CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: Sophocarpine
Accession: CHEBI:228910
browse the term
Synonyms: exact_synonym: (1R,2R,9S,17S)-7,13-diazatetracyclo[7.7.1.02,7.013,17]heptadec-4-en-6-one
related_synonym: Formula=C15H22N2O; InChI=1S/C15H22N2O/c18-14-7-1-6-13-12-5-3-9-16-8-2-4-11(15(12)16)10-17(13)14/h1,7,11-13,15H,2-6,8-10H2/t11-,12+,13+,15-/m0/s1; InChIKey=AAGFPTSOPGCENQ-JLNYLFASSA-N; SMILES=O=C1N2[C@@]([C@@]3([C@]4(N(CCC3)CCC[C@]4(C2)[H])[H])[H])(CC=C1)[H]
xref: Chemspider:103136
xref_mesh: MESH:C035933
G
Adipoq
adiponectin, C1Q and collagen domain containing
multiple interactions
EXP
sophocarpine inhibits the reaction [Oleic Acid results in decreased expression of ADIPOQ mRNA]
CTD
PMID:23395669
NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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Hnf4a
hepatocyte nuclear factor 4, alpha
multiple interactions
EXP
sophocarpine inhibits the reaction [Oleic Acid results in increased expression of HNF4A protein]
CTD
PMID:23395669
NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
G
Il6
interleukin 6
multiple interactions
ISO
sophocarpine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
CTD
PMID:21978812
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Lep
leptin
multiple interactions
EXP
sophocarpine inhibits the reaction [Oleic Acid results in increased expression of LEP mRNA]
CTD
PMID:23395669
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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Nfkbia
NFKB inhibitor alpha
multiple interactions
ISO
sophocarpine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]
CTD
PMID:21978812
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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Nos2
nitric oxide synthase 2
multiple interactions
ISO
sophocarpine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
CTD
PMID:21978812
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions
ISO
sophocarpine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]
CTD
PMID:21978812
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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Srebf1
sterol regulatory element binding transcription factor 1
multiple interactions
EXP
sophocarpine inhibits the reaction [Oleic Acid results in increased expression of SREBF1 mRNA]
CTD
PMID:23395669
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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Tnf
tumor necrosis factor
multiple interactions
ISO
sophocarpine inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
CTD
PMID:21978812
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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