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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:butanone
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Accession:CHEBI:22951 term browser browse the term
Definition:Any ketone that is butane substituted by an oxo group at unspecified position.
Synonyms:related_synonym: butanones


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butan-2-one term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacng6 calcium voltage-gated channel auxiliary subunit gamma 6 decreases expression ISO methylethyl ketone results in decreased expression of CACNG6 mRNA CTD PMID:33064461 NCBI chr 1:74,648,342...74,663,351
Ensembl chr 1:74,648,063...74,662,753 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 affects response to substance ISO CYP2E1 gene mutant form affects the susceptibility to methylethyl ketone CTD PMID:21352904 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495 		JBrowse link
G Glud1 glutamate dehydrogenase 1 multiple interactions ISO
EXP 		methylethyl ketone promotes the reaction [2-dichlorobenzene results in increased activity of GLUD1 protein] CTD PMID:2554539 NCBI chr16:9,646,569...9,680,215
Ensembl chr16:9,646,509...9,680,210 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression ISO methylethyl ketone results in increased expression of PPARGC1A mRNA CTD PMID:33064461 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213 		JBrowse link
G Srsf2 serine and arginine rich splicing factor 2 decreases expression ISO methylethyl ketone results in decreased expression of SRSF2 mRNA CTD PMID:33064461 NCBI chr10:102,550,962...102,554,200
Ensembl chr10:102,553,072...102,554,141 		JBrowse link
Malabaricone C term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egfr epidermal growth factor receptor multiple interactions ISO malabaricone C promotes the reaction [Indomethacin results in increased expression of EGFR protein] CTD PMID:17977527 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions ISO malabaricone C inhibits the reaction [Indomethacin results in decreased expression of PTGS1 protein] CTD PMID:17977527 NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:39,981,415...40,002,990 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO malabaricone C inhibits the reaction [Indomethacin results in decreased expression of PTGS2 protein] CTD PMID:17977527 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20874
    chemical entity 20872
      group 20774
        inorganic group 20110
          oxo group 18827
            organic oxo compound 18827
              carbonyl compound 18827
                ketone 17484
                  butanone 8
                    (2R)-2-hydroxy-1-(8-hydroxy-3-methylisoquinolin-7-yl)-3-methylbutan-1-one 0
                    1,1-dihydroxy-3-ethoxy-2-butanone 0
                    1-(2,4-dihydroxyphenyl)heptane-1,2-dione 0
                    1-(2-naphthalenyl)hexane-1,4-dione 0
                    1-(benzo[d][1,3]dioxol-4-yl)-2-(methylamino)pentan-1-one 0
                    1-epi-paeciloketal B 0
                    3,3-dimethyl-1-(methylsulfanyl)butan-2-one 0
                    4-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-4-oxobutanoic acid 0
                    4-hydroxy-6-me~hoxy-5-(l'-oxobutyl)benzo[b]dihydrofuran 0
                    5-Dihydrobenzofuranpyrovalerone 0
                    Asperisocoumarin E 0
                    Butroxydim 0
                    Butylone 0
                    Dibutylone 0
                    Dihydronaringenin-O-sulphate 0
                    Ent-paeciloketal A 0
                    Hofmeisterin II 0
                    Malabaricone C 3
                    Marianin B 0
                    Ovalitenin B 0
                    Paeciloketal A 0
                    Paeciloketal B 0
                    Paecilospirone 0
                    Yungensin C 0
                    beta-Hydroxy-2',6'-dimethoxy-3',4'-methylenedioxydihydrochalcone 0
                    butan-2-one 5
                    florantyrone 0
                    menbutone 0
                    multifidol 0
                    multifidol glucoside 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20874
    subatomic particle 20883
      composite particle 20883
        hadron 20872
          baryon 20883
            nucleon 20872
              atomic nucleus 20883
                atom 20872
                  main group element atom 20796
                    p-block element atom 20796
                      carbon group element atom 20712
                        carbon atom 20706
                          organic molecular entity 20706
                            heteroorganic entity 20201
                              organochalcogen compound 19822
                                organooxygen compound 19713
                                  carbonyl compound 18827
                                    ketone 17484
                                      butanone 8
                                        (2R)-2-hydroxy-1-(8-hydroxy-3-methylisoquinolin-7-yl)-3-methylbutan-1-one 0
                                        1,1-dihydroxy-3-ethoxy-2-butanone 0
                                        1-(2,4-dihydroxyphenyl)heptane-1,2-dione 0
                                        1-(2-naphthalenyl)hexane-1,4-dione 0
                                        1-(benzo[d][1,3]dioxol-4-yl)-2-(methylamino)pentan-1-one 0
                                        1-epi-paeciloketal B 0
                                        3,3-dimethyl-1-(methylsulfanyl)butan-2-one 0
                                        4-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-4-oxobutanoic acid 0
                                        4-hydroxy-6-me~hoxy-5-(l'-oxobutyl)benzo[b]dihydrofuran 0
                                        5-Dihydrobenzofuranpyrovalerone 0
                                        Asperisocoumarin E 0
                                        Butroxydim 0
                                        Butylone 0
                                        Dibutylone 0
                                        Dihydronaringenin-O-sulphate 0
                                        Ent-paeciloketal A 0
                                        Hofmeisterin II 0
                                        Malabaricone C 3
                                        Marianin B 0
                                        Ovalitenin B 0
                                        Paeciloketal A 0
                                        Paeciloketal B 0
                                        Paecilospirone 0
                                        Yungensin C 0
                                        beta-Hydroxy-2',6'-dimethoxy-3',4'-methylenedioxydihydrochalcone 0
                                        butan-2-one 5
                                        florantyrone 0
                                        menbutone 0
                                        multifidol 0
                                        multifidol glucoside 0
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