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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:inorganic aluminium salt
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Accession:CHEBI:190432 term browser browse the term
Definition:A aluminium salt that lacks C-H bonds


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aluminium sulfate (anhydrous) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam9 ADAM metallopeptidase domain 9 decreases expression ISO aluminum sulfate results in decreased expression of ADAM9 mRNA CTD PMID:15961160 NCBI chr16:67,022,538...67,101,647
Ensembl chr16:67,022,655...67,100,917 		JBrowse link
G App amyloid beta precursor protein affects expression
increases expression		 ISO aluminum sulfate affects the expression of APP protein
aluminum sulfate results in increased expression of APP mRNA		 CTD PMID:10721010 PMID:15961160 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Atf4 activating transcription factor 4 multiple interactions ISO [Ovalbumin co-treated with aluminum sulfate] results in increased expression of ATF4 mRNA; [Ovalbumin co-treated with aluminum sulfate] results in increased expression of ATF4 protein; Dexamethasone inhibits the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased expression of ATF4 mRNA]; Gu-Ben-Fang-Xiao decoction inhibits the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased expression of ATF4 mRNA]; Gu-Ben-Fang-Xiao decoction inhibits the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased expression of ATF4 protein]; montelukast inhibits the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased expression of ATF4 mRNA] CTD PMID:27660012 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Casp1 caspase 1 multiple interactions ISO [Lipopolysaccharides co-treated with aluminum sulfate] results in increased activity of CASP1 protein; CASP1 protein promotes the reaction [[Lipopolysaccharides co-treated with aluminum sulfate] results in increased secretion of IL1B protein]; leptomycin B inhibits the reaction [[Lipopolysaccharides co-treated with aluminum sulfate] results in increased activity of CASP1 protein] CTD PMID:23430110 PMID:24158569 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 multiple interactions ISO [Ovalbumin co-treated with aluminum sulfate] results in increased secretion of CCL11 protein CTD PMID:27660012 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926 		JBrowse link
G Ctsb cathepsin B increases expression ISO aluminum sulfate results in increased expression of CTSB protein CTD PMID:24158569 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO [Ovalbumin co-treated with aluminum sulfate] results in increased secretion of CXCL2 protein CTD PMID:27660012 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO [Ovalbumin co-treated with aluminum sulfate] results in increased secretion of CXCL1 protein; Dexamethasone inhibits the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased secretion of CXCL1 protein]; Gu-Ben-Fang-Xiao decoction inhibits the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased secretion of CXCL1 protein] CTD PMID:27660012 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511 		JBrowse link
G Daxx death-domain associated protein increases expression ISO aluminum sulfate results in increased expression of DAXX mRNA CTD PMID:15961160 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO [Ovalbumin co-treated with aluminum sulfate] results in increased expression of DDIT3 mRNA; [Ovalbumin co-treated with aluminum sulfate] results in increased expression of DDIT3 protein; Gu-Ben-Fang-Xiao decoction inhibits the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased expression of DDIT3 mRNA]; Gu-Ben-Fang-Xiao decoction inhibits the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased expression of DDIT3 protein]; montelukast inhibits the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased expression of DDIT3 mRNA]; montelukast inhibits the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased expression of DDIT3 protein] CTD PMID:27660012 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions ISO [Ovalbumin co-treated with aluminum sulfate] results in increased expression of EIF2AK3 mRNA; [Ovalbumin co-treated with aluminum sulfate] results in increased expression of EIF2AK3 protein; Gu-Ben-Fang-Xiao decoction inhibits the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased expression of EIF2AK3 mRNA]; Gu-Ben-Fang-Xiao decoction inhibits the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased expression of EIF2AK3 protein]; montelukast inhibits the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased expression of EIF2AK3 mRNA] CTD PMID:27660012 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha multiple interactions ISO [Ovalbumin co-treated with aluminum sulfate] results in increased expression of and results in increased phosphorylation of EIF2S1 protein; [Ovalbumin co-treated with aluminum sulfate] results in increased expression of EIF2S1 mRNA; Dexamethasone inhibits the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased expression of EIF2S1 mRNA]; Gu-Ben-Fang-Xiao decoction inhibits the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased expression of EIF2S1 mRNA]; Gu-Ben-Fang-Xiao decoction inhibits the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased phosphorylation of EIF2S1 protein] CTD PMID:27660012 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions ISO [Ovalbumin co-treated with aluminum sulfate] results in increased expression of ERN1 mRNA; [Ovalbumin co-treated with aluminum sulfate] results in increased expression of ERN1 protein; Dexamethasone inhibits the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased expression of ERN1 mRNA]; Dexamethasone inhibits the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased expression of ERN1 protein]; Gu-Ben-Fang-Xiao decoction inhibits the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased expression of ERN1 mRNA]; Gu-Ben-Fang-Xiao decoction inhibits the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased expression of ERN1 protein]; montelukast inhibits the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased expression of ERN1 mRNA]; montelukast inhibits the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased expression of ERN1 protein] CTD PMID:27660012 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G Gata2 GATA binding protein 2 decreases expression ISO aluminum sulfate results in decreased expression of GATA2 mRNA CTD PMID:15961160 NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761 		JBrowse link
