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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:medium-chain fatty alcohol
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Accession:CHEBI:197506 term browser browse the term
Definition:Any fatty alcohol with a chain length between C6 and C12.
Synonyms:related_synonym: medium-chain fatty alcohols


show annotations for term's descendants           Sort by:
3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc3 ATP binding cassette subfamily C member 3 increases expression EXP fluorotelomer alcohols results in increased expression of ABCC3 mRNA CTD PMID:38903859 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 decreases expression EXP fluorotelomer alcohols results in decreased expression of ABCG5 mRNA CTD PMID:38903859 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563 		JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 increases expression EXP fluorotelomer alcohols results in increased expression of ACAT1 mRNA CTD PMID:38903859 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855 		JBrowse link
G Acox1 acyl-CoA oxidase 1 increases expression EXP fluorotelomer alcohols results in increased expression of ACOX1 mRNA CTD PMID:38903859 NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232 		JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 increases expression EXP fluorotelomer alcohols results in increased expression of ACSL1 mRNA CTD PMID:38903859 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541 		JBrowse link
G Angptl4 angiopoietin-like 4 increases expression EXP fluorotelomer alcohols results in increased expression of ANGPTL4 mRNA CTD PMID:38903859 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519 		JBrowse link
G Ccna1 cyclin A1 decreases expression ISO fluorotelomer alcohols results in decreased expression of CCNA1 mRNA CTD PMID:30794351 NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157 		JBrowse link
G Ccna2 cyclin A2 decreases expression ISO fluorotelomer alcohols results in decreased expression of CCNA2 mRNA CTD PMID:30794351 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO fluorotelomer alcohols results in decreased expression of CCND1 mRNA CTD PMID:30794351 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccne2 cyclin E2 decreases expression ISO fluorotelomer alcohols results in decreased expression of CCNE2 mRNA CTD PMID:30794351 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression EXP fluorotelomer alcohols results in decreased expression of CDKN1A mRNA CTD PMID:38903859 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cebpe CCAAT/enhancer binding protein epsilon decreases expression ISO fluorotelomer alcohols results in decreased expression of CEBPE mRNA CTD PMID:30794351 NCBI chr15:28,169,711...28,171,471
Ensembl chr15:28,169,704...28,171,814 		JBrowse link
G Csf3r colony stimulating factor 3 receptor decreases expression ISO fluorotelomer alcohols results in decreased expression of CSF3R mRNA CTD PMID:30794351 NCBI chr 5:138,298,605...138,318,224
Ensembl chr 5:138,301,506...138,317,881 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression ISO fluorotelomer alcohols results in decreased expression of CXCL1 mRNA CTD PMID:30536526 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression ISO fluorotelomer alcohols results in decreased expression of CYP11A1 mRNA; fluorotelomer alcohols results in decreased expression of CYP11A1 protein CTD PMID:20615422 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 decreases expression ISO fluorotelomer alcohols results in decreased expression of CYP11B1 mRNA; fluorotelomer alcohols results in decreased expression of CYP11B1 protein CTD PMID:20615422 NCBI chr 7:106,838,590...106,845,004
Ensembl chr 7:106,838,590...106,845,004 		JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 decreases expression ISO fluorotelomer alcohols results in decreased expression of CYP11B2 mRNA; fluorotelomer alcohols results in decreased expression of CYP11B2 protein CTD PMID:20615422 NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression ISO fluorotelomer alcohols results in decreased expression of CYP17A1 mRNA; fluorotelomer alcohols results in decreased expression of CYP17A1 protein CTD PMID:20615422 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases expression ISO fluorotelomer alcohols results in increased expression of CYP19A1 mRNA CTD PMID:23142464 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases expression EXP fluorotelomer alcohols results in decreased expression of CYP1A2 mRNA CTD PMID:38903859 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity ISO fluorotelomer alcohols results in decreased activity of CYP2E1 protein CTD PMID:35121066 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 affects expression EXP fluorotelomer alcohols affects the expression of CYP7A1 mRNA CTD PMID:38903859 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 decreases expression ISO fluorotelomer alcohols results in decreased expression of ERBB2 mRNA CTD PMID:16393665 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Esr1 estrogen receptor 1 increases activity
increases expression
multiple interactions		 ISO fluorotelomer alcohols results in increased activity of ESR1 protein
fluorotelomer alcohols results in increased expression of ESR1 mRNA
fluorotelomer alcohols promotes the reaction [ESR1 protein binds to NCOA2 protein]		 CTD PMID:16393665 PMID:17603182 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
increases activity		 ISO fluorotelomer alcohols promotes the reaction [ESR2 protein binds to NCOA2 protein]
