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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:T-type calcium channel blocker
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Accession:CHEBI:194338 term browser browse the term
Definition:Any agent that interferes with the activity of T-type calcium channels.
Synonyms:related_synonym: T-type calcium channel antagonist;   T-type calcium channel antagonists;   T-type calcium channel blockers
 xref: PMID:30372652;   PMID:36738196;   Wikipedia:T-type_calcium_channel


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6-prenylnaringenin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
multiple interactions		 ISO 6-prenylnaringenin results in increased expression of CYP1A1 mRNA; 6-prenylnaringenin results in increased expression of CYP1A1 protein
6-prenylnaringenin inhibits the reaction [DNMT1 protein binds to CYP1A1 promoter]; 6-prenylnaringenin inhibits the reaction [Estradiol promotes the reaction [DNMT1 protein binds to CYP1A1 promoter]]; 6-prenylnaringenin inhibits the reaction [Estradiol results in decreased expression of CYP1A1 mRNA]		 CTD PMID:27269377 PMID:32986415 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO 6-prenylnaringenin results in increased expression of CYP1B1 mRNA CTD PMID:27269377 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions ISO 6-prenylnaringenin inhibits the reaction [DNMT1 protein binds to CYP1A1 promoter]; 6-prenylnaringenin inhibits the reaction [Estradiol promotes the reaction [DNMT1 protein binds to CYP1A1 promoter]] CTD PMID:32986415 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
decreases expression		 ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [6-prenylnaringenin results in decreased expression of ESR1 protein]; 6-prenylnaringenin promotes the reaction [Estradiol results in decreased expression of ESR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [6-prenylnaringenin results in decreased expression of ESR1 protein] CTD PMID:32986415 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
ethosuximide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway increases expression
multiple interactions		 EXP Ethosuximide results in increased expression of APC mRNA
Ethosuximide inhibits the reaction [APP protein modified form results in decreased expression of APC mRNA]		 CTD PMID:26420483 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G App amyloid beta precursor protein multiple interactions EXP Ethosuximide inhibits the reaction [APP protein modified form results in decreased expression of APC mRNA]; Ethosuximide inhibits the reaction [APP protein modified form results in decreased expression of AXIN1 mRNA]; Ethosuximide inhibits the reaction [APP protein modified form results in decreased expression of CCND1 mRNA]; Ethosuximide inhibits the reaction [APP protein modified form results in decreased expression of CTNNB1 mRNA]; Ethosuximide inhibits the reaction [APP protein modified form results in decreased expression of DCX mRNA]; Ethosuximide inhibits the reaction [APP protein modified form results in decreased expression of FZD1 mRNA]; Ethosuximide inhibits the reaction [APP protein modified form results in decreased expression of LEF1 mRNA]; Ethosuximide inhibits the reaction [APP protein modified form results in decreased expression of LRP6 mRNA]; Ethosuximide inhibits the reaction [APP protein modified form results in decreased expression of NES mRNA]; Ethosuximide inhibits the reaction [APP protein modified form results in decreased expression of NEUROD1 mRNA]; Ethosuximide inhibits the reaction [APP protein modified form results in decreased expression of PAX6 mRNA]; Ethosuximide inhibits the reaction [APP protein modified form results in decreased expression of STAT3 mRNA]; Ethosuximide inhibits the reaction [APP protein modified form results in decreased expression of WNT1 mRNA]; Ethosuximide inhibits the reaction [APP protein modified form results in decreased expression of WNT3 mRNA]; Ethosuximide inhibits the reaction [APP protein modified form results in increased expression of DKK1 mRNA]; Ethosuximide inhibits the reaction [APP protein modified form results in increased expression of GSK3B mRNA]; Ethosuximide inhibits the reaction [APP protein modified form results in increased expression of WIF1 mRNA] CTD PMID:26420483 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Axin1 axin 1 multiple interactions
increases expression		 EXP Ethosuximide inhibits the reaction [APP protein modified form results in decreased expression of AXIN1 mRNA]
Ethosuximide results in increased expression of AXIN1 mRNA		 CTD PMID:26420483 NCBI chr10:15,163,477...15,215,615
Ensembl chr10:15,163,684...15,215,615 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions
increases expression		 EXP Ethosuximide inhibits the reaction [APP protein modified form results in decreased expression of CCND1 mRNA]
