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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:betalain
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Accession:CHEBI:22861 term browser browse the term
Definition:Any of a group of coloured alkaloids occurring widely in plants of the order Centrospermae. They are divided into two groups, betacyanins and betaxanthins, and both occur in plant vacuoles.
Synonyms:related_synonym: betalains
 xref: CAS:37279-84-8
 xref_mesh: MESH:D050858


show annotations for term's descendants           Sort by:
betalain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor decreases expression ISO Betalains results in decreased expression of AHR protein CTD PMID:33522684 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases expression ISO Betalains results in decreased expression of AKT1 mRNA CTD PMID:33522684 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Betalains results in decreased expression of CCND1 mRNA CTD PMID:33522684 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Betalains results in increased expression of CDKN1A mRNA CTD PMID:33522684 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Il1b interleukin 1 beta decreases expression ISO Betalains results in decreased expression of IL1B protein CTD PMID:33522684 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 decreases expression ISO Betalains results in decreased expression of IL6 protein CTD PMID:33522684 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases expression ISO Betalains results in decreased expression of MTOR mRNA CTD PMID:33522684 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Nt5e 5' nucleotidase, ecto decreases expression ISO Betalains results in decreased expression of NT5E protein CTD PMID:33522684 NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:89,270,696...89,314,881 		JBrowse link
G Tnf tumor necrosis factor decreases expression ISO Betalains results in decreased expression of TNF protein CTD PMID:33522684 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tp53 tumor protein p53 increases expression ISO Betalains results in increased expression of TP53 mRNA CTD PMID:33522684 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
Betanin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions EXP betanin inhibits the reaction [Cytarabine results in increased activity of ACHE protein] CTD PMID:36419121 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases expression ISO betanin results in decreased expression of AKT1 protein CTD PMID:37401526 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [betanin inhibits the reaction [Cisplatin results in increased expression of BAX protein]]; betanin inhibits the reaction [Cisplatin results in increased expression of BAX protein] CTD PMID:33661552 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bche butyrylcholinesterase multiple interactions EXP betanin inhibits the reaction [Cytarabine results in increased activity of BCHE protein] CTD PMID:36419121 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [betanin inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein]]; betanin inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein] CTD PMID:33661552 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Cat catalase multiple interactions EXP betanin inhibits the reaction [Paraquat results in decreased activity of CAT protein] CTD PMID:24799198 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions EXP betanin inhibits the reaction [Fructose results in increased expression of CCN2 protein] CTD PMID:25559852 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions EXP betanin inhibits the reaction [Paraquat results in increased expression of CYP3A2 mRNA] CTD PMID:24799198 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions EXP 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [betanin inhibits the reaction [Cisplatin results in decreased expression of GCLM mRNA]]; betanin inhibits the reaction [Cisplatin results in decreased expression of GCLM mRNA] CTD PMID:33661552 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [betanin inhibits the reaction [Cisplatin results in increased expression of GPT protein]]; betanin inhibits the reaction [Cisplatin results in increased expression of GPT protein] CTD PMID:33661552 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Ins1 insulin 1 multiple interactions EXP betanin inhibits the reaction [Fructose results in increased expression of INS1 protein] CTD PMID:25559852 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536 		JBrowse link
G Mir34a microRNA 34a multiple interactions EXP betanin inhibits the reaction [Cisplatin results in increased expression of MIR34A mRNA] CTD PMID:33661552 NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103 		JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases expression ISO betanin results in decreased expression of MTOR protein CTD PMID:37401526 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [betanin inhibits the reaction [Cisplatin results in decreased expression of and affects the localization of NFE2L2 protein]]; betanin inhibits the reaction [Cisplatin results in decreased expression of and affects the localization of NFE2L2 protein] CTD PMID:33661552 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions EXP 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [betanin inhibits the reaction [Cisplatin results in decreased expression of PPARGC1A mRNA]]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [betanin inhibits the reaction [Cisplatin results in increased acetylation of PPARGC1A protein]]; betanin inhibits the reaction [Cisplatin results in decreased expression of PPARGC1A mRNA]; betanin inhibits the reaction [Cisplatin results in increased acetylation of PPARGC1A protein] CTD PMID:33661552 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Rps6 ribosomal protein S6 decreases expression ISO betanin results in decreased expression of RPS6 protein CTD PMID:37401526 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602 		JBrowse link
G Sirt1 sirtuin 1 multiple interactions EXP 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [betanin inhibits the reaction [Cisplatin results in decreased activity of SIRT1 protein]]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [betanin inhibits the reaction [Cisplatin results in decreased expression of SIRT1 mRNA]]; betanin inhibits the reaction [Cisplatin results in decreased activity of SIRT1 protein]; betanin inhibits the reaction [Cisplatin results in decreased expression of SIRT1 mRNA] CTD PMID:33661552 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP betanin inhibits the reaction [Fructose results in increased expression of TGFB1 protein] CTD PMID:25559852 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19867
    role 19837
      biological role 19835
        biochemical role 19552
          metabolite 19539
            alkaloid 8020
              betalain 26
                Betanin 18
                Bougainvillein-r-I 0
                Celosianin II 0
                Iresinin I 0
                Isobetanin 0
                Lampranthin II 0
                Prebetanin 0
                betalamic acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19867
    subatomic particle 19865
      composite particle 19865
        hadron 19865
          baryon 19865
            nucleon 19865
              atomic nucleus 19865
                atom 19865
                  main group element atom 19803
                    main group molecular entity 19803
                      p-block molecular entity 19803
                        carbon group molecular entity 19744
                          organic molecular entity 19740
                            heteroorganic entity 19512
                              organonitrogen compound 18832
                                alkaloid 8020
                                  betalain 26
                                    Betanin 18
                                    Bougainvillein-r-I 0
                                    Celosianin II 0
                                    Iresinin I 0
                                    Isobetanin 0
                                    Lampranthin II 0
                                    Prebetanin 0
                                    betalamic acid 0
paths to the root