Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Alpinetin
go back to main search page
Accession:CHEBI:229049 term browser browse the term
Synonyms:exact_synonym: (2S)-7-hydroxy-5-methoxy-2-phenyl-2,3-dihydrochromen-4-one
 related_synonym: Formula=C16H14O4;   InChI=1S/C16H14O4/c1-19-14-7-11(17)8-15-16(14)12(18)9-13(20-15)10-5-3-2-4-6-10/h2-8,13,17H,9H2,1H3/t13-/m0/s1;   InChIKey=QQQCWVDPMPFUGF-ZDUSSCGKSA-N;   SMILES=O1[C@@H](CC(=O)C2=C1C=C(O)C=C2OC)C3=CC=CC=C3
 xref: Chemspider:135938
 xref_mesh: MESH:C436748



show annotations for term's descendants           Sort by:
Alpinetin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions
increases activity
EXP 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [alpinetin results in increased activity of ACHE protein] CTD PMID:31034797 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO AHR protein affects the reaction [[alpinetin co-treated with TNF protein] results in decreased expression of SQSTM1 protein]; AHR protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of ATG5 mRNA]; AHR protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of ATG7 mRNA]; AHR protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of BECN1 protein]; AHR protein affects the reaction [[TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein]; AHR protein affects the reaction [[TNF protein co-treated with alpinetin] results in decreased expression of SUV39H1 protein]; AHR protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in decreased expression of TSC2 mRNA]]; AHR protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased cleavage of CASP3 protein]]; AHR protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6 protein]]; AHR protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6KB1 protein]]; AHR protein affects the reaction [alpinetin promotes the reaction [TNF protein results in increased expression of and results in increased lipidation of MAP1LC3B protein]]; alpinetin promotes the reaction [TNF promotes the reaction [AHR protein binds to SUV39H1 protein]] CTD PMID:31676321 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO ARNT protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in decreased expression of CYP1A1 protein]] CTD PMID:31676321 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
JBrowse link
G Atg5 autophagy related 5 multiple interactions ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[alpinetin co-treated with TNF protein] results in increased expression of ATG5 mRNA]; [alpinetin co-treated with TNF protein] results in increased expression of ATG5 mRNA; AHR protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of ATG5 mRNA]; TSC2 protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of ATG5 mRNA]
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin promotes the reaction [Dextran Sulfate results in increased expression of ATG5 mRNA]]; alpinetin promotes the reaction [Dextran Sulfate results in increased expression of ATG5 mRNA]; Leucine inhibits the reaction [alpinetin promotes the reaction [Dextran Sulfate results in increased expression of ATG5 mRNA]]
CTD PMID:31676321 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Atg7 autophagy related 7 multiple interactions ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[alpinetin co-treated with TNF protein] results in increased expression of ATG7 mRNA]; [alpinetin co-treated with TNF protein] results in increased expression of ATG7 mRNA; AHR protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of ATG7 mRNA]; TSC2 protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of ATG7 mRNA]
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin promotes the reaction [Dextran Sulfate results in increased expression of ATG7 mRNA]]; alpinetin promotes the reaction [Dextran Sulfate results in increased expression of ATG7 mRNA]; Leucine inhibits the reaction [alpinetin promotes the reaction [Dextran Sulfate results in increased expression of ATG7 mRNA]]
CTD PMID:31676321 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
JBrowse link
G Becn1 beclin 1 multiple interactions ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[Dextran Sulfate co-treated with alpinetin] results in increased expression of BECN1 protein]; [Dextran Sulfate co-treated with alpinetin] results in increased expression of BECN1 protein; Leucine inhibits the reaction [[Dextran Sulfate co-treated with alpinetin] results in increased expression of BECN1 protein]
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[alpinetin co-treated with TNF protein] results in increased expression of BECN1 protein]; [alpinetin co-treated with TNF protein] results in increased expression of BECN1 protein; AHR protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of BECN1 protein]; TSC2 protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of BECN1 protein]
CTD PMID:31676321 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Casp3 caspase 3 multiple interactions ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased cleavage of CASP3 protein]]; AHR protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased cleavage of CASP3 protein]]; alpinetin inhibits the reaction [TNF protein results in increased cleavage of CASP3 protein]; Chloroquine inhibits the reaction [alpinetin inhibits the reaction [TNF protein results in increased cleavage of CASP3 protein]]; TSC2 protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased cleavage of CASP3 protein]]
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [Dextran Sulfate results in increased cleavage of CASP3 protein]]; alpinetin inhibits the reaction [Dextran Sulfate results in increased cleavage of CASP3 protein]; Leucine inhibits the reaction [alpinetin inhibits the reaction [Dextran Sulfate results in increased cleavage of CASP3 protein]]
CTD PMID:31676321 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cldn7 claudin 7 multiple interactions ISO alpinetin inhibits the reaction [TNF protein results in decreased expression of CLDN7 mRNA] CTD PMID:31676321 NCBI chr10:54,689,684...54,692,177
Ensembl chr10:54,689,987...54,692,171
