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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:(+)-Erythraline
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Accession:CHEBI:196318 term browser browse the term
Synonyms:exact_synonym: (1S,19R)-19-methoxy-5,7-dioxa-13-azapentacyclo[11.7.0.01,16.02,10.04,8]icosa-2,4(8),9,15,17-pentaene
 related_synonym: Formula=C18H19NO3;   InChI=1S/C18H19NO3/c1-20-14-3-2-13-5-7-19-6-4-12-8-16-17(22-11-21-16)9-15(12)18(13,19)10-14/h2-3,5,8-9,14H,4,6-7,10-11H2,1H3/t14-,18-/m0/s1;   InChIKey=TVOFUERNMZTYRM-KSSFIOAISA-N;   SMILES=O([C@@H]1C[C@@]23N(CCC=4C2=CC=5OCOC5C4)CC=C3C=C1)C
 xref: Chemspider:4476106
 xref_mesh: MESH:C586471


show annotations for term's descendants           Sort by:
(+)-Erythraline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO erythraline inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of CHUK protein] CTD PMID:23902980 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 decreases activity ISO erythraline results in decreased activity of MAP3K7 protein CTD PMID:23902980 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO erythraline inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein] CTD PMID:23902980 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO erythraline inhibits the reaction [[Lipopolysaccharides results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide]; erythraline inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:23902980 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO erythraline inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein] CTD PMID:23902980 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19901
    role 19871
      biological role 19869
        biochemical role 19576
          metabolite 19563
            alkaloid 8024
              (+)-Erythraline 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19901
    subatomic particle 19899
      composite particle 19899
        hadron 19899
          baryon 19899
            nucleon 19899
              atomic nucleus 19899
                atom 19899
                  main group element atom 19838
                    main group molecular entity 19838
                      p-block molecular entity 19838
                        carbon group molecular entity 19778
                          organic molecular entity 19775
                            heteroorganic entity 19534
                              organonitrogen compound 18859
                                alkaloid 8024
                                  (+)-Erythraline 5
paths to the root