fluorotelomer alcohols results in increased activity of ESR2 protein		 CTD PMID:17603182 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G G0s2 G0/G1switch 2 affects expression EXP fluorotelomer alcohols affects the expression of G0S2 mRNA CTD PMID:38903859 NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451 		JBrowse link
G Ifng interferon gamma multiple interactions ISO fluorotelomer alcohols inhibits the reaction [Mitogens results in increased secretion of IFNG protein] CTD PMID:30536526 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 affects expression EXP fluorotelomer alcohols affects the expression of IGFBP1 mRNA CTD PMID:38903859 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 decreases expression EXP fluorotelomer alcohols results in decreased expression of IGFBP3 mRNA CTD PMID:38903859 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
affects expression		 ISO fluorotelomer alcohols results in decreased expression of and results in decreased secretion of IL1B protein
fluorotelomer alcohols affects the expression of IL1B mRNA		 CTD PMID:30536526 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 decreases expression ISO fluorotelomer alcohols results in decreased expression of IL6 mRNA CTD PMID:30536526 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Itgam integrin subunit alpha M decreases expression ISO fluorotelomer alcohols results in decreased expression of ITGAM mRNA CTD PMID:30794351 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Mfsd2a MFSD2 lysolipid transporter A, lysophospholipid decreases expression EXP fluorotelomer alcohols results in decreased expression of MFSD2A mRNA CTD PMID:38903859 NCBI chr 5:135,225,801...135,240,744
Ensembl chr 5:135,225,816...135,240,690 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor affects expression EXP fluorotelomer alcohols affects the expression of MYC mRNA CTD PMID:38903859 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO fluorotelomer alcohols promotes the reaction [ESR1 protein binds to NCOA2 protein]; fluorotelomer alcohols promotes the reaction [ESR2 protein binds to NCOA2 protein] CTD PMID:17603182 NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression EXP fluorotelomer alcohols results in increased expression of NQO1 mRNA CTD PMID:38903859 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 affects expression EXP fluorotelomer alcohols affects the expression of PCK1 mRNA CTD PMID:38903859 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191 		JBrowse link
G Pdzk1 PDZ domain containing 1 increases expression ISO fluorotelomer alcohols results in increased expression of PDZK1 mRNA CTD PMID:16393665 NCBI chr 2:184,376,161...184,407,514
Ensembl chr 2:184,376,161...184,407,514 		JBrowse link
G Pgr progesterone receptor increases expression ISO fluorotelomer alcohols results in increased expression of PGR mRNA CTD PMID:16393665 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
G Scd stearoyl-CoA desaturase increases expression EXP fluorotelomer alcohols results in increased expression of SCD mRNA CTD PMID:38903859 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Slc22a7 solute carrier family 22 member 7 increases expression EXP fluorotelomer alcohols results in increased expression of SLC22A7 mRNA CTD PMID:21530637 NCBI chr 9:14,547,073...14,554,354
Ensembl chr 9:14,547,849...14,553,921 		JBrowse link
G Spi1 Spi-1 proto-oncogene decreases expression ISO fluorotelomer alcohols results in decreased expression of SPI1 mRNA CTD PMID:30794351 NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393 		JBrowse link
G Star steroidogenic acute regulatory protein decreases expression ISO fluorotelomer alcohols results in decreased expression of STAR mRNA; fluorotelomer alcohols results in decreased expression of STAR protein CTD PMID:20615422 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Tat tyrosine aminotransferase affects expression EXP fluorotelomer alcohols affects the expression of TAT mRNA CTD PMID:38903859 NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031 		JBrowse link
G Tff1 trefoil factor 1 increases expression ISO fluorotelomer alcohols results in increased expression of TFF1 mRNA CTD PMID:16393665 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597 		JBrowse link
G Tnf tumor necrosis factor decreases expression ISO fluorotelomer alcohols results in decreased expression of TNF mRNA CTD PMID:30536526 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tspo translocator protein decreases expression ISO fluorotelomer alcohols results in decreased expression of TSPO mRNA CTD PMID:23142464 NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450 		JBrowse link
decan-1-ol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cftr CF transmembrane conductance regulator increases activity ISO n-decyl alcohol results in increased activity of CFTR protein CTD PMID:14967738 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756 		JBrowse link
dodecan-1-ol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf3 activating transcription factor 3 increases expression ISO Dodecanol analog results in increased expression of ATF3 mRNA CTD PMID:27965148 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO Dodecanol analog results in increased expression of DNAJB4 mRNA CTD PMID:27965148 NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Dodecanol analog results in increased expression of GCLM mRNA CTD PMID:27965148 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
heptan-1-ol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cftr CF transmembrane conductance regulator increases activity ISO Heptanol results in increased activity of CFTR protein CTD PMID:14967738 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756 		JBrowse link
