3-chloropropane-1,2-diol - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	3-chloropropane-1,2-diol	go back to main search page
Accession:	CHEBI:18721	browse the term
Definition:	A chloropropane-1,2-diol that is propane-1,2-diol substituted by a chloro group at position 3.
Synonyms:	related_synonym:	(RS)-3-chloro-1,2-propanediol; 1-chloro-2,3-propanediol; 3-Monochloro-1,2-propanediol; Formula=C3H7ClO2; InChI=1S/C3H7ClO2/c4-1-3(6)2-5/h3,5-6H,1-2H2; InChIKey=SSZWWUDQMAHNAQ-UHFFFAOYSA-N; SMILES=OCC(O)CCl; alpha-chlorohydrin; chlorodeoxyglycerol
	xref:	Beilstein:635684; CAS:96-24-2; Gmelin:68752; KEGG:C18676
	xref_mesh:	MESH:D000517
	xref:	PPDB:1231; UM-BBD_compID:c0078

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Genes (1806)

3-chloropropane-1,2-diol

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

RIKEN cDNA 1110059G10 gene

decreases expression
increases expression

alpha-Chlorohydrin results in decreased expression of RGD1311745 protein
alpha-Chlorohydrin analog results in increased expression of RGD1311745 protein

PMID:26072098 PMID:26597043

NCBI chr 9:122,774,154...122,780,065
Ensembl chr 9:122,774,154...122,780,065

G

RIKEN cDNA 4931406C07 gene

decreases expression

alpha-Chlorohydrin results in decreased expression of C8H11ORF54 protein

NCBI chr 9:15,194,633...15,217,836
Ensembl chr 9:15,194,633...15,217,744

G

RIKEN cDNA 5031439G07 gene

increases expression

alpha-Chlorohydrin results in increased expression of KIAA0930 mRNA

NCBI chr15:84,828,137...84,872,503
Ensembl chr15:84,828,137...84,872,752

G

alpha-2-macroglobulin

decreases expression

alpha-Chlorohydrin results in decreased expression of A2M mRNA

NCBI chr 6:121,612,920...121,656,197
Ensembl chr 6:121,612,335...121,656,186

G

arylacetamide deacetylase

increases expression

alpha-Chlorohydrin results in increased expression of AADAC mRNA

NCBI chr 3:59,939,209...59,947,578
Ensembl chr 3:59,933,138...59,947,581

G

alpha- and gamma-adaptin binding protein

increases expression

alpha-Chlorohydrin results in increased expression of AAGAB protein

NCBI chr 9:63,509,897...63,551,872
Ensembl chr 9:63,509,942...63,551,870

G

alanyl-tRNA synthetase 1

increases expression

alpha-Chlorohydrin results in increased expression of AARS1 protein

NCBI chr 8:111,759,781...111,784,237
Ensembl chr 8:111,759,776...111,784,296

G

alanyl-tRNA synthetase 2, mitochondrial

increases expression

alpha-Chlorohydrin results in increased expression of AARS2 protein

NCBI chr17:45,817,473...45,831,769
Ensembl chr17:45,817,767...45,831,769

G

aminoadipate-semialdehyde synthase

decreases expression

alpha-Chlorohydrin analog results in decreased expression of AASS protein; alpha-Chlorohydrin results in decreased expression of AASS protein

PMID:26597043 PMID:34915118

NCBI chr 6:23,072,172...23,132,985
Ensembl chr 6:23,072,172...23,132,985

G

4-aminobutyrate aminotransferase

increases expression

alpha-Chlorohydrin results in increased expression of ABAT mRNA

NCBI chr16:8,331,293...8,439,432
Ensembl chr16:8,331,293...8,439,432

G

ATP-binding cassette, sub-family A member 2

decreases expression

alpha-Chlorohydrin results in decreased expression of ABCA2 protein

NCBI chr 2:25,318,611...25,338,556
Ensembl chr 2:25,318,715...25,338,552

G

ATP-binding cassette, sub-family A member 3

increases expression

alpha-Chlorohydrin results in increased expression of ABCA3 mRNA

NCBI chr17:24,570,997...24,629,178
Ensembl chr17:24,570,924...24,629,175

G

ATP-binding cassette, sub-family B member 1A

decreases expression
increases expression

alpha-Chlorohydrin results in decreased expression of ABCB1 protein
alpha-Chlorohydrin results in increased expression of ABCB1A protein

PMID:17803981 PMID:34915118

NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575

G

ATP-binding cassette, sub-family B member 6

decreases expression

alpha-Chlorohydrin results in decreased expression of ABCB6 protein

NCBI chr 1:75,148,284...75,157,066
Ensembl chr 1:75,148,361...75,157,036

G

ATP-binding cassette, sub-family member 2

increases expression

alpha-Chlorohydrin results in increased expression of ABCC2 protein

NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179

G

ATP-binding cassette, sub-family C member 3

increases expression

alpha-Chlorohydrin results in increased expression of ABCC3 protein

NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823

G

ATP-binding cassette, sub-family C member 4

increases expression

alpha-Chlorohydrin results in increased expression of ABCC4 mRNA; alpha-Chlorohydrin results in increased expression of ABCC4 protein

PMID:28522335 PMID:34915118

NCBI chr14:118,720,104...118,945,475
Ensembl chr14:118,720,104...118,943,631

G

ATP-binding cassette, sub-family D member 2

decreases expression

alpha-Chlorohydrin results in decreased expression of ABCD2 mRNA

NCBI chr15:91,029,874...91,076,013
Ensembl chr15:91,030,074...91,076,002

G

ATP-binding cassette, sub-family F member 1

increases expression

alpha-Chlorohydrin results in increased expression of ABCF1 protein

NCBI chr17:36,267,711...36,280,642
Ensembl chr17:36,267,711...36,280,653

G

ATP-binding cassette, sub-family F member 3

decreases expression

alpha-Chlorohydrin analog results in decreased expression of ABCF3 protein; alpha-Chlorohydrin results in decreased expression of ABCF3 protein

NCBI chr16:20,367,309...20,380,357
Ensembl chr16:20,367,327...20,380,129

G

ATP binding cassette subfamily G member 1

decreases expression

alpha-Chlorohydrin results in decreased expression of ABCG1 mRNA

NCBI chr17:31,276,668...31,336,958
Ensembl chr17:31,276,649...31,336,962

G

abhydrolase domain containing 13

increases expression

alpha-Chlorohydrin results in increased expression of ABHD13 protein

NCBI chr 8:10,027,717...10,042,155
Ensembl chr 8:10,027,707...10,042,155

G

abhydrolase domain containing 14A

decreases expression

alpha-Chlorohydrin results in decreased expression of ABHD14A protein

NCBI chr 9:106,317,250...106,328,402
Ensembl chr 9:106,317,253...106,324,877

G

abhydrolase domain containing 17C

increases expression

alpha-Chlorohydrin results in increased expression of ABHD17C mRNA

NCBI chr 7:83,758,564...83,801,101
Ensembl chr 7:83,758,564...83,801,101

G

abhydrolase domain containing 2

increases expression

alpha-Chlorohydrin results in increased expression of ABHD2 mRNA

NCBI chr 7:78,923,002...79,015,257
Ensembl chr 7:78,922,947...79,015,256

G

abhydrolase domain containing 4

increases expression

alpha-Chlorohydrin results in increased expression of ABHD4 protein

NCBI chr14:54,491,586...54,506,626
Ensembl chr14:54,491,645...54,508,094

G

abhydrolase domain containing 8

decreases expression

alpha-Chlorohydrin results in decreased expression of ABHD8 mRNA

NCBI chr 8:71,909,344...71,917,351
Ensembl chr 8:71,909,349...71,916,299

G

abl interactor 1

increases expression

alpha-Chlorohydrin results in increased expression of ABI1 protein

NCBI chr 2:22,830,085...22,930,207
Ensembl chr 2:22,830,085...22,930,253

G

actin binding LIM protein family, member 3

increases expression

alpha-Chlorohydrin results in increased expression of ABLIM3 mRNA; alpha-Chlorohydrin results in increased expression of ABLIM3 protein

PMID:28522335 PMID:34915118

NCBI chr18:61,932,463...62,044,956
Ensembl chr18:61,932,463...62,044,895

G

active BCR-related gene

decreases expression

alpha-Chlorohydrin results in decreased expression of ABR mRNA

NCBI chr11:76,307,560...76,468,515
Ensembl chr11:76,307,560...76,514,384

G

acetyl-Coenzyme A acyltransferase 1A

increases expression

alpha-Chlorohydrin results in increased expression of ACAA1A mRNA

NCBI chr 9:119,170,113...119,179,361
Ensembl chr 9:119,168,742...119,179,365

G

acetyl-CoA acyltransferase 2

decreases expression

alpha-Chlorohydrin results in decreased expression of ACAA2 protein

NCBI chr18:74,912,283...74,939,278
Ensembl chr18:74,912,268...74,939,279

G

acetyl-Coenzyme A carboxylase alpha

increases expression

alpha-Chlorohydrin results in increased expression of ACACA protein

NCBI chr11:84,020,461...84,292,477
Ensembl chr11:84,020,498...84,292,477

G

acyl-Coenzyme A dehydrogenase, medium chain

affects expression
increases expression
decreases expression

alpha-Chlorohydrin affects the expression of ACADM protein
alpha-Chlorohydrin results in increased expression of ACADM mRNA
alpha-Chlorohydrin analog results in decreased expression of ACADM protein

PMID:26597043 PMID:28522335

NCBI chr 3:153,627,990...153,650,280
Ensembl chr 3:153,627,994...153,650,269

G

acyl-Coenzyme A dehydrogenase, short chain

decreases expression

alpha-Chlorohydrin analog results in decreased expression of ACADS protein; alpha-Chlorohydrin results in decreased expression of ACADS protein

NCBI chr 5:115,248,358...115,257,405
Ensembl chr 5:115,248,358...115,257,405

G

acetyl-Coenzyme A acetyltransferase 1

increases expression

alpha-Chlorohydrin analog results in increased expression of ACAT1 protein

NCBI chr 9:53,491,822...53,521,650
Ensembl chr 9:53,491,822...53,521,682

G

angiotensin I converting enzyme

decreases expression

alpha-Chlorohydrin results in decreased expression of ACE mRNA

NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790

G

angiotensin converting enzyme 2

decreases expression

alpha-Chlorohydrin results in decreased expression of ACE2 mRNA

NCBI chr X:162,922,338...162,971,414
Ensembl chr X:162,922,328...162,971,416

G

amino carboxymuconate semialdehyde decarboxylase

decreases expression

alpha-Chlorohydrin results in decreased expression of ACMSD protein

NCBI chr 1:127,657,149...127,695,723
Ensembl chr 1:127,657,150...127,695,715

G

aconitase 1

decreases expression
increases expression
affects expression

alpha-Chlorohydrin analog results in decreased expression of ACO1 protein
alpha-Chlorohydrin results in increased expression of ACO1 mRNA
alpha-Chlorohydrin affects the expression of ACO1 protein

PMID:26597043 PMID:28522335

NCBI chr 4:40,143,429...40,199,011
Ensembl chr 4:40,143,081...40,198,338

G

acyl-CoA thioesterase 12

decreases expression

alpha-Chlorohydrin results in decreased expression of ACOT12 protein

NCBI chr13:91,889,635...91,934,271
Ensembl chr13:91,889,631...91,934,267

G

acyl-CoA thioesterase 7

decreases expression

alpha-Chlorohydrin results in decreased expression of ACOT7 mRNA

NCBI chr 4:152,258,872...152,356,312
Ensembl chr 4:152,262,591...152,356,312

G

acyl-CoA thioesterase 9

decreases expression

alpha-Chlorohydrin results in decreased expression of ACOT9 mRNA

NCBI chr X:154,045,439...154,080,650
Ensembl chr X:154,045,439...154,080,650

G

acyl-Coenzyme A oxidase 1, palmitoyl

decreases expression

alpha-Chlorohydrin results in decreased expression of ACOX1 protein

NCBI chr11:116,062,714...116,089,605
Ensembl chr11:116,062,714...116,089,871

G

acid phosphatase 6, lysophosphatidic

increases expression

alpha-Chlorohydrin results in increased expression of ACP6 protein

NCBI chr 3:97,066,070...97,083,892
Ensembl chr 3:97,066,093...97,084,615

G

acyl-CoA synthetase family member 2

decreases expression

alpha-Chlorohydrin results in decreased expression of ACSF2 protein

NCBI chr11:94,447,928...94,492,822
Ensembl chr11:94,447,928...94,492,697

G

acyl-CoA synthetase long-chain family member 1

increases expression
decreases expression

alpha-Chlorohydrin results in increased expression of ACSL1 protein
alpha-Chlorohydrin analog results in decreased expression of ACSL1 protein

NCBI chr 8:46,924,214...46,989,088
Ensembl chr 8:46,924,074...46,989,088

G

acyl-CoA synthetase long-chain family member 3

increases expression

alpha-Chlorohydrin results in increased expression of ACSL3 protein

NCBI chr 1:78,635,600...78,685,462
Ensembl chr 1:78,635,542...78,685,460

G

acyl-CoA synthetase long-chain family member 4

increases expression

alpha-Chlorohydrin results in increased expression of ACSL4 protein

NCBI chr X:141,100,989...141,173,792
Ensembl chr X:141,100,989...141,173,531

G

acyl-CoA synthetase long-chain family member 5

decreases expression

alpha-Chlorohydrin results in decreased expression of ACSL5 mRNA

NCBI chr19:55,240,298...55,285,060
Ensembl chr19:55,240,370...55,286,152

G

acyl-CoA synthetase medium-chain family member 3

decreases expression
multiple interactions

alpha-Chlorohydrin results in decreased expression of ACSM3 mRNA
[alpha-Chlorohydrin co-treated with glycidol] results in decreased expression of ACSM3 mRNA

PMID:28522335 PMID:33187795

NCBI chr 7:119,360,106...119,384,119
Ensembl chr 7:119,360,146...119,386,736

G

acyl-CoA synthetase medium-chain family member 5

increases expression

alpha-Chlorohydrin results in increased expression of ACSM5 protein

NCBI chr 7:119,125,354...119,142,583
Ensembl chr 7:119,118,686...119,144,774

G

acyl-CoA synthetase short-chain family member 3

increases expression

alpha-Chlorohydrin results in increased expression of ACSS3 mRNA

NCBI chr10:106,769,375...106,959,622
Ensembl chr10:106,769,378...106,959,529

G

actin, beta

decreases expression
affects expression

alpha-Chlorohydrin analog results in decreased expression of ACTB protein; alpha-Chlorohydrin results in decreased expression of ACTB protein
alpha-Chlorohydrin affects the expression of ACTB protein; alpha-Chlorohydrin analog affects the expression of ACTB protein

PMID:26072098 PMID:26597043

NCBI chr 5:142,888,870...142,892,509
Ensembl chr 5:142,888,870...142,892,509

G

actinin, alpha 1

increases expression

alpha-Chlorohydrin results in increased expression of ACTN1 mRNA; alpha-Chlorohydrin results in increased expression of ACTN1 protein

PMID:26072098 PMID:28522335

NCBI chr12:80,214,316...80,307,165
Ensembl chr12:80,214,321...80,307,145

G

actinin alpha 4

increases expression

alpha-Chlorohydrin results in increased expression of ACTN4 protein

NCBI chr 7:28,592,673...28,661,799
Ensembl chr 7:28,592,673...28,661,765

G

aminoacylase 1

decreases expression

alpha-Chlorohydrin results in decreased expression of ACY1 protein

NCBI chr 9:106,310,180...106,315,594
Ensembl chr 9:106,310,180...106,315,518

G

aminoacylase 3

decreases expression

alpha-Chlorohydrin results in decreased expression of ACY3 protein

NCBI chr19:4,036,570...4,040,007
Ensembl chr19:4,036,570...4,040,007

G

a disintegrin and metallopeptidase domain 1a

decreases expression

alpha-Chlorohydrin results in decreased expression of ADAM1A mRNA

NCBI chr 5:121,656,667...121,659,758
Ensembl chr 5:121,656,639...121,660,134

G

a disintegrin and metallopeptidase domain 23

increases expression

alpha-Chlorohydrin results in increased expression of ADAM23 mRNA

NCBI chr 1:63,484,880...63,635,263
Ensembl chr 1:63,485,050...63,635,435

G

ArfGAP with dual PH domains 2

increases expression

alpha-Chlorohydrin results in increased expression of ADAP2 mRNA

NCBI chr11:80,044,869...80,071,449
Ensembl chr11:80,044,931...80,069,784

G

adenosine deaminase, RNA-specific

increases expression

alpha-Chlorohydrin results in increased expression of ADAR protein

NCBI chr 3:89,622,321...89,660,756
Ensembl chr 3:89,622,329...89,660,753

G

alcohol dehydrogenase 1 (class I)

decreases expression

alpha-Chlorohydrin results in decreased expression of ADH1 protein

NCBI chr 3:137,983,346...137,996,459
Ensembl chr 3:137,966,752...137,996,459

G

adhesion regulating molecule 1 26S proteasome ubiquitin receptor

decreases expression

alpha-Chlorohydrin results in decreased expression of ADRM1 protein

NCBI chr 2:179,813,381...179,818,076
Ensembl chr 2:179,813,278...179,818,079

G

actin filament associated protein 1

affects expression

alpha-Chlorohydrin affects the expression of AFAP1 mRNA

NCBI chr 5:36,050,713...36,161,267
Ensembl chr 5:36,050,663...36,161,267

G

AFG2 AAA ATPase homolog A

increases expression

alpha-Chlorohydrin results in increased expression of AFG2A protein

NCBI chr 3:37,474,052...37,633,245
Ensembl chr 3:37,474,045...37,633,245

G

AFG3-like AAA ATPase 2

increases expression

alpha-Chlorohydrin results in increased expression of AFG3L2 protein

NCBI chr18:67,537,830...67,582,277
Ensembl chr18:67,537,834...67,582,242

G

arylformamidase

decreases expression

alpha-Chlorohydrin results in decreased expression of AFMID mRNA

NCBI chr11:117,716,329...117,730,734
Ensembl chr11:117,716,750...117,730,734

G

aftiphilin

increases expression

alpha-Chlorohydrin results in increased expression of AFTPH protein

NCBI chr11:20,635,084...20,691,599
Ensembl chr11:20,635,084...20,691,589

G

ArfGAP with FG repeats 2

increases expression

alpha-Chlorohydrin results in increased expression of CCZ1B protein

NCBI chr 5:137,648,725...137,683,068
Ensembl chr 5:137,648,725...137,682,988

G

1-acylglycerol-3-phosphate O-acyltransferase 1

decreases expression

alpha-Chlorohydrin results in decreased expression of AGPAT1 protein

NCBI chr17:34,823,164...34,832,392
Ensembl chr17:34,823,236...34,832,423

G

agrin

decreases expression

alpha-Chlorohydrin results in decreased expression of AGRN mRNA

NCBI chr 4:156,249,747...156,281,997
Ensembl chr 4:156,249,747...156,281,945

G

AHNAK nucleoprotein

affects expression

alpha-Chlorohydrin affects the expression of AHNAK mRNA

NCBI chr19:8,966,640...9,054,299
Ensembl chr19:8,966,648...9,054,278

G

apoptosis-inducing factor, mitochondrion-associated 1

decreases expression
increases expression

alpha-Chlorohydrin results in decreased expression of AIFM1 mRNA
alpha-Chlorohydrin results in increased expression of AIFM1 protein

PMID:28070108 PMID:34461274

NCBI chr X:47,563,821...47,602,440
Ensembl chr X:47,563,821...47,602,440

G

aminoacyl tRNA synthetase complex-interacting multifunctional protein 1

increases expression

alpha-Chlorohydrin results in increased expression of AIMP1 protein

NCBI chr 3:132,366,259...132,390,151
Ensembl chr 3:132,366,242...132,390,131

G

aminoacyl tRNA synthetase complex-interacting multifunctional protein 2

increases expression

alpha-Chlorohydrin results in increased expression of AIMP2 protein

NCBI chr 5:143,839,522...143,846,657
Ensembl chr 5:143,839,522...143,846,665

G

aryl-hydrocarbon receptor-interacting protein

decreases expression

alpha-Chlorohydrin analog results in decreased expression of AIP protein

NCBI chr19:4,163,756...4,177,233
Ensembl chr19:4,164,446...4,175,858

G

adenylate kinase 1

increases expression

alpha-Chlorohydrin results in increased expression of AK1 protein

NCBI chr 2:32,511,770...32,525,070
Ensembl chr 2:32,511,770...32,525,070

G

A kinase anchor protein 1

decreases expression

alpha-Chlorohydrin results in decreased expression of AKAP1 mRNA

NCBI chr11:88,721,618...88,755,426
Ensembl chr11:88,721,618...88,755,412

G

A kinase anchor protein 10

increases expression

alpha-Chlorohydrin results in increased expression of AKAP10 protein

NCBI chr11:61,756,029...61,821,134
Ensembl chr11:61,762,133...61,821,078

G

A kinase anchor protein 17B

increases expression

alpha-Chlorohydrin results in increased expression of AKAP17A protein

NCBI chr X:35,871,832...35,909,021
Ensembl chr X:35,871,967...35,909,048

G

A kinase anchor protein 9

increases expression

alpha-Chlorohydrin results in increased expression of AKAP9 protein

NCBI chr 5:3,977,410...4,130,204
Ensembl chr 5:3,978,054...4,131,310

G

aldo-keto reductase family 1, member A1

decreases expression

alpha-Chlorohydrin analog results in decreased expression of AKR1A1 protein; alpha-Chlorohydrin results in decreased expression of AKR1A1 protein

NCBI chr 4:116,493,707...116,508,871
Ensembl chr 4:116,493,707...116,508,877

G

aldo-keto reductase family 1 member B

decreases expression
increases expression

alpha-Chlorohydrin results in decreased expression of AKR1B1 mRNA
alpha-Chlorohydrin results in increased expression of AKR1B1 protein