G Gtf2h1 general transcription factor IIH subunit 1 decreases expression ISO aluminum sulfate results in decreased expression of GTF2H1 mRNA CTD PMID:15961160 NCBI chr 1:97,321,417...97,349,455
Ensembl chr 1:97,321,394...97,349,455 		JBrowse link
G Ifng interferon gamma multiple interactions ISO [Ovalbumin co-treated with aluminum sulfate] results in increased expression of IFNG protein; Gu-Ben-Fang-Xiao decoction promotes the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased expression of IFNG protein]; montelukast promotes the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased expression of IFNG protein] CTD PMID:27660012 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Igf1 insulin-like growth factor 1 increases secretion ISO aluminum sulfate results in increased secretion of IGF1 protein CTD PMID:7685579 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igf2 insulin-like growth factor 2 increases secretion ISO aluminum sulfate results in increased secretion of IGF2 mRNA; aluminum sulfate results in increased secretion of IGF2 protein CTD PMID:7685579 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 decreases secretion ISO aluminum sulfate results in decreased secretion of IGFBP3 protein CTD PMID:7685579 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083 		JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 decreases secretion ISO aluminum sulfate results in decreased secretion of IGFBP4 protein CTD PMID:7685579 NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225 		JBrowse link
G Il18 interleukin 18 increases expression ISO aluminum sulfate results in increased expression of IL18 protein CTD PMID:16100009 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions		 ISO aluminum sulfate results in increased expression of IL1B mRNA
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[Lipopolysaccharides co-treated with aluminum sulfate] results in increased secretion of IL1B protein]; [Lipopolysaccharides co-treated with aluminum sulfate] results in increased expression of and results in increased activity of and results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with aluminum sulfate] results in increased secretion of IL1B protein; CASP1 protein promotes the reaction [[Lipopolysaccharides co-treated with aluminum sulfate] results in increased secretion of IL1B protein]; leptomycin B inhibits the reaction [[Lipopolysaccharides co-treated with aluminum sulfate] results in increased expression of IL1B protein]; NLRP3 protein promotes the reaction [[Lipopolysaccharides co-treated with aluminum sulfate] results in increased secretion of IL1B protein]; PYCARD protein promotes the reaction [[Lipopolysaccharides co-treated with aluminum sulfate] results in increased secretion of IL1B protein]
[Tetradecanoylphorbol Acetate co-treated with aluminum sulfate] results in increased secretion of IL1B protein; bafilomycin A1 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with aluminum sulfate] results in increased secretion of IL1B protein]; Cytochalasin D inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with aluminum sulfate] results in increased secretion of IL1B protein]; Sodium inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with aluminum sulfate] results in increased secretion of IL1B protein]		 CTD PMID:15961160 PMID:23430110 PMID:24158569 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Map2 microtubule-associated protein 2 multiple interactions EXP aluminum sulfate inhibits the reaction [Excitatory Amino Acid Agents results in increased metabolism of MAP2 protein] CTD PMID:10428068 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO [Ovalbumin co-treated with aluminum sulfate] results in increased expression of MAPK8 mRNA; [Ovalbumin co-treated with aluminum sulfate] results in increased expression of MAPK8 protein; Dexamethasone inhibits the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased expression of MAPK8 mRNA]; Gu-Ben-Fang-Xiao decoction inhibits the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased expression of MAPK8 mRNA]; Gu-Ben-Fang-Xiao decoction inhibits the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased expression of MAPK8 protein]; montelukast inhibits the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased expression of MAPK8 protein] CTD PMID:27660012 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapt microtubule-associated protein tau increases phosphorylation EXP aluminum sulfate results in increased phosphorylation of MAPT protein CTD PMID:11388372 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129 		JBrowse link
G Mir146a microRNA 146a multiple interactions ISO [ferrous sulfate co-treated with aluminum sulfate] results in increased expression of MIR146A mRNA; Curcumin inhibits the reaction [[ferrous sulfate co-treated with aluminum sulfate] results in increased expression of MIR146A mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[ferrous sulfate co-treated with aluminum sulfate] results in increased expression of MIR146A mRNA]; resveratrol analog inhibits the reaction [[ferrous sulfate co-treated with aluminum sulfate] results in increased expression of MIR146A mRNA] CTD PMID:22099153 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610 		JBrowse link
