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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:5,6-dihydroxyindole-2-carboxylic acid
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Accession:CHEBI:2003 term browser browse the term
Definition:A dihydroxyindole that is indole-2-carboxylic acid substituted by hydroxy groups at positions 5 and 6.
Synonyms:exact_synonym: 5,6-dihydroxy-1H-indole-2-carboxylic acid
 related_synonym: 5,6-DHICA;   5,6-Dihydroxyindole-2-carboxylate;   5,6-dihydroxy-2-indolecarboxylic acid;   5,6-dihydroxy-2-indolylcarboxylic acid;   DHI2C;   DHICA;   Formula=C9H7NO4;   InChI=1S/C9H7NO4/c11-7-2-4-1-6(9(13)14)10-5(4)3-8(7)12/h1-3,10-12H,(H,13,14);   InChIKey=YFTGOBNOJKXZJC-UHFFFAOYSA-N;   SMILES=OC(=O)C1=CC2=CC(O)=C(O)C=C2N1
 xref: Beilstein:168167;   CAS:4790-08-3;   KEGG:C04185
 xref_mesh: MESH:C030692
 xref: PMID:25450182;   Reaxys:168167
 cyclic_relationship: is_conjugate_acid_of CHEBI:16875;   is_tautomer_of CHEBI:49108


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5,6-dihydroxyindole-2-carboxylic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dct dopachrome tautomerase decreases abundance ISO DCT gene mutant form results in decreased abundance of 5,6-dihydroxy-2-indolylcarboxylic acid CTD PMID:11277491 NCBI chr15:95,062,006...95,100,863
Ensembl chr15:95,062,003...95,100,836 		JBrowse link
G Oca2 OCA2 melanosomal transmembrane protein decreases abundance ISO OCA2 gene mutant form results in decreased abundance of 5,6-dihydroxy-2-indolylcarboxylic acid CTD PMID:12064459 NCBI chr 1:107,116,278...107,446,093
Ensembl chr 1:107,116,278...107,446,074 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19917
    chemical entity 19915
      molecular entity 19915
        polyatomic entity 19868
          heteroatomic molecular entity 19826
            hydroxides 19380
              organic hydroxy compound 18988
                hydroxyindoles 175
                  dihydroxyindole 2
                    5,6-dihydroxyindole-2-carboxylic acid 2
                      indole-5,6-quinone-2-carboxylic acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19917
    subatomic particle 19915
      composite particle 19915
        hadron 19915
          baryon 19915
            nucleon 19915
              atomic nucleus 19915
                atom 19915
                  main group element atom 19855
                    p-block element atom 19855
                      carbon group element atom 19774
                        carbon atom 19790
                          organic molecular entity 19790
                            organic molecule 19743
                              organic cyclic compound 19533
                                organic heterocyclic compound 18903
                                  organic heteropolycyclic compound 18317
                                    organic heterobicyclic compound 17257
                                      benzopyrrole 9739
                                        indoles 9426
                                          hydroxyindoles 175
                                            dihydroxyindole 2
                                              5,6-dihydroxyindole-2-carboxylic acid 2
                                                indole-5,6-quinone-2-carboxylic acid 0
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