PMID:28522335 PMID:34915118

NCBI chr 6:34,280,865...34,294,424
Ensembl chr 6:34,279,369...34,294,413

G

aldo-keto reductase family 1, member B10

increases expression

alpha-Chlorohydrin results in increased expression of AKR1B10 mRNA

NCBI chr 6:34,361,182...34,373,884
Ensembl chr 6:34,361,153...34,373,885

G

aldo-keto reductase family 1, member B7

increases expression

alpha-Chlorohydrin results in increased expression of AKR1B7 protein

NCBI chr 6:34,389,297...34,400,072
Ensembl chr 6:34,389,269...34,400,077

G

aldo-keto reductase family 1, member C18

decreases expression

alpha-Chlorohydrin results in decreased expression of AKR1C3 protein

NCBI chr13:4,182,614...4,200,645
Ensembl chr13:4,182,614...4,200,653

G

aldo-keto reductase family 1, member D1

affects expression

alpha-Chlorohydrin analog affects the expression of AKR1D1 protein

NCBI chr 6:37,506,913...37,551,856
Ensembl chr 6:37,507,108...37,545,750

G

aldo-keto reductase family 7, member A5

decreases expression

alpha-Chlorohydrin results in decreased expression of AKR7A2 protein

NCBI chr 4:139,038,005...139,046,097
Ensembl chr 4:139,038,055...139,045,737

G

thymoma viral proto-oncogene 1

increases expression

alpha-Chlorohydrin results in increased expression of AKT1 protein

NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318

G

aminolevulinate, delta-, dehydratase

decreases expression

alpha-Chlorohydrin analog results in decreased expression of ALAD protein; alpha-Chlorohydrin results in decreased expression of ALAD protein

NCBI chr 4:62,422,762...62,438,300
Ensembl chr 4:62,427,406...62,438,155

G

albumin

increases expression

alpha-Chlorohydrin analog results in increased expression of ALB protein; alpha-Chlorohydrin results in increased expression of ALB protein

NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461

G

aldehyde dehydrogenase 16 family, member A1

decreases expression

alpha-Chlorohydrin analog results in decreased expression of ALDH16A1 protein

NCBI chr 7:44,791,257...44,804,008
Ensembl chr 7:44,790,108...44,804,008

G

aldehyde dehydrogenase family 1, subfamily A1

increases expression
decreases expression

alpha-Chlorohydrin results in increased expression of ALDH1A1 mRNA; alpha-Chlorohydrin results in increased expression of ALDH1A1 protein
alpha-Chlorohydrin results in decreased expression of ALDH1A1 mRNA

PMID:26072098 PMID:28522335 PMID:35063618

NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829

G

aldehyde dehydrogenase family 3, subfamily A2

increases expression

alpha-Chlorohydrin analog results in increased expression of ALDH3A2 protein; alpha-Chlorohydrin results in increased expression of ALDH3A2 protein

NCBI chr11:61,114,240...61,158,267
Ensembl chr11:61,114,243...61,158,290

G

aldehyde dehydrogenase 4 family, member A1

decreases expression

alpha-Chlorohydrin results in decreased expression of ALDH4A1 mRNA

NCBI chr 4:139,348,404...139,377,002
Ensembl chr 4:139,350,177...139,377,001

G

aldehyde dehydrogenase family 6, subfamily A1

affects expression

alpha-Chlorohydrin affects the expression of ALDH6A1 protein; alpha-Chlorohydrin analog affects the expression of ALDH6A1 protein

NCBI chr12:84,477,491...84,497,798
Ensembl chr12:84,477,491...84,497,778

G

aldehyde dehydrogenase family 7, member A1

increases expression

alpha-Chlorohydrin results in increased expression of ALDH7A1 mRNA

NCBI chr18:56,657,794...56,706,112
Ensembl chr18:56,642,759...56,706,023

G

aldehyde dehydrogenase 9, subfamily A1

affects expression
decreases expression

alpha-Chlorohydrin analog affects the expression of ALDH9A1 protein
alpha-Chlorohydrin results in decreased expression of ALDH9A1 protein

PMID:26072098 PMID:26597043

NCBI chr 1:167,177,560...167,196,100
Ensembl chr 1:167,177,560...167,196,101

G

alsin Rho guanine nucleotide exchange factor

increases expression

alpha-Chlorohydrin results in increased expression of ALS2 protein

NCBI chr 1:59,201,915...59,276,390
Ensembl chr 1:59,202,085...59,276,390

G

alpha-methylacyl-CoA racemase

decreases expression
affects expression

alpha-Chlorohydrin results in decreased expression of AMACR protein
alpha-Chlorohydrin analog affects the expression of AMACR protein

NCBI chr15:10,981,875...10,995,693
Ensembl chr15:10,981,842...10,996,712

G

amidohydrolase domain containing 2

increases expression

alpha-Chlorohydrin results in increased expression of AMDHD2 protein

NCBI chr17:24,374,807...24,382,752
Ensembl chr17:24,374,807...24,382,740

G

adenosine monophosphate deaminase 3

decreases expression
increases expression

alpha-Chlorohydrin results in decreased expression of AMPD3 mRNA
alpha-Chlorohydrin results in increased expression of AMPD3 protein

PMID:28522335 PMID:34915118

NCBI chr 7:110,367,291...110,411,612
Ensembl chr 7:110,367,413...110,411,612

G

aminomethyltransferase

increases expression

alpha-Chlorohydrin results in increased expression of AMT mRNA

NCBI chr 9:108,174,104...108,179,501
Ensembl chr 9:108,174,052...108,179,501

G

angiopoietin 1

increases expression

alpha-Chlorohydrin results in increased expression of ANGPT1 mRNA

NCBI chr15:42,288,063...42,540,373
Ensembl chr15:42,288,119...42,540,373

G

angiopoietin-like 7

increases expression

alpha-Chlorohydrin results in increased expression of ANGPTL7 mRNA

NCBI chr 4:148,579,737...148,584,919
Ensembl chr 4:148,579,640...148,584,917

G

ankyrin repeat and MYND domain containing 2

increases expression

alpha-Chlorohydrin results in increased expression of ANKMY2 protein

NCBI chr12:36,207,123...36,247,290
Ensembl chr12:36,207,113...36,247,290

G

ankyrin repeat domain 17

increases expression

alpha-Chlorohydrin results in increased expression of ANKRD17 protein

NCBI chr 5:90,375,025...90,517,133
Ensembl chr 5:90,375,025...90,514,436

G

ankyrin repeat domain 33B

increases expression

alpha-Chlorohydrin results in increased expression of ANKRD33B mRNA

NCBI chr15:31,278,328...31,370,446
Ensembl chr15:31,291,624...31,367,872

G

ankyrin repeat and zinc finger domain containing 1

increases expression

alpha-Chlorohydrin results in increased expression of ANKZF1 protein

NCBI chr 1:75,168,794...75,176,031
Ensembl chr 1:75,168,795...75,176,031

G

anoctamin 1, calcium activated chloride channel

increases expression

alpha-Chlorohydrin results in increased expression of ANO1 mRNA

NCBI chr 7:144,142,286...144,305,762
Ensembl chr 7:144,142,286...144,305,711

G

acidic nuclear phosphoprotein 32 family member E

increases expression

alpha-Chlorohydrin results in increased expression of ANP32E protein

NCBI chr 3:95,836,557...95,854,699
Ensembl chr 3:95,836,558...95,854,702

G

annexin A1

increases expression

alpha-Chlorohydrin results in increased expression of ANXA1 protein

NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308

G

annexin A2

increases expression
decreases expression

alpha-Chlorohydrin results in increased expression of ANXA2 protein
alpha-Chlorohydrin results in decreased expression of ANXA2 mRNA

PMID:26072098 PMID:28522335 PMID:34915118

NCBI chr 9:69,360,978...69,399,074
Ensembl chr 9:69,360,902...69,399,077

G

annexin A4

increases expression

alpha-Chlorohydrin results in increased expression of ANXA4 protein

NCBI chr 6:86,713,822...86,770,616
Ensembl chr 6:86,713,822...86,770,566

G

annexin A7

increases expression

alpha-Chlorohydrin results in increased expression of ANXA7 protein

NCBI chr14:20,505,344...20,530,009
Ensembl chr14:20,505,328...20,530,201

G

aldehyde oxidase 1

increases expression

alpha-Chlorohydrin results in increased expression of AOX1 protein

NCBI chr 1:58,068,963...58,145,569
Ensembl chr 1:58,069,090...58,145,572

G

adaptor protein complex AP-1, gamma 2 subunit

increases expression

alpha-Chlorohydrin results in increased expression of AP1G2 protein

NCBI chr14:55,336,292...55,344,050
Ensembl chr14:55,336,032...55,344,050

G

adaptor-related protein complex 3, beta 2 subunit

decreases expression

alpha-Chlorohydrin results in decreased expression of AP3B2 mRNA

NCBI chr 7:81,110,147...81,143,722
Ensembl chr 7:81,110,147...81,143,673

G

adaptor-related protein complex AP-4, epsilon 1

increases expression

alpha-Chlorohydrin results in increased expression of AP4E1 protein

NCBI chr 2:126,850,600...126,911,734
Ensembl chr 2:126,850,637...126,909,829

G

adaptor-related protein complex 5, beta 1 subunit

increases expression

alpha-Chlorohydrin results in increased expression of AP5B1 protein

NCBI chr19:5,610,278...5,621,290
Ensembl chr19:5,618,053...5,621,289

G

adaptor-related protein 5 complex, sigma 1 subunit

increases expression

alpha-Chlorohydrin results in increased expression of AP5S1 protein

NCBI chr 2:131,052,280...131,055,434
Ensembl chr 2:131,048,998...131,055,434

G

apoptotic peptidase activating factor 1

increases expression
multiple interactions

alpha-Chlorohydrin results in increased expression of APAF1 mRNA; alpha-Chlorohydrin results in increased expression of APAF1 protein
3-methyladenine inhibits the reaction [Diosgenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of APAF1 protein]]; Diosgenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of APAF1 protein]
4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of APAF1 protein]; Apigenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of APAF1 mRNA]

PMID:30107153 PMID:33651226 PMID:35149085

NCBI chr10:90,825,173...90,918,688
Ensembl chr10:90,825,173...90,918,632

G

amyloid beta precursor protein binding family B member 1 interacting protein

decreases expression

alpha-Chlorohydrin results in decreased expression of APBB1IP mRNA

NCBI chr 2:22,645,983...22,765,671
Ensembl chr 2:22,664,106...22,765,665

G

amyloid P component, serum

increases expression

alpha-Chlorohydrin results in increased expression of APCS mRNA

NCBI chr 1:172,721,528...172,722,516
Ensembl chr 1:172,721,528...172,722,608

G

acylpeptide hydrolase

decreases expression

alpha-Chlorohydrin analog results in decreased expression of APEH protein; alpha-Chlorohydrin results in decreased expression of APEH protein

NCBI chr 9:107,962,613...107,971,736
Ensembl chr 9:107,962,612...107,971,805

G

apolipoprotein A-II

increases expression

alpha-Chlorohydrin results in increased expression of APOA2 protein

NCBI chr 1:171,049,133...171,053,948
Ensembl chr 1:171,052,623...171,053,948

G

apolipoprotein B

increases expression

alpha-Chlorohydrin results in increased expression of APOB mRNA

NCBI chr12:8,027,629...8,066,839
Ensembl chr12:8,027,648...8,066,835

G

apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3

increases expression

alpha-Chlorohydrin results in increased expression of APOBEC3B mRNA

NCBI chr15:79,774,620...79,802,419
Ensembl chr15:79,775,860...79,800,107

G

apolipoprotein E

increases expression

alpha-Chlorohydrin analog results in increased expression of APOE protein; alpha-Chlorohydrin results in increased expression of APOE protein

PMID:26597043 PMID:34915118

NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113

G

amyloid beta precursor protein

decreases expression

alpha-Chlorohydrin results in decreased expression of APP mRNA

NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654

G

aquaporin 6

decreases expression

alpha-Chlorohydrin results in decreased expression of AQP6 mRNA

NCBI chr15:99,495,891...99,503,359
Ensembl chr15:99,499,281...99,503,358

G

aquaporin 7

increases expression

alpha-Chlorohydrin results in increased expression of AQP7 protein

NCBI chr 4:41,033,074...41,048,237
Ensembl chr 4:41,033,074...41,048,139

G

androgen receptor

decreases expression

alpha-Chlorohydrin results in decreased expression of AR protein

NCBI chr X:97,192,363...97,366,824
Ensembl chr X:97,192,375...97,366,821

G

ARF GTPase activating protein 1

increases expression

alpha-Chlorohydrin results in increased expression of ARFGAP1 protein

NCBI chr 2:180,608,290...180,624,319
Ensembl chr 2:180,609,018...180,624,319

G

arginase, liver

decreases expression
increases expression

alpha-Chlorohydrin analog results in decreased expression of ARG1 protein
alpha-Chlorohydrin results in increased expression of ARG1 protein

PMID:26597043 PMID:34915118

NCBI chr10:24,791,105...24,803,368
Ensembl chr10:24,791,119...24,803,382

G

Rho, GDP dissociation inhibitor beta

increases expression

alpha-Chlorohydrin results in increased expression of ARHGDIB protein

NCBI chr 6:136,900,653...136,918,895
Ensembl chr 6:136,900,653...136,918,897

G

Rho guanine nucleotide exchange factor 5

increases expression

alpha-Chlorohydrin results in increased expression of ARHGEF5 protein

NCBI chr 6:43,242,578...43,266,250
Ensembl chr 6:43,242,516...43,266,254

G

armadillo repeat containing 6

increases expression

alpha-Chlorohydrin results in increased expression of ARMC6 protein

NCBI chr 8:70,672,822...70,687,099
Ensembl chr 8:70,672,822...70,687,116

G

armadillo repeat containing 9

increases expression

alpha-Chlorohydrin results in increased expression of ARMC9 protein

NCBI chr 1:86,082,436...86,207,491
Ensembl chr 1:86,082,502...86,206,006

G

actin related protein 2/3 complex, subunit 1B

increases expression

alpha-Chlorohydrin results in increased expression of ARPC1B protein

NCBI chr 5:145,051,066...145,064,996
Ensembl chr 5:145,051,025...145,067,515

G

actin related protein 2/3 complex, subunit 4

increases expression

alpha-Chlorohydrin results in increased expression of ARPC4 mRNA

NCBI chr 6:113,355,074...113,367,408
Ensembl chr 6:113,355,076...113,367,409

G

arrestin domain containing 2

decreases expression

alpha-Chlorohydrin results in decreased expression of ARRDC2 mRNA

NCBI chr 8:71,287,773...71,293,173
Ensembl chr 8:71,287,773...71,292,364

G

arylsulfatase A

increases expression

alpha-Chlorohydrin results in increased expression of ARSA protein

NCBI chr15:89,356,679...89,361,627
Ensembl chr15:89,356,679...89,361,628

G

arsenite methyltransferase

increases expression

alpha-Chlorohydrin analog results in increased expression of AS3MT protein

NCBI chr19:46,695,124...46,729,538
Ensembl chr19:46,695,897...46,729,538

G

activating signal cointegrator 1 complex subunit 1

increases expression

alpha-Chlorohydrin results in increased expression of ASCC1 protein

NCBI chr10:59,838,414...59,935,812
Ensembl chr10:59,838,627...59,935,810

G

argininosuccinate lyase

increases expression

alpha-Chlorohydrin results in increased expression of ASL mRNA; alpha-Chlorohydrin results in increased expression of ASL protein

PMID:26597043 PMID:28522335

NCBI chr 5:130,040,099...130,053,222
Ensembl chr 5:130,040,099...130,058,088

G

asparagine synthetase

increases expression

alpha-Chlorohydrin results in increased expression of ASNS protein

NCBI chr 6:7,675,169...7,693,209
Ensembl chr 6:7,675,169...7,693,254

G

aspartate dehydrogenase domain containing

decreases expression

alpha-Chlorohydrin results in decreased expression of ASPDH protein

NCBI chr 7:44,114,859...44,117,175
Ensembl chr 7:44,114,815...44,117,182

G

ASPSCR1 tether for SLC2A4, UBX domain containing

increases expression

alpha-Chlorohydrin results in increased expression of ASPSCR1 protein

NCBI chr11:120,563,878...120,600,273
Ensembl chr11:120,563,799...120,600,273

G

argininosuccinate synthetase 1

increases expression

alpha-Chlorohydrin results in increased expression of ASS1 mRNA

NCBI chr 2:31,360,282...31,410,682
Ensembl chr 2:31,360,219...31,410,684

G

ATPase family, AAA domain containing 1

increases expression

alpha-Chlorohydrin results in increased expression of ATAD1 protein

NCBI chr19:32,649,958...32,717,187
Ensembl chr19:32,649,038...32,717,186

G

ATPase family, AAA domain containing 3A

increases expression

alpha-Chlorohydrin results in increased expression of ATAD3A protein

NCBI chr 4:155,825,097...155,845,579
Ensembl chr 4:155,825,098...155,845,550

G

activating transcription factor 4

multiple interactions
increases expression

4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of ATF4 protein]

NCBI chr15:80,139,385...80,141,746
Ensembl chr15:80,139,385...80,141,742

G

activating transcription factor 6

multiple interactions

[4-phenylbutyric acid co-treated with alpha-Chlorohydrin] results in decreased expression of ATF6 protein
alpha-Chlorohydrin results in increased expression of and affects the cleavage of ATF6 protein

NCBI chr 1:170,532,026...170,696,414
Ensembl chr 1:170,532,243...170,695,340

G

autophagy related 12

increases expression

alpha-Chlorohydrin results in increased expression of ATG12 protein

NCBI chr18:46,865,484...46,874,683
Ensembl chr18:46,863,211...46,874,647

G

autophagy related 13

increases expression

alpha-Chlorohydrin results in increased expression of ATG13 protein

NCBI chr 2:91,504,957...91,540,947
Ensembl chr 2:91,504,963...91,540,921

G

autophagy related 16 like 1

increases expression

alpha-Chlorohydrin results in increased expression of ATG16L1 protein

NCBI chr 1:87,683,730...87,720,150
Ensembl chr 1:87,683,592...87,720,150

G

autophagy related 5

increases expression

alpha-Chlorohydrin results in increased expression of ATG5 protein

NCBI chr10:44,144,325...44,240,295
Ensembl chr10:44,144,354...44,240,287

G

ATPase type 13A1

increases expression

alpha-Chlorohydrin results in increased expression of ATP13A1 protein

NCBI chr 8:70,243,813...70,260,399
Ensembl chr 8:70,243,813...70,260,399

G

ATPase, Na+/K+ transporting, beta 1 polypeptide

decreases expression

alpha-Chlorohydrin results in decreased expression of ATP1B1 mRNA

NCBI chr 1:164,264,668...164,285,924
Ensembl chr 1:164,264,678...164,285,924

G

ATP synthase F1 subunit alpha

increases expression

alpha-Chlorohydrin analog results in increased expression of ATP5F1A protein

NCBI chr18:77,861,468...77,870,569
Ensembl chr18:77,861,429...77,870,569

G

ATP synthase membrane subunit k

decreases expression

alpha-Chlorohydrin results in decreased expression of ATP5MK mRNA

NCBI chr19:47,071,910...47,079,086
Ensembl chr19:47,071,903...47,079,086

G

ATPase, H+ transporting, lysosomal accessory protein 2

increases expression

alpha-Chlorohydrin results in increased expression of ATP6AP2 mRNA

NCBI chr X:12,453,998...12,483,290
Ensembl chr X:12,454,040...12,483,288

G

ATPase, H+ transporting, lysosomal V1 subunit A

decreases expression
multiple interactions

alpha-Chlorohydrin results in decreased expression of ATP6V1A mRNA
ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in decreased expression of ATP6V1A mRNA]

PMID:32702505 PMID:34812491

NCBI chr16:43,905,765...43,960,055
Ensembl chr16:43,905,765...43,960,068

G

ATPase, H+ transporting, lysosomal V1 subunit B2

decreases expression
multiple interactions
increases expression

alpha-Chlorohydrin results in decreased expression of ATP6V1B2 mRNA; alpha-Chlorohydrin results in decreased expression of ATP6V1B2 protein
ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in decreased expression of ATP6V1B2 mRNA]
alpha-Chlorohydrin results in increased expression of ATP6V1B2 mRNA

PMID:27732882 PMID:28522335 PMID:32702505 PMID:34812491

NCBI chr 8:69,541,388...69,566,370
Ensembl chr 8:69,541,298...69,566,363

G

ATPase, H+ transporting, lysosomal V1 subunit G3

decreases expression

alpha-Chlorohydrin results in decreased expression of ATP6V1G3 mRNA

NCBI chr 1:138,201,476...138,217,200
Ensembl chr 1:138,201,476...138,217,200

G

ATPase phospholipid transporting 8A1

increases expression

alpha-Chlorohydrin results in increased expression of ATP8A1 mRNA

NCBI chr 5:67,775,482...68,004,822
Ensembl chr 5:67,775,483...68,004,777

G

ATPase, class I, type 8B, member 2

decreases expression

alpha-Chlorohydrin results in decreased expression of ATP8B2 protein

NCBI chr 3:89,846,795...89,870,645
Ensembl chr 3:89,846,788...89,870,815

G

all-trans retinoic acid induced differentiation factor

decreases expression

alpha-Chlorohydrin results in decreased expression of ATRAID mRNA

NCBI chr 5:31,205,984...31,211,977
Ensembl chr 5:31,205,656...31,211,967

G

expressed sequence AU022252

increases expression

alpha-Chlorohydrin results in increased expression of C5H1ORF50 protein

NCBI chr 4:119,077,039...119,089,884
Ensembl chr 4:119,060,767...119,089,909

G

ancient ubiquitous protein 1

increases expression

alpha-Chlorohydrin results in increased expression of AUP1 protein

NCBI chr 6:83,031,483...83,034,663
Ensembl chr 6:83,031,502...83,034,789

G

arginine vasopressin receptor 1A

increases expression

alpha-Chlorohydrin results in increased expression of AVPR1A mRNA

NCBI chr10:122,284,404...122,289,358
Ensembl chr10:122,284,404...122,289,357

G

beta-1,3-glucuronyltransferase 1

increases expression

alpha-Chlorohydrin results in increased expression of B3GAT1 mRNA

NCBI chr 9:26,644,813...26,672,646
Ensembl chr 9:26,645,024...26,674,397

G

UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5

increases expression

alpha-Chlorohydrin results in increased expression of B4GALT5 mRNA

NCBI chr 2:167,140,364...167,191,155
Ensembl chr 2:167,140,364...167,191,103

G

bile acid-Coenzyme A: amino acid N-acyltransferase

increases expression

alpha-Chlorohydrin analog results in increased expression of BAAT protein
alpha-Chlorohydrin results in increased expression of BAAT mRNA

