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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:inorganic calcium salt
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Accession:CHEBI:190295 term browser browse the term
Definition:A calcium salt that lacks C-H bonds
Synonyms:xref: PMID:28457049


show annotations for term's descendants           Sort by:
calcium carbonate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bglap bone gamma-carboxyglutamate protein decreases expression ISO Calcium Carbonate results in decreased expression of BGLAP protein CTD PMID:2027271 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Capn1 calpain 1 increases activity ISO Calcium Carbonate analog results in increased activity of CAPN1 protein CTD PMID:24412303 NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177 		JBrowse link
G Casp3 caspase 3 increases activity ISO Calcium Carbonate analog results in increased activity of CASP3 protein CTD PMID:24412303 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Calcium Carbonate analog results in increased expression of DDIT3 CTD PMID:24412303 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Pth parathyroid hormone affects expression
decreases expression		 ISO Calcium Carbonate affects the expression of PTH protein
Calcium Carbonate results in decreased expression of PTH protein		 CTD PMID:1752077 PMID:2027271 PMID:3826069 PMID:7891547 PMID:8481062 More... NCBI chr 1:167,508,121...167,511,530
Ensembl chr 1:167,508,598...167,511,530 		JBrowse link
G Pthlh parathyroid hormone-like hormone decreases expression ISO Calcium Carbonate results in decreased expression of PTHLH protein CTD PMID:16006300 NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847 		JBrowse link
G Spp1 secreted phosphoprotein 1 decreases expression ISO Calcium Carbonate results in decreased expression of SPP1 protein CTD PMID:17977878 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
calcium dichloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam10 ADAM metallopeptidase domain 10 increases expression EXP Calcium Chloride results in increased expression of ADAM10 mRNA; Calcium Chloride results in increased expression of ADAM10 protein CTD PMID:20621845 NCBI chr 8:71,346,008...71,477,889
Ensembl chr 8:71,345,837...71,477,889 		JBrowse link
G Adam17 ADAM metallopeptidase domain 17 increases expression EXP Calcium Chloride results in increased expression of ADAM17 mRNA; Calcium Chloride results in increased expression of ADAM17 protein CTD PMID:20621845 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639 		JBrowse link
G Alpl alkaline phosphatase, biomineralization associated increases expression ISO Calcium Chloride results in increased expression of ALPL mRNA CTD PMID:25824407 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446 		JBrowse link
G Apoc3 apolipoprotein C3 increases expression ISO Calcium Chloride results in increased expression of APOC3 protein CTD PMID:25824407 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583 		JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 increases expression ISO Calcium Chloride results in increased expression of ATP5PF protein CTD PMID:25824407 NCBI chr11:23,881,594...23,889,581
Ensembl chr11:23,881,592...23,889,119 		JBrowse link
G Bag4 BAG cochaperone 4 increases expression ISO Calcium Chloride results in increased expression of BAG4 protein CTD PMID:25824407 NCBI chr16:66,288,678...66,305,893
Ensembl chr16:66,288,678...66,308,663 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein increases expression ISO Calcium Chloride results in increased expression of BGLAP mRNA CTD PMID:25824407 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Bicd2 BICD cargo adaptor 2 increases expression ISO Calcium Chloride results in increased expression of BICD2 protein CTD PMID:25824407 NCBI chr17:15,259,773...15,304,889
Ensembl chr17:15,259,773...15,304,889 		JBrowse link
G Calm3 calmodulin 3 multiple interactions ISO Calcium Chloride inhibits the reaction [CALM3 protein binds to and results in decreased activity of UBE3B protein] CTD PMID:28003368 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage		 EXP cordycepin inhibits the reaction [Calcium Chloride results in increased cleavage of CASP3 protein] CTD PMID:36731150 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 increases cleavage
multiple interactions		 EXP Calcium Chloride results in increased cleavage of CASP9 protein
cordycepin inhibits the reaction [Calcium Chloride results in increased cleavage of CASP9 protein]		 CTD PMID:36731150 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Casr calcium-sensing receptor multiple interactions
increases activity		 ISO Calcium Chloride promotes the reaction [Calcium results in increased phosphorylation of CASR protein]
Calcium Chloride results in increased activity of CASR protein		 CTD PMID:16316325 PMID:17376781 NCBI chr11:64,235,251...64,304,811
Ensembl chr11:64,235,251...64,304,811 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases phosphorylation
increases expression
multiple interactions		 ISO Calcium Chloride results in increased phosphorylation of CCL2 protein
Calcium Chloride results in increased expression of CCL2 mRNA; Calcium Chloride results in increased expression of CCL2 protein
Quercetin inhibits the reaction [Calcium Chloride results in increased expression of CCL2 protein]; Resveratrol inhibits the reaction [Calcium Chloride results in increased expression of CCL2 mRNA]; Resveratrol inhibits the reaction [Calcium Chloride results in increased phosphorylation of CCL2 protein]		 CTD PMID:21530968 PMID:22728078 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Cct6a chaperonin containing TCP1 subunit 6A decreases expression ISO Calcium Chloride results in decreased expression of CCT6A protein CTD PMID:25824407 NCBI chr12:26,872,736...26,883,125
Ensembl chr12:26,872,574...26,883,337 		JBrowse link
G Cd68 Cd68 molecule multiple interactions
increases expression		 ISO resveratrol inhibits the reaction [Calcium Chloride results in increased expression of CD68 mRNA] CTD PMID:21530968 NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions EXP Calcium Chloride inhibits the reaction [Azoxymethane results in decreased expression of CDKN1B protein] CTD PMID:12189186 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions EXP Calcium Chloride inhibits the reaction [Azoxymethane results in decreased expression of CDKN2A mRNA]; Calcium Chloride inhibits the reaction [Azoxymethane results in decreased expression of CDKN2A protein] CTD PMID:12189186 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha increases activity ISO Calcium Chloride results in increased activity of CEBPA protein CTD PMID:17214633 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412 		JBrowse link
G Clec3b C-type lectin domain family 3, member B increases expression ISO Calcium Chloride results in increased expression of CLEC3B protein CTD PMID:25824407 NCBI chr 8:122,810,120...122,815,837
Ensembl chr 8:122,810,149...122,815,835 		JBrowse link
G Clic3 chloride intracellular channel 3 decreases expression ISO Calcium Chloride results in decreased expression of CLIC3 protein CTD PMID:25824407 NCBI chr 3:8,271,416...8,274,023
