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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:alpha-terpineol
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Accession:CHEBI:22469 term browser browse the term
Definition:A terpineol that is propan-2-ol substituted by a 4-methylcyclohex-3-en-1-yl group at position 2.
Synonyms:related_synonym: (+)-p-menth-1-en-8-ol;   1-alpha-terpineol;   1-menthene-8-ol;   1-methyl-4-isopropyl-1-cyclohexen-8-ol;   1-methyl-4-isopropyl-1-cyclohexene-8-ol;   2-(4-Methylcyclohex-3-en-1-yl)propan-2-ol;   2-(4-methyl-3-cyclohexenyl)-2-propanol;   Formula=C10H18O;   InChI=1S/C10H18O/c1-8-4-6-9(7-5-8)10(2,3)11/h4,9,11H,5-7H2,1-3H3;   InChIKey=WUOACPNHFRMFPN-UHFFFAOYSA-N;   SMILES=CC1=CCC(CC1)C(C)(C)O;   alpha,alpha,4-trimethyl-3-cyclohexene-1-methanol
 xref: BPDB:2015;   CAS:98-55-5;   Gmelin:406992;   HMDB:HMDB0004043;   KEGG:C16772;   KNApSAcK:C00029674
 xref_mesh: MESH:C016775
 xref: PMID:16356517;   Reaxys:1906604;   UM-BBD_compID:c0669


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alpha-terpineol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsd cathepsin D increases expression ISO alpha-terpineol results in increased expression of CTSD mRNA CTD PMID:31393563 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488 		JBrowse link
G Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 multiple interactions ISO alpha-terpineol inhibits the reaction [Testosterone results in increased expression of CYP4F8 mRNA] CTD PMID:31393563 NCBI chr 7:12,030,276...12,058,020
Ensembl chr 7:12,030,301...12,057,782 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
increases activity		 ISO alpha-terpineol binds to and results in increased activity of ESR1 protein; NCOA2 protein promotes the reaction [alpha-terpineol results in increased activity of ESR1 protein] CTD PMID:27633901 PMID:31393563 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 multiple interactions
increases expression		 ISO Fulvestrant inhibits the reaction [alpha-terpineol results in increased expression of GREB1 mRNA] CTD PMID:31393563 NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633 		JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO NCOA2 protein promotes the reaction [alpha-terpineol results in increased activity of ESR1 protein] CTD PMID:31393563 NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451 		JBrowse link
G Sec14l2 SEC14-like lipid binding 2 multiple interactions ISO alpha-terpineol inhibits the reaction [Testosterone results in increased expression of SEC14L2 mRNA] CTD PMID:31393563 NCBI chr14:78,973,805...78,998,480
Ensembl chr14:78,973,808...78,993,788 		JBrowse link
G Ugt2b15 UDP glucuronosyltransferase family 2 member B15 increases metabolic processing EXP UGT2B15 protein results in increased metabolism of alpha-terpineol CTD PMID:7574722 NCBI chr14:20,768,015...20,783,599
Ensembl chr14:20,768,015...20,783,589 		JBrowse link
G Ugt2b34l1 UDP glucuronosyltransferase 2 family, polypeptide B34 like 1 multiple interactions ISO alpha-terpineol inhibits the reaction [Testosterone results in increased expression of UGT2B28 mRNA] CTD PMID:31393563 NCBI chr14:21,146,140...21,167,706
Ensembl chr14:21,145,827...21,167,704 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    role 19850
      biological role 19848
        biochemical role 19556
          metabolite 19544
            eukaryotic metabolite 19368
              plant metabolite 17985
                alpha-terpineol 8
                  (R)-(+)-alpha-terpineol 0
                  (S)-(-)-alpha-terpineol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    main group molecular entity 19817
                      s-block molecular entity 19653
                        hydrogen molecular entity 19634
                          hydrides 19144
                            organic hydride 18691
                              organic fundamental parent 18691
                                hydrocarbon 18442
                                  terpene 14066
                                    terpenoid 13765
                                      monoterpenoid 2042
                                        p-menthane monoterpenoid 487
                                          terpineol 10
                                            alpha-terpineol 8
                                              (R)-(+)-alpha-terpineol 0
                                              (S)-(-)-alpha-terpineol 0
paths to the root