PMID:26597043 PMID:33187795

NCBI chr 4:49,489,416...49,507,915
Ensembl chr 4:49,489,422...49,506,557

G

BCL2-associated athanogene 2

increases expression

alpha-Chlorohydrin results in increased expression of BAG2 protein

NCBI chr 1:33,784,565...33,796,831
Ensembl chr 1:33,784,565...33,796,876

G

BAI1-associated protein 2-like 1

increases expression

alpha-Chlorohydrin results in increased expression of BAIAP2L1 mRNA

NCBI chr 5:144,201,335...144,294,922
Ensembl chr 5:144,201,336...144,294,922

G

BAF nuclear assembly factor 1

increases expression

alpha-Chlorohydrin results in increased expression of BANF1 protein

NCBI chr19:5,414,661...5,416,904
Ensembl chr19:5,414,666...5,417,196

G

BTG3 associated nuclear protein

increases expression

alpha-Chlorohydrin results in increased expression of BANP mRNA

NCBI chr 8:122,674,711...122,755,999
Ensembl chr 8:122,676,489...122,755,997

G

BCL2-associated X protein

increases expression
multiple interactions

alpha-Chlorohydrin results in increased expression of BAX mRNA; alpha-Chlorohydrin results in increased expression of BAX protein
4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of BAX protein]; Apigenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of BAX mRNA]; Apigenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of BAX protein]

PMID:27732882 PMID:28070108 PMID:30107153 PMID:33651226 PMID:34915118

NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322

G

breast cancer anti-estrogen resistance 1

increases expression

alpha-Chlorohydrin results in increased expression of BCAR1 protein

NCBI chr 8:112,437,106...112,470,481
Ensembl chr 8:112,437,106...112,470,441

G

BCAS3 microtubule associated cell migration factor

increases expression

alpha-Chlorohydrin results in increased expression of BCAS3 protein

NCBI chr11:85,243,611...85,716,884
Ensembl chr11:85,243,993...85,716,884

G

branched chain ketoacid dehydrogenase E1, alpha polypeptide

decreases expression

alpha-Chlorohydrin analog results in decreased expression of BCKDHA protein; alpha-Chlorohydrin results in decreased expression of BCKDHA protein

NCBI chr 7:25,329,371...25,358,178
Ensembl chr 7:25,329,371...25,358,406

G

B cell leukemia/lymphoma 2

decreases expression
multiple interactions

alpha-Chlorohydrin results in decreased expression of BCL2 mRNA; alpha-Chlorohydrin results in decreased expression of BCL2 protein
4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in decreased expression of BCL2 protein]; Apigenin inhibits the reaction [alpha-Chlorohydrin results in decreased expression of BCL2 mRNA]

PMID:27732882 PMID:28070108 PMID:30107153 PMID:33651226 PMID:34915118

NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004

G

BCL2 like 14

increases expression

alpha-Chlorohydrin results in increased expression of BCL2L14 protein

NCBI chr 6:134,373,292...134,415,687
Ensembl chr 6:134,373,281...134,415,699

G

betaine-homocysteine methyltransferase

decreases expression

alpha-Chlorohydrin analog results in decreased expression of BHMT protein; alpha-Chlorohydrin results in decreased expression of BHMT protein

PMID:26597043 PMID:34915118

NCBI chr13:93,753,399...93,774,266
Ensembl chr13:93,753,183...93,774,469

G

BicC family RNA binding protein 1

increases expression

alpha-Chlorohydrin results in increased expression of BICC1 protein

NCBI chr10:70,758,660...70,995,581
Ensembl chr10:70,758,662...70,995,530

G

BH3 interacting domain death agonist

increases expression

alpha-Chlorohydrin results in increased expression of BID mRNA

NCBI chr 6:120,870,080...120,894,074
Ensembl chr 6:120,868,891...120,893,814

G

BCL2-interacting killer

increases expression

alpha-Chlorohydrin results in increased expression of BIK mRNA

NCBI chr15:83,410,992...83,428,836
Ensembl chr15:83,411,063...83,428,835

G

baculoviral IAP repeat-containing 3

decreases expression

alpha-Chlorohydrin results in decreased expression of BIRC3 mRNA

NCBI chr 9:7,848,698...7,873,199
Ensembl chr 9:7,848,700...7,873,187

G

bridge-like lipid transfer protein family member 3B

increases expression

alpha-Chlorohydrin results in increased expression of BLTP3B protein

NCBI chr10:89,580,830...89,655,753
Ensembl chr10:89,580,853...89,655,733

G

basic helix-loop-helix ARNT like 1

decreases expression

alpha-Chlorohydrin results in decreased expression of BMAL1 mRNA

NCBI chr 7:112,777,820...112,913,333
Ensembl chr 7:112,806,672...112,913,333

G

bone morphogenetic protein 3

decreases expression

alpha-Chlorohydrin results in decreased expression of BMP3 mRNA

NCBI chr 5:99,002,274...99,031,912
Ensembl chr 5:99,002,274...99,032,255

G

block of proliferation 1

increases expression

alpha-Chlorohydrin results in increased expression of BOP1 protein

NCBI chr15:76,337,188...76,361,449
Ensembl chr15:76,337,189...76,361,477

G

BLOC-1 related complex subunit 8

increases expression

alpha-Chlorohydrin results in increased expression of BORCS8 mRNA

NCBI chr 8:70,592,149...70,601,285
Ensembl chr 8:70,592,149...70,599,969

G

biphenyl hydrolase like

decreases expression

alpha-Chlorohydrin results in decreased expression of BPHL protein

NCBI chr13:34,221,611...34,258,055
Ensembl chr13:34,221,580...34,258,057

G

basigin

increases expression

alpha-Chlorohydrin results in increased expression of BSG protein

NCBI chr10:79,540,192...79,547,813
Ensembl chr10:79,540,325...79,547,803

G

bone marrow stromal cell antigen 2

increases expression

alpha-Chlorohydrin results in increased expression of BST2 mRNA

NCBI chr 8:71,986,899...71,990,116
Ensembl chr 8:71,986,899...71,990,100

G

BTG anti-proliferation factor 2

decreases expression

alpha-Chlorohydrin results in decreased expression of BTG2 mRNA

NCBI chr 1:134,002,603...134,006,893
Ensembl chr 1:134,002,908...134,006,858

G

C2 calcium-dependent domain containing 2-like

increases expression

alpha-Chlorohydrin results in increased expression of C2CD2L mRNA

NCBI chr 9:44,220,534...44,231,579
Ensembl chr 9:44,220,534...44,231,582

G

calcium channel, voltage-dependent, alpha2/delta subunit 3

increases expression

alpha-Chlorohydrin results in increased expression of CACNA2D3 protein

NCBI chr14:28,626,900...29,444,732
Ensembl chr14:28,626,900...29,443,821

G

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

increases expression

alpha-Chlorohydrin results in increased expression of CAD protein

NCBI chr 5:31,211,964...31,235,823
Ensembl chr 5:31,212,124...31,235,823

G

cell adhesion molecule 1

increases expression

alpha-Chlorohydrin results in increased expression of CADM1 protein

NCBI chr 9:47,441,468...47,773,578
Ensembl chr 9:47,441,471...47,769,413

G

calbindin 2

increases expression

alpha-Chlorohydrin results in increased expression of CALB2 mRNA

NCBI chr 8:110,869,158...110,894,844
Ensembl chr 8:110,864,134...110,894,842

G

calneuron 1

decreases expression

alpha-Chlorohydrin results in decreased expression of CALN1 mRNA

NCBI chr 5:130,398,245...130,876,253
Ensembl chr 5:130,398,296...130,876,253

G

calreticulin

decreases expression

alpha-Chlorohydrin analog results in decreased expression of CALR protein; alpha-Chlorohydrin results in decreased expression of CALR protein

NCBI chr 8:85,568,717...85,573,560
Ensembl chr 8:85,568,479...85,573,563

G

calcium/calmodulin-dependent protein kinase II inhibitor 2

decreases expression

alpha-Chlorohydrin results in decreased expression of CAMK2N2 mRNA

NCBI chr16:20,437,965...20,440,028
Ensembl chr16:20,437,965...20,440,037

G

calcium/calmodulin-dependent protein kinase kinase 2, beta

increases expression
multiple interactions

alpha-Chlorohydrin results in increased expression of CAMKK2 protein
4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of CAMKK2 protein]

NCBI chr 5:122,856,064...122,918,295
Ensembl chr 5:122,869,233...122,917,472

G

cyclase associated actin cytoskeleton regulatory protein 1

increases expression

alpha-Chlorohydrin results in increased expression of CAP1 protein

NCBI chr 4:122,752,841...122,779,869
Ensembl chr 4:122,752,840...122,779,849

G

calpain 1

decreases expression

alpha-Chlorohydrin results in decreased expression of CAPN1 mRNA

NCBI chr19:6,038,573...6,065,855
Ensembl chr19:6,038,573...6,065,927

G

calpain 2

increases expression

alpha-Chlorohydrin results in increased expression of CAPN2 protein

NCBI chr 1:182,294,818...182,345,175
Ensembl chr 1:182,294,825...182,345,173

G

calpain 5

increases expression

alpha-Chlorohydrin results in increased expression of CAPN5 protein

NCBI chr 7:97,770,766...97,828,148
Ensembl chr 7:97,770,766...97,827,481

G

carbonic anhydrase 12

decreases expression

alpha-Chlorohydrin results in decreased expression of CAR12 protein

NCBI chr 9:66,619,026...66,674,127
Ensembl chr 9:66,620,968...66,674,127

G

carbonic anhydrase 3

decreases expression

alpha-Chlorohydrin analog results in decreased expression of CA3 protein; alpha-Chlorohydrin results in decreased expression of CA3 protein

NCBI chr 3:14,928,598...14,937,441
Ensembl chr 3:14,928,572...14,937,583

G

caspase recruitment domain family, member 19

increases expression

alpha-Chlorohydrin results in increased expression of CARD19 protein

NCBI chr13:49,356,426...49,369,471
Ensembl chr13:49,356,426...49,369,513

G

coactivator-associated arginine methyltransferase 1

increases expression

alpha-Chlorohydrin results in increased expression of CARM1 protein

NCBI chr 9:21,458,163...21,500,763
Ensembl chr 9:21,458,190...21,503,919

G

capping protein regulator and myosin 1 linker 1

increases expression

alpha-Chlorohydrin results in increased expression of CARMIL1 protein

NCBI chr13:24,196,464...24,464,983
Ensembl chr13:24,196,327...24,464,778

G

cysteinyl-tRNA synthetase 1

increases expression

alpha-Chlorohydrin results in increased expression of CARS1 protein

NCBI chr 7:143,110,967...143,153,827
Ensembl chr 7:143,110,967...143,153,827

G

caspase 1

decreases expression
multiple interactions
increases cleavage

alpha-Chlorohydrin results in decreased expression of CASP1 mRNA
Cyclosporine inhibits the reaction [ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in increased cleavage of CASP1 protein]]; ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in increased cleavage of CASP1 protein]

PMID:28522335 PMID:33187795 PMID:38373586

NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290

G

caspase 12

multiple interactions

4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of and results in increased cleavage of CASP12 protein]; alpha-Chlorohydrin results in increased expression of and results in increased cleavage of CASP12 protein

NCBI chr 9:5,345,419...5,373,034
Ensembl chr 9:5,345,430...5,373,032

G

caspase 2

multiple interactions
decreases expression

alpha-Chlorohydrin results in increased expression of and results in increased cleavage of and results in increased activity of CASP2 protein; quinoline-val-asp(OMe)-CH2-OPH inhibits the reaction [alpha-Chlorohydrin results in increased activity of CASP2 protein]
alpha-Chlorohydrin results in decreased expression of CASP2 mRNA

NCBI chr 6:42,241,942...42,259,442
Ensembl chr 6:42,241,919...42,259,442

G

caspase 3

decreases expression
multiple interactions
increases cleavage
increases expression
increases activity

alpha-Chlorohydrin results in decreased expression of CASP3 mRNA
4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased cleavage of CASP3 protein]; Apigenin inhibits the reaction [alpha-Chlorohydrin results in increased cleavage of CASP3 protein]; Apigenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of CASP3 mRNA]
alpha-Chlorohydrin results in increased expression of CASP3 mRNA; alpha-Chlorohydrin results in increased expression of CASP3 protein
alpha-Chlorohydrin results in increased activity of CASP3 protein
alpha-Chlorohydrin results in increased expression of and results in increased cleavage of CASP3 protein; Diosgenin inhibits the reaction [alpha-Chlorohydrin results in increased activity of CASP3 protein]

PMID:27732882 PMID:28070108 PMID:30107153 PMID:33651226 PMID:34461274 More...

NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724

G

caspase 6

multiple interactions
decreases expression

alpha-Chlorohydrin results in increased expression of and results in increased activity of CASP6 protein; quinoline-val-asp(OMe)-CH2-OPH inhibits the reaction [alpha-Chlorohydrin results in increased activity of CASP6 protein]
alpha-Chlorohydrin results in decreased expression of CASP6 mRNA

NCBI chr 3:129,695,064...129,707,761
Ensembl chr 3:129,695,074...129,707,752

G

caspase 7

decreases expression
multiple interactions

alpha-Chlorohydrin results in decreased expression of CASP7 mRNA
alpha-Chlorohydrin results in increased expression of and results in increased cleavage of CASP7 protein

NCBI chr19:56,382,640...56,430,780
Ensembl chr19:56,385,561...56,430,776

G

caspase 8

multiple interactions
increases activity
decreases expression

alpha-Chlorohydrin results in increased expression of and results in increased cleavage of and results in increased activity of CASP8 protein; quinoline-val-asp(OMe)-CH2-OPH inhibits the reaction [alpha-Chlorohydrin results in increased activity of CASP8 protein]
alpha-Chlorohydrin results in increased expression of and results in increased cleavage of CASP8 protein
alpha-Chlorohydrin results in decreased expression of CASP8 mRNA

PMID:27732882 PMID:28070108 PMID:34915118

NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662

G

caspase 9

multiple interactions
increases cleavage
increases expression
increases activity
decreases expression

3-methyladenine inhibits the reaction [Diosgenin inhibits the reaction [alpha-Chlorohydrin results in increased activity of CASP9 protein]]; 3-methyladenine inhibits the reaction [Diosgenin inhibits the reaction [alpha-Chlorohydrin results in increased cleavage of CASP9 protein]]; 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased cleavage of CASP9 protein]; alpha-Chlorohydrin results in increased expression of and results in increased cleavage of and results in increased activity of CASP9 protein; alpha-Chlorohydrin results in increased expression of and results in increased cleavage of CASP9 protein; Diosgenin inhibits the reaction [alpha-Chlorohydrin results in increased activity of CASP9 protein]; Diosgenin inhibits the reaction [alpha-Chlorohydrin results in increased cleavage of CASP9 protein]; Diosgenin promotes the reaction [alpha-Chlorohydrin results in increased expression of CASP9 protein]; quinoline-val-asp(OMe)-CH2-OPH inhibits the reaction [alpha-Chlorohydrin results in increased activity of CASP9 protein]
alpha-Chlorohydrin results in increased expression of CASP9 mRNA
4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased cleavage of CASP9 protein]; alpha-Chlorohydrin results in increased expression of and results in increased cleavage of CASP9 protein; Apigenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of and results in increased cleavage of CASP9 protein]; Apigenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of CASP9 mRNA]
alpha-Chlorohydrin results in decreased expression of CASP9 mRNA

PMID:27732882 PMID:28070108 PMID:30107153 PMID:33651226 PMID:35149085

NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287

G

catalase

affects expression
decreases expression

alpha-Chlorohydrin affects the expression of CAT protein; alpha-Chlorohydrin analog affects the expression of CAT protein
alpha-Chlorohydrin results in decreased expression of CAT protein

PMID:26597043 PMID:34915118

NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505

G

carbonyl reductase 3

increases expression

alpha-Chlorohydrin results in increased expression of CBR3 mRNA

NCBI chr16:93,480,107...93,487,879
Ensembl chr16:93,480,103...93,487,878

G

coiled-coil and C2 domain containing 1A

increases expression

alpha-Chlorohydrin results in increased expression of CC2D1A protein

NCBI chr 8:84,859,457...84,874,546
Ensembl chr 8:84,859,457...84,874,565

G

coiled-coil domain containing 115

increases expression

alpha-Chlorohydrin results in increased expression of CCDC115 protein

NCBI chr 1:34,475,751...34,478,753
Ensembl chr 1:34,475,751...34,478,753

G

coiled-coil domain containing 185

decreases expression

alpha-Chlorohydrin results in decreased expression of CCDC185 mRNA

NCBI chr 1:182,574,691...182,576,745
Ensembl chr 1:182,574,691...182,576,745

G

coiled-coil domain containing 6

increases expression

alpha-Chlorohydrin results in increased expression of CCDC6 protein

NCBI chr10:69,932,709...70,029,030
Ensembl chr10:69,932,951...70,029,030

G

coiled-coil domain containing 77

increases expression

alpha-Chlorohydrin results in increased expression of CCDC77 mRNA

NCBI chr 6:120,301,283...120,341,330
Ensembl chr 6:120,301,284...120,341,335

G

coiled-coil domain containing 80

increases expression

alpha-Chlorohydrin results in increased expression of CCDC80 mRNA

NCBI chr16:44,913,770...44,948,287
Ensembl chr16:44,913,765...44,948,440

G

coiled-coil domain containing 85C

increases expression

alpha-Chlorohydrin results in increased expression of CCDC85C mRNA

NCBI chr12:108,169,858...108,244,111
Ensembl chr12:108,169,861...108,241,684

G

coiled-coil domain containing 89

decreases expression

alpha-Chlorohydrin results in decreased expression of CCDC89 mRNA

NCBI chr 7:90,075,520...90,077,872
Ensembl chr 7:90,075,785...90,077,877

G

coiled-coil domain containing 91

increases expression

alpha-Chlorohydrin results in increased expression of CCDC91 protein

NCBI chr 6:147,377,322...147,534,110
Ensembl chr 6:147,377,326...147,534,110

G

coiled-coil glutamate-rich protein 1

decreases expression

alpha-Chlorohydrin results in decreased expression of CCER1 mRNA

NCBI chr10:97,528,921...97,530,788
Ensembl chr10:97,528,921...97,530,785

G

coiled-coil alpha-helical rod protein 1

increases expression

alpha-Chlorohydrin results in increased expression of CCHCR1 protein

NCBI chr17:35,827,914...35,841,912
Ensembl chr17:35,827,997...35,841,912

G

C-C motif chemokine ligand 2

decreases expression
increases expression

alpha-Chlorohydrin results in decreased expression of CCL2 mRNA
alpha-Chlorohydrin results in increased expression of CCL2 protein

PMID:20409345 PMID:26025059

NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279

G

C-C motif chemokine ligand 5

decreases expression

alpha-Chlorohydrin results in decreased expression of CCL5 mRNA

NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344

G

C-C motif chemokine ligand 6

decreases expression

alpha-Chlorohydrin results in decreased expression of CCL6 mRNA

NCBI chr11:83,478,712...83,483,913
Ensembl chr11:83,478,708...83,483,913

G

cyclin A2

increases expression

alpha-Chlorohydrin results in increased expression of CCNA2 mRNA

NCBI chr 3:36,619,014...36,627,187
Ensembl chr 3:36,619,014...36,626,299

G

cyclin B1

increases expression

alpha-Chlorohydrin results in increased expression of CCNB1 mRNA

NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078

G

cyclin E1

decreases expression
increases expression

alpha-Chlorohydrin analog results in decreased expression of CCNE1 protein
alpha-Chlorohydrin results in increased expression of CCNE1 mRNA

PMID:26072098 PMID:38301995

NCBI chr 7:37,797,409...37,806,915
Ensembl chr 7:37,797,409...37,806,959

G

cyclin G1

increases expression

alpha-Chlorohydrin results in increased expression of CCNG1 mRNA

NCBI chr11:40,639,379...40,646,044
Ensembl chr11:40,639,379...40,646,138

G

chaperonin containing TCP1 subunit 2

increases expression

alpha-Chlorohydrin analog results in increased expression of CCT2 protein

NCBI chr10:116,886,902...116,899,757
Ensembl chr10:116,886,906...116,899,719

G

chaperonin containing TCP1 subunit 3

decreases expression

alpha-Chlorohydrin results in decreased expression of CCT3 protein

NCBI chr 3:88,204,442...88,229,073
Ensembl chr 3:88,204,423...88,229,074

G

chaperonin containing TCP1 subunit 4

decreases expression

alpha-Chlorohydrin analog results in decreased expression of CCT4 protein

NCBI chr11:22,940,593...22,953,336
Ensembl chr11:22,940,519...22,953,780

G

chaperonin containing TCP1 subunit 5

increases expression

alpha-Chlorohydrin analog results in increased expression of CCT5 protein

NCBI chr15:31,590,946...31,601,992
Ensembl chr15:31,590,946...31,601,950

G

CD1d1 antigen

increases expression

alpha-Chlorohydrin results in increased expression of CD1D1 protein

NCBI chr 3:86,903,141...86,919,665
Ensembl chr 3:86,903,141...86,906,748

G

CD24a antigen

decreases expression

alpha-Chlorohydrin results in decreased expression of CD24 mRNA

NCBI chr10:43,454,433...43,460,261
Ensembl chr10:43,454,280...43,460,261

G

CD27 antigen

increases expression

alpha-Chlorohydrin results in increased expression of CD27 mRNA

NCBI chr 6:125,209,583...125,214,014
Ensembl chr 6:125,209,585...125,213,973

G

CD2-associated protein

increases expression

alpha-Chlorohydrin results in increased expression of CD2AP protein

NCBI chr17:43,059,857...43,187,593
Ensembl chr17:43,103,842...43,187,556

G

CD2 cytoplasmic tail binding protein 2

increases expression

alpha-Chlorohydrin results in increased expression of CD2BP2 protein

NCBI chr 7:126,790,832...126,795,249
Ensembl chr 7:126,790,832...126,795,222

G

CD302 antigen

increases expression

alpha-Chlorohydrin results in increased expression of CD302 mRNA

NCBI chr 2:60,082,337...60,114,828
Ensembl chr 2:60,082,337...60,114,832

G

CD34 antigen

increases expression

alpha-Chlorohydrin results in increased expression of CD34 mRNA

NCBI chr 1:194,621,239...194,643,587
Ensembl chr 1:194,621,127...194,643,587

G

CD36 molecule

increases expression

alpha-Chlorohydrin results in increased expression of CD36 mRNA

NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799

G

CD38 antigen

decreases expression

alpha-Chlorohydrin results in decreased expression of CD38 mRNA

NCBI chr 5:44,026,153...44,069,714
Ensembl chr 5:44,025,895...44,069,717

G

CD4 antigen

increases expression

alpha-Chlorohydrin results in increased expression of CD4 protein

NCBI chr 6:124,841,656...124,865,210
Ensembl chr 6:124,841,655...124,865,184

G

CD48 antigen

decreases expression

alpha-Chlorohydrin results in decreased expression of CD48 mRNA

NCBI chr 1:171,508,989...171,532,825
Ensembl chr 1:171,509,577...171,532,826

G

CD53 antigen

increases expression

alpha-Chlorohydrin results in increased expression of CD53 mRNA

NCBI chr 3:106,666,177...106,697,465
Ensembl chr 3:106,667,237...106,697,465

G

CD68 antigen

increases expression

alpha-Chlorohydrin results in increased expression of CD68 mRNA

NCBI chr11:69,555,039...69,556,996
Ensembl chr11:69,555,039...69,556,979

G

CD69 antigen

decreases expression

alpha-Chlorohydrin results in decreased expression of CD69 mRNA

NCBI chr 6:129,244,287...129,252,332
Ensembl chr 6:129,244,288...129,252,399

G

CD70 antigen

decreases expression

alpha-Chlorohydrin results in decreased expression of CD70 mRNA

NCBI chr17:57,452,997...57,456,777
Ensembl chr17:57,452,997...57,456,777

G

CD9 antigen

decreases expression
increases expression

alpha-Chlorohydrin results in decreased expression of CD9 mRNA
alpha-Chlorohydrin results in increased expression of CD9 protein

