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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:4-chloroaniline
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Accession:CHEBI:20331 term browser browse the term
Definition:A chloroaniline in which the chloro atom is para to the aniline amino group.
Synonyms:related_synonym: 4-Amino-1-chlorobenzene;   4-Chloro-phenylamine;   4-Chlorobenzenamine;   Formula=C6H6ClN;   InChI=1S/C6H6ClN/c7-5-1-3-6(8)4-2-5/h1-4H,8H2;   InChIKey=QSNSCYSYFYORTR-UHFFFAOYSA-N;   SMILES=Nc1ccc(Cl)cc1;   p-Chloroaniline;   para-Chloroaniline
 alt_id: CHEBI:116809;   CHEBI:34397
 xref: CAS:106-47-8;   KEGG:C14450
 xref_mesh: MESH:C004658
 xref: PMID:10848923;   PMID:24038698;   Reaxys:471359;   UM-BBD_compID:c0766;   Wikipedia:4-Chloroaniline


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4-chloroaniline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G H2ax H2A.X variant histone increases phosphorylation ISO 4-chloroaniline results in increased phosphorylation of H2AX protein CTD PMID:34510228 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
Ensembl chr 4:44,671,786...44,673,239 		JBrowse link
G Mpo myeloperoxidase multiple interactions ISO [[MPO protein co-treated with Hydrogen Peroxide co-treated with 5,5-dimethyl-1-pyrroline-1-oxide] results in increased metabolism of 4-chloroaniline] which results in increased expression of MPO protein modified form; [MPO protein co-treated with Hydrogen Peroxide co-treated with 5,5-dimethyl-1-pyrroline-1-oxide] results in increased metabolism of 4-chloroaniline CTD PMID:20199096 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Nat1 N-acetyltransferase 1 increases acetylation ISO NAT1 protein results in increased acetylation of 4-chloroaniline CTD PMID:15627487 NCBI chr16:22,218,217...22,238,516
Ensembl chr16:22,208,194...22,238,520 		JBrowse link
G Nat2 N-acetyltransferase 2 increases acetylation ISO NAT2 protein results in increased acetylation of 4-chloroaniline CTD PMID:15627487 NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520 		JBrowse link
G Tp53 tumor protein p53 affects expression ISO 4-chloroaniline affects the expression of TP53 mRNA CTD PMID:27825931 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    chemical entity 19872
      molecular entity 19872
        polyatomic entity 19824
          heteroatomic molecular entity 19781
            halide 18659
              organohalogen compound 18523
                organochlorine compound 18295
                  chlorobenzenes 15043
                    chloroaniline 233
                      4-chloroaniline 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    main group molecular entity 19811
                      s-block molecular entity 19647
                        hydrogen molecular entity 19628
                          hydrides 19139
                            inorganic hydride 18156
                              pnictogen hydride 18146
                                nitrogen hydride 18059
                                  azane 17866
                                    ammonia 17865
                                      organic amino compound 17865
                                        aromatic amine 15478
                                          anilines 14416
                                            substituted aniline 14046
                                              chloroaniline 233
                                                4-chloroaniline 5
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