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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2''-galloylhyperin
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Accession:CHEBI:190973 term browser browse the term
Synonyms:exact_synonym: [(2S,3R,4S,5R,6R)-2-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxochromen-3-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl] 3,4,5-trihydroxybenzoate
 related_synonym: Formula=C28H24O16;   InChI=1S/C28H24O16/c29-8-18-21(37)23(39)26(43-27(40)10-4-15(34)20(36)16(35)5-10)28(42-18)44-25-22(38)19-14(33)6-11(30)7-17(19)41-24(25)9-1-2-12(31)13(32)3-9/h1-7,18,21,23,26,28-37,39H,8H2/t18-,21+,23+,26-,28+/m1/s1;   InChIKey=PXGWEUQZDRUMRE-UNZYZCBSSA-N;   SMILES=O1[C@@H]([C@H](O)[C@H](O)[C@@H](OC(=O)C2=CC(O)=C(O)C(O)=C2)[C@@H]1OC3=C(OC=4C(C3=O)=C(O)C=C(O)C4)C5=CC(O)=C(O)C=C5)CO
 xref: CAS:53209-27-1;   Chemspider:4955742
 xref_mesh: MESH:C087939



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2''-galloylhyperin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO 2''-galloylhyperin inhibits the reaction [Hydrogen Peroxide results in increased expression of BAX protein] CTD PMID:28213291 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO 2''-galloylhyperin inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein] CTD PMID:28213291 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Casp3 caspase 3 multiple interactions ISO 2''-galloylhyperin inhibits the reaction [Hydrogen Peroxide results in increased expression of CASP3 protein modified form] CTD PMID:28213291 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO 2''-galloylhyperin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CXCL2 protein] CTD PMID:30849337 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO 2''-galloylhyperin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CXCL1 protein] CTD PMID:30849337 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO 2''-galloylhyperin results in increased expression of HMOX1 protein
2''-galloylhyperin promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of HMOX1 protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [2''-galloylhyperin results in increased expression of HMOX1 protein]
CTD PMID:28213291 PMID:30849337 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Il6 interleukin 6 multiple interactions ISO 2''-galloylhyperin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 protein] CTD PMID:30849337 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO 2''-galloylhyperin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK1 protein]
2''-galloylhyperin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein]
CTD PMID:28213291 PMID:30849337 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO 2''-galloylhyperin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein]
2''-galloylhyperin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK3 protein]
CTD PMID:28213291 PMID:30849337 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO 2''-galloylhyperin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] CTD PMID:28213291 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO 2''-galloylhyperin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK9 protein] CTD PMID:28213291 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO 2''-galloylhyperin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased activity of MPO protein] CTD PMID:30849337 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO 2''-galloylhyperin affects the localization of and results in increased activity of NFE2L2 protein; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [2''-galloylhyperin affects the localization of and results in increased activity of NFE2L2 protein]
2''-galloylhyperin promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NFE2L2 protein]
CTD PMID:28213291 PMID:30849337 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO 2''-galloylhyperin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of NFKBIA protein] CTD PMID:30849337 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO 2''-galloylhyperin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of and affects the localization of RELA protein] CTD PMID:30849337 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO 2''-galloylhyperin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein] CTD PMID:30849337 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link

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Path 1
Term Annotations click to browse term
  CHEBI ontology 19878
    chemical entity 19876
      atom 19876
        nonmetal atom 19798
          oxygen atom 19538
            oxygen molecular entity 19538
              flavonoids 11617
                2''-galloylhyperin 16
Path 2
Term Annotations click to browse term
  CHEBI ontology 19878
    subatomic particle 19876
      composite particle 19876
        hadron 19876
          baryon 19876
            nucleon 19876
              atomic nucleus 19876
                atom 19876
                  main group element atom 19815
                    p-block element atom 19815
                      carbon group element atom 19755
                        carbon atom 19752
                          organic molecular entity 19752
                            heteroorganic entity 19509
                              organochalcogen compound 19270
                                organooxygen compound 19186
                                  carbohydrates and carbohydrate derivatives 15282
                                    carbohydrate 15282
                                      carbohydrate derivative 14298
                                        glycosyl compound 13063
                                          glycoside 11830
                                            2''-galloylhyperin 16
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