Ensembl chr 3:8,272,097...8,274,018 		JBrowse link
G Cmtm6 CKLF-like MARVEL transmembrane domain containing 6 increases expression ISO Calcium Chloride results in increased expression of CMTM6 protein CTD PMID:25824407 NCBI chr 8:114,422,934...114,441,034
Ensembl chr 8:114,422,921...114,441,033 		JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression ISO Calcium Chloride results in increased expression of COL1A1 mRNA CTD PMID:25824407 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col8a1 collagen type VIII alpha 1 chain increases expression ISO Calcium Chloride results in increased expression of COL8A1 protein CTD PMID:25824407 NCBI chr11:42,776,851...42,906,432
Ensembl chr11:42,777,628...42,906,424 		JBrowse link
G Cops3 COP9 signalosome subunit 3 increases expression ISO Calcium Chloride results in increased expression of COPS3 protein CTD PMID:25824407 NCBI chr10:44,618,115...44,652,807
Ensembl chr10:44,618,115...44,641,597 		JBrowse link
G Cst3 cystatin C increases expression ISO Calcium Chloride results in increased expression of CST3 protein CTD PMID:25824407 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822 		JBrowse link
G Cthrc1 collagen triple helix repeat containing 1 decreases expression ISO Calcium Chloride results in decreased expression of CTHRC1 protein CTD PMID:25824407 NCBI chr 7:70,122,474...70,132,756
Ensembl chr 7:70,122,474...70,132,756 		JBrowse link
G Ctsb cathepsin B increases expression
multiple interactions		 ISO Calcium Chloride results in increased expression of CTSB protein
Quercetin inhibits the reaction [Calcium Chloride results in increased expression of CTSB protein]		 CTD PMID:22728078 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500 		JBrowse link
G Ctsk cathepsin K increases expression
multiple interactions		 ISO Calcium Chloride results in increased expression of CTSK protein
Quercetin inhibits the reaction [Calcium Chloride results in increased expression of CTSK protein]		 CTD PMID:22728078 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550 		JBrowse link
G Dcn decorin decreases expression ISO Calcium Chloride results in decreased expression of DCN protein CTD PMID:25824407 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270 		JBrowse link
G Ddx39b DExD-box helicase 39B increases expression ISO Calcium Chloride results in increased expression of DDX39B protein CTD PMID:25824407 NCBI chr20:3,547,702...3,585,064
Ensembl chr20:3,572,056...3,584,996 		JBrowse link
G Ehd2 EH-domain containing 2 increases expression ISO Calcium Chloride results in increased expression of EHD2 protein CTD PMID:25824407 NCBI chr 1:76,639,568...76,658,747
Ensembl chr 1:76,637,482...76,658,783 		JBrowse link
G F10 coagulation factor X multiple interactions ISO [F5 protein co-treated with F10 protein co-treated with Calcium Chloride] results in increased metabolism of F2 protein; aspalathin inhibits the reaction [[F5 protein co-treated with F10 protein co-treated with Calcium Chloride] results in increased metabolism of F2 protein]; nothofagin inhibits the reaction [[F5 protein co-treated with F10 protein co-treated with Calcium Chloride] results in increased metabolism of F2 protein] CTD PMID:25325928 NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141 		JBrowse link
G F11 coagulation factor XI multiple interactions ISO [F11 protein co-treated with Calcium Chloride] results in increased activity of F9 protein CTD PMID:6604052 NCBI chr16:46,987,988...47,009,015
Ensembl chr16:46,986,107...47,008,437 		JBrowse link
G F2 coagulation factor II, thrombin multiple interactions ISO [F5 protein co-treated with F10 protein co-treated with Calcium Chloride] results in increased metabolism of F2 protein; aspalathin inhibits the reaction [[F5 protein co-treated with F10 protein co-treated with Calcium Chloride] results in increased metabolism of F2 protein]; nothofagin inhibits the reaction [[F5 protein co-treated with F10 protein co-treated with Calcium Chloride] results in increased metabolism of F2 protein] CTD PMID:25325928 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G F5 coagulation factor V multiple interactions ISO [F5 protein co-treated with F10 protein co-treated with Calcium Chloride] results in increased metabolism of F2 protein; aspalathin inhibits the reaction [[F5 protein co-treated with F10 protein co-treated with Calcium Chloride] results in increased metabolism of F2 protein]; nothofagin inhibits the reaction [[F5 protein co-treated with F10 protein co-treated with Calcium Chloride] results in increased metabolism of F2 protein] CTD PMID:25325928 NCBI chr13:76,513,509...76,583,106
Ensembl chr13:76,513,255...76,582,317 		JBrowse link
G F9 coagulation factor IX multiple interactions ISO [F11 protein co-treated with Calcium Chloride] results in increased activity of F9 protein CTD PMID:6604052 NCBI chr  X:138,352,334...138,396,835
Ensembl chr  X:138,352,298...138,396,835 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase increases expression ISO Calcium Chloride results in increased expression of FYN protein CTD PMID:25824407 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Git1 GIT ArfGAP 1 increases expression ISO Calcium Chloride results in increased expression of GIT1 protein CTD PMID:25824407 NCBI chr10:62,342,082...62,356,379
Ensembl chr10:62,342,299...62,356,373 		JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 multiple interactions EXP [manganese chloride co-treated with Calcium Chloride] results in increased secretion of GNRH1 protein CTD PMID:18603625 NCBI chr15:41,972,482...41,976,690
Ensembl chr15:41,972,905...41,973,581
Ensembl chr15:41,972,905...41,973,581 		JBrowse link
G Gpr89b G protein-coupled receptor 89B increases expression ISO Calcium Chloride results in increased expression of GPR89B protein CTD PMID:25824407 NCBI chr 2:184,408,136...184,445,560
Ensembl chr 2:184,401,438...184,445,584 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
increases expression		 ISO Quercetin inhibits the reaction [Calcium Chloride results in increased expression of GPX1 mRNA]; resveratrol inhibits the reaction [Calcium Chloride results in increased expression of GPX1 mRNA] CTD PMID:21530968 PMID:24337353 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gpx3 glutathione peroxidase 3 multiple interactions
increases expression		 ISO Quercetin inhibits the reaction [Calcium Chloride results in increased expression of GPX3 mRNA]; resveratrol inhibits the reaction [Calcium Chloride results in increased expression of GPX3 mRNA] CTD PMID:21530968 PMID:24337353 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO Calcium Chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA] CTD PMID:21443188 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Htra1 HtrA serine peptidase 1 decreases expression ISO Calcium Chloride results in decreased expression of HTRA1 protein CTD PMID:25824407 NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379 		JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression
multiple interactions		 ISO Calcium Chloride results in increased expression of ICAM1 mRNA
resveratrol inhibits the reaction [Calcium Chloride results in increased expression of ICAM1 mRNA]		 CTD PMID:21530968 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Ift27 intraflagellar transport 27 increases expression ISO Calcium Chloride results in increased expression of IFT27 protein CTD PMID:25824407 NCBI chr 7:109,738,622...109,754,416