Ethosuximide results in increased expression of CCND1 mRNA		 CTD PMID:26420483 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
increases expression
decreases phosphorylation		 EXP
ISO		 Ethosuximide inhibits the reaction [APP protein modified form results in decreased expression of CTNNB1 mRNA]
Ethosuximide results in increased expression of CTNNB1 mRNA
Ethosuximide results in decreased phosphorylation of CTNNB1 protein
DKK1 protein inhibits the reaction [Ethosuximide results in decreased phosphorylation of CTNNB1 protein]		 CTD PMID:26420483 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity ISO Ethosuximide results in decreased activity of CYP19A1 protein CTD PMID:17959350 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 affects metabolic processing EXP CYP2E1 protein affects the metabolism of Ethosuximide CTD PMID:1438522 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Dcx doublecortin multiple interactions
increases expression		 EXP Ethosuximide inhibits the reaction [APP protein modified form results in decreased expression of DCX mRNA]
Ethosuximide results in increased expression of DCX mRNA		 CTD PMID:26420483 NCBI chr  X:107,430,767...107,573,612
Ensembl chr  X:107,430,767...107,507,476 		JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 multiple interactions
decreases expression		 ISO
EXP		 DKK1 protein inhibits the reaction [Ethosuximide results in decreased phosphorylation of CTNNB1 protein]; DKK1 protein inhibits the reaction [Ethosuximide results in increased phosphorylation of GSK3B protein]
Ethosuximide inhibits the reaction [APP protein modified form results in increased expression of DKK1 mRNA]
Ethosuximide results in decreased expression of DKK1 mRNA		 CTD PMID:26420483 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202 		JBrowse link
G Fzd1 frizzled class receptor 1 increases expression
multiple interactions		 EXP Ethosuximide results in increased expression of FZD1 mRNA
Ethosuximide inhibits the reaction [APP protein modified form results in decreased expression of FZD1 mRNA]		 CTD PMID:26420483 NCBI chr 4:29,310,303...29,314,701
Ensembl chr 4:29,310,091...29,312,643
Ensembl chr 4:29,310,091...29,312,643 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
decreases expression
increases phosphorylation		 EXP
ISO		 Ethosuximide inhibits the reaction [APP protein modified form results in increased expression of GSK3B mRNA]
Ethosuximide results in decreased expression of GSK3B mRNA
Ethosuximide results in increased phosphorylation of GSK3B protein
DKK1 protein inhibits the reaction [Ethosuximide results in increased phosphorylation of GSK3B protein]		 CTD PMID:26420483 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 multiple interactions EXP
ISO		 Ethosuximide inhibits the reaction [[KCNJ5 protein binds to KCNJ3 protein] which results in increased transport of Potassium]; Ethosuximide inhibits the reaction [Ethanol promotes the reaction [[KCNJ3 protein binds to KCNJ6 protein] which results in increased transport of Potassium]]
Ethosuximide inhibits the reaction [[KCNJ3 protein binds to KCNJ6 protein] which results in increased transport of Potassium]		 CTD PMID:18977371 NCBI chr 3:39,944,896...40,106,646
Ensembl chr 3:39,945,351...40,109,124 		JBrowse link
G Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 multiple interactions EXP Ethosuximide inhibits the reaction [[KCNJ5 protein binds to KCNJ3 protein] which results in increased transport of Potassium] CTD PMID:18977371 NCBI chr 8:30,724,923...30,753,083
Ensembl chr 8:30,724,925...30,753,518 		JBrowse link
G Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 multiple interactions ISO
EXP		 Ethosuximide inhibits the reaction [[KCNJ3 protein binds to KCNJ6 protein] which results in increased transport of Potassium]
Ethosuximide inhibits the reaction [Ethanol promotes the reaction [[KCNJ3 protein binds to KCNJ6 protein] which results in increased transport of Potassium]]		 CTD PMID:18977371 NCBI chr11:34,061,702...34,308,758
Ensembl chr11:34,061,708...34,308,758 		JBrowse link
G Lef1 lymphoid enhancer binding factor 1 increases expression
multiple interactions		 EXP Ethosuximide results in increased expression of LEF1 mRNA
Ethosuximide inhibits the reaction [APP protein modified form results in decreased expression of LEF1 mRNA]		 CTD PMID:26420483 NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794 		JBrowse link
G Lrp6 LDL receptor related protein 6 increases expression
multiple interactions		 EXP Ethosuximide results in increased expression of LRP6 mRNA
Ethosuximide inhibits the reaction [APP protein modified form results in decreased expression of LRP6 mRNA]		 CTD PMID:26420483 NCBI chr 4:167,269,856...167,400,364
Ensembl chr 4:167,270,353...167,400,497 		JBrowse link
G Nes nestin increases expression
multiple interactions		 EXP Ethosuximide results in increased expression of NES mRNA
Ethosuximide inhibits the reaction [APP protein modified form results in decreased expression of NES mRNA]		 CTD PMID:26420483 NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777 		JBrowse link
