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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:N-acetyl-L-methionine
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Accession:CHEBI:21557 term browser browse the term
Definition:An L-methionine derivative that is L-methionine in which one of the amine hydrogens is substituted by an acetyl group.
Synonyms:related_synonym: (2S)-2-acetamido-4-(methylsulfanyl)butanoic acid;   AcMet;   Acetyl-L-methionine;   Acetylmethionine;   Formula=C7H13NO3S;   InChI=1S/C7H13NO3S/c1-5(9)8-6(7(10)11)3-4-12-2/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)/t6-/m0/s1;   InChIKey=XUYPXLNMDZIRQH-LURJTMIESA-N;   Methionamine;   N-Ac-Met;   N-Acetylmethionine;   Nalpha-acetyl-L-methionine;   SMILES=CSCC[C@H](NC(C)=O)C(O)=O
 alt_id: CHEBI:40767
 xref: CAS:65-82-7;   DrugBank:DB01646;   HMDB:HMDB0011745;   KEGG:C02712
 xref_mesh: MESH:C006379
 xref: MetaCyc:CPD0-2015;   PDBeChem:AME;   PMID:16091934;   PMID:16129491;   PMID:21246718;   PMID:21796695;   PMID:24769178;   PMID:448454;   PMID:7069504;   PMID:7354384;   PMID:845673;   PMID:986424;   Reaxys:1725552;   Reaxys:4744969
 cyclic_relationship: is_conjugate_acid_of CHEBI:71670;   is_enantiomer_of CHEBI:85210


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N-acetyl-L-methionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Glud1 glutamate dehydrogenase 1 decreases activity EXP N-acetylmethionine results in decreased activity of GLUD1 protein CTD PMID:37871522 NCBI chr16:9,646,569...9,680,215
Ensembl chr16:9,646,509...9,680,210 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    role 20820
      application 20621
        pharmaceutical 20416
          drug 20416
            nutraceutical 13882
              N-acetyl-L-methionine 1
                N-acetyl-DL-methionine 0
                N-acetyl-L-methionine sulfone 0
                N-acetyl-L-methionyl residue 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    p-block element atom 20781
                      carbon group element atom 20715
                        carbon atom 20710
                          organic molecular entity 20710
                            heteroorganic entity 20219
                              organochalcogen compound 19904
                                organooxygen compound 19806
                                  carbon oxoacid 19155
                                    carboxylic acid 19152
                                      monocarboxylic acid 18309
                                        fatty acid 17010
                                          straight-chain fatty acid 16211
                                            straight-chain saturated fatty acid 16211
                                              butyric acid 6785
                                                methionine 3553
                                                  methionine derivative 69
                                                    L-methionine derivative 62
                                                      N-acetyl-L-methionine 1
                                                        N-acetyl-DL-methionine 0
                                                        N-acetyl-L-methionine sulfone 0
                                                        N-acetyl-L-methionyl residue 0
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