Ensembl chr 7:109,738,622...109,754,416 		JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions		 ISO
EXP		 Calcium Chloride results in increased expression of IL1B protein
Quercetin inhibits the reaction [Calcium Chloride results in increased expression of IL1B protein]		 CTD PMID:22728078 PMID:36731150 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Itih1 inter-alpha trypsin inhibitor, heavy chain 1 multiple interactions ISO Calcium Chloride promotes the reaction [ITIH1 protein binds to TNFAIP6 protein] CTD PMID:16768462 NCBI chr16:6,122,246...6,136,363
Ensembl chr16:6,122,248...6,136,363 		JBrowse link
G Itih2 inter-alpha-trypsin inhibitor heavy chain 2 multiple interactions ISO Calcium Chloride promotes the reaction [ITIH2 protein binds to TNFAIP6 protein] CTD PMID:16768462 NCBI chr17:68,375,574...68,411,849
Ensembl chr17:68,375,567...68,411,841 		JBrowse link
G Klk8 kallikrein related-peptidase 8 increases activity ISO Calcium Chloride results in increased activity of KLK8 protein CTD PMID:16800733 NCBI chr 1:94,251,803...94,258,646
Ensembl chr 1:94,251,803...94,258,646 		JBrowse link
G Lasp1 LIM and SH3 protein 1 increases expression ISO Calcium Chloride results in increased expression of LASP1 protein CTD PMID:25824407 NCBI chr10:82,795,177...82,835,659
Ensembl chr10:82,795,137...82,943,292 		JBrowse link
G Lrrfip1 LRR binding FLII interacting protein 1 decreases expression ISO Calcium Chloride results in decreased expression of LRRFIP1 protein CTD PMID:25824407 NCBI chr 9:91,592,032...91,720,250
Ensembl chr 9:91,643,197...91,720,250 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions		 EXP Calcium Chloride results in increased phosphorylation of MAPK1 protein
[4-Aminopyridine co-treated with Calcium Chloride] results in increased phosphorylation of MAPK1 protein; typhaneoside inhibits the reaction [[4-Aminopyridine co-treated with Calcium Chloride] results in increased phosphorylation of MAPK1 protein]		 CTD PMID:21215118 PMID:33621091 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases expression
multiple interactions
increases phosphorylation		 ISO
EXP		 Calcium Chloride results in increased expression of MAPK3 protein
[4-Aminopyridine co-treated with Calcium Chloride] results in increased phosphorylation of MAPK3 protein; typhaneoside inhibits the reaction [[4-Aminopyridine co-treated with Calcium Chloride] results in increased phosphorylation of MAPK3 protein]
Calcium Chloride results in increased phosphorylation of MAPK3 protein		 CTD PMID:21215118 PMID:25824407 PMID:33621091 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mmp2 matrix metallopeptidase 2 increases expression
increases activity
multiple interactions		 EXP
ISO		 Calcium Chloride results in increased expression of MMP2 mRNA; Calcium Chloride results in increased expression of MMP2 protein
Calcium Chloride results in increased activity of MMP2 protein
Quercetin inhibits the reaction [Calcium Chloride results in increased activity of MMP2 protein]; Quercetin inhibits the reaction [Calcium Chloride results in increased expression of MMP2 mRNA]; Quercetin inhibits the reaction [Calcium Chloride results in increased expression of MMP2 protein]; resveratrol inhibits the reaction [Calcium Chloride results in increased activity of MMP2 protein]
Calcium Chloride inhibits the reaction [2,3-dihydroxybenzoic acid results in decreased activity of MMP2 protein]; Calcium Chloride inhibits the reaction [Deferoxamine results in decreased activity of MMP2 protein]; Calcium Chloride inhibits the reaction [Ferrichrome results in decreased activity of MMP2 protein]; Calcium Chloride inhibits the reaction [rhodotorulic acid results in decreased activity of MMP2 protein]		 CTD PMID:10086886 PMID:16159824 PMID:20621845 PMID:21530968 PMID:22728078 More... NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression
increases activity
multiple interactions		 EXP
ISO		 Calcium Chloride results in increased expression of MMP9 mRNA; Calcium Chloride results in increased expression of MMP9 protein
Calcium Chloride results in increased activity of MMP9 protein
Quercetin inhibits the reaction [Calcium Chloride results in increased activity of MMP9 protein]; Quercetin inhibits the reaction [Calcium Chloride results in increased expression of MMP9 mRNA]; Quercetin inhibits the reaction [Calcium Chloride results in increased expression of MMP9 protein]; resveratrol inhibits the reaction [Calcium Chloride results in increased activity of MMP9 protein]		 CTD PMID:20621845 PMID:21530968 PMID:22728078 PMID:24337353 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions EXP Calcium Chloride inhibits the reaction [Azoxymethane results in increased expression of MYC mRNA]; Calcium Chloride inhibits the reaction [Azoxymethane results in increased expression of MYC protein] CTD PMID:12189186 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 increases expression
multiple interactions		 ISO Calcium Chloride results in increased expression of NCF1 mRNA; Calcium Chloride results in increased expression of NCF1 protein
Quercetin inhibits the reaction [Calcium Chloride results in increased expression of NCF1 mRNA]; Quercetin inhibits the reaction [Calcium Chloride results in increased expression of NCF1 protein]		 CTD PMID:24337353 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646 		JBrowse link
G Nos1 nitric oxide synthase 1 multiple interactions EXP Calcium Chloride promotes the reaction [NOS1 protein results in increased reduction of Trinitrotoluene] CTD PMID:15223068 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions		 ISO Calcium Chloride results in increased expression of NOS2 mRNA
Quercetin inhibits the reaction [Calcium Chloride results in increased expression of NOS2 mRNA]		 CTD PMID:24337353 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nt5c 5', 3'-nucleotidase, cytosolic increases expression ISO Calcium Chloride results in increased expression of NT5C protein CTD PMID:25824407 NCBI chr10:100,739,591...100,742,276
Ensembl chr10:100,739,588...100,741,954 		JBrowse link
G Nxn nucleoredoxin increases expression ISO Calcium Chloride results in increased expression of NXN protein CTD PMID:25824407 NCBI chr10:61,109,322...61,247,578
Ensembl chr10:61,110,020...61,248,251 		JBrowse link
G Pon1 paraoxonase 1 multiple interactions ISO Calcium Chloride promotes the reaction [PON1 protein results in increased hydrolysis of Paraoxon] CTD PMID:16052486 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360 		JBrowse link
G Postn periostin decreases expression ISO Calcium Chloride results in decreased expression of POSTN protein CTD PMID:25824407 NCBI chr 2:138,527,714...138,559,098
Ensembl chr 2:138,527,696...138,559,099 		JBrowse link
G Ppid peptidylprolyl isomerase D increases expression ISO Calcium Chloride results in increased expression of PPID mRNA; Calcium Chloride results in increased expression of PPID protein CTD PMID:18614807 NCBI chr 2:164,727,803...164,740,168
Ensembl chr 2:164,727,779...164,740,221 		JBrowse link