PMID:28522335 PMID:34915118

NCBI chr 6:125,437,229...125,471,723
Ensembl chr 6:125,437,229...125,471,754

G

cell division cycle 123

increases expression

alpha-Chlorohydrin results in increased expression of CDC123 protein

NCBI chr 2:5,799,105...5,849,988
Ensembl chr 2:5,799,105...5,849,975

G

CDC16 cell division cycle 16

increases expression

alpha-Chlorohydrin results in increased expression of CDC16 protein

NCBI chr 8:13,807,650...13,831,951
Ensembl chr 8:13,807,676...13,831,938

G

cell division cycle 25B

decreases expression

alpha-Chlorohydrin results in decreased expression of CDC25B mRNA

NCBI chr 2:131,028,356...131,040,431
Ensembl chr 2:131,028,869...131,040,417

G

cell division cycle 5-like

increases expression

alpha-Chlorohydrin results in increased expression of CDC5L protein

NCBI chr17:45,702,809...45,744,633
Ensembl chr17:45,702,810...45,744,663

G

cell division cycle 6

increases expression

alpha-Chlorohydrin results in increased expression of CDC6 mRNA

NCBI chr11:98,798,627...98,814,768
Ensembl chr11:98,798,627...98,814,766

G

cell division cycle associated 3

decreases expression

alpha-Chlorohydrin analog results in decreased expression of CDCA3 protein; alpha-Chlorohydrin results in decreased expression of CDCA3 mRNA

PMID:26597043 PMID:28522335

NCBI chr 6:124,806,533...124,810,664
Ensembl chr 6:124,806,510...124,810,664

G

cell division cycle associated 8

increases expression

alpha-Chlorohydrin results in increased expression of CDCA8 mRNA

NCBI chr 4:124,812,258...124,830,710
Ensembl chr 4:124,812,258...124,833,104

G

cadherin 1

decreases expression
affects methylation

alpha-Chlorohydrin results in decreased expression of CDH1 mRNA
alpha-Chlorohydrin affects the methylation of CDH1 promoter

PMID:27884059 PMID:28522335

NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878

G

cadherin 2

decreases expression

alpha-Chlorohydrin results in decreased expression of CDH2 mRNA

NCBI chr18:16,721,934...16,942,303
Ensembl chr18:16,721,934...16,942,303

G

cadherin 5

increases expression

alpha-Chlorohydrin results in increased expression of CDH5 mRNA

NCBI chr 8:104,828,247...104,871,136
Ensembl chr 8:104,828,257...104,871,143

G

cadherin-related family member 5

increases expression

alpha-Chlorohydrin results in increased expression of CDHR5 mRNA

NCBI chr 7:140,848,993...140,856,708
Ensembl chr 7:140,848,996...140,856,699

G

CDK5 regulatory subunit associated protein 1

increases expression

alpha-Chlorohydrin results in increased expression of CDK5RAP1 protein

NCBI chr 2:154,063,931...154,216,170
Ensembl chr 2:154,177,300...154,214,930

G

cyclin dependent kinase like 5

increases expression

alpha-Chlorohydrin results in increased expression of CDKL5 mRNA

NCBI chr X:159,567,241...159,777,673
Ensembl chr X:159,554,919...159,777,700

G

cyclin dependent kinase inhibitor 2A

increases expression

alpha-Chlorohydrin analog results in increased expression of CDKN2A protein; alpha-Chlorohydrin results in increased expression of CDKN2A protein

NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890

G

cysteine dioxygenase 1, cytosolic

decreases expression

alpha-Chlorohydrin analog results in decreased expression of CDO1 protein; alpha-Chlorohydrin results in decreased expression of CDO1 protein

NCBI chr18:46,846,260...46,861,569
Ensembl chr18:46,846,260...46,861,462

G

CEA cell adhesion molecule 1

increases expression

alpha-Chlorohydrin results in increased expression of CEACAM1 protein

NCBI chr 7:25,161,127...25,177,072
Ensembl chr 7:25,161,132...25,177,028

G

CEA cell adhesion molecule 20

decreases expression

alpha-Chlorohydrin results in decreased expression of CEACAM20 mRNA

NCBI chr 7:19,699,277...19,725,038
Ensembl chr 7:19,699,337...19,725,029

G

cell migration inducing protein, hyaluronan binding

increases expression

alpha-Chlorohydrin results in increased expression of CEMIP mRNA

NCBI chr 7:83,582,065...83,735,893
Ensembl chr 7:83,582,065...83,735,710

G

centrosomal protein 152

increases expression

alpha-Chlorohydrin results in increased expression of CEP152 mRNA

NCBI chr 2:125,391,784...125,467,081
Ensembl chr 2:125,405,008...125,467,033

G

centrosomal protein 55

increases expression

alpha-Chlorohydrin results in increased expression of CEP55 mRNA

NCBI chr19:38,043,423...38,062,873
Ensembl chr19:38,043,459...38,062,871

G

centrosomal protein 68

increases expression

alpha-Chlorohydrin results in increased expression of CEP68 protein

NCBI chr11:20,177,037...20,199,424
Ensembl chr11:20,177,037...20,199,429

G

carboxylesterase 1D

increases expression

alpha-Chlorohydrin analog results in increased expression of CES1 protein; alpha-Chlorohydrin results in increased expression of CES1 protein

NCBI chr 8:93,892,700...93,924,432
Ensembl chr 8:93,892,696...93,924,466

G

carboxylesterase 1G

decreases expression

alpha-Chlorohydrin results in decreased expression of CES1G mRNA

NCBI chr 8:94,028,997...94,063,837
Ensembl chr 8:94,028,997...94,063,936

G

CASP8 and FADD-like apoptosis regulator

increases expression

alpha-Chlorohydrin results in increased expression of CFLAR protein

NCBI chr 1:58,750,353...58,798,043
Ensembl chr 1:58,750,667...58,798,043

G

complement factor properdin

decreases expression

alpha-Chlorohydrin results in decreased expression of CFP mRNA

NCBI chr X:20,791,693...20,797,794
Ensembl chr X:20,791,693...20,797,794

G

ChaC, cation transport regulator 1

decreases expression

alpha-Chlorohydrin results in decreased expression of CHAC1 mRNA

NCBI chr 2:119,181,723...119,184,807
Ensembl chr 2:119,181,710...119,184,862

G

coiled-coil-helix-coiled-coil-helix domain containing 1

decreases expression

alpha-Chlorohydrin results in decreased expression of CHCHD1 mRNA

NCBI chr14:20,753,095...20,754,493
Ensembl chr14:20,753,074...20,754,493

G

cholinergic receptor, muscarinic 3, cardiac

decreases expression

alpha-Chlorohydrin results in decreased expression of CHRM3 mRNA

NCBI chr13:9,925,522...10,411,131
Ensembl chr13:9,925,522...10,410,883

G

CIMAP1 family member D

decreases expression

alpha-Chlorohydrin results in decreased expression of CIMAP1D mRNA

NCBI chr10:79,475,352...79,491,599
Ensembl chr10:79,475,360...79,481,572

G

cytoskeleton-associated protein 4

increases expression

alpha-Chlorohydrin results in increased expression of CKAP4 protein

NCBI chr10:84,362,169...84,369,752
Ensembl chr10:84,362,169...84,369,926

G

chloride channel, voltage-sensitive 7

decreases expression
multiple interactions

alpha-Chlorohydrin results in decreased expression of CLCN7 mRNA
ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in decreased expression of CLCN7 mRNA]

NCBI chr17:25,352,353...25,381,077
Ensembl chr17:25,352,365...25,381,078

G

claudin 1

increases expression

alpha-Chlorohydrin results in increased expression of CLDN1 mRNA; alpha-Chlorohydrin results in increased expression of CLDN1 protein

PMID:28522335 PMID:34915118

NCBI chr16:26,175,395...26,190,589
Ensembl chr16:26,175,392...26,190,591

G

claudin 17

decreases expression

alpha-Chlorohydrin results in decreased expression of CLDN17 mRNA

NCBI chr16:88,302,695...88,303,866
Ensembl chr16:88,302,695...88,303,866

G

claudin 8

decreases expression

alpha-Chlorohydrin results in decreased expression of CLDN8 mRNA

NCBI chr16:88,357,714...88,360,071
Ensembl chr16:88,357,716...88,360,071

G

C-type lectin domain family 2, member d

decreases expression

alpha-Chlorohydrin results in decreased expression of CLEC2D mRNA

NCBI chr 6:129,157,578...129,163,498
Ensembl chr 6:129,157,578...129,163,497

G

chloride intracellular channel 1

decreases expression

alpha-Chlorohydrin results in decreased expression of CLIC1 mRNA

NCBI chr17:35,269,219...35,277,695
Ensembl chr17:35,268,942...35,277,725

G

CAP-GLY domain containing linker protein 1

increases expression

alpha-Chlorohydrin results in increased expression of CLIP1 protein

NCBI chr 5:123,715,857...123,822,527
Ensembl chr 5:123,715,858...123,822,681

G

calmin

increases expression

alpha-Chlorohydrin results in increased expression of CLMN mRNA

NCBI chr12:104,729,373...104,831,335
Ensembl chr12:104,729,376...104,831,335

G

CLN3 lysosomal/endosomal transmembrane protein, battenin

increases expression

alpha-Chlorohydrin results in increased expression of CLN3 protein

NCBI chr 7:126,170,571...126,184,991
Ensembl chr 7:126,170,379...126,184,989

G

ClpB caseinolytic peptidase B

increases expression

alpha-Chlorohydrin results in increased expression of CLPB protein

NCBI chr 7:101,312,958...101,444,667
Ensembl chr 7:101,312,840...101,444,713

G

caseinolytic mitochondrial matrix peptidase chaperone subunit

decreases expression
increases expression

alpha-Chlorohydrin analog results in decreased expression of CLPX protein
alpha-Chlorohydrin results in increased expression of CLPX protein

PMID:26597043 PMID:34915118

NCBI chr 9:65,201,533...65,237,940
Ensembl chr 9:65,201,542...65,237,940

G

clarin 3

increases expression
decreases expression

alpha-Chlorohydrin results in increased expression of CLRN3 mRNA
alpha-Chlorohydrin results in decreased expression of CLRN3 protein

PMID:28522335 PMID:34915118

NCBI chr 7:135,113,185...135,130,383
Ensembl chr 7:135,113,195...135,130,383

G

clusterin

multiple interactions

[alpha-Chlorohydrin co-treated with glycidol] results in increased expression of CLU mRNA

NCBI chr14:66,206,093...66,218,992
Ensembl chr14:66,205,932...66,218,996

G

citrate lyase beta like

increases expression

alpha-Chlorohydrin results in increased expression of CLYBL mRNA

NCBI chr14:122,408,289...122,639,646
Ensembl chr14:122,419,116...122,639,646

G

cytidine monophospho-N-acetylneuraminic acid synthetase

increases expression

alpha-Chlorohydrin results in increased expression of CMAS protein

NCBI chr 6:142,702,468...142,721,440
Ensembl chr 6:142,702,412...142,721,440

G

carboxymethylenebutenolidase homolog

decreases expression

alpha-Chlorohydrin analog results in decreased expression of CMBL protein

NCBI chr15:31,565,314...31,590,266
Ensembl chr15:31,565,535...31,590,265

G

c-Maf inducing protein

increases expression

alpha-Chlorohydrin results in increased expression of CMIP mRNA

NCBI chr 8:117,983,758...118,188,245
Ensembl chr 8:117,983,803...118,186,169

G

CKLF-like MARVEL transmembrane domain containing 8

decreases expression

alpha-Chlorohydrin results in decreased expression of CMTM8 mRNA

NCBI chr 9:114,618,411...114,673,220
Ensembl chr 9:114,618,413...114,673,224

G

cornichon family AMPA receptor auxiliary protein 4

increases expression

alpha-Chlorohydrin results in increased expression of CNIH4 protein

NCBI chr 1:180,977,437...180,996,559
Ensembl chr 1:180,972,258...180,996,559

G

connector enhancer of kinase suppressor of Ras 1

decreases expression

alpha-Chlorohydrin results in decreased expression of CNKSR1 mRNA

NCBI chr 4:133,955,352...133,965,737
Ensembl chr 4:133,955,352...133,965,710

G

cyclin M2

decreases expression

alpha-Chlorohydrin results in decreased expression of CNNM2 protein

NCBI chr19:46,745,273...46,867,019
Ensembl chr19:46,750,035...46,868,631

G

cyclin M4

increases expression

alpha-Chlorohydrin results in increased expression of CNNM4 protein

NCBI chr 1:36,510,678...36,547,857
Ensembl chr 1:36,510,701...36,547,845

G

CCR4-NOT transcription complex, subunit 10

increases expression

alpha-Chlorohydrin results in increased expression of CNOT10 protein

NCBI chr 9:114,414,942...114,469,289
Ensembl chr 9:114,414,946...114,469,252

G

2',3'-cyclic nucleotide 3' phosphodiesterase

increases expression

alpha-Chlorohydrin results in increased expression of CNP protein

NCBI chr11:100,465,765...100,472,565
Ensembl chr11:100,465,730...100,482,555

G

cordon-bleu WH2 repeat

increases expression

alpha-Chlorohydrin results in increased expression of COBL mRNA

NCBI chr11:12,186,676...12,415,022
Ensembl chr11:12,186,608...12,414,960

G

component of oligomeric golgi complex 4

increases expression

alpha-Chlorohydrin results in increased expression of COG4 protein

NCBI chr 8:111,573,232...111,608,866
Ensembl chr 8:111,573,232...111,608,859

G

collagen, type XXVII, alpha 1

multiple interactions

[alpha-Chlorohydrin co-treated with glycidol] results in decreased expression of COL27A1 mRNA

NCBI chr 4:63,132,246...63,253,228
Ensembl chr 4:63,132,241...63,253,228

G

collagen, type IV, alpha 1

increases expression

alpha-Chlorohydrin results in increased expression of COL4A1 protein

NCBI chr 8:11,248,423...11,362,889
Ensembl chr 8:11,248,423...11,362,826

G

collagen, type V, alpha 2

decreases expression

alpha-Chlorohydrin results in decreased expression of COL5A2 mRNA

NCBI chr 1:45,413,491...45,542,442
Ensembl chr 1:45,413,481...45,542,442

G

collagen, type VI, alpha 1

increases expression

alpha-Chlorohydrin results in increased expression of COL6A1 mRNA

NCBI chr10:76,544,626...76,561,869
Ensembl chr10:76,544,626...76,562,002

G

collagen beta(1-O)galactosyltransferase 1

increases expression

alpha-Chlorohydrin results in increased expression of COLGALT1 protein

NCBI chr 8:72,063,631...72,077,555
Ensembl chr 8:72,063,642...72,077,555

G

catechol-O-methyltransferase

decreases expression

alpha-Chlorohydrin analog results in decreased expression of COMT protein; alpha-Chlorohydrin results in decreased expression of COMT protein

NCBI chr16:18,225,632...18,247,006
Ensembl chr16:18,225,636...18,245,602

G

catechol-O-methyltransferase domain containing 1

increases expression

alpha-Chlorohydrin results in increased expression of COMTD1 protein

NCBI chr14:21,895,929...21,898,978
Ensembl chr14:21,895,923...21,899,045

G

coatomer protein complex, subunit zeta 2

increases expression

alpha-Chlorohydrin results in increased expression of COPZ2 mRNA

NCBI chr11:96,740,702...96,752,029
Ensembl chr11:96,740,696...96,752,029

G

coenzyme Q10A

decreases expression

alpha-Chlorohydrin results in decreased expression of COQ10A protein

NCBI chr10:128,198,965...128,204,849
Ensembl chr10:128,198,969...128,204,866

G

coenzyme Q10B

decreases expression

alpha-Chlorohydrin results in decreased expression of COQ10B protein

NCBI chr 1:55,091,929...55,111,861
Ensembl chr 1:55,091,929...55,111,861

G

coenzyme Q3 methyltransferase

increases expression

alpha-Chlorohydrin results in increased expression of COQ3 protein

NCBI chr 4:21,879,646...21,912,163
Ensembl chr 4:21,879,673...21,912,162

G

coenzyme Q8B

increases expression

alpha-Chlorohydrin results in increased expression of COQ8B protein

NCBI chr 7:26,928,112...26,957,374
Ensembl chr 7:26,932,448...26,957,375

G

coronin, actin binding protein 1A

increases expression

alpha-Chlorohydrin results in increased expression of CORO1A protein

NCBI chr 7:126,298,946...126,303,925
Ensembl chr 7:126,298,945...126,306,959

G

cytochrome c oxidase assembly protein 14

decreases expression

alpha-Chlorohydrin results in decreased expression of COX14 mRNA

NCBI chr15:99,623,499...99,626,017
Ensembl chr15:99,623,528...99,627,413

G

cytochrome c oxidase assembly protein 17, copper chaperone

decreases expression
multiple interactions
increases expression
affects expression

alpha-Chlorohydrin results in decreased expression of COX17 protein
Apigenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of COX17 mRNA]; Apigenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of COX17 protein]
alpha-Chlorohydrin results in increased expression of COX17 mRNA; alpha-Chlorohydrin results in increased expression of COX17 protein
alpha-Chlorohydrin affects the expression of COX17 mRNA

PMID:27732882 PMID:30107153

NCBI chr16:38,167,332...38,173,125
Ensembl chr16:38,167,353...38,182,659

G

copine III

increases expression

alpha-Chlorohydrin results in increased expression of CPNE3 mRNA

NCBI chr 4:19,519,252...19,570,108
Ensembl chr 4:19,519,254...19,570,108

G

coproporphyrinogen oxidase

increases expression

alpha-Chlorohydrin results in increased expression of CPOX protein

NCBI chr16:58,490,571...58,500,754
Ensembl chr16:58,490,655...58,537,999

G

carboxypeptidase Q

decreases expression

alpha-Chlorohydrin results in decreased expression of CPQ protein

NCBI chr15:33,083,275...33,594,698
Ensembl chr15:33,083,275...33,594,698

G

carbamoyl-phosphate synthetase 1

decreases expression
affects expression

alpha-Chlorohydrin results in decreased expression of CPS1 protein
alpha-Chlorohydrin analog affects the expression of CPS1 protein

NCBI chr 1:67,151,294...67,270,426
Ensembl chr 1:67,162,185...67,270,418

G

cleavage and polyadenylation specific factor 2

increases expression

alpha-Chlorohydrin results in increased expression of CPSF2 protein

NCBI chr12:101,940,345...101,972,252
Ensembl chr12:101,942,247...101,972,683

G

cleavage and polyadenylation specific factor 6

increases expression

alpha-Chlorohydrin results in increased expression of CPSF6 protein

NCBI chr10:117,180,572...117,212,903
Ensembl chr10:117,180,578...117,215,920

G

carnitine palmitoyltransferase 1a, liver

increases expression

alpha-Chlorohydrin results in increased expression of CPT1A mRNA

NCBI chr19:3,372,328...3,435,735
Ensembl chr19:3,372,334...3,435,733

G

carnitine palmitoyltransferase 2

affects expression

alpha-Chlorohydrin analog affects the expression of CPT2 protein

NCBI chr 4:107,761,179...107,780,786
Ensembl chr 4:107,761,178...107,780,807

G

CASP2 and RIPK1 domain containing adaptor with death domain

decreases expression

alpha-Chlorohydrin results in decreased expression of CRADD mRNA

NCBI chr10:95,010,601...95,160,000
Ensembl chr10:95,010,608...95,159,995

G

cAMP responsive element binding protein 1

decreases phosphorylation

alpha-Chlorohydrin results in decreased phosphorylation of CREB1 protein

NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707

G

cellular repressor of E1A-stimulated genes 1

increases expression

alpha-Chlorohydrin results in increased expression of CREG1 protein

NCBI chr 1:165,591,327...165,602,878
Ensembl chr 1:165,591,315...165,602,877

G

cartilage associated protein

increases expression

alpha-Chlorohydrin results in increased expression of CRTAP mRNA

NCBI chr 9:114,204,204...114,219,743
Ensembl chr 9:114,204,202...114,219,743

G

cryptochrome circadian regulator 1

decreases expression

alpha-Chlorohydrin results in decreased expression of CRY1 mRNA

NCBI chr10:84,967,564...85,020,918
Ensembl chr10:84,967,564...85,020,928

G

crystallin, alpha B

multiple interactions

[alpha-Chlorohydrin co-treated with glycidol] results in increased expression of CRYAB mRNA

