Harpagide - Ontology Report - Rat Genome Database

[harpagide co-treated with AGT protein] results in increased expression of MRC1 protein; harpagide inhibits the reaction [AGT protein affects the localization of RELA protein]; harpagide inhibits the reaction [AGT protein results in decreased expression of TREM2 protein]; harpagide inhibits the reaction [AGT protein results in increased expression of and results in increased secretion of IL1B protein]; harpagide inhibits the reaction [AGT protein results in increased expression of and results in increased secretion of IL6 protein]; harpagide inhibits the reaction [AGT protein results in increased expression of and results in increased secretion of TNF protein]; harpagide inhibits the reaction [AGT protein results in increased expression of CD86 protein]; harpagide inhibits the reaction [AGT protein results in increased expression of MYD88 protein]; harpagide inhibits the reaction [AGT protein results in increased expression of NOS2 protein]; harpagide inhibits the reaction [AGT protein results in increased expression of TLR4 protein]

NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977

Cd86

CD86 molecule

multiple interactions

harpagide inhibits the reaction [AGT protein results in increased expression of CD86 protein]; harpagide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CD86 protein]

NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818

Il1b

interleukin 1 beta

multiple interactions

harpagide inhibits the reaction [AGT protein results in increased expression of and results in increased secretion of IL1B protein]; harpagide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL1B protein]

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

Il6

interleukin 6

multiple interactions

harpagide inhibits the reaction [AGT protein results in increased expression of and results in increased secretion of IL6 protein]; harpagide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 protein]

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

Mrc1

mannose receptor, C type 1

multiple interactions

[harpagide co-treated with AGT protein] results in increased expression of MRC1 protein

NCBI chr17:77,249,187...77,330,857
Ensembl chr17:77,249,187...77,330,857

Myd88

MYD88, innate immune signal transduction adaptor

multiple interactions

harpagide inhibits the reaction [AGT protein results in increased expression of MYD88 protein]; harpagide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of MYD88 protein]

NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415

Nos2

nitric oxide synthase 2

multiple interactions

harpagide inhibits the reaction [AGT protein results in increased expression of NOS2 protein]; harpagide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 protein]

NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210

Rela

RELA proto-oncogene, NF-kB subunit

multiple interactions

harpagide inhibits the reaction [AGT protein affects the localization of RELA protein]; harpagide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the localization of RELA protein]

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

Tlr4

toll-like receptor 4

multiple interactions

harpagide inhibits the reaction [AGT protein results in increased expression of TLR4 protein]; harpagide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TLR4 protein]

NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628

Tnf

tumor necrosis factor

multiple interactions

harpagide inhibits the reaction [AGT protein results in increased expression of and results in increased secretion of TNF protein]; harpagide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF protein]

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

Trem2

triggering receptor expressed on myeloid cells 2

multiple interactions

harpagide inhibits the reaction [AGT protein results in decreased expression of TREM2 protein]; harpagide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of TREM2 protein]