G Psen2 presenilin 2 increases expression ISO Calcium Chloride results in increased expression of PSEN2 protein CTD PMID:25824407 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174 		JBrowse link
G Rad50 RAD50 double strand break repair protein decreases expression ISO Calcium Chloride results in decreased expression of RAD50 protein CTD PMID:25824407 NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396 		JBrowse link
G Reck reversion-inducing-cysteine-rich protein with kazal motifs increases expression ISO Calcium Chloride results in increased expression of RECK protein CTD PMID:25824407 NCBI chr 5:58,102,961...58,169,516
Ensembl chr 5:58,102,981...58,169,502 		JBrowse link
G S100a13 S100 calcium binding protein A13 multiple interactions ISO [Calcium Chloride co-treated with cuprous chloride] binds to and affects the folding of S100A13 protein; Calcium Chloride binds to and affects the folding of S100A13 protein CTD PMID:16766622 NCBI chr 2:175,999,439...176,005,933 JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression ISO Calcium Chloride results in increased expression of S100A8 mRNA; Calcium Chloride results in increased expression of S100A8 protein CTD PMID:17214633 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643 		JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression ISO Calcium Chloride results in increased expression of S100A9 mRNA; Calcium Chloride results in increased expression of S100A9 protein CTD PMID:17214633 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G Shc1 SHC adaptor protein 1 increases expression ISO Calcium Chloride results in increased expression of SHC1 protein CTD PMID:25824407 NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536 		JBrowse link
G Sod2 superoxide dismutase 2 increases activity
multiple interactions		 ISO Calcium Chloride results in increased activity of SOD2 protein
Quercetin inhibits the reaction [Calcium Chloride results in increased activity of SOD2 protein]		 CTD PMID:24337353 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 decreases expression ISO Calcium Chloride results in decreased expression of STAT6 protein CTD PMID:25824407 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495 		JBrowse link
G Syn1 synapsin I multiple interactions EXP [4-Aminopyridine co-treated with Calcium Chloride] results in increased phosphorylation of SYN1 protein; typhaneoside inhibits the reaction [[4-Aminopyridine co-treated with Calcium Chloride] results in increased phosphorylation of SYN1 protein] CTD PMID:33621091 NCBI chr  X:1,172,208...1,227,400
Ensembl chr  X:1,172,208...1,227,396 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression ISO Calcium Chloride results in decreased expression of TGFB1 protein CTD PMID:25824407 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 decreases expression
multiple interactions		 ISO Calcium Chloride results in decreased expression of TIMP1 mRNA
Quercetin inhibits the reaction [Calcium Chloride results in decreased expression of TIMP1 mRNA]		 CTD PMID:22728078 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression		 ISO
EXP		 Quercetin inhibits the reaction [Calcium Chloride results in increased expression of TNF protein]; resveratrol inhibits the reaction [Calcium Chloride results in increased expression of TNF mRNA]
cordycepin inhibits the reaction [Calcium Chloride results in increased expression of TNF protein]
Calcium Chloride inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of TNF protein]
Calcium Chloride results in increased expression of TNF mRNA; Calcium Chloride results in increased expression of TNF protein		 CTD PMID:21530968 PMID:22728078 PMID:36416909 PMID:36731150 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfaip6 TNF alpha induced protein 6 multiple interactions ISO Calcium Chloride promotes the reaction [ITIH1 protein binds to TNFAIP6 protein]; Calcium Chloride promotes the reaction [ITIH2 protein binds to TNFAIP6 protein] CTD PMID:16768462 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions
increases activity		 ISO
EXP		 Calcium Chloride inhibits the reaction [resiniferatoxin affects the reaction [[Sodium Chloride co-treated with benzamil] results in increased activity of TRPV1 protein]]; Ionomycin promotes the reaction [Calcium Chloride inhibits the reaction [resiniferatoxin affects the reaction [[Sodium Chloride co-treated with benzamil] results in increased activity of TRPV1 protein]]]
Ionomycin inhibits the reaction [Calcium Chloride results in increased activity of TRPV1 protein]; N-(3-methoxyphenyl)-4-chlorocinnamanilide inhibits the reaction [Calcium Chloride results in increased activity of TRPV1 protein]; resiniferatoxin promotes the reaction [Calcium Chloride results in increased activity of TRPV1 protein]		 CTD PMID:19553475 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513 		JBrowse link
G Ube3b ubiquitin protein ligase E3B multiple interactions ISO Calcium Chloride inhibits the reaction [CALM3 protein binds to and results in decreased activity of UBE3B protein] CTD PMID:28003368 NCBI chr12:42,183,756...42,230,094
Ensembl chr12:42,183,760...42,230,094 		JBrowse link
G Uqcrfs1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 decreases phosphorylation
multiple interactions		 EXP Calcium Chloride results in decreased phosphorylation of UQCRFS1 protein
[oxophenylarsine co-treated with Calcium Chloride] results in decreased phosphorylation of UQCRFS1 protein; [tert-Butylhydroperoxide co-treated with Calcium Chloride] results in decreased phosphorylation of UQCRFS1 protein; Cyclosporine inhibits the reaction [[oxophenylarsine co-treated with Calcium Chloride] results in decreased phosphorylation of UQCRFS1 protein]; Cyclosporine inhibits the reaction [[tert-Butylhydroperoxide co-treated with Calcium Chloride] results in decreased phosphorylation of UQCRFS1 protein]		 CTD PMID:16023995 NCBI chr17:33,977,908...33,982,478
Ensembl chr17:33,977,921...33,982,479 		JBrowse link
G Vegfa vascular endothelial growth factor A increases expression
multiple interactions		 ISO Calcium Chloride results in increased expression of VEGFA mRNA
resveratrol inhibits the reaction [Calcium Chloride results in increased expression of VEGFA mRNA]		 CTD PMID:21530968 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
calcium dihydroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alpl alkaline phosphatase, biomineralization associated increases expression ISO Calcium Hydroxide results in increased expression of ALPL mRNA CTD PMID:22083529 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446 		JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression ISO Calcium Hydroxide results in increased expression of COL1A1 mRNA CTD PMID:22083529 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Esr1 estrogen receptor 1 increases expression ISO Calcium Hydroxide results in increased expression of ESR1 mRNA CTD PMID:22083529 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Polg DNA polymerase gamma, catalytic subunit affects expression ISO Calcium Hydroxide affects the expression of POLG mRNA CTD PMID:30615914 NCBI chr 1:133,382,764...133,399,578
Ensembl chr 1:133,382,766...133,398,567 		JBrowse link
G Polg2 DNA polymerase gamma 2, accessory subunit affects expression ISO Calcium Hydroxide affects the expression of POLG2 mRNA CTD PMID:30615914 NCBI chr10:91,712,586...91,723,008