NCBI chr 9:50,657,251...50,667,936
Ensembl chr 9:50,662,625...50,667,936

G

crystallin, lambda 1

increases expression

alpha-Chlorohydrin results in increased expression of CRYL1 mRNA

NCBI chr14:57,512,491...57,635,940
Ensembl chr14:57,512,450...57,635,986

G

crystallin, mu

decreases expression

alpha-Chlorohydrin results in decreased expression of CRYM mRNA

NCBI chr 7:119,785,603...119,801,212
Ensembl chr 7:119,785,603...119,801,334

G

cysteine sulfinic acid decarboxylase

increases expression

alpha-Chlorohydrin analog results in increased expression of CSAD protein; alpha-Chlorohydrin results in increased expression of CSAD protein

NCBI chr15:102,085,432...102,112,685
Ensembl chr15:102,085,434...102,113,159

G

c-src tyrosine kinase

increases expression

alpha-Chlorohydrin results in increased expression of CSK protein

NCBI chr 9:57,533,929...57,560,758
Ensembl chr 9:57,533,929...57,560,914

G

cysteine-serine-rich nuclear protein 3

decreases expression

alpha-Chlorohydrin results in decreased expression of H3C8 mRNA

NCBI chr 2:65,675,628...65,866,958
Ensembl chr 2:65,676,111...65,861,890

G

cysteine and glycine-rich protein 1

increases expression

alpha-Chlorohydrin results in increased expression of CSRP1 mRNA; alpha-Chlorohydrin results in increased expression of CSRP1 protein

PMID:28522335 PMID:34915118

NCBI chr 1:135,614,650...135,679,970
Ensembl chr 1:135,647,799...135,679,970

G

cystatin C

decreases expression
multiple interactions

alpha-Chlorohydrin results in decreased expression of CST3 mRNA
4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of and affects the localization of CST3 protein]; alpha-Chlorohydrin results in increased expression of and affects the localization of CST3 protein

PMID:28522335 PMID:33651226

NCBI chr 2:148,713,642...148,717,432
Ensembl chr 2:148,713,642...148,717,612

G

cystatin E/M

decreases expression

alpha-Chlorohydrin results in decreased expression of CST6 protein

NCBI chr19:5,394,733...5,399,602
Ensembl chr19:5,394,733...5,399,602

G

cystatin B

decreases expression

alpha-Chlorohydrin results in decreased expression of CSTB mRNA

NCBI chr10:78,261,504...78,263,456
Ensembl chr10:78,261,503...78,263,456

G

cystathionine gamma lyase

affects expression
increases expression

alpha-Chlorohydrin affects the expression of CTH protein
alpha-Chlorohydrin analog results in increased expression of CTH protein

NCBI chr 3:157,599,885...157,630,718
Ensembl chr 3:157,599,885...157,630,714

G

cystinosis, nephropathic

increases expression

alpha-Chlorohydrin results in increased expression of CTNS mRNA

NCBI chr11:73,073,959...73,089,869
Ensembl chr11:73,074,422...73,089,868

G

cytidine 5'-triphosphate synthase 1

increases expression

alpha-Chlorohydrin results in increased expression of CTPS1 protein

NCBI chr 4:120,397,065...120,427,473
Ensembl chr 4:120,397,065...120,427,473

G

cathepsin B

decreases expression
multiple interactions

alpha-Chlorohydrin results in decreased expression of CTSB mRNA
ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in decreased expression of CTSB mRNA]

PMID:32702505 PMID:34812491

NCBI chr14:63,359,911...63,383,372
Ensembl chr14:63,359,911...63,383,372

G

cathepsin C

increases expression

alpha-Chlorohydrin results in increased expression of CTSC mRNA

NCBI chr 7:87,927,233...87,960,083
Ensembl chr 7:87,927,293...87,960,096

G

cathepsin D

decreases expression
multiple interactions

alpha-Chlorohydrin results in decreased expression of CTSD mRNA
ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in decreased expression of CTSD mRNA]

NCBI chr 7:141,929,647...141,941,564
Ensembl chr 7:141,929,648...141,941,775

G

cathepsin S

decreases expression

alpha-Chlorohydrin results in decreased expression of CTSS mRNA

NCBI chr 3:95,434,097...95,463,716
Ensembl chr 3:95,434,097...95,463,714

G

cathepsin Z

decreases expression

alpha-Chlorohydrin results in decreased expression of CTSZ mRNA

NCBI chr 2:174,269,287...174,280,832
Ensembl chr 2:174,269,286...174,280,832

G

cullin 2

decreases expression

alpha-Chlorohydrin results in decreased expression of CUL2 mRNA

NCBI chr18:3,382,970...3,436,700
Ensembl chr18:3,382,988...3,436,377

G

CWC22 spliceosome-associated protein

increases expression

alpha-Chlorohydrin results in increased expression of CWC22 protein

NCBI chr 2:77,706,312...77,776,705
Ensembl chr 2:77,711,503...77,776,719

G

C-X-C motif chemokine ligand 13

increases expression
decreases expression

alpha-Chlorohydrin results in increased expression of CXCL13 mRNA
alpha-Chlorohydrin results in decreased expression of CXCL13 mRNA

PMID:20409345 PMID:28522335

NCBI chr 5:96,104,785...96,108,927
Ensembl chr 5:96,104,810...96,108,927

G

C-X-C motif chemokine ligand 2

multiple interactions
increases expression

MLKL protein affects the reaction [alpha-Chlorohydrin analog results in increased expression of CXCL2 mRNA]; RIPK3 protein affects the reaction [alpha-Chlorohydrin analog results in increased expression of CXCL2 mRNA]

NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797

G

C-X-C motif chemokine ligand 3

increases expression
multiple interactions

alpha-Chlorohydrin analog results in increased expression of CXCL1 mRNA
MLKL protein affects the reaction [alpha-Chlorohydrin analog results in increased expression of CXCL1 mRNA]; RIPK3 protein affects the reaction [alpha-Chlorohydrin analog results in increased expression of CXCL1 mRNA]

NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459

G

C-X-C motif chemokine ligand 9

decreases expression

alpha-Chlorohydrin results in decreased expression of CXCL9 mRNA

NCBI chr 5:92,469,190...92,475,938
Ensembl chr 5:92,469,206...92,475,938

G

cytochrome b5 reductase 1

increases expression

alpha-Chlorohydrin results in increased expression of CYB5R1 protein

NCBI chr 1:134,333,519...134,339,476
Ensembl chr 1:134,333,297...134,339,478

G

cytochrome b5 reductase 3

increases expression

alpha-Chlorohydrin results in increased expression of CYB5R3 mRNA

NCBI chr15:83,037,696...83,060,641
Ensembl chr15:83,037,695...83,056,793

G

cytochrome b5 reductase 4

increases expression

alpha-Chlorohydrin results in increased expression of CYB5R4 protein

NCBI chr 9:86,904,082...86,959,827
Ensembl chr 9:86,904,067...86,959,827

G

cytochrome b-245, alpha polypeptide

affects expression

alpha-Chlorohydrin affects the expression of CYBA mRNA

NCBI chr 8:123,151,510...123,159,679
Ensembl chr 8:123,151,515...123,159,669

G

cytochrome c, somatic

increases expression

alpha-Chlorohydrin results in increased expression of CYCS mRNA; alpha-Chlorohydrin results in increased expression of CYCS protein

NCBI chr 6:50,539,543...50,543,549
Ensembl chr 6:50,539,543...50,543,518

G

cytoplasmic FMR1 interacting protein 2

decreases expression

alpha-Chlorohydrin results in decreased expression of CYFIP2 mRNA

NCBI chr11:46,084,676...46,203,686
Ensembl chr11:46,084,677...46,203,686

G

cytoglobin

increases expression

alpha-Chlorohydrin results in increased expression of CYGB mRNA; alpha-Chlorohydrin results in increased expression of CYGB protein

PMID:28522335 PMID:34915118

NCBI chr11:116,536,421...116,544,887
Ensembl chr11:116,536,421...116,545,139

G

cytochrome P450, family 11, subfamily a, polypeptide 1

increases expression

alpha-Chlorohydrin results in increased expression of CYP11A1 mRNA

NCBI chr 9:57,905,307...57,934,314
Ensembl chr 9:57,913,694...57,934,306

G

cytochrome P450, family 17, subfamily a, polypeptide 1

increases expression

alpha-Chlorohydrin results in increased expression of CYP17A1 mRNA

NCBI chr19:46,655,604...46,661,439
Ensembl chr19:46,655,604...46,661,611

G

cytochrome P450, family 24, subfamily a, polypeptide 1

decreases expression

alpha-Chlorohydrin results in decreased expression of CYP24A1 mRNA

NCBI chr 2:170,324,877...170,339,065
Ensembl chr 2:170,324,628...170,339,065

G

cytochrome P450, family 2, subfamily b, polypeptide 10

decreases expression

alpha-Chlorohydrin results in decreased expression of CYP2B6 mRNA

NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049

G

cytochrome P450, family 2, subfamily e, polypeptide 1

decreases expression

alpha-Chlorohydrin results in decreased expression of CYP2E1 protein

NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900

G

cytochrome P450, family 2, subfamily j, polypeptide 9

increases expression

alpha-Chlorohydrin results in increased expression of CYP2J4 mRNA

NCBI chr 4:96,456,661...96,480,748
Ensembl chr 4:96,456,666...96,479,815

G

cytochrome P450, family 4, subfamily a, polypeptide 12a

decreases expression

alpha-Chlorohydrin results in decreased expression of CYP4A12A mRNA

NCBI chr 4:115,156,243...115,190,012
Ensembl chr 4:115,156,243...115,190,012

G

cytochrome P450, family 4, subfamily b, polypeptide 1

multiple interactions

[alpha-Chlorohydrin co-treated with glycidol] results in decreased expression of CYP4B1 mRNA

NCBI chr 4:115,481,895...115,504,918
Ensembl chr 4:115,481,922...115,504,920

G

cytochrome P450, family 4, subfamily v, polypeptide 3

decreases expression

alpha-Chlorohydrin results in decreased expression of CYP4V3 mRNA

NCBI chr 8:45,758,838...45,786,200
Ensembl chr 8:45,757,981...45,786,253

G

cytochrome P450, family 7, subfamily b, polypeptide 1

increases expression

alpha-Chlorohydrin results in increased expression of CYP7B1 protein

NCBI chr 3:18,126,108...18,298,054
Ensembl chr 3:18,126,114...18,297,502

G

cystin 1

increases expression

alpha-Chlorohydrin results in increased expression of CYS1 mRNA

NCBI chr12:24,715,832...24,731,794
Ensembl chr12:24,715,832...24,731,812

G

CXXC motif containing zinc binding protein

decreases expression

alpha-Chlorohydrin results in decreased expression of CZIB protein

NCBI chr 4:107,746,982...107,755,000
Ensembl chr 4:107,747,010...107,756,581

G

DNA segment, Chr 6, Wayne State University 163, expressed

increases expression

alpha-Chlorohydrin results in increased expression of FERRY3 protein

NCBI chr 6:126,916,938...126,952,667
Ensembl chr 6:126,916,925...126,952,930

G

D-amino acid oxidase

decreases expression

alpha-Chlorohydrin results in decreased expression of DAO protein

NCBI chr 5:114,137,696...114,163,736
Ensembl chr 5:114,141,764...114,163,743

G

death-associated protein

increases expression

alpha-Chlorohydrin results in increased expression of DAP mRNA

NCBI chr15:31,224,531...31,274,484
Ensembl chr15:31,224,460...31,274,487

G

death associated protein 3

increases expression

alpha-Chlorohydrin results in increased expression of DAP3 protein

NCBI chr 3:88,828,110...88,858,504
Ensembl chr 3:88,828,110...88,858,488

G

death associated protein kinase 1

decreases expression

alpha-Chlorohydrin results in decreased expression of DAPK1 mRNA

NCBI chr13:60,749,506...60,911,005
Ensembl chr13:60,749,761...60,911,005

G

aspartyl-tRNA synthetase 1

increases expression

alpha-Chlorohydrin results in increased expression of DARS1 protein

NCBI chr 1:128,291,444...128,345,153
Ensembl chr 1:128,291,444...128,345,105

G

dihydrolipoamide branched chain transacylase E2

decreases expression

alpha-Chlorohydrin results in decreased expression of DBT protein

NCBI chr 3:116,306,776...116,343,630
Ensembl chr 3:116,306,719...116,343,630

G

DDB1 and CUL4 associated factor 11

increases expression

alpha-Chlorohydrin results in increased expression of DCAF11 protein

NCBI chr14:55,796,557...55,807,522
Ensembl chr14:55,797,463...55,807,522

G

deoxycytidine kinase

decreases expression

alpha-Chlorohydrin analog results in decreased expression of DCK protein; alpha-Chlorohydrin results in decreased expression of DCK protein

NCBI chr 5:88,912,872...88,931,136
Ensembl chr 5:88,912,855...88,931,140

G

decorin

affects expression

alpha-Chlorohydrin affects the expression of DCN mRNA

NCBI chr10:97,315,362...97,354,025
Ensembl chr10:97,315,471...97,354,005

G

dynactin 2

decreases expression

alpha-Chlorohydrin analog results in decreased expression of DCTN2 protein; alpha-Chlorohydrin results in decreased expression of DCTN2 protein

NCBI chr10:127,102,131...127,117,828
Ensembl chr10:127,102,237...127,117,819

G

dicarbonyl L-xylulose reductase

decreases expression

alpha-Chlorohydrin results in decreased expression of DCXR protein

NCBI chr11:120,615,372...120,618,110
Ensembl chr11:120,616,225...120,618,107

G

dimethylarginine dimethylaminohydrolase 1

increases expression

alpha-Chlorohydrin results in increased expression of DDAH1 mRNA

NCBI chr 3:145,464,447...145,600,032
Ensembl chr 3:145,464,430...145,600,032

G

DNA-damage inducible transcript 3

multiple interactions
increases phosphorylation

4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased phosphorylation of DDIT3 protein]

NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157

G

dolichyl-di-phosphooligosaccharide-protein glycotransferase

increases expression

alpha-Chlorohydrin analog results in increased expression of DDOST protein; alpha-Chlorohydrin results in increased expression of DDOST protein

NCBI chr 4:138,032,049...138,039,930
Ensembl chr 4:138,032,041...138,039,939

G

D-dopachrome tautomerase

increases expression

alpha-Chlorohydrin results in increased expression of DDT mRNA

NCBI chr10:75,607,067...75,609,208
Ensembl chr10:75,607,064...75,609,248

G

DEAD box helicase 18

increases expression

alpha-Chlorohydrin results in increased expression of DDX18 protein

NCBI chr 1:121,481,564...121,495,709
Ensembl chr 1:121,481,564...121,495,718

G

DEAD box helicase 19a

increases expression

alpha-Chlorohydrin results in increased expression of DDX19A mRNA

NCBI chr 8:111,701,623...111,724,456
Ensembl chr 8:111,701,628...111,724,432

G

DEAD box helicase 23

increases expression

alpha-Chlorohydrin results in increased expression of DDX23 protein

NCBI chr15:98,543,012...98,560,808
Ensembl chr15:98,543,015...98,560,775

G

DEAD box helicase 39b

increases expression

alpha-Chlorohydrin analog results in increased expression of BAT1 protein; alpha-Chlorohydrin results in increased expression of BAT1 protein

NCBI chr17:35,460,722...35,472,683
Ensembl chr17:35,460,722...35,472,683

G

DEAD box helicase 4

decreases expression

alpha-Chlorohydrin results in decreased expression of DDX4 protein

NCBI chr13:112,734,867...112,790,342
Ensembl chr13:112,734,867...112,789,009

G

DEAD box helicase 41

increases expression

alpha-Chlorohydrin results in increased expression of DDX41 protein

NCBI chr13:55,678,223...55,684,471
Ensembl chr13:55,678,223...55,684,471

G

DEAD box helicase 47

increases expression

alpha-Chlorohydrin results in increased expression of DDX47 protein

NCBI chr 6:134,988,575...135,000,739
Ensembl chr 6:134,988,575...135,000,739

G

DExD box helicase 50

increases expression

alpha-Chlorohydrin results in increased expression of DDX50 protein

NCBI chr10:62,451,571...62,487,260
Ensembl chr10:62,451,674...62,486,997

G

DExD box helicase 52

increases expression

alpha-Chlorohydrin results in increased expression of DDX52 protein

NCBI chr11:83,831,659...83,853,914
Ensembl chr11:83,832,888...83,853,914

G

DEAD box helicase 59

increases expression

alpha-Chlorohydrin results in increased expression of DDX59 protein

NCBI chr 1:136,343,009...136,384,019
Ensembl chr 1:136,343,009...136,367,896

G

2-4-dienoyl-Coenzyme A reductase 2, peroxisomal

decreases expression

alpha-Chlorohydrin results in decreased expression of DECR2 protein

NCBI chr17:26,300,182...26,309,096
Ensembl chr17:26,300,182...26,309,311

G

defensin beta 1

decreases expression

alpha-Chlorohydrin results in decreased expression of DEFB1 mRNA

NCBI chr 8:22,266,571...22,285,201
Ensembl chr 8:22,266,615...22,285,201

G

DEPP1 autophagy regulator

multiple interactions

[alpha-Chlorohydrin co-treated with glycidol] results in increased expression of DEPP1 mRNA

NCBI chr 6:116,627,645...116,629,808
Ensembl chr 6:116,627,570...116,629,755

G

desmin

increases expression

alpha-Chlorohydrin results in increased expression of DES protein

NCBI chr 1:75,336,936...75,345,223
Ensembl chr 1:75,336,973...75,345,223

G

dehydrogenase/reductase 1

decreases expression

alpha-Chlorohydrin results in decreased expression of DHRS1 protein

NCBI chr14:55,976,477...55,983,147
Ensembl chr14:55,976,477...55,983,147

G

dehydrogenase/reductase 7B

increases expression

alpha-Chlorohydrin results in increased expression of DHRS7B protein

NCBI chr11:60,721,457...60,749,249
Ensembl chr11:60,721,457...60,751,021

G

dehydrogenase E1 and transketolase domain containing 1

decreases expression

alpha-Chlorohydrin results in decreased expression of DHTKD1 protein

NCBI chr 2:5,901,030...5,947,648
Ensembl chr 2:5,900,926...5,947,603

G

DExH-box helicase 30

increases expression

alpha-Chlorohydrin results in increased expression of DHX30 protein

NCBI chr 9:109,913,387...109,946,728
Ensembl chr 9:109,913,388...109,946,898

G

diaphanous related formin 1

increases expression

alpha-Chlorohydrin results in increased expression of DIAPH1 protein

NCBI chr18:37,976,654...38,068,573
Ensembl chr18:37,976,654...38,068,529

G

deiodinase, iodothyronine, type I

decreases expression

alpha-Chlorohydrin results in decreased expression of DIO1 protein

NCBI chr 4:107,148,662...107,164,365
Ensembl chr 4:107,148,662...107,164,366

G

divergent protein kinase domain 1A

increases expression

alpha-Chlorohydrin results in increased expression of DIPK1A mRNA

NCBI chr 5:108,055,908...108,134,943
Ensembl chr 5:108,055,919...108,134,951

G

dyskeratosis congenita 1, dyskerin

increases expression

alpha-Chlorohydrin results in increased expression of DKC1 protein

NCBI chr X:74,139,460...74,153,382
Ensembl chr X:74,139,460...74,153,383

G

delta like canonical Notch ligand 4

decreases expression

alpha-Chlorohydrin results in decreased expression of DLL4 mRNA

NCBI chr 2:119,156,286...119,166,145
Ensembl chr 2:119,156,265...119,166,443

G

distal membrane arm assembly complex 2

increases expression

alpha-Chlorohydrin results in increased expression of DMAC2 protein

NCBI chr 7:25,318,839...25,324,975
Ensembl chr 7:25,318,839...25,324,976

G

dimethylglycine dehydrogenase precursor

increases expression

alpha-Chlorohydrin analog results in increased expression of DMGDH protein

NCBI chr13:93,810,944...93,889,331
Ensembl chr13:93,810,941...93,889,341

G

DnaJ heat shock protein family (Hsp40) member B1

increases expression

alpha-Chlorohydrin results in increased expression of DNAJB1 protein

NCBI chr 8:84,334,804...84,339,282
Ensembl chr 8:84,334,822...84,339,282

G

DnaJ heat shock protein family (Hsp40) member B2

increases expression

alpha-Chlorohydrin results in increased expression of DNAJB2 protein

NCBI chr 1:75,213,039...75,222,336
Ensembl chr 1:75,213,050...75,222,336

G

DnaJ heat shock protein family (Hsp40) member B4

increases expression

alpha-Chlorohydrin results in increased expression of DNAJB4 protein

NCBI chr 3:151,887,217...151,915,720
Ensembl chr 3:151,884,148...151,915,939

G

DnaJ heat shock protein family (Hsp40) member B6

increases expression

alpha-Chlorohydrin results in increased expression of DNAJB6 protein

NCBI chr 5:29,940,896...29,991,476
Ensembl chr 5:29,940,686...30,023,132

G

DnaJ heat shock protein family (Hsp40) member C3

decreases expression

alpha-Chlorohydrin analog results in decreased expression of DNAJC3 protein; alpha-Chlorohydrin results in decreased expression of DNAJC3 protein

NCBI chr14:119,175,371...119,219,114
Ensembl chr14:119,175,388...119,219,109

G

DnaJ heat shock protein family (Hsp40) member C5 beta

decreases expression

alpha-Chlorohydrin results in decreased expression of DNAJC5B mRNA

NCBI chr 3:19,562,755...19,665,026
Ensembl chr 3:19,562,759...19,665,026

G

DnaJ heat shock protein family (Hsp40) member C6

increases expression

alpha-Chlorohydrin results in increased expression of DNAJC6 mRNA

NCBI chr 4:101,353,751...101,499,996
Ensembl chr 4:101,353,828...101,499,996

G

DnaJ heat shock protein family (Hsp40) member C8

increases expression

alpha-Chlorohydrin results in increased expression of DNAJC8 protein

NCBI chr 4:132,262,859...132,281,053
Ensembl chr 4:132,262,861...132,281,053

G

deoxyribonuclease I

multiple interactions

[alpha-Chlorohydrin co-treated with glycidol] results in decreased expression of DNASE1 mRNA