G Neurod1 neuronal differentiation 1 increases expression
multiple interactions		 EXP Ethosuximide results in increased expression of NEUROD1 mRNA
Ethosuximide inhibits the reaction [APP protein modified form results in decreased expression of NEUROD1 mRNA]		 CTD PMID:26420483 NCBI chr 3:64,359,554...64,363,526
Ensembl chr 3:64,359,395...64,363,649 		JBrowse link
G Pax6 paired box 6 increases expression
multiple interactions		 EXP Ethosuximide results in increased expression of PAX6 mRNA
Ethosuximide inhibits the reaction [APP protein modified form results in decreased expression of PAX6 mRNA]		 CTD PMID:26420483 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014 		JBrowse link
G RT1-DMb RT1 class II, locus DMb affects expression ISO Ethosuximide affects the expression of HLA-DMB mRNA CTD PMID:25811541 NCBI chr20:4,693,102...4,700,340
Ensembl chr20:4,693,103...4,700,340 		JBrowse link
G RT1-Ha RT1 class II, locus Ha affects expression ISO Ethosuximide affects the expression of HLA-DPA1 mRNA CTD PMID:25811541 NCBI chr20:4,760,631...4,770,662
Ensembl chr20:4,760,118...4,770,244 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases expression
multiple interactions		 EXP Ethosuximide results in increased expression of STAT3 mRNA
Ethosuximide inhibits the reaction [APP protein modified form results in decreased expression of STAT3 mRNA]		 CTD PMID:26420483 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Wif1 Wnt inhibitory factor 1 multiple interactions EXP Ethosuximide inhibits the reaction [APP protein modified form results in increased expression of WIF1 mRNA] CTD PMID:26420483 NCBI chr 7:56,548,060...56,618,364
Ensembl chr 7:56,548,053...56,618,360 		JBrowse link
G Wnt1 Wnt family member 1 multiple interactions
increases expression		 EXP Ethosuximide inhibits the reaction [APP protein modified form results in decreased expression of WNT1 mRNA]
Ethosuximide results in increased expression of WNT1 mRNA		 CTD PMID:26420483 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651 		JBrowse link
G Wnt3 Wnt family member 3 multiple interactions
increases expression		 EXP Ethosuximide inhibits the reaction [APP protein modified form results in decreased expression of WNT3 mRNA]
Ethosuximide results in increased expression of WNT3 mRNA		 CTD PMID:26420483 NCBI chr10:88,680,198...88,724,170
Ensembl chr10:88,680,248...88,724,099 		JBrowse link
Mibefradil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO Mibefradil results in decreased activity of ABCB11 protein CTD PMID:20829430 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Agt angiotensinogen multiple interactions ISO Mibefradil inhibits the reaction [AGT protein results in increased abundance of Aldosterone]; Mibefradil inhibits the reaction [AGT protein results in increased expression of CYP11B2 mRNA]; Mibefradil inhibits the reaction [AGT protein results in increased uptake of Calcium] CTD PMID:18331727 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G affects response to substance
multiple interactions		 ISO
EXP		 CACNA1G protein affects the susceptibility to Mibefradil
Mibefradil inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CACNA1G protein]		 CTD PMID:12130671 PMID:17110049 NCBI chr10:79,354,998...79,422,960
Ensembl chr10:79,355,008...79,422,752 		JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H multiple interactions EXP
ISO		 Mibefradil inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CACNA1H protein]
Mibefradil inhibits the reaction [CACNA1H protein results in increased transport of Calcium]		 CTD PMID:9930755 PMID:17110049 NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376 		JBrowse link
G Cacna1i calcium voltage-gated channel subunit alpha1 I multiple interactions EXP Mibefradil inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CACNA1I protein] CTD PMID:17110049 NCBI chr 7:111,835,996...111,947,418
Ensembl chr 7:111,836,012...111,944,688 		JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions EXP Mibefradil inhibits the reaction [Potassium results in increased secretion of CALCA protein] CTD PMID:18178321 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 multiple interactions ISO Mibefradil inhibits the reaction [AGT protein results in increased expression of CYP11B2 mRNA] CTD PMID:18331727 NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity ISO Mibefradil results in decreased activity of CYP3A4 protein CTD PMID:15860655 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Edn1 endothelin 1 multiple interactions EXP Mibefradil inhibits the reaction [[Sodium Chloride, Dietary co-treated with Desoxycorticosterone] results in increased expression of EDN1 mRNA] CTD PMID:8934362 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Hexa hexosaminidase subunit alpha multiple interactions EXP Mibefradil inhibits the reaction [Tetrachlorodibenzodioxin results in increased secretion of [HEXB protein binds to HEXA protein]] CTD PMID:19546254 NCBI chr 8:59,936,526...59,961,654