Ensembl chr10:91,712,586...91,723,008 		JBrowse link
G Tfam transcription factor A, mitochondrial affects expression ISO Calcium Hydroxide affects the expression of TFAM mRNA CTD PMID:30615914 NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 increases expression ISO Calcium Hydroxide results in increased expression of TRPV1 mRNA CTD PMID:22083529 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513 		JBrowse link
calcium phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression ISO calcium phosphate results in increased expression of CXCL10 protein CTD PMID:14600836 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression ISO calcium phosphate results in increased expression of CXCL12 protein CTD PMID:14600836 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
calcium silicate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing increases expression ISO calcium silicate results in increased expression of ADIPOQ mRNA CTD PMID:29279043 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Alb albumin increases expression ISO calcium silicate results in increased expression of ALB mRNA CTD PMID:29279043 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO [Zinc binds to calcium silicate] which results in increased expression of ALPL mRNA CTD PMID:23483914 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446 		JBrowse link
G Ambp alpha-1-microglobulin/bikunin precursor increases expression ISO calcium silicate results in increased expression of AMBP mRNA CTD PMID:29279043 NCBI chr 5:76,568,094...76,578,416
Ensembl chr 5:76,568,094...76,578,331 		JBrowse link
G Ankrd39 ankyrin repeat domain 39 increases expression ISO calcium silicate results in increased expression of ANKRD39 mRNA CTD PMID:29279043 NCBI chr 9:38,780,291...38,790,177
Ensembl chr 9:38,781,785...38,790,201 		JBrowse link
G Aoah acyloxyacyl hydrolase increases expression ISO calcium silicate results in increased expression of AOAH mRNA CTD PMID:29279043 NCBI chr17:43,808,110...44,049,458
Ensembl chr17:43,809,638...44,049,148 		JBrowse link
G Apoa2 apolipoprotein A2 increases expression ISO calcium silicate results in increased expression of APOA2 mRNA CTD PMID:29279043 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355 		JBrowse link
G Apob apolipoprotein B increases expression ISO calcium silicate results in increased expression of APOB mRNA CTD PMID:29279043 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497 		JBrowse link
G Armcx2 armadillo repeat containing, X-linked 2 decreases expression ISO calcium silicate results in decreased expression of ARMCX2 mRNA CTD PMID:29279043 NCBI chr  X:97,980,662...97,985,523
Ensembl chr  X:97,980,660...97,985,552 		JBrowse link
G Aste1 asteroid homolog 1 increases expression ISO calcium silicate results in increased expression of ASTE1 mRNA CTD PMID:29279043 NCBI chr 8:106,026,570...106,044,694
Ensembl chr 8:106,026,515...106,044,430 		JBrowse link
G Bcl9l BCL9 like decreases expression ISO calcium silicate results in decreased expression of BCL9L mRNA CTD PMID:29279043 NCBI chr 8:44,811,977...44,840,611
Ensembl chr 8:44,811,977...44,840,611 		JBrowse link
G Bgn biglycan decreases expression ISO calcium silicate results in decreased expression of BGN mRNA CTD PMID:29279043 NCBI chr  X:151,197,296...151,209,458
Ensembl chr  X:151,197,273...151,209,461 		JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 increases expression ISO calcium silicate results in increased expression of BMAL1 mRNA CTD PMID:29279043 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231 		JBrowse link
G Bptf bromodomain PHD finger transcription factor decreases expression ISO calcium silicate results in decreased expression of BPTF mRNA CTD PMID:29279043 NCBI chr10:91,980,279...92,082,731
Ensembl chr10:91,982,758...92,082,769 		JBrowse link
G Capns1 calpain, small subunit 1 decreases expression ISO calcium silicate results in decreased expression of CAPNS1 mRNA CTD PMID:29279043 NCBI chr 1:85,444,613...85,454,861
Ensembl chr 1:85,444,608...85,454,795 		JBrowse link
G Car3 carbonic anhydrase 3 increases expression ISO calcium silicate results in increased expression of CAR3 mRNA CTD PMID:29279043 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression EXP calcium silicate results in increased expression of CCL2 protein CTD PMID:16601788 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression EXP calcium silicate results in increased expression of CCL3 protein CTD PMID:16601788 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Chrnb3 cholinergic receptor nicotinic beta 3 subunit increases expression ISO calcium silicate results in increased expression of CHRNB3 mRNA CTD PMID:29279043 NCBI chr16:64,713,438...64,751,360
Ensembl chr16:64,714,169...64,751,360 		JBrowse link
G Clca1 chloride channel accessory 1 increases expression ISO calcium silicate results in increased expression of CLCA1 mRNA CTD PMID:29279043 NCBI chr 2:233,938,677...233,964,369
Ensembl chr 2:233,938,677...233,964,369 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO [Zinc binds to calcium silicate] which results in increased expression of COL1A1 mRNA CTD PMID:23483914 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Cybb cytochrome b-245 beta chain increases expression ISO calcium silicate results in increased expression of CYBB mRNA CTD PMID:29279043 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586 		JBrowse link
G Ddo D-aspartate oxidase decreases expression ISO calcium silicate results in decreased expression of DDO mRNA CTD PMID:29279043 NCBI chr20:44,090,823...44,109,962
Ensembl chr20:44,090,914...44,133,095 		JBrowse link
G Dhx35 DEAH-box helicase 35 increases expression ISO calcium silicate results in increased expression of DHX35 mRNA CTD PMID:29279043 NCBI chr 3:147,450,178...147,507,473
Ensembl chr 3:147,450,163...147,507,451 		JBrowse link
G Dpp10 dipeptidyl peptidase like 10 increases expression ISO calcium silicate results in increased expression of DPP10 mRNA CTD PMID:29279043 NCBI chr13:34,584,420...36,269,292
Ensembl chr13:34,595,868...36,269,292 		JBrowse link
G Egfr epidermal growth factor receptor increases activity ISO calcium silicate results in increased activity of EGFR protein CTD PMID:21762757 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Epb42 erythrocyte membrane protein band 4.2 increases expression ISO calcium silicate results in increased expression of EPB42 mRNA CTD PMID:29279043 NCBI chr 3:107,979,709...107,997,932
Ensembl chr 3:107,979,713...107,997,932 		JBrowse link
G Fam83h family with sequence similarity 83, member H increases expression ISO calcium silicate results in increased expression of FAM83H mRNA CTD PMID:29279043 NCBI chr 7:107,716,431...107,724,619
Ensembl chr 7:107,716,431...107,728,672 		JBrowse link
G Fgg fibrinogen gamma chain increases expression ISO calcium silicate results in increased expression of FGG mRNA CTD PMID:29279043 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322 		JBrowse link
G Fgl1 fibrinogen-like 1 increases expression ISO calcium silicate results in increased expression of FGL1 mRNA CTD PMID:29279043 NCBI chr16:51,120,652...51,150,907