NCBI chr16:3,855,007...3,857,888
Ensembl chr16:3,854,806...3,857,888

G

deoxyribonuclease 1-like 3

increases expression

alpha-Chlorohydrin results in increased expression of DNASE1L3 mRNA

PMID:20409345 PMID:28522335

NCBI chr14:14,475,014...14,504,586
Ensembl chr14:14,475,200...14,505,240

G

deoxyribonuclease II alpha

decreases expression

alpha-Chlorohydrin results in decreased expression of DNASE2 mRNA; alpha-Chlorohydrin results in decreased expression of DNASE2 protein

PMID:28522335 PMID:34915118

NCBI chr 8:85,635,384...85,638,332
Ensembl chr 8:85,635,189...85,649,544

G

dynamin 1-like

increases phosphorylation
increases expression
affects localization
multiple interactions

alpha-Chlorohydrin results in increased phosphorylation of DNM1L protein
alpha-Chlorohydrin results in increased expression of DNM1L protein
alpha-Chlorohydrin affects the localization of DNM1L protein
4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of and results in increased phosphorylation of DNM1L protein]; alpha-Chlorohydrin results in increased expression of and results in increased phosphorylation of DNM1L protein; Diosgenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of DNM1L protein]
4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of and affects the localization of DNM1L protein]; 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased phosphorylation of DNM1L protein]; alpha-Chlorohydrin results in increased expression of and affects the localization of DNM1L protein; Diosgenin affects the reaction [alpha-Chlorohydrin affects the localization of DNM1L protein]

PMID:33651226 PMID:35149085

NCBI chr16:16,130,092...16,176,863
Ensembl chr16:16,130,094...16,176,823

G

2'-deoxynucleoside 5'-phosphate N-hydrolase 1

decreases expression

alpha-Chlorohydrin results in decreased expression of DNPH1 protein

NCBI chr17:46,807,715...46,810,544
Ensembl chr17:46,807,637...46,810,550

G

dedicator of cyto-kinesis 2

decreases expression

alpha-Chlorohydrin results in decreased expression of DOCK2 mRNA

NCBI chr11:34,176,815...34,674,732
Ensembl chr11:34,176,815...34,674,719

G

dedicator of cytokinesis 9

increases expression

alpha-Chlorohydrin results in increased expression of DOCK9 protein

NCBI chr14:121,772,026...122,038,465
Ensembl chr14:121,779,458...122,035,249

G

docking protein 1

increases expression

alpha-Chlorohydrin results in increased expression of DOK1 protein

NCBI chr 6:83,007,915...83,010,448
Ensembl chr 6:83,007,915...83,010,452

G

DPH2 homolog

increases expression

alpha-Chlorohydrin results in increased expression of DPH2 protein

NCBI chr 4:117,745,838...117,749,220
Ensembl chr 4:117,745,840...117,749,229

G

diphthamide biosynthesis 5

increases expression

alpha-Chlorohydrin results in increased expression of DPH5 protein

NCBI chr 3:115,681,785...115,728,010
Ensembl chr 3:115,681,486...115,728,010

G

dipeptidylpeptidase 7

increases expression

alpha-Chlorohydrin results in increased expression of DPP7 mRNA

NCBI chr 2:25,242,302...25,246,365
Ensembl chr 2:25,242,288...25,246,371

G

dihydropyrimidinase

increases expression
decreases expression

alpha-Chlorohydrin analog results in increased expression of DPYS protein; alpha-Chlorohydrin results in increased expression of DPYS protein
alpha-Chlorohydrin results in decreased expression of DPYS protein

PMID:26597043 PMID:34915118

NCBI chr15:39,631,881...39,720,866
Ensembl chr15:39,631,883...39,720,866

G

DNA-damage regulated autophagy modulator 2

increases expression

alpha-Chlorohydrin results in increased expression of DRAM2 mRNA

NCBI chr 3:106,455,114...106,482,657
Ensembl chr 3:106,455,114...106,483,206

G

DR1 associated protein 1

increases expression

alpha-Chlorohydrin results in increased expression of DRAP1 protein

NCBI chr19:5,472,832...5,475,007
Ensembl chr19:5,472,833...5,475,007

G

dermatan sulfate epimerase-like

increases expression

alpha-Chlorohydrin results in increased expression of DSEL mRNA

NCBI chr 1:111,786,431...111,792,782
Ensembl chr 1:111,786,432...111,792,648

G

desmoplakin

increases expression

alpha-Chlorohydrin results in increased expression of DSP protein

NCBI chr13:38,335,357...38,382,553
Ensembl chr13:38,335,270...38,382,553

G

dual specificity phosphatase 12

increases expression

alpha-Chlorohydrin results in increased expression of DUSP12 mRNA

NCBI chr 1:170,701,756...170,713,109
Ensembl chr 1:170,701,067...170,713,109

G

dual specificity phosphatase 6

decreases expression

alpha-Chlorohydrin results in decreased expression of DUSP6 mRNA

NCBI chr10:99,098,676...99,103,351
Ensembl chr10:99,099,093...99,103,351

G

dual specificity phosphatase 7

increases expression

alpha-Chlorohydrin results in increased expression of DUSP7 mRNA

NCBI chr 9:106,245,831...106,252,923
Ensembl chr 9:106,245,831...106,252,923

G

dynein cytoplasmic 1 intermediate chain 2

increases expression

alpha-Chlorohydrin results in increased expression of DYNC1I2 protein

NCBI chr 2:71,041,999...71,093,647
Ensembl chr 2:71,042,050...71,093,647

G

dynein, cytoplasmic 1 light intermediate chain 2

increases expression

alpha-Chlorohydrin results in increased expression of DYNC1LI2 protein

NCBI chr 8:105,144,306...105,170,415
Ensembl chr 8:105,144,312...105,169,679

G

dynein light chain Tctex-type 1B

increases expression

alpha-Chlorohydrin results in increased expression of DYNLT1 protein

NCBI chr17:6,697,511...6,703,695
Ensembl chr17:6,697,511...6,703,695

G

enoyl Coenzyme A hydratase, short chain, 1, mitochondrial

increases expression

alpha-Chlorohydrin results in increased expression of ECHS1 mRNA

NCBI chr 7:139,685,623...139,696,334
Ensembl chr 7:139,685,623...139,696,389

G

enoyl-Coenzyme A delta isomerase 1

decreases expression

alpha-Chlorohydrin results in decreased expression of ECI1 protein

NCBI chr17:24,645,657...24,658,290
Ensembl chr17:24,645,615...24,658,322

G

extracellular matrix protein 1

increases expression

alpha-Chlorohydrin results in increased expression of ECM1 mRNA

NCBI chr 3:95,641,459...95,646,880
Ensembl chr 3:95,641,459...95,646,881

G

ER degradation enhancer, mannosidase alpha-like 3

increases expression

alpha-Chlorohydrin results in increased expression of EDEM3 protein

NCBI chr 1:151,631,099...151,698,079
Ensembl chr 1:151,631,122...151,697,802

G

erythroid differentiation regulatory factor 1

increases expression

alpha-Chlorohydrin results in increased expression of EDRF1 mRNA

NCBI chr 7:133,239,422...133,274,710
Ensembl chr 7:133,239,272...133,274,700

G

EEF1A lysine methyltransferase 3

increases expression

alpha-Chlorohydrin results in increased expression of EEF1AKMT3 mRNA

NCBI chr10:126,868,654...126,877,883
Ensembl chr10:126,866,873...126,877,382

G

eukaryotic translation elongation factor 1 delta

increases expression

alpha-Chlorohydrin results in increased expression of EEF1D protein

NCBI chr15:75,766,643...75,781,425
Ensembl chr15:75,766,054...75,781,405

G

eukaryotic translation elongation factor 1 epsilon 1

increases expression

alpha-Chlorohydrin results in increased expression of EEF1E1 protein

NCBI chr13:38,829,667...38,843,004
Ensembl chr13:38,828,183...38,843,034

G

eukaryotic translation elongation factor 1 gamma

decreases expression
increases expression

alpha-Chlorohydrin analog results in decreased expression of EEF1G protein; alpha-Chlorohydrin results in decreased expression of EEF1G protein
alpha-Chlorohydrin results in increased expression of EEF1G protein

PMID:26072098 PMID:34915118

NCBI chr19:8,944,405...8,955,544
Ensembl chr19:8,944,405...8,955,843

G

eukaryotic translation elongation factor 2

increases expression
decreases expression

alpha-Chlorohydrin results in increased expression of EEF2 protein
alpha-Chlorohydrin analog results in decreased expression of EEF2 protein

PMID:26072098 PMID:26597043

NCBI chr10:81,012,465...81,018,343
Ensembl chr10:81,012,465...81,018,332

G

eukaryotic elongation factor, selenocysteine-tRNA-specific

increases expression

alpha-Chlorohydrin results in increased expression of EEFSEC protein

NCBI chr 6:88,234,318...88,423,489
Ensembl chr 6:88,234,316...88,423,521

G

EF-hand calcium binding domain 5

increases expression

alpha-Chlorohydrin results in increased expression of EFCAB5 mRNA

NCBI chr11:76,980,236...77,106,926
Ensembl chr11:76,980,741...77,079,794

G

epidermal growth factor

multiple interactions

[alpha-Chlorohydrin co-treated with glycidol] results in decreased expression of EGF mRNA

NCBI chr 3:129,471,223...129,548,971
Ensembl chr 3:129,471,214...129,548,965

G

epidermal growth factor receptor

increases expression

alpha-Chlorohydrin results in increased expression of EGFR mRNA

NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158

G

early growth response 1

increases expression
decreases expression

alpha-Chlorohydrin results in increased expression of EGR1 mRNA
alpha-Chlorohydrin results in decreased expression of EGR1 mRNA

PMID:14644096 PMID:28522335

NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037

G

EH domain binding protein 1

increases expression

alpha-Chlorohydrin results in increased expression of EHBP1 protein

NCBI chr11:21,955,825...22,237,086
Ensembl chr11:21,955,828...22,292,292

G

EH domain binding protein 1-like 1

increases expression

alpha-Chlorohydrin results in increased expression of EHBP1L1 protein

NCBI chr19:5,757,397...5,776,504
Ensembl chr19:5,757,404...5,776,345

G

EH-domain containing 4

decreases expression

alpha-Chlorohydrin results in decreased expression of EHD4 mRNA

NCBI chr 2:119,919,958...119,985,028
Ensembl chr 2:119,919,656...119,985,087

G

eukaryotic translation initiation factor 2A

increases expression

alpha-Chlorohydrin results in increased expression of EIF2A protein

NCBI chr 3:58,433,252...58,464,922
Ensembl chr 3:58,433,242...58,464,922

G

eukaryotic translation initiation factor 2-alpha kinase 2

increases expression

alpha-Chlorohydrin results in increased expression of EIF2AK2 protein

NCBI chr17:79,157,933...79,190,001
Ensembl chr17:79,159,993...79,190,002

G

eukaryotic translation initiation factor 2 alpha kinase 3

multiple interactions

4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of and results in increased phosphorylation of EIF2AK3 protein]; alpha-Chlorohydrin results in increased expression of and results in increased phosphorylation of EIF2AK3 protein

NCBI chr 6:70,821,468...70,882,225
Ensembl chr 6:70,821,499...70,882,229

G

eukaryotic translation initiation factor 2B, subunit 2 beta

increases expression

alpha-Chlorohydrin results in increased expression of EIF2B2 protein

NCBI chr12:85,266,255...85,273,402
Ensembl chr12:85,266,255...85,273,402

G

eukaryotic translation initiation factor 2B, subunit 3

increases expression

alpha-Chlorohydrin results in increased expression of EIF2B3 protein

NCBI chr 4:116,876,559...116,944,049
Ensembl chr 4:116,876,599...116,944,503

G

eukaryotic translation initiation factor 2B, subunit 4 delta

increases expression

alpha-Chlorohydrin results in increased expression of EIF2B4 protein

NCBI chr 5:31,344,902...31,350,483
Ensembl chr 5:31,344,902...31,350,774

G

eukaryotic translation initiation factor 2, subunit 1 alpha

multiple interactions
increases phosphorylation

4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of and results in increased phosphorylation of EIF2S1 protein]; alpha-Chlorohydrin results in increased expression of and results in increased phosphorylation of EIF2S1 protein
alpha-Chlorohydrin results in increased phosphorylation of EIF2S1 protein

NCBI chr12:78,908,846...78,933,784
Ensembl chr12:78,908,593...78,933,784

G

eukaryotic translation initiation factor 2 subunit 2 beta

increases expression

alpha-Chlorohydrin results in increased expression of EIF2S2 protein

NCBI chr 2:154,713,330...154,734,826
Ensembl chr 2:154,713,330...154,734,855

G

eukaryotic translation initiation factor 3, subunit G

increases expression

alpha-Chlorohydrin results in increased expression of EIF3G protein

NCBI chr 9:20,805,645...20,809,886
Ensembl chr 9:20,805,645...20,809,919

G

eukaryotic translation initiation factor 3, subunit I

decreases expression

alpha-Chlorohydrin analog results in decreased expression of EIF3I protein; alpha-Chlorohydrin results in decreased expression of EIF3I protein

NCBI chr 4:129,485,767...129,494,441
Ensembl chr 4:129,485,753...129,494,441

G

eukaryotic translation initiation factor 4B

increases expression

alpha-Chlorohydrin results in increased expression of EIF4B protein

NCBI chr15:101,982,208...102,005,608
Ensembl chr15:101,982,208...102,005,608

G

eukaryotic translation initiation factor 4E binding protein 1

multiple interactions
decreases phosphorylation

3-methyladenine inhibits the reaction [Diosgenin promotes the reaction [alpha-Chlorohydrin results in decreased phosphorylation of EIF4EBP1 protein]]; Diosgenin promotes the reaction [alpha-Chlorohydrin results in decreased phosphorylation of EIF4EBP1 protein]

NCBI chr 8:27,750,355...27,765,684
Ensembl chr 8:27,750,357...27,766,702

G

eukaryotic translation initiation factor 6

increases expression

alpha-Chlorohydrin results in increased expression of EIF6 protein

NCBI chr 2:155,661,757...155,668,845
Ensembl chr 2:155,661,752...155,668,845

G

ELOVL fatty acid elongase 2

increases expression

alpha-Chlorohydrin results in increased expression of ELOVL2 mRNA

NCBI chr13:41,335,858...41,373,879
Ensembl chr13:41,335,857...41,373,881

G

ELOVL fatty acid elongase 6

increases expression

alpha-Chlorohydrin results in increased expression of ELOVL6 mRNA

NCBI chr 3:129,326,035...129,432,144
Ensembl chr 3:129,326,004...129,432,144

G

embigin

decreases expression

alpha-Chlorohydrin results in decreased expression of EMB mRNA

NCBI chr13:117,357,109...117,410,951
Ensembl chr13:117,345,072...117,410,951

G

ER membrane protein complex subunit 2

increases expression

alpha-Chlorohydrin results in increased expression of TTC35 protein

NCBI chr15:43,340,603...43,391,174
Ensembl chr15:43,340,625...43,391,159

G

ER membrane protein complex subunit 7

increases expression

alpha-Chlorohydrin results in increased expression of EMC7 protein

NCBI chr 2:112,285,332...112,302,507
Ensembl chr 2:112,285,342...112,302,507

G

endomucin

decreases expression

alpha-Chlorohydrin results in decreased expression of EMCN mRNA

NCBI chr 3:137,046,824...137,136,830
Ensembl chr 3:137,046,828...137,137,946

G

EMG1 N1-specific pseudouridine methyltransferase

increases expression

alpha-Chlorohydrin results in increased expression of EMG1 protein

NCBI chr 6:124,681,344...124,689,118
Ensembl chr 6:124,681,048...124,689,141

G

endonuclease G

increases expression

alpha-Chlorohydrin results in increased expression of ENDOG protein

NCBI chr 2:30,061,525...30,064,057
Ensembl chr 2:30,061,505...30,064,081

G

endoglin

increases expression

alpha-Chlorohydrin results in increased expression of ENG protein

NCBI chr 2:32,536,607...32,572,681
Ensembl chr 2:32,536,607...32,572,681

G

enolase 1, alpha non-neuron

affects expression
decreases expression

alpha-Chlorohydrin analog affects the expression of ENO1 protein
alpha-Chlorohydrin results in decreased expression of ENO1 protein

NCBI chr 4:150,321,165...150,333,336
Ensembl chr 4:150,321,178...150,333,336
Ensembl chr18:150,321,178...150,333,336

G

ecto-NOX disulfide-thiol exchanger 1

decreases expression

alpha-Chlorohydrin results in decreased expression of ENOX1 mRNA

NCBI chr14:77,393,790...77,959,203
Ensembl chr14:77,394,203...77,959,200

G

ectonucleotide pyrophosphatase/phosphodiesterase 1

decreases expression

alpha-Chlorohydrin results in decreased expression of ENPP1 protein

NCBI chr10:24,513,812...24,588,057
Ensembl chr10:24,513,812...24,588,057

G

ectonucleotide pyrophosphatase/phosphodiesterase 2

increases expression

alpha-Chlorohydrin results in increased expression of ENPP2 mRNA

NCBI chr15:54,702,297...54,816,284
Ensembl chr15:54,702,297...54,816,288

G

ectonucleoside triphosphate diphosphohydrolase 2

increases expression

alpha-Chlorohydrin results in increased expression of ENTPD2 protein

NCBI chr 2:25,285,886...25,291,335
Ensembl chr 2:25,285,886...25,291,333

G

erythrocyte membrane protein band 4.1 like 3

increases expression

alpha-Chlorohydrin results in increased expression of EPB41L3 mRNA

NCBI chr17:69,382,642...69,596,986
Ensembl chr17:69,382,678...69,596,984

G

epoxide hydrolase 1, microsomal

increases expression

alpha-Chlorohydrin results in increased expression of EPHX1 mRNA; alpha-Chlorohydrin results in increased expression of EPHX1 protein

PMID:28522335 PMID:34915118

NCBI chr 1:180,817,121...180,845,134
Ensembl chr 1:180,803,775...180,848,469

G

glutamyl-prolyl-tRNA synthetase 1

increases expression

alpha-Chlorohydrin results in increased expression of EPRS1 protein

NCBI chr 1:185,093,614...185,160,557
Ensembl chr 1:185,095,241...185,160,557

G

epidermal growth factor receptor pathway substrate 15

increases expression

alpha-Chlorohydrin results in increased expression of EPS15 protein

NCBI chr 4:109,137,372...109,245,014
Ensembl chr 4:109,137,465...109,245,014

G

epidermal growth factor receptor pathway substrate 8

increases expression

alpha-Chlorohydrin results in increased expression of EPS8 mRNA

NCBI chr 6:137,454,242...137,626,262
Ensembl chr 6:137,454,243...137,631,874

G

Era like 12S mitochondrial rRNA chaperone 1

increases expression

alpha-Chlorohydrin results in increased expression of ERAL1 protein

NCBI chr11:77,964,202...77,971,209
Ensembl chr11:77,964,202...77,971,209

G

endoplasmic reticulum aminopeptidase 1

increases expression

alpha-Chlorohydrin results in increased expression of ERAP1 protein

NCBI chr13:74,787,692...74,841,321
Ensembl chr13:74,787,687...74,841,320

G

erb-b2 receptor tyrosine kinase 4

decreases expression

alpha-Chlorohydrin results in decreased expression of ERBB4 mRNA

NCBI chr 1:68,071,063...69,147,756
Ensembl chr 1:68,071,345...69,147,218

G

endoplasmic reticulum lectin 1

increases expression

alpha-Chlorohydrin results in increased expression of ERLEC1 protein

NCBI chr11:30,812,794...30,904,385
Ensembl chr11:30,880,774...30,904,335

G

endoplasmic reticulum to nucleus signalling 1

increases expression
multiple interactions

alpha-Chlorohydrin results in increased expression of ERN1 mRNA
4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of and results in increased phosphorylation of ERN1 protein]; alpha-Chlorohydrin results in increased expression of and results in increased phosphorylation of ERN1 protein

PMID:28522335 PMID:33651226

NCBI chr11:106,285,474...106,378,701
Ensembl chr11:106,285,476...106,378,678

G

endoplasmic reticulum oxidoreductase 1 alpha

decreases expression

alpha-Chlorohydrin results in decreased expression of ERO1A protein

NCBI chr14:45,520,544...45,556,029
Ensembl chr14:45,520,544...45,556,228

G

endoplasmic reticulum oxidoreductase 1 beta

increases expression

alpha-Chlorohydrin results in increased expression of ERO1B protein

NCBI chr13:12,580,701...12,624,422
Ensembl chr13:12,580,755...12,626,285

G

ERBB receptor feedback inhibitor 1

increases expression

alpha-Chlorohydrin results in increased expression of ERRFI1 mRNA

NCBI chr 4:150,938,253...150,953,346
Ensembl chr 4:150,938,376...150,953,349

G

endothelial cell-specific molecule 1

decreases expression

alpha-Chlorohydrin results in decreased expression of ESM1 mRNA

NCBI chr13:113,346,193...113,354,638
Ensembl chr13:113,346,193...113,354,632

G

extra spindle pole bodies 1, separase

increases expression

alpha-Chlorohydrin results in increased expression of ESPL1 mRNA

NCBI chr15:102,204,688...102,232,792
Ensembl chr15:102,204,701...102,232,792

G

ethylmalonic encephalopathy 1

increases expression

alpha-Chlorohydrin results in increased expression of ETHE1 mRNA

NCBI chr 7:24,286,968...24,308,350
Ensembl chr 7:24,286,968...24,308,350

G

ecotropic viral integration site 2

affects expression

alpha-Chlorohydrin affects the expression of EVI2B mRNA

NCBI chr11:79,404,211...79,421,435
Ensembl chr11:79,405,882...79,414,588
Ensembl chr11:79,405,882...79,414,588