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO alpinetin inhibits the reaction [TNF protein results in decreased expression of CYP1A1 protein]; ARNT protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in decreased expression of CYP1A1 protein]] CTD PMID:31676321 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin promotes the reaction [TNF protein results in increased expression of and results in increased lipidation of MAP1LC3B protein]]; AHR protein affects the reaction [alpinetin promotes the reaction [TNF protein results in increased expression of and results in increased lipidation of MAP1LC3B protein]]; alpinetin promotes the reaction [TNF protein results in increased expression of and results in increased lipidation of MAP1LC3B protein]; TSC2 protein affects the reaction [alpinetin promotes the reaction [TNF protein results in increased expression of and results in increased lipidation of MAP1LC3B protein]]
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[Dextran Sulfate co-treated with alpinetin] results in increased expression of and results in increased lipidation of MAP1LC3B protein]; [Dextran Sulfate co-treated with alpinetin] results in increased expression of and results in increased lipidation of MAP1LC3B protein; Leucine inhibits the reaction [[Dextran Sulfate co-treated with alpinetin] results in increased expression of and results in increased lipidation of MAP1LC3B protein]
CTD PMID:31676321 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]]; alpinetin inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; Leucine inhibits the reaction [alpinetin inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]] CTD PMID:31676321 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Ocln occludin multiple interactions ISO alpinetin inhibits the reaction [TNF protein results in decreased expression of OCLN mRNA] CTD PMID:31676321 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
JBrowse link
G Rps6 ribosomal protein S6 multiple interactions ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6 protein]]; AHR protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6 protein]]; alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6 protein]; TSC2 protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6 protein]]
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RPS6 protein]]; alpinetin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RPS6 protein]
CTD PMID:31676321 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6KB1 protein]]; AHR protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6KB1 protein]]; alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6KB1 protein]; TSC2 protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6KB1 protein]]
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RPS6KB1 protein]]; alpinetin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RPS6KB1 protein]
CTD PMID:31676321 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[Dextran Sulfate co-treated with alpinetin] results in decreased expression of SQSTM1 protein]; [Dextran Sulfate co-treated with alpinetin] results in decreased expression of SQSTM1 protein; Leucine inhibits the reaction [[Dextran Sulfate co-treated with alpinetin] results in decreased expression of SQSTM1 protein]
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[alpinetin co-treated with TNF protein] results in decreased expression of SQSTM1 protein]; [alpinetin co-treated with TNF protein] results in decreased expression of SQSTM1 protein; AHR protein affects the reaction [[alpinetin co-treated with TNF protein] results in decreased expression of SQSTM1 protein]; TSC2 protein affects the reaction [[alpinetin co-treated with TNF protein] results in decreased expression of SQSTM1 protein]
CTD PMID:31676321 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Suv39h1 SUV39H1 histone lysine methyltransferase multiple interactions ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [Dextran Sulfate results in increased expression of SUV39H1 protein]]; alpinetin inhibits the reaction [Dextran Sulfate results in increased expression of SUV39H1 protein]
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[TNF protein co-treated with alpinetin] results in decreased expression of SUV39H1 protein]; [TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein; [TNF protein co-treated with alpinetin] results in decreased expression of SUV39H1 protein; AHR protein affects the reaction [[TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein]; AHR protein affects the reaction [[TNF protein co-treated with alpinetin] results in decreased expression of SUV39H1 protein]; alpinetin promotes the reaction [TNF promotes the reaction [AHR protein binds to SUV39H1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[TNF protein co-treated with alpinetin] results in decreased expression of SUV39H1 protein]
CTD PMID:31676321 NCBI chr  X:14,421,028...14,433,993
Ensembl chr  X:14,421,109...14,433,982
JBrowse link
G Suv39h1-ps1 SUV39H1 histone lysine methyltransferase, pseudogene 1 multiple interactions ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [Dextran Sulfate results in increased expression of SUV39H1 protein]]; alpinetin inhibits the reaction [Dextran Sulfate results in increased expression of SUV39H1 protein]
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[TNF protein co-treated with alpinetin] results in decreased expression of SUV39H1 protein]; [TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein; [TNF protein co-treated with alpinetin] results in decreased expression of SUV39H1 protein; AHR protein affects the reaction [[TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein]; AHR protein affects the reaction [[TNF protein co-treated with alpinetin] results in decreased expression of SUV39H1 protein]; alpinetin promotes the reaction [TNF promotes the reaction [AHR protein binds to SUV39H1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[TNF protein co-treated with alpinetin] results in decreased expression of SUV39H1 protein]