G Mtf1 metal-regulatory transcription factor 1 decreases expression ISO aluminum sulfate results in decreased expression of MTF1 mRNA CTD PMID:15961160 NCBI chr 5:137,062,319...137,107,136
Ensembl chr 5:137,062,376...137,107,136 		JBrowse link
G Nefl neurofilament light chain decreases expression ISO aluminum sulfate results in decreased expression of NEFL mRNA CTD PMID:15961160 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 increases expression
multiple interactions		 ISO aluminum sulfate results in increased expression of NFKB1 mRNA
[ferrous sulfate co-treated with aluminum sulfate] results in increased expression of and results in increased activity of [RELA protein binds to NFKB1 protein]		 CTD PMID:15961160 PMID:22099153 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO NLRP3 protein promotes the reaction [[Lipopolysaccharides co-treated with aluminum sulfate] results in increased secretion of IL1B protein] CTD PMID:24158569 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nos1 nitric oxide synthase 1 decreases expression EXP aluminum sulfate results in decreased expression of NOS1 protein CTD PMID:10428068 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 multiple interactions ISO [Ovalbumin co-treated with aluminum sulfate] results in increased expression of ORMDL3 mRNA; [Ovalbumin co-treated with aluminum sulfate] results in increased expression of ORMDL3 protein; Gu-Ben-Fang-Xiao decoction inhibits the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased expression of ORMDL3 mRNA]; montelukast inhibits the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased expression of ORMDL3 mRNA] CTD PMID:27660012 NCBI chr10:83,590,052...83,596,035
Ensembl chr10:83,590,071...83,598,620 		JBrowse link
G P2rx1 purinergic receptor P2X 1 decreases expression ISO aluminum sulfate results in decreased expression of P2RX1 mRNA CTD PMID:15961160 NCBI chr10:57,618,586...57,633,648
Ensembl chr10:57,618,586...57,633,623 		JBrowse link
G Pla2g4a phospholipase A2 group 4A increases expression ISO aluminum sulfate results in increased expression of PLA2G4A mRNA CTD PMID:15961160 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266 		JBrowse link
G Pml PML nuclear body scaffold multiple interactions ISO [Lipopolysaccharides co-treated with aluminum sulfate] results in increased expression of PML protein CTD PMID:23430110 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO aluminum sulfate results in increased expression of PTGS2 mRNA CTD PMID:15961160 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Pycard PYD and CARD domain containing multiple interactions ISO PYCARD protein promotes the reaction [[Lipopolysaccharides co-treated with aluminum sulfate] results in increased secretion of IL1B protein] CTD PMID:24158569 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [ferrous sulfate co-treated with aluminum sulfate] results in increased expression of and results in increased activity of [RELA protein binds to NFKB1 protein] CTD PMID:22099153 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Robo2 roundabout guidance receptor 2 decreases expression ISO aluminum sulfate results in decreased expression of ROBO2 mRNA CTD PMID:15961160 NCBI chr11:12,528,949...14,096,726
Ensembl chr11:12,528,951...13,041,536 		JBrowse link
G Syn1 synapsin I decreases expression ISO aluminum sulfate results in decreased expression of SYN1 mRNA CTD PMID:15961160 NCBI chr  X:1,172,208...1,227,400
Ensembl chr  X:1,172,208...1,227,396 		JBrowse link
G Syp synaptophysin decreases expression ISO aluminum sulfate results in decreased expression of SYP mRNA CTD PMID:15961160 NCBI chr  X:14,849,444...14,864,553
Ensembl chr  X:14,849,444...14,864,745 		JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions ISO [Ovalbumin co-treated with aluminum sulfate] results in increased expression of XBP1 mRNA; [Ovalbumin co-treated with aluminum sulfate] results in increased expression of XBP1 protein; Dexamethasone inhibits the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased expression of XBP1 protein]; Gu-Ben-Fang-Xiao decoction inhibits the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased expression of XBP1 mRNA]; Gu-Ben-Fang-Xiao decoction inhibits the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased expression of XBP1 protein]; montelukast inhibits the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased expression of XBP1 mRNA]; montelukast inhibits the reaction [[Ovalbumin co-treated with aluminum sulfate] results in increased expression of XBP1 protein] CTD PMID:27660012 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19898
    chemical entity 19896
      chemical substance 14408
        mineral 4326
          mineral nutrient 510
            inorganic aluminium salt 42
              aluminium sulfate + 42
Path 2
Term Annotations click to browse term
  CHEBI ontology 19898
    subatomic particle 19896
      composite particle 19896
        hadron 19896
          baryon 19896
            nucleon 19896
              atomic nucleus 19896
                atom 19896
                  main group element atom 19835
                    p-block element atom 19835
                      boron group element atom 1138
                        aluminium atom 282
                          aluminium molecular entity 282
                            aluminium salt 51
                              inorganic aluminium salt 42
                                aluminium sulfate + 42
paths to the root