G Gja1 gap junction protein, alpha 1 decreases phosphorylation EXP Heptanol results in decreased phosphorylation of GJA1 protein CTD PMID:16563290 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
monohexyl phthalate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsf1 heat shock transcription factor 1 increases activity ISO mono-n-hexyl phthalate results in increased activity of HSF1 protein CTD PMID:34170685 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha affects binding ISO mono-n-hexyl phthalate binds to PPARA protein CTD PMID:23843199 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta affects binding ISO mono-n-hexyl phthalate binds to PPARB protein CTD PMID:23843199 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects binding ISO mono-n-hexyl phthalate binds to PPARG protein CTD PMID:23843199 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
monooctyl phthalate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppara peroxisome proliferator activated receptor alpha affects binding ISO mono-n-octyl phthalate binds to PPARA protein CTD PMID:23843199 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta affects binding ISO mono-n-octyl phthalate binds to PPARB protein CTD PMID:23843199 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects binding ISO mono-n-octyl phthalate binds to PPARG protein CTD PMID:23843199 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
nonan-1-ol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO 1-nonanol binds to and results in increased activity of NR1I3 protein alternative form CTD PMID:20869355 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
octan-1-ol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide multiple interactions
increases metabolic processing		 ISO Pentachlorophenol inhibits the reaction [ADH5 protein results in increased metabolism of 1-Octanol] CTD PMID:19822198 NCBI chr 2:226,975,184...226,987,591
Ensembl chr 2:226,947,466...226,987,591 		JBrowse link
G Cftr CF transmembrane conductance regulator increases activity
multiple interactions		 ISO 1-Octanol results in increased activity of CFTR protein; 1-Octanol results in increased activity of CFTR protein mutant form
Glyburide inhibits the reaction [1-Octanol results in increased activity of CFTR protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [1-Octanol results in increased activity of CFTR protein]		 CTD PMID:14967738 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756 		JBrowse link
G Tnf tumor necrosis factor increases expression ISO 1-Octanol results in increased expression of TNF protein CTD PMID:29953848 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
octan-2-ol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cftr CF transmembrane conductance regulator increases activity ISO 2-octanol results in increased activity of CFTR protein CTD PMID:14967738 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    chemical entity 19878
      molecular entity 19878
        polyatomic entity 19830
          heteroatomic molecular entity 19787
            hydroxides 19347
              organic hydroxy compound 18957
                alcohol 15719
                  fatty alcohol 6137
                    medium-chain fatty alcohol 58
                      (E)-dec-3-en-2-ol 0
                      10-undecen-1-ol 0
                      2-butyl-1-octanol + 0
                      3,7,11-trimethyldodecan-1-ol 0
                      3,7-dimethyl-3-octanol 0
                      4-hydroxynonenol + 0
                      9-methyldecan-1-ol 0
                      decanol + 48
                      dodecanol + 3
                      heptanol + 2
                      hexanol + 4
                      nonanol + 1
                      oct-1-en-3-ol + 0
                      octanol + 6
                      undec-1-en-1-ol 0
                      undecanol + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      carbon group element atom 19757
                        carbon atom 19754
                          organic molecular entity 19754
                            heteroorganic entity 19512
                              organochalcogen compound 19275
                                organooxygen compound 19191
                                  carbon oxoacid 18658
                                    carboxylic acid 18655
                                      monocarboxylic acid 18004
                                        fatty acid 16838
                                          fatty acid derivative 8982
                                            fatty alcohol 6137
                                              medium-chain fatty alcohol 58
                                                (E)-dec-3-en-2-ol 0
                                                10-undecen-1-ol 0
                                                2-butyl-1-octanol + 0
                                                3,7,11-trimethyldodecan-1-ol 0
                                                3,7-dimethyl-3-octanol 0
                                                4-hydroxynonenol + 0
                                                9-methyldecan-1-ol 0
                                                decanol + 48
                                                dodecanol + 3
                                                heptanol + 2
                                                hexanol + 4
                                                nonanol + 1
                                                oct-1-en-3-ol + 0
                                                octanol + 6
                                                undec-1-en-1-ol 0
                                                undecanol + 0
paths to the root