CTD PMID:31676321 NCBI chr  X:141,792,589...141,795,257 JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased cleavage of CASP3 protein]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[alpinetin co-treated with TNF protein] results in decreased expression of SQSTM1 protein]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[alpinetin co-treated with TNF protein] results in increased expression of ATG5 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[alpinetin co-treated with TNF protein] results in increased expression of ATG7 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[alpinetin co-treated with TNF protein] results in increased expression of BECN1 protein]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[TNF protein co-treated with alpinetin] results in decreased expression of SUV39H1 protein]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [TNF protein results in decreased expression of TSC2 mRNA]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6 protein]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6KB1 protein]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin promotes the reaction [TNF protein results in increased expression of and results in increased lipidation of MAP1LC3B protein]]; [alpinetin co-treated with TNF protein] results in decreased expression of SQSTM1 protein; [alpinetin co-treated with TNF protein] results in increased expression of ATG5 mRNA; [alpinetin co-treated with TNF protein] results in increased expression of ATG7 mRNA; [alpinetin co-treated with TNF protein] results in increased expression of BECN1 protein; [TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein; [TNF protein co-treated with alpinetin] results in decreased expression of SUV39H1 protein; AHR protein affects the reaction [[alpinetin co-treated with TNF protein] results in decreased expression of SQSTM1 protein]; AHR protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of ATG5 mRNA]; AHR protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of ATG7 mRNA]; AHR protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of BECN1 protein]; AHR protein affects the reaction [[TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein]; AHR protein affects the reaction [[TNF protein co-treated with alpinetin] results in decreased expression of SUV39H1 protein]; AHR protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in decreased expression of TSC2 mRNA]]; AHR protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased cleavage of CASP3 protein]]; AHR protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6 protein]]; AHR protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6KB1 protein]]; AHR protein affects the reaction [alpinetin promotes the reaction [TNF protein results in increased expression of and results in increased lipidation of MAP1LC3B protein]]; alpinetin inhibits the reaction [TNF protein results in decreased expression of CLDN7 mRNA]; alpinetin inhibits the reaction [TNF protein results in decreased expression of CYP1A1 protein]; alpinetin inhibits the reaction [TNF protein results in decreased expression of OCLN mRNA]; alpinetin inhibits the reaction [TNF protein results in decreased expression of TSC2 mRNA]; alpinetin inhibits the reaction [TNF protein results in decreased expression of TSC2 protein]; alpinetin inhibits the reaction [TNF protein results in increased cleavage of CASP3 protein]; alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6 protein]; alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6KB1 protein]; alpinetin promotes the reaction [TNF promotes the reaction [AHR protein binds to SUV39H1 protein]]; alpinetin promotes the reaction [TNF protein results in increased expression of and results in increased lipidation of MAP1LC3B protein]; ARNT protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in decreased expression of CYP1A1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[TNF protein co-treated with alpinetin] results in decreased expression of SUV39H1 protein]; Chloroquine inhibits the reaction [alpinetin inhibits the reaction [TNF protein results in increased cleavage of CASP3 protein]]; TSC2 protein affects the reaction [[alpinetin co-treated with TNF protein] results in decreased expression of SQSTM1 protein]; TSC2 protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of ATG5 mRNA]; TSC2 protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of ATG7 mRNA]; TSC2 protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of BECN1 protein]; TSC2 protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased cleavage of CASP3 protein]]; TSC2 protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6 protein]]; TSC2 protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6KB1 protein]]; TSC2 protein affects the reaction [alpinetin promotes the reaction [TNF protein results in increased expression of and results in increased lipidation of MAP1LC3B protein]] CTD PMID:31676321 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tsc2 TSC complex subunit 2 multiple interactions ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [TNF protein results in decreased expression of TSC2 mRNA]]; AHR protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in decreased expression of TSC2 mRNA]]; alpinetin inhibits the reaction [TNF protein results in decreased expression of TSC2 mRNA]; alpinetin inhibits the reaction [TNF protein results in decreased expression of TSC2 protein]; TSC2 protein affects the reaction [[alpinetin co-treated with TNF protein] results in decreased expression of SQSTM1 protein]; TSC2 protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of ATG5 mRNA]; TSC2 protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of ATG7 mRNA]; TSC2 protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of BECN1 protein]; TSC2 protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased cleavage of CASP3 protein]]; TSC2 protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6 protein]]; TSC2 protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6KB1 protein]]; TSC2 protein affects the reaction [alpinetin promotes the reaction [TNF protein results in increased expression of and results in increased lipidation of MAP1LC3B protein]]
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [Dextran Sulfate results in decreased expression of TSC2 protein]]; alpinetin inhibits the reaction [Dextran Sulfate results in decreased expression of TSC2 protein]
CTD PMID:31676321 NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19915
    chemical entity 19913
      atom 19895
        nonmetal atom 19817
          carbon atom 19770
            organic molecular entity 19770
              flavonoids 11632
                Alpinetin 19
Path 2
Term Annotations click to browse term
  CHEBI ontology 19915
    subatomic particle 19913
      composite particle 19895
        hadron 19895
          baryon 19913
            nucleon 19895
              atomic nucleus 19913
                atom 19895
                  main group element atom 19852
                    p-block element atom 19834
                      carbon group element atom 19774
                        carbon atom 19770
                          organic molecular entity 19770
                            heteroorganic entity 19542
                              organochalcogen compound 19302
                                organooxygen compound 19218
                                  ether 17325
                                    Alpinetin 19
paths to the root