G

exonuclease 3'-5' domain containing 2

increases expression

alpha-Chlorohydrin results in increased expression of EXD2 protein

NCBI chr12:80,509,869...80,544,909
Ensembl chr12:80,509,869...80,547,001

G

exocyst complex component 3

increases expression

alpha-Chlorohydrin results in increased expression of EXOC3 protein

NCBI chr13:74,317,921...74,358,151
Ensembl chr13:74,317,607...74,356,851

G

exosome component 7

increases expression

alpha-Chlorohydrin results in increased expression of EXOSC7 protein

NCBI chr 9:122,942,310...122,965,194
Ensembl chr 9:122,942,280...122,965,194

G

coagulation factor XIII, beta subunit

increases expression

alpha-Chlorohydrin results in increased expression of F13B mRNA

NCBI chr 1:139,429,285...139,451,496
Ensembl chr 1:139,429,440...139,451,490

G

coagulation factor II thrombin receptor

decreases expression

alpha-Chlorohydrin results in decreased expression of F2R mRNA

NCBI chr13:95,738,288...95,754,974
Ensembl chr13:95,738,311...95,754,995

G

fatty acid binding protein 4, adipocyte

decreases expression

alpha-Chlorohydrin results in decreased expression of FABP4 mRNA

NCBI chr 3:10,269,406...10,273,653
Ensembl chr 3:10,269,148...10,273,636

G

fatty acid desaturase 3

increases expression

alpha-Chlorohydrin results in increased expression of FADS3 protein

NCBI chr19:10,018,189...10,037,477
Ensembl chr19:10,018,933...10,037,474

G

Fas associated factor family member 2

increases expression

alpha-Chlorohydrin results in increased expression of FAF2 protein

NCBI chr13:54,769,597...54,811,876
Ensembl chr13:54,769,597...54,811,876

G

fumarylacetoacetate hydrolase domain containing 1

decreases expression

alpha-Chlorohydrin analog results in decreased expression of FAHD1 protein

NCBI chr17:25,067,866...25,069,276
Ensembl chr17:25,067,866...25,069,338

G

family with sequence similarity 136, member A

increases expression

alpha-Chlorohydrin results in increased expression of FAM136A protein

NCBI chr 6:86,342,453...86,347,040
Ensembl chr 6:86,342,628...86,347,040

G

family with sequence simliarity 151, member A

increases expression

alpha-Chlorohydrin results in increased expression of FAM151A mRNA

NCBI chr 4:106,591,112...106,605,489
Ensembl chr 4:106,591,086...106,605,489

G

family with sequence similarity 169, member A

increases expression

alpha-Chlorohydrin results in increased expression of FAM169A mRNA

NCBI chr13:97,203,795...97,266,801
Ensembl chr13:97,203,794...97,267,521

G

family with sequence similarity 170, member B

decreases expression

alpha-Chlorohydrin results in decreased expression of FAM170B mRNA

NCBI chr14:32,555,938...32,558,746
Ensembl chr14:32,555,919...32,558,746

G

family with sequence similarity 229, member A

decreases expression

alpha-Chlorohydrin results in decreased expression of FAM229A mRNA

NCBI chr 4:129,384,983...129,385,749
Ensembl chr 4:129,384,983...129,385,749

G

family with sequence similarity 43, member A

decreases expression

alpha-Chlorohydrin results in decreased expression of FAM43A mRNA

NCBI chr16:30,418,541...30,421,615
Ensembl chr16:30,418,541...30,421,615

G

family with sequence similarity 78, member A

decreases expression

alpha-Chlorohydrin results in decreased expression of FAM78A mRNA

NCBI chr 2:31,932,720...31,977,484
Ensembl chr 2:31,940,098...31,954,923
Ensembl chr 2:31,940,098...31,954,923

G

family with sequence similarity 83, member B

decreases expression

alpha-Chlorohydrin results in decreased expression of FAM83B mRNA

NCBI chr 9:76,394,742...76,474,397
Ensembl chr 9:76,397,336...76,474,398

G

family with sequence similarity 83, member G

increases expression

alpha-Chlorohydrin results in increased expression of FAM83G mRNA

NCBI chr11:61,574,908...61,600,776
Ensembl chr11:61,574,917...61,600,777

G

family with sequence similarity 98, member A

increases expression

alpha-Chlorohydrin results in increased expression of FAM98A protein

NCBI chr17:75,844,080...75,858,941
Ensembl chr17:75,844,081...75,858,941

G

Fanconi anemia, complementation group A

increases expression

alpha-Chlorohydrin results in increased expression of FANCA mRNA

NCBI chr 8:123,993,033...124,045,390
Ensembl chr 8:123,995,039...124,045,315

G

Fanconi anemia, complementation group B

increases expression

alpha-Chlorohydrin results in increased expression of FANCB mRNA

NCBI chr X:163,763,678...163,780,266
Ensembl chr X:163,763,588...163,780,268

G

FERM, ARH/RhoGEF and pleckstrin domain protein 1

increases expression

alpha-Chlorohydrin results in increased expression of FARP1 protein

NCBI chr14:121,272,563...121,521,156
Ensembl chr14:121,272,612...121,521,156

G

phenylalanine-tRNA synthetase 2, mitochondrial

increases expression

alpha-Chlorohydrin results in increased expression of FARS2 protein

NCBI chr13:36,301,373...36,721,569
Ensembl chr13:36,301,395...36,910,254

G

Fas cell surface death receptor

increases expression

alpha-Chlorohydrin results in increased expression of FAS mRNA

NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172

G

Fas ligand

increases expression

alpha-Chlorohydrin results in increased expression of FASLG mRNA

NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064

G

FAST kinase domains 2

increases expression

alpha-Chlorohydrin results in increased expression of FASTKD2 protein

NCBI chr 1:63,769,758...63,792,544
Ensembl chr 1:63,769,773...63,793,814

G

FAST kinase domains 5

increases expression

alpha-Chlorohydrin results in increased expression of FASTKD5 mRNA

NCBI chr 2:130,455,766...130,471,922
Ensembl chr 2:130,455,760...130,471,947

G

FAU ubiquitin like and ribosomal protein S30 fusion

decreases expression

alpha-Chlorohydrin results in decreased expression of FAU mRNA

NCBI chr19:6,107,977...6,109,554
Ensembl chr19:6,107,874...6,109,554

G

fibrillarin

increases expression

alpha-Chlorohydrin results in increased expression of FBL protein

NCBI chr 7:27,868,293...27,878,701
Ensembl chr 7:27,869,135...27,878,694

G

fibrillin 1

increases expression

alpha-Chlorohydrin results in increased expression of FBN1 mRNA; alpha-Chlorohydrin results in increased expression of FBN1 protein

PMID:28522335 PMID:34915118

NCBI chr 2:125,142,514...125,348,417
Ensembl chr 2:125,142,514...125,349,913

G

fructose bisphosphatase 2

increases expression

alpha-Chlorohydrin results in increased expression of FBP2 protein

NCBI chr13:62,984,698...63,006,214
Ensembl chr13:62,984,691...63,006,236

G

F-box protein 32

increases expression

alpha-Chlorohydrin results in increased expression of FBXO32 mRNA

NCBI chr15:58,039,275...58,078,288
Ensembl chr15:58,039,275...58,078,328

G

F-box protein 4

increases expression

alpha-Chlorohydrin results in increased expression of FBXO4 protein

NCBI chr15:3,993,046...4,009,055
Ensembl chr15:3,994,927...4,009,055

G

Fc receptor, IgG, low affinity III

decreases expression

alpha-Chlorohydrin results in decreased expression of FCGR2A mRNA

NCBI chr 1:170,878,738...170,893,477
Ensembl chr 1:170,878,743...170,892,504

G

FCH and double SH3 domains 1

increases expression

alpha-Chlorohydrin results in increased expression of FCHSD1 protein

NCBI chr18:38,090,484...38,102,828
Ensembl chr18:38,090,484...38,102,827

G

farnesyl diphosphate synthetase

increases expression

alpha-Chlorohydrin analog results in increased expression of FDPS protein; alpha-Chlorohydrin results in increased expression of FDPS protein

NCBI chr 3:89,000,895...89,009,274
Ensembl chr 3:89,000,895...89,009,266

G

ferredoxin reductase

decreases expression

alpha-Chlorohydrin results in decreased expression of FDXR protein

NCBI chr11:115,158,850...115,167,925
Ensembl chr11:115,158,850...115,167,876

G

ferrochelatase

increases expression

alpha-Chlorohydrin results in increased expression of FECH protein

NCBI chr18:64,589,613...64,622,169
Ensembl chr18:64,585,985...64,623,322

G

flap structure specific endonuclease 1

increases expression

alpha-Chlorohydrin results in increased expression of FEN1 protein

NCBI chr19:10,176,496...10,181,757
Ensembl chr19:10,176,496...10,181,533

G

FGGY carbohydrate kinase domain containing

decreases expression

alpha-Chlorohydrin results in decreased expression of FGGY protein

NCBI chr 4:95,445,717...95,815,176
Ensembl chr 4:95,445,744...95,815,176

G

FHF complex subunit HOOK interacting protein 1B

increases expression

alpha-Chlorohydrin results in increased expression of FHIP1B protein

NCBI chr 7:105,020,418...105,049,349
Ensembl chr 7:105,020,418...105,049,261

G

fragile histidine triad gene

decreases expression

alpha-Chlorohydrin results in decreased expression of FHIT mRNA

NCBI chr14:11,307,718...12,919,681
Ensembl chr14:11,307,738...12,919,681

G

fibroblast growth factor (acidic) intracellular binding protein

increases expression

alpha-Chlorohydrin results in increased expression of FIBP protein

NCBI chr19:5,510,626...5,515,080
Ensembl chr19:5,510,643...5,515,079

G

fission, mitochondrial 1

multiple interactions
increases expression

4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of FIS1 protein]; Diosgenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of FIS1 protein]

PMID:33651226 PMID:35149085

NCBI chr 5:136,982,129...136,995,088
Ensembl chr 5:136,982,129...136,995,088

G

FK506 binding protein 10

increases expression

alpha-Chlorohydrin results in increased expression of FKBP10 protein

NCBI chr11:100,306,520...100,315,666
Ensembl chr11:100,306,523...100,315,650

G

FK506 binding protein 11

increases expression

alpha-Chlorohydrin results in increased expression of FKBP11 protein

NCBI chr15:98,622,249...98,626,079
Ensembl chr15:98,622,247...98,626,079

G

FK506 binding protein 9

increases expression

alpha-Chlorohydrin results in increased expression of FKBP9 mRNA

NCBI chr 6:56,809,044...56,856,345
Ensembl chr 6:56,809,044...56,856,343

G

flightless I actin binding protein

increases expression

alpha-Chlorohydrin results in increased expression of FLII protein

NCBI chr11:60,604,969...60,618,089
Ensembl chr11:60,604,949...60,618,089

G

filamin, beta

increases expression

alpha-Chlorohydrin results in increased expression of FLNB protein

NCBI chr14:14,518,185...14,651,852
Ensembl chr14:14,518,185...14,651,816

G

formation of mitochondrial complex V assembly factor 1

increases expression

alpha-Chlorohydrin results in increased expression of FMC1 protein

NCBI chr 6:38,511,796...38,516,384
Ensembl chr 6:38,510,437...38,516,384

G

flavin containing monooxygenase 1

decreases expression

alpha-Chlorohydrin results in decreased expression of FMO1 protein

NCBI chr 1:162,657,130...162,694,170
Ensembl chr 1:162,657,130...162,694,179

G

flavin containing monooxygenase 3

increases expression

alpha-Chlorohydrin results in increased expression of FMO3 mRNA

NCBI chr 1:162,781,368...162,812,097
Ensembl chr 1:162,781,369...162,812,097

G

fructosamine 3 kinase

decreases expression

alpha-Chlorohydrin results in decreased expression of FN3K protein

NCBI chr11:121,325,779...121,341,316
Ensembl chr11:121,325,739...121,341,317

G

formin binding protein 1

increases expression

alpha-Chlorohydrin results in increased expression of FNBP1 protein

NCBI chr 2:30,916,218...31,032,046
Ensembl chr 2:30,916,218...31,032,020

G

folate hydrolase 1

decreases expression

alpha-Chlorohydrin results in decreased expression of FOLH1 protein

NCBI chr 7:86,365,733...86,425,171
Ensembl chr 7:86,368,185...86,425,151

G

folate receptor alpha

increases expression

alpha-Chlorohydrin results in increased expression of FOLR1 mRNA

NCBI chr 7:101,507,551...101,519,974
Ensembl chr 7:101,507,538...101,519,995

G

folate receptor beta

decreases expression

alpha-Chlorohydrin analog results in decreased expression of FOLR2 protein

NCBI chr 7:101,489,195...101,506,397
Ensembl chr 7:101,489,195...101,506,401

G

forkhead box A3

decreases expression

alpha-Chlorohydrin results in decreased expression of FOXA3 mRNA

NCBI chr 7:18,747,208...18,757,464
Ensembl chr 7:18,747,209...18,757,463

G

forkhead box C1

decreases expression

alpha-Chlorohydrin results in decreased expression of FOXC1 mRNA

NCBI chr13:31,990,629...31,994,618
Ensembl chr13:31,990,616...31,996,459

G

Fraser extracellular matrix complex subunit 1

decreases expression

alpha-Chlorohydrin results in decreased expression of FRAS1 mRNA

NCBI chr 5:96,518,622...96,932,592
Ensembl chr 5:96,521,814...96,932,587

G

Fras1 related extracellular matrix protein 2

decreases expression

alpha-Chlorohydrin results in decreased expression of FREM2 mRNA

NCBI chr 3:53,421,359...53,566,014
Ensembl chr 3:53,421,359...53,564,776

G

fyn-related kinase

increases expression

alpha-Chlorohydrin results in increased expression of FRK protein

NCBI chr10:34,359,396...34,487,530
Ensembl chr10:34,359,395...34,487,274

G

fibrous sheath-interacting protein 1

decreases expression

alpha-Chlorohydrin analog results in decreased expression of FSIP1 protein; alpha-Chlorohydrin results in decreased expression of FSIP1 protein

NCBI chr 2:117,960,742...118,087,468
Ensembl chr 2:117,960,905...118,087,447

G

formiminotransferase cyclodeaminase

decreases expression

alpha-Chlorohydrin analog results in decreased expression of FTCD protein; alpha-Chlorohydrin results in decreased expression of FTCD protein

NCBI chr10:76,411,482...76,426,172
Ensembl chr10:76,411,482...76,426,172

G

ferritin heavy polypeptide 1

decreases expression

alpha-Chlorohydrin analog results in decreased expression of FTH1 protein

NCBI chr19:9,957,964...9,962,475
Ensembl chr19:9,957,962...9,962,462

G

ferritin light polypeptide 1

decreases expression

alpha-Chlorohydrin results in decreased expression of FTL1 protein

NCBI chr 7:45,107,368...45,109,310
Ensembl chr 7:45,107,368...45,109,308

G

FtsJ RNA 2'-O-methyltransferase 3

increases expression

alpha-Chlorohydrin results in increased expression of FTSJ3 protein

NCBI chr11:106,139,964...106,146,910
Ensembl chr11:106,139,968...106,146,905

G

far upstream element (FUSE) binding protein 1

increases expression

alpha-Chlorohydrin results in increased expression of FUBP1 protein

NCBI chr 3:151,916,059...151,942,467
Ensembl chr 3:151,916,059...151,942,463

G

far upstream element (FUSE) binding protein 3

increases expression

alpha-Chlorohydrin results in increased expression of FUBP3 protein

NCBI chr 2:31,462,655...31,507,538
Ensembl chr 2:31,462,663...31,507,538

G

fucosidase, alpha-L- 1, tissue

increases expression

alpha-Chlorohydrin results in increased expression of FUCA1 mRNA

NCBI chr 4:135,648,037...135,667,611
Ensembl chr 4:135,648,046...135,667,622

G

fucose mutarotase

decreases expression

alpha-Chlorohydrin results in decreased expression of FUOM protein

NCBI chr 7:139,677,724...139,684,745
Ensembl chr 7:139,676,683...139,682,354

G

fucosyltransferase 8

decreases expression

alpha-Chlorohydrin results in decreased expression of FUT8 mRNA

NCBI chr12:77,284,878...77,522,770
Ensembl chr12:77,284,899...77,523,112

G

glucose-6-phosphate dehydrogenase X-linked

increases expression

alpha-Chlorohydrin results in increased expression of G6PD protein

NCBI chr X:73,453,089...73,472,486
Ensembl chr X:73,453,089...73,472,800

G

gamma-aminobutyric acid type B receptor subunit 2

increases expression

alpha-Chlorohydrin results in increased expression of GABBR2 mRNA

NCBI chr 4:46,662,318...46,991,714
Ensembl chr 4:46,662,305...46,991,873

G

GABRB3, gamma-aminobutyric acid type A receptor subunit beta 3

increases expression

alpha-Chlorohydrin results in increased expression of GABRB3 mRNA

NCBI chr 7:57,240,266...57,478,550
Ensembl chr 7:57,069,440...57,478,550

G

gamma-aminobutyric acid type A receptor subunit gamma 1

increases expression

alpha-Chlorohydrin results in increased expression of GABRG1 mRNA

NCBI chr 5:70,906,512...70,999,960
Ensembl chr 5:70,908,390...70,999,960

G

growth arrest and DNA-damage-inducible 45 alpha

increases expression

alpha-Chlorohydrin results in increased expression of GADD45A mRNA

NCBI chr 6:67,012,080...67,014,391
Ensembl chr 6:67,012,080...67,014,441

G

galactokinase 1

increases expression

alpha-Chlorohydrin results in increased expression of GALK1 protein

NCBI chr11:115,899,183...115,903,545
Ensembl chr11:115,899,283...115,903,545

G

galactose mutarotase

decreases expression

alpha-Chlorohydrin results in decreased expression of GALM protein

NCBI chr17:80,434,886...80,492,461
Ensembl chr17:80,434,900...80,492,530

G

guanidinoacetate methyltransferase

multiple interactions
decreases expression

[alpha-Chlorohydrin co-treated with glycidol] results in decreased expression of GAMT mRNA
alpha-Chlorohydrin results in decreased expression of GAMT protein

PMID:33187795 PMID:34915118

NCBI chr10:80,093,985...80,096,846
Ensembl chr10:80,093,985...80,096,846

G

glyceraldehyde-3-phosphate dehydrogenase

multiple interactions
decreases expression
decreases activity

[alpha-Chlorohydrin results in decreased activity of GAPDH protein] which results in decreased reduction of Arsenates
alpha-Chlorohydrin analog results in decreased expression of GAPDH protein; alpha-Chlorohydrin results in decreased expression of GAPDH protein

PMID:16322075 PMID:26597043

NCBI chr 6:125,138,812...125,143,450
Ensembl chr 6:125,138,678...125,143,430

G

glyceraldehyde-3-phosphate dehydrogenase, spermatogenic

decreases expression

alpha-Chlorohydrin results in decreased expression of GAPDHS mRNA

NCBI chr 7:30,429,204...30,443,106
Ensembl chr 7:30,429,200...30,443,106

G

GTPase activating RANGAP domain-like 3

increases expression

alpha-Chlorohydrin results in increased expression of GARNL3 mRNA

NCBI chr 2:32,876,237...33,021,871
Ensembl chr 2:32,876,236...33,021,666

G

glycyl-tRNA synthetase 1

increases expression

alpha-Chlorohydrin results in increased expression of GARS1 protein

NCBI chr 6:55,014,986...55,056,489
Ensembl chr 6:55,014,992...55,056,485

G

growth arrest specific 5

decreases expression

alpha-Chlorohydrin results in decreased expression of GAS5 mRNA

NCBI chr 1:160,862,171...160,866,109
Ensembl chr 1:160,861,793...160,866,118

G

golgi associated kinase 1B

increases expression

alpha-Chlorohydrin results in increased expression of GASK1B mRNA

NCBI chr 3:79,791,795...79,853,585
Ensembl chr 3:79,791,840...79,853,587

G

1,4-alpha-glucan branching enzyme 1

increases expression

alpha-Chlorohydrin results in increased expression of GBE1 protein

NCBI chr16:70,110,837...70,366,608
Ensembl chr16:70,110,837...70,366,604

G

GTP cyclohydrolase I feedback regulator

decreases expression

alpha-Chlorohydrin results in decreased expression of GCHFR protein

NCBI chr 2:118,998,269...119,002,870
Ensembl chr 2:118,998,254...119,002,871

G

glucokinase

increases expression

alpha-Chlorohydrin results in increased expression of GCK mRNA

NCBI chr11:5,850,816...5,900,081
Ensembl chr11:5,850,820...5,900,081

G

glucokinase regulatory protein

increases expression

alpha-Chlorohydrin results in increased expression of GCKR protein

NCBI chr 5:31,454,594...31,484,646
Ensembl chr 5:31,454,787...31,484,658

G

glutamate-cysteine ligase, catalytic subunit

decreases expression

alpha-Chlorohydrin results in decreased expression of GCLC mRNA

NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767

G

GCN1 activator of EIF2AK4

increases expression

alpha-Chlorohydrin results in increased expression of GCN1 protein

NCBI chr 5:115,703,177...115,760,713
Ensembl chr 5:115,703,313...115,760,713

G

guanine deaminase

increases expression

alpha-Chlorohydrin results in increased expression of GDA mRNA; alpha-Chlorohydrin results in increased expression of GDA protein

PMID:28522335 PMID:34915118

NCBI chr19:21,368,671...21,450,025
Ensembl chr19:21,368,671...21,450,809

G

glycerophosphodiester phosphodiesterase domain containing 1

increases expression

alpha-Chlorohydrin results in increased expression of GDPD1 protein

NCBI chr11:86,924,620...86,964,963
Ensembl chr11:86,924,693...86,964,888

G

gem nuclear organelle associated protein 4

increases expression

alpha-Chlorohydrin results in increased expression of GEMIN4 protein

NCBI chr11:76,101,397...76,108,398
Ensembl chr11:76,101,397...76,108,490

G

gem nuclear organelle associated protein 5

increases expression

alpha-Chlorohydrin results in increased expression of GEMIN5 protein

NCBI chr11:58,010,827...58,059,378
Ensembl chr11:58,010,828...58,059,365

G

glutamine fructose-6-phosphate transaminase 1

increases expression

alpha-Chlorohydrin results in increased expression of GFPT1 protein

NCBI chr 6:87,019,828...87,069,189
Ensembl chr 6:87,019,828...87,069,179

G

golgi associated, gamma adaptin ear containing, ARF binding protein 2

increases expression

alpha-Chlorohydrin results in increased expression of GGA2 protein

NCBI chr 7:121,585,945...121,620,421
Ensembl chr 7:121,585,945...121,620,445

G

gamma-glutamyl cyclotransferase

decreases expression

alpha-Chlorohydrin results in decreased expression of GGCT mRNA

NCBI chr 6:54,962,080...54,969,947
Ensembl chr 6:54,959,565...54,969,935

G

gametogenetin binding protein 1

decreases expression

alpha-Chlorohydrin analog results in decreased expression of GGNBP1 protein

NCBI chr17:27,237,009...27,255,352
Ensembl chr17:27,236,961...27,256,598

G

gamma-glutamyltransferase 5

increases expression

alpha-Chlorohydrin results in increased expression of GGT5 protein

NCBI chr10:75,425,161...75,453,034
Ensembl chr10:75,425,174...75,453,034

G

growth hormone inducible transmembrane protein

increases expression

alpha-Chlorohydrin results in increased expression of GHITM protein

NCBI chr14:36,842,401...36,857,279
Ensembl chr14:36,842,049...36,857,229

G

growth hormone receptor

increases expression

alpha-Chlorohydrin results in increased expression of GHR mRNA

NCBI chr15:3,347,237...3,612,834
Ensembl chr15:3,347,242...3,612,974

G

GTPase, IMAP family member 8

decreases expression

alpha-Chlorohydrin analog results in decreased expression of GIMAP8 protein; alpha-Chlorohydrin results in decreased expression of GIMAP8 protein