Ensembl chr16:51,120,694...51,151,093 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 multiple interactions
increases secretion		 ISO RTKI cpd inhibits the reaction [calcium silicate results in increased secretion of FLT1 protein] CTD PMID:21762757 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626 		JBrowse link
G Gc GC, vitamin D binding protein increases expression ISO calcium silicate results in increased expression of GC mRNA CTD PMID:29279043 NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567 		JBrowse link
G Glt8d1 glycosyltransferase 8 domain containing 1 increases expression ISO calcium silicate results in increased expression of GLT8D1 mRNA CTD PMID:29279043 NCBI chr16:6,192,269...6,207,227
Ensembl chr16:6,192,300...6,207,229 		JBrowse link
G Gsr glutathione-disulfide reductase increases activity EXP calcium silicate results in increased activity of GSR protein CTD PMID:16601788 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G H1f2 H1.2 linker histone, cluster member decreases expression ISO calcium silicate results in decreased expression of H1F2 mRNA CTD PMID:29279043 NCBI chr17:41,391,106...41,392,597
Ensembl chr17:41,388,477...41,392,635 		JBrowse link
G Hlf HLF transcription factor, PAR bZIP family member decreases expression ISO calcium silicate results in decreased expression of HLF mRNA CTD PMID:29279043 NCBI chr10:75,154,244...75,211,884
Ensembl chr10:75,154,507...75,211,935 		JBrowse link
G Hmg20b high mobility group 20 B decreases expression ISO calcium silicate results in decreased expression of HMG20B mRNA CTD PMID:29279043 NCBI chr 7:8,368,934...8,373,650
Ensembl chr 7:8,368,990...8,373,640 		JBrowse link
G Hpcal1 hippocalcin-like 1 increases expression ISO calcium silicate results in increased expression of HPCAL1 mRNA CTD PMID:29279043 NCBI chr 6:40,478,206...40,584,721
Ensembl chr 6:40,478,208...40,584,687 		JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO [Zinc binds to calcium silicate] which results in increased expression of IGF1 mRNA CTD PMID:23483914 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases secretion		 ISO Acetylcysteine inhibits the reaction [calcium silicate results in increased secretion of IL6 protein]; prolinedithiocarbamate inhibits the reaction [calcium silicate results in increased secretion of IL6 protein] CTD PMID:21762757 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Ipmk inositol polyphosphate multikinase decreases expression ISO calcium silicate results in decreased expression of IPMK mRNA CTD PMID:29279043 NCBI chr20:17,216,988...17,251,675
Ensembl chr20:17,218,037...17,251,705 		JBrowse link
G Kank4 KN motif and ankyrin repeat domains 4 decreases expression ISO calcium silicate results in decreased expression of KANK4 mRNA CTD PMID:29279043 NCBI chr 5:113,401,491...113,465,526
Ensembl chr 5:113,402,468...113,465,555 		JBrowse link
G Kat8 lysine acetyltransferase 8 increases expression ISO calcium silicate results in increased expression of KAT8 mRNA CTD PMID:29279043 NCBI chr 1:182,524,355...182,536,638
Ensembl chr 1:182,515,327...182,536,633 		JBrowse link
G Kcnmb4 potassium calcium-activated channel subfamily M regulatory beta subunit 4 decreases expression ISO calcium silicate results in decreased expression of KCNMB4 mRNA CTD PMID:29279043 NCBI chr 7:52,066,145...52,119,098
Ensembl chr 7:52,066,136...52,119,278 		JBrowse link
G Kdr kinase insert domain receptor increases secretion ISO calcium silicate results in increased secretion of KDR protein CTD PMID:21762757 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Klhl2 kelch-like family member 2 decreases expression ISO calcium silicate results in decreased expression of KLHL2 mRNA CTD PMID:29279043 NCBI chr16:24,860,744...24,973,348
Ensembl chr16:24,860,667...24,973,341 		JBrowse link
G Ldb1 LIM domain binding 1 decreases expression ISO calcium silicate results in decreased expression of LDB1 mRNA CTD PMID:29279043 NCBI chr 1:244,864,168...244,890,007
Ensembl chr 1:244,877,173...244,890,013 		JBrowse link
G Lmo7 LIM domain 7 decreases expression ISO calcium silicate results in decreased expression of LMO7 mRNA CTD PMID:29279043 NCBI chr15:78,566,999...78,769,833
Ensembl chr15:78,567,023...78,769,783 		JBrowse link
G Ltn1 listerin E3 ubiquitin protein ligase 1 decreases expression ISO calcium silicate results in decreased expression of LTN1 mRNA CTD PMID:29279043 NCBI chr11:26,603,903...26,660,871
Ensembl chr11:26,603,903...26,660,886 		JBrowse link
G Malt1 MALT1 paracaspase increases expression ISO calcium silicate results in increased expression of MALT1 mRNA CTD PMID:29279043 NCBI chr18:58,942,282...58,996,318
Ensembl chr18:58,942,299...58,994,260 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation		 ISO RTKI cpd inhibits the reaction [calcium silicate results in increased phosphorylation of MAPK1 protein] CTD PMID:21762757 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions		 ISO calcium silicate results in increased phosphorylation of MAPK3 protein
RTKI cpd inhibits the reaction [calcium silicate results in increased phosphorylation of MAPK3 protein]		 CTD PMID:21762757 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Matk megakaryocyte-associated tyrosine kinase increases expression ISO calcium silicate results in increased expression of MATK mRNA CTD PMID:29279043 NCBI chr 7:8,456,990...8,465,947
Ensembl chr 7:8,456,998...8,462,022 		JBrowse link
G Mettl8 methyltransferase 8, tRNA N3-cytidine increases expression ISO calcium silicate results in increased expression of METTL8 mRNA CTD PMID:29279043 NCBI chr 3:55,731,453...55,863,652
Ensembl chr 3:55,770,167...55,863,676 		JBrowse link
G Mfsd11 major facilitator superfamily domain containing 11 decreases expression ISO calcium silicate results in decreased expression of MFSD11 mRNA CTD PMID:29279043 NCBI chr10:102,055,516...102,075,064
Ensembl chr10:102,056,051...102,075,064 		JBrowse link
G Mup18 major urinary protein 18 increases expression ISO calcium silicate results in increased expression of MUP18 mRNA CTD PMID:29279043 NCBI chr 5:74,986,813...74,990,071
Ensembl chr 5:74,842,319...75,061,474 		JBrowse link
G Naa38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit increases expression ISO calcium silicate results in increased expression of NAA38 mRNA CTD PMID:29279043 NCBI chr10:54,117,754...54,118,913
Ensembl chr10:54,117,163...54,119,494 		JBrowse link
G Nanp N-acetylneuraminic acid phosphatase decreases expression ISO calcium silicate results in decreased expression of NANP mRNA CTD PMID:29279043 NCBI chr 3:139,826,549...139,841,655
Ensembl chr 3:139,826,549...139,841,648 		JBrowse link
G Nop53 NOP53 ribosome biogenesis factor increases expression ISO calcium silicate results in increased expression of NOP53 mRNA CTD PMID:29279043 NCBI chr 1:76,629,084...76,636,902
Ensembl chr 1:76,629,069...76,636,902 		JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 decreases expression ISO calcium silicate results in decreased expression of NR1D1 mRNA CTD PMID:29279043 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705 		JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 decreases expression ISO calcium silicate results in decreased expression of NR1D2 mRNA CTD PMID:29279043 NCBI chr15:7,524,257...7,550,553
