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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:MJN110
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Accession:CHEBI:228388 term browser browse the term
Synonyms:exact_synonym: (2,5-dioxopyrrolidin-1-yl) 4-[bis(4-chlorophenyl)methyl]piperazine-1-carboxylate
 related_synonym: Formula=C22H21Cl2N3O4;   InChI=1S/C22H21Cl2N3O4/c23-17-5-1-15(2-6-17)21(16-3-7-18(24)8-4-16)25-11-13-26(14-12-25)22(30)31-27-19(28)9-10-20(27)29/h1-8,21H,9-14H2;   InChIKey=BEADRWVIFHOSGN-UHFFFAOYSA-N;   SMILES=ClC1=CC=C(C(N2CCN(CC2)C(ON3C(=O)CCC3=O)=O)C4=CC=C(Cl)C=C4)C=C1
 xref: Chemspider:34975859;   HMDB:HMDB0254772;   KEGG:D81272
 xref_mesh: MESH:C587715


show annotations for term's descendants           Sort by:
MJN110 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg5 autophagy related 5 multiple interactions ISO ATG5 protein affects the reaction [MJN110 affects the reaction [Lipopolysaccharides affects the secretion of CCL2 protein]]; ATG5 protein affects the reaction [MJN110 affects the reaction [Lipopolysaccharides affects the secretion of IL1A protein]]; ATG5 protein affects the reaction [MJN110 affects the reaction [Lipopolysaccharides affects the secretion of IL1B protein]]; ATG5 protein affects the reaction [MJN110 affects the reaction [Lipopolysaccharides affects the secretion of IL6 protein]] CTD PMID:30301768 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO ATG5 protein affects the reaction [MJN110 affects the reaction [Lipopolysaccharides affects the secretion of CCL2 protein]]; MJN110 affects the reaction [Lipopolysaccharides affects the secretion of CCL2 protein] CTD PMID:30301768 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO ATG5 protein affects the reaction [MJN110 affects the reaction [Lipopolysaccharides affects the secretion of IL1A protein]]; MJN110 affects the reaction [Lipopolysaccharides affects the secretion of IL1A protein] CTD PMID:30301768 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO ATG5 protein affects the reaction [MJN110 affects the reaction [Lipopolysaccharides affects the secretion of IL1B protein]]; MJN110 affects the reaction [Lipopolysaccharides affects the secretion of IL1B protein] CTD PMID:30301768 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO ATG5 protein affects the reaction [MJN110 affects the reaction [Lipopolysaccharides affects the secretion of IL6 protein]]; MJN110 affects the reaction [Lipopolysaccharides affects the secretion of IL6 protein] CTD PMID:30301768 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions
increases lipidation		 ISO MJN110 affects the reaction [Chloroquine results in increased lipidation of MAP1LC3B protein]
MJN110 results in increased lipidation of MAP1LC3B protein		 CTD PMID:30301768 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 		JBrowse link
G Mgll monoglyceride lipase multiple interactions
decreases activity		 ISO [MJN110 results in decreased activity of MGLL protein] which results in decreased hydrolysis of and results in increased abundance of glyceryl 2-arachidonate CTD PMID:26791602 PMID:27307500 NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19911
    chemical entity 19909
      group 19863
        polyatomic entity 19862
          molecule 19752
            cyclic compound 19523
              organic cyclic compound 19526
                organic aromatic compound 19390
                  diarylmethane 9440
                    MJN110 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19911
    subatomic particle 19909
      composite particle 19909
        hadron 19880
          baryon 19880
            nucleon 19909
              atomic nucleus 19880
                atom 19909
                  main group element atom 19849
                    p-block element atom 19849
                      p-block molecular entity 19826
                        carbon group molecular entity 19766
                          organic molecular entity 19785
                            organic molecule 19737
                              organic cyclic compound 19526
                                organic aromatic compound 19390
                                  diarylmethane 9440
                                    MJN110 7
paths to the root