NCBI chr 6:48,624,120...48,637,809
Ensembl chr 6:48,624,168...48,637,809

G

GIPC PDZ domain containing family, member 1

increases expression

alpha-Chlorohydrin results in increased expression of GIPC1 protein

NCBI chr 8:84,376,037...84,391,418
Ensembl chr 8:84,379,306...84,391,323

G

galactosidase, beta 1

increases expression

alpha-Chlorohydrin results in increased expression of GLB1 protein

NCBI chr 9:114,230,146...114,303,447
Ensembl chr 9:114,230,144...114,303,966

G

galactosidase, beta 1-like

increases expression

alpha-Chlorohydrin results in increased expression of GLB1L protein

NCBI chr 1:75,174,178...75,187,460
Ensembl chr 1:75,174,880...75,187,457

G

glycine decarboxylase

decreases expression

alpha-Chlorohydrin results in decreased expression of GLDC protein

NCBI chr19:30,075,847...30,152,829
Ensembl chr19:30,075,847...30,152,829

G

glomulin, FKBP associated protein

increases expression

alpha-Chlorohydrin results in increased expression of GLMN protein

NCBI chr 5:107,696,828...107,745,754
Ensembl chr 5:107,696,833...107,745,754

G

glycosylated lysosomal membrane protein

increases expression

alpha-Chlorohydrin results in increased expression of GLMP mRNA

NCBI chr 3:88,232,330...88,235,938
Ensembl chr 3:88,232,330...88,238,620

G

glyoxalase 1

decreases expression

alpha-Chlorohydrin results in decreased expression of GLO1 protein

NCBI chr17:30,811,835...30,831,633
Ensembl chr17:30,803,910...30,845,845

G

glyoxalase domain containing 4

increases expression

alpha-Chlorohydrin results in increased expression of GLOD4 mRNA

NCBI chr11:76,111,221...76,134,525
Ensembl chr11:76,011,813...76,134,551

G

glutaredoxin

increases expression

alpha-Chlorohydrin results in increased expression of GLRX mRNA

NCBI chr13:75,988,004...75,998,270
Ensembl chr13:75,987,987...75,998,273

G

glutaredoxin 3

increases expression

alpha-Chlorohydrin results in increased expression of GLRX3 protein

NCBI chr 7:137,039,302...137,071,360
Ensembl chr 7:137,039,343...137,070,323

G

glutaminase

increases expression

alpha-Chlorohydrin results in increased expression of GLS mRNA; alpha-Chlorohydrin results in increased expression of GLS protein

PMID:28522335 PMID:34915118

NCBI chr 1:52,202,608...52,274,168
Ensembl chr 1:52,202,607...52,272,391

G

glutaminase 2 (liver, mitochondrial)

increases expression

alpha-Chlorohydrin results in increased expression of GLS2 protein

NCBI chr10:128,030,504...128,045,873
Ensembl chr10:128,030,326...128,045,873

G

glutamate-ammonia ligase

affects expression

alpha-Chlorohydrin affects the expression of GLUL protein; alpha-Chlorohydrin analog affects the expression of GLUL protein

NCBI chr 1:153,775,692...153,785,469
Ensembl chr 1:153,775,690...153,785,469

G

glycine-N-acyltransferase

decreases expression

alpha-Chlorohydrin results in decreased expression of GLYAT protein

NCBI chr19:12,610,672...12,629,101
Ensembl chr19:12,610,672...12,631,275

G

Gem-interacting protein

increases expression

alpha-Chlorohydrin results in increased expression of GMIP protein

NCBI chr 8:70,260,912...70,274,520
Ensembl chr 8:70,261,329...70,274,520

G

guanine nucleotide binding protein, alpha O

increases expression

alpha-Chlorohydrin results in increased expression of GNAO1 mRNA

NCBI chr 8:94,537,213...94,696,016
Ensembl chr 8:94,536,594...94,696,016

G

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

increases expression

alpha-Chlorohydrin analog results in increased expression of GNE protein; alpha-Chlorohydrin results in increased expression of GNE protein

NCBI chr 4:44,034,075...44,084,177
Ensembl chr 4:44,034,075...44,084,177

G

guanine nucleotide binding protein (G protein), gamma 7

decreases expression

alpha-Chlorohydrin results in decreased expression of GNG7 protein

NCBI chr10:80,784,463...80,850,742
Ensembl chr10:80,784,458...80,850,779

G

glycine N-methyltransferase

decreases expression

alpha-Chlorohydrin results in decreased expression of GNMT protein
alpha-Chlorohydrin results in decreased expression of GNMT mRNA

PMID:26597043 PMID:35690182

NCBI chr17:47,036,590...47,040,091
Ensembl chr17:47,036,590...47,040,094

G

glucosamine-6-phosphate deaminase 1

increases expression

alpha-Chlorohydrin results in increased expression of GNPDA1 mRNA

NCBI chr18:38,460,588...38,472,052
Ensembl chr18:38,460,588...38,472,056

G

glucosamine-phosphate N-acetyltransferase 1

increases expression

alpha-Chlorohydrin results in increased expression of GNPNAT1 protein

NCBI chr14:45,613,897...45,626,972
Ensembl chr14:45,613,791...45,642,370

G

glucosamine (N-acetyl)-6-sulfatase

increases expression

alpha-Chlorohydrin results in increased expression of GNS mRNA

NCBI chr10:121,200,995...121,233,159
Ensembl chr10:121,200,995...121,233,154

G

golgin A2

increases expression

alpha-Chlorohydrin results in increased expression of GOLGA2 protein

NCBI chr 2:32,178,299...32,197,925
Ensembl chr 2:32,177,396...32,197,933

G

golgin A3

increases expression

alpha-Chlorohydrin results in increased expression of GOLGA3 protein

NCBI chr 5:110,324,723...110,374,336
Ensembl chr 5:110,324,567...110,374,336

G

golgin A4

increases expression

alpha-Chlorohydrin results in increased expression of GOLGA4 protein

NCBI chr 9:118,335,280...118,411,587
Ensembl chr 9:118,335,335...118,411,587

G

golgin B1

increases expression

alpha-Chlorohydrin results in increased expression of GOLGB1 protein

NCBI chr16:36,695,455...36,753,447
Ensembl chr16:36,695,502...36,753,447

G

glycoprotein 5 platelet

increases expression

alpha-Chlorohydrin results in increased expression of GP5 protein

NCBI chr16:30,126,503...30,129,599
Ensembl chr16:30,126,503...30,129,597

G

glycerol-3-phosphate dehydrogenase 1 (soluble)

decreases expression

alpha-Chlorohydrin analog results in decreased expression of GPD1 protein; alpha-Chlorohydrin results in decreased expression of GPD1 protein

NCBI chr15:99,615,468...99,622,895
Ensembl chr15:99,615,396...99,622,886

G

G protein-coupled receptor 31, D17Leh66b region

decreases expression

alpha-Chlorohydrin results in decreased expression of GPR31 mRNA

NCBI chr17:13,270,208...13,271,167
Ensembl chr17:13,269,901...13,271,183
Ensembl chr17:13,269,901...13,271,183

G

GPRIN family member 3

increases expression

alpha-Chlorohydrin results in increased expression of GPRIN3 mRNA

NCBI chr 6:59,317,988...59,403,291
Ensembl chr 6:59,324,211...59,403,279

G

glutamic pyruvic transaminase, soluble

increases expression

alpha-Chlorohydrin results in increased expression of GPT protein

NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886

G

glutathione peroxidase 1

increases expression
decreases expression

alpha-Chlorohydrin results in increased expression of GPX1 mRNA
alpha-Chlorohydrin results in decreased expression of GPX1 protein

PMID:28522335 PMID:34915118

NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542

G

growth factor receptor bound protein 10

increases expression

alpha-Chlorohydrin results in increased expression of GRB10 mRNA

NCBI chr11:11,880,499...11,987,428
Ensembl chr11:11,880,508...11,988,683

G

growth factor receptor bound protein 2

decreases expression

alpha-Chlorohydrin analog results in decreased expression of GRB2 protein

NCBI chr11:115,534,871...115,599,423
Ensembl chr11:115,534,871...115,599,423

G

gene regulated by estrogen in breast cancer protein

increases expression

alpha-Chlorohydrin results in increased expression of GREB1 mRNA

NCBI chr12:16,720,616...16,851,395
Ensembl chr12:16,720,616...16,850,887

G

glutamate receptor, ionotropic, kainate 3

decreases expression

alpha-Chlorohydrin results in decreased expression of GRIK3 mRNA

NCBI chr 4:125,384,025...125,607,966
Ensembl chr 4:125,384,493...125,607,966

G

glutamate receptor ionotropic, NMDA3A

decreases expression

alpha-Chlorohydrin analog results in decreased expression of GRIN3A protein

NCBI chr 4:49,661,611...49,846,023
Ensembl chr 4:49,661,611...49,845,744

G

GRIP1 associated protein 1

decreases expression

alpha-Chlorohydrin analog results in decreased expression of GRIPAP1 protein

NCBI chr X:7,656,009...7,686,805
Ensembl chr X:7,656,004...7,686,806

G

granulin

increases expression

alpha-Chlorohydrin results in increased expression of GRN mRNA

NCBI chr11:102,321,333...102,327,635
Ensembl chr11:102,321,141...102,327,874

G

GrpE-like 1, mitochondrial

decreases expression

alpha-Chlorohydrin analog results in decreased expression of GRPEL1 protein

NCBI chr 5:36,622,529...36,631,421
Ensembl chr 5:36,622,342...36,631,424

G

GH regulated TBC protein 1

decreases expression

alpha-Chlorohydrin results in decreased expression of GRTP1 protein

NCBI chr 8:13,226,869...13,250,695
Ensembl chr 8:13,222,022...13,250,620

G

gasdermin D

increases cleavage
multiple interactions

alpha-Chlorohydrin results in increased cleavage of GSDMD protein
ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in increased cleavage of GSDMD protein]
Cyclosporine inhibits the reaction [ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in increased cleavage of GSDMD protein]]; ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in increased cleavage of GSDMD protein]

PMID:33187795 PMID:38373586

NCBI chr15:75,733,990...75,739,257
Ensembl chr15:75,734,176...75,739,257

G

G1 to S phase transition 1

increases expression

alpha-Chlorohydrin results in increased expression of GSPT1 mRNA

NCBI chr16:11,034,104...11,072,189
Ensembl chr16:11,037,156...11,072,189

G

glutathione synthetase

increases expression
decreases expression

alpha-Chlorohydrin analog results in increased expression of GSS protein; alpha-Chlorohydrin results in increased expression of GSS protein
alpha-Chlorohydrin results in decreased expression of GSS protein

PMID:26072098 PMID:26597043

NCBI chr 2:155,405,101...155,434,730
Ensembl chr 2:155,405,101...155,434,730

G

glutathione S-transferase, alpha 1 (Ya)

decreases expression

alpha-Chlorohydrin analog results in decreased expression of GSTA5 protein

NCBI chr 9:78,137,951...78,149,965
Ensembl chr 9:78,137,938...78,149,966

G

glutathione S-transferase, alpha 2 (Yc2)

decreases expression

alpha-Chlorohydrin analog results in decreased expression of GSTA2 protein

NCBI chr 9:78,238,300...78,254,474
Ensembl chr 9:78,238,300...78,263,070

G

glutathione S-transferase, alpha 4

increases expression

alpha-Chlorohydrin results in increased expression of GSTA4 mRNA

NCBI chr 9:78,099,248...78,116,631
Ensembl chr 9:78,090,056...78,116,631

G

glutathione S-transferase, mu 1

increases expression

alpha-Chlorohydrin analog results in increased expression of GSTM1 protein

NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289

G

glutathione S-transferase, mu 2

increases expression

alpha-Chlorohydrin results in increased expression of GSTM2 protein

PMID:26072098 PMID:34915118

NCBI chr 3:107,889,018...107,893,736
Ensembl chr 3:107,889,018...107,893,769

G

glutathione S-transferase, mu 4

increases expression

alpha-Chlorohydrin results in increased expression of GSTM4 mRNA; alpha-Chlorohydrin results in increased expression of GSTM4 protein

PMID:28522335 PMID:34915118

NCBI chr 3:107,937,887...107,952,495
Ensembl chr 3:107,947,724...107,952,210

G

glutathione S-transferase, mu 5

decreases expression
increases expression

alpha-Chlorohydrin analog results in decreased expression of GSTM3 protein
alpha-Chlorohydrin results in increased expression of GSTM3 protein

PMID:26072098 PMID:26597043

NCBI chr 3:107,803,240...107,806,002
Ensembl chr 3:107,803,137...107,806,002

G

glutathione S-transferase, pi 1

increases expression

alpha-Chlorohydrin results in increased expression of GSTP1 mRNA; alpha-Chlorohydrin results in increased expression of GSTP1 protein

PMID:28522335 PMID:34915118

NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985

G

glutathione S-transferase, theta 1

increases expression

alpha-Chlorohydrin results in increased expression of GSTT1 mRNA

NCBI chr10:75,619,647...75,634,418
Ensembl chr10:75,619,647...75,634,418

G

general transcription factor IIF, polypeptide 2

increases expression

alpha-Chlorohydrin results in increased expression of GTF2F2 protein

NCBI chr14:76,134,368...76,248,356
Ensembl chr14:76,134,377...76,248,305

G

general transcription factor IIH, polypeptide 3

increases expression

alpha-Chlorohydrin results in increased expression of GTF2H3 protein

NCBI chr 5:124,717,211...124,735,743
Ensembl chr 5:124,717,203...124,735,743

G

GTP-binding protein 10 (putative)

increases expression

alpha-Chlorohydrin results in increased expression of GTPBP10 protein

NCBI chr 5:5,587,454...5,609,541
Ensembl chr 5:5,587,454...5,609,538

G

GTP binding protein 3

decreases expression

alpha-Chlorohydrin results in decreased expression of GTPBP3 protein

NCBI chr 8:71,938,788...71,952,268
Ensembl chr 8:71,940,747...71,952,227

G

glucuronidase, beta

increases expression

alpha-Chlorohydrin results in increased expression of GUSB protein

NCBI chr 5:130,011,278...130,031,890
Ensembl chr 5:130,017,852...130,031,890

G

granzyme A

decreases expression

alpha-Chlorohydrin results in decreased expression of GZMA mRNA

NCBI chr13:113,230,358...113,237,515
Ensembl chr13:113,230,359...113,237,515

G

granzyme B

increases expression

alpha-Chlorohydrin results in increased expression of GZMB mRNA

NCBI chr14:56,496,293...56,499,791
Ensembl chr14:56,496,295...56,499,717

G

histocompatibility 13

increases expression

alpha-Chlorohydrin results in increased expression of HM13 protein

NCBI chr 2:152,511,292...152,550,590
Ensembl chr 2:152,511,381...152,550,590

G

H1.0 linker histone

decreases expression

alpha-Chlorohydrin results in decreased expression of H1F0 mRNA

NCBI chr15:78,912,412...78,914,704
Ensembl chr15:78,912,650...78,914,704

G

H1.5 linker histone, cluster member

increases expression

alpha-Chlorohydrin results in increased expression of H1F5 protein

NCBI chr13:21,964,002...21,964,795
Ensembl chr13:21,964,053...21,964,795

G

histocompatibility 2, Q region locus 1

increases expression

alpha-Chlorohydrin results in increased expression of RT1-CE16 mRNA

NCBI chr17:35,539,503...35,547,118
Ensembl chr17:35,539,381...35,544,075

G

3-hydroxyanthranilate 3,4-dioxygenase

increases expression
decreases expression

alpha-Chlorohydrin analog results in increased expression of HAAO protein; alpha-Chlorohydrin results in increased expression of HAAO protein
alpha-Chlorohydrin results in decreased expression of HAAO protein

PMID:26597043 PMID:34915118

NCBI chr17:84,138,777...84,157,589
Ensembl chr17:84,138,585...84,155,392

G

3-hydroxyacyl-CoA dehydratase 4

decreases expression

alpha-Chlorohydrin results in decreased expression of HACD4 mRNA

NCBI chr 4:88,325,924...88,357,175
Ensembl chr 4:88,314,381...88,357,165

G

hydroxyacyl-Coenzyme A dehydrogenase

decreases expression
increases expression

alpha-Chlorohydrin analog results in decreased expression of HADH protein; alpha-Chlorohydrin results in decreased expression of HADH protein
alpha-Chlorohydrin results in increased expression of HADH mRNA

PMID:26597043 PMID:28522335 PMID:34915118

NCBI chr 3:131,027,068...131,065,750
Ensembl chr 3:131,027,068...131,065,750

G

histidine ammonia lyase

decreases expression

alpha-Chlorohydrin analog results in decreased expression of HAL protein

NCBI chr10:93,324,630...93,352,623
Ensembl chr10:93,324,630...93,355,166

G

hydroxyacid oxidase 2

decreases expression

alpha-Chlorohydrin results in decreased expression of HAO2 protein

NCBI chr 3:98,781,835...98,802,692
Ensembl chr 3:98,781,837...98,800,555

G

histidyl-tRNA synthetase 2

increases expression

alpha-Chlorohydrin results in increased expression of HARS2 protein

NCBI chr18:36,916,257...36,925,615
Ensembl chr18:36,916,061...36,925,615

G

hepatitis A virus cellular receptor 1

increases expression
multiple interactions

alpha-Chlorohydrin analog results in increased expression of HAVCR1 mRNA; alpha-Chlorohydrin results in increased expression of HAVCR1 protein
alpha-Chlorohydrin promotes the reaction [glycidol results in increased expression of HAVCR1 protein]; glycidol promotes the reaction [alpha-Chlorohydrin results in increased expression of HAVCR1 protein]

PMID:29860048 PMID:33187795

NCBI chr11:46,630,644...46,670,405
Ensembl chr11:46,625,907...46,670,405

G

HCLS1 associated X-1

increases expression

alpha-Chlorohydrin results in increased expression of HAX1 protein

NCBI chr 3:89,902,753...89,906,023
Ensembl chr 3:89,902,753...89,906,087

G

host cell factor C1

increases expression

alpha-Chlorohydrin results in increased expression of HCFC1 protein

NCBI chr X:72,986,400...73,011,430
Ensembl chr X:72,986,398...73,009,963

G

host cell factor C2

increases expression

alpha-Chlorohydrin results in increased expression of HCFC2 protein

NCBI chr10:82,534,841...82,631,699
Ensembl chr10:82,531,994...82,578,262

G

haloacid dehalogenase-like hydrolase domain containing 3

decreases expression
increases expression

alpha-Chlorohydrin results in decreased expression of HDHD3 protein
alpha-Chlorohydrin analog results in increased expression of HDHD3 protein

NCBI chr 4:62,417,291...62,420,437
Ensembl chr 4:62,417,245...62,421,704

G

high density lipoprotein (HDL) binding protein

increases expression

alpha-Chlorohydrin results in increased expression of HDLBP protein

NCBI chr 1:93,333,662...93,406,639
Ensembl chr 1:93,333,662...93,406,537

G

HEAT repeat containing 1

increases expression

alpha-Chlorohydrin results in increased expression of HEATR1 protein

NCBI chr13:12,410,256...12,453,774
Ensembl chr13:12,409,908...12,455,170

G

hephaestin

decreases expression

alpha-Chlorohydrin results in decreased expression of HEPH protein

NCBI chr X:95,499,042...95,618,091
Ensembl chr X:95,498,965...95,618,091

G

hexosaminidase A

increases expression

alpha-Chlorohydrin results in increased expression of HEXA mRNA

NCBI chr 9:59,446,966...59,472,392
Ensembl chr 9:59,446,823...59,472,392

G

hexosaminidase B

increases expression

alpha-Chlorohydrin results in increased expression of HEXB mRNA

NCBI chr13:97,312,839...97,334,865
Ensembl chr13:97,312,839...97,334,865

G

homogentisate 1, 2-dioxygenase

decreases expression

alpha-Chlorohydrin results in decreased expression of HGD protein

NCBI chr16:37,400,104...37,452,388
Ensembl chr16:37,400,515...37,452,382

G

3-hydroxyisobutyryl-Coenzyme A hydrolase

increases expression

alpha-Chlorohydrin results in increased expression of HIBCH protein

NCBI chr 1:52,884,197...52,960,145
Ensembl chr 1:52,884,088...52,960,145

G

histone cell cycle regulator

decreases expression

alpha-Chlorohydrin results in decreased expression of HIRA protein

NCBI chr16:18,695,500...18,789,059
Ensembl chr16:18,695,787...18,789,059

G

hexokinase 1

decreases expression

alpha-Chlorohydrin results in decreased expression of HK1 mRNA

NCBI chr10:62,104,634...62,215,699
Ensembl chr10:62,104,634...62,215,687

G

5-hydroxymethylcytosine (hmC) binding, ES cell specific

increases expression

alpha-Chlorohydrin results in increased expression of HMCES protein

NCBI chr 6:87,890,889...87,913,603
Ensembl chr 6:87,890,917...87,913,611

G

3-hydroxy-3-methylglutaryl-Coenzyme A reductase

multiple interactions

[Coconut Oil co-treated with alpha-Chlorohydrin analog] results in increased expression of HMGCR mRNA

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