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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:3beta-(2-diethylaminoethoxy)androst-5-en-17-one hydrochloride
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Accession:CHEBI:190404 term browser browse the term
Definition:A hydrochloride obtained by reaction of 3beta-(2-diethylaminoethoxy)androst-5-en-17-one with one equivalent of hydrochloric acid. It is a cholesterol synthesis and transport inhibitor.
Synonyms:exact_synonym: 3beta-[2-(diethylamino)ethoxy]androst-5-en-17-one hydrochloride
 related_synonym: (3beta)-3-[2-(diethylamino)ethoxy]androst-5-en-17-one hydrochloride;   3beta-(2-diethylaminoethoxy)androst-5-en-17-one HCl;   Formula=C25H41NO2.ClH;   InChI=1S/C25H41NO2.ClH/c1-5-26(6-2)15-16-28-19-11-13-24(3)18(17-19)7-8-20-21-9-10-23(27)25(21,4)14-12-22(20)24;/h7,19-22H,5-6,8-17H2,1-4H3;1H/t19-,20-,21-,22-,24-,25-;/m0./s1;   InChIKey=GZFYZYBWLCYBMI-MYZJJQSMSA-N;   N,N-diethyl-2-[(17-oxoandrost-5-en-3beta-yl)oxy]ethanaminium chloride;   SMILES=Cl.[H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@H](CC[C@]12C)OCCN(CC)CC;   U 18666A;   U-18,666A;   U18666A
 xref: CAS:3039-71-2;   Chemspider:8129692
 xref_mesh: MESH:C006261
 xref: PMID:12622792;   PMID:16149744;   PMID:16771828;   PMID:18855586;   PMID:19158313;   PMID:19220841;   PMID:19440746;   PMID:22146564;   PMID:23250759;   PMID:25181483;   PMID:25688009;   PMID:26340949;   PMID:26344921;   PMID:26646182;   PMID:26815033;   PMID:27671775;   PMID:27707921;   PMID:28407359;   PMID:28722194;   PMID:28780424;   PMID:29530923;   PMID:29624387;   PMID:31174294;   PMID:31648726;   PMID:31963705;   PMID:33376205;   PMID:33403386;   PMID:33907281;   PMID:34047913;   PMID:34175669;   PMID:34502342;   PMID:34524402;   PMID:34671194;   PMID:34912322;   PMID:34919035;   PMID:35223543;   PMID:35309938;   Patent:WO2010083445


show annotations for term's descendants           Sort by:
3beta-(2-diethylaminoethoxy)androst-5-en-17-one hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpc1 glypican 1 decreases degradation ISO 3-beta-(2-(diethylamino)ethoxy)androst-5-en-17-one results in decreased degradation of GPC1 protein CTD PMID:21642435 NCBI chr 9:93,396,234...93,424,047
Ensembl chr 9:93,396,234...93,424,047 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO 3-beta-(2-(diethylamino)ethoxy)androst-5-en-17-one inhibits the reaction [[Lipopolysaccharides results in increased susceptibility to Silicon Dioxide] which results in increased secretion of IL1B protein] CTD PMID:36860548 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19899
    role 19869
      biological role 19867
        antimicrobial agent 18269
          antiviral agent 11356
            3beta-(2-diethylaminoethoxy)androst-5-en-17-one hydrochloride 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19899
    subatomic particle 19897
      composite particle 19897
        hadron 19897
          baryon 19897
            nucleon 19897
              atomic nucleus 19897
                atom 19897
                  main group element atom 19835
                    p-block element atom 19835
                      halogen 18703
                        chlorine atom 18489
                          chlorine molecular entity 18489
                            elemental chlorine 8796
                              monoatomic chlorine 8781
                                chloride 8781
                                  chloride salt 8781
                                    organic chloride salt 1107
                                      hydrochloride 738
                                        3beta-(2-diethylaminoethoxy)androst-5-en-17-one hydrochloride 2
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