Ensembl chr15:7,524,257...7,550,553 		JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 increases expression ISO calcium silicate results in increased expression of NTRK3 mRNA CTD PMID:29279043 NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286 		JBrowse link
G Oaf out at first homolog increases expression ISO calcium silicate results in increased expression of OAF mRNA CTD PMID:29279043 NCBI chr 8:43,594,362...43,612,334
Ensembl chr 8:43,594,363...43,612,334 		JBrowse link
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 increases expression ISO calcium silicate results in increased expression of ORMDL2 mRNA CTD PMID:29279043 NCBI chr 7:1,247,869...1,250,999
Ensembl chr 7:1,246,479...1,250,907 		JBrowse link
G Osbpl3 oxysterol binding protein-like 3 increases expression ISO calcium silicate results in increased expression of OSBPL3 mRNA CTD PMID:29279043 NCBI chr 4:79,346,583...79,523,523
Ensembl chr 4:79,350,349...79,523,393 		JBrowse link
G P4ha2 prolyl 4-hydroxylase subunit alpha 2 decreases expression ISO calcium silicate results in decreased expression of P4HA2 mRNA CTD PMID:29279043 NCBI chr10:38,243,136...38,271,983
Ensembl chr10:38,243,139...38,287,314 		JBrowse link
G Pag1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 decreases expression ISO calcium silicate results in decreased expression of PAG1 mRNA CTD PMID:29279043 NCBI chr 2:91,935,378...92,076,937
Ensembl chr 2:92,057,216...92,069,849 		JBrowse link
G Per3 period circadian regulator 3 decreases expression ISO calcium silicate results in decreased expression of PER3 mRNA CTD PMID:29279043 NCBI chr 5:161,460,228...161,495,404
Ensembl chr 5:161,459,533...161,495,607 		JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 decreases expression ISO calcium silicate results in decreased expression of PFKFB3 mRNA CTD PMID:29279043 NCBI chr17:66,983,629...67,064,702
Ensembl chr17:66,983,686...67,063,125 		JBrowse link
G Phgdh phosphoglycerate dehydrogenase increases expression ISO calcium silicate results in increased expression of PHGDH mRNA CTD PMID:29279043 NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma increases expression ISO calcium silicate results in increased expression of PIK3CG mRNA CTD PMID:29279043 NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043 		JBrowse link
G Plaa phospholipase A2, activating protein increases expression ISO calcium silicate results in increased expression of PLAA mRNA CTD PMID:29279043 NCBI chr 5:109,428,600...109,460,373
Ensembl chr 5:109,428,265...109,460,282 		JBrowse link
G Pmm2 phosphomannomutase 2 increases expression ISO calcium silicate results in increased expression of PMM2 mRNA CTD PMID:29279043 NCBI chr10:6,961,521...6,982,913
Ensembl chr10:6,961,709...6,983,098 		JBrowse link
G Prpf19 pre-mRNA processing factor 19 decreases expression ISO calcium silicate results in decreased expression of PRPF19 mRNA CTD PMID:29279043 NCBI chr 1:207,541,582...207,552,664
Ensembl chr 1:207,541,595...207,552,662 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases localization ISO calcium silicate results in increased localization of RELA protein CTD PMID:21762757 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Rhobtb2 Rho-related BTB domain containing 2 increases expression ISO calcium silicate results in increased expression of RHOBTB2 mRNA CTD PMID:29279043 NCBI chr15:44,868,251...44,888,436
Ensembl chr15:44,870,376...44,888,651 		JBrowse link
G Rnmt RNA (guanine-7-) methyltransferase decreases expression ISO calcium silicate results in decreased expression of RNMT mRNA CTD PMID:29279043 NCBI chr18:61,886,230...61,909,775
Ensembl chr18:61,886,292...61,909,775 		JBrowse link
G Rps25 ribosomal protein s25 decreases expression ISO calcium silicate results in decreased expression of RPS25 mRNA CTD PMID:29279043 NCBI chr 8:44,733,623...44,735,999
Ensembl chr 8:44,733,029...44,737,271
Ensembl chr 8:44,733,029...44,737,271 		JBrowse link
G Rwdd3 RWD domain containing 3 increases expression ISO calcium silicate results in increased expression of RWDD3 mRNA CTD PMID:29279043 NCBI chr 2:209,233,622...209,254,842
Ensembl chr 2:209,233,622...209,248,853 		JBrowse link
G Scgb3a1 secretoglobin, family 3A, member 1 increases expression ISO calcium silicate results in increased expression of SCGB3A1 mRNA CTD PMID:29279043 NCBI chr10:33,968,059...33,969,366
Ensembl chr10:33,968,059...33,969,476 		JBrowse link
G Schip1 schwannomin interacting protein 1 decreases expression ISO calcium silicate results in decreased expression of SCHIP1 mRNA CTD PMID:29279043 NCBI chr 2:152,127,171...152,888,587
Ensembl chr 2:152,126,953...152,888,585 		JBrowse link
G Sgms1 sphingomyelin synthase 1 decreases expression ISO calcium silicate results in decreased expression of SGMS1 mRNA CTD PMID:29279043 NCBI chr 1:229,996,673...230,259,591
Ensembl chr 1:229,998,119...230,259,603 		JBrowse link
G Slc1a5 solute carrier family 1 member 5 decreases expression ISO calcium silicate results in decreased expression of SLC1A5 mRNA CTD PMID:29279043 NCBI chr 1:77,456,849...77,470,952
Ensembl chr 1:77,456,694...77,470,952 		JBrowse link
G Slc38a10 solute carrier family 38, member 10 decreases expression ISO calcium silicate results in decreased expression of SLC38A10 mRNA CTD PMID:29279043 NCBI chr10:105,386,836...105,436,636
Ensembl chr10:105,386,836...105,436,636 		JBrowse link
G Slc6a13 solute carrier family 6 member 13 increases expression ISO calcium silicate results in increased expression of SLC6A13 mRNA CTD PMID:29279043 NCBI chr 4:154,539,246...154,577,784
Ensembl chr 4:154,540,468...154,576,152 		JBrowse link
G Snord61 small nucleolar RNA, C/D box 61 decreases expression ISO calcium silicate results in decreased expression of SNORD61 mRNA CTD PMID:29279043 NCBI chr  X:135,313,247...135,313,319
Ensembl chr  X:135,313,247...135,313,319 		JBrowse link
G Sod1 superoxide dismutase 1 decreases activity EXP calcium silicate results in decreased activity of SOD1 protein CTD PMID:16601788 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Ssbp3 single stranded DNA binding protein 3 decreases expression ISO calcium silicate results in decreased expression of SSBP3 mRNA CTD PMID:29279043 NCBI chr 5:121,691,370...121,828,035
Ensembl chr 5:121,691,393...121,827,992 		JBrowse link
G Taf10 TATA-box binding protein associated factor 10 increases expression ISO calcium silicate results in increased expression of TAF10 mRNA CTD PMID:29279043 NCBI chr 1:160,095,108...160,096,401
Ensembl chr 1:160,095,108...160,096,376 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [Zinc binds to calcium silicate] which results in increased expression of TGFB1 mRNA CTD PMID:23483914 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Them7 thioesterase superfamily member 7 increases expression ISO calcium silicate results in increased expression of THEM7 mRNA CTD PMID:29279043 NCBI chr 3:91,666,144...91,834,783
Ensembl chr 3:91,666,152...91,834,783 		JBrowse link
G Tmem171 transmembrane protein 171 increases expression ISO calcium silicate results in increased expression of TMEM171 mRNA CTD PMID:29279043 NCBI chr 2:30,035,278...30,045,996
Ensembl chr 2:30,035,278...30,045,049 		JBrowse link
G Tmem54 transmembrane protein 54 increases expression ISO calcium silicate results in increased expression of TMEM54 mRNA CTD PMID:29279043 NCBI chr 5:141,449,191...141,455,683
