5367
                    p-block element atom 5364
                      carbon group element atom 5287
                        carbon atom 5286
                          organic molecular entity 5286
                            heteroorganic entity 5135
                              organochalcogen compound 5089
                                organooxygen compound 5055
                                  carbonyl compound 4787
                                    dicarboxylic acids and O-substituted derivatives 75
                                      dicarboxylic acid 75
                                        C4-dicarboxylic acid 25
                                          butenedioic acid 2
                                            2-amino-3-(3-oxoprop-1-enyl)but-2-enedioic acid + 0
                                            3-carboxyprop-2-enoyl group + 0
                                            butenedioyl group + 0
                                            enol-oxaloacetic acid 0
                                            fumaric acid + 0
                                            maleic acid + 2
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