Ensembl chr 8:59,936,660...59,962,013 		JBrowse link
G Hexb hexosaminidase subunit beta multiple interactions EXP Mibefradil inhibits the reaction [Tetrachlorodibenzodioxin results in increased secretion of [HEXB protein binds to HEXA protein]] CTD PMID:19546254 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions
decreases activity		 ISO Mibefradil inhibits the reaction [KCNH2 protein results in increased transport of Thallium]
Mibefradil results in decreased activity of KCNH2 protein		 CTD PMID:21158687 PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 multiple interactions EXP Mibefradil inhibits the reaction [Tetrachlorodibenzodioxin results in increased secretion of LAMP1 protein] CTD PMID:19546254 NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883 		JBrowse link
zonisamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Car1 carbonic anhydrase 1 multiple interactions ISO zonisamide binds to and results in decreased activity of CA1 protein CTD PMID:17826101 NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208 		JBrowse link
G Car2 carbonic anhydrase 2 multiple interactions ISO zonisamide binds to and results in decreased activity of CA2 protein CTD PMID:17826101 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818 		JBrowse link
G Car3 carbonic anhydrase 3 multiple interactions ISO zonisamide binds to and results in decreased activity of CA3 protein CTD PMID:17826101 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280 		JBrowse link
G Drd1 dopamine receptor D1 multiple interactions EXP DRD1 protein promotes the reaction [zonisamide affects the secretion of Dopamine]; DRD1 protein promotes the reaction [zonisamide affects the secretion of gamma-Aminobutyric Acid] CTD PMID:19482038 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP zonisamide inhibits the reaction [Tacrine results in increased expression of FOS protein] CTD PMID:18693129 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions ISO zonisamide inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GFAP protein] CTD PMID:19199078 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589 		JBrowse link
G Ifng interferon gamma decreases expression ISO zonisamide results in decreased expression of IFNG protein CTD PMID:10982153 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Maob monoamine oxidase B multiple interactions
decreases activity		 ISO zonisamide inhibits the reaction [[MAOB protein results in increased metabolism of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] which results in increased chemical synthesis of 1-Methyl-4-phenylpyridinium]; zonisamide inhibits the reaction [Selegiline binds to MAOB protein]
zonisamide results in decreased activity of MAOB protein		 CTD PMID:19948168 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003 		JBrowse link
G Nos2 nitric oxide synthase 2 increases expression EXP zonisamide results in increased expression of NOS2 mRNA CTD PMID:12429386 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Slc1a1 solute carrier family 1 member 1 increases expression EXP zonisamide results in increased expression of SLC1A1 protein CTD PMID:12941455 NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402 		JBrowse link
G Th tyrosine hydroxylase increases expression
multiple interactions		 ISO Zonisamide results in increased expression of TH mRNA; Zonisamide results in increased expression of TH protein
zonisamide results in increased expression of TH protein
[zonisamide co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] affects the activity of TH protein; zonisamide inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH protein]		 CTD PMID:19199078 PMID:19948168 PMID:20196486 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    role 19850
      biological role 19848
        pharmacological role 19080
          antagonist 17237
            calcium channel blocker 7165
              T-type calcium channel blocker 53
                6-prenylnaringenin 4
                Mibefradil 13
                NNC 55-0396 (free base) + 0
                NNC 55-0396 dihydrochloride 0
                apinocaltamide 0
                ethosuximide + 25
                ulixacaltamide 0
                zonisamide 11
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    role 19850
      biological role 19848
        biophysical role 14048
          membrane transport modulator 13884
            calcium channel modulator 9705
              calcium channel blocker 7165
                T-type calcium channel blocker 53
                  6-prenylnaringenin 4
                  Mibefradil 13
                  NNC 55-0396 (free base) + 0
                  NNC 55-0396 dihydrochloride 0
                  apinocaltamide 0
                  ethosuximide + 25
                  ulixacaltamide 0
                  zonisamide 11
paths to the root