Ensembl chr 5:141,449,191...141,455,682 		JBrowse link
G Tmod4 tropomodulin 4 increases expression ISO calcium silicate results in increased expression of TMOD4 mRNA CTD PMID:29279043 NCBI chr 2:182,695,709...182,700,540
Ensembl chr 2:182,695,709...182,700,540 		JBrowse link
G Tp53 tumor protein p53 increases expression ISO calcium silicate results in increased expression of TRP53 mRNA CTD PMID:29279043 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tuba1c tubulin, alpha 1C decreases expression ISO calcium silicate results in decreased expression of TUBA1C mRNA CTD PMID:29279043 NCBI chr 7:130,192,050...130,199,655
Ensembl chr 7:130,192,016...130,199,647
Ensembl chr  X:130,192,016...130,199,647 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
increases secretion		 ISO RTKI cpd inhibits the reaction [calcium silicate results in increased secretion of VEGFA protein] CTD PMID:21762757 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vps35l VPS35 endosomal protein sorting factor like increases expression ISO calcium silicate results in increased expression of VPS35L mRNA CTD PMID:29279043 NCBI chr 1:173,076,219...173,179,663
Ensembl chr 1:173,076,099...173,180,610 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A decreases expression ISO calcium silicate results in decreased expression of ZC3H12A mRNA CTD PMID:29279043 NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351 		JBrowse link
G Zmynd8 zinc finger, MYND-type containing 8 increases expression ISO calcium silicate results in increased expression of ZMYND8 mRNA CTD PMID:29279043 NCBI chr 3:154,528,917...154,629,532
Ensembl chr 3:154,529,043...154,628,463 		JBrowse link
tricalcium bis(phosphate) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnm1l dynamin 1-like increases expression ISO tricalcium phosphate results in increased expression of DNM1L protein CTD PMID:37678662 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482 		JBrowse link
G Hmox1 heme oxygenase 1 decreases expression ISO tricalcium phosphate results in decreased expression of HMOX1 protein CTD PMID:37678662 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions
affects localization		 ISO Acetylcysteine inhibits the reaction [tricalcium phosphate affects the localization of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [tricalcium phosphate results in increased expression of MAP1LC3B protein] CTD PMID:37678662 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
Ensembl chr16:49,665,791...49,677,690 		JBrowse link
G Mfn2 mitofusin 2 decreases expression ISO tricalcium phosphate results in decreased expression of MFN2 protein CTD PMID:37678662 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Mlkl mixed lineage kinase domain like pseudokinase multiple interactions
increases phosphorylation		 ISO Acetylcysteine inhibits the reaction [tricalcium phosphate results in increased phosphorylation of MLKL protein]; N-(4-(N-(3-methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophene-2-yl)acrylamide inhibits the reaction [tricalcium phosphate results in increased phosphorylation of MLKL protein]; necrostatin-1 inhibits the reaction [tricalcium phosphate results in increased phosphorylation of MLKL protein] CTD PMID:37678662 NCBI chr19:39,277,526...39,304,555
Ensembl chr19:39,276,785...39,304,502 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 decreases expression ISO tricalcium phosphate results in decreased expression of NFE2L2 protein CTD PMID:37678662 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression ISO tricalcium phosphate results in decreased expression of NQO1 protein CTD PMID:37678662 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Pink1 PTEN induced kinase 1 multiple interactions ISO Acetylcysteine inhibits the reaction [tricalcium phosphate results in increased expression of PINK1 protein]; tricalcium phosphate results in increased expression of and results in increased localization of PINK1 protein CTD PMID:37678662 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 increases phosphorylation
multiple interactions		 ISO tricalcium phosphate results in increased phosphorylation of RIPK1 protein
Acetylcysteine inhibits the reaction [tricalcium phosphate results in increased phosphorylation of RIPK1 protein]; N-(4-(N-(3-methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophene-2-yl)acrylamide inhibits the reaction [tricalcium phosphate results in increased phosphorylation of RIPK1 protein]; necrostatin-1 inhibits the reaction [tricalcium phosphate results in increased phosphorylation of RIPK1 protein]		 CTD PMID:37678662 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824 		JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 multiple interactions
increases phosphorylation		 ISO Acetylcysteine inhibits the reaction [tricalcium phosphate results in increased phosphorylation of RIPK3 protein]; N-(4-(N-(3-methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophene-2-yl)acrylamide inhibits the reaction [tricalcium phosphate results in increased phosphorylation of RIPK3 protein]; necrostatin-1 inhibits the reaction [tricalcium phosphate results in increased phosphorylation of RIPK3 protein] CTD PMID:37678662 NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121 		JBrowse link
G Sqstm1 sequestosome 1 decreases expression
multiple interactions		 ISO tricalcium phosphate results in decreased expression of SQSTM1 protein
Acetylcysteine inhibits the reaction [tricalcium phosphate results in decreased expression of SQSTM1 protein]		 CTD PMID:37678662 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Txn1 thioredoxin 1 decreases expression ISO tricalcium phosphate results in decreased expression of TXN1 protein CTD PMID:37678662 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629 		JBrowse link
G Txnip thioredoxin interacting protein increases expression ISO tricalcium phosphate results in increased expression of TXNIP protein CTD PMID:37678662 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    chemical entity 19872
      chemical substance 14394
        mineral 4324
          mineral nutrient 510
            inorganic calcium salt 199
              Calcium hypochlorite 0
              calcium carbonate + 7
              calcium dichloride + 83
              calcium difluoride + 0
              calcium hydroxide + 7
              calcium phosphate + 15
              calcium silicate 100
              calcium sulfate + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  group 19825
                    polyatomic entity 19824
                      heteroatomic molecular entity 19781
                        salt 16284
                          inorganic salt 15549
                            inorganic calcium salt 199
                              Calcium hypochlorite 0
                              calcium carbonate + 7
                              calcium dichloride + 83
                              calcium difluoride + 0
                              calcium hydroxide + 7
                              calcium phosphate + 15
                              calcium silicate 100
                              calcium sulfate + 0
paths to the root